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Nevzat Uzuner

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https://www.readbyqxmd.com/read/27634312/levofloxacin-induced-toxic-epidermal-necrolysis-successful-therapy-with-omalizumab-anti-ige-and-pulse-prednisolone
#1
Rusen Uzun, Arzu Didem Yalcin, Betul Celik, Tangul Bulut, Ata Nevzat Yalcin
BACKGROUND Toxic epidermal necrolysis (TEN) is characterized by widespread erythematous and bullous lesions on the skin. Nowadays, considerable progress has been made in the understanding of its pathogenesis. Immunologically it is similar to graft-versus-host disease. Therefore, we may propose that TEN is a disorder of cell-mediated immunity. CASE REPORT Our patient was a 74-year-old white female who had pneumonia and was positive for hepatitis C virus (HCV), and who had been on levofloxacin therapy. After the first levofloxacin dose, erythematous dusky red macules occurred on her extremities and trunk, and on the following day, confluent purpuric lesions tended to run together over 85% of her body...
2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27136094/neurovascular-coupling-in-patients-with-relapsing-remitting-multiple-sclerosis
#2
Gulnur Tekgöl Uzuner, Nevzat Uzuner
OBJECTIVES: Also to the inflammatory demyelinating lesions and degenerative process, altered cerebrovascular reactivity or neurovascular coupling (NVC) might be considered as playing another role in the pathogenesis of multiple sclerosis. The objective of this study is to assess the NVC of patients with relapsing-remitting multiple sclerosis (RRMS) during the acute exacerbation period. PATIENTS AND METHODS: Four hundred fifty-eight patients with RRMS and 160 healthy subjects were screened for this study during the last 14 years...
July 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27008087/radioactivity-measurements-and-risk-assessments-of-spa-waters-in-some-areas-in-turkey
#3
Selcen Uzun Duran, Belgin Kucukomeroglu, Nevzat Damla, Halim Taskin, Necati Celik, Uğur Cevik, Hakan Ersoy
The current study presents the results of the activity of radionuclides in spa waters, and evaluates their radiological influences on the population consuming these waters in the Central and Eastern Black Sea regions of Turkey. Since these waters are used for therapy and consumption purposes unconsciously, their radiological impact on the people was computed by taking into consideration the annual intake through ingestion of (226)Ra, (232)Th, (40)K, (137)Cs and (222)Rn. The mean activities were estimated to be 11...
March 23, 2016: Isotopes in Environmental and Health Studies
https://www.readbyqxmd.com/read/26853139/analyses-of-the-turkish-national-intravenous-thrombolysis-registry
#4
Kursad Kutluk, Dilaver Kaya, Nazire Afsar, Ethem Murat Arsava, Vesile Ozturk, Nevzat Uzuner, Semih Giray, Mehmet Akif Topcuoglu, Levent Gungor, Hadiye Sirin, Erdem Yaka, Ozcan Ozdemir, Turgay Dalkara
BACKGROUND: The relatively late approval of use of recombinant tissue plasminogen activator (rt-PA) for acute ischemic stroke in Turkey has resulted in obvious underuse of this treatment. Here we present the analyses of the nationwide registry, which was created to prompt wider use of intravenous thrombolysis, as well as to monitor safe implementation of the treatment in our country. METHODS: Patients were registered prospectively in our database between 2006 and 2013...
May 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/25564124/surgical-site-infection-rates-in-16-cities-in-turkey-findings-of-the-international-nosocomial-infection-control-consortium-inicc
#5
MULTICENTER STUDY
Hakan Leblebicioglu, Nurettin Erben, Victor D Rosenthal, Alper Sener, Cengiz Uzun, Gunes Senol, Gulden Ersoz, Tuna Demirdal, Fazilet Duygu, Ayse Willke, Fatma Sirmatel, Nefise Oztoprak, Iftihar Koksal, Oral Oncul, Yunus Gurbuz, Ertugrul Güçlü, Huseyin Turgut, Ata Nevzat Yalcin, Davut Ozdemir, Tanil Kendirli, Turan Aslan, Saban Esen, Fatma Ulger, Ahmet Dilek, Hava Yilmaz, Mustafa Sunbul, Ilhan Ozgunes, Gaye Usluer, Metin Otkun, Ali Kaya, Necdet Kuyucu, Zeynep Kaya, Meliha Meric, Emel Azak, Gürdal Yýlmaz, Selçuk Kaya, Hülya Ulusoy, Tuncer Haznedaroglu, Levent Gorenek, Ali Acar, Ediz Tutuncu, Oguz Karabay, Gulsume Kaya, Suzan Sacar, Hülya Sungurtekin, Doğaç Uğurcan, Ozge Turhan, Sehnaz Kaya, Eylul Gumus, Oguz Dursun, Mehmet Faruk Geyik, Ahmet Şahin, Selvi Erdogan, Erdal Ince, Adem Karbuz, Ergin Çiftçi, Nevin Taşyapar, Melek Güneş
BACKGROUND: Surgical site infections (SSIs) are a threat to patient safety; however, there were no available data on SSI rates stratified by surgical procedure (SP) in Turkey. METHODS: Between January 2005 and December 2011, a cohort prospective surveillance study on SSIs was conducted by the International Nosocomial Infection Control Consortium (INICC) in 20 hospitals in 16 Turkish cities. Data from hospitalized patients were registered using the Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) methods and definitions for SSIs...
January 2015: American Journal of Infection Control
https://www.readbyqxmd.com/read/25403704/international-nosocomial-infection-control-consortium-inicc-national-report-on-device-associated-infection-rates-in-19-cities-of-turkey-data-summary-for-2003-2012
#6
Hakan Leblebicioglu, Nurettin Erben, Victor Daniel Rosenthal, Begüm Atasay, Ayse Erbay, Serhat Unal, Gunes Senol, Ayse Willke, Asu Özgültekin, Nilgün Altin, Mehmet Bakir, Oral Oncul, Gülden Ersöz, Davut Ozdemir, Ata Nevzat Yalcin, Halil Özdemir, Dinçer Yıldızdaş, Iftihar Koksal, Canan Aygun, Fatma Sirmatel, Alper Sener, Nazan Tuna, Özay Arikan Akan, Huseyin Turgut, A Pekcan Demiroz, Tanil Kendirli, Emine Alp, Cengiz Uzun, Sercan Ulusoy, Dilek Arman
BACKGROUND: Device-associated healthcare-acquired infections (DA-HAI) pose a threat to patient safety, particularly in the intensive care unit (ICU). We report the results of the International Infection Control Consortium (INICC) study conducted in Turkey from August 2003 through October 2012. METHODS: A DA-HAI surveillance study in 63 adult, paediatric ICUs and neonatal ICUs (NICUs) from 29 hospitals, in 19 cities using the methods and definitions of the U.S. NHSN and INICC methods...
2014: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/24490754/comparison-of-subclinical-left-and-right-ventricular-systolic-dysfunction-in-non-dipper-and-dipper-hypertensives-impact-of-isovolumic-acceleration
#7
COMPARATIVE STUDY
Mehmet Erturk, Ali Buturak, Hamdi Pusuroglu, Ali Kemal Kalkan, Muhammet Gurdogan, Ibrahim Faruk Akturk, Ozgur Akgul, Hale Unal Aksu, Fatih Uzun, Nevzat Uslu
UNLABELLED: Abstract Objectives: To evaluate subclinical left ventricular and right ventricular systolic impairment in dipper and non-dipper hypertensives by using isovolumic acceleration. METHODS: About 45 normotensive healthy volunteers (20 men, mean age 43 ± 9 years), 45 dipper (27 men, mean age 45 ± 9 years) and 45 non-dipper (25 men, 47 ± 7 years) hypertensives were enrolled. Isovolumic acceleration was measured by dividing the peak myocardial isovolumic contraction velocity by isovolumic acceleration time...
2014: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/24382255/cerebral-blood-flow-of-children-with-vasovagal-syncope
#8
Barsan Tugba, Kilic Zubeyir, Uzuner Nevzat, Yildirim Ali, Ucar Birsen, Demir Tevfik
INTRODUCTION: We aimed to evaluate changes in the cerebral blood supply in children during vasovagal syncope and to clarify the diagnostic value of transcranial Doppler for vasovagal syncope. MATERIALS AND METHODS: Patients were divided into three groups. Group 1 consisted of 31 patients who were symptomatic and whose head-up tilt test was positive. Group 2 comprised 21 patients who were symptomatic but whose tilt test was negative. Group 3 included 22 healthy children...
February 2015: Cardiology in the Young
https://www.readbyqxmd.com/read/24365793/does-intravenous-or-oral-high-dose-n-acetylcysteine-in-addition-to-saline-prevent-contrast-induced-nephropathy-assessed-by-cystatin-c
#9
RANDOMIZED CONTROLLED TRIAL
Mehmet Erturk, Nevzat Uslu, Sevket Gorgulu, Ertan Akbay, Gulsah Kurtulus, Ibrahim F Akturk, Ozgur Akgul, Ozgur Surgit, Fatih Uzun, Mehmet Gul, Nilgun Isiksacan, Aydin Yildirim
AIMS: The objective of this study is to determine the effect of intravenous (i.v.) or oral N-acetylcysteine (NAC) in preventing contrast-induced nephropathy (CIN) in patients with moderate-to-severe renal insufficiency undergoing intra-arterial interventions. MATERIALS AND METHODS: We studied 307 patients with estimated glomerular filtration rate of less than 60 ml/min/1.73 m undergoing an elective intra-arterial procedure. Patients were assigned randomly to three groups according to the prophylactic regimen used...
March 2014: Coronary Artery Disease
https://www.readbyqxmd.com/read/23984332/relationship-between-pulsatility-index-and-clinical-course-of-acute-ischemic-stroke-after-thrombolytic-treatment
#10
Nevzat Uzuner, Özcan Özdemir, Gülnur Tekgöl Uzuner
Background. The relationship between the arterial recanalization after intravenous recombinant tissue plasminogen activator (rtPA) and outcomes is still uncertain. The aim of our study was to evaluate whether there is an association between the pulsatility indexes (PI) of the middle cerebral artery (MCA) measured by transcranial Doppler (TCD) after iv rtPA treatment and short- and long-term outcomes in ischemic stroke patients. Methods. Forty-eight patients with acute ischemia in the MCA territory who achieved complete recanalization after the administration of intravenous thrombolytic treatment were included in the study...
2013: BioMed Research International
https://www.readbyqxmd.com/read/23735359/electrophysiological-evaluation-of-atrioventricular-conduction-disturbances-in-transcatheter-aortic-valve-implantation-with-edwards-sapien-prosthesis
#11
Abdurrahman Eksik, Mehmet Gul, Huseyin Uyarel, Ozgur Surgit, Aydin Yildirim, Nevzat Uslu, Huseyin Aksu, Selahattin Turen, Fazih Uzun, Hulusi Satılmısoglu, Mustafa Kemal Erol, Ihsan Bakir
AIMS: Permanent pacemaker requirement is a known complication after transcatheter aortic valve implantation (TAVI). The aim of the present study was to analyze the effects of Edwards SAPIEN prosthesis implantation on atrioventricular conduction. METHODS: The study included 28 patients who underwent TAVI due to severe aortic valve stenosis. An electrophysiological study was performed in the catheterization room immediately before the initial balloon valvuloplasty and immediately after Edwards SAPIEN prosthesis implantation...
June 2013: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/23698727/aspirin-resistance-in-patients-undergoing-hemodialysis-and-effect-of-hemodialysis-on-aspirin-resistance
#12
Hale Unal Aksu, Ender Oner, Omer Celik, Nilgun Isiksacan, Huseyin Aksu, Sami Uzun, Derya Yavuz, Savas Ozturk, Mehmet Gul, Nevzat Uslu
The aim of this study was to evaluate the prevalence of aspirin resistance (AR) in patients undergoing hemodialysis (HD) and to assess the effect of HD on the results of the Multiplate test. A total of 54 patients undergoing HD were included in this study. Blood samples were taken just before and after the HD session. To determine AR, we used Multiplate test. Platelet aggregation values of the study population were 363.01 ± 225.69 aggregation unit (AU) × minutes before and 375.33 ± 254.05 AU × minutes after the HD (P = ...
January 2015: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/23623158/impact-of-a-multidimensional-infection-control-approach-on-catheter-associated-urinary-tract-infection-rates-in-adult-intensive-care-units-in-10-cities-of-turkey-international-nosocomial-infection-control-consortium-findings-inicc
#13
Hakan Leblebicioglu, Gulden Ersoz, Victor Daniel Rosenthal, Ata Nevzat Yalcin, Ozay Arıkan Akan, Fatma Sirmatel, Huseyin Turgut, Davut Ozdemir, Emine Alp, Cengiz Uzun, Sercan Ulusoy, Saban Esen, Fatma Ulger, Ahmet Dilek, Hava Yilmaz, Ali Kaya, Necdet Kuyucu, Ozge Turhan, Nurgul Gunay, Eylul Gumus, Oguz Dursun, Melek Tulunay, Mehmet Oral, Necmettin Unal, Mustafa Cengiz, Leyla Yilmaz, Suzan Sacar, Hülya Sungurtekin, Doğaç Uğurcan, Mehmet Faruk Geyik, Ahmet Sahin, Selvi Erdogan, Bilgehan Aygen, Bilgin Arda, Feza Bacakoglu
BACKGROUND: We evaluate the effectiveness of a multidimensional infection control approach for the reduction of catheter-associated urinary tract infections (CAUTIs) in 13 intensive care units (ICUs) in 10 hospital members of the International Nosocomial Infection Control Consortium (INICC) from 10 cities of Turkey. METHODS: A before-after prospective active surveillance study was used to determine rates of CAUTI. The study was divided into baseline (phase 1) and intervention (phase 2)...
October 2013: American Journal of Infection Control
https://www.readbyqxmd.com/read/23581264/the-role-of-electrocardiography-in-evaluation-of-severity-of-chronic-obstructive-pulmonary-disease-in-daily-clinical-practice
#14
Faruk Aktürk, İsmail Bıyık, Cüneyt Kocaş, Mehmet Ertürk, Ahmet Arif Yalçın, Ayfer Utku Savaş, Firuzan Pınar Kuzer, Fatih Uzun, Aydın Yıldırım, Nevzat Uslu, Çağlar Çuhadaroğlu
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of chronic morbidity and mortality. Bronchial obstruction and increased pulmonary vascular resistance impairs right atrial functions. In this study, we aimed to investigate the effect of bronchial obstruction on p wave axis in patients with COPD and usefulness of electrocardiography (ECG) in the evaluation of the severity of COPD. PATIENTS AND METHODS: Ninety five patients (64 male and 31 female) included to the study...
2013: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/23305270/evaluation-of-atrial-electromechanic-delay-and-left-atrial-mechanical-functions-in-the-patients-with-secundum-type-atrial-septal-defect
#15
Mehmet Erturk, Muzaffer Aslan, Hale Unal Aksu, Ibrahim Faruk Akturk, Mehmet Gul, Fatih Uzun, Ozgur Surgit, Hasan Ari, Nevzat Uslu, Mustafa Kemal Erol
AIM: The aim of our study was to evaluate atrial electromechanical delay (AEMD) and left atrial mechanical functions (LAMF) in the patients with secundum-type atrial septal defect (ASD). METHOD: We included 72 patients with secundum type ASD in the study group and 35 gender and age-matched healthy volunteers for the control group. Maximal, minimal, and presystolic LA volumes were measured by modified Simpson method and indexed to the body surface area (BSA). Inter-AEMD, right and left intra-AEMD were measured from the lateral and septal mitral annulus and tricuspid annulus using tissue Doppler imaging (TDI)...
July 2013: Echocardiography
https://www.readbyqxmd.com/read/23274435/neonatal-tooth-in-a-preterm-infant
#16
Mehmet Nevzat Cizmeci, Mehmet Kenan Kanburoglu, Fatma Karadag Uzun, Mustafa Mansur Tatli
A neonatal tooth is defined as a tooth, which erupts within the first month of life. Herein, we report a premature infant with a neonatal tooth.
February 2013: European Journal of Pediatrics
https://www.readbyqxmd.com/read/21150383/an-analysis-of-changes-in-cerebral-blood-flood-velocities-in-depressive-pseudo-dementia-and-alzheimer-disease-patients
#17
Demet Ozbabalik Gucuyener, Cinar Yenilmez, Unal Ayranci, Figen Ozdemir, Nevzat Uzuner, Serhat Ozkan, Cem Kaptanoglu, Gazi Ozdemir
BACKGROUND: Patients with pseudo-dementia are at particular risk of being labeled as Alzheimer dementia. We thus need better diagnostic methods. In this study, we evaluated the cerebral reactivity of the posterior cerebral arteries (PCAs) during visual stimulation by transcranial Doppler ultrasonography. METHODS: The study group consisted of 13 and 11 patients suffering from pseudo-dementia and Alzheimer disease (AD), respectively, and 10 healthy controls. Visual reactivity was defined as the differences of cerebral blood flow velocity (CBFv) against the visual stimulus...
November 2010: Neurologist
https://www.readbyqxmd.com/read/20070359/effects-of-isolated-obesity-on-left-and-right-ventricular-function-a-tissue-doppler-and-strain-rate-imaging-study
#18
COMPARATIVE STUDY
Ahmet L Orhan, Nevzat Uslu, Sennur U Dayi, Zekeriya Nurkalem, Fatih Uzun, Hatice B Erer, Hakan Hasdemir, Ayse Emre, Gultekin Karakus, Ozlem Soran, John Gorcsan, Mehmet Eren
OBJECTIVE: To determine the subclinical effects of isolated obesity and its duration on cardiac function by using routine echocardiography and tissue Doppler myocardial strain rate. METHODS: Forty-nine subjects were enrolled in this study; 29 with isolated obesity defined as a body mass index > or = 30 kg/m(2) with no other cardiovascular comorbidities, and 20 nonobese controls. All subjects underwent two-dimensional and Doppler echocardiography including tissue Doppler imaging and myocardial strain rate...
March 2010: Echocardiography
https://www.readbyqxmd.com/read/19674242/foreigners-dying-in-istanbul
#19
Ibrahim Uzun, Osman Celbis, Cetin Lutfi Baydar, Nevzat Alkan, Murat Nihat Arslan
The study included 411 deaths selected from 14,647 medicolegal deaths autopsied in the Morgue Department of Forensic Medicine Institute Directorate, affiliated with the Ministry of Justice, between 1998 and 2002. Data were collected from court documents, coroner's investigation reports, and autopsy reports. The parameters of age, gender, nationality and origin, cause and place of death in foreigners dying in Istanbul were evaluated in the study. Out of 14,647 medicolegal deaths, 3.5% were foreigners from 34 different nationalities...
September 2009: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/19231193/cerebrovascular-manifestations-of-beh%C3%A3-et-s-disease
#20
Demet Ilhan, Erim Gulcan, Nevzat Uzuner, Emine Celikkas
Behçet's disease (BD) is a systemic inflammatory disease commonly characterized by oral and genital ulcerations, with skin and eye involvement. Its cause is still unknown, but vasculitis is the major pathologic feature. BD is a rare condition, seen more commonly in Turkey, as well as in Middle Eastern, Mediterranean and Far Eastern countries. Neurological involvement is reported to manifest as brainstem or corticospinal tract syndromes, increased intracranial pressure mostly related to venous sinus thrombosis or aseptic meningitis, isolated behavioral symptoms or isolated headache...
April 2009: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
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