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Lipoprotein ratios

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https://www.readbyqxmd.com/read/29777805/design-of-carboxymethyl-chitosan-based-heparin-mimicking-cross-linked-beads-for-safe-and-efficient-blood-purification
#1
Yilin Wang, Xuelian Huang, Chao He, YuPei Li, Weifeng Zhao, Changsheng Zhao
Safe and efficient carboxymethyl chitosan (CMC)-based heparin-mimicking cross-linked beads (CMC/PAMPS) as adsorbents for the clearance of low-density lipoprotein-cholesterol (LDL-c) in blood purification were prepared through hydrogen bonding interactions followed with in situ cross-linking with 2-acrylamido-2-methyl-1-propanesulfonicacid (AMPS). Fourier transform infrared spectra (FTIR), two-dimensional correlation FTIR spectroscopy (2D IR), thermal gravimetric analysis (TGA) and energy dispersive X-ray spectrometer (EDS) demonstrated the successful synthesis of CMC/PAMPS beads...
May 16, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29776647/-effect-of-green-alga-ulva-lactuca-polysaccharides-supplementation-on-blood-pressure-and-on-atherogenic-risk-factors-in-rats-fed-a-high-fat-diet
#2
Z I Tair, F Bensalah, F Boukortt
AIM OF THE STUDY: To highlight the benefits of green alga Ulva lactuca polysaccharides supplementation on blood pressure and atherogenic risk factors in rats fed a high fat diet. METHODS: Wistar male rats were fed a high fat diet (30% sheep fat) for 3 months. At an average body weight (BW) of 360g, the rats (n=18) were divided into 3 groups and consumed, for 28 days, either a high fat diet (HFD) or a high fat diet enriched with 1% of whole green algae (WGA) powder or with 1% of its polysaccharides (PLS)...
May 15, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29775676/malondialdehyde-modified-ldl-related-variables-are-associated-with-diabetic-kidney-disease-in-type-2-diabetes
#3
Shoko Furukawa, Hiroaki Suzuki, Kazuya Fujihara, Kazuto Kobayashi, Hitoshi Iwasaki, Yoko Sugano, Shigeru Yatoh, Motohiro Sekiya, Naoya Yahagi, Hitoshi Shimano
BACKGROUND AND AIMS: Oxidized low-density lipoprotein (oxLDL) causes the development of atherosclerosis and kidney injury. Although circulating oxLDL levels were reportedly increased in type 2 diabetic patients with macroalbuminuria, it remains unclear whether albuminuria or the reduced glomerular filtration rate (GFR) is independently associated with the circulating oxLDL level. This study aimed to elucidate the association between the stage of diabetic nephropathy and serum malondialdehyde-modified LDL (MDA-LDL) and the ratio of MDA-LDL to LDL-cholesterol (MDA-LDL/LDL)...
May 15, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29773351/correlation-between-fibrinogen-and-white-matter-hyperintensities-among-nondiabetic-individuals-with-noncardiogenic-ischemic-stroke
#4
Cheng-Jin You, Dan Liu, Li-Li Liu, Qing-Qing Liu, Guo-Zhong Li
OBJECTIVE: The aim of the present study is to confirm the correlation between fibrinogen and the severity of cerebral white matter hyperintensities (WMHs) among nondiabetic patients with noncardiogenic acute ischemic stroke. PATIENTS AND METHODS: A cross-sectional study of 170 consecutive patients with noncardiogenic acute ischemic stroke who underwent magnetic resonance imaging and vascular imaging was conducted. WMHs were classified into periventricular hyperintensity (PVH) and deep and subcortical WMH (DSWMH) using Fazekas rating scale...
May 14, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29772482/baseline-serum-sitosterol-level-as-predictor-of-adverse-clinical-events-in-acute-coronary-syndrome-patients-with-dyslipidaemia-a-sub-analysis-of-hij-proper
#5
Junichi Yamaguchi, Erisa Kawada-Watanabe, Ryo Koyanagi, Hiroyuki Arashi, Haruki Sekiguchi, Koichi Nakao, Tetsuya Tobaru, Hiroyuki Tanaka, Toshiaki Oka, Yasuhiro Endo, Katsumi Saito, Tatsuro Uchida, Kunihiko Matsui, Hiroshi Ogawa, Nobuhisa Hagiwara
BACKGROUND AND AIMS: We aimed to examine the effect of serum sitosterol, a cholesterol absorption marker, on clinical outcomes in acute coronary syndrome patients with dyslipidaemia. METHODS: This is a sub-analysis of the HIJ-PROPER trial that assesses the effect of aggressive low-density lipoprotein cholesterol (LDL-C) lowering treatment with pitavastatin + ezetimibe in 1734 acute coronary syndrome (ACS) patients with dyslipidaemia. Patients were divided into two groups based on sitosterol level at enrolment (cut-off value was 2...
May 5, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29772479/adverse-lipid-profile-elevates-risk-for-subarachnoid-hemorrhage-a-prospective-population-based-cohort-study
#6
Joni Lindbohm, Miikka Korja, Pekka Jousilahti, Veikko Salomaa, Jaakko Kaprio
BACKGROUND AND AIMS: Studies report that both high and low total cholesterol (TC) elevates SAH risk. There are few prospective studies on high-density lipoproteins (HDL-C) and low-density lipoproteins (LDL-C), and apparently none concerns apolipoproteins A and B. We aimed to clarify the association between lipid profile and SAH risk. METHODS: The National FINRISK study provided risk-factor data recorded at enrolment between 1972 and 2007. During 1.52 million person-years of follow-up until 2014, 543 individuals suffered from incident hospitalized SAH or outside-hospital-fatal SAH...
May 5, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29770445/cost-effectiveness-of-a-community-based-diabetes-prevention-program-with-participation-incentives-for-medicaid-beneficiaries
#7
Todd Gilmer, Patrick J O'Connor, Jeffrey S Schiff, Gretchen Taylor, Gabriela Vazquez-Benitez, Joyce E Garrett, Houa Vue-Her, Sarah Rinn, Julie Anderson, Jay Desai
OBJECTIVE: To examine the cost-effectiveness of a community-based Diabetes Prevention Program (DPP) for Medicaid beneficiaries from the perspective of the health care sector. DATA SOURCES/STUDY SETTING: A total of 847 Medicaid enrollees at high risk for type 2 diabetes participating in a community-based DPP. STUDY DESIGN: Pre- and post clinical outcome and cost data were used as inputs into a validated diabetes simulation model. The model was used to evaluate quality-adjusted life years (QALYs) and health care costs over a 40-year time horizon from the perspective of the health care sector...
May 16, 2018: Health Services Research
https://www.readbyqxmd.com/read/29770124/does-family-history-of-obesity-cardiovascular-and-metabolic-diseases-influence-onset-and-severity-of-childhood-obesity
#8
Domenico Corica, Tommaso Aversa, Mariella Valenzise, Maria Francesca Messina, Angela Alibrandi, Filippo De Luca, Malgorzata Wasniewska
Objectives: The objectives were to evaluate (1) the metabolic profile and cardiometabolic risk in overweight/obese children at first assessment, stratifying patients according to severity of overweight and age; and (2) to investigate the relationship between family history (FH) for obesity and cardiometabolic diseases and severity of childhood obesity. Methods: In this cross-sectional, retrospective, observational study, 260 children (139 female), aged between 2...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29769559/elevated-plasma-lipoprotein-a-levels-were-associated-with-increased-risk-of-cardiovascular-events-in-chinese-patients-with-stable-coronary-artery-disease
#9
Wen Dai, Junke Long, Ying Cheng, Yaqin Chen, Shuiping Zhao
Recent studies have suggested that lipoprotein(a) [Lp(a)] is associated with cardiovascular disease (CVD). However, the contribution of Lp(a) to residual risk of CVD has not been determined in Chinese populations. We conducted a prospective study to evaluate the association between Lp(a) and the risk of major adverse cardiovascular events (MACEs) in patients with stable coronary artery disease (CAD) who received optimal medication treatment (OMT). The study enrolled 1602 patients with stable CAD from 5 hospitals in China...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29768597/anthropometric-changes-and-their-effects-on-cardiometabolic-risk-factors-in-rural-populations-in-brazil
#10
Tatiane Géa-Horta, Mark Anthony Beinner, Andrea Gazzinelli, Mariana Santos Felisbino Mendes, Gustavo Velasquez-Melendez
This article aims to evaluate associations between anthropometric changes in five years with lipid and blood pressure levels in Brazilian rural population. This longitudinal study evaluated 387 individuals aged 18 to 75 residents of two rural communities. Demographic, lifestyle, anthropometric, biochemical and hemodynamic characteristics were assessed in 2004 and repeated in 2009. Multivariate linear regression was used. Positive change in BMI was associated with increased diastolic blood pressure (DBP) (β = 0...
May 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29768109/effects-of-phytosterol-supplementation-on-serum-levels-of-lipid-profiles-liver-enzymes-inflammatory-markers-adiponectin-and-leptin-in-patients-affected-by-nonalcoholic-fatty-liver-disease-a-double-blind-placebo-controlled-randomized-clinical-trial
#11
Mohammad Ali Javanmardi, Majid Mohammad Shahi, Seyed Saeed Seyedian, Mohammad Hossein Haghighizadeh
OBJECTIVE: Considering the high prevalence of nonalcoholic fatty liver disease and based on the evidence about the role of dietary cholesterol in liver inflammation, and also with regard to the effect of phytosterols on the metabolism of cholesterol, we aimed at exploring the therapeutic potential of phytosterol supplementation against nonalcoholic fatty liver disease. METHOD: Thirty-eight patients with nonalcoholic fatty liver disease were randomly divided into two groups: The phytosterol group (n = 19) received a 1...
May 16, 2018: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29765163/polyunsaturated-fatty-acid-status-at-birth-childhood-growth-and-cardiometabolic-risk-a-pooled-analysis-of-the-mefab-and-rhea-cohorts
#12
Nikos Stratakis, Marij Gielen, Katerina Margetaki, Renate H M de Groot, Maria Apostolaki, Georgia Chalkiadaki, Marina Vafeiadi, Vasiliki Leventakou, Marianna Karachaliou, Roger W Godschalk, Manolis Kogevinas, Euripides G Stephanou, Maurice P Zeegers, Leda Chatzi
BACKGROUND/OBJECTIVES: Polyunsaturated fatty acid (PUFA) status during pregnancy has been suggested to influence offspring obesity and cardiometabolic health. We assessed whether prenatal PUFA exposure is associated with rapid infant growth, childhood BMI, and cardiometabolic profile. SUBJECTS/METHODS: In the Dutch MEFAB (n = 266) and Greek RHEA (n = 263) cohorts, we measured n-3 and n-6 PUFA concentrations in cord blood phospholipids, which reflect fetal exposure in late pregnancy...
May 16, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29762069/a-common-variation-in-the-caveolin-1-gene-is-associated-with-high-serum-triglycerides-and-metabolic-syndrome-in-an-admixed-latin-american-population
#13
Gustavo Mora-García, Doris Gómez-Camargo, Ángelo Alario, Claudio Gómez-Alegría
BACKGROUND: The caveolin 1 (CAV1) gene has been associated with metabolic traits in animal models and human cohorts. Recently, a prevalent variant in CAV1 has been found to be related to metabolic syndrome in Hispanics living in North America. Since Hispanics represent an admixed population at high risk for cardiovascular diseases, in this study a Latin American population with a similar genetic background was assessed. OBJECTIVE: To analyze a genetic association between CAV1 and metabolic traits in an admixed Latin American population...
May 15, 2018: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/29758349/habitual-aerobic-exercise-gene-apoa5-named-rs662799-snp-and-response-of-blood-lipid-and-lipoprotein-phenotypes-among-older-chinese-adult
#14
Xiangyun Liu, Guoyuan Huang, Zhanbin Niu, Yuqin Wei, Ru Wang
BACKGROUND: The genetic component of dyslipidemia has been studied in adults but little in older population. It is remains unknown regarding influence and interaction of APOA5 gene single nucleotide polymorphism (SNP) and habitual aerobic exercise (HAE) on changes of blood lipids and lipoprotein phenotypes in older Chinese adults. METHODS: Four-hundred-twenty-three old Chinese individuals with HAE were divided into hyperlipidemia and normal groups. We genotyped polymorphic loci using matrix assisted laser desorption ionization time of flight mass spectrometry detection technology (MALDI-TOF)...
May 11, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29757399/associations-of-dehydroepiandrosterone-sulfate-with-cardiometabolic-risk-factors-in-prepubertal-children
#15
Aino Mäntyselkä, Virpi Lindi, Anna Viitasalo, Aino-Maija Eloranta, Jyrki Ågren, Sari Väisänen, Raimo Voutilainen, Tomi Laitinen, Timo A Lakka, Jarmo Jääskeläinen
Context: Premature adrenarche (PA) has been associated with overweight and insulin resistance, but the associations of serum dehydroepiandrosterone sulfate (DHEAS) concentration with other cardiometabolic risk factors are uncertain. Objective: To examine the associations of serum DHEAS concentration with several cardiometabolic risk factors in children. Design: Cross-sectional data from the Physical Activity and Nutrition in Children Study...
May 10, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29754570/cardiovascular-risk-factors-in-a-child-population-the-health-oriented-pedagogical-project-hopp
#16
Wei Hai Deng, Morten Lindberg, Ole Petter Hjelle, Asgeir Mamen, Per Morten Fredriksen
AIMS: The main aim of the present study was to investigate the clustering of risk factors for cardiovascular diseases and metabolic syndrome in a large, healthy representative Norwegian child population. METHODS: From a population of 2817, parents of 2297 children agreed to participate. Values of waist circumference (WC), total cholesterol (TC), high-density lipoprotein (HDL), systolic blood pressure (sysBP), haemoglobin-A1c (HbA1c) and Andersen aerobic fitness test were used to test clustering of cardiometabolic risk factors in this sample...
May 2018: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/29754072/serum-betatrophin-angiopoietin-like-protein-8-angptl8-levels-in-pregnancies-affected-by-hyperemesis-gravidarum
#17
Burcu Timur, Serap Fırtına Tuncer, Serkan Bodur, Hakan Timur, Aytekin Tokmak, Funda Gucel, Metin Altay
OBJECTIVE: The association between serum betatrophin levels and hyperemesis gravidarum (HEG) remains unknown. The aim of this study was to determine and understand the alterations in serum betatrophin levels in pregnancies complicated by HEG compared with unaffected normal pregnancies. STUDY DESIGN: A cohort study was carried out to evaluate serum betatrophin levels in patients with HEG. Serum betatrophin concentrations were measured with other metabolic markers for lipids and glucose metabolism in 40 singleton pregnancies affected by HEG and 40 gestational age- and body mass index-matched controls...
April 24, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29753426/-sardine-purified-proteins-improve-blood-pressure-glycemic-control-anti-atherogenic-metabolic-pathways-and-antioxidant-capacity-in-obese-rats
#18
F Affane, F Bensalah, N I Harrat, H Chekkal, S Louala, M Y Lamri-Senhadji
AIM OF THE STUDY: The effects of sardine by-products (SBy-P) and fillet proteins (SF-P) were compared to casein (Cas) ; these effects were assessed on blood pressure, glycemic control, reverse cholesterol transport, lipid peroxidation and total antioxidant capacity in obese rats. MATERIALS AND METHODS: Eighteen male Wistar rats were subjected for three months, to a high-fat diet. The obese rats were divided into three groups and consumed the same high-fat diet for 28 days after addition of either, 20% SBy-P, SF-P or Cas...
May 9, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29752998/effect-of-protein-intake-beyond-habitual-intakes-following-resistance-training-on-cardiometabolic-risk-disease-parameters-in-pre-conditioned-older-women
#19
Rodrigo R Fernandes, Hellen C G Nabuco, Paulo Sugihara Junior, Edilaine F Cavalcanti, Crisieli M Tomeleri, Alex S Ribeiro, Décio S Barbosa, Danielle Venturini, Brad J Schoenfeld, Edilson S Cyrino
OBJECTIVE: The aim of this study was to analyze the effects of higher protein (HP) intake associated with resistance training (RT) on parameters of cardiometabolic risk disease (CMR). METHODS: A randomized, double-blind and placebo-controlled design was conducted. Thirty-two pre-conditioned older women were randomized in two groups to receive 35 g of protein (high protein group - HP) or 35 g of placebo (low protein group - LP) after training sessions. The RT program was carried out over 12 weeks, 3 days per week and 3 sets of 8-12 repetitions...
May 9, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29751766/changes-in-lipid-indices-and-body-composition-one-year-after-laparoscopic-gastrectomy-a-prospective-study
#20
Soo Jin Lee, Ji Young Kim, Tae Kyung Ha, Yun Young Choi
BACKGROUND: The purpose of this prospective study was to investigate changes in lipid indices associated with whole body composition during 1 year of follow-up after laparoscopic gastrectomy. METHODS: Thirty-seven patients with benign and malignant gastric neoplasm who underwent laparoscopic gastrectomy were prospectively enrolled. None of the patients were treated with adjuvant chemotherapy. Lipid indices and body composition were measured preoperatively and at six and 12 months after laparoscopic gastrectomy...
May 11, 2018: Lipids in Health and Disease
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