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Dual energy mammography

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https://www.readbyqxmd.com/read/27853496/a-case-of-a-concurrent-and-co-located-invasive-carcinoma-and-a-fibroadenoma-to-illustrate-the-potential-of-dual-energy-contrast-enhanced-digital-mammography-on-the-diagnosis-of-complex-breast-lesions
#1
Maria Del Mar Travieso Aja, Purificacion Munoz, Mario Rodriguez Rodriguez, Victor Vega Benitez, Octavio P Luzardo
Up to 19% of breast malignancies may be missed by conventional imaging techniques, especially when they are concurrent or co-located with other benign lesions. However, more sensitive techniques, such as magnetic resonance imaging (MRI), are often too expensive for routine use in developing countries. Contrast-enhanced, dual-energy digital mammography (CESM) is a recently introduced imaging modality whose performance has been reported to be similar to that of MRI. Being much cheaper, CESM may constitute a good alternative for improving diagnostic sensitivity in these countries...
July 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27782705/quantification-of-breast-lesion-compositions-using-low-dose-spectral-mammography-a-feasibility-study
#2
Huanjun Ding, David Sennung, Hyo-Min Cho, Sabee Molloi
PURPOSE: The positive predictive power for malignancy can potentially be improved, if the chemical compositions of suspicious breast lesions can be reliably measured in screening mammography. The purpose of this study is to investigate the feasibility of quantifying breast lesion composition, in terms of water and lipid contents, with spectral mammography. METHODS: Phantom and tissue samples were imaged with a spectral mammography system based on silicon-strip photon-counting detectors...
October 2016: Medical Physics
https://www.readbyqxmd.com/read/27768681/degree-of-enhancement-on-contrast-enhanced-spectral-mammography-cesm-and-lesion-type-on-mammography-mg-comparison-based-on-histological-results
#3
Elżbieta Łuczyńska, Joanna Niemiec, Edward Hendrick, Sylwia Heinze, Janusz Jaszczyński, Jerzy Jakubowicz, Beata Sas-Korczyńska, Janusz Rys
BACKGROUND Contrast enhanced spectral mammography (CESM) is a new method of breast cancer diagnosis in which an iodinated contrast agent is injected and dual-energy mammography is obtained in multiple views of the breasts. The aim of this study was to compare the degree of enhancement on CESM with lesion characteristics on mammography (MG) and lesion histology in women with suspicious breast lesions. MATERIAL AND METHODS The degree of enhancement on CESM (absent, weak, medium, or strong) was compared to lesion characteristics on MG (mass, mass with microcalcifications, or microcalcifications alone) and histology (infiltrating carcinoma, intraductal carcinoma, or benign) to compare sensitivity of the two modalities and to establish correlations that might improve diagnostic accuracy...
October 21, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27611215/dual-energy-contrast-enhanced-spectral-mammography-enhancement-analysis-on-bi-rads-4-non-mass-microcalcifications-in-screened-women
#4
Yun-Chung Cheung, Yu-Hsiang Juan, Yu-Ching Lin, Yung-Feng Lo, Hsiu-Pei Tsai, Shir-Hwa Ueng, Shin-Cheh Chen
BACKGROUND: Mammography screening is a cost-efficient modality with high sensitivity for detecting impalpable cancer with microcalcifications, and results in reduced mortality rates. However, the probability of finding microcalcifications without associated cancerous masses varies. We retrospectively evaluated the diagnosis and cancer probability of the non-mass screened microcalcifications by dual-energy contrast-enhanced spectral mammography (DE-CESM). PATIENTS AND METHODS: With ethical approval from our hospital, we enrolled the cases of DE-CESM for analysis under the following inclusion criteria: (1) referrals due to screened BI-RADS 4 microcalcifications; (2) having DE-CESM prior to stereotactic biopsy; (3) no associated mass found by sonography and physical examination; and (4) pathology-based diagnosis using stereotactic vacuum-assisted breast biopsy...
2016: PloS One
https://www.readbyqxmd.com/read/27452266/adding-the-power-of-contrast-to-the-credibility-of-mammography-in-breast-cancer-diagnosis
#5
Alexandra Tsigginou, Christina Gkali, Athanasios Chalazonitis, Eleni Feida, Dimitrios Efthymios Vlachos, Flora Zagouri, Ioannis Rellias, Constantine Dimitrakakis
OBJECTIVE: Despite advancements in technology, mammography remains the golden standard in breast cancer diagnosis and in mortality reduction. Overtime, digital mammography combined with other imaging modalities supported a trend to more accurately presume pathological diagnosis. Dual-energy Contrast Enhanced Spectral Mammography (CESM) represents a relatively new diagnostic tool adjunct to mammography. The aim of this study is to strengthen the BIRADS classification score in order to improve early breast cancer diagnosis...
July 25, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27412458/gold-silver-alloy-nanoparticles-gsan-an-imaging-probe-for-breast-cancer-screening-with-dual-energy-mammography-or-computed-tomography
#6
Pratap C Naha, Kristen C Lau, Jessica C Hsu, Maryam Hajfathalian, Shaameen Mian, Peter Chhour, Lahari Uppuluri, Elizabeth S McDonald, Andrew D A Maidment, David P Cormode
Earlier detection of breast cancer reduces mortality from this disease. As a result, the development of better screening techniques is a topic of intense interest. Contrast-enhanced dual-energy mammography (DEM) is a novel technique that has improved sensitivity for cancer detection. However, the development of contrast agents for this technique is in its infancy. We herein report gold-silver alloy nanoparticles (GSAN) that have potent DEM contrast properties and improved biocompatibility. GSAN formulations containing a range of gold : silver ratios and capped with m-PEG were synthesized and characterized using various analytical methods...
July 14, 2016: Nanoscale
https://www.readbyqxmd.com/read/27376457/clinical-study-of-contrast-enhanced-digital-mammography-and-the-evaluation-of-blood-and-lymphatic-microvessel-density
#7
María-Ester Brandan, Juan P Cruz-Bastida, Iván M Rosado-Méndez, Yolanda Villaseñor-Navarro, Héctor Pérez-Ponce, Héctor A Galván, Flavio E Trujillo-Zamudio, Patricia Sánchez-Suárez, Luis Benítez-Bribiesca
OBJECTIVE: To correlate image parameters in contrast-enhanced digital mammography (CEDM) with blood and lymphatic microvessel density (MVD). METHODS: 18 Breast Imaging-Reporting and Data System (BI-RADS)-4 to BI-RADS-5 patients were subjected to CEDM. Craniocaudal views were acquired, two views (low and high energy) before iodine contrast medium (CM) injection and four views (high energy) 1-5 min afterwards. Processing included registration and two subtraction modalities, traditional single-energy temporal (high-energy) and "dual-energy temporal with a matrix", proposed to improve lesion conspicuity...
September 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27277055/a-novel-approach-to-background-subtraction-in-contrast-enhanced-dual-energy-digital-mammography-with-commercially-available-mammography-devices-noise-minimization
#8
Adriano Contillo, Giovanni Di Domenico, Paolo Cardarelli, Mauro Gambaccini, Angelo Taibi
PURPOSE: Dual-energy image subtraction represents a useful tool to improve the detectability of small lesions, especially in dense breasts. A feature it shares with all x-ray imaging techniques is the appearance of fluctuations in the texture of the background, which can obscure the visibility of interesting details. The aim of the work is to investigate the main noise sources, in order to create a better performing subtraction mechanism. In particular, the structural noise cancellation was achieved by means of a suitable extension of the dual-energy algorithm...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/26921822/digital-x-ray-radiogrammetry-in-the-study-of-osteoporotic-fractures-comparison-to-dual-energy-x-ray-absorptiometry-and-frax
#9
Johan Kälvesten, Li-Yung Lui, Torkel Brismar, Steven Cummings
Osteoporosis is often underdiagnosed and undertreated. Screening of post-menopausal women for clinical risk factors and/or low bone mineral density (BMD) has been proposed to overcome this. Digital X-ray radiogrammetry (DXR) estimates hand BMD from standard hand X-ray images and have shown to predict fractures and osteoporosis. Recently, digital radiology and the internet have opened up the possibility of conducting automated opportunistic screening with DXR in post-fracture care or in combination with mammography...
May 2016: Bone
https://www.readbyqxmd.com/read/26910906/development-of-silica-encapsulated-silver-nanoparticles-as-contrast-agents-intended-for-dual-energy-mammography
#10
Roshan Karunamuni, Pratap C Naha, Kristen C Lau, Ajlan Al-Zaki, Anatoliy V Popov, Edward J Delikatny, Andrew Tsourkas, David P Cormode, Andrew D A Maidment
OBJECTIVE: Dual-energy (DE) mammography has recently entered the clinic. Previous theoretical and phantom studies demonstrated that silver provides greater contrast than iodine for this technique. Our objective was to characterize and evaluate in vivo a prototype silver contrast agent ultimately intended for DE mammography. METHODS: The prototype silver contrast agent was synthesized using a three-step process: synthesis of a silver core, silica encapsulation and PEG coating...
September 2016: European Radiology
https://www.readbyqxmd.com/read/26520754/a-novel-approach-to-background-subtraction-in-contrast-enhanced-dual-energy-digital-mammography-with-commercially-available-mammography-devices-polychromaticity-correction
#11
Adriano Contillo, Giovanni Di Domenico, Paolo Cardarelli, Mauro Gambaccini, Angelo Taibi
PURPOSE: Contrast-enhanced digital mammography is an image subtraction technique that is able to improve the detectability of lesions in dense breasts. One of the main sources of error, when the technique is performed by means of commercial mammography devices, is represented by the intrinsic polychromaticity of the x-ray beams. The aim of the work is to propose an iterative procedure, which only assumes the knowledge of a small set of universal quantities, to take into account the polychromaticity and correct the subtraction results accordingly...
November 2015: Medical Physics
https://www.readbyqxmd.com/read/26373754/contrast-enhanced-dual-energy-mammography-with-a-novel-anode-filter-combination-and-artifact-reduction-a-feasibility-study
#12
Thomas Knogler, Peter Homolka, Mathias Hörnig, Robert Leithner, Georg Langs, Martin Waitzbauer, Katja Pinker-Domenig, Sabine Leitner, Thomas H Helbich
OBJECTIVES: To demonstrate the feasibility of contrast-enhanced dual-energy mammography (CEDEM) using titanium (Ti) filtering at 49 kVp for high-energy images and a novel artefact reducing image-subtraction post-processing algorithm. METHODS: Fifteen patients with suspicious findings (ACR BI-RADS 4 and 5) detected with digital mammography (MG) that required biopsy were included. CEDEM examinations were performed on a modified prototype machine. Acquired HE and low-energy raw data images were registered non-rigidly to compensate for possible subtle tissue motion...
June 2016: European Radiology
https://www.readbyqxmd.com/read/26203367/characterization-of-structural-prior-guided-optical-tomography-using-realistic-breast-models-derived-from-dual-energy-x-ray-mammography
#13
Bin Deng, Dana H Brooks, David A Boas, Mats Lundqvist, Qianqian Fang
Multi-spectral near-infrared diffuse optical tomography (DOT) is capable of providing functional tissue assessment that can complement structural mammographic images for more comprehensive breast cancer diagnosis. To take full advantage of the readily available sub-millimeter resolution structural information in a multi-modal imaging setting, an efficient x-ray/optical joint image reconstruction model has been proposed previously to utilize anatomical information from a mammogram as a structural prior. In this work, we develop a complex digital breast phantom (available at http://openjd...
July 1, 2015: Biomedical Optics Express
https://www.readbyqxmd.com/read/26159872/clinical-utility-of-dual-energy-contrast-enhanced-spectral-mammography-for-breast-microcalcifications-without-associated-mass-a-preliminary-analysis
#14
Yun-Chung Cheung, Hsiu-Pei Tsai, Yung-Feng Lo, Shir-Hwa Ueng, Pei-Chin Huang, Shin-Chih Chen
OBJECTIVE: To assess the utility of dual-energy contrast-enhanced spectral mammography (DE-CESM) for evaluation of suspicious malignant microcalcifications. METHODS: Two hundred and fifty-six DE-CESMs were reviewed from 2012-2013, 59 cases fulfilled the following criteria and were enrolled for analysis: (1) suspicious malignant microcalcifications (BI-RADS 4) on mammogram, (2) no related mass, (3) with pathological diagnoses. The microcalcification morphology and associated enhancement were reviewed to analyse the accuracy of the diagnosis and cancer size measurements versus the results of pathology...
April 2016: European Radiology
https://www.readbyqxmd.com/read/26129008/tu-ef-207-01-introductory-remarks-on-recent-advances-in-breast-imaging
#15
A Karellas
UNLABELLED: Breast imaging technology is advancing on several fronts. In digital mammography, the major technological trend has been on optimization of approaches for performing combined mammography and tomosynthesis using the same system. In parallel, photon-counting slot-scan mammography is now in clinical use and more efforts are directed towards further development of this approach for spectral imaging. Spectral imaging refers to simultaneous acquisition of two or more energy-windowed images...
June 2015: Medical Physics
https://www.readbyqxmd.com/read/26129007/tu-ef-207-04-advances-in-detector-technology-for-breast-tomosynthesis
#16
W Zhao
UNLABELLED: Breast imaging technology is advancing on several fronts. In digital mammography, the major technological trend has been on optimization of approaches for performing combined mammography and tomosynthesis using the same system. In parallel, photon-counting slot-scan mammography is now in clinical use and more efforts are directed towards further development of this approach for spectral imaging. Spectral imaging refers to simultaneous acquisition of two or more energy-windowed images...
June 2015: Medical Physics
https://www.readbyqxmd.com/read/26129005/tu-ef-207-00-advances-in-breast-imaging
#17
(no author information available yet)
UNLABELLED: Breast imaging technology is advancing on several fronts. In digital mammography, the major technological trend has been on optimization of approaches for performing combined mammography and tomosynthesis using the same system. In parallel, photon-counting slot-scan mammography is now in clinical use and more efforts are directed towards further development of this approach for spectral imaging. Spectral imaging refers to simultaneous acquisition of two or more energy-windowed images...
June 2015: Medical Physics
https://www.readbyqxmd.com/read/26129004/tu-ef-207-05-dedicated-cone-beam-breast-ct
#18
S Vedantham
UNLABELLED: Breast imaging technology is advancing on several fronts. In digital mammography, the major technological trend has been on optimization of approaches for performing combined mammography and tomosynthesis using the same system. In parallel, photon-counting slot-scan mammography is now in clinical use and more efforts are directed towards further development of this approach for spectral imaging. Spectral imaging refers to simultaneous acquisition of two or more energy-windowed images...
June 2015: Medical Physics
https://www.readbyqxmd.com/read/26129000/tu-ef-207-02-spectral-mammography-based-on-photon-counting-detectors
#19
S Molloi
UNLABELLED: Breast imaging technology is advancing on several fronts. In digital mammography, the major technological trend has been on optimization of approaches for performing combined mammography and tomosynthesis using the same system. In parallel, photon-counting slot-scan mammography is now in clinical use and more efforts are directed towards further development of this approach for spectral imaging. Spectral imaging refers to simultaneous acquisition of two or more energy-windowed images...
June 2015: Medical Physics
https://www.readbyqxmd.com/read/26128999/tu-ef-207-03-advances-in-stationary-breast-tomosynthesis-using-distributed-x-ray-sources
#20
O Zhou
UNLABELLED: Breast imaging technology is advancing on several fronts. In digital mammography, the major technological trend has been on optimization of approaches for performing combined mammography and tomosynthesis using the same system. In parallel, photon-counting slot-scan mammography is now in clinical use and more efforts are directed towards further development of this approach for spectral imaging. Spectral imaging refers to simultaneous acquisition of two or more energy-windowed images...
June 2015: Medical Physics
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