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https://www.readbyqxmd.com/read/29783750/hysteresis-compensation-in-a-tactile-device-for-arterial-pulse-reproduction
#1
Fernando Carneiro, Paulo Abreu, Maria Teresa Restivo
This paper describes a system for training healthcare practitioners in the identification of different arterial pulses. The driving system uses a linear solenoid in an open loop force control. Due to the large hysteresis it exhibited, a form of compensation was implemented, based on the classic Preisach model of hysteresis. Implementation of said model resulted in a significant reduction of force tracking error, demonstrating the feasibility of the chosen approach for the intended application.
May 19, 2018: Sensors
https://www.readbyqxmd.com/read/29774336/raman-fingerprints-of-amyloid-structures
#2
Jessica D Flynn, Jennifer C Lee
Structural differences in pathological and functional amyloid fibrils have been investigated by Raman microspectroscopy. Second-derivative analyses of amide-I and amide-III bands distinguish parallel in-register β-sheets from a β-solenoid. Further, spatially resolved Raman spectra reveal molecular heterogeneity in amyloid structures.
May 18, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29758748/magnetic-field-generation-by-pointwise-zero-helicity-three-dimensional-steady-flow-of-an-incompressible-electrically-conducting-fluid
#3
Andrey Rasskazov, Roman Chertovskih, Vladislav Zheligovsky
We introduce six families of three-dimensional space-periodic steady solenoidal flows, whose kinetic helicity density is zero at any point. Four families are analytically defined. Flows in four families have zero helicity spectrum. Sample flows from five families are used to demonstrate numerically that neither zero kinetic helicity density nor zero helicity spectrum prohibit generation of large-scale magnetic field by the two most prominent dynamo mechanisms: the magnetic α-effect and negative eddy diffusivity...
April 2018: Physical Review. E
https://www.readbyqxmd.com/read/29746699/repeatsdb-lite-a-web-server-for-unit-annotation-of-tandem-repeat-proteins
#4
Layla Hirsh, Lisanna Paladin, Damiano Piovesan, Silvio C E Tosatto
RepeatsDB-lite (http://protein.bio.unipd.it/repeatsdb-lite) is a web server for the prediction of repetitive structural elements and units in tandem repeat (TR) proteins. TRs are a widespread but poorly annotated class of non-globular proteins carrying heterogeneous functions. RepeatsDB-lite extends the prediction to all TR types and strongly improves the performance both in terms of computational time and accuracy over previous methods, with precision above 95% for solenoid structures. The algorithm exploits an improved TR unit library derived from the RepeatsDB database to perform an iterative structural search and assignment...
May 9, 2018: Nucleic Acids Research
https://www.readbyqxmd.com/read/29735741/folding-cooperativity-and-allosteric-function-in-the-tandem-repeat-protein-class
#5
REVIEW
Albert Perez-Riba, Marie Synakewicz, Laura S Itzhaki
The term allostery was originally developed to describe structural changes in one binding site induced by the interaction of a partner molecule with a distant binding site, and it has been studied in depth in the field of enzymology. Here, we discuss the concept of action at a distance in relation to the folding and function of the solenoid class of tandem-repeat proteins such as tetratricopeptide repeats (TPRs) and ankyrin repeats. Distantly located repeats fold cooperatively, even though only nearest-neighbour interactions exist in these proteins...
June 19, 2018: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/29734684/comparing-the-folds-of-prions-and-other-pathogenic-amyloids
#6
REVIEW
José Miguel Flores-Fernández, Vineet Rathod, Holger Wille
Pathogenic amyloids are the main feature of several neurodegenerative disorders, such as Creutzfeldt⁻Jakob disease, Alzheimer’s disease, and Parkinson’s disease. High resolution structures of tau paired helical filaments (PHFs), amyloid-β(1-42) (Aβ(1-42)) fibrils, and α-synuclein fibrils were recently reported using cryo-electron microscopy. A high-resolution structure for the infectious prion protein, PrPSc , is not yet available due to its insolubility and its propensity to aggregate, but cryo-electron microscopy, X-ray fiber diffraction, and other approaches have defined the overall architecture of PrPSc as a 4-rung β-solenoid...
May 4, 2018: Pathogens
https://www.readbyqxmd.com/read/29729494/automated-detection-of-broad-nmr-spectra-19-f-nmr-of-paramagnetic-uf-4-and-195-pt-nmr-of-supported-pt-catalysts
#7
Christopher A Klug, Joel B Miller
The automated detection of broad NMR spectra via the controlled stepwise motion of the NMR probe along the field axis of the superconducting solenoid is demonstrated for the detection of 19 F NMR of paramagnetic UF4 and 195 Pt NMR of supported metal catalysts. The sensitivity advantages of performing these measurements at 2.3 T are discussed with reference to applying this methodology to room temperature in situ electrochemical 195 Pt NMR.
April 3, 2018: Solid State Nuclear Magnetic Resonance
https://www.readbyqxmd.com/read/29694781/composite-reinforcement-by-magnetic-control-of-fiber-density-and-orientation
#8
Omri Goldberg, Israel Greenfeld, H Daniel Wagner
The flexural rigidity of cylindrical specimens, composed of epoxy reinforced by short magnetized glass-fibers, was enhanced using weak magnetic fields (<100 mT). By spatially controlling the magnitude and direction of the field, and thereby the torques and forces acting locally on the fibers, the orientation and concentration of the fillers in the matrix could be tuned prior to curing. Unidirectional alignment of the fibers, achieved using an air-core solenoid, improved the fibers' contribution to the flexure modulus by a factor of three...
April 25, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29651716/super-secondary-structure-consisting-of-a-polyproline-ii-helix-and-a-%C3%AE-turn-in-leucine-rich-repeats-in-bacterial-type-iii-secretion-system-effectors
#9
Dashdavaa Batkhishig, Khurelbaatar Bilguun, Purevjav Enkhbayar, Hiroki Miyashita, Robert H Kretsinger, Norio Matsushima
Leucine rich repeats (LRRs) are present in over 100,000 proteins from viruses to eukaryotes. The LRRs are 20-30 residues long and occur in tandem. LRRs form parallel stacks of short β-strands and then assume a super helical arrangement called a solenoid structure. Individual LRRs are separated into highly conserved segment (HCS) with the consensus of LxxLxLxxNxL and variable segment (VS). Eight classes have been recognized. Bacterial LRRs are short and characterized by two prolines in the VS; the consensus is xxLPxLPxx with Nine residues (N-subtype) and xxLPxxLPxx with Ten residues (T-subtype)...
April 12, 2018: Protein Journal
https://www.readbyqxmd.com/read/29601593/a-sensitive-and-innovative-detection-method-for-rapid-c-reactive-proteins-analysis-based-on-a-micro-fluxgate-sensor-system
#10
Lei Guo, Zhen Yang, Shaotao Zhi, Zhu Feng, Chong Lei, Yong Zhou
A sensitive and innovative assay system based on a micro-MEMS-fluxgate sensor and immunomagnetic beads-labels was developed for the rapid analysis of C-reactive proteins (CRP). The fluxgate sensor presented in this study was fabricated through standard micro-electro-mechanical system technology. A multi-loop magnetic core made of Fe-based amorphous ribbon was employed as the sensing element, and 3-D solenoid copper coils were used to control the sensing core. Antibody-conjugated immunomagnetic microbeads were strategically utilized as signal tags to label the CRP via the specific conjugation of CRP to polyclonal CRP antibodies...
2018: PloS One
https://www.readbyqxmd.com/read/29584633/temperature-and-vibration-dependence-of-the-faraday-effect-of-gd%C3%A2-o%C3%A2-nps-doped-alumino-silicate-glass-optical-fiber
#11
Seongmin Ju, Jihun Kim, Kadathala Linganna, Pramod R Watekar, Seong Gu Kang, Bok Hyeon Kim, Seongjae Boo, Youjin Lee, Yong Ho An, Cheol Jin Kim, Won-Taek Han
All-optical fiber magnetic field sensor based on the Gd₂O₃ nano-particles (NPs)-doped alumino-silicate glass optical fiber was developed, and its temperature and vibration dependence on the Faraday Effect were investigated. Uniformly embedded Gd₂O₃ NPs were identified to form in the core of the fiber, and the measured absorption peaks of the fiber appearing at 377 nm, 443 nm, and 551 nm were attributed to the Gd₂O₃ NPs incorporated in the fiber core. The Faraday rotation angle (FRA) of the linearly polarized light was measured at 650 nm with the induced magnetic field by the solenoid...
March 27, 2018: Sensors
https://www.readbyqxmd.com/read/29545322/the-role-of-heat-tolerant-endotoxin-retentive-ultrafilters-ufs-for-the-remediation-of-reverse-osmosis-ro-plants-employed-for-surgical-hand-antisepsis-using-periodic-thermal-disinfection-a-ten-year-longitudinal-experience-study-in-the-operating-theater
#12
Yushi Uetera, Hiroshi Yasuhara, Naohito Kumada, Yoshiki Misawa, Yoshiyuki Terada, Yoshio Satou, Tamaki Suhara, Kunio Kawamura
Recently, the use of filters has come into light for sanitizing water plants. This study investigated the role of heat-tolerant ultrafilters (UFs) for the remediation of reverse osmosis (RO) plants using periodic thermal disinfection. Two completely identical RO plants (RO plants A & B) were installed in 2006 for surgical hand antisepsis in the operating theater. RO water was stored in the 300-liter storage tank and re-circulated in the 190 meter-long loop delivering water to 12 faucets in each RO plant...
March 15, 2018: PDA Journal of Pharmaceutical Science and Technology
https://www.readbyqxmd.com/read/29534006/research-on-the-factors-influencing-the-measurement-errors-of-the-discrete-rogowski-coil
#13
Mengyuan Xu, Jing Yan, Yingsan Geng, Kun Zhang, Chao Sun
An innovative array of magnetic coils (the discrete Rogowski coil-RC) with the advantages of flexible structure, miniaturization and mass producibility is investigated. First, the mutual inductance between the discrete RC and circular and rectangular conductors are calculated using the magnetic vector potential (MVP) method. The results are found to be consistent with those calculated using the finite element method, but the MVP method is simpler and more practical. Then, the influence of conductor section parameters, inclination, and eccentricity on the accuracy of the discrete RC is calculated to provide a reference...
March 13, 2018: Sensors
https://www.readbyqxmd.com/read/29533528/structure-of-a-bacterial-ice-binding-protein-with-two-faces-of-interaction-with-ice
#14
Marco Mangiagalli, Guy Sarusi, Aleksei Kaleda, Maya Bar Dolev, Valentina Nardone, Vittoria Federica Vena, Ido Braslavsky, Marina Lotti, Marco Nardini
Ice-binding proteins (IBPs) contribute to the survival of many living beings at subzero temperature by controlling the formation and growth of ice crystals. This work investigates the structural basis of the ice-binding properties of EfcIBP, obtained from Antarctic bacteria. EfcIBP is endowed with a unique combination of thermal hysteresis and ice recrystallization inhibition activity. The three-dimensional structure, solved at 0.84 Å resolution, shows that EfcIBP belongs to the IBP-1 fold family, and is organized in a right-handed β-solenoid with a triangular cross-section that forms three protein surfaces, named A, B, and C faces...
May 2018: FEBS Journal
https://www.readbyqxmd.com/read/29508590/-blomia-tropicalis-is-found-in-a-flour-warehouse-of-a-food-factory-in-a-civil-aviation-airport
#15
T Ning, W Shao-Sheng, Y Yan-Feng, Z Yong, L I Chao-Pin
Objective To investigate whether there is Blomia tropicalis breeding in the flour warehouse of food factory in a civil aviation airport, and, if there is, to observe the morphological structure of the mite. Methods The flour samples were collected from the flour warehouse of food factory in a civil aviation airport. The breeding mites were isolated from the samples by direct microscopy and made into specimens to observe with a light microscope. Results Female Blomia tropicalis was found in the collected flour samples...
April 28, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29507249/structural-basis-for-the-role-of-serine-rich-repeat-proteins-from-lactobacillus-reuteri-in-gut-microbe-host-interactions
#16
Saannya Sequeira, Devon Kavanaugh, Donald A MacKenzie, Tanja Šuligoj, Samuel Walpole, Charlotte Leclaire, A Patrick Gunning, Dimitrios Latousakis, William G T Willats, Jesus Angulo, Changjiang Dong, Nathalie Juge
Lactobacillus reuteri , a Gram-positive bacterial species inhabiting the gastrointestinal tract of vertebrates, displays remarkable host adaptation. Previous mutational analyses of rodent strain L. reuteri 100-23C identified a gene encoding a predicted surface-exposed serine-rich repeat protein (SRRP100-23 ) that was vital for L. reuteri biofilm formation in mice. SRRPs have emerged as an important group of surface proteins on many pathogens, but no structural information is available in commensal bacteria...
March 20, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29501151/renewable-chemiluminescence-optosensors-based-on-implementation-of-bead-injection-principle-with-multicommutation
#17
Juan C Domínguez-Romero, Bienvenida Gilbert-López, Miriam Beneito-Cambra, Antonio Molina-Díaz
In this work, the implementation of Bead Injection with multicommutation-based flow systems is reported. A surface renewable chemiluminescence (CL) flow sensor is presented based on the use of CL reaction of luminol with H2 O2 . Dowex 1 × 8 beads with immobilized luminol onto them were injected in the flow system by means of a six-port rotary valve and were accommodated into a 1 mm optical glass flow cell placed just in front of the rectangular photosensor window with the same size than the cell wall. Automatic computer-controlled manipulation of both reagents and sample solutions was undertaken using a multicommutated flow system which comprises five three-way solenoid valves, a home-made electronic interface and a Java-written software...
May 15, 2018: Talanta
https://www.readbyqxmd.com/read/29498209/an-ice-binding-and-tandem-beta-sandwich-domain-containing-protein-in-shewanella-frigidimarina-is-a-potential-new-type-of-ice-adhesin
#18
Tyler D R Vance, Laurie A Graham, Peter L Davies
Out of the dozen different ice-binding protein (IBP) structures known, the DUF3494 domain is the most widespread, having been passed many times between prokaryotic and eukaryotic microorganisms by horizontal gene transfer. This ~25-kDa β-solenoid domain with an adjacent parallel α-helix is most commonly associated with an N-terminal secretory signal peptide. However, examples of the DUF3494 domain preceded by tandem Bacterial Immunoglobulin-like (BIg) domains are sometimes found, though uncharacterized. Here, we present one such protein (SfIBP_1) from the Antarctic bacterium Shewanella frigidimarina...
April 2018: FEBS Journal
https://www.readbyqxmd.com/read/29481217/beam-energy-dependence-of-directed-flow-of-%C3%AE-%C3%AE-over-%C3%A2-k-%C3%A2-k_-s-0-and-%C3%AF-in-au-au-collisions
#19
L Adamczyk, J R Adams, J K Adkins, G Agakishiev, M M Aggarwal, Z Ahammed, N N Ajitanand, I Alekseev, D M Anderson, R Aoyama, A Aparin, D Arkhipkin, E C Aschenauer, M U Ashraf, A Attri, G S Averichev, X Bai, V Bairathi, K Barish, A Behera, R Bellwied, A Bhasin, A K Bhati, P Bhattarai, J Bielcik, J Bielcikova, L C Bland, I G Bordyuzhin, J Bouchet, J D Brandenburg, A V Brandin, D Brown, I Bunzarov, J Butterworth, H Caines, M Calderón de la Barca Sánchez, J M Campbell, D Cebra, I Chakaberia, P Chaloupka, Z Chang, N Chankova-Bunzarova, A Chatterjee, S Chattopadhyay, X Chen, J H Chen, X Chen, J Cheng, M Cherney, W Christie, G Contin, H J Crawford, S Das, L C De Silva, T G Dedovich, J Deng, A A Derevschikov, L Didenko, C Dilks, X Dong, J L Drachenberg, J E Draper, L E Dunkelberger, J C Dunlop, L G Efimov, N Elsey, J Engelage, G Eppley, R Esha, S Esumi, O Evdokimov, J Ewigleben, O Eyser, R Fatemi, S Fazio, P Federic, P Federicova, J Fedorisin, Z Feng, P Filip, E Finch, Y Fisyak, C E Flores, J Fujita, L Fulek, C A Gagliardi, D Garand, F Geurts, A Gibson, M Girard, D Grosnick, D S Gunarathne, Y Guo, A Gupta, S Gupta, W Guryn, A I Hamad, A Hamed, A Harlenderova, J W Harris, L He, S Heppelmann, S Heppelmann, A Hirsch, S Horvat, X Huang, B Huang, T Huang, H Z Huang, T J Humanic, P Huo, G Igo, W W Jacobs, A Jentsch, J Jia, K Jiang, S Jowzaee, E G Judd, S Kabana, D Kalinkin, K Kang, D Kapukchyan, K Kauder, H W Ke, D Keane, A Kechechyan, Z Khan, D P Kikoła, C Kim, I Kisel, A Kisiel, L Kochenda, M Kocmanek, T Kollegger, L K Kosarzewski, A F Kraishan, L Krauth, P Kravtsov, K Krueger, N Kulathunga, L Kumar, J Kvapil, J H Kwasizur, R Lacey, J M Landgraf, K D Landry, J Lauret, A Lebedev, R Lednicky, J H Lee, C Li, X Li, Y Li, W Li, J Lidrych, T Lin, M A Lisa, P Liu, H Liu, Y Liu, F Liu, T Ljubicic, W J Llope, M Lomnitz, R S Longacre, S Luo, X Luo, Y G Ma, L Ma, R Ma, G L Ma, N Magdy, R Majka, D Mallick, S Margetis, C Markert, H S Matis, K Meehan, J C Mei, Z W Miller, N G Minaev, S Mioduszewski, D Mishra, S Mizuno, B Mohanty, M M Mondal, D A Morozov, M K Mustafa, Md Nasim, T K Nayak, J M Nelson, M Nie, G Nigmatkulov, T Niida, L V Nogach, T Nonaka, S B Nurushev, G Odyniec, A Ogawa, K Oh, V A Okorokov, D Olvitt, B S Page, R Pak, Y Pandit, Y Panebratsev, B Pawlik, H Pei, C Perkins, P Pile, J Pluta, K Poniatowska, J Porter, M Posik, N K Pruthi, M Przybycien, J Putschke, H Qiu, A Quintero, S Ramachandran, R L Ray, R Reed, M J Rehbein, H G Ritter, J B Roberts, O V Rogachevskiy, J L Romero, J D Roth, L Ruan, J Rusnak, O Rusnakova, N R Sahoo, P K Sahu, S Salur, J Sandweiss, M Saur, J Schambach, A M Schmah, W B Schmidke, N Schmitz, B R Schweid, J Seger, M Sergeeva, R Seto, P Seyboth, N Shah, E Shahaliev, P V Shanmuganathan, M Shao, A Sharma, M K Sharma, W Q Shen, S S Shi, Z Shi, Q Y Shou, E P Sichtermann, R Sikora, M Simko, S Singha, M J Skoby, N Smirnov, D Smirnov, W Solyst, L Song, P Sorensen, H M Spinka, B Srivastava, T D S Stanislaus, M Strikhanov, B Stringfellow, A A P Suaide, T Sugiura, M Sumbera, B Summa, Y Sun, X M Sun, X Sun, B Surrow, D N Svirida, Z Tang, A H Tang, A Taranenko, T Tarnowsky, A Tawfik, J Thäder, J H Thomas, A R Timmins, D Tlusty, T Todoroki, M Tokarev, S Trentalange, R E Tribble, P Tribedy, S K Tripathy, B A Trzeciak, O D Tsai, T Ullrich, D G Underwood, I Upsal, G Van Buren, G van Nieuwenhuizen, A N Vasiliev, F Videbæk, S Vokal, S A Voloshin, A Vossen, G Wang, Y Wang, F Wang, Y Wang, J C Webb, G Webb, L Wen, G D Westfall, H Wieman, S W Wissink, R Witt, Y Wu, Z G Xiao, G Xie, W Xie, J Xu, Z Xu, Q H Xu, Y F Xu, N Xu, S Yang, Y Yang, C Yang, Q Yang, Z Ye, Z Ye, L Yi, K Yip, I-K Yoo, N Yu, H Zbroszczyk, W Zha, Z Zhang, J B Zhang, J Zhang, S Zhang, Y Zhang, X P Zhang, J Zhang, S Zhang, J Zhao, C Zhong, C Zhou, L Zhou, X Zhu, Z Zhu, M Zyzak
Rapidity-odd directed-flow measurements at midrapidity are presented for Λ, Λ[over ¯], K^{±}, K_{s}^{0}, and ϕ at sqrt[s_{NN}]=7.7, 11.5, 14.5, 19.6, 27, 39, 62.4, and 200 GeV in Au+Au collisions recorded by the Solenoidal Tracker detector at the Relativistic Heavy Ion Collider. These measurements greatly expand the scope of data available to constrain models with differing prescriptions for the equation of state of quantum chromodynamics. Results show good sensitivity for testing a picture where flow is assumed to be imposed before hadron formation and the observed particles are assumed to form via coalescence of constituent quarks...
February 9, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29466333/the-cryo-electron-microscopy-structure-of-huntingtin
#20
Qiang Guo, Bin Huang, Jingdong Cheng, Manuel Seefelder, Tatjana Engler, Günter Pfeifer, Patrick Oeckl, Markus Otto, Franziska Moser, Melanie Maurer, Alexander Pautsch, Wolfgang Baumeister, Rubén Fernández-Busnadiego, Stefan Kochanek
Huntingtin (HTT) is a large (348 kDa) protein that is essential for embryonic development and is involved in diverse cellular activities such as vesicular transport, endocytosis, autophagy and the regulation of transcription. Although an integrative understanding of the biological functions of HTT is lacking, the large number of identified HTT interactors suggests that it serves as a protein-protein interaction hub. Furthermore, Huntington's disease is caused by a mutation in the HTT gene, resulting in a pathogenic expansion of a polyglutamine repeat at the amino terminus of HTT...
March 1, 2018: Nature
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