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https://www.readbyqxmd.com/read/27889224/fetal-megacystis-a-systematic-review
#1
REVIEW
K Taghavi, C Sharpe, M D Stringer
: Fetal megacystis is variably defined and understood. The literature on fetal megacystis was systematically reviewed, focusing on prenatal diagnosis, associations and outcomes. This yielded a total of 18 primary references and eight secondary references. Fetal megacystis has an estimated first-trimester prevalence of between 1:330 and 1:1670, with a male to female ratio of 8:1. In the first trimester, megacystis is most commonly defined as a longitudinal bladder dimension of ≥7 mm...
October 8, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27888609/effects-of-lorcaserin-on-pre-existing-valvulopathy-a-pooled-analysis-of-phase-3-trials
#2
Neil J Weissman, Steven R Smith, Randi Fain, Nancy Hall, William R Shanahan
OBJECTIVE: To evaluate the effects of lorcaserin in patients with pre-existing Food and Drug Administration (FDA)-defined valvulopathy. METHODS: This is a pooled, post hoc analysis of three Phase 3 studies. BLOOM and BLOSSOM patients were 18 to 65 years of age without diabetes and with a body mass index (BMI) of 27 to 29.9 kg/m(2) and ≥1 weight-related comorbidity or a BMI of 30 to 45 kg/m(2) . BLOOM-DM patients had a BMI of 27 to 45 kg/m(2) and type 2 diabetes...
November 26, 2016: Obesity
https://www.readbyqxmd.com/read/27885047/morphological-variability-of-the-arterial-valve-in-common-arterial-trunk-and-the-concept-of-normality
#3
Gabriel Romero Liguori, Marcelo Biscegli Jatene, Siew Yen Ho, Vera Demarchi Aiello
OBJECTIVE: Until now, no study established a morphometric evaluation of the truncal valve dysplasia and a description of its different presentation patterns. Thus, authors conducted an anatomopathological study describing the gross features and histological findings of the truncal valve. METHODS: 50 common arterial trunk (CAT) specimens were examined. The number of valvar leaflets was determined and valvar dysplasia was classified as absent, mild, moderate or severe...
November 24, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27879282/sex-related-discordance-between-aortic-valve-calcification-and-hemodynamic-severity-of-aortic-stenosis-is-valvular-fibrosis-the-explanation
#4
Louis Simard, Nancy Côté, François Dagenais, Patrick Mathieu, Christian Couture, Sylvain Trahan, Yohan Bossé, Siamak Mohammadi, Sylvain Pagé, Philippe Joubert, Marie-Annick Clavel
RATIONALE: Calcific aortic stenosis (AS) is characterized by calcium deposition in valve leaflets. However, women present lower aortic valve calcification (AVC) loads than men for the same AS hemodynamic severity. OBJECTIVE: We thus aimed to assess sex-differences in aortic valve fibro-calcific remodelling. METHODS AND RESULTS: One hundred and twenty-five patients underwent Doppler-echocardiography and multidetector-computed-tomography within 3 months prior to aortic valve replacement...
November 22, 2016: Circulation Research
https://www.readbyqxmd.com/read/27873174/prognostic-value-of-exercise-left-ventricular-end-systolic-volume-index-in-patients-with-asymptomatic-aortic-regurgitation-an-exercise-echocardiography-study
#5
Yukio Sato, Masaki Izumo, Kengo Suzuki, Seisyou Kou, Kihei Yoneyama, Maya Tsukahara, Kanako Teramoto, Keisuke Minami, Shingo Kuwata, Ryo Kamijima, Kei Mizukoshi, Akio Hayashi, Sachihiko Nobuoka, Eiji Ohtaki, Tomoo Harada, Yoshihiro J Akashi
BACKGROUND: Surgical timing of chronic aortic regurgitation (AR) remains a matter of debate because of limited data. This study assessed the prognostic value of exercise echocardiography in asymptomatic AR. METHODS: This prospective study included 60 consecutive asymptomatic patients with isolated moderate or severe AR (mean regurgitant volume 56.7 ± 11.8 ml) and preserved ejection fraction who underwent exercise echocardiography. The clinical outcomes were defined by the presence of major adverse cardiovascular events (MACE) and the indication for aortic valve replacement (AVR) with class I or IIa classification in the current guidelines...
November 21, 2016: Journal of Echocardiography
https://www.readbyqxmd.com/read/27869890/-anmco-sic-sici-gise-sicch-consensus-document-risk-stratification-in-elderly-patients-undergoing-cardiac-surgery-and-transcatheter-aortic-valve-implantation
#6
Giovanni Pulignano, Michele Massimo Gulizia, Samuele Baldasseroni, Francesco Bedogni, Giovanni Cioffi, Ciro Indolfi, Francesco Romeo, Adriano Murrone, Francesco Musumeci, Alessandro Parolari, Leonardo Patanè, Paolo Giuseppe Pino, Annalisa Mongiardo, Carmen Spaccarotella, Roberto Di Bartolomeo, Giuseppe Musumeci
Aortic stenosis is one the most frequent valvular diseases in developed countries, and its impact on public healthcare resources and assistance is increasing. A substantial proportion of elderly patients with severe aortic stenosis is frequently not eligible for surgery because of advanced age, frailty and multiple comorbidities. Transcatheter aortic valve implantation (TAVI) enables the treatment of very elderly patients at high or prohibitive surgical risk considered ineligible for surgery and with an acceptable life expectancy...
September 2016: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/27852483/mitraclip-therapy-for-mitral-regurgitation-primary-mitral-regurgitation
#7
REVIEW
G Athappan, Mohammad Qasim Raza, Samir R Kapadia
Primary mitral regurgitation (MR) owing to degenerative changes in the structural components of the mitral valve is a common acquired valvular pathology in the elderly. Surgical correction with mitral valve repair (MVRe) or replacement (MVR) is the mainstay of therapy. A significant proportion of patients are ineligible for MVRe/MVR owing to prohibitive surgical risk from advanced age, poor ventricular function, or associated comorbidities. Percutaneous mitral valve repair techniques have been developed to fill this void...
January 2016: Interventional cardiology clinics
https://www.readbyqxmd.com/read/27851760/new-plants-from-the-lower-devonian-pingyipu-group-jiangyou-county-sichuan-province-china
#8
Dianne Edwards, Bao-Yin Geng, Cheng-Sen Li
Descriptions of Lower Devonian plants from Yunnan, South China, have revolutionized concepts of diversity and disparity in tracheophytes soon after they became established on land. Sichuan assemblages have received little attention since their discovery almost 25 years ago and require revision. With this objective, fieldwork involving detailed logging and collection of fossils was undertaken in the Longmenshan Mountain Region, Jiangyou County and yielded the two new taxa described here. They are preserved as coalified compressions and impressions that allowed morphological but not anatomical analyses...
2016: PloS One
https://www.readbyqxmd.com/read/27836257/analysis-and-compensation-for-the-cascade-dead-zones-in-the-proportional-control-valve
#9
Bing Xu, Qi Su, Junhui Zhang, Zhenyu Lu
The four-way proportional directional control valve has been widely used as the main stage spring constant for the two-stage proportional control valve (PDV). Since a tradeoff should be made between manufacturing costs and static performance, two symmetry dead-zones are introduced in the main stage spring constant: the center dead-zone caused by the center floating position and the intermediate dead-zone caused by the intermediate position. Though the intermediate dead-zone is much smaller than the center dead-zone, it has significant effect on the dynamic position tracking performance...
November 8, 2016: ISA Transactions
https://www.readbyqxmd.com/read/27820610/national-registry-data-and-record-linkage-to-inform-postmarket-surveillance-of-prosthetic-aortic-valve-models-over-15-years
#10
Graeme L Hickey, Ben Bridgewater, Stuart W Grant, John Deanfield, John Parkinson, Alan J Bryan, Malcolm Dalrymple-Hay, Neil Moat, Iain Buchan, Joel Dunning
Importance: Postmarket evidence generation for medical devices is important yet limited for prosthetic aortic valve devices in the United Kingdom. Objective: To identify prosthetic aortic valve models that display unexpected patterns of mortality or reintervention using routinely collected national registry data and record linkage. Design, Setting, and Participants: This observational study used data from all National Health Service and private hospitals in England and Wales that submit data to the National Adult Cardiac Surgery Audit (NACSA)...
November 7, 2016: JAMA Internal Medicine
https://www.readbyqxmd.com/read/27817129/the-use-of-stepper-motor-controlled-proportional-valve-for-fio2-calculation-in-the-ventilator-and-its-control-with-fuzzy-logic
#11
Adem Gölcük, İnan Güler
This article proposes the employment of a proportional valve that can calculate the amount of oxygen in the air to be given to patient in accordance with the amount of FiO2 which is set from the control menu of the ventilation device. To actualize this, a stepper motor-controlled proportional valve was used. Two counts of valves were employed in order to control the gases with 2 bar pressure that came from both the oxygen and medical air tanks. Oxygen and medical air manometers alongside the pressure regulators were utilized to perform this task...
January 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/27816175/-transfemoral-tavi-procedure-in-women-minimally-invasive-technique
#12
H Benamer, B Chevalier, A Roy, M A Bouzid, C Perdrix, P Garot, T Hovasse, T Unterseeh, S Champagne, T Lefèvre
Demographic data point to a substantial proportion of women in the population of elderly patients with an increasing prevalence of aortic stenosis. Implantation of an aortic bioprosthesis via an endovascular approach known as Transcatheter aortic valve implantation (TAVI) in patients presenting with a symptomatic tight aortic stenosis (severe aortic stenosis) (AS) is an alternative therapeutic option to surgical aortic valve replacement in patients at high surgical risk or ineligible for surgery. The literature has shown that this technique seems to be particularly beneficial in female patients...
November 2, 2016: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/27803857/trabeculectomy-with-ex-press-implant-versus-ahmed-glaucoma-valve-implantation-a-comparative-study
#13
Michael Waisbourd, Naomi Fischer, Hadas Shalev, Oriel Spierer, Elad Ben Artsi, Rony Rachmiel, Gabi Shemesh, Shimon Kurtz
AIM: To compare the surgical outcomes of trabeculectomy with Ex-PRESS implant and Ahmed glaucoma valve (AGV) implantation. METHODS: Patients who underwent trabeculectomy with Ex-PRESS implants or AGV implantation separately were included in this retrospective chart review. Main outcome measures were surgical failure and complications. Failure was defined as intraocular pressure (IOP) >21 mm Hg or <5 mm Hg on two consecutive visits after 3mo, reoperation for glaucoma, or loss of light perception...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27803800/recent-advances-in-aortic-valve-replacement-for-aortic-stenosis
#14
REVIEW
Ahmed Al-Adhami, Nawwar Al-Attar
Aortic valve replacement is no longer an operation that is approached solely through a median sternotomy. Recent advances in the fields of transcatheter valves have expanded the proportion of patients eligible for intervention. Comparisons between transcatheter valves and conventional surgery have shown non-inferiority of transcatheter valve implants in patients with a high or intermediate pre-operative predictive risk. With advances in our understanding of sutureless valves and their applicability to minimally invasive surgery, the invasiveness and trauma of surgery can be reduced with potential improvements in outcome...
2016: F1000Research
https://www.readbyqxmd.com/read/27803362/toward-optimal-decision-making-among-vulnerable-patients-referred-for-cardiac-surgery-a-qualitative-analysis-of-patient-and-provider-perspectives
#15
Ryan A Gainer, Janet Curran, Karen J Buth, Jennie G David, Jean-Francois Légaré, Gregory M Hirsch
OBJECTIVES: Comprehension of risks, benefits, and alternative treatment options has been shown to be poor among patients referred for cardiac interventions. Patients' values and preferences are rarely explicitly sought. An increasing proportion of frail and older patients are undergoing complex cardiac surgical procedures with increased risk of both mortality and prolonged institutional care. We sought input from patients and caregivers to determine the optimal approach to decision making in this vulnerable patient population...
November 1, 2016: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/27798318/comparing-usual-care-with-a-warfarin-initiation-protocol-after-mechanical-heart-valve-replacement
#16
Gregory Roberts, Rasha Razooqi, Stephen Quinn
BACKGROUND: The immediate postoperative warfarin sensitivity for patients receiving heart valve prostheses is increased. Established warfarin initiation protocols may lack clinical applicability, resulting in dosing based on clinical judgment. OBJECTIVE: To compare current practice for warfarin initiation with a known warfarin initiation protocol, with doses proportionally reduced to account for the increased postoperative sensitivity. METHODS: We compared the Mechanical Heart Valve Warfarin Initiation Protocol (Protocol group) with current practice (clinical judgment-Empirical group) for patients receiving mechanical heart valves in an observational before-and-after format...
October 25, 2016: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/27797979/prognosis-assessment-of-persistent-left-bundle-branch-block-after-tavi-by-an-electrophysiological-and-remote-monitoring-risk-adapted-algorithm-rationale-and-design-of-the-multicentre-lbbb-tavi-study
#17
Grégoire Massoullié, Pierre Bordachar, Didier Irles, Christophe Caussin, Antoine Da Costa, Pascal Defaye, Frédéric Jean, Alexis Mechulan, Pierre Mondoly, Géraud Souteyrand, Bruno Pereira, Sylvain Ploux, Romain Eschalier
INTRODUCTION: Percutaneous aortic valve replacement (transcatheter aortic valve implantation (TAVI)) notably increases the likelihood of the appearance of a complete left bundle branch block (LBBB) by direct lesion of the LBB of His. This block can lead to high-grade atrioventricular conduction disturbances responsible for a poorer prognosis. The management of this complication remains controversial. METHOD AND ANALYSIS: The screening of LBBB after TAVI persisting for more than 24 hours will be conducted by surface ECG...
October 26, 2016: BMJ Open
https://www.readbyqxmd.com/read/27770001/aortic-cross-sectional-area-height-ratio-and-outcomes-in-patients-with-a-trileaflet-aortic-valve-and-a-dilated-aorta
#18
Ahmad Masri, Vidyasagar Kalahasti, Lars G Svensson, Eric E Roselli, Douglas Johnston, Donald Hammer, Paul Schoenhagen, Brian P Griffin, Milind Y Desai
BACKGROUND: -In patients with a dilated proximal ascending aorta and trileaflet aortic valve (TAV), we sought to assess a) factors independently associated with increased long-term mortality and b) the incremental prognostic utility of indexing aortic root to patient height. METHODS: -We studied consecutive patients with a dilated aortic root (≥4 cm) that underwent echocardiography and gated contrast-enhanced thoracic aortic computed tomography or magnetic resonance angiography between 2003-2007...
October 21, 2016: Circulation
https://www.readbyqxmd.com/read/27766269/chronic-type-a-aortic-dissection-two-cases-and-a-review-of-current-management-strategies
#19
Conor F Hynes, Michael D Greenberg, Shawn Sarin, Gregory D Trachiotis
Stanford Type A aortic dissection is a rapidly progressing disease process that is often fatal without emergent surgical repair. A small proportion of Type A dissections go undiagnosed in the acute phase and are found upon delayed presentation of symptoms or incidentally. These chronic lesions may have a distinct natural history that may have a better prognosis and could potentially be managed differently then those presenting acutely. The method of repair depends on location and extent of the false lumen, as well as involvement of critical structures and branch arteries...
February 2016: Aorta (Stamford, Conn.)
https://www.readbyqxmd.com/read/27765308/transcatheter-aortic-valve-replacement-the-new-standard-in-patients-with-previous%C3%A2-coronary%C3%A2-bypass%C3%A2-grafting
#20
Jochen Reinöhl, Klaus Kaier, Holger Reinecke, Lutz Frankenstein, Andreas Zirlik, Manfred Zehender, Constantin von Zur Mühlen, Christoph Bode, Peter Stachon
OBJECTIVES: The aim of this study was to assess how the introduction of transcatheter aortic valve replacement (TAVR) has changed clinical practice and outcome in patients who have previously undergone coronary artery bypass grafting (CABG). BACKGROUND: A significant proportion of patients admitted for aortic valve replacement have previously undergone CABG and are therefore at increased operative risk in case of redo surgery. METHODS: In-hospital outcome data were analyzed from patients with or without previous CABG undergoing isolated surgical aortic valve replacement or TAVR in Germany from 2007 to 2013...
October 24, 2016: JACC. Cardiovascular Interventions
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