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phytic acid

Sipla Aggarwal, Anil Kumar, Kaushal K Bhati, Gazaldeep Kaur, Vishnu Shukla, Siddharth Tiwari, Ajay K Pandey
Enhancement of micronutrient bioavailability is crucial to address the malnutrition in the developing countries. Various approaches employed to address the micronutrient bioavailability are showing promising signs, especially in cereal crops. Phytic acid (PA) is considered as a major antinutrient due to its ability to chelate important micronutrients and thereby restricting their bioavailability. Therefore, manipulating PA biosynthesis pathway has largely been explored to overcome the pleiotropic effect in different crop species...
2018: Frontiers in Plant Science
Dongsheng Zhang, Weixiang Li, Zhanfang Ma
An improved sandwich-type electrochemical immunosensor based on the novel signal amplification strategy was developed. Methylene blue (MB) loaded mesoporous silica nanoparticles (MSN) with polydopamine coating (PDA) were employed as "smart" labels, while phytic acid doped polyaniline hydrogel (PANI) with high adsorption capacity was acted as substrate. In this strategy, amount of redox species (MB) encapsulated in MSN by PDA will be released under acidic condition and then absorbed stably by PANI...
March 13, 2018: Biosensors & Bioelectronics
Rajib Podder, Diane M DellaValle, Robert T Tyler, Raymond P Glahn, Elad Tako, Albert Vandenberg
Due to low Fe bioavailability and low consumption per meal, lentil must be fortified to contribute significant bioavailable Fe in the Bangladeshi diet. Moreover, since red lentil is dehulled prior to consumption, an opportunity exists at this point to fortify lentil with Fe. Thus, in the present study, lentil was Fe-fortified (using a fortificant Fe concentration of 2800 µg g-1 ) and used in 30 traditional Bangladeshi meals with broad differences in concentrations of iron, phytic acid (PA), and relative Fe bioavailability (RFeB%)...
March 15, 2018: Nutrients
Sourav Mandal, Susanne Meininger, Uwe Gbureck, Bikramjit Basu
One of the important aspects in 3D powder printing (3DPP) is the selection of binder for a specific material composition to produce scaffolds with desired microstructure and physico-chemical properties. To this end, a new powder-binder combination, namely tetracalcium phosphate (TTCP) and phytic acid (IP6) was investigated at ambient temperature, for low load bearing application. A minimal deviation (<200 µm, w.r.t. computer aided design) was observed in the final sample through optimization of 3DPP process, along with minimum strut and macro-pore size of 200 and 750 µm, respectively...
March 8, 2018: Journal of Materials Science. Materials in Medicine
Kumar Raja Puppala, V Ravi Kumar, Jayant Khire, Mahesh Dharne
Increase of undigested complexes of phytic acid in food is gaining serious attention to overcome nutritional challenges due to chelation effects. We investigated soil-borne yeast phytase from Saccharomyces cerevisiae (NCIM 3662) for dephytinization of foods, probiotic properties, and process development. The strain produced 45 IU/DCG by cell-bound phytase in an unoptimized medium was increased fourfold (164 IU/DCG) in 12 h using statistical media optimization. The process was scaled-up up to 10-L fermenter scale with increased phytase productivity of 6...
March 5, 2018: Probiotics and Antimicrobial Proteins
Yaping Wang, Lilan Zeng, Honghua Zhang, Junhuai Xiang, Shufang Zhang, Wenhui Chang, Rongfa Zhang, Qiao Wang, Yang Sheng, Ying Zhao
In order to clarify the mechanism that zinc and phosphorus elements entering the micro-arc oxidation (MAO) coatings developed on Ti-6Al-4V alloys, anodic coatings containing different zinc and phosphorus were fabricated using an orthogonal experiment of four factors with three levels in an electrolyte containing EDTA-ZnNa₂, KOH, and phytic acid. Surface morphology, element composition, chemical state and phase structure of MAO coatings were characterized by scanning electron microscope (SEM), energy dispersive X-ray spectrometer (EDS), X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD)...
February 27, 2018: Materials
Elaine Kaspchak, Luciana Igarashi Mafra, Marcos Rogério Mafra
Bioavailability of food nutrients can be reduced in the presence of antinutrients such as phytates and tannins. This work aimed to study bovine serum albumin binding to phytic acid and tannic acid, and its influence on in vitro protein digestibility. The effect of autoclaving and boiling on protein digestibility and the microstructure of complexes was also evaluated. Results showed that high ionic strength promotes greater affinity between tannic acid and bovine serum albumin, and decreases in vitro protein digestibility...
June 30, 2018: Food Chemistry
Alok Kumar Yadav, Preeti Sirohi, Saurabh Saraswat, Manjoo Rani, Manish Pratap Singh, Sameer Srivastava, Nand K Singh
The antibiotic resistance in bacteria responsible for causing community and health care-associated infection displayed a major threat to global health. Use of broad-spectrum antibiotics for the treatment of various ailments poses serious side effects. In the present research, we investigated the combined role of 2% phytic acid with 2% methanolic seed extract of Syzygium cumini and 0.5% sodium chloride for inhibition of Bacillus subtilis and Pseudomonas aeruginosa and found it to be efficient over B. subtilis...
February 20, 2018: Current Microbiology
Remo Chiozzotto, Mario Ramírez, Chouhra Talbi, Eleonora Cominelli, Lourdes Girard, Francesca Sparvoli, Georgina Hernández
The common bean ( Phaseolus vulgaris L.) low phytic acid ( lpa1 ) biofortified genotype produces seeds with improved nutritional characteristics and does not display negative pleiotropic effects. Here we demonstrated that lpa1 plants establish an efficient nitrogen-fixing symbiosis with Rhizobium etli CE3. The lpa1 nodules showed a higher expression of nodule-function related genes than the nodules of the parental wild type genotype (BAT 93). We analyzed the response to water stress of lpa1 vs. BAT 93 plants grown under fertilized or under symbiotic N₂-fixation conditions...
February 15, 2018: Genes
Yongshen Li, Yunna Song, Jihui Li, Yuehai Li, Ning Li, Shuai Niu
In this article, polyvinyl alcohol/phytic acid polymer (PVA/PA polymer) is synthesized from PVA and PA via the esterification reaction of PVA and PA in the case of acidity and ultrasound irradiation, and PVA/PA polymer sponge is prepared via foaming PVA/PA polymer in the presence of n-pentane and ammonium bicarbonate, and the structure of PVA/PA polymer and the structure, morphology and crystallinity of PVA/PA polymer sponge are characterized, and the thermal stability and surface resistivity of PVA/PA polymer sponge are investigated...
April 2018: Ultrasonics Sonochemistry
Da Su, Lujian Zhou, Qian Zhao, Gang Pan, Fangmin Cheng
Development of rice cultivars with low phytic acid (lpa) is considered as a primary strategy for biofortification of zinc (Zn) and iron (Fe). Here, two rice genotypes (XS110 and its lpa mutant) were used to investigate the effect of P supplies on accumulations and distributions of PA, Zn and Fe in rice grains by using hydroponics and detached panicle culture system. Results showed that higher P level increased grain PA concentration on dry matter basis (g/kg), but it markedly decreased PA accumulation on per grain basis (mg/grain)...
February 5, 2018: Journal of Agricultural and Food Chemistry
Molly Gabaza, Habtu Shumoy, Maud Muchuweti, Peter Vandamme, Katleen Raes
The present study is an evaluation of iron and zinc bioaccessibility of fermented maize, sorghum, pearl millet and finger millet from five different locations in Zimbabwe. Iron and zinc contents ranged between 3.22 and 49.7 and 1.25-4.39mg/100gdm, respectively. Fermentation caused a reduction of between 20 and 88% of phytic acid (PA) while a general increase in soluble phenolic compounds (PC) and a decrease of the bound (PC) was observed. Bioaccessibility of iron and zinc ranged between 2.77 and 26.1% and 0...
January 2018: Food Research International
Chengtian Zhang, Zonghua Pu, Ibrahim Saana Amiinu, Yufeng Zhao, Jiawei Zhu, Yongfu Tang, Shichun Mu
Transition metal phosphides (TMPs) are considered to be superb catalysts for water splitting. In this work, we introduce an efficient strategy to fabricate dicobalt phosphide (Co2P) quantum dots embedded in N, P dual-doped carbon (Co2P@NPC) on carbon cloth (Co2P@NPC/CC) by in situ carbonization of cobalt ion induced phytic acid (PA) and polyaniline (PANI) macromolecule precursors. As a highly efficient self-supported electrode, it has a low onset overpotential (74 mV at 1 mA cm-2) approaching that of the commercial Pt/C catalyst for the hydrogen evolution reaction (HER) in acidic media...
January 25, 2018: Nanoscale
Nibras Belgaroui, Benoit Lacombe, Hatem Rouached, Moez Hanin
Engineering osmotolerant plants is a challenge for modern agriculture. An interaction between osmotic stress response and phosphate homeostasis has been reported in plants, but the identity of molecules involved in this interaction remains unknown. In this study we assessed the role of phytic acid (PA) in response to osmotic stress and/or phosphate deficiency in Arabidopsis thaliana. For this purpose, we used Arabidopsis lines (L7 and L9) expressing a bacterial beta-propeller phytase PHY-US417, and a mutant in inositol polyphosphate kinase 1 gene (ipk1-1), which were characterized by low PA content, 40% (L7 and L9) and 83% (ipk1-1) of the wild-type (WT) plants level...
January 18, 2018: Scientific Reports
Ishara Perera, Saman Seneweera, Naoki Hirotsu
Myo-inositol hexaphosphate, also known as phytic acid (PA), is the most abundant storage form of phosphorus in seeds. PA acts as a strong chelator of metal cations to form phytate and is considered an anti-nutrient as it reduces the bioavailability of important micronutrients. Although the major nutrient source for more than one-half of the global population, rice is a poor source of essential micronutrients. Therefore, biofortification and reducing the PA content of rice have arisen as new strategies for increasing micronutrient bioavailability in rice...
January 11, 2018: Rice
Qiuhong Yao, Yufeng Feng, Connieal Tan, Shujun Xia, Li Zhao, Shuya Wang, Yiru Wang, Xi Chen
In this study, an on-line SPE-disc filled with phytic acid induced 3D graphene-based foam (PAGF) has been applied to the determination of the migration of bisphenol A (BPA) in disposable syringes. The approach is of quick, easy, sensitive and environmentally-friendly. Experimental conditions were investigated and optimized including the character of enriched material and the amount of migrated BPA under different temperature, time and pH conditions. The experimental results reveal that the approach presents a wide linear range between the signal response and the concentration of BPA from 1 to 1000ngmL-1, as well as the detection limit of 0...
March 1, 2018: Talanta
Ashish Marathe, Veda Krishnan, T Vinutha, Anil Dahuja, Monica Jolly, Archana Sachdev
Phytic acid (PA) is implicative in a spectrum of biochemical and physiological processes involved in plant stress response. Inositol 1,3,4, Tris phosphate 5/6 kinase (ITPK), a polyphosphate kinase that converts Inositol 1,3,4 trisphosphate to Inositol 1,3,4,5/6 tetra phosphate, averting the inositol phosphate pool towards PA biosynthesis, is a key regulator that exists in four different isoforms in soybean. In the present study, in-silico analysis of the promoter region of ITPKs was done and among the four isoforms, promoter region of GmITPK2 showed the presence of two MYB binding elements for drought inducibility and one for ABA response...
December 19, 2017: Plant Physiology and Biochemistry: PPB
Lujia Li, Qingxue Fu, Mengxin Xia, Lei Xin, Hongyi Shen, Guowen Li, Guang Ji, Qianchao Meng, Yan Xie
Phytic acid (IP6) is a natural phosphorylated inositol which abundantly present in most cereal grains and seeds. This study investigated the effects of IP6 regulation on P-gp and its potential mechanisms using in situ and in vitro models. The effective permeability of the typical P-gp substrate rhodamine 123 (R123) in colon was significantly increased from (1.69 ± 0.22) × 10-5cm/s in the control group to (3.39 ± 0.417) ×10-5cm/s (p < 0.01) in the 3.5 mM IP6 group. Additionally, IP6 can concentration-dependently decrease the R123 efflux ratio in both Caco-2 and MDCK II-MDR1 cell monolayers and increase intracellular R123 accumulation in Caco-2 cells...
December 28, 2017: Journal of Agricultural and Food Chemistry
Neelam Redekar, Guillaume Pilot, Victor Raboy, Song Li, M A Saghai Maroof
A dominant loss of function mutation in myo-inositol phosphate synthase (MIPS) gene and recessive loss of function mutations in two multidrug resistant protein type-ABC transporter genes not only reduce the seed phytic acid levels in soybean, but also affect the pathways associated with seed development, ultimately resulting in low emergence. To understand the regulatory mechanisms and identify key genes that intervene in the seed development process in low phytic acid crops, we performed computational inference of gene regulatory networks in low and normal phytic acid soybeans using a time course transcriptomic data and multiple network inference algorithms...
2017: Frontiers in Plant Science
Rahel Getu, Yetenayet B Tola, Satheesh Neela
BACKGROUND: Soy milk-based beverages play an important role as a healthy food alternative for human consumption. However, the &lsquo;beany&rsquo; flavor and chalky mouth feel of soy milk often makes it unpalatable to consumers. The objective of the present study is to optimize a blend of soy milk, mango nectar and sucrose solution for the best quality soy milk-based beverage. METHODS: This study was designed to develop a soy milk blended beverage, with mango nectar and sucrose solutions, with the best physicochemical and sensory properties...
October 2017: Acta Scientiarum Polonorum. Technologia Alimentaria
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