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Long-term outcomes

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https://www.readbyqxmd.com/read/28107766/long-term-clinical-outcomes-of-endoscopic-submucosal-dissection-for-colorectal-neoplasms-in-423-cases-a-retrospective-study
#1
Masayoshi Yamada, Yutaka Saito, Hiroyuki Takamaru, Hayato Sasaki, Takuya Yokota, Yasushi Matsuyama, Yoshinori Sato, Taku Sakamoto, Takeshi Nakajima, Hirokazu Taniguchi, Shigeki Sekine, Takahisa Matsuda
Background and study aim Endoscopic submucosal dissection (ESD) is known as a curative treatment for colorectal superficial neoplasms. There is however a need for more long-term clinical data to establish the full advantages of colorectal ESD regarding very low recurrence rates. The aim of this retrospective study was to determine long-term clinical outcomes of colorectal ESD. Methods A total of 423 lesions treated by ESD for colorectal adenoma/dysplasia or adenocarcinoma between 1998 and 2008 at a single high volume referral center were included...
January 20, 2017: Endoscopy
https://www.readbyqxmd.com/read/28107673/mri-patterns-of-brain-injury-and-neurodevelopmental-outcomes-in-neonates-with-severe-anaemia-at-birth
#2
Begoña Loureiro, Miriam Martinez-Biarge, Francesca Foti, Maria Papadaki, Frances M Cowan, Courtney J Wusthoff
AIMS: To define patterns of brain injury and associated neurodevelopmental outcomes in infants with severe neonatal anaemia. METHODS: We studied 20 infants with severe anaemia at birth (haemoglobin<7g/dL). Clinical details were analysed for causes of anaemia and co-morbidities. All had early brain magnetic resonance imaging (MRI) scans, which were reviewed for injury pattern. Neurodevelopmental outcomes were assessed at a median age of 24months. RESULTS: The aetiology of the anaemia was feto-maternal haemorrhage in 17 and antepartum haemorrhage in 3 infants...
January 17, 2017: Early Human Development
https://www.readbyqxmd.com/read/28107561/beta-blockers-for-hypertension
#3
REVIEW
Charles S Wiysonge, Hazel A Bradley, Jimmy Volmink, Bongani M Mayosi, Lionel H Opie
BACKGROUND: Beta-blockers refer to a mixed group of drugs with diverse pharmacodynamic and pharmacokinetic properties. They have shown long-term beneficial effects on mortality and cardiovascular disease (CVD) when used in people with heart failure or acute myocardial infarction. Beta-blockers were thought to have similar beneficial effects when used as first-line therapy for hypertension. However, the benefit of beta-blockers as first-line therapy for hypertension without compelling indications is controversial...
January 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28107402/risk-factors-for-postoperative-pain-intensity-in-patients-undergoing-lumbar-disc-surgery-a-systematic-review
#4
Marie Dorow, Margrit Löbner, Janine Stein, Alexander Konnopka, Hans J Meisel, Lutz Günther, Jürgen Meixensberger, Katarina Stengler, Hans-Helmut König, Steffi G Riedel-Heller
OBJECTIVES: Pain relief has been shown to be the most frequently reported goal by patients undergoing lumbar disc surgery. There is a lack of systematic research investigating the course of postsurgical pain intensity and factors associated with postsurgical pain. This systematic review focuses on pain, the most prevalent symptom of a herniated disc as the primary outcome parameter. The aims of this review were (1) to examine how pain intensity changes over time in patients undergoing surgery for a lumbar herniated disc and (2) to identify socio-demographic, medical, occupational and psychological factors associated with pain intensity...
2017: PloS One
https://www.readbyqxmd.com/read/28107377/hbeag-seroconversion-in-hbeag-positive-chronic-hepatitis-b-patients-receiving-long-term-nucleos-t-ide-analog-treatment-a-systematic-review-and-network-meta-analysis
#5
Tongjing Xing, Hongtao Xu, Lin Cao, Maocong Ye
BACKGROUND: HBeAg seroconversion is an important intermediate outcome in HBeAg-positive chronic hepatitis B (CHB) patients. This study aimed to compare the effect of nucleos(t)ide analogs (NAs) on HBeAg seroconversion in treating CHB with lamivudine, adefovir, telbivudine, entecavir, and tenofovir. METHODS: Network meta-analysis of NA treatment-induced HBeAg seroconversion after 1-2 years of treatment was performed. In addition, NA treatment-induced HBeAg seroconversion after 3-5 years of treatment was systematically evaluated...
2017: PloS One
https://www.readbyqxmd.com/read/28107317/photography-in-telemedicine-improving-diagnosis-of-chronic-graft-versus-host-disease%C3%A2
#6
Brianna Busby, Shannon Campbell, Rachel Cole, Charisse DeVries, Kamille Dobbins, Mary Beth Trimble, Mihkaila Wickline
BACKGROUND: The long-term follow-up (LTFU) team at the Seattle Cancer Care Alliance uses telemedicine to diagnose and treat post-transplantation complications in hematopoietic cell transplantation (HCT) survivors. Photos are often requested via the telemedicine service to aid in diagnosis, but they are typically of poor quality, making them unusable.
. OBJECTIVES: This project offered bachelor of science in nursing students, partnered with a comprehensive cancer center, the opportunity to participate in an evidence-based practice project to improve detection and management of chronic graft-versus-host disease (cGVHD) in patients after HCT...
February 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28107265/long-term-function-after-pediatric-critical-illness-results-from-the-survivor-outcomes-study
#7
Neethi P Pinto, Elizabeth W Rhinesmith, Tae Yeon Kim, Peter H Ladner, Murray M Pollack
OBJECTIVE: Knowledge of the long-term outcomes of survivors of pediatric critical illness is sparse but important. The aim of this study was to evaluate morbidity and mortality 6 months and 3 years after hospital discharge. DESIGN: Prospective cohort study. SETTING: Urban, inner city, academic PICU. PATIENTS: Consecutive patients admitted to the PICU from June 2012 to August 2012. INTERVENTIONS: None...
January 19, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28107220/treatment-of-primary-acute-patellar-dislocation-systematic-review-and-quantitative-synthesis-of-the-literature
#8
Umile Giuseppe Longo, Mauro Ciuffreda, Joel Locher, Alessandra Berton, Giuseppe Salvatore, Vincenzo Denaro
PURPOSE: The aim of this study was to evaluate clinical outcomes, rate of redislocation, and complications after conservative or surgical procedures used to treat primary acute patellar dislocation. METHODS: A comprehensive search of PubMed, Medline, CINAHL, Cochrane, Embase, and Google Scholar databases using various combinations of the keywords "patella," "dislocation," "treatment," "acute," "primary" was performed. The following data were extracted: demographics, chondral defects and soft tissue lesions, outcome measurements, type of management, recurrence of instability, and complications...
January 17, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28107168/the-natriuretic-peptide-mr-proanp-predicts-all-cause-mortality-and-adverse-outcome-in-community-patients-a-10-year-follow-up-study
#9
Jonas Odermatt, Lara Hersberger, Rebekka Bolliger, Lena Graedel, Mirjam Christ-Crain, Matthias Briel, Heiner C Bucher, Beat Mueller, Philipp Schuetz
BACKGROUND: The precursor peptide of atrial natriuretic peptide (MR-proANP) has a physiological role in fluid homeostasis and is associated with mortality and adverse clinical outcomes in heart failure patients. Little is known about the prognostic potential of this peptide for long-term mortality prediction in community-dwelling patients. We evaluated associations of MR-proANP levels with 10-year all-cause mortality in patients visiting their general practitioner for a respiratory tract infection...
January 20, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28106893/long-term-outcome-of-conjunctival-fixation-sutures-to-the-sclera-for-prolapsed-subconjunctival-orbital-fat
#10
M K Yang, N Kim, H-K Choung, S I Khwarg
PurposeTo report long-term outcome of new surgical technique for prolapsed subconjunctival orbital fat.Patients and methodsRetrospective study was conducted on 48 eyes of 37 patients who underwent excision of prolapsed subconjunctival orbital fat with conjunctival fixation to the sclera. Complications and recurrence were evaluated.ResultsThe mean follow-up period was 39 months (range, 8-101 months). Two eyes (4.4%) developed recurrence at 4 and 8 years after surgery. No long-term complication was found.ConclusionsThe new surgical technique to manage prolapsed subconjunctival orbital fat using conjunctival fixation to the sclera was very useful and effective, with few recurrence and no long-term complication...
January 20, 2017: Eye
https://www.readbyqxmd.com/read/28106887/report-of-12-months-efficacy-and-safety-of-intravitreal-fluocinalone-acetonide-implant-for-the-treatment-of-chronic-diabetic-macular-oedema-a-real-world-result-in-the-united-kingdom
#11
F Alfaqawi, P L Lip, S Elsherbiny, R Chavan, A Mitra, B Mushtaq
: PurposeTo report the 12-months visual and anatomical outcomes of chronic diabetic macular oedema (DMO) treated with ILUVIEN in a real-world clinical practice in a single tertiary referral centre.MethodRetrospective data collection and analysis of consecutive 28 eyes of 23 diabetic patients received ILUVIEN implant for refractory DMO. Standard assessment included visual acuity (VA), central retinal thickness (CRT), slit-lamp biomicroscopy, and Goldmann tonometry for intraocular pressure (IOP) at 1, 6, and 12 months...
January 20, 2017: Eye
https://www.readbyqxmd.com/read/28106674/open-surgical-release-of-posttraumatic-elbow-contracture-in-children-and-adolescents
#12
Samantha L Piper, Lisa L Lattanza, Tony S Shen, Lindley B Wall, Charles A Goldfarb
BACKGROUND: Posttraumatic elbow contractures in children and adolescents are challenging to manage, and studies investigating surgical treatment are limited by the rarity of this condition. Small case series have shown variable gains in immediate and long-term elbow arc of motion after open surgical release. We reviewed our experience with open surgical release of posttraumatic elbow contracture in patients <21 years old at 2 institutions. METHODS: A retrospective chart review identified patients who underwent posttraumatic open elbow contracture release by 2 surgeons at 2 institutions between 2006 and 2013...
January 18, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28106669/translational-studies-identify-long-term-impact-of-prior-neonatal-pain-experience
#13
Suellen M Walker
Pain sensitivity and risk of chronic pain can be influenced by past experience. Childhood stress/adversity has been associated with chronic pain, mood disorders, and altered disease vulnerability decades later. As the rate of preterm birth and survival at earlier gestational ages increases, and advances in peri-operative care and surgery allow more complex surgical interventions to be performed in neonates, evaluation of treatment 'success' must extend beyond acute morbidity and mortality to encompass effects on subsequent neurodevelopmental outcome, and also sensory, cognitive and behavioral responses to pain in later life...
January 12, 2017: Pain
https://www.readbyqxmd.com/read/28106659/adenoid-cystic-carcinoma-evaluation-and-management-progress-with-optimism
#14
Patrick J Bradley
PURPOSE OF REVIEW: Adenoid cystic carcinoma (ACC) when diagnosed presents several diagnostic and treatment challenges. The standard treatment of surgery and postoperative radiotherapy has remained the standard of care for the past 3 decades. The purpose of this review is to update what's been reported and what's new since the last review in 2004. RECENT FINDINGS: As accurate a histological diagnosis and staging of disease should be achieved prior to commencing any treatment...
January 18, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28106625/long-term-hearing-results-after-ossiculoplasty
#15
Matthew D Cox, Aaron Trinidade, James Shep Russell, John L Dornhoffer
OBJECTIVES: To determine if the OOPS index is predictive of long-term hearing results after ossiculoplasty. STUDY DESIGN: Case series with retrospective chart review. SETTING: Tertiary care otology practice. PATIENTS: Adult and pediatric patients (3-88 years of age). INTERVENTIONS: Ossiculoplasty with cartilage tympanoplasty, with or without mastoidectomy. OUTCOME MEASURES: Primary outcome measures included short-term hearing results (pure-tone average air-bone gap [PTA-ABG] measured between 60 days and 1 year after surgery), long-term hearing results (PTA-ABG measured ≥5 years after surgery), and the rate of successful ABG closure to ≤20 dB...
January 18, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28106513/long-term-follow-up-of-superior-gluteal-artery-perforator-flap-closure-of-large-myelomeningoceles
#16
Brett A Whittemore, Dale M Swift, Bradley E Weprin, Frederick J Duffy
OBJECTIVE Large myelomeningocele defects and poor surrounding tissue quality make some defects particularly difficult to close primarily. This paper describes the superior gluteal artery perforator (SGAP) flap technique for defect closure and long-term clinical outcomes. METHODS The technique for closing a myelomeningocele with an SGAP flap is described. A retrospective chart review was performed on a cohort of 11 patients who underwent closure in this manner. RESULTS Between 1999 and 2015, 271 myelomeningoceles were closed, 11 of which were SGAP flap closures...
January 20, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28106499/retrospective-study-of-long-term-outcome-after-brain-arteriovenous-malformation-rupture-the-rap-score
#17
Eimad Shotar, Matthieu Debarre, Nader-Antoine Sourour, Federico Di Maria, Joseph Gabrieli, Aurélien Nouet, Jacques Chiras, Vincent Degos, Frédéric Clarençon
OBJECTIVE The authors aimed to design a score for stratifying patients with brain arteriovenous malformation (BAVM) rupture, based on the likelihood of a poor long-term neurological outcome. METHODS The records of consecutive patients with BAVM hemorrhagic events who had been admitted over a period of 11 years were retrospectively reviewed. Independent predictors of a poor long-term outcome (modified Rankin Scale score ≥ 3) beyond 1 year after admission were identified. A risk stratification scale was developed and compared with the intracranial hemorrhage (ICH) score to predict poor outcome and inpatient mortality...
January 20, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28106463/long-term-results-after-arthroscopic-repair-of-isolated-subscapularis-tears
#18
Gernot Seppel, Johannes E Plath, Christopher Völk, Wolfgang Seiberl, Stefan Buchmann, Simone Waldt, Andreas B Imhoff, Sepp Braun
BACKGROUND: Although some reports have presented short- to midterm results after arthroscopic repair of isolated subscapularis (SSC) tendon tears, long-term evaluation is still lacking. HYPOTHESIS: Long-term results after arthroscopic repair of isolated SSC tears are comparable with the functional and radiological short- to midterm outcomes described in the literature. STUDY DESIGN: Case series, Level of evidence, 4. METHODS: This study assessed 17 patients (5 females and 12 males; mean age, 45...
December 1, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28106235/scleral-buckling-in-phakic-uncomplicated-primary-rhegmatogenous-retinal-detachment-long-term-outcomes
#19
Claudia Quijano, Micol Alkabes, Maria Gómez-Resa, Andrea Oleñik, Edoardo Villani, Borja Corcóstegui
PURPOSE: Scleral buckling (SB) is a surgical technique that has been used successfully to treat retinal detachments for the last 6 decades. The aim of this study was to report the long-term anatomical and functional outcomes of SB surgery in phakic patients with uncomplicated primary rhegmatogenous retinal detachment (PRRD). This article also outlines the benefits of SB compared to pars plana vitrectomy, such as reducing the risk of developing cataract, high intraocular pressure, and glaucoma, in addition to reducing surgical cost...
December 31, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28106151/obesity-assessing-the-long-term-outcomes-of-bariatric-surgery-in-adolescents
#20
Claire Greenhill
No abstract text is available yet for this article.
January 20, 2017: Nature Reviews. Endocrinology
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