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Lipoprotein ratios

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https://www.readbyqxmd.com/read/28742767/sedentary-occupation-workers-who-meet-the-physical-activity-recommendations-have-a-reduced-risk-for-metabolic-syndrome-a-cross-sectional-study
#1
Rodrigo Alberto Vieira Browne, Luiz Fernando Farias-Junior, Yuri Alberto Freire, Daniel Schwade, Geovani de Araújo Dantas de Macêdo, Vilma Bayma Montenegro, Thiago Jambo Alves Lopes, Filipe Fernandes Oliveira Dantas, Eduardo Caldas Costa
OBJECTIVE: We tested the hypothesis that sedentary occupation workers who meet the physical activity recommendations present a lower risk for metabolic syndrome (MetS) than their nonactive counterparts. METHODS: A cross-sectional study involving 502 sedentary occupation workers. Physical activity level was self-reported. MetS was defined by International Diabetes Federation criteria. RESULTS: The active group showed lower odds for MetS [odds ratio (OR) 0...
July 24, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28742409/the-effects-of-vitamin-d-and-evening-primrose-oil-co-supplementation-on-lipid-profiles-and-biomarkers-of-oxidative-stress-in-vitamin-d-deficient-women-with-polycystic-ovary-syndrome-a-randomized-double-blind-placebo-controlled-trial
#2
Khadijeh Nasri, Sedighe Akrami, Maryam Rahimi, Mohsen Taghizadeh, Masoud Behfar, Mohammad Reza Mazandaranian, Abbas Kheiry, Mohammad Reza Memarzadeh, Zatollah Asemi
PURPOSE OF THE STUDY: There was inconsistent evidence about the benefit of vitamin D plus evening primrose oil (EPO) supplement intake on lipid profiles and reduced oxidative stress among women with polycystic ovary syndrome (PCOS). The current study was performed to evaluate the effects of vitamin D plus EPO supplementation on lipid profiles and biomarkers of oxidative stress in vitamin D-deficient women with PCOS. MATERIALS AND METHODS: This randomized, double-blind, placebo-controlled trial was performed among 60 vitamin D-deficient women with PCOS...
July 25, 2017: Endocrine Research
https://www.readbyqxmd.com/read/28741806/serum-%C3%AE-glutamyltransferase-level-and-metabolic-syndrome-in-children-and-adolescents-korean-national-health-and-nutrition-examination-survey
#3
Jae-Min Park, Jee-Yon Lee, Duk-Chul Lee, Yong-Jae Lee
AIMS/INTRODUCTION: Serum γ-glutamyltransferase (GGT) is positively related to cardiometabolic diseases such as type 2 diabetes mellitus, hypertension, and metabolic syndrome (MetS) in adult populations. Our aim was to investigate whether serum GGT is independently associated with MetS and its components in a nationally representative sample of South Korean children and adolescents. MATERIALS AND METHODS: The study included data from 1,618 participants (867 boys, 751 girls) aged 10-18 years from the 2010-2011 Korean National Health and Nutrition Examination Survey...
July 25, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28741239/type-2-diabetes-mellitus-and-simple-glucose-metabolism-parameters-may-reliably-predict-nonalcoholic-fatty-liver-disease-features
#4
Everton Cazzo, Laísa Simakawa Jimenez, Martinho Antonio Gestic, Murillo Pimentel Utrini, Fábio Henrique Mendonça Chaim, Felipe David Mendonça Chaim, José Carlos Pareja, Elinton Adami Chaim
OBJECTIVE: This study aims to investigate the correlation between features of NAFLD among individuals with morbid obesity and the surrogate IR markers homeostasis model assessment (HOMA), product of triglycerides and glucose (TyG), and triglyceride-to-high-density-lipoprotein ratio (TG/HDL-c). METHODS: A cross-sectional study, which enrolled 89 individuals who consecutively underwent bariatric surgery from February through December 2015, was conducted. NAFLD was assessed through histological examination of liver biopsies and correlated with the values of HOMA, TyG, and TG/HDL-c and their respective cutoff points for insulin resistance (IR)...
July 24, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28739054/plasma-trans-fatty-acid-concentrations-continue-to-be-associated-with-metabolic-syndrome-among-us-adults-after-reductions-in-trans-fatty-acid-intake
#5
Zefeng Zhang, Cathleen Gillespie, Quanhe Yang
No study examined and compared the association between intake of trans-fatty acids (TFAs) and risk of metabolic syndrome before and after significant reduction of TFA intakes in the US population. We hypothesized that the relationship might remain significant after substantial reduction of TFA intakes in the population. We used data on 1442 and 2233 adults aged ≥20 years from the National Health and Nutrition Examination Survey 1999-2000 and 2009-2010, respectively. Multivariable logistic regression analysis was used to assess the association between plasma TFA concentrations and metabolic syndrome, including each of its 5 components...
July 2017: Nutrition Research
https://www.readbyqxmd.com/read/28737859/association-between-dietary-glycemic-load-and-metabolic-syndrome-in-obese-children-and-adolescents
#6
Angela Cornejo-Monthedoro, Isel Negreiros-Sánchez, Carlos Del Águila, Marlit Ysla-Marquillo, Percy Mayta-Tristán
OBJETIVE: To study the association between the metabolic syndrome (MS) and the glycemic load (GL) of food intake among obese children and adolescents seen in consultation by the endocrinology team in a pediatric referral hospital in Lima, Peru. POPULATION AND METHOD: Cross-sectional study among obese children and adolescents (body mass index ≥ 95 percentile), 10-15 years old. The MS was classified according to criteria of the International Diabetes Federation...
August 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28737258/preclinical-alterations-in-myocardial-microstructure-in-people-with-metabolic-syndrome
#7
Jennifer E Ho, Youssef Rahban, Harpaul Sandhu, Pranoti G Hiremath, Nir Ayalon, Fuzhong Qin, Alejandro J Perez, Jill Downing, Deepa M Gopal, Susan Cheng, Wilson S Colucci
OBJECTIVE: Metabolic syndrome (MetS) can lead to myocardial fibrosis, diastolic dysfunction, and eventual heart failure. This study evaluated alterations in myocardial microstructure in people with MetS by using a novel algorithm to characterize ultrasonic signal intensity variation. METHODS: Among 254 participants without existing cardiovascular disease (mean age 42 ± 11 years, 75% women), there were 162 with MetS, 47 with obesity without MetS, and 45 nonobese controls...
July 24, 2017: Obesity
https://www.readbyqxmd.com/read/28733767/relationship-between-plasma-pentraxin-3-level-and-risk-of-chronic-kidney-disease-in-the-korean-elderly-the-dong-gu-study
#8
Ran Lee, Min-Ho Shin, Hee-Nam Kim, Young-Hoon Lee, Seong-Woo Choi, Hye-Ran Ahn, Sun-Seog Kweon
Purpose This study investigated the cross-sectional association between chronic kidney disease (CKD) and plasma pentraxin 3 (PTX3) levels in a Korean population, in a community-based cohort study. METHODS: A total of 1816 (891 men, 925 women) subjects were randomly selected from the cohort of participants for the final analyses. Plasma PTX3 concentration was determined using enzyme-linked immunosorbent assays. The participants were divided into four quartiles according to the PTX3 levels...
July 21, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28733430/atherogenic-lipoprotein-determinants-of-cardiovascular-disease-and-residual-risk-among-individuals-with-low-low-density-lipoprotein-cholesterol
#9
Patrick R Lawler, Akintunde O Akinkuolie, Audrey Y Chu, Svati H Shah, William E Kraus, Damian Craig, Latha Padmanabhan, Robert J Glynn, Paul M Ridker, Daniel I Chasman, Samia Mora
BACKGROUND: Levels of LDL (low-density lipoprotein) cholesterol in the population are declining, and increasing attention is being focused on residual lipid-related pathways of atherosclerotic cardiovascular disease risk beyond LDL cholesterol. Among individuals with low (<130 mg/dL) LDL cholesterol, we undertook detailed profiling of circulating atherogenic lipoproteins in relation to incident cardiovascular disease in 2 populations. METHODS AND RESULTS: We performed proton nuclear magnetic resonance spectroscopy to quantify concentrations of LDL and VLDL (very low-density lipoprotein) particle subclasses in 11 984 JUPITER trial participants (NCT00239681)...
July 21, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28733174/lipoprotein-insulin-resistance-score-and-risk-of-incident-diabetes-during-extended-follow-up-of-20%C3%A2-years-the-women-s-health-study
#10
Paulo H N Harada, Olga V Demler, Sagar B Dugani, Akintunde O Akinkuolie, Manickavasagar V Moorthy, Paul M Ridker, Nancy R Cook, Aruna D Pradhan, Samia Mora
BACKGROUND: Type II diabetes (T2D) is preceded by prolonged insulin resistance and relative insulin deficiency incompletely captured by glucose metabolism parameters, high-density lipoprotein (HDL) cholesterol and triglycerides. OBJECTIVE: Whether lipoprotein insulin resistance (LPIR) score, a metabolomic marker, is associated with incident diabetes and improves risk reclassification over traditional markers on extended follow-up. METHODS: Among 25,925 nondiabetic women aged 45 years or older, LPIR was measured by nuclear magnetic resonance spectroscopy as a weighted score of very low density lipoprotein, low-density lipoprotein, and HDL particle sizes, and their subsets concentrations...
June 21, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28732570/incident-type-2-diabetes-is-associated-with-hdl-but-not-with-its-anti-oxidant-constituent-paraoxonase-1-the-prospective-cohort-prevend-study
#11
Setor K Kunutsor, Lyanne M Kieneker, Stephan J L Bakker, Richard W James, Robin P F Dullaart
OBJECTIVE: High-density lipoprotein cholesterol (HDL-C) is an established risk marker for cardiovascular disease and consistently associated with type 2 diabetes risk. Serum paraoxonase-1 (PON-1) - an anti-oxidant constituent of HDL - is inversely associated with cardiovascular disease risk, but its relationship with incident type 2 diabetes is uncertain. We aimed to investigate the prospective association between PON-1 and type 2 diabetes risk. METHODS: PON-1 was measured as its arylesterase activity at baseline in the Prevention of Renal and Vascular End-stage Disease (PREVEND) prospective study of 5947 predominantly Caucasian participants aged 28-75years with no pre-existing diabetes, that recorded 500 type 2 diabetes cases during a median follow-up of 11...
August 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28732566/association-of-circulating-irisin-levels-with-metabolic-and-metabolite-profiles-of-korean-adolescents
#12
Han Byul Jang, Hyo-Jin Kim, Jae Heon Kang, Sang Ick Park, Kyung Hee Park, Hye-Ja Lee
CONTEXT: Irisin, a novel exercise-induced myokine, has been suggested to regulate energy metabolism. OBJECTIVE: We studied the relationship between circulating irisin and metabolic and metabolite profiles of Korean adolescents, and investigated the effects of physical activity, obesity, and metabolic syndrome (MetS) on irisin levels. MATERIALS AND METHODS: Data were obtained from the Korean Children-Adolescents Study. Our cross-sectional study included 618 adolescents (370 normal-weight and 248 obese adolescents; 316 boys and 302 girls) aged 12-15years...
August 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28726527/the-comparison-and-estimation-of-the-prognostic-value-of-lipid-profiles-in-patients-with-prostate-cancer-depends-on-cancer-stage-advancement
#13
Edyta Idalia Wolny-Rokicka, Andrzej Tukiendorf, Jerzy Wydmański, Agnieszka Zembroń-Łacny
Lipid profiles and prostate cancer have a controversial relationship, and the predictive ability of lipids in determining cancer risk estimation is still questionable. This study demonstrates a significance assessment of the plasma lipid profiles of subjects with prostate cancer. Locoregional subjects irradiated with external beam therapy were compared to prostate cancer subjects with bone metastases. The histopathologic diagnosis of 103 subjects (71 locoregional [Group 1] and 32 palliative [Group 2]) were analyzed and compared using their blood samples, total cholesterol (CHL), triglycerides (TG), high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol...
July 1, 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/28725448/differential-prevalence-and-associations-of-overweight-and-obesity-by-gender-and-population-group-among-school-learners-in-south-africa-a-cross-sectional-study
#14
Sarah Negash, Charles Agyemang, Tandi E Matsha, Nasheeta Peer, Rajiv T Erasmus, Andre P Kengne
BACKGROUND: Factors influencing the increasing prevalence of overweight/obesity among children and adolescents in sub-Saharan Africa remain unclear. We assessed the prevalence and determinants of overweight and obesity and effects on cardio-metabolic profile in school learners in the Western Cape, South Africa. METHODS: Cross-sectional data were collected from 7 to 18-year-old South African school learners attending 14 schools, randomly selected from 107 government schools in the areas...
2017: BMC Obesity
https://www.readbyqxmd.com/read/28724475/blood-profile-and-meat-quality-of-holstein-friesian-steers-finished-on-total-mixed-ration-or-flaxseed-oil-supplemented-pellet-mixed-with-reed-canary-grass-haylage
#15
D T Utama, S G Lee, K H Baek, W S Chung, I A Chung, D I Kim, G Y Kim, S K Lee
Holstein-Friesian steer beef production is renowned globally as a secondary product of the milk industry. Grass feeding is a common practice in raising Holstein steers because of its low cost. Furthermore, grass feeding is an alternative way to produce beef with a balanced n-6 to n-3 fatty acids (FAs) ratio. However, the performance and meat quality of Holstein-Friesian cattle is more likely to depend on a high-quality diet. The aim of this study was to observe whether feeding two mixed diets; a corn-based total mixed ration (TMR) with winter ryegrass (Lolium perenne) or flaxseed oil-supplemented pellets with reed canary grass haylage (n-3 mix) provided benefits on carcass weight, meat quality and FA composition compared with cattle fed with reed canary grass (Phalaris arundinacea) haylage alone...
July 20, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28723671/qishenyiqi-pill-attenuates-atherosclerosis-by-promoting-regulatory-t-cells-inhibiting-t-helper-17-cells-and-accelerating-cholesterol-excretion
#16
Li Peng, Chong-Shan Lv, Yun Zhao, Shao-Dong Chen, Yang Huang, Da-Wei Lu, Shu-Qiong Huang, Zong-Bao Yang, Lin-Chao Qian, Lei Wen
OBJECTIVE: The aim of this study was to explore potential immunoregulatory mechanisms underlying the suppressive effect on atherosclerosis of QiShenYiQi pill (QSYQ). METHODS AND RESULTS: Male ApoE-/- mice were maintained on a Western-type diet and QSYQ treatment for eight weeks. Determination of atherosclerosis demonstrated that QSYQ attenuated plaque formation and decreased the level of blood low-density lipoproteins-cholesterol. QSYQ treatment did not affect body weight but reduced the ratio of liver weight and body weight...
July 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/28722540/association-between-serum-uric-acid-level-and-hypertension-in-a-chinese-elderly-rural-population
#17
Lei Wu, Yao He, Bin Jiang, Miao Liu, Jianhua Wang, Di Zhang, Yiyan Wang, Jing Zeng
Previous studies have examined the association between elevated serum uric acid (SUA) level and hypertension; however, the association in the Chinese elderly is still uncertain. A cross-sectional study was performed in a rural district of Beijing. A total of 2,397 participants (967 men and 1,430 women) completed the survey. The SUA levels of participants were categorized into four levels using the quartiles (P25, P50, and P75) as cutoff values. Participant was diagnosed as hyperuricemia if the SUA level was ≥417 μmol/L (male) or ≥357 μmol/L (female)...
July 19, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28722290/development-of-a-cardiovascular-diseases-risk-prediction-model-and-tools-for-chinese-patients-with-type-2-diabetes-mellitus-a-population-based-retrospective-cohort-study
#18
Eric Yuk Fai Wan, Daniel Yee Tak Fong, Colman Siu Cheung Fung, Esther Yee Tak Yu, Weng Yee Chin, Anca Ka Chun Chan, Cindy Lo Kuen Lam
AIMS: Evidence-based cardiovascular diseases(CVD) risk prediction models and tools specific for Chinese patients with type 2 diabetes mellitus(T2DM) are currently unavailable. This study aimed to develop and validate a CVD risk prediction model for Chinese T2DM patients. MATERIALS AND METHODS: A retrospective cohort study was conducted on 137 935 Chinese patients aged 18-79 years with T2DM and without prior history of CVD, who had received public primary care services between 1 January 2010 and 31 December 2010...
July 19, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28722092/-predictive-factors-of-intestinal-necrosis-in-acute-mesenteric-vascular-occlusive-diseases
#19
Dafang Liu, Yingjiang Ye, Qiwei Xie, Mujun Yin, Xiaodong Yang, Bin Liang, Shan Wang
OBJECTIVE: To explore the predictive factors of intestinal necrosis in acute mesenteric vascular occlusive diseases and its significance for the timing of exploratory laparotomy. METHODS: This retrospective study enrolled 63 patients diagnosed as acute mesenteric vascular occlusive diseases at Peking University People's Hospital between July 1995 and June 2015. Univariate analysis and multivariate logistic regression analysis were used to identify predictive factors for intestinal necrosis...
July 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28718838/phyllanthus-niruri-standardized-extract-alleviates-the-progression-of-non-alcoholic-fatty-liver-disease-and-decreases-atherosclerotic-risk-in-sprague-dawley-rats
#20
Raghdaa Hamdan Al Zarzour, Mariam Ahmad, Mohd Zaini Asmawi, Gurjeet Kaur, Mohammed Ali Ahmed Saeed, Majed Ahmed Al-Mansoub, Sultan Ayesh Mohammed Saghir, Nasiba Salisu Usman, Dhamraa W Al-Dulaimi, Mun Fei Yam
Non-alcoholic fatty liver disease (NAFLD) is one of the major global health issues, strongly correlated with insulin resistance, obesity and oxidative stress. The current study aimed to evaluate anti-NAFLD effects of three different extracts of Phyllanthus niruri (P. niruri). NAFLD was induced in male Sprague-Dawley rats using a special high-fat diet (HFD). A 50% methanolic extract (50% ME) exhibited the highest inhibitory effect against NAFLD progression. It significantly reduced hepatomegaly (16%) and visceral fat weight (22%), decreased NAFLD score, prevented fibrosis, and reduced serum total cholesterol (TC) (48%), low-density lipoprotein (LDL) (65%), free fatty acids (FFAs) (25%), alanine aminotransferase (ALT) (45%), alkaline phosphatase (ALP) (38%), insulin concentration (67%), homeostatic model assessment of insulin resistance (HOMA-IR) (73%), serum atherogenic ratios TC/high-density lipoprotein (HDL) (29%), LDL/HDL (66%) and (TC-HDL)/HDL (64%), hepatic content of cholesterol (43%), triglyceride (29%) and malondialdehyde (MDA) (40%) compared to a non-treated HFD group...
July 18, 2017: Nutrients
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