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S E Speidel, B A Buckley, R J Boldt, R M Enns, J Lee, M L Spangler, M G Thomas
Reproductive performance is the most important component of cattle production from the standpoint of economic sustainability of commercial beef enterprises. Heifer Pregnancy (HPG) and Stayability (STAY) genetic predictions are two selection tools published by the Red Angus Association of America (RAAA) to assist with improvements in reproductive performance. Given the importance of HPG and STAY to the profitability of commercial beef enterprises, the objective of this study was to identify QTL associated with both HPG and STAY in Red Angus cattle...
February 19, 2018: Journal of Animal Science
Allison Larg, John R Moss, Nicola Spurrier
Objective Arguments to fund obesity prevention have often focused on the growing hospital costs of associated diseases. However, the relative contribution of overweight and obesity to public hospital expenditure growth is not well understood. This paper examines the effect of overweight and obesity on acute public hospital in-patient expenditure in South Australia over time compared with other expenditure drivers. Methods Annual inflation-adjusted acute public admitted expenditure attributable to a high body mass index was estimated for 2007-08 and 2011-12 and compared with other expenditure drivers...
February 22, 2018: Australian Health Review: a Publication of the Australian Hospital Association
Junwei Zheng, Guangdong Wu
Projects are characterized by long working hours, complex tasks and being a kind of temporary organization. As such, work-family conflict is particularly prominent for project employees. This research examined whether and how work-family conflict affects professional commitment among Chinese project professionals. Research hypotheses were developed to explore the relationship between work-family conflict, professional commitment to the project and the mediating effects of perceived organizational support. Data were collected from 327 project managers or professionals working in construction enterprises in China; data were analyzed using structural equation modeling, applying the bootstrapping method...
February 15, 2018: International Journal of Environmental Research and Public Health
Alena Fröhlichová, Jiřina Száková, Jana Najmanová, Pavel Tlustoš
Central Bohemia (Czech Republic) has highly developed industry and a dense rail network. Here, we aimed to determine the content of risk elements in dandelion plants (Taraxacum sect. Ruderalia) growing near train stations, industrial enterprises, and in the city parks of 16 cities in the Central Bohemian region. The highest element contents in the soils were found in industrial areas affected by the historical mining and smelting activities; contemporary industry showed no substantial effect on the soil element contents...
February 19, 2018: Environmental Monitoring and Assessment
George Rugare Chingarande, Keymanthri Moodley
BACKGROUND: Compensation for research related injuries is a subject that is increasingly gaining traction in developing countries which are burgeoning destinations of multi center research. However, the existence of disparate compensation rules violates the ethical principle of fairness. The current paper presents a comparison of the policies of Brazil, Russia, India, China and South Africa (BRICS). METHODS: A systematic search of good clinical practice guidelines was conducted employing search strategies modeled in line with the recommendations of ADPTE Collaboration (2007)...
February 17, 2018: BMC Medical Ethics
Yong Ji, Peijun Wu, Jie Zhang, Jun Zhang, Youfeng Zhou, Yongwen Peng, Shifeng Zhang, Gaotang Cai, Guiqing Gao
In this research, Ganzhou Chinese Cabbage (Brassica rapa pekinensis), Native Purple Garlic (Allium sativum L) and Leping Radish (Raphanus sativus L) widely planted and distributed along the Le'an River were chosen in the present study. Soil physical-chemical properties, nutrients contents as well as heavy metals elements accumulated in both soils and vegetables collected from 24 sites were analyzed by lab analysis combined with statistical method which was also used for calculation of contamination factor, pollution indexes and hazardous index...
February 8, 2018: Chemosphere
Amy Corneli, Zachary Hallinan, Gerrit Hamre, Brian Perry, Jennifer C Goldsack, Sara B Calvert, Annemarie Forrest
The mission of the Clinical Trials Transformation Initiative, a public-private partnership co-founded by the U.S. Food and Drug Administration and Duke University, is to develop and drive adoption of practices that will increase the quality and efficiency of clinical trials. The Clinical Trials Transformation Initiative works collaboratively with key stakeholders, implements "fit-for-purpose" evidence-gathering projects, and develops actionable recommendations and tools to address the challenges faced by the clinical trials enterprise...
February 2018: Clinical Trials: Journal of the Society for Clinical Trials
Bray Patrick-Lake
Patient engagement is an increasingly important aspect of successful clinical trials. Over the past decade, as patient group involvement in clinical trials has continued to increase and diversify, the Clinical Trials Transformation Initiative has not only recognized the crucial role patients play in improving the clinical trial enterprise but also made a deep commitment to help grow and shape the emerging field of patient engagement. This article describes the evolution of patient engagement including the origins of the patient engagement movement; barriers to successful engagement and remaining challenges to full and valuable collaboration between patient groups and trial sponsors; and Clinical Trials Transformation Initiative's role in influencing the field through organizational practices, formal project work and resulting recommendations, and external advocacy efforts...
February 2018: Clinical Trials: Journal of the Society for Clinical Trials
P Tenaerts, L Madre, M Landray
The Clinical Trials Transformation Initiative reflects on 10 years of working to improve the quality and efficiency of clinical trials. This article highlights many of the Clinical Trials Transformation Initiative's accomplishments and offers examples of the impact that the Clinical Trials Transformation Initiative has had on the clinical trials enterprise. After conducting more than 25 projects and issuing recommendations for specific strategies to improve the design and execution of clinical trials, some common themes and lessons learned have emerged...
February 2018: Clinical Trials: Journal of the Society for Clinical Trials
Bernd Neumayr, Christoph G Schuetz, Manfred A Jeusfeld, Michael Schrefl
An enterprise database contains a global, integrated, and consistent representation of a company's data. Multi-level modeling facilitates the definition and maintenance of such an integrated conceptual data model in a dynamic environment of changing data requirements of diverse applications. Multi-level models transcend the traditional separation of class and object with clabjects as the central modeling primitive, which allows for a more flexible and natural representation of many real-world use cases. In deep instantiation, the number of instantiation levels of a clabject or property is indicated by a single potency...
2018: Software and Systems Modeling
Denise J Montell
Today's political climate can seem hostile to science. Alternative facts, climate change denial, and relabeling of actual news as fake news are discouraging phenomena for sure. But these trends make it more important than ever to engage our politicians. Take heart! There is something you can do. You can show your representatives firsthand the amazing things you do, evidence of the economic engine that your activities generate, and the real people behind the discoveries. I did, and it was fun. We invited our congressman to the University of California, Santa Barbara (UCSB), and he accepted! For 2 hours, we explained and demonstrated efforts to cure blindness using stem cells, the medical implications of the discovery that cells can recover from the brink of death, a mosquito lab striving to eliminate insect-borne disease, and an Alzheimer's disease laboratory...
February 15, 2018: Molecular Biology of the Cell
Shawn G Ehlers, William E Field
This research focused on the advancements made in enabling agricultural workers with impaired mobility to access and operate off-road agricultural machinery. Though not a new concept, technological advancements in remote-controlled lifts, electronic actuators, electric over hydraulic controllers, and various modes of hand controls have advanced significantly allowing operators with limited mobility to resume a high level of productivity in agricultural-related enterprises. In the U.S., approximately 1.7% of the population is living with some form of paralysis or significant mobility impairment...
February 14, 2018: Assistive Technology: the Official Journal of RESNA
Rhea E Powell, Danica Stone, Judd E Hollander
BACKGROUND: Real-time video visits are increasingly used to provide care in a number of settings because they increase access and convenience of care, yet there are few reports of health system experiences. OBJECTIVE: The objective of this study is to report health system and patient experiences with implementation of a telehealth scheduled video visit program across a health system. METHODS: This is a mixed methods study including (1) a retrospective descriptive report of implementation of a telehealth scheduled visit program at one large urban academic-affiliated health system and (2) a survey of patients who participated in scheduled telehealth visits...
February 13, 2018: JMIR Medical Informatics
Natalie V Schwatka, Erin Shore, Adam Atherly, David Weitzenkamp, Miranda J Dally, Claire V S Brockbank, Liliana Tenney, Ron Z Goetzel, Kimberly Jinnett, James McMillen, Lee S Newman
OBJECTIVE: To examine how work and non-work health-related factors contribute to workers' compensation (WC) claims by gender. METHODS: Workers (N = 16,926) were enrolled in the Pinnacol Assurance Health Risk Management study, a multiyear, longitudinal research program assessing small and medium-sized enterprises in Colorado. Hypotheses were tested using gender stratified logistic regression models. RESULTS: For both women and men, having incurred a prior WC claim increased the odds of a future claim...
February 12, 2018: Journal of Occupational and Environmental Medicine
Patricia Eckardt, Marilyn J Hammer, Margaret Barton-Burke, Margaret McCabe, Christine T Kovner, Liza Behrens, Heather Reens, Barry S Coller
Introduction: Nurses are critical to the research enterprise. However all nurses are not prepared to participate as members of the research team since education and training in clinical research nursing and nurse-specific Good Clinical Practice are not consistently included in nursing curricula. The lack of nurse education and training in clinical research and Good Clinical Practice leaves research participants vulnerable with a nursing workforce that is not prepared to balance fidelity to protocol and patient quality care and safety...
October 2017: Journal of Clinical and Translational Science
Z L Xing, W L Yu, M Xu, C Y Yu
Objective: To investigate the infertility rate and influencing factors of female workers in China's nine industries. Methods: Using multi-stage sampling method, from January to November in 2016. A cross-sectional survey was conducted on the infertility of 33 685 female workers in the nine industries including medical and health, petrochemical, metallurgy, railway, machinery manufacturing and electronics,a questionnaire survey. First, three provincial capitals were randomly selected in seven regions. And then we consulted and communicated with the hospital of the provincial city's occupational disease prevention and treatment, marking and coding the target enterprise within its jurisdiction, In these enterprises, we randomly selected five companies...
February 6, 2018: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
Luo Liu, Xinliang Xu, Yueming Hu, Zhenjie Liu, Zhi Qiao
Rape is a non-grain feedstock with several characteristics that make it suitable for biofuel production, such as high oil yields and low environmental impact. Planting rape on winter fallow fields could allow for seasonal rotation between the bioenergy production and agricultural production. In the present study, the Global Agro-Ecological Zones model was used to estimate the production potential of rapeseed on winter fallow fields in the Yangtze River region from 2010 to 2015. Life cycle assessment was then conducted to calculate energy efficiency and greenhouse gas emissions from the entire energy-producing process and to estimate the number of bioenergy enterprises and their spatial distribution...
February 8, 2018: Science of the Total Environment
Steluta Manolache, Andreea Nita, Cristiana M Ciocanea, Viorel D Popescu, Laurentiu Rozylowicz
Successful management of complex social-ecological landscapes overlapping Natura 2000 sites requires collaboration between various actors such as law enforcement agencies, NGOs and enterprises. Natura 2000 governance is stimulated by central actors (e.g., Natura 2000 administrators), with successes and failures of management activities depending on the capacity of the network leader to implement a collaborative approach to environmental governance. By using social network analysis, we analysed the cooperation, information flow and capacity for collective action within Natura 2000 governance networks within two Romanian protected areas: Lower Siret Floodplain and Iron Gates Natural Park...
February 8, 2018: Journal of Environmental Management
Jonas Alex Morales Saute, Laura Bannach Jardim
Spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) is an autosomal dominant multiple neurological systems degenerative disorder caused by a CAG repeat expansion at ATXN3 gene. Only a few treatments were evaluated in randomized clinical trials (RCT) in SCA3/MJD patients, with a lack of evidence for both disease-modifying and symptomatic therapies. The present chapter discuss in detail major methodological issues for planning future RCT for SCA3/MJD. There are several potential therapies for SCA3/MJD with encouraging preclinical results...
2018: Advances in Experimental Medicine and Biology
P A Windsor, S Nampanya, V Putthana, K Keonam, K Johnson, R D Bush, S Khounsy
Progressing economic development in Southeast Asia has increased regional demand for goat meat, leading to expanding production by smallholders and recently, development of commercial farms. In Laos, an emerging export market for goats into Vietnam has led to increased goat numbers, with potential increases in risk of disease, particularly endoparasitism. A cross-sectional survey investigated the prevalence of gastrointestinal parasites in indigenous Kambing-Katjang goats on smallholder farms (n = 389) in 8 villages where no anthelmintic treatments were in use, providing comparisons with a case study of imported Boer crossbred goats (n = 45) on a commercial farm where intensive anthelmintic treatments were required to manage mortalities attributable to Haemonchosis...
February 15, 2018: Veterinary Parasitology
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