Read by QxMD icon Read

phytic acid

Gabriela M Chiocchetti, Elisabete A De Nadai Fernandes, Anna A Wawer, Susan Fairweather-Tait, Tatiana Christides
Background : Iron deficiency is a public health problem in many low- and middle-income countries. Introduction of agro-industrial food by-products, as additional source of nutrients, could help alleviate this micronutrient deficiency, provide alternative sources of nutrients and calories in developed countries, and be a partial solution for disposal of agro-industry by-products. Methods : The aim of this study was to determine iron bioavailability of 5 by-products from Brazilian agro-industry (peels from cucumber, pumpkin, and jackfruit, cupuaçu seed peel, and rice bran), using the in vitro digestion/ Caco-2 cell model; with Caco-2 cell ferritin formation as a surrogate marker of iron bioavailability...
May 16, 2018: Medicines (Basel, Switzerland)
Yukako Okazaki, Ayaka Sekita, Tetsuyuki Katayama
Dietary phytic acid (PA) was recently reported by our group to suppress hepatic lipogenic gene expression and modulate gut microbiota in rats fed a high-sucrose (HSC) diet. The present study aimed to investigate whether the modulatory effects of PA depend on the dietary carbohydrate source and are attributed to the myo-inositol (MI) ring of PA. Male Sprague-Dawley rats were fed an HSC or a high-starch (HSR) diet with or without 1.02% sodium PA for 12 days. Subsequently, the rats were fed the HSC diet, the HSC diet containing 1...
May 2018: Biomedical Reports
Katie L Moore, Ildefonso Rodríguez-Ramiro, Eleanor R Jones, Emily J Jones, Jorge Rodríguez-Celma, Kirstie Halsey, Claire Domoney, Peter R Shewry, Susan Fairweather-Tait, Janneke Balk
Pea seeds are widely consumed in their immature form, known as garden peas and petit pois, mostly after preservation by freezing or canning. Mature dry peas are rich in iron in the form of ferritin, but little is known about the content, form or bioavailability of iron in immature stages of seed development. Using specific antibodies and in-gel iron staining, we show that ferritin loaded with iron accumulated gradually during seed development. Immunolocalization and high-resolution secondary ion mass spectrometry (NanoSIMS) revealed that iron-loaded ferritin was located at the surface of starch-containing plastids...
May 2, 2018: Scientific Reports
Luana Nionelli, Marco Montemurro, Erica Pontonio, Michela Verni, Marco Gobbetti, Carlo Giuseppe Rizzello
Lactic acid bacteria were isolated from hemp (Cannabis sativa L.) flour, spontaneously fermented dough, and type I sourdough. Isolates were identified and further selected based on pro-technological, nutritional and functional properties. Lactobacillus plantarum/s5, Pediococcus acidilactici/s5, and Leuconostoc mesenteroides/s1 were used as mixed starter to produce hemp sourdough. Significant decreases of the concentration of phytic acid, condensed tannins, and total saponins were observed during fermentation...
April 24, 2018: International Journal of Food Microbiology
Alex Sander Rodrigues Cangussu, Deborah Aires Almeida, Raimundo Wagner de Souza Aguiar, Sidnei Emilio Bordignon-Junior, Kelvinson Fernandes Viana, Luiz Carlos Bertucci Barbosa, Edson Wagner da Silva Cangussu, Igor Viana Brandi, Augustus Caeser Franke Portella, Gil Rodrigues Dos Santos, Eliane Macedo Sobrinho, William James Nogueira Lima
Phytase plays a prominent role in monogastric animal nutrition due to its ability to improve phytic acid digestion in the gastrointestinal tract, releasing phosphorus and other micronutrients that are important for animal development. Moreover, phytase decreases the amounts of phytic acid and phosphate excreted in feces. Bioinformatics approaches can contribute to the understanding of the catalytic structure of phytase. Analysis of the catalytic structure can reveal enzymatic stability and the polarization and hydrophobicity of amino acids...
2018: Enzyme Research
Ke Chen, Shuhao Zhang, Anran Li, Xuke Tang, Lidong Li, Lin Guo
Many biological organisms usually derived from the ordered assembly of heterogeneous, hierarchical inorganic/organic constituents exhibit outstanding mechanical integration, but have proven to be difficult to produce the combination of excellent mechanical properties, such as strong, tough, and lightweight by merely mimicking their component and structural characteristics. Herein, inspired by biologically strong chelating interactions of phytic acid (PA) or IP6 in many biomaterials, we present a biologically interfacial chelating-like reinforcement (BICR) strategy for fabrication of a highly-dense ordered "brick-and-mortar" (BM) microstructure by incorporating tiny amounts of natural chelating agent (e...
April 26, 2018: ACS Nano
Bijender Singh, K K Sharma, Amit Kumari, Anil Kumar, S K Gakhar
A thermostable and protease-resistant HAP-phytase of Sporotrichum thermophile was over-expressed in Pichia pastoris ×33. Purified recombinant phytase displayed all its biochemical properties similar to wild type. Molecular modeling and docking of phytase with various substrates showed differential binding patterns with GoldScore values ranging from 40.61 to 79.78. Docking with different substrates revealed strong binding affinity with ATP and phytic acid, while the lowest with AMP and phosphoenol pyruvate...
April 17, 2018: International Journal of Biological Macromolecules
Anita Spychaj, Edward Pospiech, Ewa Iwańska, Magdalena Montowska
At present, allergic response to food components is an increasing problem all over the world. Therefore it is important to protect people vulnerable to food allergens against accidental and unintended consumption of products containing allergic ingredients. The meat industry commonly uses various allergic additives in production of processed products, i.e. legumes (soy, peas, beans), milk and egg preparations, cereals containing gluten (wheat, rye, barley and oats), and spices (celery and mustard). These meat additives have specific technological properties which help to create a texture, flavour profile or affect the nutritional value, although some of them, such as soy, mustard, milk and egg white proteins can cause severe allergic reactions...
April 19, 2018: Journal of the Science of Food and Agriculture
Mary J Espina, C M Sabbir Ahmed, Angelina Bernardini, Ekundayo Adeleke, Zeinab Yadegari, Prakash Arelli, Vince Pantalone, Ali Taheri
Soybean is an important oil-producing crop in the Fabaceae family and there are increasing demands for soybean oil and other soybean products. Genetic improvement of soybean is needed to increase its production. In order to provide genetic diversity and resources for identifying important genes, a new ethyl methane sulfonate (EMS) mutagenized soybean population was generated using the newly released germplasm, JTN-5203 (maturity group V). Treatment of soybean seeds with 60 mM EMS concentration was found to be suitable for inducing mutation...
2018: Frontiers in Plant Science
Siva K Angalakurthi, Connie A Tenorio, Michael Blaber, C Russell Middaugh
In this study, we examined the local dynamics of acidic fibroblast growth factor (FGF-1) as well as the binding sites of various polyanions including poly-sulfates (heparin and low MW heparin) and poly-phosphates (phytic acid and ATP) using hydrogen-deuterium exchange mass spectrometry (HX-MS). For local dynamics, results are analyzed at the peptide level as well as in terms of buried amides employing crystallographic B-factors and compared with a residue level heat map generated from HX-MS results. Results show that strand 4 and 5 and the turn between them to be the most flexible regions as was previously seen by NMR...
April 12, 2018: Protein Science: a Publication of the Protein Society
Beenu Tanwar, Rajni Modgil, Ankit Goyal
The present investigation was aimed to study the effect of detoxification on the nutrients and antinutrients of wild apricot kernel followed by its hypocholesterolemic effect in male Wistar albino rats. The results revealed a non-significant (p > 0.05) effect of detoxification on the proximate composition except total carbohydrates and protein content. However, detoxification led to a significant (p < 0.05) decrease in l-ascorbic acid (76.82%), β-carotene (25.90%), dietary fiber constituents (10.51-28...
April 25, 2018: Food & Function
Grzegorz Kłosowski, Dawid Mikulski, Oliwia Jankowiak
One of the key steps in the production of phytases of microbial origin is selection of culture parameters, followed by isolation of the enzyme and evaluation of its catalytic activity. It was found that conditions for S. cerevisiae yeast culture, strain Finarome, giving the reduction in phytic acid concentration of more than 98% within 24 h of incubation were as follows: pH 5.5, 32 °C, continuous stirring at 80 rpm, the use of mannose as a carbon source and aspartic acid as a source of nitrogen. The highest catalytic activity of the isolated phytase was observed at 37 °C, pH 4...
April 8, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Fengbo Zhu, Ji Lin, Zi Liang Wu, Shaoxing Qu, Jun Yin, Jin Qian, Qiang Zheng
Conductive polymer hydrogels (CPHs) that combine the unique properties of hydrogels and electronic properties of conductors have shown their great potentials in wearable/implantable electronic devices, where materials with remarkable mechanical properties, high conductivity and easy processability are demanding. Here we have developed a new type of polyion complex/polyaniline (PIC/PAni) hybrid hydrogels that are tough, conductive and can be facilely patterned. The incorporation of conductive phase (PAni) into PIC matrix through phytic acid resulted in hybrid gels with ~65 wt% water, high conductivity while maintaining the key viscoelasticity of the tough matrix...
April 2, 2018: ACS Applied Materials & Interfaces
Zhiwen Wang, Hongwei Zhou, Weixing Chen, QiuZhao Li, Bo Yan, Xilang Jin, Aijie Ma, Hanbin Liu, Weifeng Zhao
The first example of dually synergetic network hydrogel, which has integrated mechanical stretchability, thermal responsiveness and electrical conductivity, has been constructed by a versatile and topological co-crosslinking approach. Poly(N-isopropylacrylamide) (PNIPAAm) is introduced as the thermally responsive ingredient and polyaniline (PANI) is selected as the electrically conductive ingredient. PNIPAAm network is crosslinked by double bond end-capped Pluronic F127 (F127DA). PANI network is doped and crosslinked by phytic acid...
April 2, 2018: ACS Applied Materials & Interfaces
Lan Shi, Susan D Arntfield, Michael Nickerson
Raw and processed (soaked or cooked) seeds of peas, lentils, chickpeas, fava beans and common beans were studied for their contents of antinutritional factors (lectins, phytic acid, total and soluble oxalates), along with soybean as a control. Analysis of variance indicated that legume type, treatment and their interactive effects were significant on these antinutrients. The raw soybean seed was found to contain the highest levels of lectins (692.8 HU/mg), phytic acid (22.91 mg/g), total oxalate (370.5 mg/100 g) and soluble oxalate (200...
May 2018: Food Research International
Qiang Xia, Yunfei Li
This investigation aimed to examine the effects of a novel processing pattern, combining high hydrostatic pressure (HHP) with germination, on the embryo growth and physicochemical characteristics of wholegrain brown rice (WBR). WBR grains were firstly subjected to mild HHP stress (30-90 MPa/5 min) and then incubated at 37 °C for 52 h for obtaining germinated samples (GBR). The results showed that HHP shock resulted in a delayed embryo growth of WBR grains, maintaining acceptable sprouting rates ranging from 65% to 76% when germination was finished...
April 2018: Food Research International
Eleonora Cominelli, Massimo Confalonieri, Martina Carlessi, Gaia Cortinovis, Maria Gloria Daminati, Timothy G Porch, Alessia Losa, Francesca Sparvoli
Phytic acid (InsP6 ) is the main storage form of phosphate in seeds. In the plant it plays an important role in response to environmental stress and hormonal changes. InsP6 is a strong chelator of cations, reducing the bioavailability of essential minerals in the diet. Only a common bean low phytic acid (lpa1) mutant, affected in the PvMRP1 gene, coding for a putative tonoplastic phytic acid transporter, was described so far. This mutant is devoid of negative pleiotropic effects normally characterising lpa mutants...
May 2018: Plant Science: An International Journal of Experimental Plant Biology
Yuanlin Ren, Tongguo Huo, Yiwen Qin, Xiaohui Liu
This paper aims to develop a novel method, i.e., sol-gel combined with layer-by-layer assembly technology, to impart flame retardancy on polyacrylonitrile (PAN) fabrics. Silica-sol was synthesized via the sol-gel process and acted as cationic solution, and phytic acid (PA) was used as the anionic medium. Flame-retardant-treated PAN fabric (FR-PAN) could achieve excellent flame retardancy with 10 bilayer (10BL) coating through layer-by-layer assembly. The structure of the fabrics was characterized by X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared spectroscopy (FTIR)...
March 23, 2018: Materials
Sipla Aggarwal, Anil Kumar, Kaushal K Bhati, Gazaldeep Kaur, Vishnu Shukla, Siddharth Tiwari, Ajay K Pandey
Enhancement of micronutrient bioavailability is crucial to address the malnutrition in the developing countries. Various approaches employed to address the micronutrient bioavailability are showing promising signs, especially in cereal crops. Phytic acid (PA) is considered as a major antinutrient due to its ability to chelate important micronutrients and thereby restricting their bioavailability. Therefore, manipulating PA biosynthesis pathway has largely been explored to overcome the pleiotropic effect in different crop species...
2018: Frontiers in Plant Science
Dongsheng Zhang, Weixiang Li, Zhanfang Ma
An improved sandwich-type electrochemical immunosensor based on the novel signal amplification strategy was developed. Methylene blue (MB) loaded mesoporous silica nanoparticles (MSN) with polydopamine coating (PDA) were employed as "smart" labels, while phytic acid doped polyaniline hydrogel (PANI) with high adsorption capacity was acted as substrate. In this strategy, amount of redox species (MB) encapsulated in MSN by PDA will be released under acidic condition and then absorbed stably by PANI...
March 13, 2018: Biosensors & Bioelectronics
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"