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Spectral mammography

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https://www.readbyqxmd.com/read/28226399/wavelet-based-scaling-indices-for-breast-cancer-diagnostics
#1
T Roberts, M Newell, W Auffermann, B Vidakovic
Mammography is routinely used to screen for breast cancer. However, the radiological interpretation of mammogram images is complicated by the heterogeneous nature of normal breast tissue and the fact that cancers are often of the same radiographic density as normal tissue. In this work, we use wavelets to quantify spectral slopes of breast cancer cases and controls and demonstrate their value in classifying images. In addition, we propose asymmetry statistics to be used in forming features, which improve the classification result...
February 22, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28112559/breast-radiation-dose-with-cesm-compared-with-2d-ffdm-and-3d-tomosynthesis-mammography
#2
COMPARATIVE STUDY
Judy R James, William Pavlicek, James A Hanson, Thomas F Boltz, Bhavika K Patel
OBJECTIVE: We aimed to compare radiation dose received during contrast-enhanced spectral mammography (CESM) using high- and low-energy projections with radiation dose received during 2D full field digital mammography (FFDM) and 3D tomosynthesis on phantoms and patients with varying breast thickness and density. MATERIALS AND METHODS: A single left craniocaudal projection was chosen to determine the doses for 6214 patients who underwent 2D FFDM, 3662 patients who underwent 3D tomosynthesis, and 173 patients who underwent CESM in this retrospective study...
February 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28107737/contrast-enhanced-spectral-mammography-cesm-versus-mri-in-the-high-risk-screening-setting-patient-preferences-and-attitudes
#3
Jordana Phillips, Matthew M Miller, Tejas S Mehta, Valerie Fein-Zachary, Audrey Nathanson, Wendy Hori, Rita Monahan-Earley, Priscilla J Slanetz
PURPOSE: Our study evaluates patient preferences toward screening CESM versus MRI. MATERIALS AND METHODS: As part of a prospective study, high-risk patients had breast MRI and CESM. Patients completed an anonymous survey to evaluate preferences regarding the two modalities. RESULTS: 88% of participants completed the survey. 79% preferred CESM over MRI if the exams had equal sensitivity. 89% would be comfortable receiving contrast as part of an annual screening test...
March 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28094850/discriminating-solitary-cysts-from-soft-tissue-lesions-in-mammography-using-a-pretrained-deep-convolutional-neural-network
#4
Thijs Kooi, Bram van Ginneken, Nico Karssemeijer, Ard den Heeten
PURPOSE: It is estimated that 7% of women in the western world will develop palpable breast cysts in their lifetime. Even though cysts have been correlated with risk of developing breast cancer, many of them are benign and do not require follow-up. We develop a method to discriminate benign solitary cysts from malignant masses in digital mammography. We think a system like this can have merit in the clinic as a decision aid or complementary to specialised modalities. METHODS: We employ a deep Convolutional Neural Network (CNN) to classify cyst and mass patches...
January 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28055247/staging-of-breast-cancer-and-the-advanced-applications-of-digital-mammogram-what-the-physician-needs-to-know
#5
Maha H Helal, Sahar M Mansour, Mai Zaglol, Lamia A Salaleldin, Omniya M Nada, Marwa A Haggag
OBJECTIVE: To study the role of advanced applications of digital mammogram, whether contrast-enhanced spectral mammography (CESM) or digital breast tomosynthesis (DBT), in the "T" staging of histologically proven breast cancer before planning for treatment management. METHODS: In this prospective analysis, we evaluated 98 proved malignant breast masses regarding their size, multiplicity and the presence of associated clusters of microcalcifications. Evaluation methods included digital mammography (DM), 3D tomosynthesis and CESM...
February 22, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28047752/we-de-207b-04-quantitative-contrast-enhanced-spectral-mammography-based-on-photon-counting-detectors-a-feasibility-study
#6
H Ding, B Zhou, D Beidokhti, S Molloi
PURPOSE: To investigate the feasibility of accurate quantification of iodine mass thickness in contrast-enhanced spectral mammography. METHODS: Experimental phantom studies were performed on a spectral mammography system based on Si strip photon-counting detectors. Dual-energy images were acquired using 40 kVp and a splitting energy of 34 keV with 3 mm Al pre-filtration. The initial calibration was done with glandular and adipose tissue equivalent phantoms of uniform thicknesses and iodine disk phantoms of various concentrations...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047365/mo-fg-campus-iep1-01-alternative-k-edge-filters-for-low-energy-image-acquisition-in-contrast-enhanced-spectral-mammography
#7
S Shrestha, S Vedantham, A Karellas
PURPOSE: In Contrast Enhanced Spectral Mammography (CESM), Rh filter is often used during low-energy image acquisition. The potential for using Ag, In and Sn filters, which exhibit K-edge closer to, and just below that of Iodine, instead of the Rh filter, was investigated for the low-energy image acquisition. METHODS: Analytical computations of the half-value thickness (HVT) and the photon fluence per mAs (photons/mm2/mAs) for 50µm Rh were compared with other potential K-edge filters (Ag, In and Sn), all with K-absorption edge below that of Iodine...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047254/tu-d-209-01-dosimetry-of-diagnostic-work-up-mammography
#8
N Jallow, I Sechopoulos
PURPOSE: To investigate patient average glandular dose (AGD) characteristics of diagnostic mammography. METHODS: The techniques used to image 14420 patients who received diagnostic work up mammography from October 2008 to December 2014 at one academic hospital were retrospectively collected. The most common diagnostic views and the techniques used for each according to compressed breast thickness were determined. For all techniques, 1st half value layer and air kerma output per tube current-exposure time product were measured; then the incident air kerma for each acquisition was calculated...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046981/we-de-207b-01-optimization-for-contrast-enhanced-spectral-mammography-based-on-photon-counting-detectors
#9
H Ding, S Molloi
PURPOSE: To investigate the feasibility of optimizing the imaging parameters for contrast-enhanced spectral mammography based on Si strip photon-counting detectors. METHODS: A computer simulation model using polyenergetic spectra from a tungsten anode x-ray tube and a Si-based photon-counting detector was evaluated for contrast-enhanced spectral mammography. The simulation traces the emission of photons from the x-ray source, attenuation through the breast and subsequent absorption in the detector...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046738/su-f-i-53-coded-aperture-coherent-scatter-spectral-imaging-of-the-breast-a-monte-carlo-evaluation-of-absorbed-dose
#10
R Morris, M Lakshmanan, G Fong, A Kapadia, J Greenberg
PURPOSE: Coherent scatter based imaging has shown improved contrast and molecular specificity over conventional digital mammography however the biological risks have not been quantified due to a lack of accurate information on absorbed dose. This study intends to characterize the dose distribution and average glandular dose from coded aperture coherent scatter spectral imaging of the breast. The dose deposited in the breast from this new diagnostic imaging modality has not yet been quantitatively evaluated...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046698/mo-fg-campus-iep1-02-dose-reduction-in-contrast-enhanced-digital-mammography-using-a-photon-counting-detector
#11
S Lee, S Kang, J Eom
PURPOSE: Photon-counting detectors (PCDs) allow multi-energy X-ray imaging without additional exposures and spectral overlap. This capability results in the improvement of accuracy of material decomposition for dual-energy X-ray imaging and the reduction of radiation dose. In this study, the PCD-based contrast-enhanced dual-energy mammography (CEDM) was compared with the conventional CDEM in terms of radiation dose, image quality and accuracy of material decomposition. METHODS: A dual-energy model was designed by using Beer-Lambert's law and rational inverse fitting function for decomposing materials from a polychromatic X-ray source...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27896471/contrast-enhanced-spectral-mammography-vs-mammography-and-mri-clinical-performance-in-a-multi-reader-evaluation
#12
Eva M Fallenberg, Florian F Schmitzberger, Heba Amer, Barbara Ingold-Heppner, Corinne Balleyguier, Felix Diekmann, Florian Engelken, Ritse M Mann, Diane M Renz, Ulrich Bick, Bernd Hamm, Clarisse Dromain
OBJECTIVES: To compare the diagnostic performance of contrast-enhanced spectral mammography (CESM) to digital mammography (MG) and magnetic resonance imaging (MRI) in a prospective two-centre, multi-reader study. METHODS: One hundred seventy-eight women (mean age 53 years) with invasive breast cancer and/or DCIS were included after ethics board approval. MG, CESM and CESM + MG were evaluated by three blinded radiologists based on amended ACR BI-RADS criteria...
November 28, 2016: European Radiology
https://www.readbyqxmd.com/read/27854006/mammography-an-update-of-the-eusobi-recommendations-on-information-for-women
#13
Francesco Sardanelli, Eva M Fallenberg, Paola Clauser, Rubina M Trimboli, Julia Camps-Herrero, Thomas H Helbich, Gabor Forrai
: This article summarises the information to be offered to women about mammography. After a delineation of the aim of early diagnosis of breast cancer, the difference between screening mammography and diagnostic mammography is explained. The need to bring images and reports from the previous mammogram (and from other recent breast imaging examinations) is highlighted. Mammography technique and procedure are described with particular attention to discomfort and pain experienced by a small number of women who undergo the test...
February 2017: Insights Into Imaging
https://www.readbyqxmd.com/read/27782705/quantification-of-breast-lesion-compositions-using-low-dose-spectral-mammography-a-feasibility-study
#14
Huanjun Ding, David Sennung, Hyo-Min Cho, Sabee Molloi
PURPOSE: The positive predictive power for malignancy can potentially be improved, if the chemical compositions of suspicious breast lesions can be reliably measured in screening mammography. The purpose of this study is to investigate the feasibility of quantifying breast lesion composition, in terms of water and lipid contents, with spectral mammography. METHODS: Phantom and tissue samples were imaged with a spectral mammography system based on silicon-strip photon-counting detectors...
October 2016: Medical Physics
https://www.readbyqxmd.com/read/27773458/contrast-enhanced-spectral-mammography-technique-indications-and-clinical-applications
#15
Chandni Bhimani, Danielle Matta, Robyn G Roth, Lydia Liao, Elizabeth Tinney, Kristin Brill, Pauline Germaine
RATIONALE AND OBJECTIVES: Contrast-enhanced spectral mammography (CESM) combines the benefits of full field digital mammography with the concept of tumor angiogenesis. Technique and practical applications of CESM are discussed. MATERIALS AND METHODS: An overview of the technique is followed by a demonstration of practical applications of CESM in our practice. RESULTS: We have successfully implemented CESM into our practice as a screening, diagnostic, staging, and treatment response tool...
January 2017: Academic Radiology
https://www.readbyqxmd.com/read/27768681/degree-of-enhancement-on-contrast-enhanced-spectral-mammography-cesm-and-lesion-type-on-mammography-mg-comparison-based-on-histological-results
#16
Elżbieta Łuczyńska, Joanna Niemiec, Edward Hendrick, Sylwia Heinze, Janusz Jaszczyński, Jerzy Jakubowicz, Beata Sas-Korczyńska, Janusz Rys
BACKGROUND Contrast enhanced spectral mammography (CESM) is a new method of breast cancer diagnosis in which an iodinated contrast agent is injected and dual-energy mammography is obtained in multiple views of the breasts. The aim of this study was to compare the degree of enhancement on CESM with lesion characteristics on mammography (MG) and lesion histology in women with suspicious breast lesions. MATERIAL AND METHODS The degree of enhancement on CESM (absent, weak, medium, or strong) was compared to lesion characteristics on MG (mass, mass with microcalcifications, or microcalcifications alone) and histology (infiltrating carcinoma, intraductal carcinoma, or benign) to compare sensitivity of the two modalities and to establish correlations that might improve diagnostic accuracy...
October 21, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27765597/contrast-enhanced-spectral-mammography-modality-specific-artifacts-and-other-factors-which-may-interfere-with-image-quality
#17
Chandni Bhimani, Luna Li, Lydia Liao, Robyn G Roth, Elizabeth Tinney, Pauline Germaine
RATIONALE AND OBJECTIVES: Contrast-enhanced spectral mammography (CESM) uses full field digital mammography with the added benefit of intravenous contrast administration to significantly reduce false-positive and false-negative results and improve specificity while maintaining high sensitivity. For CESM to fulfill its purpose, one should be aware of possible artifacts and other factors which may interfere with image quality, and attention should be taken to minimize these factors. MATERIALS AND METHODS: This pictorial demonstration will depict types of artifacts detected and other factors that interfere with image acquisition in our practice since CESM implementation...
January 2017: Academic Radiology
https://www.readbyqxmd.com/read/27687829/contrast-enhanced-spectral-mammography-cesm-versus-breast-magnetic-resonance-imaging-mri-a-retrospective-comparison-in-66-breast-lesions
#18
L Li, R Roth, P Germaine, S Ren, M Lee, K Hunter, E Tinney, L Liao
OBJECTIVE: The purpose of this study was to retrospectively compare the diagnostic performance of contrast-enhanced spectral mammography (CESM) with that of breast magnetic resonance imaging (BMRI) in breast cancer detection using parameters, including sensitivity, positive predictive value (PPV), lesion size, morphology, lesion and background enhancement, and examination time. MATERIALS AND METHODS: A total of 48 women (mean age, 56years±10.6 [SD]) with breast lesions detected between October 2012 and March 2014 were included...
September 26, 2016: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/27611215/dual-energy-contrast-enhanced-spectral-mammography-enhancement-analysis-on-bi-rads-4-non-mass-microcalcifications-in-screened-women
#19
Yun-Chung Cheung, Yu-Hsiang Juan, Yu-Ching Lin, Yung-Feng Lo, Hsiu-Pei Tsai, Shir-Hwa Ueng, Shin-Cheh Chen
BACKGROUND: Mammography screening is a cost-efficient modality with high sensitivity for detecting impalpable cancer with microcalcifications, and results in reduced mortality rates. However, the probability of finding microcalcifications without associated cancerous masses varies. We retrospectively evaluated the diagnosis and cancer probability of the non-mass screened microcalcifications by dual-energy contrast-enhanced spectral mammography (DE-CESM). PATIENTS AND METHODS: With ethical approval from our hospital, we enrolled the cases of DE-CESM for analysis under the following inclusion criteria: (1) referrals due to screened BI-RADS 4 microcalcifications; (2) having DE-CESM prior to stereotactic biopsy; (3) no associated mass found by sonography and physical examination; and (4) pathology-based diagnosis using stereotactic vacuum-assisted breast biopsy...
2016: PloS One
https://www.readbyqxmd.com/read/27600118/-diagnostic-imaging-of-breast-cancer-an-update
#20
M Funke
Advances in imaging of the female breast have substantially influenced the diagnosis and probably also the therapy and prognosis of breast cancer in the past few years. This article gives an overview of the most important imaging modalities in the diagnosis of breast cancer. Digital mammography is considered to be the gold standard for the early detection of breast cancer. Digital breast tomosynthesis can increase the diagnostic accuracy of mammography and is used for the assessment of equivocal or suspicious mammography findings...
October 2016: Der Radiologe
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