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Digital mammography

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https://www.readbyqxmd.com/read/28716454/a-randomised-trial-of-screening-with-digital-breast-tomosynthesis-plus-conventional-digital-2d-mammography-versus-2d-mammography-alone-in-younger-higher-risk-women
#1
Anthony J Maxwell, Michael Michell, Yit Y Lim, Susan M Astley, Mary Wilson, Emma Hurley, D Gareth Evans, Anthony Howell, Asif Iqbal, John Kotre, Stephen Duffy, Julie Morris
INTRODUCTION: Digital breast tomosynthesis (DBT) has been shown to increase invasive cancer detection rates at screening compared to full field digital (2D) mammography alone, and some studies have reported a reduction in the screening recall rate. No prospective randomised studies of DBT have previously been published. This study compares recall rates with 2D mammography with and without concurrent DBT in women in their forties with a family history of breast cancer undergoing incident screening...
June 30, 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28715278/bi-rads-category-3-comparison-probably-benign-category-after-recall-from-screening-before-and-after-implementation-of-digital-breast-tomosynthesis
#2
Elizabeth S McDonald, Anne Marie McCarthy, Susan P Weinstein, Mitchell D Schnall, Emily F Conant
Purpose To evaluate Breast Imaging Reporting and Data System (BI-RADS) category 3 assessment at diagnostic examination after recall from screening in a large urban population after implementation of digital breast tomosynthesis (DBT) by focusing both on overall use and use stratified by recalled finding type and outcome at 2 years. Materials and Methods This was an intuitional review board-approved and HIPAA-compliant retrospective review of 10 728 digital mammography (DM) examinations from September 1, 2010, to August 30, 2011, and 15 571 screening DBT examinations from October 1, 2011, to February 28, 2013...
July 17, 2017: Radiology
https://www.readbyqxmd.com/read/28713173/a-standard-mammography-unit-standard-3d-ultrasound-probe-fusion-prototype-first-results
#3
Rüdiger Schulz-Wendtland, Sebastian M Jud, Peter A Fasching, Arndt Hartmann, Marcus Radicke, Claudia Rauh, Michael Uder, Marius Wunderle, Paul Gass, Hanna Langemann, Matthias W Beckmann, Julius Emons
AIM: The combination of different imaging modalities through the use of fusion devices promises significant diagnostic improvement for breast pathology. The aim of this study was to evaluate image quality and clinical feasibility of a prototype fusion device (fusion prototype) constructed from a standard tomosynthesis mammography unit and a standard 3D ultrasound probe using a new method of breast compression. MATERIALS AND METHODS: Imaging was performed on 5 mastectomy specimens from patients with confirmed DCIS or invasive carcinoma (BI-RADS (™) 6)...
June 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28712610/the-hiqa-s-health-technology-assessment-of-breast-screening-highlighting-some-of-the-challenges-posed-by-evaluations-of-screening-programs
#4
Conor Teljeur, Patrick Moran, Patricia Harrington, Máirín Ryan
A review of the Health Information and Quality Authority's (HIQA) assessment of breast cancer surveillance cancer criticized how the results were presented and interpreted. The health technology assessment (HTA) investigated surveillance options for women aged less than 50 years who were at elevated risk of breast cancer. Surveillance strategies using digital mammography, magnetic resonance imaging, or a combination of the two modalities were modeled on the basis of diagnostic test accuracy. The HTA faced a number of issues, including the use of diagnostic test accuracy as a surrogate for long-term outcomes; modeling interventions that were not considered acceptable to clinicians; and extrapolating for screening intervals and age ranges not directly supported by available evidence...
July 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28710582/comparison-of-digital-mammography-and-digital-breast-tomosynthesis-in-the-detection-of-architectural-distortion
#5
Elizabeth H Dibble, Ana P Lourenco, Grayson L Baird, Robert C Ward, A Stanley Maynard, Martha B Mainiero
OBJECTIVES: To compare interobserver variability (IOV), reader confidence, and sensitivity/specificity in detecting architectural distortion (AD) on digital mammography (DM) versus digital breast tomosynthesis (DBT). METHODS: This IRB-approved, HIPAA-compliant reader study used a counterbalanced experimental design. We searched radiology reports for AD on screening mammograms from 5 March 2012-27 November 2013. Cases were consensus-reviewed. Controls were selected from demographically matched non-AD examinations...
July 14, 2017: European Radiology
https://www.readbyqxmd.com/read/28707529/interpretation-of-digital-breast-tomosynthesis-preliminary-study-on-comparison-with-picture-archiving-and-communication-system-pacs-and-dedicated-workstation
#6
Young Seon Kim, Jung Min Chang, Ann Yi, Sung Ui Shin, Myung Eun Lee, Won Hwa Kim, Nariya Cho, Woo Kyung Moon
OBJECTIVES: To compare the diagnostic accuracy and efficiency in the interpretation of digital breast tomosynthesis (DBT) images using picture archiving and communication system (PACS) and a dedicated workstation. METHODS: A total of 97 DBT images performed for screening or diagnostic purposes were stored in both a workstation and PACS, and evaluated in combination with digital mammography by three independent radiologists retrospectively. Breast Imaging Reporting and Data System final assessments and likelihood of malignancy (%) were assigned and the interpretation time when using the workstation and PACS was recorded...
July 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28696192/breast-cancer-screening-does-tomosynthesis-augment-mammography
#7
REVIEW
Traci A Takahashi, Christoph I Lee, Kay M Johnson
Digital breast tomosynthesis (DBT) is a relatively new imaging technology that is being adopted widely for breast cancer screening. Initial evidence suggests that it may reduce recall rates and increase cancer detection rates when added to digital mammography screening. However, more rigorous, prospective studies are needed to determine whether it improves long-term clinical outcomes of breast cancer screening.
July 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28681390/a-deep-feature-fusion-methodology-for-breast-cancer-diagnosis-demonstrated-on-three-imaging-modality-datasets
#8
Natalia Antropova, Benjamin Q Huynh, Maryellen L Giger
Deep learning methods for radiomics/computer-aided diagnosis (CADx) are often prohibited by small datasets, long computation time, and the need for extensive image preprocessing. We present a methodology that extracts and pools low- to mid-level features using a pre-trained convolutional neural network and fuses them with handcrafted radiomic features computed using conventional CADx methods. Our fusion-based method demonstrates significant improvements to previous breast cancer CADx methods across three clinical imaging modalities (dynamic contrast-enhanced MRI, full-field digital mammography, and ultrasound) in terms of predictive performance in the task of estimating lesion malignancy...
July 6, 2017: Medical Physics
https://www.readbyqxmd.com/read/28668424/digital-breast-tomosynthesis-versus-full-field-digital-mammography-which-modality-provides-more-accurate-prediction-of-margin-status-in-specimen-radiography
#9
Heba A Amer, Florian Schmitzberger, Barbara Ingold-Heppner, Julia Kussmaul, Manal F El Tohamy, Hazim I Tantawy, B Hamm, M Makowski, Eva M Fallenberg
OBJECTIVES: To evaluate the reliability of tumor margin assessment in specimen radiography (SR) using digital breast tomosynthesis (DBT) and full-field digital mammography (FFDM) in comparison to postoperative histopathology margin status as the gold standard. METHODS: After ethics committee approval, 102 consecutive patients who underwent breast conservative surgery for nonpalpable proven breast cancer were prospectively included. All patients underwent ultrasound/mammography-guided wire localization of their lesions...
August 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28666723/the-reproducibility-of-changes-in-diagnostic-figures-of-merit-across-laboratory-and-clinical-imaging-reader-studies
#10
Frank W Samuelson, Craig K Abbey
RATIONALE AND OBJECTIVES: In this paper we examine which comparisons of reading performance between diagnostic imaging systems made in controlled retrospective laboratory studies may be representative of what we observe in later clinical studies. The change in a meaningful diagnostic figure of merit between two diagnostic modalities should be qualitatively or quantitatively comparable across all kinds of studies. MATERIALS AND METHODS: In this meta-study we examine the reproducibility of relative measures of sensitivity, false positive fraction (FPF), area under the receiver operating characteristic (ROC) curve, and expected utility across laboratory and observational clinical studies for several different breast imaging modalities, including screen film mammography, digital mammography, breast tomosynthesis, and ultrasound...
June 27, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28649652/the-epidemiology-radiology-and-biological-characteristics-of-interval-breast-cancers-in-population-mammography-screening
#11
Nehmat Houssami, Kylie Hunter
An interval breast cancer is a cancer that emerges following a negative mammographic screen. This overview describes the epidemiology, and the radiological and biological characteristics of interval breast cancers in population mammography screening. Notwithstanding possible differences in ascertainment of interval breast cancers, there was broad variability in reported interval breast cancer rates (range 7.0 to 49.3 per 10,000 screens) reflecting heterogeneity in underlying breast cancer rates, screening rounds (initial or repeat screens), and the length and phase of the inter-screening interval...
2017: NPJ Breast Cancer
https://www.readbyqxmd.com/read/28647388/characterization-of-breast-masses-in-digital-breast-tomosynthesis-and-digital-mammograms-an-observer-performance-study
#12
Heang-Ping Chan, Mark A Helvie, Lubomir Hadjiiski, Deborah O Jeffries, Katherine A Klein, Colleen H Neal, Mitra Noroozian, Chintana Paramagul, Marilyn A Roubidoux
RATIONALE AND OBJECTIVES: This study aimed to compare Breast Imaging Reporting and Data System (BI-RADS) assessment of lesions in two-view digital mammogram (DM) to two-view wide-angle digital breast tomosynthesis (DBT) without DM. MATERIALS AND METHODS: With Institutional Review Board approval and written informed consent, two-view DBTs were acquired from 134 subjects and the corresponding DMs were collected retrospectively. The study included 125 subjects with 61 malignant (size: 3...
June 21, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28639832/comparing-diagnostic-performance-of-digital-breast-tomosynthesis-and-full-field-digital-mammography-in-a-hybrid-screening-environment
#13
Catherine S Giess, Sarvenaz Pourjabbar, Ivan K Ip, Ronilda Lacson, Emily Alper, Ramin Khorasani
OBJECTIVE: The purpose of this study is to compare the diagnostic performance of screening digital breast tomosynthesis (DBT) to that of full-field digital mammography (FFDM) in a mixed DBT and FFDM imaging environment. MATERIALS AND METHODS: This retrospective observational study consisted of all female patients undergoing screening DBT or FFDM at an academic medical center and outpatient imaging facility between October 2012 and May 2015. Patient demographics and personal history of breast cancer were collected from the electronic medical record...
June 22, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28624977/interaction-of-mammographic-breast-density-with-menopausal-status-and-postmenopausal-hormone-use-in-relation-to-the-risk-of-aggressive-breast-cancer-subtypes
#14
Lusine Yaghjyan, Rulla M Tamimi, Kimberly A Bertrand, Christopher G Scott, Matthew R Jensen, V Shane Pankratz, Kathy Brandt, Daniel Visscher, Aaron Norman, Fergus Couch, John Shepherd, Bo Fan, Yunn-Yi Chen, Lin Ma, Andrew H Beck, Steven R Cummings, Karla Kerlikowske, Celine M Vachon
PURPOSE: We examined the associations of mammographic breast density with breast cancer risk by tumor aggressiveness and by menopausal status and current postmenopausal hormone therapy. METHODS: This study included 2596 invasive breast cancer cases and 4059 controls selected from participants of four nested case-control studies within four established cohorts: the Mayo Mammography Health Study, the Nurses' Health Study, Nurses' Health Study II, and San Francisco Mammography Registry...
June 17, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28614990/screening-organization-and-recall-rate-in-a-regional-breast-screening-programme
#15
Tina Beruchashwili, Rema Gvamichava, Stephen W Duffy
Objective To use results on recall rates from a regional non-population-based breast screening programme to inform practice in a planned national population-based programme. Methods We analysed data on rates of recall for further assessment in 27,327 mammographic screening episodes in 2015-2016 in the breast screening programme in the city of Tbilisi, Georgia. Screening was done by two-view digital mammography with double reading in women aged 40-70, and further assessment took place at the same clinic and during the same visit as the initial screening mammogram...
January 1, 2017: Journal of Medical Screening
https://www.readbyqxmd.com/read/28609204/surveillance-of-women-with-the-brca1-or-brca2-mutation-by-using-biannual-automated-breast-us-mr-imaging-and-mammography
#16
Jan C M van Zelst, Roel D M Mus, Gwendolyn Woldringh, Matthieu J C M Rutten, Peter Bult, Suzan Vreemann, Mathijn de Jong, Nico Karssemeijer, Nicoline Hoogerbrugge, Ritse M Mann
Purpose To evaluate a multimodal surveillance regimen including yearly full-field digital (FFD) mammography, dynamic contrast agent-enhanced (DCE) magnetic resonance (MR) imaging, and biannual automated breast (AB) ultrasonography (US) in women with BRCA1 and BRCA2 mutations. Materials and Methods This prospective multicenter trial enrolled 296 carriers of the BRCA mutation (153 BRCA1 and 128 BRCA2 carriers, and 15 women with first-degree untested relatives) between September 2010 and November 2012, with follow-up until November 2015...
June 13, 2017: Radiology
https://www.readbyqxmd.com/read/28603939/mesh-free-based-variational-level-set-evolution-for-breast-region-segmentation-and-abnormality-detection-using-mammograms
#17
Kanchan L Kashyap, Manish K Bajpai, Pritee Khanna, George Giakos
Automatic segmentation of abnormal region is a crucial task in computer aided detection system using mammograms. In this work an automatic abnormality detection algorithm using mammographic images is proposed. In the preprocessing step, partial differential equation based variational level set method is employed for breast region extraction. The evolution of the level set method is done by applying mesh-free based radial basis function. The limitation of mesh-based approach is removed by using mesh-free based RBF method...
June 11, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/28583146/the-effect-of-volumetric-breast-density-on-the-risk-of-screen-detected-and-interval-breast-cancers-a-cohort-study
#18
Johanna O P Wanders, Katharina Holland, Nico Karssemeijer, Petra H M Peeters, Wouter B Veldhuis, Ritse M Mann, Carla H van Gils
BACKGROUND: In the light of the breast density legislation in the USA, it is important to know a woman's breast cancer risk, but particularly her risk of a tumor that is not detected through mammographic screening (interval cancer). Therefore, we examined the associations of automatically measured volumetric breast density with screen-detected and interval cancer risk, separately. METHODS: Volumetric breast measures were assessed automatically using Volpara version 1...
June 5, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28561776/qualitative-versus-quantitative-mammographic-breast-density-assessment-applications-for-the-us-and-abroad
#19
REVIEW
Stamatia Destounis, Andrea Arieno, Renee Morgan, Christina Roberts, Ariane Chan
Mammographic breast density (MBD) has been proven to be an important risk factor for breast cancer and an important determinant of mammographic screening performance. The measurement of density has changed dramatically since its inception. Initial qualitative measurement methods have been found to have limited consistency between readers, and in regards to breast cancer risk. Following the introduction of full-field digital mammography, more sophisticated measurement methodology is now possible. Automated computer-based density measurements can provide consistent, reproducible, and objective results...
May 31, 2017: Diagnostics
https://www.readbyqxmd.com/read/28558329/risk-stratification-of-women-with-false-positive-test-results-in-mammography-screening-based-on-mammographic-morphology-and-density-a-case-control-study
#20
Rikke Rass Winkel, My von Euler-Chelpin, Elsebeth Lynge, Pengfei Diao, Martin Lillholm, Michiel Kallenberg, Julie Lyng Forman, Michael Bachmann Nielsen, Wei Yao Uldall, Mads Nielsen, Ilse Vejborg
The long-term risk of breast cancer is increased in women with false-positive (FP) mammography screening results. We investigated whether mammographic morphology and/or density can be used to stratify these women according to their risk of future breast cancer METHODS: We undertook a case-control study nested in the population-based screening programme in Copenhagen, Denmark. We included 288 cases and 288 controls based on a cohort of 4743 women with at least one FP-test result in 1991-2005 who were followed up until 17 April 2008...
May 27, 2017: Cancer Epidemiology
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