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https://www.readbyqxmd.com/read/27485723/is-prophylactic-laser-peripheral-iridotomy-for-primary-angle-closure-suspects-a-risk-factor-for-cataract-progression-the-chennai-eye-disease-incidence-study
#1
Lingam Vijaya, Rashima Asokan, Manish Panday, Ronnie George
BACKGROUND: To report the risk of cataract progression among primary angle closure suspects (PACS) 6 years after they underwent laser peripheral iridotomy (LPI). METHODS: In the Chennai Eye Disease Incidence Study, 6 years after their baseline evaluation, 4421 subjects were examined again. As part of a detailed evaluation cataract was graded using the Lens Opacities Classification System II; progression was defined as change of cataract by two or more grades or history of cataract surgery in the 6-year period...
August 2, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/26426422/a-novel-c-terminal-cib2-calcium-and-integrin-binding-protein-2-mutation-associated-with-non-syndromic-hearing-loss-in-a-hispanic-family
#2
Kunjan Patel, Arnaud P Giese, J M Grossheim, Rashmi S Hegde, Rashima S Hegde, Maria Delio, Joy Samanich, Saima Riazuddin, Gregory I Frolenkov, Jinlu Cai, Zubair M Ahmed, Bernice E Morrow
Hearing loss is a complex disorder caused by both genetic and environmental factors. Previously, mutations in CIB2 have been identified as a common cause of genetic hearing loss in Pakistani and Turkish populations. Here we report a novel (c.556C>T; p.(Arg186Trp)) transition mutation in the CIB2 gene identified through whole exome sequencing (WES) in a Caribbean Hispanic family with non-syndromic hearing loss. CIB2 belongs to the family of calcium-and integrin-binding (CIB) proteins. The carboxy-termini of CIB proteins are associated with calcium binding and intracellular signaling...
2015: PloS One
https://www.readbyqxmd.com/read/26290386/six-year-incidence-of-visually-significant-age-related-cataract-the-chennai-eye-disease-incidence-study
#3
Manish Panday, Ronnie George, Rashima Asokan, Satyamangalam Ve Ramesh, Lokapavani Velumuri, Nikhil S Choudhari, Sachi Devi Boddupalli, Govindan T Sunil, Lingam Vijaya
BACKGROUND: The aim of this study is to report the 6-year incidence of age-related cataract in a population-based study. DESIGN: The design used is a population-based cohort study. PARTICIPANTS: A cohort of 2484 phakic subjects, aged 40 years and above at baseline, from a south Indian population was included in the study. METHODS: Bilateral phakics with visual acuity of 6/12 or better and cataract less than N2, C2 and P2 on the Lens Opacities Classification System II at baseline were included...
March 2016: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/25950660/the-prevalence-of-pseudoexfoliation-and-the-long-term-changes-in-eyes-with-pseudoexfoliation-in-a-south-indian-population
#4
Lingam Vijaya, Rashima Asokan, Manish Panday, Nikhil S Choudhari, Ramesh V Sathyamangalam, Lokapavani Velumuri, Ronnie George
PURPOSE: To report the prevalence, long-term changes and associated factors for pseudoexfoliation (PEX) in a population aged 40 years and above from rural and urban south India. MATERIALS AND METHODS: At baseline (the Chennai Glaucoma Study), 7774 subjects were examined. After 6 years, as a part of the incidence study, 133 of the 290 subjects diagnosed with PEX at baseline were reexamined for long-term changes. Participants had detailed examination at base hospital...
June 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/25798827/genetic-association-of-snps-near-atoh7-card10-cdkn2b-cdc7-and-six1-six6-with-the-endophenotypes-of-primary-open-angle-glaucoma-in-indian-population
#5
Ferdinamarie Sharmila Philomenadin, Rashima Asokan, Viswanathan N, Ronnie George, Vijaya Lingam, Sripriya Sarangapani
Primary open angle glaucoma (POAG) belonging to a group of optic neuropathies, result from interaction between genetic and environmental factors. Study of associations with quantitative traits (QTs) is one of the successful strategies to understand the complex genetics of POAG. The current study attempts to explore the association of variations near/in genes like ATOH7, SIX1/SIX6 complex, CDKN2B, CARD10, and CDC7 with POAG and its QTs including vertical cup to disc ratio (VCDR), central corneal thickness (CCT), intra ocular pressure (IOP), and axial length (AL)...
2015: PloS One
https://www.readbyqxmd.com/read/25795479/six-year-incidence-and-baseline-risk-factors-for-pseudoexfoliation-in-a-south-indian-population-the-chennai-eye-disease-incidence-study
#6
Lingam Vijaya, Rashima Asokan, Manish Panday, Nikhil S Choudhari, Sathyamangalam Ve Ramesh, Lokapavani Velumuri, Ronnie George
OBJECTIVE: To estimate the 6-year incidence of pseudoexfoliation and its risk factors in a South Indian population. DESIGN: Longitudinal population-based study. PARTICIPANTS: Subjects 40 years of age or older without pseudoexfoliation at baseline. METHODS: Participants were examined at baseline and after a 6-year interval. The presence of pseudoexfoliation was looked for after pupillary dilation in either or both eyes at 1 or more locations...
June 2015: Ophthalmology
https://www.readbyqxmd.com/read/25388449/six-year-incidence-of-ocular-hypertension-in-a-south-indian-population-the-chennai-eye-disease-incidence-study
#7
Manish Panday, Ronnie George, Rashima Asokan, Satyamangalam Ve Ramesh, Lokapavani Velumuri, Nikhil S Choudhari, Sachi Devi Boddupalli, Govindan T Sunil, Lingam Vijaya
AIMS: To report the 6-year incidence and risk factors for ocular hypertension (OHT) in a population-based study in southern India. METHODS: 6 years after baseline evaluation, 56.9% subjects (participants:non-participants, 4421:3353) were re-examined at the base hospital. Incident OHT was defined as an intraocular pressure above the 97.5th centile for the population with no evidence of glaucoma in the 2852 phakic subjects, 40 years or older. Subjects with trauma, laser or incisional surgery at baseline or follow-up were excluded (total exclusions: 1569)...
May 2015: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/25103268/baseline-risk-factors-for-incidence-of-blindness-in-a-south-indian-population-the-chennai-eye-disease-incidence-study
#8
Lingam Vijaya, Rashima Asokan, Manish Panday, Nikhil S Choudhari, Sathyamangalam Ve Ramesh, Lokapavani Velumuri, Sachi Devi Boddupalli, Govindan T Sunil, Ronnie George
PURPOSE: To report the baseline risk factors and causes for incident blindness. METHODS: Six years after the baseline study, 4419 subjects from the cohort underwent a detailed examination at the base hospital. Incident blindness was defined by World Health Organization criteria as visual acuity of less than 6/120 (3/60) and/or a visual field of less than 10° in the better-seeing eye at the 6-year follow-up, provided that the eye had a visual acuity of better than or equal to 6/120 (3/60) and visual field greater than 10° at baseline...
September 2014: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/24650554/predictors-for-incidence-of-primary-open-angle-glaucoma-in-a-south-indian-population-the-chennai-eye-disease-incidence-study
#9
Lingam Vijaya, Asokan Rashima, Manish Panday, Nikhil S Choudhari, Sathyamangalam Ve Ramesh, Velumuri Lokapavani, Sachi Devi Boddupalli, Govindan T Sunil, Ronnie George
OBJECTIVE: To determine the 6-year incidence of primary open-angle glaucoma (POAG) and its associated predictors. DESIGN: Population-based cohort study. PARTICIPANTS: A total of 4316 subjects without POAG at baseline who were 40 years of age and older from a south Indian population. METHODS: Participants were examined at baseline and after a 6-year interval. Detailed ophthalmic examination included applanation tonometry, gonioscopy, pachymetry, optic disc evaluation, and automated perimetry...
July 2014: Ophthalmology
https://www.readbyqxmd.com/read/24492502/comparison-of-saccadic-reaction-time-between-normal-and-glaucoma-using-an-eye-movement-perimeter
#10
COMPARATIVE STUDY
Deepmala Mazumdar, J J M Pel, Manish Panday, Rashima Asokan, L Vijaya, B Shantha, Ronnie George, J Van Der Steen
AIM: To compare the saccadic reaction time (SRT) in both the central and peripheral visual field in normal and glaucomatous eyes using eye movement perimetery (EMP). MATERIALS AND METHODS: Fifty-four normal and 25 glaucoma subjects underwent EMP and visual field testing on the Humphrey Field Analyser (HFA) 24-2 program. The EMP is based on infrared tracking of the corneal reflex. Fifty-four test locations corresponding to the locations on the 24-2 HFA program were tested...
January 2014: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/24457361/prevalence-and-causes-of-vision-loss-in-central-and-south-asia-1990-2010
#11
REVIEW
Jost B Jonas, Ronnie George, Rashima Asokan, Seth R Flaxman, Jill Keeffe, Janet Leasher, Kovin Naidoo, Konrad Pesudovs, Holly Price, Lingam Vijaya, Richard A White, Tien Y Wong, Serge Resnikoff, Hugh R Taylor, Rupert R A Bourne
BACKGROUND: To examine the prevalence, patterns and trends of vision impairment and its causes from 1990 to 2010 in Central and South Asia. METHODS: Based on the Global Burden of Diseases Study 2010 and ongoing literature searches, we examined prevalence and causes of moderate and severe vision impairment (MSVI; presenting visual acuity <6/18, ≥3/60) and blindness (presenting visual acuity <3/60). RESULTS: In Central Asia, the estimated age-standardised prevalence of blindness decreased from 0...
May 2014: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/24145562/long-term-change-in-central-corneal-thickness-from-a-glaucoma-perspective
#12
Nikhil S Choudhari, Ronnie George, Ramesh Ve Sathyamangalam, Prema Raju, Rashima Asokan, Lokapavani Velumuri, Lingam Vijaya
AIM: To investigate the longitudinal change in central corneal thickness (CCT) over 3 years in patients with glaucoma. MATERIALS AND METHODS: The Chennai Glaucoma Follow-up Study, an offshoot of the Chennai Glaucoma Study, was designed to evaluate the progression of glaucoma. A cohort of participants in the Chennai Glaucoma Study that were suffering from glaucoma or were at a higher risk for glaucoma underwent comprehensive ophthalmic evaluation at the base hospital at 6-month intervals during the years 2004 to 2007...
October 2013: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/24075428/six-year-incidence-of-angle-closure-disease-in-a-south-indian-population-the-chennai-eye-disease-incidence-study
#13
Lingam Vijaya, Rashima Asokan, Manish Panday, Nikhil S Choudhari, Sathyamangalam Ve Ramesh, Lokapavani Velumuri, Sachi Devi Boddupalli, Govindan T Sunil, Ronnie George
PURPOSE: To estimate the 6-year incidence of primary angle-closure (PAC) disease among adult population aged 40 years and older from rural and urban south India. DESIGN: Population-based longitudinal study. METHODS: A complete ophthalmologic examination, including applanation tonometry, gonioscopy, biometry, stereoscopic fundus examination, and automated perimetry was performed at both baseline and at the 6-year follow up at base hospital...
December 2013: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/23619490/prevalence-and-causes-of-low-vision-and-blindness-in-an-urban-population-the-chennai-glaucoma-study
#14
Lingam Vijaya, Ronnie George, Rashima Asokan, Lokapavani Velumuri, Sathyamangalam Ve Ramesh
AIM: To evaluate the prevalence and causes of low vision and blindness in an urban south Indian population. SETTINGS AND DESIGN: Population-based cross-sectional study. Exactly 3850 subjects aged 40 years and above from Chennai city were examined at a dedicated facility in the base hospital. MATERIALS AND METHODS: All subjects had a complete ophthalmic examination that included best-corrected visual acuity. Low vision and blindness were defined using World Health Organization (WHO) criteria...
April 2014: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/22647262/structural-brain-atlases-design-rationale-and-applications-in-normal-and-pathological-cohorts
#15
REVIEW
Pravat K Mandal, Rashima Mahajan, Ivo D Dinov
Structural magnetic resonance imaging (MRI) provides anatomical information about the brain in healthy as well as in diseased conditions. On the other hand, functional MRI (fMRI) provides information on the brain activity during performance of a specific task. Analysis of fMRI data requires the registration of the data to a reference brain template in order to identify the activated brain regions. Brain templates also find application in other neuroimaging modalities, such as diffusion tensor imaging and multi-voxel spectroscopy...
2012: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/22112236/prevalence-and-associated-factors-for-pterygium-and-pinguecula-in-a-south-indian-population
#16
Rashima Asokan, Ramesh S Venkatasubbu, Lokapavani Velumuri, Vijaya Lingam, Ronnie George
PURPOSE: To describe the prevalence and factors associated with pterygium and pinguecula in a south Indian population. METHODS: The Chennai Glaucoma Study examined 7774 (Urban 3850, Rural 3924) subjects aged above 40 years. All subjects underwent a comprehensive ophthalmic evaluation. Personal history, occupation and lifetime ultraviolet exposure were documented. The presence of pterygium and pinguecula on slit-lamp examination was recorded. The prevalence of pterygium and pinguecula, differences in the rural and urban populations and their association with age, gender, residence, nature of occupation, lifetime ultraviolet radiation exposure, tobacco use (smoking/smokeless), alcohol use, diabetes mellitus and hypertension were analyzed...
January 2012: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/21150021/importance-of-population-based-studies-in-clinical-practice
#17
REVIEW
George Ronnie, Ramesh Sathyamangalam Ve, Lokapavani Velumuri, Rashima Asokan, Lingam Vijaya
In the last decade, there have been reports on the prevalence of glaucoma from the Vellore Eye Survey, Andhra Pradesh Eye Diseases Survey, Aravind Comprehensive Eye Survey, Chennai Glaucoma Study and West Bengal Glaucoma Study. Population-based studies provide important information regarding the prevalence and risk factors for glaucoma. They also highlight regional differences in the prevalence of various types of glaucoma. It is possible to gather important insights regarding the number of persons affected with glaucoma and the proportion with undiagnosed disease...
January 2011: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/20413926/outcomes-of-cataract-surgery-in-a-rural-and-urban-south-indian-population
#18
Lingam Vijaya, Ronnie George, A Rashima, Prema Raju, Hemamalini Arvind, Mani Baskaran, Ramesh S Ve
PURPOSE: To assess the visual outcome after cataract surgery in a south Indian population. MATERIALS AND METHODS: Population-based cross-sectional study of subjects aged 40 years or more. Three thousand nine hundred and twenty-four rural subjects from 27 contiguous villages and 3850 urban subjects from five randomly selected divisions were studied. All subjects underwent a comprehensive ophthalmic examination that included visual acuity, refraction, slit-lamp biomicroscopy, applanation tonometry, gonioscopy, and dilated retinal examination...
May 2010: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/20079536/central-corneal-thickness-in-adult-south-indians-the-chennai-glaucoma-study
#19
Lingam Vijaya, Ronnie George, Hemamalini Arvind, Satyamangalam Ve Ramesh, Mani Baskaran, Prema Raju, Rashima Asokan, Lokapavani Velumuri
OBJECTIVE: To evaluate the characteristics of central corneal thickness (CCT) and its association with age, gender, and intraocular pressure in rural and urban South Indian populations. DESIGN: Population-based cross-sectional study. PARTICIPANTS: Seven thousand seven hundred seventy-four subjects (rural-to-urban ratio, 3924:3850) aged 40 years and older were examined at a dedicated facility in the base hospital. INTERVENTION: All subjects underwent a complete ophthalmic examination that included CCT measurements with an ultrasonic pachymeter and applanation tonometry...
April 2010: Ophthalmology
https://www.readbyqxmd.com/read/18318332/promoting-breast-health-among-women-in-the-u-s-virgin-islands-a-focused-study-of-the-needs-of-caribbean-women
#20
Sandra Underwood, Edith Ramsay Johnson, Gloria Callwood, Edris E Evans, Alina Matthew, Casandra Scotland-Brooks, Chantal Hanley, Damali Johnson-Harrigan, Devette LeFlore, Dionne Williams, Harricia Samuels, Jahtara Francis, Jamela Arthur, Jowana Clinkscales, Martha Joseph, Nihjole Heskey, Rachel D'Abreau, Rashima Fleming, Stacey Penn, Tameka A Browne, Tiffany Donastorg, Yvette Scarbriel
Breast cancer is the number one cause of cancer death among women in the United States Virgin Islands. Consequently, the Bureau of Health has identified breast cancer as a priority health concern. Within the medical community, increasing emphasis is being placed on the importance of hereditary, familial, environmental, and behavioral risk factors to breast cancer control. Little research has been conducted regarding these factors, however, to explore their influence on breast cancer detection and breast cancer risk management...
December 2007: Journal of National Black Nurses' Association: JNBNA
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