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Contrast enhanced digital mammography

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https://www.readbyqxmd.com/read/28987661/contamination-artifact-that-mimics-in-situ-carcinoma-on-contrast-enhanced-digital-mammography
#1
Jill Gluskin, Michael Click, Richard Fleischman, Clarisse Dromain, Elizabeth A Morris, Maxine S Jochelson
PURPOSE: Contrast-enhanced digital mammography (CEDM) is an advanced breast imaging technique using iodinated intravenous contrast to detect breast cancer. This article describes imaging features of a skin contamination artifact on CEDM that mimics in-situ carcinoma in a case series. MATERIALS AND METHODS: Five patients were identified whose CEDM images demonstrated apparent calcifications and non-mass enhancement suspicious for in-situ carcinoma, with no subsequent evidence of disease...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28894329/accuracy-of-contrast-enhanced-spectral-mammography-for-estimating-residual-tumor-size-after-neoadjuvant-chemotherapy-in-patients-with-breast-cancer-a-feasibility-study
#2
Filipe Ramos Barra, Fernanda Freire de Souza, Rosimara Eva Ferreira Almeida Camelo, Andrea Campos de Oliveira Ribeiro, Luciano Farage
OBJECTIVE: To assess the feasibility of contrast-enhanced spectral mammography (CESM) of the breast for assessing the size of residual tumors after neoadjuvant chemotherapy (NAC). MATERIALS AND METHODS: In breast cancer patients who underwent NAC between 2011 and 2013, we evaluated residual tumor measurements obtained with CESM and full-field digital mammography (FFDM). We determined the concordance between the methods, as well as their level of agreement with the pathology...
July 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28870431/could-parenchymal-enhancement-on-contrast-enhanced-spectral-mammography-cesm-represent-a-new-breast-cancer-risk-factor-correlation-with-known-radiology-risk-factors
#3
S L Savaridas, D B Taylor, D Gunawardana, M Phillips
AIM: To compare background parenchymal enhancement (BPE) on contrast-enhanced (CE) spectral mammography (CESM) with CE magnetic resonance imaging (MRI), and evaluate how these relate to hormonal status, mammographic breast density (MBD) and MRI fibroglandular tissue volume (FGTV). METHODS AND MATERIALS: Between June 2012 to October 2015, participants in a cancer staging study underwent full-field digital mammography (FFDM), CEMRI, and CESM. Two readers independently rated FGTV, MBD, and BPE using the Breast Imaging-Reporting and Data System (BI-RADS) criteria...
September 1, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28783629/low-dose-contrast-enhanced-breast-ct-using-spectral-shaping-filters-an-experimental-study
#4
Andrey Makeev, Stephen J Glick
Iodinated contrast-enhanced x-ray imaging of the breast has been studied with various modalities including, fullfield digital mammography (FFDM), digital breast tomosynthesis (DBT), and dedicated breast CT (BCT). Contrast imaging with breast CT has a number of advantages over FFDM and DBT including the lack of breast compression, and generation of fully isotropic, three-dimensional reconstructions. Nonetheless, for breast CT to be considered as a viable tool for routine clinical use, it would be desirable to reduce radiation dose...
August 2, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28780840/-diagnostic-value-of-quantitative-pharmacokinetic-parameters-and-relative-quantitative-pharmacokinetic-parameters-in-breast-lesions-with-dynamic-contrast-enhanced-mri
#5
T T Sun, W H Liu, Y Q Zhang, L H Li, R Wang, Y Y Ye
Objective: To explore the differential between the value of dynamic contrast-enhanced MRI quantitative pharmacokinetic parameters and relative pharmacokinetic quantitative parameters in breast lesions. Methods: Retrospective analysis of 255 patients(262 breast lesions) who was obtained by clinical palpation , ultrasound or full-field digital mammography , and then all lessions were pathologically confirmed in Zhongda Hospital, Southeast University from May 2012 to May 2016. A 3.0 T MRI scanner was used to obtain the quantitative MR pharmacokinetic parameters: volume transfer constant (K(trans)), exchange rate constant (k(ep))and extravascular extracellular volume fraction (V(e))...
August 1, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28750354/assessing-tumor-extent-on-contrast-enhanced-spectral-mammography-versus-full-field-digital-mammography-and-ultrasound
#6
Bhavika K Patel, Sandra Alheli Garza, Sarah Eversman, Yania Lopez-Alvarez, Heidi Kosiorek, Barbara A Pockaj
OBJECTIVES: To compare breast cancer size measurements on full-field digital mammography (FFDM), contrast-enhanced spectral mammography (CEDM), and ultrasound (US), with histologic tumor size used as the reference standard. Material and methods The HIPAA complaint, IRB approved study comprised 88 women with newly diagnosed breast cancer who underwent FFDM and CEDM;74 also had US. Breast density, histologic subtype, and maximum tumor measurements were recorded. RESULTS: Pearson correlation coefficients for FFDM, US, and CEDM vs histopathology were 0...
July 12, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28681390/a-deep-feature-fusion-methodology-for-breast-cancer-diagnosis-demonstrated-on-three-imaging-modality-datasets
#7
Natalia Antropova, Benjamin Q Huynh, Maryellen L Giger
BACKGROUND: Deep learning methods for radiomics/computer-aided diagnosis (CADx) are often prohibited by small datasets, long computation time, and the need for extensive image preprocessing. AIMS: We aim to develop a breast CADx methodology that addresses the aforementioned issues by exploiting the efficiency of pre-trained convolutional neural networks (CNNs) and using pre-existing handcrafted CADx features. MATERIALS & METHODS: We present a methodology that extracts and pools low- to mid-level features using a pretrained CNN and fuses them with handcrafted radiomic features computed using conventional CADx methods...
October 2017: Medical Physics
https://www.readbyqxmd.com/read/28609204/surveillance-of-women-with-the-brca1-or-brca2-mutation-by-using-biannual-automated-breast-us-mr-imaging-and-mammography
#8
Jan C M van Zelst, Roel D M Mus, Gwendolyn Woldringh, Matthieu J C M Rutten, Peter Bult, Suzan Vreemann, Mathijn de Jong, Nico Karssemeijer, Nicoline Hoogerbrugge, Ritse M Mann
Purpose To evaluate a multimodal surveillance regimen including yearly full-field digital (FFD) mammography, dynamic contrast agent-enhanced (DCE) magnetic resonance (MR) imaging, and biannual automated breast (AB) ultrasonography (US) in women with BRCA1 and BRCA2 mutations. Materials and Methods This prospective multicenter trial enrolled 296 carriers of the BRCA mutation (153 BRCA1 and 128 BRCA2 carriers, and 15 women with first-degree untested relatives) between September 2010 and November 2012, with follow-up until November 2015...
November 2017: Radiology
https://www.readbyqxmd.com/read/28549292/globally-supported-radial-basis-function-based-collocation-method-for-evolution-of-level-set-in-mass-segmentation-using-mammograms
#9
Kanchan Lata Kashyap, Manish Kumar Bajpai, Pritee Khanna
Computer-aided detection systems play an important role for the detection of breast abnormalities using mammograms. Global segmentation of mass in mammograms is a complex process due to low contrast mammogram images, irregular shape of mass, speculated margins, and the presence of intensity variations of pixels. This work presents a new approach for mass detection in mammograms, which is based on the variational level set function. Mesh-free based radial basis function (RBF) collocation approach is employed for the evolution of level set function for segmentation of breast as well as suspicious mass region...
August 1, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28543761/experimental-characterization-of-a-direct-conversion-amorphous-selenium-detector-with-thicker-conversion-layer-for-dual-energy-contrast-enhanced-breast-imaging
#10
David A Scaduto, Olivier Tousignant, Wei Zhao
PURPOSE: Dual-energy contrast-enhanced imaging is being investigated as a tool to identify and localize angiogenesis in the breast, a possible indicator of malignant tumors. This imaging technique requires that x-ray images are acquired at energies above the k-shell binding energy of an appropriate radiocontrast agent. Iodinated contrast agents are commonly used for vascular imaging, and require x-ray energies greater than 33 keV. Conventional direct conversion amorphous selenium (a-Se) flat-panel imagers for digital mammography show suboptimal absorption efficiencies at these higher energies...
August 2017: Medical Physics
https://www.readbyqxmd.com/read/28541197/high-energy-resolution-hyperspectral-x-ray-imaging-for-low-dose-contrast-enhanced-digital-mammography
#11
Silvia Pani, Sarene C Saifuddin, Filipa I M Ferreira, Nicholas Henthorn, Paul Seller, Paul J Sellin, Philipp Stratmann, Matthew C Veale, Matthew D Wilson, Robert J Cernik
Contrast-enhanced digital mammography (CEDM) is an alternative to conventional X-ray mammography for imaging dense breasts. However, conventional approaches to CEDM require a double exposure of the patient, implying higher dose, and risk of incorrect image registration due to motion artifacts. A novel approach is presented, based on hyperspectral imaging, where a detector combining positional and high-resolution spectral information (in this case based on Cadmium Telluride) is used. This allows simultaneous acquisition of the two images required for CEDM...
September 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28457521/image-processing-can-cause-some-malignant-soft-tissue-lesions-to-be-missed-in-digital-mammography-images
#12
L M Warren, M D Halling-Brown, P T Looney, D R Dance, M G Wallis, R M Given-Wilson, L Wilkinson, R McAvinchey, K C Young
AIM: To investigate the effect of image processing on cancer detection in mammography. METHODS AND MATERIALS: An observer study was performed using 349 digital mammography images of women with normal breasts, calcification clusters, or soft-tissue lesions including 191 subtle cancers. Images underwent two types of processing: FlavourA (standard) and FlavourB (added enhancement). Six observers located features in the breast they suspected to be cancerous (4,188 observations)...
September 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28379734/potential-cost-savings-of-contrast-enhanced-digital-mammography
#13
COMPARATIVE STUDY
Bhavika K Patel, Richard J Gray, Barbara A Pockaj
OBJECTIVE: The purpose of this article is to discuss whether the sensitivity and specificity of contrast-enhanced digital mammography (CEDM) render it a viable diagnostic alternative to breast MRI. CONCLUSION: That CEDM couples low-energy images (comparable to the diagnostic quality of standard mammography) and subtracted contrast-enhanced mammograms make it a cost-effective modality and a realistic substitute for the more costly breast MRI.
June 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28318506/assessment-of-disease-extent-on-contrast-enhanced-mri-in-breast-cancer-detected%C3%A2-at-digital-breast-tomosynthesis-versus%C3%A2-digital-mammography-alone
#14
COMPARATIVE STUDY
A V Chudgar, E F Conant, S P Weinstein, B M Keller, M Synnestvedt, P Yamartino, E S McDonald
AIM: To compare the utility of breast magnetic resonance imaging (MRI) in determining the extent of disease in patients with newly diagnosed breast cancer detected on combination digital breast tomosynthesis (DBT) versus digital screening mammography (DM). MATERIALS AND METHODS: Review of 24,563 DBT-screened patients and 10,751 DM-screened patients was performed. Two hundred and thirty-five DBT patients underwent subsequent MRI examinations; 82 to determine extent of disease after newly diagnosed breast cancer...
July 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28284000/a-method-for-microcalcifications-detection-in-breast-mammograms
#15
Abbas H Hassin Alasadi, Ahmed Kadem Hamed Al-Saedi
Breast cancer is the most cause of death for women above age 40 around the world. In this paper, we propose a method to detect microcalcifications in digital mammography images using two-dimensional Discrete Wavelets Transform and image enhancement techniques for removing noise as well as to get a better contrast. The initial step is applying a preprocessing techniques to improve the edge of the breast and then segmentation process (Region of interest) for eliminating some regions in the image, which are not useful for the mammography interpretation...
April 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28112559/breast-radiation-dose-with-cesm-compared-with-2d-ffdm-and-3d-tomosynthesis-mammography
#16
COMPARATIVE STUDY
Judy R James, William Pavlicek, James A Hanson, Thomas F Boltz, Bhavika K Patel
OBJECTIVE: We aimed to compare radiation dose received during contrast-enhanced spectral mammography (CESM) using high- and low-energy projections with radiation dose received during 2D full field digital mammography (FFDM) and 3D tomosynthesis on phantoms and patients with varying breast thickness and density. MATERIALS AND METHODS: A single left craniocaudal projection was chosen to determine the doses for 6214 patients who underwent 2D FFDM, 3662 patients who underwent 3D tomosynthesis, and 173 patients who underwent CESM in this retrospective study...
February 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28055247/staging-of-breast-cancer-and-the-advanced-applications-of-digital-mammogram-what-the-physician-needs-to-know
#17
Maha H Helal, Sahar M Mansour, Mai Zaglol, Lamia A Salaleldin, Omniya M Nada, Marwa A Haggag
OBJECTIVE: To study the role of advanced applications of digital mammogram, whether contrast-enhanced spectral mammography (CESM) or digital breast tomosynthesis (DBT), in the "T" staging of histologically proven breast cancer before planning for treatment management. METHODS: In this prospective analysis, we evaluated 98 proved malignant breast masses regarding their size, multiplicity and the presence of associated clusters of microcalcifications. Evaluation methods included digital mammography (DM), 3D tomosynthesis and CESM...
March 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28046698/mo-fg-campus-iep1-02-dose-reduction-in-contrast-enhanced-digital-mammography-using-a-photon-counting-detector
#18
S Lee, S Kang, J Eom
PURPOSE: Photon-counting detectors (PCDs) allow multi-energy X-ray imaging without additional exposures and spectral overlap. This capability results in the improvement of accuracy of material decomposition for dual-energy X-ray imaging and the reduction of radiation dose. In this study, the PCD-based contrast-enhanced dual-energy mammography (CEDM) was compared with the conventional CDEM in terms of radiation dose, image quality and accuracy of material decomposition. METHODS: A dual-energy model was designed by using Beer-Lambert's law and rational inverse fitting function for decomposing materials from a polychromatic X-ray source...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28044312/optimization-of-contrast-enhanced-breast-imaging-analysis-using-a-cascaded-linear-system-model
#19
Yue-Houng Hu, David A Scaduto, Wei Zhao
PURPOSE: Contrast-enhanced (CE) breast imaging involves the injection contrast agents (i.e., iodine) to increase conspicuity of malignant lesions. CE imaging may be used in conjunction with digital mammography (DM) or digital breast tomosynthesis (DBT) and has shown promise in improving diagnostic specificity. Both CE-DM and CE-DBT techniques require optimization as clinical diagnostic tools. Physical factors including x-ray spectra, subtraction technique, and the signal from iodine contrast, must be considered to provide the greatest object detectability and image quality...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/27896471/contrast-enhanced-spectral-mammography-vs-mammography-and-mri-clinical-performance-in-a-multi-reader-evaluation
#20
Eva M Fallenberg, Florian F Schmitzberger, Heba Amer, Barbara Ingold-Heppner, Corinne Balleyguier, Felix Diekmann, Florian Engelken, Ritse M Mann, Diane M Renz, Ulrich Bick, Bernd Hamm, Clarisse Dromain
OBJECTIVES: To compare the diagnostic performance of contrast-enhanced spectral mammography (CESM) to digital mammography (MG) and magnetic resonance imaging (MRI) in a prospective two-centre, multi-reader study. METHODS: One hundred seventy-eight women (mean age 53 years) with invasive breast cancer and/or DCIS were included after ethics board approval. MG, CESM and CESM + MG were evaluated by three blinded radiologists based on amended ACR BI-RADS criteria...
July 2017: European Radiology
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