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multivitamins and mortality

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https://www.readbyqxmd.com/read/28877128/antioxidant-and-trace-element-supplementation-reduce-the-inflammatory-response-in-critically-ill-burn-patients
#1
Sarah Rehou, Shahriar Shahrokhi, Rimona Natanson, Mile Stanojcic, Marc G Jeschke
Oxidative stress after burn injury induces inflammatory and hypermetabolic responses associated with adverse outcomes. We propose that antioxidant and trace element supplementation may reduce oxidative stress and subsequently alleviate inflammation and hypermetabolism, thus improving clinical outcomes. We conducted a cohort study of adult patients with an acute burn injury admitted to our provincial burn center. Patients in the antioxidant group received an intravenous infusion of multivitamins and trace elements for the first 14 days after admission...
August 31, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28758316/multivitamin-use-and-risk-of-stroke-incidence-and-mortality-amongst-women
#2
S N Adebamowo, D Feskanich, M Stampfer, K Rexrode, W C Willett
BACKGROUND AND PURPOSE: Few studies have examined the association between multivitamin use and the risk of stroke incidence and mortality, and the results remain inconclusive as to whether multivitamins are beneficial. METHODS: The associations between multivitamin use and the risk of incident stroke and stroke mortality were prospectively examined in 86 142 women in the Nurses' Health Study, aged 34-59 years and free of diagnosed cardiovascular disease at baseline...
October 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28606218/dietary-supplement-use-in-the-older-population-of-iceland-and-association-with-mortality
#3
Birta Ólafsdóttir, Ingibjörg Gunnarsdóttir, Hjálmfríður Nikulásdóttir, Guðný Eiríksdóttir, Tamara B Harris, Lenore J Launer, Vilmundur Guðnason, Thórhallur I Halldórsson, Kristjana Einarsdóttir
Dietary supplements are often used by the elderly to improve their nutritional status. However, intake above the recommended dietary levels may be detrimental, and uncertainty exists on the potential health benefits of supplementation in this population. The aim of this study was to describe supplement use among Icelandic older adults and to assess its association with total mortality and CVD-related mortality. This study used data from the Age Gene/Environment Susceptibility-Reykjavik study, which recruited 5764 participants aged 66-98 years in 2002-2006...
May 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28518221/micronutrient-supplementation-in-adults-with-hiv-infection
#4
REVIEW
Marianne E Visser, Solange Durao, David Sinclair, James H Irlam, Nandi Siegfried
BACKGROUND: Micronutrient deficiencies are common among adults living with HIV disease, particularly in low-income settings where the diet may be low in essential vitamins and minerals. Some micronutrients play critical roles in maintenance of the immune system, and routine supplementation could therefore be beneficial. This is an update of a Cochrane Review previously published in 2010. OBJECTIVES: To assess whether micronutrient supplements are effective and safe in reducing mortality and HIV-related morbidity of HIV-positive adults (excluding pregnant women)...
May 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28384735/effect-of-baseline-nutritional-status-on-long-term-multivitamin-use-and-cardiovascular-disease-risk-a-secondary-analysis-of-the-physicians-health-study-ii-randomized-clinical-trial
#5
Susanne Rautiainen, J Michael Gaziano, William G Christen, Vadim Bubes, Gregory Kotler, Robert J Glynn, JoAnn E Manson, Julie E Buring, Howard D Sesso
Importance: Long-term multivitamin use had no effect on risk of cardiovascular disease (CVD) in the Physicians' Health Study II. Baseline nutritional status may have modified the lack of effect. Objective: To investigate effect modification by various baseline dietary factors on CVD risk in the Physicians' Health Study II. Design, Setting, and Participants: The Physicians' Health Study II was a randomized, double-blind, placebo-controlled trial testing multivitamin use (multivitamin [Centrum Silver] or placebo daily) among US male physicians...
June 1, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28377269/multivitamin-use-and-adverse-birth-outcomes-in-high-income-countries-a-systematic-review-and-meta-analysis
#6
REVIEW
Hanne T Wolf, Hanne K Hegaard, Lene D Huusom, Anja B Pinborg
BACKGROUND: In high-income countries, a healthy diet is widely accessible. However, a change toward a poor-quality diet with a low nutritional value in high-income countries has led to an inadequate vitamin intake during pregnancy. OBJECTIVE: We conducted a systematic review and meta-analysis to evaluate the association between multivitamin use among women in high-income countries and the risk of adverse birth outcomes (preterm birth [primary outcome], low birthweight, small for gestational age, stillbirth, neonatal death, perinatal mortality, and congenital anomalies without further specification)...
October 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28336109/multivitamin-mineral-supplements-rationale-and-safety
#7
REVIEW
Hans K Biesalski, Jana Tinz
Multivitamin/mineral supplements (MVMs) are widely used in many populations. MVMs, together with iron and folic acid, are recommended for pregnant women to improve birth outcome and to reduce low-birthweight and rates of miscarriage. However, MVM use is common in the general population as well. The aim of the present review was to evaluate the safety of long-term use of these supplements. To examine the safety of MVM use, we performed a literature search for randomized controlled studies involving supplementation with a combination of at least nine vitamins and three minerals at a maximum concentration of 100% of the Recommended Dietary Allowance...
April 2017: Nutrition
https://www.readbyqxmd.com/read/27812597/medication-and-nutritional-supplement-use-before-and-after-bariatric-surgery
#8
Charline Fernanda Backes, Edyane Lopes, Airton Tetelbom, Isabela Heineck
CONTEXT AND OBJECTIVE: Bariatric surgery has been an effective alternative treatment for morbid obesity and has resulted in decreased mortality, better control over comorbidities and reduced use of drugs. The objective of this study was to analyze the impact of bariatric surgery on medication drug and nutritional supplement use. DESIGN AND SETTING: Longitudinal study of before-and-after type, on 69 morbidly obese patients in a public hospital in Porto Alegre. METHODS: Through interviews, the presence of comorbidities and use of drugs with and without prescription were evaluated...
October 31, 2016: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/27718306/common-congenital-anomalies-environmental-causes-and-prevention-with-folic-acid-containing-multivitamins
#9
REVIEW
Swapnalee Sarmah, Pooja Muralidharan, James A Marrs
Congenital anomalies, congenital defects, or birth defects are significant causes of death in infants. The most common congenital defects are congenital heart defects (CHDs) and neural tube defects (NTDs). Defects induced by genetic mutations, environmental exposure to toxins, or a combination of these effects can result in congenital malformations, leading to infant death or long-term disabilities. These defects produce significant mortality and morbidity in the affected individuals, and families are affected emotional and financially...
September 2016: Birth Defects Research. Part C, Embryo Today: Reviews
https://www.readbyqxmd.com/read/27632426/coenzyme-q10-plus-multivitamin-treatment-prevents-cisplatin-ototoxicity-in-rats
#10
Laura Astolfi, Edi Simoni, Filippo Valente, Sara Ghiselli, Stavros Hatzopoulos, Milvia Chicca, Alessandro Martini
Cisplatin (Cpt) is known to induce a high level of oxidative stress, resulting in an increase of reactive oxygen species damaging the inner ear and causing hearing loss at high frequencies. Studies on animal models show that antioxidants may lower Cpt-induced ototoxicity. The aim of this study is to evaluate the ototoxic effects of two different protocols of Cpt administration in a Sprague-Dawley rat model, and to test in the same model the synergic protective effects of a solution of coenzyme Q10 terclatrate and Acuval 400®, a multivitamin supplement containing antioxidant agents and minerals (Acu-Qter)...
2016: PloS One
https://www.readbyqxmd.com/read/27625518/profile-and-risk-factors-for-congenital-heart-defects-a-study-in-a-tertiary-care-hospital
#11
Shaad Abqari, Akash Gupta, Tabassum Shahab, M U Rabbani, S Manazir Ali, Uzma Firdaus
INTRODUCTION: Congenital heart defects (CHDs) are an important cause of mortality and morbidity in children representing a major global health burden. It is thus important to determine their prevalence and spectrum and identify risk factors associated with the development of heart defects. MATERIALS AND METHODS: A case-control study was carried out in the Department of Pediatrics and Center of Cardiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India, from February 2014 to August 2015...
September 2016: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/27553772/multivitamin-mineral-supplements-rationale-and-safety-a-systematic-review
#12
REVIEW
Hans K Biesalski, Jana Tinz
Multivitamin/mineral supplements (MVM) are widely used in many populations. In particular, in pregnant women, MVM together with iron and folic acid are recommended to improve birth outcome and reduce low birth weight and rates of miscarriage. However, MVM use is common in the general population. This raises questions regarding the safety of long-term use of these supplements. To estimate the safety of MVM use, we performed a literature search for randomized, controlled studies for supplements with a combination of at least nine vitamins and three minerals at a maximum concentration of 100% of the recommended dietary allowance...
January 2017: Nutrition
https://www.readbyqxmd.com/read/27529612/plasma-n-6-fatty-acid-levels-are-associated-with-cd4-cell-counts-hospitalization-and-mortality-in-hiv-infected-patients
#13
RANDOMIZED CONTROLLED TRIAL
Edmond K Kabagambe, Amara E Ezeamama, David Guwatudde, Hannia Campos, Wafaie Fawzi
BACKGROUND: Fatty acids, including n-6 series, modulate immune function, but their effect on CD4 cell counts, death, or hospitalization in HIV-infected patients on antiretroviral therapy is unknown. METHODS: In a randomized trial for effects of multivitamins in HIV-infected patients in Uganda, we used gas chromatography to measure plasma n-6 fatty acids at baseline; determined CD4 counts at baseline, 3, 6, 12, and 18 months; and recorded hospitalization or death events...
December 15, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27507178/use-of-multivitamin-acidifier-and-azolla-in-the-diet-of-broiler-chickens
#14
M A Islam, M Nishibori
OBJECTIVE: The experiments were carried out to measure the effect of multivitamin, acidifier and Azolla on growth performance, profitability and lipid profiles of blood of broiler chickens to produce safe and cost effective broilers. METHODS: In experiment 1, 240 day-old Cobb-500 broiler chicks were fed diets; D1 (control), D2 (D1 with 1 mL multivitamin/liter water), D3 (D1 with 1 mL acidifier/liter water), D4 (D1 with 1 mL multivitamin and 2 mL acidifier/liter water) having 3 replications in each, and 20 chicks/replication...
May 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/27492013/common-medications-and-prostate-cancer-mortality-a-review
#15
Konrad H Stopsack, Alexandra J Greenberg, Lorelei A Mucci
PURPOSE: Most prostate cancer patients also have comorbidities that are treated with both prescription and nonprescription medications; furthermore, many use dietary supplements. We assess their association with prognosis after prostate cancer diagnosis, and we discuss methodological challenges and clinical implications. METHODS: We reviewed high-quality observational studies investigating the association of commonly used medications and supplements with prostate cancer-specific mortality...
June 2017: World Journal of Urology
https://www.readbyqxmd.com/read/27347720/etiology-of-diarrhea-nutritional-outcomes-and-novel-intestinal-biomarkers-in-tanzanian-infants
#16
Kerri B Gosselin, Said Aboud, Christine M McDonald, Sabrina Moyo, Nasim Khavari, Karim Manji, Rodrick Kisenge, Wafaie Fawzi, Mark Kellogg, Hao Q Tran, Gibson Kibiki, Jean Gratz, Jie Liu, Andrew Gewirtz, Eric Houpt, Christopher Duggan
OBJECTIVE: Diarrheal diseases are a leading cause of morbidity and mortality worldwide, but the etiology of diarrhea and its relation to nutritional outcomes in resource-limited settings is poorly defined. We sought to determine the etiology of community-acquired diarrhea in Tanzanian infants and to assess the association with anthropometrics and novel intestinal biomarkers. METHODS: A convenience sample of infants in a trial of zinc and/or multivitamin supplementation in Tanzania was selected...
January 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27190390/pro-should-we-correct-vitamin-d-deficiency-insufficiency-in-chronic-kidney-disease-patients-with-inactive-forms-of-vitamin-d-or-just-treat-them-with-active-vitamin-d-forms
#17
David J A Goldsmith
Evidence for the usefulness of using vitamin D to treat 'renal bone disease' is now nearly six decades old. In regular clinical practice, however, it is more like three decades, at most, that we have routinely been using vitamin D to try to prevent, or reverse, the impact of hyperparathyroidism on the skeleton of patients with chronic kidney disease (CKD). The practice has been in the main to use high doses of synthetic vitamin D compounds, not naturally occurring ones. However, the pharmacological impacts of the different vitamin D species and of their different modes, and styles of administration cannot be assumed to be uniform across the spectrum...
May 2016: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/26817503/effect-of-zinc-and-multivitamin-supplementation-on-the-growth-of-tanzanian-children-aged-6-84-wk-a-randomized-placebo-controlled-double-blind-trial
#18
RANDOMIZED CONTROLLED TRIAL
Lindsey M Locks, Karim P Manji, Christine M McDonald, Roland Kupka, Rodrick Kisenge, Said Aboud, Molin Wang, Wafaie W Fawzi, Christopher P Duggan
BACKGROUND: Poor child growth increases risks of mortality and morbidity. Micronutrient supplements have the potential to improve child growth. OBJECTIVE: We assessed the effect of daily zinc, multivitamin (vitamins C, E, and B-complex), and zinc and multivitamin (Zn+MV) supplementation on growth in infants in Tanzania. DESIGN: In this randomized, 2 × 2 factorial, double-blind trial, 2400 infants were randomly assigned to receive zinc, multivitamins, Zn+MVs, or a placebo at 6 wk of age and were followed up for 18 mo with monthly growth measurements...
March 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/26731864/-influence-of-dietary-supplementation-on-newborn-weight
#19
Kornelia Tomaszewska, Andrzej Klejewska, Ewelina Kostecka
The usage of multivitamin supplements for expectant mothers ought to always consult with a physician responsible for an expectant mother. Dietary supplements ought to be good chose to individual needs so that it can in an optimal way aid the health of an expectant mother and the progress of baby. The specialist literature and my ones researches show that a supplementary diet with multivitamin supplements and preparations with a folic acid in pregnancy can affect the mass of a neonate and increaser it. One should considers the implementation of multivitamin supplements by women from a risk group of the disorder development of an embryo...
2015: Przegla̧d Lekarski
https://www.readbyqxmd.com/read/26649185/complementary-therapy-and-survival-in-glioblastoma
#20
Bhageeradh H Mulpur, L Burt Nabors, Reid C Thompson, Jeffrey J Olson, Renato V LaRocca, Zachary Thompson, Kathleen M Egan
BACKGROUND: Complementary therapy (CAM) is common in cancer patients. We undertook this study to assess the association of complementary therapy usage with mortality in glioblastoma (GBM) patients. METHODS: The analysis was based on 470 patients. Information on current use of CAM was collected in structured interviews conducted a median of 6 weeks following GBM diagnosis. Proportional hazards regression was used to estimate hazard ratios (HRs) for GBM-related death according to the use of individual supplements with multivariate adjustment for known prognostic factors including age, KPS, and extent of tumor resection (ESR)...
September 2015: Neuro-oncology Practice
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