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Spectral mammography

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https://www.readbyqxmd.com/read/29727287/direct-regularization-from-co-registered-contrast-mri-improves-image-quality-of-mri-guided-near-infrared-spectral-tomography-of-breast-lesions
#1
Limin Zhang, Shudong Jiang, Yan Zhao, Jinchao Feng, Brian W Pogue, Keith D Paulsen
An approach using direct regularization from co-registered dynamic contrast enhanced magnetic reson- ance images was used to reconstruct near-infrared spectral tomography patient images, which does not need image segmentation. 20 patients with mammography/ultrasound confirmed breast abnormalities were involved in this paper, and the resulting images indicated that tumor total hemoglobin concentration contrast differentiated malignant from benign cases (p-value = 0.021). The approach prod- uced reconstructed images, which significantly reduced surface artifacts near the source-detector locations (p-value = 4...
May 2018: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/29606631/workflow-considerations-for-incorporation-of-contrast-enhanced-spectral-mammography-into-a-breast-imaging-practice
#2
Jordana Phillips, Jennifer Steinkeler, Komal Talati, Alexander Brook, Vandana Dialani, Michael Fishman, Priscilla J Slanetz, Tejas S Mehta
No abstract text is available yet for this article.
March 30, 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29516362/contrast-enhanced-spectral-mammography-is-comparable-to-mri-in-the-assessment-of-residual-breast-cancer-following-neoadjuvant-systemic-therapy
#3
Bhavika K Patel, Talal Hilal, Matthew Covington, Nan Zhang, Heidi E Kosiorek, Marc Lobbes, Donald W Northfelt, Barbara A Pockaj
PURPOSE: To evaluate the performance of contrast-enhanced spectral mammography (CESM) compared to MRI in the assessment of tumor response in breast cancer patients undergoing neoadjuvant systemic therapy (NST). METHODS: The institutional review board approved this study. From September 2014 to June 2017, we identified patients with pathologically confirmed invasive breast cancer who underwent NST. All patients had both CESM and MRI performed pre- and post-NST with pathological assessment after surgical management...
May 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29451413/quantitative-analysis-of-enhanced-malignant-and-benign-lesions-on-contrast-enhanced-spectral-mammography
#4
Chih-Ying Deng, Yu-Hsiang Juan, Yun-Chung Cheung, Yu-Ching Lin, Yung-Feng Lo, GiGin Lin, Shin-Cheh Chen, Shu-Hang Ng
OBJECTIVE: To retrospectively analyze the quantitative measurement and kinetic enhancement among pathologically proven benign and malignant lesions using contrast-enhanced spectral mammography (CESM). METHODS: We investigated the differences in enhancement between 44 benign and 108 malignant breast lesions in CESM, quantifying the extent of enhancements and the relative enhancements between early (between 2-3 min after contrast medium injection) and late (3-6 min) phases...
February 27, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29399622/visual-adaptation-and-the-amplitude-spectra-of-radiological-images
#5
Elysse Kompaniez-Dunigan, Craig K Abbey, John M Boone, Michael A Webster
We examined how visual sensitivity and perception are affected by adaptation to the characteristic amplitude spectra of X-ray mammography images. Because of the transmissive nature of X-ray photons, these images have relatively more low-frequency variability than natural images, a difference that is captured by a steeper slope of the amplitude spectrum (~ - 1.5) compared to the ~ 1/f (slope of - 1) spectra common to natural scenes. Radiologists inspecting these images are therefore exposed to a different balance of spectral components, and we measured how this exposure might alter spatial vision...
2018: Cognitive Research: Principles and Implications
https://www.readbyqxmd.com/read/29374745/intensity-and-pattern-of-enhancement-on-cesm-prognostic-significance-and-its-relation-to-expression-of-podoplanin-in-tumor-stroma-a-preliminary-report
#6
Elzbieta Luczynska, Joanna Niemiec, Sylwia Heinze, Agnieszka Adamczyk, Aleksandra Ambicka, Paulina Marcyniuk, Wojciech Rudnicki, Jerzy W Mitus, Sonia Dyczek, Janusz Rys, Beata Sas-Korczynska
BACKGROUND/AIM: It is possible that the degree of enhancement on contrast-enhanced spectral mammography (CESM), a new diagnostic method, might provide prognostic information for breast cancer patients. Therefore, in a group of 82 breast cancer patients, we analyzed the prognostic significance of degree and pattern of enhancement on CESM as well as its relation to: (a) breast cancer immunophenotype (based on ER/PR/HER2 status) (b) podoplanin expression in cancer stroma (lymphatic vessel density plus podoplanin-positivity of cancer-associated fibroblasts), and (c) other histological parameters...
February 2018: Anticancer Research
https://www.readbyqxmd.com/read/29317041/contrast-enhanced-spectral-mammography-a-review
#7
Bhavika K Patel, M B I Lobbes, John Lewin
Contrast-enhanced spectral mammography (CESM) provides low-energy 2D mammographic images comparable to standard digital mammography and a post-contrast recombined image to assess tumor neovascularity similar to magnetic resonance imaging (MRI). The utilization of CESM in the United States is currently low but could increase rapidly given many potential indications for clinical use. This article discusses historical background and literature review of indications and diagnostic accuracy of CESM to date. CESM is a growing technique for breast cancer detection and diagnosis that has levels of sensitivity and specificity on par with contrast-enhanced breast MRI...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29279165/computer-aided-diagnosis-of-contrast-enhanced-spectral-mammography-a-feasibility-study
#8
Bhavika K Patel, Sara Ranjbar, Teresa Wu, Barbara A Pockaj, Jing Li, Nan Zhang, Mark Lobbes, Bin Zhang, J Ross Mitchell
OBJECTIVE: To evaluate whether the use of a computer-aided diagnosis-contrast-enhanced spectral mammography (CAD-CESM) tool can further increase the diagnostic performance of CESM compared with that of experienced radiologists. MATERIALS AND METHODS: This IRB-approved retrospective study analyzed 50 lesions described on CESM from August 2014 to December 2015. Histopathologic analyses, used as the criterion standard, revealed 24 benign and 26 malignant lesions. An expert breast radiologist manually outlined lesion boundaries on the different views...
January 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29221721/factors-affecting-the-precision-of-lesion-sizing-with-contrast-enhanced-spectral-mammography
#9
M Del Mar Travieso-Aja, P Naranjo-Santana, C Fernández-Ruiz, W Severino-Rondón, D Maldonado-Saluzzi, M Rodríguez Rodríguez, V Vega-Benítez, O P Luzardo
AIM: To evaluate the precision of the pre-surgical measurement of the size of breast cancer by contrast-enhanced spectral mammography (CESM). MATERIAL AND METHODS: This was a retrospective study of 204 breast cancers. Variables related to tumour biology and anthropometric variables were recorded and considered when evaluating the efficacy of CESM in predicting tumour size. Microscopic measurement of the largest diameter of the tumour at pathology was chosen as the reference standard...
March 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29159881/characterization-of-photon-counting-multislit-breast-tomosynthesis
#10
Karl Berggren, Björn Cederström, Mats Lundqvist, Erik Fredenberg
PURPOSE: It has been shown that breast tomosynthesis may improve sensitivity and specificity compared to two-dimensional mammography, resulting in increased detection-rate of cancers or lowered call-back rates. The purpose of this study is to characterize a spectral photon-counting multislit breast tomosynthesis system that is able to do single-scan spectral imaging with multiple collimated x-ray beams. The system differs in many aspects compared to conventional tomosynthesis using energy-integrating flat-panel detectors...
February 2018: Medical Physics
https://www.readbyqxmd.com/read/29097928/assessing-the-risk-of-contrast-induced-nephropathy-using-a-finger-stick-analysis-in-recalls-from-breast-screening-the-cinfibs-explorative-study
#11
I P L Houben, C J L Y van Berlo, O Bekers, E C Nijssen, M B I Lobbes, J E Wildberger
Purpose: To evaluate whether a handheld point-of-care (POC) device is able to predict and discriminate patients at potential risk of contrast-induced nephropathy (CIN) prior to iodine-based contrast media delivery. Methods and Materials: Between December 2014 and June 2016, women undergoing contrast-enhanced spectral mammography (CESM) with an iodine-based contrast agent were asked to have their risk of CIN assessed by a dedicated POC device (StatSensor CREAT) and a risk factor questionnaire based on national guidelines...
2017: Contrast Media & Molecular Imaging
https://www.readbyqxmd.com/read/29058963/contrast-enhanced-spectral-mammography-in-patients-with-mri-contraindications
#12
Vivien Richter, Valerie Hatterman, Heike Preibsch, Sonja D Bahrs, Markus Hahn, Konstantin Nikolaou, Benjamin Wiesinger
Background Contrast-enhanced spectral mammography (CESM) is a novel breast imaging technique providing comparable diagnostic accuracy to breast magnetic resonance imaging (MRI). Purpose To show that CESM in patients with MRI contraindications is feasible, accurate, and useful as a problem-solving tool, and to highlight its limitations. Material and Methods A total of 118 patients with MRI contraindications were examined by CESM. Histology was obtained in 94 lesions and used as gold standard for diagnostic accuracy calculations...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28941757/contrast-enhanced-spectral-mammography-as-work-up-tool-in-patients-recalled-from-breast-cancer-screening-has-low-risks-and-might-hold-clinical-benefits
#13
I P L Houben, P Van de Voorde, C R L P N Jeukens, J E Wildberger, L F Kooreman, M L Smidt, M B I Lobbes
OBJECTIVE: Contrast-enhanced spectral mammography (CESM) is a reliable problem solving tool in the work-up of women recalled from breast cancer screening. We evaluated additional findings caused by CESM alone and outweighed them against the disadvantages of this technique. METHODS: From December 2012 to December 2015, all women recalled from screening who underwent CESM were considered for this study. Radiation exposure and number of adverse contrast reactions were analysed...
September 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28899968/multispectral-optoacoustic-tomography-msot-of-human-breast-cancer
#14
Gael Diot, Stephan Metz, Aurelia Noske, Evangelos Liapis, Barbara Schroeder, Saak V Ovsepian, Reinhard Meier, Ernst Rummeny, Vasilis Ntziachristos
Purpose: In a pilot study, we introduce fast handheld multispectral optoacoustic tomography (MSOT) of the breast at 28 wavelengths, aiming to identify high-resolution optoacoustic (photoacoustic) patterns of breast cancer and noncancerous breast tissue.Experimental Design: We imaged 10 female patients ages 48-81 years with malignant nonspecific breast cancer or invasive lobular carcinoma. Three healthy volunteers ages 31-36 years were also imaged. Fast-MSOT was based on unique single-frame-per-pulse (SFPP) image acquisition employed to improve the accuracy of spectral differentiation over using a small number of wavelengths...
September 12, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28894329/accuracy-of-contrast-enhanced-spectral-mammography-for-estimating-residual-tumor-size-after-neoadjuvant-chemotherapy-in-patients-with-breast-cancer-a-feasibility-study
#15
Filipe Ramos Barra, Fernanda Freire de Souza, Rosimara Eva Ferreira Almeida Camelo, Andrea Campos de Oliveira Ribeiro, Luciano Farage
OBJECTIVE: To assess the feasibility of contrast-enhanced spectral mammography (CESM) of the breast for assessing the size of residual tumors after neoadjuvant chemotherapy (NAC). MATERIALS AND METHODS: In breast cancer patients who underwent NAC between 2011 and 2013, we evaluated residual tumor measurements obtained with CESM and full-field digital mammography (FFDM). We determined the concordance between the methods, as well as their level of agreement with the pathology...
July 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28893303/contrast-enhanced-spectral-mammography-in-neoadjuvant-chemotherapy-monitoring-a-comparison-with-breast-magnetic-resonance-imaging
#16
Valentina Iotti, Sara Ravaioli, Rita Vacondio, Chiara Coriani, Sabrina Caffarri, Roberto Sghedoni, Andrea Nitrosi, Moira Ragazzi, Elisa Gasparini, Cristina Masini, Giancarlo Bisagni, Giuseppe Falco, Guglielmo Ferrari, Luca Braglia, Alberto Del Prato, Ivana Malavolti, Vladimiro Ginocchi, Pierpaolo Pattacini
BACKGROUND: Neoadjuvant-chemotherapy (NAC) is considered the standard treatment for locally advanced breast carcinomas. Accurate assessment of disease response is fundamental to increase the chances of successful breast-conserving surgery and to avoid local recurrence. The purpose of this study was to compare contrast-enhanced spectral mammography (CESM) and contrast-enhanced-MRI (MRI) in the evaluation of tumor response to NAC. METHODS: This prospective study was approved by the institutional review board and written informed consent was obtained...
September 11, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28870431/could-parenchymal-enhancement-on-contrast-enhanced-spectral-mammography-cesm-represent-a-new-breast-cancer-risk-factor-correlation-with-known-radiology-risk-factors
#17
S L Savaridas, D B Taylor, D Gunawardana, M Phillips
AIM: To compare background parenchymal enhancement (BPE) on contrast-enhanced (CE) spectral mammography (CESM) with CE magnetic resonance imaging (MRI), and evaluate how these relate to hormonal status, mammographic breast density (MBD) and MRI fibroglandular tissue volume (FGTV). METHODS AND MATERIALS: Between June 2012 to October 2015, participants in a cancer staging study underwent full-field digital mammography (FFDM), CEMRI, and CESM. Two readers independently rated FGTV, MBD, and BPE using the Breast Imaging-Reporting and Data System (BI-RADS) criteria...
December 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28783629/low-dose-contrast-enhanced-breast-ct-using-spectral-shaping-filters-an-experimental-study
#18
Andrey Makeev, Stephen J Glick
Iodinated contrast-enhanced X-ray imaging of the breast has been studied with various modalities, including full-field digital mammography (FFDM), digital breast tomosynthesis (DBT), and dedicated breast CT. Contrast imaging with breast CT has a number of advantages over FFDM and DBT, including the lack of breast compression, and generation of fully isotropic 3-D reconstructions. Nonetheless, for breast CT to be considered as a viable tool for routine clinical use, it would be desirable to reduce radiation dose...
December 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28750354/assessing-tumor-extent-on-contrast-enhanced-spectral-mammography-versus-full-field-digital-mammography-and-ultrasound
#19
Bhavika K Patel, Sandra Alheli Garza, Sarah Eversman, Yania Lopez-Alvarez, Heidi Kosiorek, Barbara A Pockaj
OBJECTIVES: To compare breast cancer size measurements on full-field digital mammography (FFDM), contrast-enhanced spectral mammography (CEDM), and ultrasound (US), with histologic tumor size used as the reference standard. Material and methods The HIPAA complaint, IRB approved study comprised 88 women with newly diagnosed breast cancer who underwent FFDM and CEDM;74 also had US. Breast density, histologic subtype, and maximum tumor measurements were recorded. RESULTS: Pearson correlation coefficients for FFDM, US, and CEDM vs histopathology were 0...
November 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28723585/clinical-utility-of-contrast-enhanced-spectral-mammography-as-an-adjunct-for-tomosynthesis-detected-architectural-distortion
#20
Bhavika K Patel, Michelle E Naylor, Heidi E Kosiorek, Yania M Lopez-Alvarez, Adrian M Miller, Victor J Pizzitola, Barbara A Pockaj
OBJECTIVE: Supplement tomosynthesis-detected architectural distortions (AD) with CESM to better characterize malignant vs benign lesions. METHODS: Retrospective review CESM prior to biopsied AD. Pathology: benign, radial scar, or malignant. RESULTS: 49 lesions (45 patients). 29 invasive cancers, 1 DCIS (range, 0.4-4.7cm); 9 radial scars; 10 benign. 37 (75.5%) ADs had associated enhancement. PPV 78.4% (29/37), sensitivity 96.7% (29/30); specificity, 57...
November 2017: Clinical Imaging
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