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Digital mammography

Imad Zyout, Roberto Togneri, Imad Zyout, Roberto Togneri, Roberto Togneri, Imad Zyout
Aiming at improving the performance of computer-aided detection of architectural distortion (AD) in mammograms, this paper investigates whether textural patterns of AD surrounding tissue (ST) have the potential to detect AD signatures. More specifically, for characterizing the presence of AD; we investigated the application of textural analysis for discriminating between AD surrounding tissue and normal breast parenchyma. We evaluated the underlying hypothesis using a dataset of 2544 regions of interest (ROI) obtained from the Digital Database for Screening Mammography (DDSM)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Mireille P Aujero, Sara C Gavenonis, Ron Benjamin, Zugui Zhang, Jacqueline S Holt
Purpose To compare the clinical performance of synthesized two-dimensional (s2D) mammography combined with digital breast tomosynthesis (DBT) with that of full-field digital mammography (FFDM) alone and FFDM combined with DBT in a large community-based screening population by analyzing recall rate, positive predictive value, and cancer detection rate. Materials and Methods This was a retrospective study approved by the institutional review board and was HIPAA compliant with waiver of informed consent. A total of 78 810 screening mammograms from October 11, 2011, to June 30, 2016, were retrospectively collected...
February 21, 2017: Radiology
Maria Castillo-García, Margarita Chevalier, Julia Garayoa, Alejandro Rodriguez-Ruiz, Diego García-Pinto, Julio Valverde
RATIONALE AND OBJECTIVES: The study aimed to compare the breast density estimates from two algorithms on full-field digital mammography (FFDM) and digital breast tomosynthesis (DBT) and to analyze the clinical implications. MATERIALS AND METHODS: We selected 561 FFDM and DBT examinations from patients without breast pathologies. Two versions of a commercial software (Quantra 2D and Quantra 3D) calculated the volumetric breast density automatically in FFDM and DBT, respectively...
February 14, 2017: Academic Radiology
Anton S Becker, Magda Marcon, Soleen Ghafoor, Moritz C Wurnig, Thomas Frauenfelder, Andreas Boss
OBJECTIVES: The aim of this study was to evaluate the diagnostic accuracy of a multipurpose image analysis software based on deep learning with artificial neural networks for the detection of breast cancer in an independent, dual-center mammography data set. MATERIALS AND METHODS: In this retrospective, Health Insurance Portability and Accountability Act-compliant study, all patients undergoing mammography in 2012 at our institution were reviewed (n = 3228). All of their prior and follow-up mammographies from a time span of 7 years (2008-2015) were considered as a reference for clinical diagnosis...
February 16, 2017: Investigative Radiology
Wei Tang, Fei-Xiang Hu, Hui Zhu, Qi-Feng Wang, Ya-Jia Gu, Wei-Jun Peng
PURPOSE: To compare the diagnostic efficiency of digital breast tomosynthesis (DBT) plus digital mammography (DM) and magnetic resonance imaging (MRI) plus DM in symptomatic women. MATERIALS AND METHODS: The protocol used in our study was accepted by the ethics committee at our hospital, and informed consent was obtained from all patients. Between June and December 2014, 197 patients with 238 histologically proven lesions all underwent DM, DBT and MRI. Two radiologists were responsible for interpreting all images according to the Breast Imaging Reporting and Data System (BI-RADS)...
February 17, 2017: Clinical Hemorheology and Microcirculation
Alan J Porter, Elizabeth B Evans, Lisa M Erzetich
INTRODUCTION: Modern full-field digital mammography (FFDM) appears to have increased the detection of breast microcalcification. This retrospective study aimed to assess whether this is associated with over-investigation and possible over-diagnosis of breast pathology of lesser significance. METHODS: Three 2-year periods were studied, in which different mammographic technologies were used exclusively viz., classical screen-film mammography (SFM) in 2003-04, computed radiography (CR) in 2009-10 and FFDM in 2012-13...
February 9, 2017: Journal of Medical Imaging and Radiation Oncology
Sara A Hunter, Colleen Morris, Karl Nelson, Brandon J Snyder, Thomas B Poulton
OBJECTIVE: The purpose of this study was to determine whether digital breast tomosynthesis (DBT) is a cost-effective alternative to full-field digital mammography (FFDM) for both Medicare and privately insured patients undergoing screening mammography. MATERIALS AND METHODS: A retrospective data analysis was performed between July 15, 2013, and July 14, 2014, with data on women presenting for screening mammography that included any additional radiologic workup (n = 6319)...
February 8, 2017: AJR. American Journal of Roentgenology
Francis P Boscoe, Xiuling Zhang
BACKGROUND: Digital mammography saw rapid adoption during the first decade of the 2000s. We were interested in identifying the times and locations where the technology was introduced within the state of New York as a way of illustrating the uneven introduction of this technology. METHODS: Using a sample of Medicare claims data from the period 2004-2012 from women aged 65 and over without cancer, we calculated the percentage of mammograms which were digital by zip code of residence and illustrated these with a series of smoothed maps...
February 2, 2017: Cancer Epidemiology, Biomarkers & Prevention
Ji Eun Baek, Bong Joo Kang, Sung Hun Kim, Hyun Sil Lee
BACKGROUND: Relative to Western women, Korean women show several differences in breast-related characteristics, including higher rates of dense breasts and small breasts. We investigated how mammographic composition and breast size affect the glandular dose during full-field digital mammography (FFDM) in Korean women using a radiation dose management system. METHODS: From June 1 to June 30, 2015, 2120 FFDM images from 560 patients were acquired and mammographic breast composition and breast size were assessed...
February 2, 2017: World Journal of Surgical Oncology
Moayyad E Suleiman, Patrick C Brennan, Mark F McEntee
Our objective was to analyze the agreement between organ dose estimated by different digital mammography units and calculated dose for clinical data. Digital Imaging and Communication in Medicine header information was extracted from 52,405 anonymized mammograms. Data were filtered to include images with no breast implants, breast thicknesses 20 to 110 mm, and complete exposure and quality assurance data. Mean glandular dose was calculated using methods by Dance et al., Wu et al., and Boone et al. Bland-Altman analysis and regression were used to study the agreement and correlation between organ and calculated doses...
January 2017: Journal of Medical Imaging
Natalie J Engmann, Christopher Scott, Matthew R Jensen, Lin Ma, Kathleen R Brandt, Amir Mahmoudzadeh, Serghei Malkov, Dana H Whaley, Carrie Hruska, Fang-Fang Wu, Stacey Winham, Diana L Miglioretti, Aaron D Norman, John Heine, John Shepherd, Vernon S Pankratz, Celine M Vachon, Karla Kerlikowske
BACKGROUND: Reductions in breast density with tamoxifen and aromatase inhibitors may be an intermediate marker of treatment response. We compare changes in volumetric breast density among breast cancer cases using tamoxifen or aromatase inhibitors (AI) to untreated women without breast cancer. METHODS: Breast cancer cases with a digital mammogram prior to diagnosis and after initiation of tamoxifen (n=366) or AI (n=403), and a sample of controls (n=2170) were identified from the Mayo Clinic Mammography Practice and San Francisco Mammography Registry...
February 1, 2017: Cancer Epidemiology, Biomarkers & Prevention
Suneeta Mall, Patrick Brennan, Claudia Mello-Thoms
RATIONALE AND OBJECTIVES: Visual search is an inhomogeneous yet efficient sampling process accomplished by the saccades and the central (foveal) vision. Areas that attract the central vision have been studied for errors in interpretation of medical imaging. In this study, we extend existing visual search studies to understand what characterizes areas that receive direct visual attention and elicit a mark by the radiologist (True and False Positive decisions) from those that elicit a mark but were captured by the peripheral vision...
January 27, 2017: Academic Radiology
Jeffrey D Miller, Machaon M Bonafede, Sally D Herschorn, Scott K Pohlman, Kathleen A Troeger, Laurie L Fajardo
PURPOSE: Better understanding regarding the clinical-economic value of digital breast tomosynthesis (DBT) for breast cancer screening for Medicaid enrollees is needed to help inform sound, value-based decision making. The objective of this study was to conduct a clinical-economic value analysis of DBT for breast cancer screening among women enrolled in Medicaid to assess the potential clinical benefits, associated expenditures, and net budget impact of DBT. METHODS: Two annual screening mammography scenarios were evaluated with an economic model: (1) full-field digital mammography and (2) combined full-field digital mammography and DBT...
January 26, 2017: Journal of the American College of Radiology: JACR
Wang Kei Ma, Rita Borgen, Judith Kelly, Sara Millington, Bev Hilton, Rob Aspin, Carla Lança, Peter Hogg
OBJECTIVES: Blurred images in Full Field Digital Mammography (FFDM) are a problem in the UK Breast Screening Programme. Technical recalls may be due to blurring not being seen on lower resolution monitors used for review. This study assesses the visual detection of blurring on a 2.3 megapixel (MP) monitor and a 5 MP report grade monitor and proposes an observer standard for the visual detection of blurring on a 5 MP reporting grade monitor. METHOD: Twenty-eight observers assessed 120 images for blurring; 20 had no blurring present whilst 100 had blurring imposed through mathematical simulation at 0...
January 30, 2017: British Journal of Radiology
Ana Pereira, Maria Luisa Garmendia, Ricardo Uauy, Paulina Neira, Sandra Lopez-Arana, Serghei Malkov, John Shepherd
PURPOSE: High mammographic breast density (BD) is a strong risk factor of breast cancer; however, little is known in women under 40 years of age. Recently, dual-energy X-ray Absorptiometry (DXA) has been developed as a low-dose method to measure BD in young populations. Thus, our aims were to describe BD in relation to risk factors in Chilean women under 40 years old and to explore the equivalence of DXA to mammography for the measurement of BD. METHODS: We selected 192 premenopausal Chilean female participants of the DERCAM study for whom we have anthropometric, sociodemographic, and gyneco-obstetric data...
January 28, 2017: Breast Cancer Research and Treatment
G Gennaro, A Ballaminut, G Contento
OBJECTIVES: This study aims to illustrate a multiparametric automatic method for monitoring long-term reproducibility of digital mammography systems, and its application on a large scale. METHODS: Twenty-five digital mammography systems employed within a regional screening programme were controlled weekly using the same type of phantom, whose images were analysed by an automatic software tool. To assess system reproducibility levels, 15 image quality indices (IQIs) were extracted and compared with the corresponding indices previously determined by a baseline procedure...
January 27, 2017: European Radiology
Susanne Wienbeck, Carsten Nowak, Antonia Zapf, Georg Stamm, Christina Unterberg-Buchwald, Joachim Lotz, Uwe Fischer
RATIONALE AND OBJECTIVES: The purpose of this ex vivo study was to investigate artifacts in a cone-beam breast computed tomography (CBBCT) caused by breast tissue markers. MATERIALS AND METHODS: Breast phantoms with self-made tissue pork mincemeat were created. Twenty-nine different, commercially available markers with varying marker size, composition, and shape were evaluated. A dedicated CBBCT evaluation of all phantoms was performed with 49 kVp, 50 and 100 mA, and marker orientation parallel and orthogonal to the scan direction...
January 24, 2017: Academic Radiology
Gezheng Wen, Mia K Markey, Subok Park
As psychophysical studies are resource-intensive to conduct, model observers are commonly used to assess and optimize medical imaging quality. Model observers are typically designed to detect at most one signal. However, in clinical practice, there may be multiple abnormalities in a single image set (e.g. multifocal multicentric (MFMC) breast cancer), which can impact treatment planning. Prevalence of signals can be different across anatomical regions, and human observers do not know the number or location of signals a priori...
February 21, 2017: Physics in Medicine and Biology
Chirag C Sthalekar, Yun Miao, Valencia Joyner Koomson
An interface circuit with signal processing and digitizing circuits for a high frequency, large area avalanche photodiode (APD) has been integrated in a 130 nm BiCMOS chip. The system enables the absolute oximetry of tissue using frequency domain Near Infrared Spectroscopy (fdNIRS). The system measures the light absorbed and scattered by the tissue by measuring the reduction in the amplitude of signal and phase shift introduced between the light source and detector which are placed a finite distance away from each other...
September 22, 2016: IEEE Transactions on Biomedical Circuits and Systems
Judy R James, William Pavlicek, James A Hanson, Thomas F Boltz, Bhavika K Patel
OBJECTIVE: We aimed to compare radiation dose received during contrast-enhanced spectral mammography (CESM) using high- and low-energy projections with radiation dose received during 2D full field digital mammography (FFDM) and 3D tomosynthesis on phantoms and patients with varying breast thickness and density. MATERIALS AND METHODS: A single left craniocaudal projection was chosen to determine the doses for 6214 patients who underwent 2D FFDM, 3662 patients who underwent 3D tomosynthesis, and 173 patients who underwent CESM in this retrospective study...
February 2017: AJR. American Journal of Roentgenology
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