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https://www.readbyqxmd.com/read/28340152/sarcopenia-and-relationships-between-muscle-mass-measured-glomerular-filtration-rate-and-physical-function-in-patients-with-chronic-kidney-disease-stages-3-5
#1
Yunan Zhou, Matthias Hellberg, Philippa Svensson, Peter Höglund, Naomi Clyne
Background.: Sarcopenia and poor physical function are common in patients with chronic kidney disease (CKD). Our aim was to investigate the relationships between muscle mass and measured glomerular filtration rate (GFR) and between muscle mass and strength and balance, respectively, in patients with CKD stages 3-5. Methods.: This is a baseline data analysis of a randomized controlled clinical trial. A total of 148 adult patients with an estimated GFR <30 mL/min/1...
March 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28338579/correlative-analysis-of-vertebral-trabecular-bone-microarchitecture-and-mechanical-properties-a-combined-ultra-high-field-7-tesla-mri-and-biomechanical-investigation
#2
Daphne Guenoun, Alexandre Fouré, Martine Pithioux, Sandrine Guis, Thomas Le Corroller, Jean-Pierre Mattei, Vanessa Pauly, Maxime Guye, Monique Bernard, Patrick Chabrand, Pierre Champsaur, David Bendahan
STUDY DESIGN: High resolution imaging and biomechanical investigation of ex-vivo vertebrae OBJECTIVE.: To assess bone microarchitecture of cadaveric vertebrae using ultra-high field (UHF) 7 Tesla magnetic resonance imaging (MRI) and to determine whether the corresponding microarchitecture parameters were related to BMD and bone strength assessed by dual energy X-ray absorptiometry (DXA) and mechanical compression tests. SUMMARY OF BACKGROUND DATA: Limitations of DXA for the assessment of bone fragility and osteoporosis have been recognized and criteria of microarchitecture alteration have been included in the definition of osteoporosis...
March 23, 2017: Spine
https://www.readbyqxmd.com/read/28338536/dual-energy-computed-tomography-for-the-evaluation-of-enhancement-of-pulmonary-nodules%C3%A2-3-cm-in-size
#3
Michael J Reiter, Weston T Winkler, Kenton E Kagy, Ryan B Schwope, Christopher J Lisanti
PURPOSE: The aim of the study was to compare the accuracies of 4 different methods of assessing pulmonary nodule enhancement to distinguish benign from malignant solid pulmonary nodules using nondynamic contrast-enhanced dual-energy computed tomography. MATERIALS AND METHODS: Seventy-two patients (mean age, 62 y) underwent dual-energy chest computed tomography 3 minutes after intravenous contrast administration. Each of 118 pulmonary nodules (9±5.9 mm) were evaluated for enhancement by 4 methods: visual assessment, 3-dimensional automated postprocessing measurement tool, manually drawn region of interest with calculated iodine-related attenuation, and measurement of iodine concentration...
March 22, 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28338379/head-neck-trunk-and-pelvis-tissue-mass-predictions-for-young-adults-using-anthropometric-measures-and-dxa
#4
Danielle L Gyemi, Charles Kahelin, Nicole C George, David M Andrews
Accurate prediction of wobbling mass (WM), fat mass (FM), lean mass (LM) and bone mineral content (BMC) of living people using regression equations developed from anthropometric measures (lengths, circumferences, breadths, skinfolds) has previously been reported, but only for the extremities. Multiple linear stepwise regression was used to generate comparable equations for the head, neck, trunk and pelvis of young adults (38 males, 38 females). Equations were validated using actual tissue masses from an independent sample of 13 males and 13 females by manually segmenting full body Dual-energy X-ray Absorptiometry scans...
March 24, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/28338296/photochromism-and-dual-color-fluorescence-in-a-polyoxometalate-benzospiropyran-molecular-switch
#5
Arnaud Parrot, Aurélie Bernard, Aurélie Jacquart, Stefano Artin Serapian, Carles Bo, Etienne Derat, Olivier Oms, Anne Dolbecq, Anna Proust, Rémi Métivier, Pierre Mialane, Guillaume Izzet
The photophysical properties of a Keggin-type polyoxometalate (POM) covalently bounded to a benzospiropyran (BSPR) unit have been investigated. These studies reveal that both closed and open forms are emissive with distinct spectral features (λem (closed form)=530 nm, λem (open form)=670 nm) and that the fluorescence of the BSPR unit of the hybrid is considerably enhanced compared to BSPR parent compounds. While the fluorescence excitation energy of the BSPR reference compounds (370 nm) is close to the intense absorption responsible of the photochromic character (350 nm), the fluorescence excitation of the hybrid is shifted to lower energy (400 nm), improving the population of the emissive state...
March 24, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28338071/phase-transition-nanodroplets-for-real-time-photoacoustic-ultrasound-dual-modality-imaging-and-photothermal-therapy-of-sentinel-lymph-node-in-breast-cancer
#6
Lu Yang, Juan Cheng, Yuli Chen, Shengjie Yu, Fengqiu Liu, Yang Sun, Yu Chen, Haitao Ran
Pathological status of lymph nodes (LNs) plays a critical role in staging and treatment for the patients with breast cancer. Sentinel lymph node biopsy has become the standard method in determining pathological status of axillary LNs. Therefore, the determination of sentinel lymph nodes (SLNs) and therapy of metastatic LNs are highly desirable in clinic. Herein, an unprecedented carbon nanoparticles (CNs)-incorporated liquid-gas phase-transition nanodroplets (CNPs) with strong near-infrared (NIR) absorption, good biocompatibility, excellent photoacoustic (PA) and ultrasound (US) contrast, and high photothermal-conversion efficiency are reported in this study...
March 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28332393/amino-silane-as-a-molecular-linker-between-electron-transport-layer-and-active-layer-for-the-efficient-inverted-polymer-solar-cells
#7
Ping Fu, Xin Guo, Shengyang Wang, Yun Ye, Can Li
We presented an amino-silane as a molecular linker between ZnO electron transport layer and fullerene-based active layer for efficient inverted polymer solar cells. An enhanced power conversion efficiency (PCE) was obtained from 8.47% to 9.46% based on PTB7-Th as donors. The amino-silane molecular linker provides dual functionalities for enhanced PCE, including 1) passivating ZnO surface and decreasing the surface work function of ZnO for energy level alignment; 2) bonding onto the fullerene-based active layer to reduce the interface contact resistance...
March 23, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28332199/investigating-the-feasibility-of-classifying-breast-microcalcifications-using-photon-counting-spectral-mammography-a-simulation-study
#8
Bahaa Ghammraoui, Stephen J Glick
PURPOSE: A dual-energy material decomposition method using photon-counting spectral mammography was investigated as a non-invasive diagnostic approach to differentiate between Type I calcifications, consisting of calcium oxalate dihydrate or weddellite compounds that are more often associated with benign lesions, and Type II calcifications containing hydroxyapatite that are predominantly associated with malignant tumors. METHODS: The study was carried out by numerical simulation to assess the feasibility of the proposed approach...
March 22, 2017: Medical Physics
https://www.readbyqxmd.com/read/28332172/quantitative-ultrasound-and-dxa-measurements-in-aromatase-inhibitor-treated-breast-cancer-women-receiving-denosumab
#9
A Catalano, A Gaudio, N Morabito, G Basile, R M Agostino, A Xourafa, M Atteritano, E Morini, G Natale, A Lasco
PURPOSE: Denosumab has been proven to reduce fracture risk in breast cancer (BC) women under aromatase inhibitors (AIs). Quantitative ultrasound (QUS) provides information on the structure and elastic properties of bone. Our aim was to assess bone health by phalangeal QUS and by dual-energy X-ray absorptiometry (DXA), and to evaluate bone turnover in AIs-treated BC women receiving denosumab. METHODS: 35 Postmenopausal BC women on AIs were recruited (mean age 61...
March 22, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28331906/associations-between-sarcopenia-and-degenerative-lumbar-scoliosis-in-older-women
#10
Yawara Eguchi, Munetaka Suzuki, Hajime Yamanaka, Hiroshi Tamai, Tatsuya Kobayashi, Sumihisa Orita, Kazuyo Yamauchi, Miyako Suzuki, Kazuhide Inage, Kazuki Fujimoto, Hirohito Kanamoto, Koki Abe, Yasuchika Aoki, Tomoaki Toyone, Tomoyuki Ozawa, Kazuhisa Takahashi, Seiji Ohtori
BACKGROUND: Age-related sarcopenia can cause various forms of physical disabilities. We investigated how sarcopenia affects degenerative lumbar scoliosis (DLS) and lumbar spinal canal stenosis (LSCS). METHODS: Subjects comprised 40 elderly women (mean age 74 years) with spinal disease whose chief complaints were low back pain and lower limb pain. They included 15 cases of DLS (mean 74.8 years) and 25 cases of LSCS (mean age 72.9 years). We performed whole-body dual-energy X-ray absorptiometry (DXA) to analyze body composition, including appendicular and trunk skeletal muscle mass index (SMI; lean mass (kg)/height (m)(2)) and bone mineral density (BMD)...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28331192/pd-zno-nanorods-based-sensor-for-highly-selective-detection-of-extremely-low-concentration-hydrogen
#11
Mohit Kumar, Vijendra Singh Bhati, Sapana Ranwa, Jitendra Singh, Mahesh Kumar
We report highly hydrogen selective Pd contacted ZnO nanorods based sensor detecting low concentration even at low operating temperature of 50 °C. The sensor performance was investigated for various gases such as H2, CH4, H2S and CO2 at different operating temperatures from 50 °C to 175 °C for various gas concentrations ranging from 7 ppm to 10,000 ppm (1%). The sensor is highly efficient as it detects hydrogen even at low concentration of ~7 ppm and at operating temperature of 50 °C. The sensor's minimum limit of detection and relative response at 175 °C were found 7 ppm with ~38...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28330686/imaging-of-acute-and-chronic-thromboembolic-disease-state-of-the-art
#12
REVIEW
A Ruggiero, N J Screaton
Acute pulmonary embolism (PE) is a life-threatening condition that requires prompt diagnosis and treatment. Recent advances in imaging allow acute and rapid recognition even by the non-specialist radiologist. Most acute emboli resolve on anticoagulation without sequelae; however, some emboli fail to fully resolve becoming endothelialised with the development of chronic thromboembolic disease (CTED). Increased pulmonary vascular resistance arising from CTED may lead to chronic thromboembolic pulmonary hypertension (CTEPH) a debilitating disease affecting up to 5% of survivors of acute PE...
March 19, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28329121/very-low-calorie-diets-for-weight-loss-in-obese-older-adults-a-randomized-trial
#13
Cilla J Haywood, Luke A Prendergast, Katrina Purcell, Lauren Le Fevre, Wen Kwang Lim, Mary Galea, Joseph Proietto
Background: Obesity contributes to disability in older adults, and this is offset by weight loss and exercise. Very Low Calorie Diets (VLCDs) achieve rapid weight loss; however, these have not been rigorously evaluated in older people. Methods: A randomized trial was conducted from August 2012 through December 2015. The intervention was 12 weeks of thrice weekly exercise combined with either healthy eating advice (Ex/HE), hypocaloric diet (Ex/Diet), or VLCD (Ex/VLCD)...
February 20, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28328712/resistance-training-induced-elevations-in-muscular-strength-in-trained-men-are-maintained-after-2-weeks-of-detraining-and-not-differentially-affected-by-whey-protein-supplementation
#14
Paul S Hwang, Thomas L Andre, Sarah K McKinley-Barnard, Flor E Morales Marroquín, Joshua J Gann, Joon J Song, Darryn S Willoughby
Hwang, PS, Andre, TL, McKinley-Barnard, SK, Morales Marroquín, FE, Gann, JJ, Song, JJ, and Willoughby, DS. Resistance training-induced elevations in muscular strength in trained men are maintained after 2 weeks of detraining and not differentially affected by whey protein supplementation. J Strength Cond Res 31(4): 869-881, 2017-Resistance training (RT) with nutritional strategies incorporating whey protein intake postexercise can stimulate muscle protein synthesis and elicit hypertrophy. The early phases of training-induced anabolic responses can be attenuated with longer-term training...
April 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28328530/imaging-methods-for-bone-mass-evaluation-during-childhood-and-adolescence-an-update
#15
Isabela Leite Pezzuti, Adriana Maria Kakehasi, Maria Tereza Filgueiras, Juliana Albano de Guimarães, Isabela Alves Campos de Lacerda, Ivani Novato Silva
The objective of the work was to prepare an update on imaging methods for bone evaluation during childhood and adolescence. The text was based on original and review articles on imaging methods for clinical evaluation of bone mass in children and adolescents up to 20 years old. They were selected from BIREME and PUBMED by means of the following keywords: bone density; osteoporosis/diagnosis; densitometry; tomography; ultrasonography; magnetic resonance imaging; and radiogrammetry and published in Portuguese or English, in the last 10 years (2006-2016)...
March 22, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28328200/fluorescence-resonance-energy-transfer-based-dna-tetrahedron-nano-tweezer-for-highly-reliable-detection-of-tumor-related-mrna-in-living-cells
#16
Lei He, Dan-Qing Lu, Hao Liang, Sitao Xie, Can Luo, Miaomiao Hu, Liujun Xu, Xiaobing Zhang, Weihong Tan
Accurate detection and imaging of tumor-related mRNA in living cells hold great promise for early cancer detection. However, currently, most probes designed to image intracellular mRNA confront intrinsic interferences arising from complex biological matrices and resulting in inevitable false-positive signals. To circumvent this problem, a new class of intracellular DNA nanoprobe, termed DNA tetrahedron nano-tweezer (DTNT), was developed to reliably image tumor-related mRNA in living cells based on the FRET (fluorescence resonance energy transfer) "off" to "on" signal readout mode...
March 22, 2017: ACS Nano
https://www.readbyqxmd.com/read/28327109/a-cross-sectional-study-on-sarcopenia-using-different-methods-reference-values-for-healthy-saudi-young-men
#17
Shaea A Alkahtani
BACKGROUND: The aim of this study was to determine reference values for sarcopenia indices using different methods in healthy Saudi young men. METHODS: Participants included 232 Saudi men aged between 20 and 35 years. The study measured anthropometric indices, blood pressure, hand grip strength, and lean muscle mass using dual-energy X-ray absorptiometry (DXA), and bioelectrical impedance analysis (BIA) was performed using Inbody 770 and Tanita 980 devices. RESULTS: Using DXA, the mean value of appendicular lean mass divided by the height squared (ALM/ht(2)) was found to be 8...
March 21, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28326794/urothelial-tumors-and-dual-band-imaging-a-new-concept-in-confocal-laser-endomicroscopy
#18
Arnaud Marien, Aurélien Rock, Khaled El Maadarani, Catherine Francois, Pierre Gosset, Brigitte Mauroy, Jean-Louis Bonnal
OBJECTIVES: Confocal laser endomicroscopy (CLE) uses a low-energy laser light source to obtain microscopic histology images of bladder tissue exposed to a fluorescent dye. To evaluate the feasibility of using CLE with two fluorophores: fluorescein (FLUO) and hexylaminolevulinate (HAL) to determine histologic and cytologic bladder cancer criteria. METHODS: Patients eligible for HAL-photodynamic diagnosis-assisted transurethral resection of bladder tumor were included...
March 22, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28326726/-effects-of-different-surface-modifications-on-micro-structure-and-adhesion-of-zirconia-ceramic-an-in-vitro-study
#19
Li Siwen, Li Shishi, Wang Yanhong, Ma Hongmei
OBJECTIVE: This study evaluated the effect of different mechanical-chemical surface treatments on the characteristics, microstructure, and composition of zirconia ceramics and on the zirconia-dentin adhesion. METHODS: The sintered commercial zirconia blocks (IPS e.max ZirCAD) were sectioned into 126 beams (6 mm×6 mm×5 mm) and randomly assigned to seven experimental groups (n=18). The zirconia block specimens were further treated as follows: (A) untreated, as control; (B) sandblasted with 50 μm Al2O3; (C) sandblasted with 50 μm Al2O3+30 μm silica powder; (D) sandblasted with 50 μm Al2O3+30% silica-sol coating; (E) sandblasted with 110 μm Al2O3; (F) sandblasted with 110 μm Al2O3+30 μm silica powder; and (G) sandblasted with 110 μm Al2O3+30% silica-sol coating...
February 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28326351/effects-of-low-dose-ibuprofen-supplementation-and-resistance-training-on-bone-and-muscle-in-postmenopausal-women-a-randomized-controlled-trial
#20
Whitney R D Duff, Saija A Kontulainen, Darren G Candow, Julianne J Gordon, Riley S Mason, Regina Taylor-Gjevre, Bindu Nair, Michael Szafron, Adam D G Baxter-Jones, Gordon A Zello, Philip D Chilibeck
PURPOSE: To compare the effects of nine months of exercise training and ibuprofen supplementation (given immeditately after exercise sessions) on bone and muscle in postmenopausal women. METHODS: In a double-blind randomized trial, participants (females: n = 90, mean age 64.8, SD 4.3 years) were assigned (computer generated, double blind) to receive supervised resistance training or stretching 3 days/week, and ibuprofen (400 mg, post-exercise) or placebo (i...
December 2016: Bone Reports
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