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Bioactive glass

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https://www.readbyqxmd.com/read/28921832/synthesis-and-bioactivity-assessment-of-high-silica-content-quaternary-glasses-with-ca-p-ratios-of-1-5-and-1-67-made-by-a-rapid-sol-gel-process
#1
Basam A E Ben-Arfa, Hugo R Fernandes, Isabel M Miranda Salvado, José M F Ferreira, Robert C Pullar
Sol-gel glasses in quaternary silica-sodium-calcium-phosphorous systems have been synthesised using a rotary evaporator for rapid drying without ageing. This novel fast drying method drastically decreases the total drying and ageing time from several weeks to only 1 hour, thus overcoming a serious drawback in sol-gel preparation procedures for bioglasses. This work investigates the bioactivity behaviour of two glasses synthesised by this fast method, with Ca:P ratios of 1.5, and 1.67. X-ray diffraction (XRD), Inductive coupled plasma (ICP), Fourier-transform infrared (FTIR) and Raman spectroscopy were used to confirm the bioactivity of the synthesised powders...
September 16, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28905286/role-of-phase-separation-on-the-biological-performance-of-45s5-bioglass-%C3%A2
#2
Tia J Kowal, Roman Golovchak, Tanuj Chokshi, Joseph Harms, Ukrit Thamma, Himanshu Jain, Matthias M Falk
We analyzed the biological performance of spinodally and droplet-type phase-separated 45S5 Bioglass(®) generated by quenching the melt from different equilibrium temperatures. MC3T3-E1 pre-osteoblast cells attached more efficiently to 45S5 Bioglass® with spinodal than to the one with droplet morphology, providing the first demonstration of the role of micro-/nano-scale on the bioactivity of Bioglass®. Upon exposure to biological solutions, phosphate buffered saline (PBS) and cell culture medium (α-MEM), a layer of hydroxyapatite (HA) formed on both glass morphologies...
September 13, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28902637/development-of-fish-collagen-bioactive-glass-chitosan-composite-nanofibers-as-a-gtr-gbr-membrane-for-inducing-periodontal-tissue-regeneration
#3
Tian Zhou, Xin Liu, Baiyan Sui, Chao Liu, Xiumei Mo, Jiao Sun
The development of a guided tissue or bone regeneration (GTR/GBR) membrane with excellent performance has been a major challenge in the biomedical field. The present study was designed to prepare a biomimetic electrospun fish collagen/bioactive glass/chitosan (Col/BG/CS) composite nanofiber membrane and determine its structure, mechanical property, antibacterial activity, and biological effects on human periodontal ligament cells (HPDLCs). The effects of this composite membrane on inducing periodontal tissue regeneration were evaluated using a dog class II furcation defect model...
September 13, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28893033/comparative-evaluation-of-bioactive-glass-putty-and-platelet-rich-fibrin-in-the-treatment-of-human-periodontal-intrabony-defects-a-randomized-control-trial
#4
Akbar Naqvi, D Gopalakrishnan, Meenu Taneja Bhasin, Nilima Sharma, Khushtar Haider, Santosh Martande
INTRODUCTION: Platelet-Rich Fibrin (PRF) and bioactive glass putty have been shown to be effective in promoting reduction in probing depth, gain in clinical attachment, and defect fill in intrabony periodontal defects. The individual role played by bioactive glass putty in combination with PRF is yet to be elucidated. AIM: To compare the clinical effectiveness of the combination of PRF and bioactive glass putty and bioactive glass putty alone as regenerative techniques for intrabony defects in humans...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28876931/medium-range-structural-organization-of-phosphorus-bearing-borosilicate-glasses-revealed-by-advanced-solid-state-nmr-experiments-and-md-simulations-consequences-of-b-si-substitutions
#5
Yang Yu, Baltzar Stevensson, Mattias Edén
The short and intermediate range structures of a large series of bioactive borophosphosilicate (BPS) glasses were probed by solid-state nuclear magnetic resonance (NMR) spectroscopy and atomistic molecular dynamics (MD) simulations. Two BPS glass series were designed by gradually substituting SiO₂ by B₂O₃ in the respective phosphosilicate base compositions 24.1Na₂O--23.3CaO--48.6SiO₂--4.0P₂O₅ ("S49") and 24.6Na₂O--26.7CaO--46.1SiO₂--2.6P₂O₅ ("S46"), the latter constituting the "45S5 Bioglass" utilized for bone grafting applications...
September 6, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28873728/development-and-characterization-of-a-new-encapsulating-agent-from-orange-juice-by-products
#6
Kyriakos Kaderides, Athanasia M Goula
The replacement of maltodextrins as carriers for the spray drying of sticky and sugar based bioactives is an important development for the food industry. In this work, orange juice industry by-product was used to obtain a high dietary fiber powder to be used as carrier material. This powder was characterized with respect to its physical and chemical properties related to the process of encapsulation by spray drying. Adsorption isotherms of orange waste powder were determined at 30, 45, and 60°C. The data were fitted to several models including two-parameter (BET, Halsey, Smith, and Oswin), three-parameter (GAB), and four-parameter (Peleg) relationships...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28864220/evaluation-of-pulp-response-to-novel-bioactive-glass-pulp-capping-materials
#7
Yunzi Long, Siyi Liu, Lin Zhu, Qiming Liang, Xiaofeng Chen, Yanmei Dong
INTRODUCTION: This study aimed to investigate dental pulp responses to novel bioactive glass (BG) pulp capping materials after direct pulp capping in vivo. METHODS: Novel BG pulp capping materials are composed of powder and fluid. The powder is BG (82.36% SiO2, 15.36% CaO, and 2.28% P2O5), and the fluid is provided in 2 kinds: (1) phosphate buffer solution (BG-PB) and (2) phosphate buffer solution with the addition of 1 wt% sodium alginate (BG-PB-SA). After mixing the powder and fluid, BG-PB and BG-PB-SA were prepared...
August 29, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28857546/antibacterial-and-bioactive-coatings-based-on-rf-co-sputtering-of-silver-nanocluster-silica-coatings-on-peek-bioactive-glass-layers-obtained-by-electrophoretic-deposition
#8
Muhammad Atiq Ur Rehman, Sara Ferraris, Wolfgang Goldmann, Sergio Perero, Fatih Erdem Bastan, Qaisar Nawaz, G Gautier di Confiengo, Monica Ferraris, Aldo R Boccaccini
Bioactive and antibacterial coatings on stainless steel substrates were developed and characterized in this study. Silver nanocluster-silica composite coatings of 60-150 nm thickness were deposited using radio frequency (RF) co-sputtering on PEEK/bioactive glass (BG) layers (of 80-90 µm thickness) which had been electrophoretically deposited onto stainless steel. Two sputtering conditions were used by varying the deposition time (15 min and 40 min); the resulting microstructure, composition, adhesion strength, in-vitro bioactivity and antibacterial activity were investigated...
August 31, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28853299/the-osteoimmunomodulatory-properties-of-mbg-scaffold-coated-with-amino-functional-groups
#9
Deliang Zeng, Xingdi Zhang, Xiao Wang, Qingfeng Huang, Jin Wen, Xinchao Miao, Lingjie Peng, Yongsheng Li, Xinquan Jiang
Mesoporous bioactive glass (MBG) is a good scaffold for bone regeneration. In this study, amino functionalized MBG (N-MBG) was used as a model scaffold to examine the effect of the scaffold to bone marrow stromal cells (BMSCs) and macrophages. The MTT results revealed that the proliferation of BMSCs from ovariectomized rabbits was enhanced by N-MBG. Compared to the control group, the expression of osteogenic genes was significantly enhanced by N-MBG, which was related to CaSR pathway. Meanwhile, the anti-inflammatory cytokines (interleukin-10 and arginase-1) were also upregulated by N-MBG stimulation compared with MBG...
August 30, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28852357/influence-of-45s5-bioactive-glass-in-a-standard-calcium-phosphate-collagen-bone-graft-substitute-on-the-posterolateral-fusion-of-rabbit-spine
#10
Andrew J Pugely, Emily B Petersen, Nicole DeVries-Watson, Douglas C Fredericks
INTRODUCTION: Spinal fusion surgery is an effective but costly treatment for select spinal pathology. Historically iliac crest bone graft (ICBG) has remained the gold standard for achieving successful arthrodesis. Given well-established morbidity autograft harvest, multiple bone graft replacements, void fillers, and extenders have been developed. The objective of this study was to evaluate the in vivo efficacy and safety of two mineralized collagen bone void filler materials similar in composition...
2017: Iowa Orthopaedic Journal
https://www.readbyqxmd.com/read/28851519/bioactive-glass-ceramic-nanoparticles-coated-poly-l-lactic-acid-scaffold-improved-osteogenic-differentiation-of-adipose-stem-cells-in-equine
#11
Fatemeh Sadat Mahdavi, Abdolreza Salehi, Ehsan Seyedjafari, Abdollah Mohammadi-Sangcheshmeh, Abdolreza Ardeshirylajimi
Horses with big bone fractures have low chance to live mainly due to the lake of a proper treatment strategy. We believe that further attempts in equine bone tissue engineering will probably be required to meet all the needs for the lesion therapies. Therefore in this study we aimed to investigate the osteogenic differentiation capacity of equine adipose-derived stem cells (e-ASCs) on nano-bioactive glass (nBGs) coated poly(l-lactic acid) (PLLA) nanofibers scaffold (nBG-PLLA). Using electrospinning technique, PLLA scaffold was prepared successfully and coated with nBGs...
July 20, 2017: Tissue & Cell
https://www.readbyqxmd.com/read/28844964/regenerating-bone-with-bioactive-glass-scaffolds-a-review-of-in-vivo-studies-in-bone-defect-models
#12
REVIEW
Aiah A El-Rashidy, Judith A Roether, Leila Harhaus, Ulrich Kneser, Aldo R Boccaccini
Large bone defects resulting from fractures and disease are a medical concern, being often unable to heal spontaneously by the body's repair mechanisms. Bone tissue engineering (BTE) is a promising approach for treating bone defects through providing a template to guide osseous regeneration. 3D scaffolds with microstructure mimicking host bone are necessary in common BTE strategies. Bioactive glasses (BGs) attract researchers' attention as BTE scaffolds as they are osteoconductive and osteoinductive in certain formulations...
August 24, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28839410/effect-of-desensitization-using-bioactive-glass-hydroxyapatite-and-diode-laser-on-the-shear-bond-strength-of-resin-composites-measured-at-different-time-intervals-an-in-vitro-study
#13
Timsi Gupta, Shruthi Nagaraja, Sylvia Mathew, Indiresha H Narayana, K S Madhu, K Dinesh
BACKGROUND: Dentin desensitizers may change the properties of smear layer and have adverse effects on the bonding performance of adhesive systems. AIM: The aim of this study was to compare the effect of bioactive glass (BG), hydroxyapatite, and diode laser desensitization on shear bond strength of resin composites to dentin at different time intervals. MATERIALS AND METHODS: Seventy-two caries-free maxillary premolars were selected. Buccal surfaces were flattened to expose dentin...
April 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/28836753/potency-and-cytotoxicity-of-a-novel-gallium-containing-mesoporous-bioactive-glass-chitosan-composite-scaffold-as-hemostatic-agents
#14
Sara Pourshahrestani, Ehsan Zeimaran, Nahrizul Adib Kadri, Nicola Gargiulo, Hassan Mahmood Jindal, Sangeetha Vasudevaraj Naveen, Shamala Devi Sekaran, Tunku Kamarul, Mark R Towler
Chitosan-based hemostats are promising candidates for immediate hemorrhage control. However, they have some disadvantages and require further improvement to achieve the desired hemostatic efficiency. Here, a series of 1% Ga2O3-containing mesoporous bioactive glass-chitosan composite scaffolds (Ga-MBG/CHT) were constructed by the lyophilization process and the effect of various concentrations of Ga-MBG (10, 30, and 50 wt %) on the hemostatic function of the CHT scaffold was assessed as compared to that of Celox Rapid gauze (CXR), a current commercially available chitosan-coated hemostatic gauze...
September 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28832341/cu-releasing-bg-pcl-coating-on-mg-with-antibacterial-and-anticorrosive-properties-for-bone-tissue-engineering
#15
Yuyun Yang, Kai Zheng, Ruifang Liang, Astrid Mainka, Nicola Taccardi, Judith A Roether, Rainer Detsch, Wolfgang Goldmann, Sannakaisa Virtanen, Aldo R Boccaccini
Copper (Cu)-containing bioactive glass nanoparticles (Cu-BGNs) were introduced in polycaprolactone (PCL) coating systems to improve the bioactivity, antibacterial property, and corrosion resistance of vulnerable magnesium matrices under physiological conditions. The influence of different amounts of Cu-BGNs in PCL coatings was thoroughly investigated determining the wettability, electrochemical properties, and antibacterial effects against Staphylococcus carnosus and Escherichia coli, as well as their cyto-compatibility...
August 23, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28816293/-effects-of-bioactive-glass-on-reducing-the-hypersensitivity-after-full-crown-preparation
#16
H Li, Y H Liu, Z Q Luo
OBJECTIVE: To evaluate the efficacy of the 45S5 bioactive glass on the reduction of hypersensitivity of teeth prepared for full coverage crowns. METHODS: In the study, 31 prepared abutment teeth with vital pulp from 18 patients satisfied the inclusion criteria and exclusion criteria. The patients were informed consent and recruited into the study. This was a before and after self-control, single blind clinical trial. The severity of tooth hypersensitivity at baseline was evaluated, after application of the placebo, which was the powder of zinc oxide, and after application of the 45S5 bioactive glass on the same tooth...
August 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28807880/-broad-spectrum-bactericidal-activity-of-a-new-bioactive-grafting-material-f18-against-clinically-important-bacterial-strains
#17
M T Souza, L A Campanini, C R Chinaglia, O Peitl, E D Zanotto, C W O Souza
Infection is the most relevant surgical complication in implant or grafting procedures. Osteomyelitis and other chronic conditions pose a constant challenge in the current practice of medicine. In this context, a grafting biomaterial that possesses antibacterial properties combined with bioactivity could have great clinical impact. Researchers at the Vitreous Materials Laboratory (LaMaV-UFSCar) recently developed a glass composition, F18, which presents an improved workability range combined with high bioactivity...
August 11, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28799638/ftir-characterization-and-release-of-bovine-serum-albumin-from-bioactive-glasses
#18
Wai-Ching Liu, Blake Ballenger, Amnah Algarni, Mariano Velez, Tien-Min G Chu
BACKGROUND: Bioactive glass has attracted substantial interest in orthopedics, but it has been less explored as a drug carrier. This study investigated the bovine serum albumin (BSA) release from bioactive 13-93B0 and 13-93B3 glasses. METHODS: Glass disks (13-93B0 and 13-93B3; n = 5) were loaded with 4 mg of BSA and coated under different chitosan-coating conditions. The amount of BSA released in phosphate-buffered saline (PBS) was evaluated, and a degradation study was performed to find out the weight loss and pH of PBS...
August 7, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28794848/bioactive-calcium-phosphate-based-glasses-and-ceramics-and-their-biomedical-applications-a-review
#19
Md Towhidul Islam, Reda M Felfel, Ensanya A Abou Neel, David M Grant, Ifty Ahmed, Kazi M Zakir Hossain
An overview of the formation of calcium phosphate under in vitro environment on the surface of a range of bioactive materials (e.g. from silicate, borate, and phosphate glasses, glass-ceramics, bioceramics to metals) based on recent literature is presented in this review. The mechanism of bone-like calcium phosphate (i.e. hydroxyapatite) formation and the test protocols that are either already in use or currently being investigated for the evaluation of the bioactivity of biomaterials are discussed. This review also highlights the effect of chemical composition and surface charge of materials, types of medium (e...
January 2017: Journal of Tissue Engineering
https://www.readbyqxmd.com/read/28793213/critical-influence-of-cosolutes-and-surfaces-on-the-assembly-of-serpin-derived-amyloid-fibrils
#20
Michael W Risør, Dennis W Juhl, Morten Bjerring, Joachim Mathiesen, Jan J Enghild, Niels C Nielsen, Daniel E Otzen
Many proteins and peptides self-associate into highly ordered and structurally similar amyloid cross-β aggregates. This fibrillation is critically dependent on properties of the protein and the surrounding environment that alter kinetic and thermodynamic equilibria. Here, we report on dominating surface and solution effects on the fibrillogenic behavior and amyloid assembly of the C-36 peptide, a circulating bioactive peptide from the α1-antitrypsin serine protease inhibitor. C-36 converts from an unstructured peptide to mature amyloid twisted-ribbon fibrils over a few hours when incubated on polystyrene plates under physiological conditions through a pathway dominated by surface-enhanced nucleation...
August 8, 2017: Biophysical Journal
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