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https://www.readbyqxmd.com/read/29454105/assessing-the-repeatability-of-absolute-cmro-2-oef-and-haemodynamic-measurements-from-calibrated-fmri
#1
Alberto Merola, Michael A Germuska, Kevin Murphy, Richard G Wise
As energy metabolism in the brain is largely oxidative, the measurement of cerebral metabolic rate of oxygen consumption (CMRO 2 ) is a desirable biomarker for quantifying brain activity and tissue viability. Currently, PET techniques based on oxygen isotopes are the gold standard for obtaining whole brain CMRO 2 maps. Among MRI techniques that have been developed as an alternative are dual calibrated fMRI (dcFMRI) methods, which exploit simultaneous measurements of BOLD and ASL signals during a hypercapnic-hyperoxic experiment to modulate brain blood flow and oxygenation...
February 14, 2018: NeuroImage
https://www.readbyqxmd.com/read/29452741/magic-angle-in-cardiac-ct-eliminating-clinically-relevant-metal-artifacts-in-pacemaker-leads-with-a-lead-tip-gantry-angle-of-%C3%A2-70%C3%A2
#2
Sebastian D Reinartz, Christiane K Kuhl, Kerstin Fehrenbacher, Andreas Napp
RATIONALE AND OBJECTIVE: To identify the influence of various parameters for reducing artifacts in computed tomography (CT) of commonly used pacemakers or implantable cardioverter-defibrillator (ICD) lead tips. MATERIALS AND METHODS: This ex vivo phantom study compared two CT techniques (Dual-Energy CT [DECT] vs. Dual-Source CT [DSCT]), as well as the influence of incremental alterations of current-time product and pacemaker lead-tip angle with respect to the gantry plane...
February 13, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29450584/dietary-patterns-and-longitudinal-change-in-hip-bone-mineral-density-among-older-men
#3
T S Rogers, S Harrison, S Judd, E S Orwoll, L M Marshall, J Shannon, L Langsetmo, N E Lane, J M Shikany
Studying dietary patterns is often more informative than individual nutrients or foods. We found that a Prudent dietary pattern (rich in vegetables and fish) was associated with reduced loss of total hip BMD in older men. A Prudent dietary pattern may be a potential lifestyle strategy for minimizing bone loss. INTRODUCTION: This study aimed to identify baseline dietary patterns using factor analysis in a cohort of older men and to evaluate whether the dietary patterns were associated with bone mineral density change (%ΔBMD) at the total hip and femoral neck over time...
February 15, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29449014/periarticular-bone-predicts-knee-osteoarthritis-progression-data-from-the-osteoarthritis-initiative
#4
Grace H Lo, Erika Schneider, Jeffrey B Driban, Lori Lyn Price, David J Hunter, Charles B Eaton, Marc C Hochberg, Rebecca D Jackson, C Kent Kwoh, Michael C Nevitt, John A Lynch, Timothy E McAlindon
OBJECTIVE: Osteoarthritis (OA) is a disease with a substantial public health burden. Quantitative assessments of periarticular bone may be a biomarker capable of monitoring early disease progression. The purpose of this study was to evaluate whether measures of periarticular bone associate with longitudinal structural progression. METHODS: We conducted a 12-18 months longitudinal study using the Osteoarthritis Initiative (OAI). Participants received knee dual-energy x-ray absorptiometry (DXA), trabecular magnetic resonance (MR) imaging, and x-rays...
January 31, 2018: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/29447485/should-women-be-screened-for-osteoporosis-at-midlife
#5
T J de Villiers
Osteoporosis and associated fractures are common in women after midlife and will increase as the population ages. Osteoporosis-related fractures cause a significant increase in morbidity and mortality. Osteoporosis decreases the quality of life and productivity of many older women, with an increasing burden on health-care resources. Future risk of fracture can be managed by evidence-based interventions. It is thus appropriate to estimate the future risk of fracture in all women at the age of 50 years or at menopause, whichever occurs first...
February 15, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/29446668/improved-opacification-of-a-suboptimally-enhanced-pulmonary-artery-in-chest-ct-experience-using-a-dual-layer-detector-spectral-ct
#6
Kyungsoo Bae, Kyung Nyeo Jeon, Soo Buem Cho, Sung Eun Park, Jin Il Moon, Hye Jin Baek, Bo Hwa Choi
OBJECTIVE: The objective of our study was to evaluate the quality of virtual monoenergetic imaging (VMI) from dual-layer detector spectral CT and the effect of virtual monoenergetic images obtained at low energies on the detection of pulmonary embolism (PE) in patients with a suboptimally enhanced pulmonary artery on chest CT. MATERIALS AND METHODS: Of 1552 consecutive chest CT examinations performed with dual-layer detector spectral CT using a routine protocol with a tube voltage of 120 kVp, 79 examinations with suboptimal enhancement of the pulmonary artery (i...
February 15, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29446319/dual-energy-ct-iodine-maps-as-an-alternative-quantitative-imaging-biomarker-to-abdominal-ct-perfusion-determination-of-appropriate-trigger-delays-for-acquisition-using-bolus-tracking
#7
Stephan Skornitzke, Franziska Fritz, Philipp Mayer, Marco Koell, Jens Hansen, Gregor Pahn, Thilo Hackert, Hans-Ulrich Kauczor, Wolfram Stiller
OBJECTIVE: Quantitative evaluation of different bolus-tracking trigger delays for acquisition of dual-energy (DE) computed tomography (CT) iodine maps as an alternative to CT perfusion. METHODS: Prior to this retrospective analysis of prospectively acquired data, DECT perfusion sequences were dynamically acquired in 22 patients with pancreatic carcinoma using dual-source CT at 80/140kV p with tin filtration. After deformable motion-correction, perfusion maps of blood flow (BF) were calculated from 80kVp image series of DECT, and iodine maps were calculated for each of the 34 DECT acquisitions per patient...
February 15, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29446082/development-of-a-dual-energy-computed-tomography-quality-control-program-characterization-of-scanner-response-and-definition-of-relevant-parameters-for-a-fast-kvp-switching-dect-system
#8
Jessica L Nute, Megan C Jacobsen, Wolfgang Stefan, Wei Wei, Dianna D Cody
PURPOSE: A prototype QC phantom system and analysis process were developed to characterize the spectral capabilities of a fast kV-switching dual-energy computed tomography (DECT) scanner. This work addresses the current lack of quantitative oversight for this technology, with the goal of identifying relevant scan parameters and test metrics instrumental to the development of a dual-energy quality control (DEQC). METHODS: A prototype elliptical phantom (effective diameter: 35 cm) was designed with multiple material inserts for DECT imaging...
February 15, 2018: Medical Physics
https://www.readbyqxmd.com/read/29445830/bone-health-assessment-in-older-people-with-or-without-muscle-health-impairment
#9
M Locquet, C Beaudart, O Bruyère, J A Kanis, L Delandsheere, J-Y Reginster
This study investigated the relationship between muscle and bone status in elderly individuals. Our results suggested links between sarcopenia and osteoporosis; impairment in muscle status (i.e., muscle mass, muscle strength, and physical performance) is associated with deterioration in bone mass and texture subsequently leading to an increased risk of fracture. INTRODUCTION: Accumulating evidence has shown associations between sarcopenia and osteoporosis, but existing studies face inconsistencies in the clinical definition of both conditions...
February 14, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29444956/dual-color-metal-induced-and-f%C3%A3-rster-resonance-energy-transfer-for-cell-nanoscopy
#10
Anna M Chizhik, Carina Wollnik, Daja Ruhlandt, Narain Karedla, Alexey I Chizhik, Lara Hauke, Dirk Hähnel, Ingo Gregor, Jörg Enderlein, Florian Rehfeldt
We report a novel method, dual color axial nanometric localization by Metal Induced Energy Transfer (dcMIET), and combine it with Förster Resonant Energy Transfer (FRET) for resolving structural details in cells on the molecular level. We demonstrate the capability of this method on cytoskeletal elements and adhesions in human mesenchymal stem cells (hMSCs). Our approach is based on Fluorescence-Lifetime-Imaging Microscopy (FLIM), and allows for precise determination of the 3D architecture of stress fibers anchoring at focal adhesions, thus yielding crucial information to understand cell-matrix mechanics...
February 14, 2018: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/29444811/clinical-usefulness-of-dual-energy-cardiac-computed-tomography-in-acute-coronary-syndrome-using-a-dual-layer-spectral-detector-scanner
#11
Taiki Nishihara, Seitaro Oda, Daisuke Sueta, Yasuhiro Izumiya, Koichi Kaikita, Kenichi Tsujita, Daisuke Utsunomiya, Takeshi Nakaura, Yasuyuki Yamashita
No abstract text is available yet for this article.
February 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29444618/pathophysiology-of-drug-induced-weight-and-metabolic-effects-findings-from-an-rct-in-healthy-volunteers-treated-with-olanzapine-iloperidone-or-placebo
#12
Jacob S Ballon, Utpal B Pajvani, Laurel Es Mayer, Zachary Freyberg, Robin Freyberg, Ignacio Contreras, Michael Rosenbaum, Rudolph L Leibel, Jeffrey A Lieberman
Second generation antipsychotics are prescribed for an increasing number of psychiatric conditions, despite variable associations with weight gain, dyslipidemia, and impaired glucose tolerance. The mechanism(s) of the apparent causal relationships between these medications and metabolic effects have been inadequately defined and are potentially confounded by genetic risk of mental illness, attendant lifestyle, and concomitant medications. Therefore, we conducted a study in which 24 healthy volunteers were randomized to olanzapine (highly weight-gain liability), iloperidone (less weight-gain liability), or placebo treatment for 28 days under double-blind conditions...
February 1, 2018: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/29444114/childhood-obesity-treatment-effects-on-bmi-sds-body-composition-and-fasting-plasma-lipid-concentrations
#13
Tenna Ruest Haarmark Nielsen, Cilius Esmann Fonvig, Maria Dahl, Pernille Maria Mollerup, Ulrik Lausten-Thomsen, Oluf Pedersen, Torben Hansen, Jens-Christian Holm
OBJECTIVE: The body mass index (BMI) standard deviation score (SDS) may not adequately reflect changes in fat mass during childhood obesity treatment. This study aimed to investigate associations between BMI SDS, body composition, and fasting plasma lipid concentrations at baseline and during childhood obesity treatment. METHODS: 876 children and adolescents (498 girls) with overweight/obesity, median age 11.2 years (range 1.6-21.7), and median BMI SDS 2.8 (range 1...
2018: PloS One
https://www.readbyqxmd.com/read/29443867/effects-of-whole-body-vibration-versus-pilates-exercise-on-bone-mineral-density-in-postmenopausal-women-a-randomized-and-controlled-clinical-trial
#14
Laís Campos de Oliveira, Raphael Gonçalves de Oliveira, Deise Aparecida de Almeida Pires-Oliveira
BACKGROUND AND PURPOSE: Decreased bone mineral density (BMD) is a common condition in postmenopausal women that can be managed with impact activities. Among the activities studied are the whole-body vibration (WBV) and muscle-strengthening exercises. The purpose of this study was to compare the effects of WBV versus Pilates exercise on BMD in postmenopausal women. METHODS: In this study, 51 postmenopausal women were randomized into 3 groups: vibration (n = 17), Pilates (n = 17), and control (n = 17)...
February 12, 2018: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/29443079/gene-regulation-and-targeted-therapy-in-gastric-cancer-peritoneal-metastasis-radiological-findings-from-dual-energy-ct-and-pet-ct
#15
Bowen Shi, Huimin Lin, Miao Zhang, Wei Lu, Ying Qu, Huan Zhang
Gastric cancer remains fourth in cancer incidence worldwide with a five-year survival of only 20%-30%. Peritoneal metastasis is the most frequent type of metastasis that accompanies unresectable gastric cancer and is a definitive determinant of prognosis. Preventing and controlling the development of peritoneal metastasis could play a role in helping to prolong the survival of gastric cancer patients. A non-invasive and efficient imaging technique will help us to identify the invasion and metastasis process of peritoneal metastasis and to monitor the changes in tumor nodules in response to treatments...
January 22, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29443044/scanning-skeletal-remains-for-bone-mineral-density-in-forensic-contexts
#16
Amanda R Hale, Ann H Ross
The purpose of this paper is to introduce a promising, novel method to aid in the assessment of bone quality in forensically relevant skeletal remains. BMD is an important component of bone's nutritional status and in skeletal remains of both juveniles and adults, and it can provide information about bone quality. For adults remains, it can provide information on pathological conditions or when bone insufficiency may have occurred. In juveniles, it provides a useful metric to elucidate cases of fatal starvation or neglect, which are generally difficult to identify...
January 29, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29442916/facile-synthesis-and-high-activity-of-novel-composite-c-fe-bivo%C3%A2-photocatalyst-for-degradation-of-cipfloxacin
#17
Shijie Chen, Xunan Zhai, Yingjie Li, Jinlong Li, Renjiang Lü, Peng Wang, Xiaojun Tang, Xi Chen, Lidi Gao
A novel C/Fe-BiVO4 nanosheet composite photocatalyst combining the properties of both semiconductor and Fenton like catalyst was prepared via a two-step method involving Resin carbonization and hydrothermal process. The samples were characterized by X-ray diffraction (XRD), scanning electronic microscopy (SEM) and energy dispersive spectroscopy (EDS), transmission electron microscopy (TEM), UV-vis diffuse reflectance spectra (DRS), X-ray photoelectron spectroscopy (XPS), Fourier transformed infrared spectroscopy (FT-IR) and nitrogen adsorption-desorption measurements and fluorescence spectrum technique...
April 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442745/-okra-abelmoschus-esculentus-plant-extract-assisted-combustion-synthesis-and-characterization-studies-of-spinel-znal%C3%A2-o%C3%A2-nano-catalysts
#18
P Bhavani, A Manikandan, P Paulraj, A Dinesh, M Durka, S Arul Antony
Spinel ZnAl2O4 nano-catalysts were synthesized by a simple, economical and eco-friendly microwave irradiation (MIM) and conventional heating methods (CHM), using metal nitrates and Okra (Abelmoschus esculentus) plant extract, which play a dual role of both oxidizing and reducing nature. Powder X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, energy dispersive X-ray (EDX) and selected area electron diffraction (SAED) pattern results were confirmed that the samples have a single-phase cubic spinel structure with high crystalline nature of ZnAl2O4...
June 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442150/ultrasound-scans-and-dual-energy-ct-identify-tendons-as-preferred-anatomical-location-of-msu-crystal-depositions-in-gouty-joints
#19
Yuan Yuan, Chang Liu, Xi Xiang, Tong-Ling Yuan, Li Qiu, Yi Liu, Yu-Bin Luo, Y Zhao, Martin Herrmann
OBJECTIVE: The present study was performed to localize the articular deposition of monosodium urate (MSU) crystal in joints. We compare the detection efficiencies of dual-energy CT (DECT) and ultrasound scans. METHODS: Analyses by DECT and ultrasound were performed with 184 bilateral joints of the lower limbs of 54 consecutive gout patients. All joints were categorized into (1) knee, (2) ankle, (3) MTP1, and (4) MTP2, and sorted into those with and those without detectable MSU deposition...
February 13, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29440880/comparison-of-three-tools-for-predicting-primary-osteoporosis-in-an-elderly-male-population-in-beijing-a-cross-sectional-study
#20
XiaoDong Zhang, JiSheng Lin, Yong Yang, Hao Wu, Yongjin Li, Xiuquan Yang, Qi Fei
Purpose: In this cross-sectional study, three clinical tools, the Osteoporosis Self-Assessment Tool for Asians (OSTA), Fracture Risk Assessment Tool (FRAX) without bone mineral density (BMD), and body mass index (BMI), for predicting primary osteoporosis (OP) were compared and ideal thresholds for omission of screening BMD were proposed in a community-dwelling elderly Han Beijing male population. Patients and methods: A total of 1,349 community-dwelling elderly Han Beijing males aged ≥50 years were enrolled in this study...
2018: Clinical Interventions in Aging
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