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https://www.readbyqxmd.com/read/28817571/automated-segmentation-of-mouse-oct-volumes-asimov-validation-clinical-study-of-a-light-damage-model
#1
Bhavna Josephine Antony, Byung-Jin Kim, Andrew Lang, Aaron Carass, Jerry L Prince, Donald J Zack
The use of spectral-domain optical coherence tomography (SD-OCT) is becoming commonplace for the in vivo longitudinal study of murine models of ophthalmic disease. Longitudinal studies, however, generate large quantities of data, the manual analysis of which is very challenging due to the time-consuming nature of generating delineations. Thus, it is of importance that automated algorithms be developed to facilitate accurate and timely analysis of these large datasets. Furthermore, as the models target a variety of diseases, the associated structural changes can also be extremely disparate...
2017: PloS One
https://www.readbyqxmd.com/read/28817253/cuts-guided-deterministic-buckling-in-arrays-of-soft-parallel-plates-for-multifunctionality
#2
Gaojian Lin, Dengteng Ge, Yichao Tang, Yu Xia, Gaoxiang Wu, Lin Han, Shu Yang, Jie Yin
Harnessing buckling instability in soft materials offers an effective strategy to achieve multifunctionality. Despite great efforts in controlling the wrinkling behaviors of film-based systems and buckling of periodic structures, the benefits of classical plate buckling in soft materials remain largely unexplored. The challenge lies in the intrinsic indeterminate characteristics of buckling, leading to geometric frustration and random orientations. Here, we report the controllable global order in constrained buckling of arrays of parallel plates made of hydrogels and elastomers on rigid substrates...
August 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28817146/controlled-deposition-of-palladium-nanodendrites-on-the-tips-of-gold-nanorods-and-their-enhanced-catalytic-activity
#3
Gaoxing Su, Huaqiao Jiang, Hongyan Zhu, Jing-Jing Lv, Guohai Yang, Bing Yan, Jun-Jie Zhu
Plasmonic Au-Pd nanostructures have drawn significant attention for use in heterogeneous catalysis. In this study, palladium nanodendrite-tipped gold nanorods (PdND-T-AuNRs) were subjected to a facile fabrication under mild reaction conditions. The palladium amounts on the two tips were tunable. In the preparation of PdND-T-AuNRs, dense capped AuNRs, a low reaction temperature, and suitable stabilizing agents were identified as critical reaction parameters for controlling palladium nanodendrites deposited on both ends of AuNRs...
August 17, 2017: Nanoscale
https://www.readbyqxmd.com/read/28817086/non-destructive-analysis-of-the-internal-anatomical-structures-of-mosquito-specimens-using-optical-coherence-tomography
#4
Naresh Kumar Ravichandran, Ruchire Eranga Wijesinghe, Seung-Yeol Lee, Kwang Shik Choi, Mansik Jeon, Hee-Young Jung, Jeehyun Kim
The study of mosquitoes and analysis of their behavior are of crucial importance in the on-going efforts to control the alarming increase in mosquito-borne diseases. Furthermore, a non-destructive and real-time imaging technique to study the anatomical features of mosquito specimens can greatly aid the study of mosquitoes. In this study, we demonstrate the three-dimensional imaging capabilities of optical coherence tomography (OCT) for structural analysis of Anopheles sinensis mosquitoes. The anatomical features of An...
August 17, 2017: Sensors
https://www.readbyqxmd.com/read/28816881/the-shikani-optical-stylet-as-an-alternative-to-awake-fiberoptic-intubation-in-patients-at-risk-of-secondary-cervical-spine-injury-a-randomized-controlled-trial
#5
Rabab S S Mahrous, Aly M M Ahmed
BACKGROUND: Conventional intubation of the trachea and consequent prone positioning of anesthetized patients with cervical spine instability may result in secondary neurological injury. Historically, flexible fiberoptics used to be the chief choice for patients presenting with cervical spine instability surgery with difficult airway. Recently, the rigid optical stylets have shown promise in assisting difficult intubations. PURPOSE: The aim of the present study was to compare the efficacy of Shikani optical stylet (SOS) with the flexible fiberscope for awake intubation in patients with cervical spine instability...
August 14, 2017: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/28816483/effect-of-travel-speed-on-the-visual-control-of-steering-toward-a-goal
#6
Rongrong Chen, Diederick C Niehorster, Li Li
Previous studies have proposed that people can use visual cues such as the instantaneous direction (i.e., heading) or future path trajectory of travel specified by optic flow or target visual direction in egocentric space to steer or walk toward a goal. In the current study, we examined what visual cues people use to guide their goal-oriented locomotion and whether their reliance on such visual cues changes as travel speed increases. We presented participants with optic flow displays that simulated their self-motion toward a target at various travel speeds under two viewing conditions in which we made target egocentric direction available or unavailable for steering...
August 17, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28816288/-recombinant-human-transforming-growth-factor-%C3%AE-1-promotes-dental-pulp-stem-cells-proliferation-and-mineralization
#7
W Q Jia, Y M Zhao, L H Ge
OBJECTIVE: To explore suitable concentration of recombinant human transforming growth factor β1 (rhTGF-β1) usage and study the effect of rhTGF-β1 on differentiation of dental pulp stem cells (DPSCs). METHODS: DPSCs were isolated from the undiseased third molars of people aged 18-25 years and cultured according to instructions in vitro. Different concentrations (1 , 6 , 10 μg/L) of rhTGF-β1 were added to the culture medium to examine DPSCs proliferation by CCK-8 (cell counting kit-8) assay...
August 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28816146/quality-assessment-of-stereotactic-radiosurgery-of-a-melanoma-brain-metastases-model-using-a-mouselike-phantom-and-the-small-animal-radiation-research-platform
#8
Cheng-Chia Wu, Kunal R Chaudhary, Yong Hum Na, David Welch, Paul J Black, Adam M Sonabend, Peter Canoll, Yvonne M Saenger, Tony J C Wang, Cheng-Shie Wuu, Tom K Hei, Simon K Cheng
PURPOSE: To establish a novel preclinical model for stereotactic radiosurgery (SRS) with combined mouselike phantom quality assurance in the setting of brain metastases. METHODS AND MATERIALS: C57B6 mice underwent intracranial injection of B16-F10 melanoma cells. T1-weighted postcontrast magnetic resonance imaging (MRI) was performed on day 11 after injection. The MRI images were fused with cone beam computed tomography (CBCT) images using the Small Animal Radiation Research Platform (SARRP)...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28816042/rapid-and-reliable-detection-of-alkaline-phosphatase-by-a-hot-spots-amplification-strategy-based-on-well-controlled-assembly-on-single-nanoparticle
#9
Yi Zeng, Jia-Qiang Ren, Shaokai Wang, Jiaming Mai, Bing Qu, Yan Zhang, Ai-Guo Shen, Jiming Hu
The first appeal of clinical assay is always accurate and rapid. For alkaline phosphatase (ALP) monitoring in medical treatment, a rapid, reliable surface-enhanced Raman scattering (SERS) test kit is designed based on a "hot spots" amplification strategy. Consisting of alkyne-tagged Au nanoparticles (NPs), Ag+, and enzyme substrate, the packaged test kit can achieve one-step clinical assay of ALP in human serum within several minutes, while the operation is simple as it directly inputs the sample into the test kit...
August 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28815807/molybdenum-oxides-from-fundamentals-to-functionality
#10
REVIEW
Isabela Alves de Castro, Robi Shankar Datta, Jian Zhen Ou, Andres Castellanos-Gomez, Sharath Sriram, Torben Daeneke, Kourosh Kalantar-Zadeh
The properties and applications of molybdenum oxides are reviewed in depth. Molybdenum is found in various oxide stoichiometries, which have been employed for different high-value research and commercial applications. The great chemical and physical characteristics of molybdenum oxides make them versatile and highly tunable for incorporation in optical, electronic, catalytic, bio, and energy systems. Variations in the oxidation states allow manipulation of the crystal structure, morphology, oxygen vacancies, and dopants, to control and engineer electronic states...
August 16, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28815776/a-photochemical-and-electrochemical-triggered-bis-hydrazone-switch
#11
Mónica A Gordillo, Mónica Soto-Monsalve, Christian C Carmona-Vargas, Gustavo Gutierrez, Richard F D'vries, Jean-Marie Lehn, Manuel N Chaur
Herein, we report the synthesis of a double hydrazone capable of undergoing photochemical E/Z isomerization through the imine double bonds. The bis(hydrazone) 1-E,E can be considered as a "two-arm" system in which the controlled movement of each arm is obtained by photo-modulation, making possible the appearance of two isolable metastable isomeric states 1-E,Z and 1-Z,Z. Such states are characterized by very specific structural, optical and electrochemical properties. The latter, allows the reversible return from either 1-E,Z or 1-Z,Z to the 1-E,E state...
August 17, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28815774/excitonically-coupled-states-in-crystalline-coordination-networks
#12
Ritesh Haldar, Antoine Mazel, Reetu Joseph, Michael Adams, Ian Howard, Bryce Richards, Manuel Tsotsalas, Engelbert Redel, Stephane Diring, Fabrice Odobel, Christof Wöll
When chromophores are brought into close proximity, noncovalent interactions (π-π/CH-π) can lead to the formation of excitonically coupled states, which bestow new photophysical properties upon the aggregates. Since the properties of the new states not only depend on the strength of intermolecular interactions, but also on the relative orientation, supramolecular assemblies, where these parameters can be varied in a deliberate fashion, provide novel possibilities for the control of photophysical properties...
August 17, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28815393/pattern-noise-pano-a-new-automated-functional-glaucoma-test
#13
Sylvain El-Khoury, Thomas Hannen, Diana Carmen Dragnea, Faustin Ngounou, Paul-Rolf Preußner
PURPOSE: To present a newly developed visual field device (pattern noise: PANO) designed to be sensitive to glaucoma defects, cost-effective, material-practical and easy to repair and therefore particularly suited for low-income countries, where glaucoma can be highly prevalent (e.g. sub-Saharan Africa). METHODS: This is primarily a descriptive paper, but it also includes a prospective matched case-control pilot study. Hardware, stimulus, target configuration, testing strategy and result sheet are described...
August 16, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28815194/focusing-light-inside-dynamic-scattering-media-with-millisecond-digital-optical-phase-conjugation
#14
Yan Liu, Cheng Ma, Yuecheng Shen, Junhui Shi, Lihong V Wang
Wavefront shaping based on digital optical phase conjugation (DOPC) focuses light through or inside scattering media, but the low speed of DOPC prevents it from being applied to thick, living biological tissue. Although a fast DOPC approach was recently developed, the reported single-shot wavefront measurement method does not work when the goal is to focus light inside, instead of through, highly scattering media. Here, using a ferroelectric liquid crystal based spatial light modulator, we develop a simpler but faster DOPC system that focuses light not only through, but also inside scattering media...
February 2017: Optica
https://www.readbyqxmd.com/read/28814822/high-visibility-in-two-color-above-threshold-photoemission-from-tungsten-nanotips-in-a-coherent-control-scheme
#15
Timo Paschen, Michael Förster, Michael Krüger, Christoph Lemell, Georg Wachter, Florian Libisch, Thomas Madlener, Joachim Burgdörfer, Peter Hommelhoff
In this article, we present coherent control of above-threshold photoemission from a tungsten nanotip achieving nearly perfect modulation. Depending on the pulse delay between fundamental ([Formula: see text]) and second harmonic ([Formula: see text]) pulses of a femtosecond fiber laser at the nanotip, electron emission is significantly enhanced or depressed during temporal overlap. Electron emission is studied as a function of pulse delay, optical near-field intensities, DC bias field and final photoelectron energy...
June 17, 2017: Journal of Modern Optics
https://www.readbyqxmd.com/read/28814817/conjugated-polymers-mediate-effective-activation-of-the-mammalian-ion-channel-transient-receptor-potential-vanilloid-1
#16
F Lodola, N Martino, G Tullii, G Lanzani, M R Antognazza
Selective and rapid regulation of ionic channels is pivotal to the understanding of physiological processes and has a crucial impact in developing novel therapeutic strategies. Transient Receptor Potential (TRP) channels are emerging as essential cellular switches that allow animals to respond to their environment. In particular, the Vanilloid Receptor 1 (TRPV1), besides being involved in the body temperature regulation and in the response to pain, has important roles in several neuronal functions, as cytoskeleton dynamics, injured neurons regeneration, synaptic plasticity...
August 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28814418/comparing-glaucomatous-disc-change-using-stereo-disc-viewing-and-the-matchedflicker-programme-in-glaucoma-experts-and-trainees
#17
Jamie L Schaefer, Alissa M Meyer, Cooper D Rodgers, Nicole C Rosenberg, Anthony J Leoncavallo, Zachary L Lukowski, Anthony B Greer, Gina M Martorana, Baiming Zou, Jonathan J Shuster, L Jay Katz, Joel S Schuman, Michael A Kass, Mark B Sherwood
BACKGROUND/AIMS: The objective of this study is to evaluate the accuracy and speed of trainees and experienced glaucoma specialists using the MatchedFlicker software against the manual examination of stereoscopic disc photographs for detecting glaucomatous optic disc change. METHODS: Three experienced glaucoma specialists, two resident ophthalmologists and one glaucoma fellow from multiple institutions independently evaluated the same 140 image pairs from 100 glaucomatous/ocular hypertensive eyes using a handheld stereo viewer and the MatchedFlicker programme...
August 16, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28814415/optical-coherence-tomography-angiography-enhances-the-detection-of-optic-nerve-damage-in-multiple-sclerosis
#18
Rebecca I Spain, Liang Liu, Xinbo Zhang, Yali Jia, Ou Tan, Dennis Bourdette, David Huang
BACKGROUND: Quantitative assessment of optic nerve damage is important in the evaluation of optic neuritis (ON) and multiple sclerosis (MS). OBJECTIVE: To detect optic nerve damage using optical coherence tomography (OCT) and OCT angiography in MS. METHODS: Peripapillary retinal nerve fibre layer (NFL) thickness, macular ganglion cell complex (GCC) thickness and Optic Nerve Head Flow Index (ONH-FI) were measured. The ONH-FI was defined as flow signal averaged over the optic disc...
August 16, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28814077/temperature-dependent-two-dimensional-transition-metal-dichalcogenide-heterostructures-controlled-synthesis-and-their-properties
#19
Fei Chen, Lei Wang, Xiaohong Ji, Qinyuan Zhang
Vertical stacked and lateral stitched heterostructures consisting of two-dimensional (2D) transition metal dichalcogenides (TMDCs) are predicted to possess novel electronic and optical properties, which offer the opportunities for the development of next-generation of electronic and optoelectronic devices. In the present work, we report temperature-dependent synthesis of 2D TMDCs heterostructures on Si/SiO2 substrate, including MoS2-WS2, WS2-MoS2-WS2, Mo1-xWxS2-WS2, and Mo1-xWxS2 alloyed bilayer heterostructures by ambient pressure chemical vapor deposition (CVD)...
August 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28813938/online-sparse-gaussian-process-based-human-motion-intent-learning-for-an-electrically-actuated-lower-extremity-exoskeleton
#20
Yi Long, Zhi-Jiang Du, Chao-Feng Chen, Wei Dong, Wei-Dong Wang
The most important step for lower extremity exoskeleton is to infer human motion intent (HMI), which contributes to achieve human exoskeleton collaboration. Since the user is in the control loop, the relationship between human robot interaction (HRI) information and HMI is nonlinear and complicated, which is difficult to be modeled by using mathematical approaches. The nonlinear approximation can be learned by using machine learning approaches. Gaussian Process (GP) regression is suitable for high-dimensional and small-sample nonlinear regression problems...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
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