keyword
MENU ▼
Read by QxMD icon Read
search

Bioactive glass

keyword
https://www.readbyqxmd.com/read/28220167/dynamical-descriptors-of-bioactivity-a-correlation-between-chemical-durability-and-ion-migration-in-biodegradable-glasses
#1
Antonio Tilocca
Ion migration in two fluorinated bioactive glasses of significantly different durability was modeled through molecular dynamics simulations. Whereas the very different biodegradation of these glasses cannot be explained on the basis of their structural features alone, the analysis of the diffusive data highlights a strong connection between the glass durability determined experimentally and the activation barriers for ion diffusion extracted by the simulations, clarifying the source of the different solubility and suggesting that "dynamical" descriptors of bioactivity could represent a key tool to predict the macroscopic behavior of a biomaterial, in some cases more effectively than with the current structural descriptors...
February 21, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28219807/setd2-is-associated-with-strontium-induced-bone-regeneration
#2
Jia Xiaoshi, Long Qiaoyun, Richard J Miron, Yin Chengcheng, Wei Yan, Zhang Yufeng, Wu Min
: Strontium Ranelate has been utilized as a preventative treatment option for osteoporosis with the release of Sr ions having a direct effect on preventing osteoclast activation and promoting osteoblast differentiation. Previously our group has prepared and characterized a porous Sr-mesoporous bioactive glass (Sr-MBG) scaffold demonstrating its ability to enhance new bone formation when compared to MBG alone. The goal of the present study was to elucidate the bone-inducing properties of Sr by utilizing RNA-seq on in vivo tissue samples to investigate potential target genes responsible for Sr-induced new bone formation...
February 17, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28219056/anticaries-potential-of-a-sodium-monofluorophosphate-dentifrice-containing-calcium-sodium-phosphosilicate-exploratory-in-situ-randomized-trial
#3
Charles R Parkinson, Muhammad Siddiqi, Stephen Mason, Frank Lippert, Anderson T Hara, Domenick T Zero
Calcium sodium phosphosilicate (CSPS) is a bioactive glass material that alleviates dentin hypersensitivity and is postulated to confer remineralization of caries lesions. This single-centre, randomized, single (investigator)-blind, placebo-controlled, crossover, in situ study explored whether the addition of 5% CSPS to a nonaqueous fluoride (F) such as sodium monofluorophosphate (SMFP)-containing dentifrice affects its cariostatic ability. Seventy-seven subjects wore 4 gauze-covered enamel specimens with preformed lesions (2 surface-softened and 2 subsurface) placed buccally on their mandibular bilateral dentures for up to 4 weeks...
February 21, 2017: Caries Research
https://www.readbyqxmd.com/read/28211911/three-dimensional-printing-of-calcium-sulfate-and-mesoporous-bioactive-glass-scaffolds-for-improving-bone-regeneration-in-vitro-and-in-vivo
#4
Xin Qi, Peng Pei, Min Zhu, Xiaoyu Du, Chen Xin, Shichang Zhao, Xiaolin Li, Yufang Zhu
In the clinic, bone defects resulting from infections, trauma, surgical resection and genetic malformations remain a significant challenge. In the field of bone tissue engineering, three-dimensional (3D) scaffolds are promising for the treatment of bone defects. In this study, calcium sulfate hydrate (CSH)/mesoporous bioactive glass (MBG) scaffolds were successfully fabricated using a 3D printing technique, which had a regular and uniform square macroporous structure, high porosity and excellent apatite mineralization ability...
February 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28209033/in-vitro-investigation-of-bioactive-glass-ceramic-composites-based-on-biogenic-hydroxyapatite-or-synthetic-calcium-phosphates
#5
Nataliia Pinchuk, Oleksandr Parkhomey, Olena Sych
This in vitro investigation of the behavior of two types of calcium phosphate glass ceramics on the basis of phosphates of biogenic or synthetic origin prepared from initial mixtures with different particle size has revealed that some different factors affect the behavior, namely the phase composition of composite, fraction of open porosity, and average diameter of pore channels. It was established that the solubility of the composites on the basis of synthetic calcium phosphates and glass after 2 and 7 days contact with saline composites is the highest among the materials under study...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28207249/convection-driven-pull-down-assays-in-nanoliter-droplets-using-scaffolded-aptamers
#6
Xiangmeng Qu, Hongbo Zhang, Hong Chen, Ali Aldalbahi, Li Li, Yang Tian, David A Weitz, Hao Pei
One of the great challenges in cellular studies is to develop a rapid and biocompatible analytical tool for single-cell analysis. We report a rapid, DNA nanostructure-supported aptamer pull-down (DNaPull) assay under convective flux in a glass capillary for analyzing contents of droplets with nano or picoliter volumes. We have demonstrated that the scaffolded aptamer can greatly improve the efficiency of target molecules' pull-down. The convective flux enables complete reaction in less than 5 min, which is an 18-fold improvement compared to purely diffusive flux (traditional model of stationary case)...
February 16, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28205372/zein-based-composites-in-biomedical-applications
#7
Merve Demir, Laura Ramos-Rivera, Raquel Silva, Showan N Nazhat, Aldo R Boccaccini
Considerable research efforts have been devoted to zein based biomaterials for tissue engineering and other biomedical applications over the past decade. The attention given to zein based polymers is primarily attributed to their biocompatibility and biodegradability. However, due to the relatively low mechanical properties of these polymers, numerous inorganic compounds (e.g, hydroxyapatite, calcium phosphate, bioactive glasses, natural clays) have been considered in combination with zein to create composite materials in an attempt to enhance zein mechanical properties...
February 16, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28197990/a-chlorhexidine-releasing-epoxy-based-coating-on-titanium-implants-prevents-staphylococcus-aureus-experimental-biomaterial-associated-infection
#8
M Riool, A J Dirks, V Jaspers, L de Boer, T J Loontjens, C M van der Loos, S Florquin, I Apachitei, L N Rijk, H A Keul, S A Zaat
Prevention of biomaterial-associated infections (BAI) remains a challenging problem, in particular due to the increased risk of resistance development with the current antibiotic-based strategies. Metallic orthopaedic devices, such as non-cemented implants, are often inserted under high mechanical stress. These non-cemented implants cannot be protected by e.g. antibioticreleasing bone cement or other antimicrobial approaches, such as the use of bioactive glass. Therefore, in order to avoid abrasion during implantation procedures, we developed an antimicrobial coating with great mechanical stability for orthopaedic implants, to prevent Staphylococcus aureus BAI...
February 14, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/28196604/addition-of-bioactive-glass-to-glass-ionomer-cements-effect-on-the-physico-chemical-properties-and-biocompatibility
#9
T De Caluwé, C W J Vercruysse, I Ladik, R Convents, H Declercq, L C Martens, R M H Verbeeck
OBJECTIVES: Glass ionomer cements (GICs) are a subject of research because of their inferior mechanical properties, despite their advantages such as fluoride release and direct bonding to bone and teeth. Recent research aims to improve the bioactivity of the GICs and thereby improve mechanical properties on the long term. In this study, two types of bioactive glasses (BAG) (45S5F and CF9) are combined with GICs to evaluate the physico-chemical properties and biocompatibility of the BAG-GIC combinations...
February 10, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28190815/structural-analysis-of-strontium-in-human-teeth-treated-with-surface-pre-reacted-glass-ionomer-filler-eluate-by-using-extended-x-ray-absorption-fine-structure-analysis
#10
Motohiro Uo, Takahiro Wada, Kiyotaka Asakura
The bioactive effects of strontium released from surface pre-reacted glass-ionomer (S-PRG) fillers may aid in caries prevention. In this study, the local structure of strontium taken up by teeth was estimated by extended X-ray absorption fine structure analysis. Immersing teeth into S-PRG filler eluate increased the strontium content in enamel and dentin by more than 100 times. The local structure of strontium in enamel and dentin stored in distilled water was the same as that in synthetic strontium-containing hydroxyapatite (SrHAP)...
February 11, 2017: Dental Materials Journal
https://www.readbyqxmd.com/read/28187505/study-of-the-dual-effect-of-gamma-irradiation-and-strontium-substitution-on-bioactivity-cytotoxicity-and-antimicrobial-properties-of-45s5-bioglass
#11
M M Farag, W M Abd-Allah, Hanaa Y A Ahmed
In this work, we studied simultaneous effect of gamma irradiation and SrO substitution for Na2 O on bioactivity, cytotoxicity and antimicrobial properties of 45S5 glass. Gamma irradiation was mainly introduced in this work as an effective sterilizing technique, improvement of bulk properties and surface modification of glass. Where, gamma irradiation is considered a modifier for glass network due to generation of defects resulted from this irradiation. Furthermore, SrO was introduced into the glass structure in place of Na2 O in order to reduce a probable toxic effect of Na2 O for surrounding tissue by decreasing its percentage...
February 10, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28183672/in-vitro-biocompatibility-of-a-ferrimagnetic-glass-ceramic-for-hyperthermia-application
#12
Oana Bretcanu, Marta Miola, Claudia L Bianchi, Ida Marangi, Roberta Carbone, Ingrid Corazzari, Mario Cannas, Enrica Verné
Ferrimagnetic glass-ceramics containing magnetite crystals were developed for hyperthermia applications of solid neoplastic tissue. The present work is focused on in vitro evaluation of the biocompatibility of these materials, before and after soaking in a simulated body fluid (SBF). X-ray diffraction, scanning electron microscopy, atomic absorption spectrophotometry, X-ray photoelectron spectrometry and pH measurements were employed in glass-ceramic characterisation. The free-radical mediated reactivity of the glass-ceramic was evaluated by Electron Paramagnetic Resonance (EPR) spin trapping...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28183648/evaluation-of-an-injectable-bioactive-borate-glass-cement-to-heal-bone-defects-in-a-rabbit-femoral-condyle-model
#13
Xu Cui, Wenhai Huang, Yadong Zhang, Chengcheng Huang, Zunxiong Yu, Lei Wang, Wenlong Liu, Ting Wang, Jie Zhou, Hui Wang, Nai Zhou, Deping Wang, Haobo Pan, Mohamed N Rahaman
There is a need for synthetic biomaterials to heal bone defects using minimal invasive surgery. In the present study, an injectable cement composed of bioactive borate glass particles and a chitosan bonding solution was developed and evaluated for its capacity to heal bone defects in a rabbit femoral condyle model. The injectability and setting time of the cement in vitro decreased but the compressive strength increased (8±2MPa to 31±2MPa) as the ratio of glass particles to chitosan solution increased (from 1...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28183631/in-vitro-stimulation-of-vascular-endothelial-growth-factor-by-borate-based-glass-fibers-under-dynamic-flow-conditions
#14
Sisi Chen, Qingbo Yang, Richard K Brow, Kun Liu, Katherine A Brow, Yinfa Ma, Honglan Shi
Bioactive borate glass has been recognized to have both hard and soft tissue repair and regeneration capabilities through stimulating both osteogenesis and angiogenesis. However, the underlying biochemical and cellular mechanisms remain unclear. In this study, dynamic flow culturing modules were designed to simulate the micro-environment near the vascular depletion and hyperplasia area in wound-healing regions, thus to better investigate the mechanisms underlying the biocompatibility and functionality of borate-based glass materials...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28181432/mimicking-hierarchical-complexity-of-the-osteochondral-interface-using-electrospun-silk-bioactive-glass-composites
#15
Joseph Christakiran M, Philip James Thomas Reardon, Rocktotpal Konwarh, Jonathan C Knowles, Biman B Mandal
The anatomical complexity and slow regeneration capacity of hyaline cartilage at the osteochondral interface pose a great challenge in the repair of osteochondral defects (OCD). In this study, we utilized the processing feasibility offered by the sol derived 70S bioactive glass and silk fibroin (mulberry Bombyx mori and endemic Indian non-mulberry Antheraea assama), in fabricating a well-integrated, biomimetic scaffolding matrix with a coherent interface. Differences in surface properties such as wettability and amorphousness between the two silk groups resulted in profound variations in cell attachment and extracellular matrix protein deposition...
February 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28154869/calcium-phosphate-bone-cement-mesoporous-bioactive-glass-composites-for-controlled-growth-factor-delivery
#16
M Schumacher, L Reither, J Thomas, M Kampschulte, U Gbureck, A Lode, M Gelinsky
Calcium phosphate (CaP) bone cements are widely used for the treatment of bone defects and have been proposed to serve as a delivery platform for therapeutic drugs, proteins and growth factors into the defect region. However, they lack sufficient porosity to allow immediate bone ingrowth and thus foster rapid integration into the bone tissue. In this study we investigated a composite prepared from a hydroxyapatite forming bone cement and mesoporous bioactive glass (MBG) granules as a potential carrier for biologically active proteins...
February 3, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28152268/the-impact-of-gallium-content-on-degradation-bioactivity-and-antibacterial-potency-of-zinc-borate-bioactive-glass
#17
Alireza Rahimnejad Yazdi, Lawrence Torkan, Wendy Stone, Mark R Towler
Zinc borate glasses with increasing gallium content (0, 2.5, 5, 10, and 15 Wt % Ga) were synthesized and their degradation, bioactivity in simulated body fluid (SBF), and antibacterial properties were investigated. ICP measurements showed that increased gallium content in the glass resulted in increased gallium ion release and decreased release of other ions. Degradability declined with the addition of gallium, indicating the formation of more symmetric BO3 units with three bridging oxygens and asymmetric BO3 units with two bridging oxygens in the glass network as the gallium content in the series increased...
February 2, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28152262/structural-analysis-of-fluorine-containing-bioactive-glass-nanoparticles-synthesized-by-sol-gel-route-assisted-by-ultrasound-energy
#18
Carolina E C Lins, Agda A R Oliveira, Ismael Gonzalez, Waldemar A A Macedo, Marivalda M Pereira
In the last decades, studies about the specific effects of bioactive glass on remineralization of dentin were the focus of attention, due to their excellent regenerative properties in mineralized tissues. The incorporation of Fluorine in bioactive glass nanoparticles may result in the formation of fluorapatite (FAP), which is chemically more stable than hydroxyapatite or carbonated hydroxyapatite, and therefore is of interest for dental applications. The aim of this study was to synthesize and characterize a new system of Fluorine-containing bioactive glass nanoparticles (BGNPF)...
February 2, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28140347/properties-of-cao-sio2-p2o5-reinforced-calcium-phosphate-cements-and-in-vitro-osteoblast-response
#19
Lubomir Medvecky, Radoslava Stulajterova, Tibor Sopcak, Maria Giretova, Maria Faberova
Non-cytotoxic and bioactive tetracalcium phosphate/nanomonetite/calcium silicate-phosphate cements were prepared by simple mechanical mixing of starting powder precursors based on acid or basic tetracalcium phosphate/nanomonetite mixtures with 1 or 5 wt % addition of precititated amorphous or crystalline calcium silicate phosphate phases. The small additions (1-2 wt%) of crystalline CaSiP phase caused about a two-fold rise in the compressive strength of cements (up to 70 MPa) with simultaneous preservation of short setting time (around 5 minutes) and refinement of nanohydroxyapatite particles in microstructure...
January 31, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28135640/characterization-of-the-mechanical-behaviors-and-bioactivity-of-tetrapod-zno-whiskers-reinforced-bioactive-glass-gelatin-composite-scaffolds
#20
Weihuang Guo, Fujian Zhao, Yudong Wang, Jieyin Tang, Xiaofeng Chen
The purpose of this study is to construct bone tissue engineering scaffold with high porosity, good mechanical properties, and biological activities. Bioactive glass/gelatin composite scaffolds with different amounts of tetrapod zinc oxide whiskers were produced. The morphology, mechanical properties and in vitro bioactivity of the composite scaffolds were investigated. Results showed that, the composite scaffolds had open pores with a high degree of interconnectivity, and the porosity was higher than 80%. With the amount of ZnO whiskers increased, the mechanical properties of scaffolds increased...
January 23, 2017: Journal of the Mechanical Behavior of Biomedical Materials
keyword
keyword
102358
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"