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neoprom 2014

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https://www.readbyqxmd.com/read/21235822/neoprom-neonatal-oxygenation-prospective-meta-analysis-collaboration-study-protocol
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Lisa M Askie, Peter Brocklehurst, Brian A Darlow, Neil Finer, Barbara Schmidt, William Tarnow-Mordi
BACKGROUND: The appropriate level of oxygenation for extremely preterm neonates (<28 weeks' gestation) to maximise the greatest chance of survival, without incurring significant morbidity, remains unknown. Infants exposed to lower levels of oxygen (targeting oxygen saturations of <90%) in the first weeks of life are at increased risk of death, cerebral palsy, patent ductus arteriosus, pulmonary vascular resistance and apnoea, whilst those maintained in higher levels of oxygen (targeting oxygen saturations of >90%) have been reported to have greater rates of morbidity including retinopathy of prematurity and chronic lung disease...
2011: BMC Pediatrics
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