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Jean Louis Trouillet, Olivier Collange, Fouad Belafia, François Blot, Gilles Capellier, Eric Cesareo, Jean-Michel Constantin, Alexandre Demoule, Jean-Luc Diehl, Pierre-Grégoire Guinot, Franck Jegoux, Erwan L'Her, Charles-Edouard Luyt, Yazine Mahjoub, Julien Mayaux, Hervé Quintard, François Ravat, Sebastien Vergez, Julien Amour, Max Guillot
Tracheotomy is widely used in intensive care units, albeit with great disparities between medical teams in terms of frequency and modality. Indications and techniques are, however, associated with variable levels of evidence based on inhomogeneous or even contradictory literature. Our aim was to conduct a systematic analysis of the published data in order to provide guidelines. We present herein recommendations for the use of tracheotomy in adult critically ill patients developed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) method...
March 15, 2018: Annals of Intensive Care
Mancino Raffaele, Massimo Cesareo, Alessio Martucci, Emiliano Di Carlo, Elena Ciuffoletti, Clarissa Giannini, Luigi Antonio Morrone, Carlo Nucci, Francesco Garaci
Recent literature agrees that neurodegenerative processes involve both the retina and the central nervous system, which are two strictly related anatomical structures. However, the causal mechanisms of this dual involvement are still uncertain. To date, anterograde transynaptic neurodegeneration, triggered by retinal ganglion cells' death, and retrograde transynaptic neurodegeneration, induced by neurodegenerative processes of the central nervous system, have been considered the major possible causal mechanisms...
March 6, 2018: Current Medicinal Chemistry
Irene Dominguez-Moñino, Valme Jurado, Jose L Gonzalez-Pimentel, Ana Zelia Miller, Bernardo Hermosin, Cesareo Saiz-Jimenez
Two Gram-positive, catalase-positive, oxidase-negative, motile, endospore-forming, rod-shaped bacteria, designated as 0911MAR22V3T and 0911TES10J4, were isolated from air samples collected in two show caves, located in Andalusia, Southern Spain. Phylogenetic analysis based on 16S rRNA gene sequences indicated that both strains were indistinguishable and they were most closely related to Bacillus humi DSM 16318T (98%). DNA-DNA hybridization values of the strain 0911MAR22V3T with respect to strain 0911TES10J4 and B...
January 25, 2018: Systematic and Applied Microbiology
Jose L Gonzalez-Pimentel, Ana Z Miller, Valme Jurado, Leonila Laiz, Manuel F C Pereira, Cesareo Saiz-Jimenez
Microbial diversity in lava tubes from Canary Islands (Spain) has never been explored thus far offering a unique opportunity to study subsurface microbiology. Abundant yellow coloured mats developing on coralloid speleothems in a lava tube from La Palma Islands were studied by next-generation sequencing and DNA/RNA clone library analyses for investigating both total and metabolically active bacteria. In addition, morphological and mineralogical characterization was performed by field emission scanning electron microscopy (FESEM), micro-computed tomography, X-ray diffraction and infrared spectroscopy to contextualize sequence data...
January 31, 2018: Scientific Reports
R Cesareo, A M Naciu, M Iozzino, V Pasqualini, C Simeoni, A Casini, G Campagna, S Manfrini, G Tabacco, A Palermo
CONTEXT: No defined pretreatment factors are able to predict the response to radiofrequency ablation(RFA) of an autonomously functioning thyroid nodule(AFTN). OBJECTIVE: primary endpoint was to evaluate the success rate of RFA to restore euthyroidism in a cohort of adult patients with small solitary AFTN compared with medium-sized nodules. Secondary endpoints included nodule volume reduction and rate of conversion from hot nodules to cold using scintiscan. METHODS: This was a 24-month prospective monocentric open parallel-group trial...
January 22, 2018: International Journal of Hyperthermia
Andrea Palermo, Marco Fosca, Gaia Tabacco, Federico Marini, Valerio Graziani, Maria Carla Santarsia, Filippo Longo, Angelo Lauria, Roberto Cesareo, Isabella Giovannoni, Chiara Taffon, Massimiliano Rocchia, Silvia Manfrini, Pierfilippo Crucitti, Paolo Pozzilli, Anna Crescenzi, Julietta V Rau
Primary hyperparathyroidism is an endocrine disorder characterized by autonomous production of parathyroid hormone. Patients with the symptomatic disease should be referred for parathyroidectomy. However, the distinction between the pathological condition and the benign one is very challenging in the surgical setting; therefore, accurate recognition is important to ensure success during minimally invasive surgery. At present, all intraoperative techniques significantly increase surgical time and, consequently, cost...
January 2, 2018: Analytical Chemistry
Delphine Hugenschmitt, Alexandre Allonneau, Éric Cesareo, Pierre-Yves Gueugniaud, Hugues Lefort
In the past, death was a family and community affair, but today it is institutional and entrusted to healthcare personnel. Thanks to a questionnaire on their feelings about prehospitalisation deaths, the experience and training needs for healthcare personnel at a mobile emergency and intensive care service were analysed. The majority of these professionals had been confronted with difficulties when faced with prehospitalisation deaths. There is little understanding of religious rites, even though this is an important point in dealing with the situation...
December 2017: Soins; la Revue de Référence Infirmière
Raffaele Mancino, Alessio Martucci, Massimo Cesareo, Clarissa Giannini, Maria Tiziana Corasaniti, Giacinto Bagetta, Carlo Nucci
Open Angle Glaucoma is one of the leading causes of irreversible blindness worldwide. Elevated intraocular pressure is considered an important risk factor for glaucoma, however a subset of patients experience disease progression even in presence of normal intraocular pressure values. This implies that risk factors other than intraocular pressure are involved in the pathogenesis of glaucoma. A possible relationship between glaucoma and neurodegenerative diseases such as Alzheimer Disease has been suggested. In this regard, we have recently described a high prevalence of alterations typical of glaucoma, using Heidelberg Retinal Tomograph-3 (HRT-3), in a group of patients with Alzheimer Disease...
December 6, 2017: Current Neuropharmacology
Silvia I Briganti, Gianluigi Gaspa, Gaia Tabacco, Anda M Naciu, Roberto Cesareo, Silvia Manfrini, Andrea Palermo
In humans, irisin is produced mainly by skeletal muscle in response to physical activity. It has been demonstrated that irisin plays a pivotal role in inducing fat browning and regulating energy expenditure. New findings from various studies conducted in both animals and humans suggest that irisin can affect bone and glucose metabolism. In particular, irisin is able to increase bone cortical mass by stimulating the osteoblast pathways, and irisin levels are inversely correlated with the incidence of fragility fractures among postmenopausal women affected by osteoporosis...
November 20, 2017: Minerva Endocrinologica
Cesáreo Álvarez Rodríguez, Manuel José Vázquez Lima
No abstract text is available yet for this article.
February 2017: Emergencias: Revista de la Sociedad Española de Medicina de Emergencias
Ambra Cesareo, Stefano Gandolfi, Ilaria Pini, Emilia Biffi, Gianluigi Reni, Andrea Aliverti
This paper presents a device for breathing frequency assessment over the long period, based on low cost, wearable inertial units. Performances of the device were evaluated in static conditions on 9 healthy subjects and the estimated parameters were compared to those obtained with an already validated method (Optoelectronic Plethysmography). We obtained good correlation values (R(2)> 0.88) and low percentage errors (<;5%) for all the time-based parameters extracted.
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Caterina Piazza, Ambra Cesareo, Martina Caccia, Gianluigi Reni, Maria L Lorusso
The processing of auditory stimuli is essential for the correct perception of language and deficits in this ability are often related to the presence or development of language disorders. The motor imitation (e.g. tapping or beating) of rhythmic sequences can be a very sensitive correlate of deficits in auditory processing. Thus, the study of the tapping performance, with the investigation of both temporal and intensity information, might be very useful. The present work is aimed at the development and preliminary testing of a tapping device to be used for the imitation and/or the production of rhythmic sequences, allowing the recording of both tapping duration and intensity...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
José Maria De la Rosa, Pedro M Martin-Sanchez, Santiago Sanchez-Cortes, Bernardo Hermosin, Heike Knicker, Cesareo Saiz-Jimenez
Two novel species of the fungal genus Ochroconis, O. lascauxensis and O. anomala have been isolated from the walls of the Lascaux Cave, France. The interest in these fungi and their melanins lies in the formation of black stains on the walls and rock art which threatens the integrity of the paintings. Here we report solid-state cross polarization magic-angle spinning (13)C and (15)N nuclear magnetic resonance (NMR) spectroscopy and surface-enhanced Raman spectroscopy (SERS) of the melanins extracted from the mycelia of O...
October 18, 2017: Scientific Reports
Pedro González, José Thenier, Raúl Galárraga, Adolfo de la Lama, Eva Azevedo, Cesáreo Conde
OBJECTIVES: It is common to observe the persistence of extra-axial collections after craniotomies. Most of these disappear in weeks or months but some remain. The onset of focal symptoms or the growth of these persistent collections months or years after surgery may indicate the presence of a chronic and latent infection by germs of low virulence such as Propionibacterium acnes (P. acnes). METHODS: We present two clinical cases with persistent extra-axial collections, which required surgery years after diagnosis, in which P...
October 13, 2017: Neurocirugía
Cesáreo Trueba Vasavilbaso, Carlos David Rosas Bello, Erla Medina López, Maria Pilar Coronel Granado, José Mario Navarrete Álvarez, Cesáreo Angel Trueba Davalillo, Félix Isaac Gil Orbezo
PURPOSE: To assess the effectiveness of viscosupplementation or platelet-rich plasma (PRP), compared to standard care, for pain relief after knee arthroscopic debridement in patients with meniscal pathology and osteoarthritis (OA), under normal clinical practice conditions. PATIENTS AND METHODS: We conducted a prospective, randomized, evaluator-blind, pilot study. After arthroscopy, patients were randomized to receive 1) five injections of HA1 (Suprahyal®/Adant®); 2) four injections of HA2 (Orthovisc®); 3) three injections of HA3 (Synvisc®); 4) a single injection of PRP (GPS™ II); or 5) standard care (control)...
2017: Open Access Rheumatology: Research and Reviews
Lili M Sardiñas, Viviana Padilla, Mari Aponte, Ana Morales Boscio, Coralee Pérez Pedrogo, Betzaida Santiago, Ángela Pérez Morales, Paloma Torres Dávila, Marizaida Sánchez Cesáreo
There are more people in the world in the youth stage of development than in any other stage of development. The youth in Puerto Rico faces many situations that affect their development and readiness for adulthood. Therefore, it's imperative to identify evidence-based positive youth development interventions to develop practices that help young people prevent adverse situations, promote positive experiences and encourage children and young people to be involved and committed. One hundred and forty seven interventions were identified through a traditional scientific literature review...
January 2017: Revista Puertorriqueña de Psicología
Roberto Cesareo, Andrea Palermo, Valerio Pasqualini, Roberto Cianni, Gianluigi Gaspa, Silvia Manfrini, Claudio Maurizio Pacella
The majority of benign thyroid nodules are asymptomatic, remain stable in size and do not require treatment. However, a minority of patients with growing nodules may have local symptoms or cosmetic concerns, and thus demand surgical therapy. The timely use of ultrasound-guided, minimally invasive thermal therapies has changed the natural history of benign, enlarging thyroid nodules (TNs). These procedures produce persistent shrinkage of TNs and an improvement of local symptoms. Among the various procedures, percutaneous ethanol injection represents the first-line treatment for thyroid cysts, while in solid cold nodules, laser and radiofrequency ablation (RFA) have proven to be very effective and safe techniques in producing significant volume reduction that remains stable over several years...
December 2017: Clinical Endocrinology
Montserrat Lázaro Del Nogal, Cesareo Férnandez, Paloma Serrano, Andrés Santiago, Patricia Villavicencio, Teresa Martin
OBJECTIVES: The Hospital Clínico San Carlos Committee against violence established a protocol in 2012 in order to detect and follow-up violence against elderly persons. This article presents the experience after 3years of its introduction, as well as an analysis comparing the differences between those younger and older than 65years of age. MATERIAL AND METHODS: All cases were collected during years 2013, 2014, and 2015, and were divided into two groups, A and B, according to age, younger or older than 65years...
June 27, 2017: Revista Española de Geriatría y Gerontología
J-S David, E-J Voiglio, E Cesareo, O Vassal, E Decullier, P-Y Gueugniaud, S Peyrefitte, K Tazarourte
BACKGROUND: This study aimed to evaluate the accuracy of prehospital parameters, including vital signs and resuscitation (fluids, vasopressor), to predict trauma-induced coagulopathy (TIC, fibrinogen <1·5 g/l or PTratio > 1·5 or platelet count <100 × 109 /l), and a massive transfusion (MT, ≥10 RBC units within the first 24 h). METHODS: From a trauma registry (2011-2015), in which patients are prospectively included, we retrospectively retrieved the heart rate (HR), systolic blood pressure (SBP), volume of prehospital fluids and administration of noradrenaline...
August 2017: Vox Sanguinis
Cesáreo Fernández Alonso, Juan Mariano Aguilar Mulet, Rodolfo Romero Pareja, Arístides Rivas García, Manuel Enrique Fuentes Ferrer, Juan Jorge González Armengol
OBJECTIVE: To identify predictors of frequent attenders (HF) in Primary Health Care (PHC) centres in a sample of frequent attenders (HF) in Emergency Departments (ED). DESIGN: This was an observational, retrospective, multicentre cohort study. PARTICIPANTS: The HF patients were selected from patients seen in the ED between January 1 and December 31, 2013. Setting Patients were recruited from 17 public hospitals of the Community of Madrid, Spain...
June 10, 2017: Atencion Primaria
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