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https://www.readbyqxmd.com/read/28813302/divorce-and-health-good-data-in-need-of-better-theory
#1
REVIEW
David A Sbarra, James A Coan
A very large literature links the experiences of marital separation and divorce to risk for a range of poor distal health outcomes, including early death. What is far less clear, however, is the mechanistic pathways that convey this risk. Several plausible mechanisms are identified in the literature, and the central thesis of this paper is that the empirical study of divorce and health will benefit enormously from a renewed reliance on theory to dictate how these mechanisms of action may unfold over time. This review emphasizes the roles of attachment and social baseline theories in making specific mechanistic predictions and highlights the ways in which these perspectives can contribute new empirical knowledge on risk and resilience following marital dissolution...
February 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28803166/advanced-age-in-mares-affects-endometrial-secretion-of-arachidonic-acid-metabolites-during-equine-subclinical-endometritis
#2
Marta J Siemieniuch, Katarzyna Gajos, Roland Kozdrowski, Marcin Nowak
Even if mares continue to breed up to an advanced age, in aging mares reproductive failure is quite common. Subclinical endometritis, which occurs more often in aging mares than in younger counterparts, may cause prolongation or shortening of the inter-estrus period or the corpus luteum lifespan. We hypothesized that during subclinical endometritis the secretion of selected arachidonic acid metabolites may differ in aging mares compared to younger females. To verify this thesis, ex vivo organ cultures of endometrium were established with subsequent measurements of concentrations of prostaglandin E2 (PGE2), 6-keto-PGF1α and both leukotrienes (LTs), LTB4 and LTC4 in the culture supernatants...
July 29, 2017: Theriogenology
https://www.readbyqxmd.com/read/28803047/puromycin-based-inhibitors-of-aminopeptidases-for-the-potential-treatment-of-hematologic-malignancies
#3
Rohit Singh, Jessica Williams, Robert Vince
Substantial progress has been described in the study of puromycin and its analogs for antibiotic properties. However, the peptidase inhibitory activity of related analogs has not been explored as extensively. Specifically, inhibiting aminopeptidases for achieving antitumor effect has been sparsely investigated. Herein, we address this challenge by reporting the synthesis of a series of analogs based on the structural template of puromycin. We also present exhaustive biochemical and in vitro analyses in support of our thesis...
July 26, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28792912/adverse-pregnancy-outcomes-and-inherited-thrombophilia
#4
Dominik Dłuski, Radzisław Mierzyński, Elżbieta Poniedziałek-Czajkowska, Bożena Leszczyńska-Gorzelak
AIM: (1) To evaluate the prevalence of inherited thrombophilia in pregnant women with adverse pregnancy outcomes: intrauterine growth retardation (IUGR), preeclampsia (PE) and placental abruption. (2) To assess the impact of inherited thrombophilia on the nature of obstetric complications. (3) To assess levels of protein S, protein C, antithrombin III and homocysteine in pregnant women with adverse pregnancy outcomes. SUBJECTS AND METHODS: The study comprised 162 pregnant women...
August 9, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28791892/voluntarist-theology-and-early-modern-science-the-matter-of-the-divine-power-absolute-and-ordained
#5
Francis Oakley
This paper is an intervention in the debate inaugurated by Peter Harrison in 2002 when he called into question the validity of what has come to be called 'the voluntarism and early-modern science thesis'. Though it subsequently drew support from such historians of science as J. E. McGuire, Margaret Osler, and Betty-Joe Teeter Dobbs, the origins of the thesis are usually traced back to articles published in 1934 and 1961 respectively by the philosopher Michael Foster and the historian of ideas Francis Oakley...
August 1, 2017: History of Science; An Annual Review of Literature, Research and Teaching
https://www.readbyqxmd.com/read/28783230/the-madoffization-of-irish-society-from-ponzi-finance-to-sociological-critique
#6
Lee F Monaghan, Micheal O'Flynn
Financialization and neoliberal policy created the Celtic Tiger. This economic 'miracle' furthered creditors' and property developers' speculative interests, leading to an unstable financial pyramid that eventually imploded in 2008 with catastrophic consequences for Irish society. Using the sociological imagination as social critique, this paper offers a lens on fictitious capital and Ponzi finance in the context of Ireland's boom and bust. Critique is advanced using the Madoffization of society thesis, a sociological heuristic that draws formal comparisons between Bernie Madoff's US$65 billion Ponzi scheme, which collapsed in 2008, and financialized capitalism...
August 7, 2017: British Journal of Sociology
https://www.readbyqxmd.com/read/28779872/embodied-cognition-and-the-cerebellum-perspectives-from-the-dysmetria-of-thought-and-the-universal-cerebellar-transform-theories
#7
Xavier Guell, John D E Gabrieli, Jeremy D Schmahmann
In this report, we analyze the relationship between embodied cognition and current theories of the cerebellum, particularly the Dysmetria of Thought theory and the concept of the Universal Cerebellar Transform (UCT). First, we describe the UCT and the Dysmetria of Thought theories, highlight evidence supporting these hypotheses and discuss their mechanisms, functions and relevance. We then propose the following relationships. (i) The UCT strengthens embodied cognition because it provides an example of embodiment where the nature and intensity of the dependence between cognitive, affective and sensorimotor processes are defined...
July 14, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28764723/systematic-review-on-traditional-medicinal-plants-used-for-the-treatment-of-malaria-in-ethiopia-trends-and-perspectives
#8
REVIEW
Getachew Alebie, Befikadu Urga, Amha Worku
BACKGROUND: Ethiopia is endowed with abundant medicinal plant resources and traditional medicinal practices. However, available research evidence on indigenous anti-malarial plants is highly fragmented in the country. The present systematic review attempted to explore, synthesize and compile ethno-medicinal research evidence on anti-malarial medicinal plants in Ethiopia. METHODS: A systematic web search analysis and review was conducted on research literature pertaining to medicinal plants used for traditional malaria treatment in Ethiopia...
August 1, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28764201/the-need-and-importance-of-incorporating-academic-research-results-in-to-the-curricula-of-ayurveda-in-india
#9
Janmejaya Samal, Ranjit Kumar Dehury
Every year a noticeable number of MD and PhD students pass out from various Ayurveda colleges across the country. Each of these Post Graduate (PG) and doctoral students do submit a research thesis as a part of fulfillment of their respective degrees. As on 01/04/2015 there were 98 PG Ayurveda colleges in India with an admission capacity of 2441 seats each year. Moreover many of the post graduate institutes provide doctoral level (PhD) education which is primarily involved with research thesis. Such meticulous research carried out under the supervision of an academic expert should not go in vein and hence the research findings need to be slotted in to the respective areas and disciplines of Ayurveda syllabus...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28758181/how-cranial-shapes-led-to-contemporary-ethnic-classification-a-historical-view
#10
Deniz Belen
In medical literature various ethnic terms, like Caucasian or Mongolian, are sporadically cited for indicating the relationship between certain disorders and geographical origin of individuals. Few of scientists recognize that those definitions are stemmed from a medical thesis written by the German physician Johann Friedrich Blumenbach in 1775. Through considering cranial shapes, Blumenbach proposed five race varieties including the Caucasian, the Mongolian, the Malayan, the Ethiopian, and the American. While he favored only beauty his contemporaries reclaimed an intellectuality arrangement among those race types and gave the highest credibility to Caucasian, which therefore, besides defining an ethnicity, has conveyed a discriminatory meaning...
June 20, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28753833/training-research-and-working-conditions-for-urology-residents-in-germany-a-contemporary-survey
#11
Hendrik Borgmann, Hannah K Arnold, Christian P Meyer, Johannes Bründl, Justus König, Tim Nestler, Christian Ruf, Julian Struck, Johannes Salem
BACKGROUND: Excellent uniform training of urology residents is crucial to secure both high-quality patient care and the future of our specialty. Residency training has come under scrutiny following the demands of subspecialized care, economical aspects, and working hour regulations. OBJECTIVE: To comprehensively assess the surgical training, research opportunities, and working conditions among urology residents in Germany. DESIGN, SETTING, AND PARTICIPANTS: We sent a 29-item online survey via email to 721 members of the German Society of Residents in Urology...
December 16, 2016: European Urology Focus
https://www.readbyqxmd.com/read/28742713/does-prolonged-enteral-feeding-with-supplemental-omega-3-fatty-acids-impact-on-recovery-post-esophagectomy-results-of-a-randomized-double-blind-trial
#12
Laura A Healy, Aoife Ryan, Suzanne L Doyle, Éadaoin Bríd Ní Bhuachalla, Samantha Cushen, Ricardo Segurado, Thomas Murphy, Narayanasamy Ravi, Claire L Donohoe, John V Reynolds
OBJECTIVE: This randomized controlled trial (RCT) hypothesized that prolonged enteral nutrition (EN) with supplemental eicosapentanoic acid (EPA), an omega-3 fatty acid with immune and anabolic properties, may impact on clinical and nutritional outcomes. BACKGROUND: Esophagectomy is associated with significant weight loss and catabolism, and negatively impacts quality of life (QL). Strategies to counter sustained catabolism have therapeutic rationale. METHODS: This multicenter, double-blind, placebo-controlled RCT was powered on a 5% difference in lean body mass (LBM) at 1 month...
July 24, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28723991/health-inequalities-a-global-perspective
#13
Mauricio Lima Barreto
The objective of this article is to present health inequalities as a global problem which afflicts the populations of the poorest countries, but also those of the richest countries, and whose persistence represents one of the most serious and challenging health problems worldwide. Two components of global inequalities are highlighted: inequalities between groups within the same society, and inequalities between nations. The understanding that many of these inequalities are unjust, and therefore inequities, is largely derived from the inequalities that are identified between the various social groups of a given society...
July 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28723238/the-poetics-of-mourning-and-faith-based-intervention-in-maladaptive-grieving-processes-in-ethiopia
#14
Jeylan Wolyie Hussein
The paper is an inquiry into the poetics of mourning and faith-based intervention in maladaptive grieving processes in Ethiopia. The paper discusses the ways loss is signified and analyses the meanings of ethno-cultural and psychospiritual practices employed to deal with maladaptive grief processes and their psychological and emotional after-effects. Hermeneutics provided the methodological framework and informed the analysis. The thesis of the paper is that the poetics of mourning and faith-based social interventions are interactionally based meaning making processes...
July 19, 2017: Death Studies
https://www.readbyqxmd.com/read/28718437/mutations-cancer-and-the-telomere-length-paradox
#15
REVIEW
Abraham Aviv, James J Anderson, Jerry W Shay
Individuals with short telomeres should be at increased risk for cancer, since short telomeres lead to genomic instability - a hallmark of cancer. However, individuals with long telomeres also display an increased risk for major cancers, thus creating a cancer-telomere length (TL) paradox. The two-stage clonal expansion model we propose is based on the thesis that a series of mutational hits (1st Hit) at the stem-cell level generates a clone with replicative advantage. A series of additional mutational hits (2nd Hit) transforms the expanding clone into cancer...
April 2017: Trends in Cancer
https://www.readbyqxmd.com/read/28713189/the-animal-sensorimotor-organization-a-challenge-for-the-environmental-complexity-thesis
#16
Fred Keijzer, Argyris Arnellos
Godfrey-Smith's environmental complexity thesis (ECT) is most often applied to multicellular animals and the complexity of their macroscopic environments to explain how cognition evolved. We think that the ECT may be less suited to explain the origins of the animal bodily organization, including this organization's potentiality for dealing with complex macroscopic environments. We argue that acquiring the fundamental sensorimotor features of the animal body may be better explained as a consequence of dealing with internal bodily-rather than environmental complexity...
2017: Biology & Philosophy
https://www.readbyqxmd.com/read/28713090/-the-teaching-of-medical-ethics-in-medical-school
#17
Mateusz Wilk, Tomasz Kirmes, Karolina Sypel, Izabela Paluch, Małgorzata Chowaniec, Czesław Chowaniec
Medical ethics constitutes some kind of core, which enables the physicians to decide in complicated clinical situations. This subject is taught during medical studies through only one semester. Number of teaching hours designed for this crucial in later physician's practice subject is insufficient. Additional problem in teaching process is inconsistence between the Law and the Code of Medical Ethics. As a result it causes alarmingly weak preparation of students to take practical decisions according to ethical and moral values of the Code of Medical Ethics...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28706101/low-value-clinical-practices-in-injury-care-a-scoping-review-protocol
#18
Lynne Moore, Khadidja Malloum Boukar, Pier-Alexandre Tardif, Henry T Stelfox, Howard Champion, Peter Cameron, Belinda Gabbe, Natalie Yanchar, John Kortbeek, François Lauzier, France Légaré, Patrick Archambault, Alexis F Turgeon
INTRODUCTION: Preventable injuries lead to 200 000 hospital stays, 60 000 disabilities, and 13 000 deaths per year in Canada with direct costs of $20 billion. Overall, potentially unnecessary medical interventions are estimated to consume up to 30% of healthcare resources and may expose patients to avoidable harm. However, little is known about overuse for acute injury care. We aim to identify low-value clinical practices in injury care. METHODS AND ANALYSIS: We will perform a scoping review of peer-reviewed and non-peer-reviewed literature to identify research articles, reviews, recommendations and guidelines that identify at least one low-value clinical practice specific to injury populations...
July 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28705361/changing-perceived-importance-of-religion-in-mainland-china-1990-2012-an-age-period-cohort-analysis
#19
Anning Hu
The comprehensive social reform and relaxation of religious regulation in mainland China have encouraged scholars to propose a revival thesis of religion, predicting a rising prevalence of religious adherence in the Reform Era. This study extends the revival thesis by focusing attention on people's subjective religiosity, and investigates age, period, and cohort effects on the transition in perceived importance of religion from 1990 to 2012. Capitalizing on the repeated cross-sectional data of the China sample in the World Values Survey, this study shows that (1) The senior population, relative to the younger counterpart, attaches greater importance to religion...
August 2017: Social Science Research
https://www.readbyqxmd.com/read/28703260/-publish-amp-perish-research-on-research-and-researchers
#20
J K Tijdink
In the last years many people have questioned the reliability of research results and the societal relevance of much of today's clinical research; they are critical too about the current publication culture in which scientists are judged according to the number of articles they have published, impact factors and citations.<br/> AIM: To make a close study of the publication culture that now prevails in the Dutch biomedical sciences. <br/> METHOD: Discussion of results described in the thesis entitled 'Publish and Perish; research on research and researchers'...
2017: Tijdschrift Voor Psychiatrie
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