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JOURNAL ARTICLE
Nevzat Uzuner, Gulnur Tekgol Uzuner
BACKGROUND: Cardiovascular diseases, hypertension, diabetes mellitus, dyslipidemia, and atrial fibrillation are the most common modifiable risk factors for recurrent ischemic stroke. In this study, we aimed to find the risk factors associated with more than two recurrent ischemic strokes after the first-ever stroke. METHODS: We collected the ischemic stroke patients in our stroke registry data bank, and the eligible patients were followed for recurrent ischemic stroke after 2008...
2023: Brain Circulation
#2
JOURNAL ARTICLE
Paweł Jakubczyk, Wiesław Paja, Krzysztof Pancerz, Jozef Cebulski, Joanna Depciuch, Özgur Uzun, Nevzat Tarhan, Zozan Guleken
By in vitro fertilization, oocytes can be removed and the embryo can be cultured, and then trans cervically replaced when they reach cleavage or at the blastocyst stage. The characterization of the follicular fluid is important for the treatment process. Women who applied to the Academic Hospital in vitro fertilization (IVF) Center diagnosed with idiopathic female infertility (IFI) were sought in the patient group. Demographics and clinical gonadotropin measurements of the study population were recorded. Of the 116 follicular fluid samples (n=58 male-induced infertility; n=58 control) were analyzed using the FTIR system...
June 2022: Photodiagnosis and Photodynamic Therapy
#3
MULTICENTER STUDY
Taşkın Duman, Nilgün Çınar, Derya Uludüz, Füsun Mayda Domaç, Serefnur Öztürk, Vildan Yayla, Ali Yavuz Karahan, Nazire Afşar, Mehmet Ali Sungur, Eylem Özaydın Göksu, Vedat Ali Yürekli, Hamit Genç, Uygar Utku, Şevki Şahin, Hakan Tekeli, Firdevs Ezgi Tokuç, Nevzat Uzuner, Mehmet Güney Şenol, Arda Yılmaz, Mustafa Gökçe, Seden Demirci, Özge Yılmaz Küsbeci, Gülnur Tekgöl Uzuner, Hale Zeynep Batur Çağlayan, Mustafa Açıkgöz, Hatice Kurucu, Mehmet Fatih Özdağ, Sevim Baybaş, Hakan Ekmekçi, Murat Çabalar, Mehmet Yaman, Hesna Bektaş, Yüksel Kaplan, Başak Karakurum Göksel, Aysel Milanlioğlu, Dilek Necioglu Örken, Mehmet Ufuk Aluclu, Sena Çolakoğlu, Ahmet Tüfekçi, Mustafa Bakar, Bijen Nazliel, Nida Tasçılar, Baki Göksan, Hasan Hüseyin Kozak, Cemile Handan Mısırlı, Hayriye Küçükoğlu, İpek Midi, Necdet Mengüllüoğlu, Emrah Aytaç, Nilüfer Yeşilot, Birsen İnce, Osman Özgür Yalın, Taşkın Güneş, Serdar Oruç, Serkan Demir
OBJECTIVES: Headache is the most common complaint in cerebral venous sinus thrombosis (CVST) and it may sometimes be the only symptom in these patients. This retrospective and prospective study was an investigation of any differences in terms of clinical risk factors, radiological findings, or prognosis in patients with CVST who presented with isolated headache (IH) and cases with other concomitant findings (non-isolated headache [NIH]). METHODS: A total of 1144 patients from a multicenter study of cerebral venous sinus thrombosis (VENOST study) were enrolled in this research...
January 2021: Journal of the Turkish Society of Algology
#4
MULTICENTER STUDY
Gulnur Tekgol Uzuner, Osman Ozgur Yalın, Derya Uluduz, Aynur Ozge, Nevzat Uzuner
OBJECTIVE: The relation between migraine and vascular risk factors is an unclear issue. Furthermore, the reasons for chronification are still unknown. Probably, the age-related risk and other factors leading to migraine progression will also change in the future. Under these questions, we aimed to investigate whether or not there is a specific association with vascular risk factors between several age groups and subtypes of migraine and also in their families. METHODS: A dataset (the Turkish Headache Database) from four tertiary headache centres in Turkey was used...
January 2021: Clinical Neurology and Neurosurgery
#5
JOURNAL ARTICLE
Taşkın Duman, Vildan Yayla, Derya Uludüz, Eylem Özaydın Göksu, Vedat Ali Yürekli, Hamit Genç, Uygar Utku, Nilgün Çınar, Hakan Tekeli, Mehmet Ali Sungur, Firdevs Ezgi Tokuç, Nevzat Uzuner, Mehmet Güney Şenol, Arda Yılmaz, Mustafa Gökçe, Seden Demirci, Özge Yılmaz Küsbeci, Gülnur Tekgöl Uzuner, Şevki Şahin, Hale Zeynep Batur Çağlayan, Mustafa Açıkgöz, Fatih Özdağ, Sevim Baybaş, Hakan Ekmekçi, Murat Çabalar, Mehmet Yaman, Hesna Bektaş, Yüksel Kaplan, Başak Karakurum Göksel, Aysel Milanlıoğlu, Dilek Necioğlu Örken, Mehmet Ufuk Aluçlu, Sena Çolakoğlu, Ahmet Tüfekçi, Mustafa Bakar, Bijrn Nazlıel, Nida Taşçılar, Baki Göksan, Hasan Hüseyin Kozak, Handan Mısırlı, Hayriye Küçükoğlu, İpek Midi, Necdet Mengüllüoğlu, Emrah Aytaç, Nilüfer Yeşilot, Birsen İnce, Osman Özgür Yalın, Taşkın Güneş, Serdar Oruç, Füsun Mayda Domaç, Şerefnur Öztürk, Ali Karahan, Hacı Ali Erdoğan, Nazire Afşar
INTRODUCTION: Cerebral venous and sinus thrombosis (CVST) may lead to cerebral edema and increased intracranial pressure; besides, ischemic or hemorrhagic lesions may develop. Intracerebral hemorrhages occur in approximately one-third of CVST patients. We assessed and compared the findings of the cerebral hemorrhage (CH) group and the CVST group. MATERIALS AND METHODS: In the VENOST study, medical records of 1,193 patients with CVST, aged over 18 years, were obtained from 35 national stroke centers...
2020: European Neurology
#6
JOURNAL ARTICLE
Derya Uluduz, Sevki Sahin, Taskin Duman, Serefnur Ozturk, Vildan Yayla, Nazire Afsar, Nevzat Uzuner, Ipek Midi, Nilgun Cinar, Mehmet Ali Sungur, Fusun Mayda Domac, Birsen Ince, Baki Goksan, Cemile Handan Misirli, Mustafa Bakar, Hasan Huseyin Kozak, Sena Colakoglu, Ali Yavuz Karahan, Eylem Ozaydin Goksu, Fatih Ozdag, Mehmet Guney Senol, Vedat Ali Yurekli, Ufuk Aluclu, Serkan Demir, Hayriye Kucukoglu, Serdar Oruc, Nilufer Yesilot, Ozge Yimaz Kusbeci, Bijen Nazliel, Firdevs Ezgi Ucan Tokuc, Hesna Bektas, Fatma Nida Tascilar, Emrah Aytac, Mustafa Gokce, Hale Zeynep Batur Caglayan, Ahmet Tufekci, Gulnur Uzuner, Dilek Necioglu Orken, Osman Ozgur Yalin, Uygar Utku, Arda Yilmaz, Hamit Genc, Murat Cabalar, Aysel Milanlioglu, Hakan Ekmekci, Burcu Zeydan, Sevim Baybas, Yuksel Kablan, Basak Karakurum Goksel, Mustafa Acikgoz, Hatice Kurucu, Seden Demirci, Taskin Gunes
BACKGROUND: Early diagnosis of cerebral venous sinus thrombosis (CVST) associated with reproductive health-related risk factors (RHRF) including pregnancy, puerperium, and oral contraceptive (OC) use can prevent severe neurological sequelae; thus, the symptoms must be documented in detail for each group. METHODS: Out of 1144 patients with CVST, a total of 777 women were enrolled from a multicenter for the study of cerebral venous sinus thrombosis (VENOST). Demographic, biochemical, clinical, and radiological aspects were compared for 324 cases with RHRF and 453 cases without RHRF...
2020: Stroke Research and Treatment
#7
REVIEW
Gulnur Tekgol Uzuner, Ahmet Ubur, Murat Erten, Nevzat Uzuner
Gerstmann syndrome is defined as a tetrad including agraphia, acalculia, finger agnosia, and right-left disorientation. In the case studies presented in the literature, it has been reported that Gerstmann syndrome usually appears as an incomplete tetrad of symptoms or accompanied by cognitive deficits including aphasia, alexia, apraxia and some perceptual disorders. Here, we present of the patient with left angular and supramarginal gyrus infarction affecting the parietal lobe. In addition to the symptoms mentioned above, the patient had alexia and anomic aphasia as well...
October 2020: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
#8
MULTICENTER STUDY
Derya Uluduz, Ipek Midi, Taskin Duman, Vildan Yayla, Ali Yavuz Karahan, Nazire Afsar, Eylem Ozaydin Goksu, Necdet Mengulluoglu, Emrah Aytac, Mehmet Ali Sungur, Nilufer Yesilot, Birsen Ince, Osman Ozgur Yalin, Serdar Oruc, Mehmet Guney Senol, Arda Yilmaz, Mustafa Gokce, Seden Demirci, Ozge Yilmaz Kusbeci, Gulnur Uzuner, Hale Zeynep Batur Caglayan, Mustafa Acikgoz, Hatice Kurucu, Fatih Ozdag, Sevim Baybas, Hakan Ekmekci, Murat Cabala, Mehmet Yaman, Vedat Ali Yürekli, Hakan Tekeli, Hamit Genc, Uygar Utku, Sevki Sahin, Firdevs Ezgi Ucan Tokuc, Nevzat Uzuner, Hesna Bektas, Yuksel Kablan, Basak Karakurum Goksel, Aysel Milanlioglu, Dilek Necioglu Orken, Ufuk Aluclu, Sena Colakoglu, Ahmet Tufekci, Mustafa Bakar, Bijen Nazliel, Nida Tascilar, Baki Goksan, Hasan Huseyin Kozak, Serkan Demir, Cemile Handan Mısırli, Hayriye Kucukoglu, Nilgun Cinar, Fusun Mayda Domac, Serefnur Ozturk, Taskin Gunes
PURPOSE: The aim of this study is to evaluate the presence and prognostic impact of early seizures in cerebral venous sinus thrombosis patients (CVST). METHOD: VENOST is a retrospective and prospective national multicenter observational study. CVST patients with or without epileptic seizures (ES) were analyzed and compared in terms of demographic and imaging data, causative factors, clinical variables, and prognosis in a total of 1126 patients. RESULTS: The mean age of the patients in the ES group was 39...
May 2020: Seizure: the Journal of the British Epilepsy Association
#9
JOURNAL ARTICLE
Neurological Symptoms and Evaluation of Cerebral Blood Flow Changes with Synthetic Cannabinoids Use.
Onur Karakayali, Uygar Utku, Serkan Yilmaz, Nevzat Uzuner
OBJECTIVE: To describe the cerebral haemodynamic changes that occur in patients presenting to the emergency department (ED) after synthetic cannabinoid (SC) use in order to clarify the pathophysiology of neurologic adverse effects of SCs. STUDY DESIGN: Observational study. PLACE AND DURATION OF STUDY: Emergency Department of Kocaeli Derince Training and Research Hospital, Turkey, from June 2017 to January 2018. METHODOLOGY: Patients in whom tetrahydrocannabinol was detected in the urinalysis due to SC use were included in the study...
December 2019: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
#10
MULTICENTER STUDY
Taskın Duman, Seden Demirci, Derya Uluduz, Hasan Hüseyin Kozak, Serkan Demir, Cemile Handan Mısırlı, Hayriye Küçükoğlu, Nilgün Çınar, Füsun Mayda Domaç, Şerefnur Öztürk, Mehmet Ali Sungur, Vildan Yayla, Ali Yavuz Karahan, Nazire Afşar, Eylem Özaydın Göksu, Emrah Aytaç, Nilüfer Yeşilot, Birsen İnce, Osman Özgür Yalın, Serdar Oruç, Mehmet Guney Senol, Arda Yılmaz, Mustafa Gökçe, Özge Yılmaz Küsbeci, Gulnur Uzuner, Hale Zeynep Batur Çağlayan, Mustafa Açıkgöz, Hatice Kurucu, Fatih Ozdag, Hakan Ekmekci, Murat Çabalar, Vedat Ali Yurekli, Taşkın Güneş, Hamit Genç, Uygar Utku, Şevki Şahin, Firdevs Ezgi Ucan Tokuc, Nevzat Uzuner, Hesna Bektaş, Yüksel Kablan, Başak Karakurum Göksel, Aysel Milanlıoğlu, Dilek Necioğlu Örken, Ufuk Aluclu, İpek Midi, Sena Çolakoğlu, Ahmet Tüfekçi, Mustafa Bakar, Bijen Nazlıel, Nida Taşçılar, Baki Göksan
AIM: Systemic lupus erythematosus (SLE) is an unusual risk factor for cerebral venous sinus thrombosis (CVST). As few CVST patients with SLE have been reported, little is known regarding its frequency as an underlying etiology, clinical characteristics, or long-term outcome. We evaluated a large cohort of CVST patients with SLE in a multicenter study of cerebral venous thrombosis, the VENOST study, and their clinical characteristics. MATERIAL AND METHOD: Among the 1144 CVST patients in the VENOST cohort, patients diagnosed with SLE were studied...
December 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
#11
JOURNAL ARTICLE
Nurdan Ozturk Tasar, Pelin Kosger, Nevzat Uzuner, Birsen Ucar
OBJECTIVE: We aimed to investigate the effect of ventricular septal defect (VSD) and heart failure on cerebral blood flow (CBF) in children, whether heart failure treatment improves CBF, and if there is any relationship between CBF and serum N-terminal pro-brain natriuretic peptide (NT-proBNP) level. METHOD: Forty children with VSD (13 with heart failure) aged between 1 and 36 months were studied. The control group comprised 25 healthy children in the same age group...
November 2018: Congenital Heart Disease
#12
MULTICENTER STUDY
Derya Uluduz, Ipek Midi, Taskin Duman, Sena Colakoglu, Ahmet Tüfekci, Mustafa Bakar, Bijen Nazliel, Nida Tascilar, Baki Goksan, Mehmet Ali Sungur, Hasan Huseyin Kozak, Serkan Demir, Cemile Handan Misirli, Hayriye Kucukoglu, Nilgun Cinar, Fusun Mayda Domac, Serefnur Ozturk, Vildan Yayla, Ali Yavuz Karahan, Nazire Afsar, Eylem Ozaydin Goksu, Necdet Mengulluoglu, Emrah Aytac, Nilufer Yesilot, Birsen Ince, Ozgur Osman Yalin, Serdar Oruc, Seden Demirci, Mehmet Guney Senol, Arda Yilmaz, Mustafa Gokce, Özge Yilmaz Kusbeci, Gulnur Uzuner, Hale Zeynep Batur Caglayan, Mustafa Acikgoz, Burcu Zeydan, Fatih Ozdag, Sevim Baybas, Hakan Ekmekci, Murat Cabalar, Mehmet Yaman, Vedat Ali Yurekli, Hakan Tekeli, Hamit Genc, Uygar Utku, Firdevs Ezgi Ucan Tokuc, Nevzat Uzuner, Hesna Bektas, Yuksel Kablan, Basak K Goksel, Aysel Milanlioglu, Dilek Necioglu Orken, Ufuk Aluclu
OBJECTIVE: This study was performed to determine the rate of cerebral venous sinus thrombosis (CVST) among cases of Behçet's disease (BD) included in a multicentre study of cerebral venous sinus thrombosis (VENOST). METHODS: VENOST was a retrospective and prospective national multicentre observational study that included 1144 patients with CVST. The patients were classified according to aetiologic factors, time of CVST symptom onset, sinus involvement, treatment approach and prognosis...
April 1, 2019: Rheumatology
#13
JOURNAL ARTICLE
Elyar Sadeghi-Hokmabadi, Demet Funda Baş, Mehdi Farhoudi, Aliakbar Taheraghdam, Daryoush Savadi Oskouei, Mohammad Yazdchi, Maziyar Hashemilar, Nevzat Uzuner, Reshad Mirnour, Ertugrul Colak, Atilla Özcan Özdemir
Objective . This study was set to assess the effect of renal dysfunction on outcome of stroke patients treated with intravenous thrombolysis (IVT). Methods . This multicenter research involved 403 patients from January 2009 to March 2015. Patients were divided into two groups: (1) control group with GFR ≥ 45 mL/min/1.73 m2 and (2) low GFR group with GFR < 45 mL/min/1.73 m2 . Outcome measurements were poor outcome (mRS 3-6) and mortality at 3 months and symptomatic intracerebral hemorrhage (SICH) within the first 24-36 hours...
2017: Stroke Research and Treatment
#14
JOURNAL ARTICLE
Rusen Uzun, Arzu Didem Yalcin, Betul Celik, Tangul Bulut, Ata Nevzat Yalcin
BACKGROUND Toxic epidermal necrolysis (TEN) is characterized by widespread erythematous and bullous lesions on the skin. Nowadays, considerable progress has been made in the understanding of its pathogenesis. Immunologically it is similar to graft-versus-host disease. Therefore, we may propose that TEN is a disorder of cell-mediated immunity. CASE REPORT Our patient was a 74-year-old white female who had pneumonia and was positive for hepatitis C virus (HCV), and who had been on levofloxacin therapy. After the first levofloxacin dose, erythematous dusky red macules occurred on her extremities and trunk, and on the following day, confluent purpuric lesions tended to run together over 85% of her body...
September 16, 2016: American Journal of Case Reports
#15
JOURNAL ARTICLE
Gulnur Tekgöl Uzuner, Nevzat Uzuner
OBJECTIVES: Also to the inflammatory demyelinating lesions and degenerative process, altered cerebrovascular reactivity or neurovascular coupling (NVC) might be considered as playing another role in the pathogenesis of multiple sclerosis. The objective of this study is to assess the NVC of patients with relapsing-remitting multiple sclerosis (RRMS) during the acute exacerbation period. PATIENTS AND METHODS: Four hundred fifty-eight patients with RRMS and 160 healthy subjects were screened for this study during the last 14 years...
July 2016: Clinical Neurology and Neurosurgery
#16
JOURNAL ARTICLE
Selcen Uzun Duran, Belgin Kucukomeroglu, Nevzat Damla, Halim Taskin, Necati Celik, Uğur Cevik, Hakan Ersoy
The current study presents the results of the activity of radionuclides in spa waters, and evaluates their radiological influences on the population consuming these waters in the Central and Eastern Black Sea regions of Turkey. Since these waters are used for therapy and consumption purposes unconsciously, their radiological impact on the people was computed by taking into consideration the annual intake through ingestion of 226 Ra, 232 Th, 40 K, 137 Cs and 222 Rn. The mean activities were estimated to be 11...
March 2017: Isotopes in Environmental and Health Studies
#17
MULTICENTER STUDY
Kursad Kutluk, Dilaver Kaya, Nazire Afsar, Ethem Murat Arsava, Vesile Ozturk, Nevzat Uzuner, Semih Giray, Mehmet Akif Topcuoglu, Levent Gungor, Hadiye Sirin, Erdem Yaka, Ozcan Ozdemir, Turgay Dalkara
BACKGROUND: The relatively late approval of use of recombinant tissue plasminogen activator (rt-PA) for acute ischemic stroke in Turkey has resulted in obvious underuse of this treatment. Here we present the analyses of the nationwide registry, which was created to prompt wider use of intravenous thrombolysis, as well as to monitor safe implementation of the treatment in our country. METHODS: Patients were registered prospectively in our database between 2006 and 2013...
May 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
#18
MULTICENTER STUDY
Hakan Leblebicioglu, Nurettin Erben, Victor D Rosenthal, Alper Sener, Cengiz Uzun, Gunes Senol, Gulden Ersoz, Tuna Demirdal, Fazilet Duygu, Ayse Willke, Fatma Sirmatel, Nefise Oztoprak, Iftihar Koksal, Oral Oncul, Yunus Gurbuz, Ertugrul Güçlü, Huseyin Turgut, Ata Nevzat Yalcin, Davut Ozdemir, Tanil Kendirli, Turan Aslan, Saban Esen, Fatma Ulger, Ahmet Dilek, Hava Yilmaz, Mustafa Sunbul, Ilhan Ozgunes, Gaye Usluer, Metin Otkun, Ali Kaya, Necdet Kuyucu, Zeynep Kaya, Meliha Meric, Emel Azak, Gürdal Yýlmaz, Selçuk Kaya, Hülya Ulusoy, Tuncer Haznedaroglu, Levent Gorenek, Ali Acar, Ediz Tutuncu, Oguz Karabay, Gulsume Kaya, Suzan Sacar, Hülya Sungurtekin, Doğaç Uğurcan, Ozge Turhan, Sehnaz Kaya, Eylul Gumus, Oguz Dursun, Mehmet Faruk Geyik, Ahmet Şahin, Selvi Erdogan, Erdal Ince, Adem Karbuz, Ergin Çiftçi, Nevin Taşyapar, Melek Güneş
BACKGROUND: Surgical site infections (SSIs) are a threat to patient safety; however, there were no available data on SSI rates stratified by surgical procedure (SP) in Turkey. METHODS: Between January 2005 and December 2011, a cohort prospective surveillance study on SSIs was conducted by the International Nosocomial Infection Control Consortium (INICC) in 20 hospitals in 16 Turkish cities. Data from hospitalized patients were registered using the Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) methods and definitions for SSIs...
January 2015: American Journal of Infection Control
#19
JOURNAL ARTICLE
Hakan Leblebicioglu, Nurettin Erben, Victor Daniel Rosenthal, Begüm Atasay, Ayse Erbay, Serhat Unal, Gunes Senol, Ayse Willke, Asu Özgültekin, Nilgün Altin, Mehmet Bakir, Oral Oncul, Gülden Ersöz, Davut Ozdemir, Ata Nevzat Yalcin, Halil Özdemir, Dinçer Yıldızdaş, Iftihar Koksal, Canan Aygun, Fatma Sirmatel, Alper Sener, Nazan Tuna, Özay Arikan Akan, Huseyin Turgut, A Pekcan Demiroz, Tanil Kendirli, Emine Alp, Cengiz Uzun, Sercan Ulusoy, Dilek Arman
BACKGROUND: Device-associated healthcare-acquired infections (DA-HAI) pose a threat to patient safety, particularly in the intensive care unit (ICU). We report the results of the International Infection Control Consortium (INICC) study conducted in Turkey from August 2003 through October 2012. METHODS: A DA-HAI surveillance study in 63 adult, paediatric ICUs and neonatal ICUs (NICUs) from 29 hospitals, in 19 cities using the methods and definitions of the U.S. NHSN and INICC methods...
November 18, 2014: Annals of Clinical Microbiology and Antimicrobials
#20
COMPARATIVE STUDY
Mehmet Erturk, Ali Buturak, Hamdi Pusuroglu, Ali Kemal Kalkan, Muhammet Gurdogan, Ibrahim Faruk Akturk, Ozgur Akgul, Hale Unal Aksu, Fatih Uzun, Nevzat Uslu
UNLABELLED: Abstract Objectives: To evaluate subclinical left ventricular and right ventricular systolic impairment in dipper and non-dipper hypertensives by using isovolumic acceleration. METHODS: About 45 normotensive healthy volunteers (20 men, mean age 43 ± 9 years), 45 dipper (27 men, mean age 45 ± 9 years) and 45 non-dipper (25 men, 47 ± 7 years) hypertensives were enrolled. Isovolumic acceleration was measured by dividing the peak myocardial isovolumic contraction velocity by isovolumic acceleration time...
2014: Clinical and Experimental Hypertension: CHE
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