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https://www.readbyqxmd.com/read/28237685/evaluation-of-a-new-handheld-point-of-care-blood-gas-analyser-using-100-equine-blood-samples
#1
David Bardell, Eleanor West, J Mark Senior
OBJECTIVES: To determine whether the Enterprise point-of-care blood analysis system (EPOC) produces results in agreement with two other blood gas analysers in regular clinical use (i-STAT and Radiometer ABL77) and to investigate the precision of the new machine when used with equine whole blood. STUDY DESIGN: Prospective, randomized, non-blinded, comparative laboratory analyser study. ANIMALS: Horses admitted to a university teaching hospital requiring arterial or venous blood gas analysis as part of their routine clinical management...
February 22, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28231148/potential-use-of-gamma-irradiated-ethnic-ready-to-eat-foods-to-improve-the-nutritional-status-of-landslide-victims
#2
REVIEW
Zubaidah Irawati Koenari, Carmen M Siagian, Bona Simanungkalit, Asti Nilatany, Indra Mustika Pratama, Deudeu Lasmawati, Cecep M Nurcahya
The safety and high quality of ethnic ready-to-eat foods as a source of nourishment and food supplies chain to the remote areas become particularly important. Consuming healthy and balanced nutritional foods means eating better quality foods in proper quantities. Such foods can be developed through a preservation technique by using ionizing radiation. Although implementation of the technology for certain foodstuffs has been implemented in some countries, application of the process to a complete set of meals for selected target groups is still very limited...
July 26, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28229306/behavioral-and-social-sciences-at-the-national-institutes-of-health-adoption-of-research-findings-in-health-research-and-practice-as-a-scientific-priority
#3
William T Riley
The National Institutes of Health's Office of Behavioral and Social Sciences Research (OBSSR) recently released its Strategic Plan for 2017 to 2021. This plan highlights three scientific priorities: (1) improve the synergy of basic and applied behavioral and social sciences research, (2) enhance and promote the research infrastructure, methods, and measures needed to support a more cumulative and integrated approach to behavioral and social sciences research, and (3) facilitate the adoption of behavioral and social sciences research findings in health research and in practice...
February 22, 2017: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/28229132/representing-documents-via-latent-keyphrase-inference
#4
Jialu Liu, Xiang Ren, Jingbo Shang, Taylor Cassidy, Clare R Voss, Jiawei Han
Many text mining approaches adopt bag-of-words or n-grams models to represent documents. Looking beyond just the words, i.e., the explicit surface forms, in a document can improve a computer's understanding of text. Being aware of this, researchers have proposed concept-based models that rely on a human-curated knowledge base to incorporate other related concepts in the document representation. But these methods are not desirable when applied to vertical domains (e.g., literature, enterprise, etc.) due to low coverage of in-domain concepts in the general knowledge base and interference from out-of-domain concepts...
April 2016: Proceedings of the International World-Wide Web Conference
https://www.readbyqxmd.com/read/28226421/opening-plenary-speaker-human-genomics-precision-medicine-and-advancing-human-health
#5
Eric D Green
Starting with the launch of the Human Genome Project in 1990, the past quarter-century has brought spectacular achievements in genomics that dramatically empower the study of human biology and disease. The human genomics enterprise is now in the midst of an important transition, as the growing foundation of genomic knowledge is being used by researchers and clinicians to tackle increasingly complex problems in biomedicine. Of particular prominence is the use of revolutionary new DNA sequencing technologies for generating prodigious amounts of DNA sequence data to elucidate the complexities of genome structure, function, and evolution, as well as to unravel the genomic bases of rare and common diseases...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28214991/efficiency-analysis-of-an-interoperable-healthcare-operations-platform
#6
Thomas F Osborne, Reese H Clark, Jason Blackowiak, Patrick J Williamson, Shannon M Werb, Benjamin W Strong
(1) Develop an enterprise platform to unify isolated information, software applications and team members. (2) Assess the efficiency of one benefit of the platform through comparative testing of employee document retrieval times. (3) Evaluate the level of satisfaction among our target audience. We developed an infrastructure to integrate information throughout our practice and make it available on a unified, secure, and remotely accessible platform. We solicited our practice for volunteers to test the new system...
April 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28207982/understanding-ethical-issues-of-research-participation-from-the-perspective-of-participating-children-and-adolescents-a-systematic-review
#7
Stacey Crane, Marion E Broome
BACKGROUND: The past 20 years have seen distinct shifts in the way the participation of children and adolescents in research is viewed. This has been emphasized by the growing pediatric research enterprise. Additional information on children's and adolescents' experiences during research participation is needed to better inform researchers on the ethical conduct of research with this vulnerable population. AIMS: The objective of this analysis was to examine ethical issues in research with children and adolescents from their perspective as participants, including: assent, parental consent, risk perception, impact of research participation, and incentives...
February 16, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28204942/molecular-modeling-in-the-age-of-clinical-genomics-the-enterprise-of-the-next-generation
#8
Jeremy W Prokop, Jozef Lazar, Gabrielle Crapitto, D Casey Smith, Elizabeth A Worthey, Howard J Jacob
Protein modeling and molecular dynamics hold a unique toolset to aide in the characterization of clinical variants that may result in disease. Not only do these techniques offer the ability to study under characterized proteins, but they do this with the speed that is needed for time-sensitive clinical cases. In this paper we retrospectively study a clinical variant in the XIAP protein, C203Y, while addressing additional variants seen in patients with similar gastrointestinal phenotypes as the C203Y mutation...
March 2017: Journal of Molecular Modeling
https://www.readbyqxmd.com/read/28198923/new-races-new-diseases-the-possibility-of-colonization-through-racial-mixing-in-history-of-brazil-1810-1819-by-robert-southey
#9
Flávia Florentino Varella
The possibility that the climate altered the temperament of people who were not native to a given region was a widely held belief even before the discovery of the Americas. Changes in air, temperature, and diet were believed to contribute decisively to whether races degenerated or flourished. In the New World, the black, European, and indigenous races mixed, reconfiguring European diseases. I explore how historian Robert Southey viewed this mixture of races in a positive light, especially the mixture of indigenous and Portuguese blood, resulting in the mameluco...
December 2016: História, Ciências, Saúde—Manguinhos
https://www.readbyqxmd.com/read/28193464/igas-a-framework-for-using-electronic-intraoperative-medical-records-for-genomic-discovery
#10
Matthew A Levin, Thomas T Joseph, Janina M Jeff, Rajiv Nadukuru, Stephen B Ellis, Erwin P Bottinger, Eimear E Kenny
OBJECTIVE: Design and implement a HIPAA and Integrating the Healthcare Enterprise (IHE) profile compliant automated pipeline, the integrated Genomics Anesthesia System (iGAS), linking genomic data from the Mount Sinai Health System (MSHS) BioMe biobank to electronic anesthesia records, including physiological data collected during the perioperative period. The resulting repository of multi-dimensional data can be used for precision medicine analysis of physiological readouts, acute medical conditions, and adverse events that can occur during surgery...
February 10, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28193378/image-sharing-in-radiology-a-primer
#11
REVIEW
Arindam R Chatterjee, Seth Stalcup, Arjun Sharma, T Shawn Sato, Pushpender Gupta, Yueh Z Lee, Christopher Malone, Morgan McBee, Elise L Hotaling, Akash P Kansagra
By virtue of its information technology-oriented infrastructure, the specialty of radiology is uniquely positioned to be at the forefront of efforts to promote data sharing across the healthcare enterprise, including particularly image sharing. The potential benefits of image sharing for clinical, research, and educational applications in radiology are immense. In this work, our group-the Association of University Radiologists (AUR) Radiology Research Alliance Task Force on Image Sharing-reviews the benefits of implementing image sharing capability, introduces current image sharing platforms and details their unique requirements, and presents emerging platforms that may see greater adoption in the future...
March 2017: Academic Radiology
https://www.readbyqxmd.com/read/28193170/generating-evidence-on-a-risk-based-monitoring-approach-in-the-academic-setting-lessons-learned
#12
Belinda von Niederhäusern, Annette Orleth, Sabine Schädelin, Nawal Rawi, Martin Velkopolszky, Claudia Becherer, Pascal Benkert, Priya Satalkar, Matthias Briel, Christiane Pauli-Magnus
BACKGROUND: In spite of efforts to employ risk-based strategies to increase monitoring efficiency in the academic setting, empirical evidence on their effectiveness remains sparse. This mixed-methods study aimed to evaluate the risk-based on-site monitoring approach currently followed at our academic institution. METHODS: We selected all studies monitored by the Clinical Trial Unit (CTU) according to Risk ADApted MONitoring (ADAMON) at the University Hospital Basel, Switzerland, between 01...
February 14, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28191910/the-rhetorical-use-of-random-sampling-crafting-and-communicating-the-public-image-of-polls-as-a-science-1935-1948
#13
Dominic Lusinchi
The scientific pollsters (Archibald Crossley, George H. Gallup, and Elmo Roper) emerged onto the American news media scene in 1935. Much of what they did in the following years (1935-1948) was to promote both the political and scientific legitimacy of their enterprise. They sought to be recognized as the sole legitimate producers of public opinion. In this essay I examine the, mostly overlooked, rhetorical work deployed by the pollsters to publicize the scientific credentials of their polling activities, and the central role the concept of sampling has had in that pursuit...
February 13, 2017: Journal of the History of the Behavioral Sciences
https://www.readbyqxmd.com/read/28186049/an-enterprise-architecture-perspective-to-electronic-health-record-based-care-governance
#14
Bogdan Motoc
This paper proposes an Enterprise Architecture viewpoint of Electronic Health Record (EHR) based care governance. The improvements expected are derived from the collaboration framework and the clinical health model proposed as foundation for the concept of EHR.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28182823/how-to-direct-the-neuronal-growth-process-in-peripheral-nerve-regeneration-future-strategies-for-nanosurfaces-scaffold-and-magnetic-nanoparticles
#15
Andrea Poggetti, Pietro Battistini, Paolo Domenico Parchi, Michela Novelli, Simona Raffa, Marco Cecchini, Anna Maria Nucci, Michele Lisanti
Currently, the gold standard to repair large nerve defects is the autologous nerve graft. These solutions offer a mechanical support, adhesion substrates, and, with Schwann cells (SC), a source of neurotropic factors for axonal growth. The technical limits are the donor side damage, multiple surgical accesses, and the unavailability of large amounts of grafts. In recent years, several researchers focused their attention on the interaction between cells (nervous and glial) and physic-chemical cues that arise from the extracellular milieu...
February 7, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28167709/tracking-the-changing-landscape-of-corporate-wellness-companies
#16
Jean Abraham, Katie M White
The corporate wellness industry is diversifying and now includes legacy wellness companies, divisions of health plans or delivery systems, and new technology-focused solution enterprises. We conducted in-depth interviews with leaders in the industry to understand the changes in its supply side, the drivers of these changes, future trends, and their implications for employers and policy makers. Three key trends emerged from the interviews: The industry is expanding and becoming increasingly diverse and competitive; wellness companies are redefining their business models to promote a culture of health; and the value proposition of employee wellness programs is shifting from a return on investment to a new idea: value on investment...
February 1, 2017: Health Affairs
https://www.readbyqxmd.com/read/28167632/priority-prediction-and-the-ethical-research-enterprise
#17
Spencer Phillips Hey
No abstract text is available yet for this article.
February 6, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28167340/knowledge-and-power-in-policy-making-for-child-survival-in-niger
#18
Sarah L Dalglish, Daniela C Rodríguez, Abdoutan Harouna, Pamela J Surkan
Calls to enhance the use of scientific evidence in international health and development policy have increased in recent years; however, analytic frameworks for understanding evidence use focus on narrowly scientific research and were created using data and observations nearly exclusively from Western countries. We examine processes of health policy development in a case study of Niger, a low-income West African country that adopted integrated community case management of childhood illness (iCCM) beginning in 2007, resulting in measurable declines in child mortality...
January 30, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28157766/effect-of-interaction-between-noise-and-a1166c-site-of-at1r-gene-polymorphism-on-essential-hypertension-in-an-iron-and-steel-enterprise-workers
#19
Junwang Tong, Ying Wang, Juxiang Yuan, Jingbo Yang, Zhaoyang Wang, Yao Zheng, Feng Chai, Xiangwen Li
OBJECTIVE: This study aimed to analyze the interaction of Angiotensin II type 1 receptor (AT1R) gene polymorphism and occupational noise on the occurrence of essential hypertension (EH) in steel and iron enterprise men workers. METHODS: A case control study of 935 iron and steel enterprise men workers was conducted, which included 312 cases of hypertension and 623 cases without hypertension. The noise at the workplace was assessed. Polymorphism of AT1R of the workers was examined using polymerase chain reaction - restriction fragment length polymorphism...
February 2, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28155680/phantom-based-experimental-validation-of-fast-virtual-deployment-of-self-expandable-stents-for-cerebral-aneurysms
#20
Qianqian Zhang, Zhuangyuan Meng, Ying Zhang, Kai Yao, Jian Liu, Yisen Zhang, Linkai Jing, Xinjian Yang, Nikhil Paliwal, Hui Meng, Shengzhang Wang
BACKGROUND: Endovascular intervention using a stent is a mainstream treatment for cerebral aneurysms. To assess the effect of intervention strategies on aneurysm hemodynamics, we have developed a fast virtual stenting (FVS) technique to simulate stent deployment in patient-specific aneurysms. However, quantitative validation of the FVS against experimental data has not been fully addressed. In this study, we performed in vitro analysis of a patient-specific model to illustrate the realism and usability of this novel FVS technique...
December 28, 2016: Biomedical Engineering Online
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