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Su-Hee Cho, Won-Il Jo, Ye-Eun Jo, Ku Hyun Yang, Jung Cheol Park, Deok Hee Lee
PURPOSE: To better understand the performance of four commercially available neurovascular stents in intracranial aneurysm embolization, the stents were compared in terms of their basic morphological and mechanical properties. MATERIALS AND METHODS: Four different types of stents that are currently being used for cerebral aneurysm embolization were prepared (two stents per type). Two were laser-cut stents (Neuroform and Enterprise) and two were braided from a single nitinol wire (LEO and LVIS stents)...
March 2017: Neurointervention
Ligen Shi, Mading Zhou, Shenbin Xu, Qun Wu, Wei Yan, Jianmin Zhang
Intracavernous internal carotid artery (ICICA) aneurysm secondary to pituitary infection is exceedingly rare. We report an unusual case of a 63-year-old man who presented with acute left blepharoptosis and imaging findings of a pituitary infection. Interestingly, sudden onset of right blepharoptosis occurred after anti-infective therapy for ten days. Digital subtraction angiography revealed a right ICICA aneurysm. After six months of follow-up visits, enlargement of the ICICA aneurysm was observed, and the endovascular technique of a low-profile visualized intraluminal support (LVIS) stent combined with five detachable coils was successfully performed to treat the ICICA aneurysm with preservation of the internal carotid artery...
February 23, 2017: World Neurosurgery
Jian Liu, Yisen Zhang, Yang Wang, Shiqing Mu, Xinjian Yang
BACKGROUND: Ruptured intracranial fusiform aneurysms involving small-diameter parent arteries are difficult to treat. Parent artery occlusion is a relatively simple and reliable treatment. However, occasionally, the parent arteries have to be retained. The arrival of the low-profile stent (LVIS Jr.) has made reconstructive endovascular treatment for fusiform aneurysms involving small-diameter parent arteries possible. CASE DESCRIPTION: This report describes an innovative method for stent-assisted coiling (stenting after coiling technique using only 1 microcatheter) and describes our initial experience and feasibility of this technique...
March 2017: World Neurosurgery
J A Grossberg, R A Hanel, G Dabus, K Keigher, D C Haussen, E Sauvageau, I Linfante, D Gonsales, P Aguilar Salinas, M Bouslama, M Mayich, R G Nogueira, D K Lopes
BACKGROUND: The Low-profile Visualized Intraluminal Support (LVIS) Junior stent is newly approved for the treatment of wide-necked intracranial aneurysms. OBJECTIVE: To report our multicenter experience with use of the LVIS Jr device. METHODS: The neurointerventional databases of the participating institutions were retrospectively reviewed for aneurysms treated with LVIS Jr from the time of Food and Drug Administration approval until February 2016...
October 27, 2016: Journal of Neurointerventional Surgery
Yoshiyasu Kitagawa, Dai Ikebe, Taro Hara, Kazuki Kato, Teisuke Komatsu, Fukuo Kondo, Ryousaku Azemoto, Fumitake Komoda, Taketsugu Tanaka, Hirofumi Saito, Makiko Itami, Taketo Yamaguchi, Takuto Suzuki
Rectal neuroendocrine tumor (RNET) lymphovascular invasion (LVI) is regarded as an important predictor of nodal metastasis after endoscopic resection (ER). However, little is known about the frequency of immunohistochemical detection of LVI in RNETs. This study was performed to establish the actual detection of LVI rate in RNETs ≤10 mm and to evaluate associated clinical outcomes. We retrospectively reviewed the records for 98 consecutive patients treated by ER with a total of 102 RNETs ≤10 mm. Tissue sections were labeled with hematoxylin-eosin (HE) stain, the D2-40 monoclonal antibody to evaluate lymphatic invasion, and Elastica van Gieson (EVG) stain to detect venous invasion...
November 2016: Cancer Medicine
Ronak Dholakia, Chander Sadasivan, David J Fiorella, Henry H Woo, Baruch B Lieber
Cerebral aneurysms are pathological focal evaginations of the arterial wall at and around the junctions of the circle of Willis. Their tenuous walls predispose aneurysms to leak or rupture leading to hemorrhagic strokes with high morbidity and mortality rates. The endovascular treatment of cerebral aneurysms currently includes the implantation of fine-mesh stents, called flow diverters, within the parent artery bearing the aneurysm. By mitigating flow velocities within the aneurysmal sac, the devices preferentially induce thrombus formation in the aneurysm within hours to days...
February 1, 2017: Journal of Biomechanical Engineering
Mingming Zhang, Yian Ouyang, Hao Huang, Yugang Jiang, Mengqiang Yu
OBJECTIVE: To investigate the safety and short-term efficacy of stent on 17 patients with very small intracranial aneurysms.
 METHODS: A total of 17 patients with very small intracranial aneurysms were treated by LVIS stent from October 2014 to November 2015. The location, size of the aneurysms and the branch around aneurysms were evaluated by digital subtraction angiography (DSA). The metal coverage for aneurysms was enhanced by using deployment technology ("compression" mode)...
August 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
Jai Jai Shiva Shankar, Aiman Quateen, Alain Weill, Donatella Tampieri, Maria Del Pilar Cortes, Robert Fahed, Satya Patro, Zul Kaderali, Cheemun Lum, Howard Lesiuk, Uzair Ahmed, Lissa Peeling, Michael E Kelly, Daniela Iancu
INTRODUCTION: Stents reduce the rate of angiographic recurrence of intracranial aneurysms. The newest stent for intracranial use is the Low-profile Visible Intraluminal Support device (LVIS Jr). OBJECTIVE: To assess the efficacy of the new stent in a multicenter retrospective registry. MATERIALS AND METHOD: Centers across Canada using LVIS Jr were contacted and asked to participate in a retrospective registry of consecutive patients treated with LVIS Jr for intracranial aneurysms between January 2013 and July 2015...
August 19, 2016: Journal of Neurointerventional Surgery
Chao Wang, Zhongbin Tian, Jian Liu, Linkai Jing, Nikhil Paliwal, Shengzhang Wang, Ying Zhang, Jianping Xiang, Adnan H Siddiqui, Hui Meng, Xinjian Yang
BACKGROUND: The aim of this study was to quantify the effect of the new Low-profile Visualized Intraluminal Support (LVIS®D) device and the difference of fluid diverting effect compared with the Pipeline device and the Enterprise stent using computational fluid dynamics (CFD). METHODS: In this research, we simulated three aneurysms constructed from 3D digital subtraction angiography (DSA). The Enterprise, LVIS and the Pipeline device were virtually conformed to fit into the vessel lumen and placed across the aneurysm orifice...
July 2, 2016: Journal of Translational Medicine
Jessica G Shih, Shahriar Shahrokhi, Marc G Jeschke
The aims of this article are to review low-voltage vs high-voltage electrical burn complications in adults and to identify novel areas that are not recognized to improve outcomes. An extensive literature search on electrical burn injuries was performed using OVID MEDLINE, PubMed, and EMBASE databases from 1946 to 2015. Studies relating to outcomes of electrical injury in the adult population (≥18 years of age) were included in the study. Forty-one single-institution publications with a total of 5485 electrical injury patients were identified and included in the present study...
January 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
Xiaoguang Zhang, Junjie Zhong, Heng Gao, Feng Xu, Nicholas C Bambakidis
OBJECTIVE: Despite promising initial results, current knowledge regarding the use of the Low-profile Visualized Intraluminal Support (LVIS) device to treat wide-necked intracranial aneurysms is still limited. Our aim is to evaluate the feasibility, efficacy, and safety of the LVIS device in stent-assisted coiling of intracranial aneurysms. METHODS: We conducted a systematic review by searching PubMed, EMBASE, and Cochrane Library for all published studies on the treatment of intracranial aneurysms with the LVIS device up to March 2016...
May 20, 2016: Journal of Neurointerventional Surgery
Huijian Ge, Xianli Lv, Xinjian Yang, Hongwei He, Hengwei Jin, Youxiang Li
OBJECTIVE: This retrospective study compared clinical and angiographic outcomes between LVIS and Enterprise stents. MATERIALS AND METHODS: From November 2014 to December 2015, total 190 patients with 208 unruptured intracranial aneurysms were coiled assisted by LVIS and Enterprise stents. Procedure-related complications, clinical outcomes, and angiographic results were analyzed retrospectively. RESULTS: A total of 92 patients with 96 aneurysms received LVIS stents and 98 patients with 112 aneurysms were treated with Enterprise stents...
July 2016: World Neurosurgery
Faisal Alghamdi, Benjamin Mine, Ricardo Morais, Pietro Scillia, Boris Lubicz
INTRODUCTION: The Low-profile Visualized Intraluminal Support (LVIS) Junior stent is dedicated for endovascular treatment of wide-neck intracranial aneurysms located on small-diameter vessels (2-3.5 mm). This study reports midterm clinical and anatomical results of this device. METHODS: This study was approved by authors' ethical committees. A retrospective review of our prospectively maintained database identified all patients treated by this stent in three institutions...
July 2016: Neuroradiology
Elizabeth Hai Yen Du, Jai Jai Shiva Shankar
Wide-necked bifurcation intracranial aneurysms have traditionally not been amenable to coil embolization with the use of a single stent due to the high risk of coil prolapse. Y-configuration double stent-assisted coil embolization ('Y-stenting') of this aneurysm type has been shown to have generally good clinical outcomes, although the technique is complex with various challenges described in the literature. The compliant and flexible closed-cell design of braided stents such as the LVIS Jr allows for the creation of a 'shelf' across the aneurysm neck sufficient to prevent coil prolapse...
February 4, 2016: Journal of Neurointerventional Surgery
Zhengzhe Feng, Yibin Fang, Yi Xu, Bo Hong, Wenyuan Zhao, Jianmin Liu, Qinghai Huang
BACKGROUND: The low profile visualized intraluminal support (LVIS) device is a new generation of self-expanding braided stents recently introduced into China for stent assisted coiling of intracranial aneurysms. This study assessed the clinical safety and efficacy of the LVIS stent for embolization of intracranial saccular aneurysms. METHODS: Patients with intracranial saccular aneurysms treated using the LVIS device in our center between April 2014 and December 2014 were reviewed...
November 2016: Journal of Neurointerventional Surgery
Edgar A Samaniego, German Abdo, Ricardo A Hanel, Andrey Lima, Santiago Ortega-Gutierrez, Guilherme Dabus
OBJECTIVE: To describe the treatment of posterior inferior cerebellar artery (PICA) aneurysms with the Low-profile Visualized Intraluminal Support Device (LVIS Jr) stent. MATERIALS AND METHODS: The databases of three institutions were retrospectively reviewed. Patients who underwent endovascular treatment of PICA aneurysms using a reconstructive technique where the LVIS Jr stent was totally or partially deployed into the PICA were included in the analysis. Clinical presentation, aneurysm and PICA sizes, procedural complications, and clinical and angiographic follow-up information was recorded and analyzed...
October 2016: Journal of Neurointerventional Surgery
David Fiorella, Adam Arthur, Alan Boulos, Orlando Diaz, Pascal Jabbour, Lee Pride, Aquilla S Turk, Henry H Woo, Colin Derdeyn, John Millar, Andrew Clifton
INTRODUCTION: The low-profile visualized intraluminal support (LVIS) device is a new, braided, intracranial microstent designed for stent-assisted coiling. OBJECTIVE: To present the results of a single-arm, prospective, multicenter trial of the LVIS for treatment of wide-necked intracranial aneurysms. METHODS: 31 patients with unruptured, wide-necked (neck ≥4 mm or dome:neck ratio ≤2) intracranial aneurysms were treated with the LVIS device and bare platinum coils at six US centers (investigational device exemption G110014)...
September 2016: Journal of Neurointerventional Surgery
Robert J Darflinger, Kuo Chao
The treatment of wide-neck bifurcation cerebral aneurysms is challenging especially if at least one of the arteries arise from an obtuse angle. These wide-neck bifurcation aneurysms are difficult to treat with the usual balloon and stent assisted coiling, including Y stenting or double-barrel stent techniques [1, 2]. Other available options include using current devices with the waffle cone or double waffle cone techniques [3, 4]. Novel devices that are in development include intrasaccular devices and the barrel bifurcation vascular reconstruction device (Covidien) [5, 6, 7]...
July 2015: Journal of Vascular and Interventional Neurology
Matías Negrotto, Roberto Crosa, Walter Casagrande
BACKGROUND AND PURPOSE: Endovascular treatment of broad-neck, complex cerebral aneurysms is a challenging issue. Placement of a stent over the aneurysm neck and secondary coil embolization prevents coil migration and allows dense packing of the coils. Another challenge is represented by distal aneurysms situated in small vessels. In these cases, the use of little stents, which we are going call ministents, could be a good decision. These low-profile intracranial ministents can be deployed into arteries with diameters between 1...
October 2015: Interventional Neuroradiology
Zhengzhe Feng, Lei Zhang, Qiang Li, Rui Zhao, Yi Xu, Bo Hong, Wenyuan Zhao, Jianmin Liu, Qinghai Huang
We performed this retrospective study to assess the clinical safety and efficacy of the low-profile visualized intraluminal support junior (LVIS Jr.; MicroVention, Aliso Viejo, CA, USA) stent placement in anterior communicating artery (ACA) aneurysms. ACA aneurysms are some of the most common intracranial aneurysms. Stent placement is particularly difficult due to the complexity of the vascular anatomy and the small vessels of the ACA complex. From November 2013 and June 2014, LVIS Jr. stent-assisted coiling was performed in 11 patients with 12 wide-neck ACA aneurysms...
August 2015: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
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