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https://www.readbyqxmd.com/read/27900294/efficacy-of-autologous-leukocyte-reduced-platelet-rich-plasma-therapy-for-patellar-tendinopathy-in-a-rat-treadmill-model
#1
Mamoru Yoshida, Hiroki Funasaki, Keishi Marumo
BACKGROUND: An autologous platelet-rich plasma (PRP) therapy has currently been applied for the tendinopathy; however, its efficacy and an optimal platelets concentration in PRP were uncertain. We analyzed them in an animal model prepared using a repetitive running exercise. METHODS: We made the tendinopathy rat model of patellar tendon using a rodent treadmill machine. Rats with tendinopathy were injected with leukocyte-reduced PRP at the platelets concentration of 1...
April 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27857633/clinical-effectiveness-of-dry-needling-immediately-after-application-on-myofascial-trigger-point-in-upper-trapezius-muscle
#2
Maryam Ziaeifar, Amir Massoud Arab, Mohammad Reza Nourbakhsh
OBJECTIVE: The purpose of this study was to investigate the effect of dry needling (DN) on pain intensity and pressure pain threshold (PPT) compared with ischemic compression (IC) immediately and 48 hours after each treatment session in individuals with myofascial trigger points in the upper trapezius muscle. METHODS: Thirty-one patients with myofascial trigger points in the upper trapezius muscle participated in this study. Patients were randomly assigned to a standard (N = 17) or experimental group (N = 14)...
December 2016: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/27834590/clinical-effects-of-dry-needling-among-asymptomatic-individuals-with-hamstring-tightness-a-randomized-controlled-trial
#3
Kathleen Geist, Claire Bradley, Alan Hofman, Rob Koester, Fenella Roche, Annalise Shields, Elizabeth Frierson, Ainsley Rossi, Marie Johanson
STUDY DESIGN: Randomized controlled trial. OBJECTIVES: The aim of this study was to determine the effects of dry needling on hamstring extensibility and functional performance tests among asymptomatic individuals with hamstring muscle tightness. BACKGROUND: Dry needling has been shown to increase range of motion in the upper quarter and may have similar effects in the lower quarter. METHODS: Twenty-seven subjects with hamstring extensibility deficits were randomly assigned to side of treatment (dominant or non-dominant) and group (blunt needling or dry needling)...
November 11, 2016: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/27819524/presentation-matters-buffers-packaging-and-delivery-devices-for-new-oral-enteric-vaccines-for-infants
#4
Manjari Lal, Courtney Jarrahian
Oral administration of vaccines is simpler and more acceptable than injection via needle and syringe, particularly for infants (Figure 1.) This route is promising for new vaccines in development against enterotoxigenic Escherichia coli (ETEC) and Shigella that cause childhood diarrhea with devastating consequences in low-resource countries. However, vaccine antigens and adjuvants given orally need buffering against the degradative effects of low stomach pH, and the type and volume of antacid buffer require special attention for infants...
November 7, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27814870/a-critical-overview-of-the-current-myofascial-pain-literature-september-2016
#5
Jan Dommerholt, Michelle Finnegan, Todd Hooks, Rob Grieve
This edition of the overview of the current myofascial pain literature includes 24 studies, case reports and systematic and narrative reviews. Surprisingly, five of the 24 papers were difficult to read and interpret mostly because of a poor mastery of the English language. It is somewhat surprising that journal editors and reviewers would accept papers that are needlessly difficult to read and not direct the authors to language services or others who could improve the quality of the writings. Of course, it is exciting that researchers and clinicians from all over the world continue to focus on myofascial pain and attempt to shed new light on the complexity of the problem to improve the clinical decision-making process and eventually clinical approaches and outcomes...
October 2016: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/27757293/pertinent-dry-needling-considerations-for-minimizing-adverse-effects-part-two
#6
John S Halle, Rob J Halle
BACKGROUND: Dry needling (DN) is an evidence based treatment technique that is accepted and used by physical therapists in the United States. This clinical commentary is the second in a two-part series outlining some of the pertinent anatomy and other issues that are needed for optimal utilization of this treatment modality. Part one was an overview of the thorax with a summary of reported adverse effects (AEs) and the underlying anatomy that could be used to minimize patient risk. As is the case with any intervention, the technique of dry needling has some inherent patient risk...
October 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27757280/the-effectiveness-of-dry-needling-and-stretching-vs-stretching-alone-on-hamstring-flexibility-in-patients-with-knee-pain-a-randomized-controlled-trial
#7
John S Mason, Michael Crowell, Jeffery Dolbeer, Jamie Morris, Aspen Terry, Shane Koppenhaver, Donald Lee Goss
BACKGROUND: Recently, dry needling has emerged as a popular treatment for muscular pain and impairments. While there are numerous studies detailing the benefits of dry needling for pain, few studies exist examining the effects on soft tissue mobility. PURPOSE: The purpose of this study was to determine if the addition of hamstring dry needling to a standard stretching program results in greater improvements in hamstring flexibility compared to sham dry needling and stretching in subjects with atraumatic knee pain...
October 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27755912/genomic-adequacy-from-solid-tumor-core-needle-biopsies-of-ex-vivo-tissue-and-in-vivo-lung-masses-prospective-study
#8
Neema Jamshidi, Danshan Huang, Fereidoun G Abtin, Christopher T Loh, Stephen T Kee, Robert D Suh, Shota Yamamoto, Kingshuk Das, Sarah Dry, Scott Binder, Dieter R Enzmann, Michael D Kuo
Purpose To identify the variables and factors that affect the quantity and quality of nucleic acid yields from imaging-guided core needle biopsy. Materials and Methods This study was approved by the institutional review board and compliant with HIPAA. The authors prospectively obtained 232 biopsy specimens from 74 patients (177 ex vivo biopsy samples from surgically resected masses were obtained from 49 patients and 55 in vivo lung biopsy samples from computed tomographic [CT]-guided lung biopsies were obtained from 25 patients) and quantitatively measured DNA and RNA yields with respect to needle gauge, number of needle passes, and percentage of the needle core...
October 18, 2016: Radiology
https://www.readbyqxmd.com/read/27747222/sacro-iliac-joint-sensory-block-and-radiofrequency-ablation-assessment-of-bony-landmarks-relevant-for-image-guided-procedures
#9
Trevor J G Robinson, Shannon L Roberts, Robert S Burnham, Eldon Loh, Anne M Agur
Image-guided sensory block and radiofrequency ablation of the nerves innervating the sacro-iliac joint require readily identifiable bony landmarks for accurate needle/electrode placement. Understanding the relative locations of the transverse sacral tubercles along the lateral sacral crest is important for ultrasound guidance, as they demarcate the position of the posterior sacral network (S1-S3 ± L5/S4) innervating the posterior sacro-iliac joint. No studies were found that investigated the spatial relationships of these bony landmarks...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27720812/exercises-and-dry-needling-for-subacromial-pain-syndrome-a-randomized-parallel-group-trial
#10
José L Arias-Buría, César Fernández-de-Las-Peñas, María Palacios-Ceña, Shane L Koppenhaver, Jaime Salom-Moreno
: This randomized clinical trial investigated the effectiveness of exercise vs. exercise plus trigger point dry needling (TrP-DN) in subacromial pain syndrome. A randomized parallel-group trial, with 1-year follow-up was conducted. Fifty subjects with subacromial pain syndrome were randomly allocated to receive exercise alone or exercise +TrP-DN. Participants in both groups were asked to perform an exercise program of the rotator cuff muscles twice daily for 5 weeks. Further, patients allocated to the exercise +TrP-DN group also received dry needling to active TrPs in the muscles reproducing shoulder symptoms during the 2(nd) and 4(th) sessions...
October 5, 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27720020/exome-and-genome-sequencing-for-inborn-errors-of-immunity
#11
REVIEW
Isabelle Meyts, Barbara Bosch, Alexandre Bolze, Bertrand Boisson, Yuval Itan, Aziz Belkadi, Vincent Pedergnana, Leen Moens, Capucine Picard, Aurélie Cobat, Xavier Bossuyt, Laurent Abel, Jean-Laurent Casanova
The advent of next-generation sequencing (NGS) in 2010 has transformed medicine, particularly the growing field of inborn errors of immunity. NGS has facilitated the discovery of novel disease-causing genes and the genetic diagnosis of patients with monogenic inborn errors of immunity. Whole-exome sequencing (WES) is presently the most cost-effective approach for research and diagnostics, although whole-genome sequencing offers several advantages. The scientific or diagnostic challenge consists in selecting 1 or 2 candidate variants among thousands of NGS calls...
October 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27717676/an-enhanced-approach-for-the-use-of-satellite-derived-leaf-area-index-values-in-dry-deposition-modeling-in-the-athabasca-oil-sands-region
#12
Mervyn Davies, Sunny Cho, David Spink, Ron Pauls, Michael Desilets, Yan Shen, Kanwardeep Bajwa, Reid Person
In the Athabasca oil sands region (AOSR) of Northern Alberta, the dry deposition of sulphur and nitrogen compounds represents a major fraction of total (wet plus dry) deposition due to oil sands emissions. The leaf area index (LAI) is a critical parameter that affects the dry deposition of these gaseous and particulate compounds to the surrounding boreal forest canopy. For this study, LAI values based on Moderate Resolution Imaging Spectroradiometer satellite imagery were obtained and compared to ground-based measurements, and two limitations with the satellite data were identified...
October 4, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/27711262/toward-self-powered-wearable-adhesive-skin-patch-with-bendable-microneedle-array-for-transdermal-drug-delivery
#13
Hao Wang, Giorgia Pastorin, Chengkuo Lee
A wearable adhesive skin patch for transdermal drug delivery is developed with bendable microneedles, dry adhesive and triboelectric energy harvester (TEH). The bendable microneedle array can overcome the needle breakage issue. The dry adhesive can realize a conformal attachment. The TEH can generate power when attached on flat skin or joint to power active components to be integrated in the future.
September 2016: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://www.readbyqxmd.com/read/27697769/effects-of-myofascial-trigger-point-dry-needling-in-patients-with-sleep-bruxism-and-temporomandibular-disorders-a-prospective-case-series
#14
Paloma María Blasco-Bonora, Aitor Martín-Pintado-Zugasti
OBJECTIVES: To investigate the effects of deep dry needling (DN) of myofascial trigger points (MTrPs) of the masseter and temporalis on pain, pressure pain threshold (PPT), pain-free maximal jaw opening and temporomandibular disorder (TMD)-related disability in patients with sleep bruxism (SB) and myofascial TMD. METHODS: Seventeen subjects (11 women, 6 men) aged 39±13 years (range 23-66) diagnosed with SB and myofascial TMD were invited to participate in this prospective case series study...
October 3, 2016: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/27697768/therapeutic-effects-of-dry-needling-in-patients-with-upper-trapezius-myofascial-trigger-points
#15
Maryam Abbaszadeh-Amirdehi, Noureddin Nakhostin Ansari, Soofia Naghdi, Gholamreza Olyaei, Mohammad Reza Nourbakhsh
BACKGROUND: Active myofascial trigger points (MTrPs) are major pain generators in myofascial pain syndrome. Dry needling (DN) is an effective method for the treatment of MTrPs. OBJECTIVE: To assess the immediate neurophysiological and clinical effects of DN in patients with upper trapezius MTrPs. METHODS: This was a prospective, clinical trial study of 20 patients with upper trapezius MTrPs and 20 healthy volunteers (matched for height, weight, body mass index and age), all of whom received one session of DN...
October 3, 2016: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/27690230/turnover-of-137-cs-in-soil-tree-system-an-experience-of-measuring-the-isotope-flows-in-a-siberian-conifer-forest
#16
Vladimir L Gavrikov, Ruslan A Sharafutdinov, Aleksandr R Mitev
Little attention has been paid to the uptake of (137)Cs in natural forests under low levels of the isotope fallout when no immediate ecological danger presents. Here we present the extended assessments of the soil-to-plant and canopy-to-litter flows of (137)Cs recently evaluated in a native Siberian forested area. The area undergoes a typical after-fire long term succession, with light-conifer upper story being followed by undergrowth of Siberian fir and other dark-conifer species. The one-year-old needles of Siberian fir were found to accumulate the largest concentration of the isotope, 4...
December 2016: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/27685009/effect-of-dry-needling-on-thigh-muscle-strength-and-hip-flexion-in-elite-soccer-players
#17
Christian Haser, Thomas Stöggl, Monika Kriner, Jörg Mikoleit, Bernd Wolfahrt, Johannes Scherr, Martin Halle, Florian Pfab
PURPOSE: Increase in muscle force, endurance and flexibility is desired in elite athletes in order to improve performance and avoid injuries but often hindered by occurence of myofascial trigger points. Dry needling (DN) has been shown effective in eliminating myofascial trigger points. METHODS: This randomized controlled study in 30 elite youth soccer players of a professional soccer Bundesliga Club investigated the effects of four weekly sessions of DN plus water-pressure-massage on thigh muscle force and range-of-motion of hip flexion...
September 28, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27683642/dry-needling-in-patients-with-chronic-heel-pain-due-to-plantar-fasciitis-a-single-blinded-randomized-clinical-trial
#18
Bina Eftekharsadat, Arash Babaei-Ghazani, Vahideh Zeinolabedinzadeh
BACKGROUND: This study examined the effects of dry needling on chronic heel pain due to plantar fasciitis. METHODS: During this single-blinded clinical trial, 20 eligible patients were randomized into two groups: A case group treated with dry needling and a control group. Patients' plantar pain severity, (using modified visual analog scale [VAS] scoring system), range of motion of ankle joint in dorsiflexion [ROMDF] and plantar extension[ROMPE] and foot function index (using standard questionnaires of SEM5 and MDC7) were assessed at baseline, four weeks after intervention and four weeks after withdrawing treatment...
2016: Medical Journal of the Islamic Republic of Iran
https://www.readbyqxmd.com/read/27679516/the-delivery-of-high-dose-dry-powder-antibiotics-by-a-low-cost-generic-inhaler
#19
Thaigarajan Parumasivam, Sharon S Y Leung, Patricia Tang, Citterio Mauro, Warwick Britton, Hak-Kim Chan
The routine of loading multiple capsules for delivery of high-dose antibiotics is time consuming, which may reduce patient adherence to inhaled treatment. To overcome this limitation, an investigation was carried out using four modified versions of the Aerolizer® that accommodate a size 0 capsule for delivery of high payload formulations. In some prototypes, four piercing pins of 0.6 mm each were replaced with a single centrally located 1.2-mm pin and one-third reduced air inlet of the original design. The performance of these inhalers was evaluated using spray-dried antibiotic powders with distinct morphologies: spherical particles with a highly corrugated surface (colistin and tobramycin) and needle-like particles (rifapentine)...
September 27, 2016: AAPS Journal
https://www.readbyqxmd.com/read/27673531/-no-touch-technique-for-lip-enhancement
#20
Christopher C Surek, Eva Guisantes, Kenna Schnarr, Glenn Jelks, Javier Beut
BACKGROUND: The purpose of this study was to examine the anatomical principles of lip structure as they relate to individualized lip enhancement procedures and to describe a technique that does not violate lip mucosa during injection. METHODS: A retrospective analysis of patients undergoing lip enhancement procedures between 2001 and 2014 was performed. Preprocedural and postprocedural photographs were analyzed for lip subunit changes. A stepwise treatment algorithm targeting specific anatomical subunits of lip is described...
October 2016: Plastic and Reconstructive Surgery
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