Silvano Gallus, Alessandra Lugo, Elisa Borroni, Teo Vignoli, Lisa Lungaro, Giacomo Caio, Roberto De Giorgio, Giorgio Zolic, Fabio Caputoc
BACKGROUND: Alcohol Withdrawal Syndrome (AWS) is characterized by different phases (acute, early and protracted). Protracted alcohol withdrawal (PAW) presents some symptoms, which may persist for several weeks, months or even years after drinking cessation. METHODS: We conducted a systematic review of the literature in major scientific databases on selected AWS symptoms (craving, sleep disorders, and anhedonia) in patients with alcohol use disorder. RESULTS: Of the 102 eligible publications (70 RCTs and 32 cohort studies), 88 provided data on craving, 21 on sleep disorders, and 1 on anhedonia...
July 6, 2022: Current Neuropharmacology