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Digital mammography

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https://www.readbyqxmd.com/read/29342291/portuguese-study-of-mean-glandular-dose-in-mammography-and-comparison-with-european-references
#1
Cláudia Sá Dos Reis, Mário João Fartaria, João H Garcia Alves, Ana Pascoal
To characterise the mean glandular dose (MGD) in a sample of healthcare providers for digital mammography in Portugal. To compare the achieved values with European references. The MGD was measured on a poly-methyl-methacrylate phantom (45 mm) for each system using dosimeters. In addition, MGD was estimated using exposure settings collected from mammography exams in clinical context. Data were collected from 25 computed-radiography systems (CR) and 13 integrated digital (DR). For both measurements (phantom and clinical exposures), the average MGD for CR was higher compared to the DR...
January 12, 2018: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/29328943/interval-breast-cancers-in-the-screening-with-tomosynthesis-or-standard-mammography-storm-population-based-trial
#2
Nehmat Houssami, Daniela Bernardi, Francesca Caumo, Silvia Brunelli, Carmine Fantò, Marvi Valentini, Giovanna Romanucci, Maria A Gentilini, Manuel Zorzi, Petra Macaskill
BACKGROUND & METHODS: The prospective 'screening with tomosynthesis or standard mammography' (STORM) trial recruited women participating in biennial breast screening in Italy (2011-2012), and compared sequential screen-readings based on 2D-mammography alone or based on tomosynthesis (integrated 2D/3D-mammography). The STORM trial showed that tomosynthesis screen-reading significantly increased breast cancer detection compared to 2D-mammography alone. The present study completes reporting of the trial by examining interval breast cancers ascertained at two year follow-up...
January 9, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29319344/clinical-performance-metrics-of-3d-stereoscopic-digital-mammography-compared-with-2d-digital-mammography-observer-study
#3
Akiko Daidoji, Takatoshi Aoki, Seiichi Murakami, Mari Miyata, Masami Fujii, Takefumi Katsuki, Yuzuru Inoue, Yuko Tashima, Yoshika Nagata, Keiji Hirata, Fumihiro Tanaka, Yukunori Korogi
OBJECTIVE: To assess the clinical performance of three-dimensional stereoscopic digital mammography (3DsDM) compared with two-dimensional digital mammography (2DDM) for breast lesion diagnosis with jackknife free-response receiver operating characteristics (JAFROC) observer study. METHODS: Forty pairs of standard-dose 2DDM and their 3DsDM images were used for an observer performance study. A total of 18 lesions were identified as the reference standard of actionable breast lesions (BI-RADS category 3 or more) by 2 breast radiologists...
January 10, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29318276/association-of-screening-and-treatment-with-breast-cancer-mortality-by-molecular-subtype-in-us-women-2000-2012
#4
Sylvia K Plevritis, Diego Munoz, Allison W Kurian, Natasha K Stout, Oguzhan Alagoz, Aimee M Near, Sandra J Lee, Jeroen J van den Broek, Xuelin Huang, Clyde B Schechter, Brian L Sprague, Juhee Song, Harry J de Koning, Amy Trentham-Dietz, Nicolien T van Ravesteyn, Ronald Gangnon, Young Chandler, Yisheng Li, Cong Xu, Mehmet Ali Ergun, Hui Huang, Donald A Berry, Jeanne S Mandelblatt
Importance: Given recent advances in screening mammography and adjuvant therapy (treatment), quantifying their separate and combined effects on US breast cancer mortality reductions by molecular subtype could guide future decisions to reduce disease burden. Objective: To evaluate the contributions associated with screening and treatment to breast cancer mortality reductions by molecular subtype based on estrogen-receptor (ER) and human epidermal growth factor receptor 2 (ERBB2, formerly HER2 or HER2/neu)...
January 9, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29317041/contrast-enhanced-spectral-mammography-a-review
#5
Bhavika K Patel, M B I Lobbes, John Lewin
Contrast-enhanced spectral mammography (CESM) provides low-energy 2D mammographic images comparable to standard digital mammography and a post-contrast recombined image to assess tumor neovascularity similar to magnetic resonance imaging (MRI). The utilization of CESM in the United States is currently low but could increase rapidly given many potential indications for clinical use. This article discusses historical background and literature review of indications and diagnostic accuracy of CESM to date. CESM is a growing technique for breast cancer detection and diagnosis that has levels of sensitivity and specificity on par with contrast-enhanced breast MRI...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29317035/deciphering-the-breast-density-inform-law-movement-implications-for-practice
#6
Sean D Raj, Valerie Fein-Zachary, Priscilla J Slanetz
Although dense breast tissue is a normal and routine finding on screening mammography, dense breast tissue is associated with an independent increased risk for breast cancer. It is well known that screening mammography has a decreased sensitivity for cancer detection in women with dense breasts. Over the past decade, there has been increased interest generated among patients, physicians, and legislators regarding how best to screen dense-breasted women culminating in 2009 with the passage of a breast density notification law in Connecticut...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29317033/emerging-breast-imaging-technologies-on-the-horizon
#7
Srinivasan Vedantham, Andrew Karellas
Early detection of breast cancers by mammography in conjunction with adjuvant therapy has contributed to reduction in breast cancer mortality. Mammography remains the "gold-standard" for breast cancer screening but is limited by tissue superposition. Digital breast tomosynthesis and more recently, dedicated breast computed tomography have been developed to alleviate the tissue superposition problem. However, all of these modalities rely upon x-ray attenuation contrast to provide anatomical images, and there are ongoing efforts to develop and clinically translate alternative modalities...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29311416/average-glandular-dose-in-paired-digital-mammography-and-digital-breast-tomosynthesis-acquisitions-in-a-population-based-screening-program-effects-of-measuring-breast-density-air-kerma-and-beam-quality
#8
Bjørn Helge Østerås, Per Skaane, Randi Gullien, Anne Catrine Tregde Martinsen
The main purpose was to compare average glandular dose (AGD) for same-compression digital mammography (DM) and digital breast tomosynthesis (DBT) acquisitions in a population based screening program, with and without breast density stratification, as determined by automatically calculated breast density (QuantraTM). Secondary, to compare AGD estimates based on measured breast density, air kerma and half value layer (HVL) to DICOM metadata based estimates. AGD was estimated for 3819 women participating in the screening trial...
January 9, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29273225/breast-density-why-all-the-fuss
#9
REVIEW
S J Vinnicombe
The term "breast density" or mammographic density (MD) denotes those components of breast parenchyma visualised at mammography that are denser than adipose tissue. MD is composed of a mixture of epithelial and stromal components, notably collagen, in variable proportions. MD is most commonly assessed in clinical practice with the time-honoured method of visual estimation of area-based percent density (PMD) on a mammogram, with categorisation into quartiles. The computerised semi-automated thresholding method, Cumulus, also yielding area-based percent density, is widely used for research purposes; however, the advent of fully automated volumetric methods developed as a consequence of the widespread use of digital mammography (DM) and yielding both absolute and percent dense volumes, has resulted in an explosion of interest in MD recently...
December 19, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29273223/personalised-screening-is-this-the-way-forward
#10
REVIEW
F J Gilbert, A Selamoglu
Screening with mammography has been implemented in many countries across the world with most offering 2-yearly examinations between the ages of 50-69 years. Robust modelling tools that include breast density and single nucleotide polymorphisms (SNPs) have been developed to predict which women are most likely to develop breast cancer. Mammographic sensitivity is poor in women with the densest category of breast tissue, and even women with heterogeneously dense tissue may benefit from additional supplemental imaging...
December 19, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29260730/measurement-of-effective-detective-quantum-efficiency-for-a-photon-counting-scanning-mammography-system-and-comparison-with-two-flat-panel-full-field-digital-mammography-systems
#11
Tim J Wood, Craig S Moore, John R Saunderson, Andy W Beavis
Effective Detective Quantum Efficiency (eDQE) describes the resolution and noise properties of an imaging system along with scatter and primary transmission, all measured under clinically appropriate conditions. Effective dose efficiency (eDE) is the eDQE normalised to mean glandular dose and has been proposed as a useful metric for the optimisation of clinical imaging systems. The aim of this study was to develop a methodology for measuring eDQE and eDE on a Philips MicroDose Mammography (MDM) L30 photon counting scanning system, and to compare performance with two conventional flat panel systems...
December 20, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29249352/quantitative-breast-density-analysis-using-tomosynthesis-and-comparison-with-mri-and-digital-mammography
#12
Woo Kyung Moon, Jie-Fan Chang, Chung-Ming Lo, Jung Min Chang, Su Hyun Lee, Sung Ui Shin, Chiun-Sheng Huang, Ruey-Feng Chang
BACKGROUND AND OBJECTIVE: Breast density at mammography has been used as markers of breast cancer risk. However, newly introduced tomosynthesis and computer-aided quantitative method could provide more reliable breast density evaluation. METHODS: In the experiment, 98 tomosynthesis image volumes were obtained from 98 women. For each case, an automatic skin removal was used and followed by a fuzzy c-mean (FCM) classifier which separated the fibroglandular tissues from other tissues in breast area...
February 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29247886/microcalcification-morphological-descriptors-and-parenchyma-fractal-dimension-hierarchically-interact-in-breast-cancer-a-diagnostic-perspective
#13
Garima Verma, Maria Laura Luciani, Alessandro Palombo, Linda Metaxa, Giovanna Panzironi, Federica Pediconi, Alessandro Giuliani, Mariano Bizzarri, Virginia Todde
INTRODUCTION: Herein, we propose a Systems Biology approach aimed at identifying quantitative morphological parameters useful in discriminating benign from malignant breast microcalcifications at digital mammography. MATERIALS AND METHODS: The study includes 31 patients in which microcalcifications had been detected during XR mammography and were further confirmed by stereotactic (XR-guided) biopsies. Patients were classified according to the BIRADS (Breast Imaging-Reporting and Data System), along with their parenchyma fractal dimension and biopsy size...
December 11, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29239711/interval-breast-cancer-rates-and-histopathologic-tumor-characteristics-after-false-positive-findings-at-mammography-in-a-population-based-screening-program
#14
Solveig Hofvind, Silje Sagstad, Sofie Sebuødegård, Ying Chen, Marta Roman, Christoph I Lee
Purpose To compare rates and tumor characteristics of interval breast cancers (IBCs) detected after a negative versus false-positive screening among women participating in the Norwegian Breast Cancer Screening Program. Materials and Methods The Cancer Registry Regulation approved this retrospective study. Information about 423 445 women aged 49-71 years who underwent 789 481 full-field digital mammographic screening examinations during 2004-2012 was extracted from the Cancer Registry of Norway. Rates and odds ratios of IBC among women with a negative (the reference group) versus a false-positive screening were estimated by using logistic regression models adjusted for age at diagnosis and county of residence...
December 14, 2017: Radiology
https://www.readbyqxmd.com/read/29237146/digital-breast-tomosynthesis-with-synthesized-two-dimensional-images-versus-full-field-digital-mammography-for-population-screening-outcomes-from-the-verona-screening-program
#15
Francesca Caumo, Manuel Zorzi, Silvia Brunelli, Giovanna Romanucci, Rossella Rella, Loredana Cugola, Paola Bricolo, Chiara Fedato, Stefania Montemezzi, Nehmat Houssami
Purpose To examine the outcomes of a breast cancer screening program based on digital breast tomosynthesis (DBT) plus synthesized two-dimensional (2D) mammography compared with those after full-field digital mammography (FFDM). Materials and Methods This prospective study included 16 666 asymptomatic women aged 50-69 years who were recruited in April 2015 through March 2016 for DBT plus synthetic 2D screening in the Verona screening program. A comparison cohort of women screened with FFDM (n = 14 423) in the previous year was included...
December 13, 2017: Radiology
https://www.readbyqxmd.com/read/29230524/one-view-digital-breast-tomosynthesis-as-a-stand-alone-modality-for-breast-cancer-detection-do-we-need-more
#16
Alejandro Rodriguez-Ruiz, Albert Gubern-Merida, Mechli Imhof-Tas, Susanne Lardenoije, Alexander J T Wanders, Ingvar Andersson, Sophia Zackrisson, Kristina Lång, Magnus Dustler, Nico Karssemeijer, Ritse M Mann, Ioannis Sechopoulos
PURPOSE: To compare the performance of one-view digital breast tomosynthesis (1v-DBT) to that of three other protocols combining DBT and mammography (DM) for breast cancer detection. MATERIALS AND METHODS: Six radiologists, three experienced with 1v-DBT in screening, retrospectively reviewed 181 cases (76 malignant, 50 benign, 55 normal) in two sessions. First, they scored sequentially: 1v-DBT (medio-lateral oblique, MLO), 1v-DBT (MLO) + 1v-DM (cranio-caudal, CC) and two-view DM + DBT (2v-DM+2v-DBT)...
December 11, 2017: European Radiology
https://www.readbyqxmd.com/read/29208760/effectiveness-of-and-overdiagnosis-from-mammography-screening-in-the-netherlands-population-based-study
#17
Philippe Autier, Magali Boniol, Alice Koechlin, Cécile Pizot, Mathieu Boniol
Objective To analyse stage specific incidence of breast cancer in the Netherlands where women have been invited to biennial mammography screening since 1989 (ages 50-69) and 1997 (ages 70-75), and to assess changes in breast cancer mortality and quantified overdiagnosis.Design Population based study.Setting Mammography screening programme, the Netherlands.Participants Dutch women of all ages, 1989 to 2012.Main outcome measures Stage specific age adjusted incidence of breast cancer from 1989 to 2012. The extra numbers of in situ and stage 1 breast tumours associated with screening were estimated by comparing rates in women aged 50-74 with those in age groups not invited to screening...
December 5, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29202159/mammographic-phantoms-frequently-used-to-determine-image-quality-a-comparative-study
#18
Khaled AlKhalifah, Ajit Brindabhan
Appropriate diagnosis depends on the image quality of the mammographic system. Phantoms are normally used, since they have physical properties similar to those of different human tissues, and are important tools for quality assurance of mammography equipment, evaluation of image quality, and accurate determination of patient dosage. The aim of this study was to evaluate various mammographic phantoms used to determine the image quality of digital mammographic equipment. METHODS: Three phantoms were used: an American College of Radiology accreditation phantom, an MTM 100/R, and a tissue-equivalent phantom...
2017: Journal of Allied Health
https://www.readbyqxmd.com/read/29200686/an-investigation-of-bayes-algorithm-and-neural-networks-for-identifying-the-breast-cancer
#19
E Udayakumar, S Santhi, P Vetrivelan
Context: Breast cancer is a biggest threat to women. X-ray mammography is the most effective method for early detection and screening of breast cancer. It is a tough challenge for the radiologist in reading mammography since it does not provide consistent result every time. Aim: To improve the primary sign of this disease, computer-aided diagnosis schemes have been developed. Using monitor, digital images of mammography are displayed and they can be lightened or darkened before they are printed on the film...
July 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29199085/diagnostic-performance-of-mammographic-texture-analysis-in-the-differential-diagnosis-of-benign-and-malignant-breast-tumors
#20
Zhiming Li, Lan Yu, Xin Wang, Haiyang Yu, Yuanxiang Gao, Yande Ren, Gang Wang, Xiaoming Zhou
BACKGROUND: The purpose of this study was to investigate the diagnostic performance of mammographic texture analysis in the differential diagnosis of benign and malignant breast tumors. PATIENTS AND METHODS: Digital mammography images were obtained from the Picture Archiving and Communication System at our institute. Texture features of mammographic images were calculated. Mann-Whitney U test was used to identify differences between the benign and malignant group...
November 9, 2017: Clinical Breast Cancer
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