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Contrast enhanced digital mammography

Eva M Fallenberg, Florian F Schmitzberger, Heba Amer, Barbara Ingold-Heppner, Corinne Balleyguier, Felix Diekmann, Florian Engelken, Ritse M Mann, Diane M Renz, Ulrich Bick, Bernd Hamm, Clarisse Dromain
OBJECTIVES: To compare the diagnostic performance of contrast-enhanced spectral mammography (CESM) to digital mammography (MG) and magnetic resonance imaging (MRI) in a prospective two-centre, multi-reader study. METHODS: One hundred seventy-eight women (mean age 53 years) with invasive breast cancer and/or DCIS were included after ethics board approval. MG, CESM and CESM + MG were evaluated by three blinded radiologists based on amended ACR BI-RADS criteria...
November 28, 2016: European Radiology
Francesco Sardanelli, Eva M Fallenberg, Paola Clauser, Rubina M Trimboli, Julia Camps-Herrero, Thomas H Helbich, Gabor Forrai
: This article summarises the information to be offered to women about mammography. After a delineation of the aim of early diagnosis of breast cancer, the difference between screening mammography and diagnostic mammography is explained. The need to bring images and reports from the previous mammogram (and from other recent breast imaging examinations) is highlighted. Mammography technique and procedure are described with particular attention to discomfort and pain experienced by a small number of women who undergo the test...
November 16, 2016: Insights Into Imaging
Maria Del Mar Travieso Aja, Purificacion Munoz, Mario Rodriguez Rodriguez, Victor Vega Benitez, Octavio P Luzardo
Up to 19% of breast malignancies may be missed by conventional imaging techniques, especially when they are concurrent or co-located with other benign lesions. However, more sensitive techniques, such as magnetic resonance imaging (MRI), are often too expensive for routine use in developing countries. Contrast-enhanced, dual-energy digital mammography (CESM) is a recently introduced imaging modality whose performance has been reported to be similar to that of MRI. Being much cheaper, CESM may constitute a good alternative for improving diagnostic sensitivity in these countries...
July 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
Chandni Bhimani, Danielle Matta, Robyn G Roth, Lydia Liao, Elizabeth Tinney, Kristin Brill, Pauline Germaine
RATIONALE AND OBJECTIVES: Contrast-enhanced spectral mammography (CESM) combines the benefits of full field digital mammography with the concept of tumor angiogenesis. Technique and practical applications of CESM are discussed. MATERIALS AND METHODS: An overview of the technique is followed by a demonstration of practical applications of CESM in our practice. RESULTS: We have successfully implemented CESM into our practice as a screening, diagnostic, staging, and treatment response tool...
October 20, 2016: Academic Radiology
Chandni Bhimani, Luna Li, Lydia Liao, Robyn G Roth, Elizabeth Tinney, Pauline Germaine
RATIONALE AND OBJECTIVES: Contrast-enhanced spectral mammography (CESM) uses full field digital mammography with the added benefit of intravenous contrast administration to significantly reduce false-positive and false-negative results and improve specificity while maintaining high sensitivity. For CESM to fulfill its purpose, one should be aware of possible artifacts and other factors which may interfere with image quality, and attention should be taken to minimize these factors. MATERIALS AND METHODS: This pictorial demonstration will depict types of artifacts detected and other factors that interfere with image acquisition in our practice since CESM implementation...
October 17, 2016: Academic Radiology
Tiffany C Lewis, Victor J Pizzitola, Marina E Giurescu, William G Eversman, Roxanne Lorans, Kristin A Robinson, Bhavika K Patel
Contrast-enhanced digital mammography (CEDM) is the only imaging modality that provides both (a) a high-resolution, low-energy image comparable to that of digital mammography and (b) a contrast-enhanced image similar to that of magnetic resonance imaging. We report the initial 208 CEDM examinations performed for various clinical indications and provide illustrative case examples. Given its success in recent studies and our experience of CEDM primarily as a diagnostic adjunct, CEDM can potentially improve breast cancer detection by combining the low-cost conclusions of screening mammography with the high sensitivity of magnetic resonance imaging...
October 2, 2016: Breast Journal
Mariam Ali-Mucheru, Barbara Pockaj, Bhavika Patel, Victor Pizzitola, Nabil Wasif, Chee-Chee Stucky, Richard Gray
BACKGROUND: Contrast-enhanced digital mammography (CEDM) is a new breast imaging technique. The role of CEDM in the surgical management of breast cancer has not yet been characterized. METHODS: A retrospective review of prospective breast surgery and breast imaging databases for patients who underwent CEDM and had breast cancer surgery. RESULTS: A total of 351 patients had CEDM; 128 had malignant lesions, and 101 of these underwent surgery with 105 malignancies identified...
September 15, 2016: Annals of Surgical Oncology
M Funke
Advances in imaging of the female breast have substantially influenced the diagnosis and probably also the therapy and prognosis of breast cancer in the past few years. This article gives an overview of the most important imaging modalities in the diagnosis of breast cancer. Digital mammography is considered to be the gold standard for the early detection of breast cancer. Digital breast tomosynthesis can increase the diagnostic accuracy of mammography and is used for the assessment of equivocal or suspicious mammography findings...
October 2016: Der Radiologe
Alexandra Tsigginou, Christina Gkali, Athanasios Chalazonitis, Eleni Feida, Dimitrios Efthymios Vlachos, Flora Zagouri, Ioannis Rellias, Constantine Dimitrakakis
OBJECTIVE: Despite advancements in technology, mammography remains the golden standard in breast cancer diagnosis and in mortality reduction. Overtime, digital mammography combined with other imaging modalities supported a trend to more accurately presume pathological diagnosis. Dual-energy Contrast Enhanced Spectral Mammography (CESM) represents a relatively new diagnostic tool adjunct to mammography. The aim of this study is to strengthen the BIRADS classification score in order to improve early breast cancer diagnosis...
July 25, 2016: British Journal of Radiology
Giovanna Mariscotti, Paolo Belli, Daniela Bernardi, Beniamino Brancato, Massimo Calabrese, Luca A Carbonaro, Beatrice Cavallo-Marincola, Francesca Caumo, Paola Clauser, Laura Martinchich, Stefania Montemezzi, Pietro Panizza, Federica Pediconi, Alberto Tagliafico, Rubina M Trimboli, Chiara Zuiani, Francesco Sardanelli
Women who underwent chest radiation therapy (CRT) during pediatric/young-adult age (typically, lymphoma survivors) have an increased breast cancer risk, in particular for high doses. The cumulative incidence from 40 to 45 years of age is 13-20 %, similar to that of BRCA mutation carriers for whom contrast-enhanced magnetic resonance imaging (MRI) is recommended. However, in women who underwent CRT, MRI sensitivity is lower (63-80 %) and that of mammography higher (67-70 %) than those observed in women with hereditary predisposition, due to a higher incidence of ductal carcinoma in situ with microcalcifications and low neoangiogenesis...
July 12, 2016: La Radiologia Medica
María-Ester Brandan, Juan P Cruz-Bastida, Iván M Rosado-Méndez, Yolanda Villaseñor-Navarro, Héctor Pérez-Ponce, Héctor A Galván, Flavio E Trujillo-Zamudio, Patricia Sánchez-Suárez, Luis Benítez-Bribiesca
OBJECTIVE: To correlate image parameters in contrast-enhanced digital mammography (CEDM) with blood and lymphatic microvessel density (MVD). METHODS: 18 Breast Imaging-Reporting and Data System (BI-RADS)-4 to BI-RADS-5 patients were subjected to CEDM. Craniocaudal views were acquired, two views (low and high energy) before iodine contrast medium (CM) injection and four views (high energy) 1-5 min afterwards. Processing included registration and two subtraction modalities, traditional single-energy temporal (high-energy) and "dual-energy temporal with a matrix", proposed to improve lesion conspicuity...
September 2016: British Journal of Radiology
Adriano Contillo, Giovanni Di Domenico, Paolo Cardarelli, Mauro Gambaccini, Angelo Taibi
PURPOSE: Dual-energy image subtraction represents a useful tool to improve the detectability of small lesions, especially in dense breasts. A feature it shares with all x-ray imaging techniques is the appearance of fluctuations in the texture of the background, which can obscure the visibility of interesting details. The aim of the work is to investigate the main noise sources, in order to create a better performing subtraction mechanism. In particular, the structural noise cancellation was achieved by means of a suitable extension of the dual-energy algorithm...
June 2016: Medical Physics
Jeffrey S Nelson, Jered R Wells, Jay A Baker, Ehsan Samei
PURPOSE: The FDA approved the use of digital breast tomosynthesis (DBT) in 2011 as an adjunct to 2D full field digital mammography (FFDM) with the constraint that all DBT acquisitions must be paired with a 2D image to assure adequate interpretative information is provided. Recently manufacturers have developed methods to provide a synthesized 2D image generated from the DBT data with the hope of sparing patients the radiation exposure from the FFDM acquisition. While this much needed alternative effectively reduces the total radiation burden, differences in image quality must also be considered...
May 2016: Medical Physics
Bassam H Rimawi, Victoria Green, Michael Lindsay
The purpose of this article is to review the fetal and long-term implications of diagnostic radiation exposure during pregnancy. Evidence-based recommendations for radiologic imaging modalities utilizing exposure of diagnostic radiation during pregnancy, including conventional screen-film mammography, digital mammography, tomosynthesis, and contrast-enhanced mammography are described.
June 2016: Clinical Obstetrics and Gynecology
Miki Mori, Sadako Akashi-Tanaka, Satoko Suzuki, Murasaki Ikeda Daniels, Chie Watanabe, Masanori Hirose, Seigo Nakamura
BACKGROUND: Contrast-enhanced spectral mammography to compare clinical efficacy of contrast-enhanced spectral mammography (CESM) and conventional digital mammography (MMG) with histopathology as gold standard in dense breasts. PATIENTS AND METHODS: A total of 143 breasts of 72 women who underwent CESM and MMG between 2011 and 2014 at Showa University Hospital were analyzed. RESULTS: 129 (90.2 %) of 143 breasts revealed dense breasts on MMG...
March 4, 2016: Breast Cancer: the Journal of the Japanese Breast Cancer Society
Lifang Si, Renyou Zhai, Xiaojuan Liu, Kaiyan Yang, Li Wang, Tao Jiang
PURPOSE: We aimed to evaluate the diagnostic accuracy of a combination of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and apparent diffusion coefficient (ADC) values in lesions that manifest with architectural distortion (AD) on mammography. METHODS: All full-field digital mammography (FFDM) images obtained between August 2010 and January 2013 were reviewed retrospectively, and 57 lesions showing AD were included in the study. Two independent radiologists reviewed all mammograms and MRI data and recorded lesion characteristics according to the BI-RADS lexicon...
March 2016: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
P S Vikhe, V R Thool
Detection of mass in mammogram for early diagnosis of breast cancer is a significant assignment in the reduction of the mortality rate. However, in some cases, screening of mass is difficult task for radiologist, due to variation in contrast, fuzzy edges and noisy mammograms. Masses and micro-calcifications are the distinctive signs for diagnosis of breast cancer. This paper presents, a method for mass enhancement using piecewise linear operator in combination with wavelet processing from mammographic images...
April 2016: Journal of Medical Systems
Ni He, Yao-Pan Wu, Yanan Kong, Ning Lv, Zhi-Mei Huang, Sheng Li, Yue Wang, Zhi-Jun Geng, Pei-Hong Wu, Wei-Dong Wei
PURPOSE: Breast cone-beam computed tomography (BCBCT) is a flat-panel detector (FPD)-based X-ray imaging system that provides high-quality images of the breast. The purpose of this study was to investigate the ability to detect breast abnormalities using non-contrast BCBCT and contrast-enhanced BCBCT (BCBCT and CE-BCBCT) compared to ultrasound (US) and digital mammography (MG). MATERIALS AND METHODS: A prospective study was performed from May 2012 to August 2014...
February 2016: European Journal of Radiology
W Peng, R V Mayorga, E M A Hussein
This paper presents an integrated system for the automatic analysis of mammograms to assist radiologists in confirming their diagnosis in mammography screening. The proposed automated confirmatory system (ACS) can process a digitalized mammogram online, and generates a high quality filtered segmentation of an image for biological interpretation and a texture-feature based diagnosis. We use a serial of image pre-processing and segmentation techniques, including 2D median filtering, seeded region growing (SRG) algorithm, image contrast enhancement, to remove noise, delete radiopaque artifacts and eliminate the projection of the pectoral muscle from a digitalized mammogram...
March 2016: Computer Methods and Programs in Biomedicine
Ana P Lourenco, Martha B Mainiero
Although some breast cancers present as palpable masses or with other clinical findings, many are detected at screening. Most screening is currently done with digital mammography, but high-risk patients or those with dense breast tissue may undergo additional screening examinations with magnetic resonance imaging or ultrasound. Additionally, digital breast tomosynthesis, contrast-enhanced mammography, and molecular breast imaging are newer technologies available at some sites. Optimal usage of breast imaging technologies remains controversial, both in screening and diagnostic settings following a new diagnosis of breast cancer...
January 2016: Seminars in Radiation Oncology
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