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https://www.readbyqxmd.com/read/28292581/-chronic-obstructive-pulmonary-disease-in-real-life-leonpoc-study
#1
Silvia García García, Luis Carazo Fernández, Javier Juan García, José Cesáreo Rilo Naveiro
OBJECTIVE: The purpose of this study was to evaluate different characteristics of COPD patients according to phenotypes and GOLD guidelines.according to GesEPOC phenotypes and GOLD 2011 ABCD guidelines and pharmacological treatment agreement. DESIGN: Cross-sectional survey. LOCATION: COPD patients aged 40-85 from León were randomly selected from Primary Care database, MEDORA. PARTICIPANTS: 5222 eligible COPD patients were collected from MEDORA database...
March 11, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/28254286/synchrotron-based-xrd-from-rat-bone-of-different-age-groups
#2
D V Rao, G E Gigante, R Cesareo, A Brunetti, N Schiavon, T Akatsuka, T Yuasa, T Takeda
Synchrotron-based XRD spectra from rat bone of different age groups (w, 56 w and 78w), lumber vertebra at early stages of bone formation, Calcium hydroxyapatite (HAp) [Ca10(PO4)6(OH)2] bone fill with varying composition (60% and 70%) and bone cream (35-48%), has been acquired with 15keV synchrotron X-rays. Experiments were performed at Desy, Hamburg, Germany, utilizing the Resonant and Diffraction beamline (P9), with 15keV X-rays (λ=0.82666 A(0)). Diffraction data were quantitatively analyzed using the Rietveld refinement approach, which allowed us to characterize the structure of these samples in their early stages...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28226000/efficacy-and-safety-of-a-single-radiofrequency-ablation-of-solid-benign-non-functioning-thyroid-nodules
#3
Roberto Cesareo, Andrea Palermo, Valerio Pasqualini, Carla Simeoni, Alessandro Casini, Giuseppe Pelle, Silvia Manfrini, Giuseppe Campagna, Roberto Cianni
Objective: The objective of our study is to evaluate the clinical outcomes and safety of radiofrequency thermal ablation (RFA) for benign thyroid nodules (BTNs) over a 1-year follow-up. Subjects and methods: This is a monocentric retrospective study. Forty-eight patients with solid, non-functioning BTNs were treated by RFA using a 17G internally cooled electrode. We categorized thyroid nodules as small (≤ 12 mL), medium (12 to 30 mL), or large (over 30 mL). BTNs volume reduction, thyroid function, cosmetic and compressive score changes and side effect evaluation at 6 and 12 months were evaluated...
February 13, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28123438/a-rare-and-severe-complication-following-thyroid-fine-needle-aspiration-retropharyngeal-cellulitis
#4
Roberto Cesareo, Anda Naciu, Antonio Barberi, Valerio Pasqualini, Giuseppe Pelle, Silvia Manfrini, Gaia Tabacco, Angelo Lauria Pantano, Giuseppe Campagna, Roberto Cianni, Andrea Palermo
INTRODUCTION: Fine needle aspiration (FNA) is the most accurate and cost-effective method for evaluating thyroid nodules. We have reported a rare complication related to the procedure: severe retropharyngeal cellulitis. CASE PRESENTATION: A thirty-five-year-old female was admitted to hospital with hoarseness, laryngeal stridor and dyspnea without fever that emerged about 3 days after a first diagnostic FNA. After the procedure, the patient felt her voice became hoarse and 1 day before presentation began to have dyspnea, without fever...
October 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28116417/an-immersive-virtual-reality-platform-to-enhance-walking-ability-of-children-with-acquired-brain-injuries
#5
Emilia Biffi, Elena Beretta, Ambra Cesareo, Cristina Maghini, Anna C Turconi, Gianluigi Reni, Sandra Strazzer
BACKGROUND: Acquired brain injury (ABI) may result in lifelong impairment of physical, cognitive, and psychosocial functions. Several rehabilitative treatments are often needed to support walking recovery, thus participants' engagement becomes a crucial aspect, especially when patients are children. In the last few years, traditional physiotherapy (PT) has been flanked by innovative technologies for rehabilitation in the fields of robotics and Virtual Reality (VR). Preliminary results have shown interesting perspectives in the use of a VR system, the GRAIL (Gait Real-time Analysis Interactive Lab), in improving walking abilities in a small group of children with ABI, although further insights are needed about its use as rehabilitative tool in the pediatric population...
January 24, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28077667/the-role-of-the-cerebellum-in-high-stages-of-motor-planning-hierarchy
#6
Luca Casartelli, Alessandra Federici, Ambra Cesareo, Emilia Biffi, Giulia Valtorta, Massimo Molteni, Luca Ronconi, Renato Borgatti
Motor planning is not a monolithic process, and distinct stages of motor planning are responsible for encoding different levels of abstractness. However, how these distinct components are mapped into different neural substrates remains an open question. We studied one of these high-level motor planning components, defined as second-order motor planning, in a patient (R.G.) with an extremely rare case of cerebellar agenesis but without any other cortical malformations. Second-order motor planning dictates that when two acts have to be performed sequentially, planning of the second act can influence the execution of the first...
January 11, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/27904882/first-case-of-actinomycetoma-in-france-due-to-a-novel-nocardia-species-nocardia-boironii-sp-nov
#7
Jacques M Gilquin, Brigitte Riviere, Valme Jurado, Bernard Audouy, Jean-Baptiste Kouatche, Emmanuelle Bergeron, Delphine Mouniée, Thierry Molina, Philippe Faure, Cesáreo Saiz-Jimenez, Verónica Rodríguez-Nava
Bacterial mycetoma is a neglected disease mainly observed in tropical area countries and typically associated with rural conditions, making its presence in developed countries of temperate climate areas rare. However, we report the first case of an autochthonous mycetoma case in continental France that originated from a new Nocardia species. A Gram-positive filamentous bacterium (OFN 14.177(T)) was isolated from a pus sample from the mycetoma of a male French patient 92 years old suffering from chronic lymphocytic leukemia...
November 2016: MSphere
https://www.readbyqxmd.com/read/27580930/predictors-of-morbidity-and-cleavage-plane-in-surgical-resection-of-pure-convexity-meningiomas-using-cerebrospinal-fluid-sensitive-image-subtraction-magnetic-resonance-imaging
#8
José Luis Thenier-Villa, Raúl Alejandro Galárraga Campoverde, Adolfo Ramón DE LA Lama Zaragoza, Cesáreo Conde Alonso
Meningiomas are the most common primary intracranial tumors. Since the adhesions in the plane of dissection are of interest in surgical planning, we suggest that digital image subtraction of FLAIR data from the T2 sequence of MRI may represent better the CSF spaces in the brain-tumor interface and may be a predictor of the intraoperative cleavage plane. From 2006 to 2016, 83 convexity meningiomas were resected in the Department of Neurosurgery of the University Hospital Complex of Vigo, an analysis of preoperative MRI was performed to assess peritumoral edema (PTE), tumor volume, among others; a digital subtraction of T2-FLAIR sequences was performed and analyzed in relationship to the cleavage plane described in the intraoperative report and postoperative neurological deficits...
January 15, 2017: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/27487560/correction-to-tetrahydroisoquinoline-derived-urea-and-2-5-diketopiperazine-derivatives-as-selective-antagonists-of-the-transient-receptor-potential-melastatin-8-trpm8-channel-receptor-and-antiprostate-cancer-agents
#9
Luciano De Petrocellis, Francisco J Arroyo, Pierangelo Orlando, Aniello Schiano Moriello, Rosa Maria Vitale, Pietro Amodeo, Aránzazu Sánchez, Cesáreo Roncero, Giulia Bianchini, M Antonia Martín, Pilar López-Alvarado, J Carlos Menéndez
No abstract text is available yet for this article.
August 25, 2016: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/27452992/analytical-pyrolysis-and-stable-isotope-analyses-reveal-past-environmental-changes-in-coralloid-speleothems-from-easter-island-chile
#10
Ana Z Miller, José M De la Rosa, Nicasio T Jiménez-Morillo, Manuel F C Pereira, José A González-Pérez, José M Calaforra, Cesareo Saiz-Jimenez
This study comprises an innovative approach based on the combination of chromatography (analytical pyrolysis and pyrolysis compound-specific isotope analysis (Py-CSIA)), light stable isotopes, microscopy and mineralogy analyses to characterize the internal layering of coralloid speleothems from the Ana Heva lava tube in Easter Island (Chile). This multidisciplinary proxy showed that the speleothems consist of banded siliceous materials of low crystallinity with different mineralogical compositions and a significant contribution of organic carbon...
August 26, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27232526/tetrahydroisoquinoline-derived-urea-and-2-5-diketopiperazine-derivatives-as-selective-antagonists-of-the-transient-receptor-potential-melastatin-8-trpm8-channel-receptor-and-antiprostate-cancer-agents
#11
Luciano De Petrocellis, Francisco J Arroyo, Pierangelo Orlando, Aniello Schiano Moriello, Rosa Maria Vitale, Pietro Amodeo, Aránzazu Sánchez, Cesáreo Roncero, Giulia Bianchini, M Antonia Martín, Pilar López-Alvarado, J Carlos Menéndez
Tetrahydroisoquinoline derivatives containing embedded urea functions were identified as selective TRPM8 channel receptor antagonists. Structure-activity relationships were investigated, with the following conclusions: (a) The urea function and the tetrahydroisoquinoline system are necessary for activity. (b) Bis(1-aryl-6,7dimethoxy-1,2,3,4-tetrahydroisoquinolyl)ureas are more active than compounds containing one tetrahydroisoquinoline ring and than an open phenetylamine ureide. (c) Trans compounds are more active than their cis isomers...
June 23, 2016: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/27175804/effects-of-a-multidisciplinary-body-weight-reduction-program-on-static-and-dynamic-thoraco-abdominal-volumes-in-obese-adolescents
#12
Antonella LoMauro, Ambra Cesareo, Fiorenza Agosti, Gabriella Tringali, Desy Salvadego, Bruno Grassi, Alessandro Sartorio, Andrea Aliverti
The objective of this study was to characterize static and dynamic thoraco-abdominal volumes in obese adolescents and to test the effects of a 3-week multidisciplinary body weight reduction program (MBWRP), entailing an energy-restricted diet, psychological and nutritional counseling, aerobic physical activity, and respiratory muscle endurance training (RMET), on these parameters. Total chest wall (VCW), pulmonary rib cage (VRC,p), abdominal rib cage (VRC,a), and abdominal (VAB) volumes were measured on 11 male adolescents (Tanner stage: 3-5; BMI standard deviation score: >2; age: 15...
June 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/27133764/-hyperbilirubinemia-asymptomatic-as-presentation-of-autoimmune-hepatitis-in-an-elderly-patient
#13
Agustín Querejeta, Ana Isabel Hormigo-Sánchez, Cesáreo Fernández-Alonso, Francisco Javier Martín-Sánchez
No abstract text is available yet for this article.
November 2016: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/27111567/disparities-in-health-care-in-puerto-rico-compared-with-the-united-states
#14
Héctor M Colón, Marizaida Sánchez-Cesareo
No abstract text is available yet for this article.
June 1, 2016: JAMA Internal Medicine
https://www.readbyqxmd.com/read/26971128/paracoccus-cavernae-sp-nov-isolated-from-a-show-cave
#15
Irene Dominguez-Moñino, Valme Jurado, Bernardo Hermosin, Cesareo Saiz-Jimenez
A Gram-stain-negative, aerobic, non-motile, non-spore-forming bacterium, strain 0511ARD5E5T, was isolated from an air sample collected in Ardales Cave (Malaga, Spain). Strain 0511ARD5E5T grew at 4-37 °C and in the presence of 0-4 % (w/v) NaCl [optimally at 25 °C and with 1 % (w/v) NaCl]. Cells were catalase- and oxidase-positive. The major respiratory quinone was ubiquinone-10. The predominant fatty acids were C18:1ω7c and C16:0. The DNA G+C content was 63.2 mol%. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain 0511ARD5E5T was a member of the genus Paracoccus and was related most closely to Paracoccus aminophilus DSM 8538T and Paracoccus marinus CIP 108500T (96...
June 2016: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/26969462/italian-association-of-clinical-endocrinologists-ame-position-statement-drug-therapy-of-osteoporosis
#16
F Vescini, R Attanasio, A Balestrieri, F Bandeira, S Bonadonna, V Camozzi, S Cassibba, R Cesareo, I Chiodini, C Maria Francucci, L Gianotti, F Grimaldi, R Guglielmi, B Madeo, C Marcocci, A Palermo, A Scillitani, E Vignali, V Rochira, M Zini
Treatment of osteoporosis is aimed to prevent fragility fractures and to stabilize or increase bone mineral density. Several drugs with different efficacy and safety profiles are available. The long-term therapeutic strategy should be planned, and the initial treatment should be selected according to the individual site-specific fracture risk and the need to give the maximal protection when the fracture risk is highest (i.e. in the late life). The present consensus focused on the strategies for the treatment of postmenopausal osteoporosis taking into consideration all the drugs available for this purpose...
July 2016: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/26940993/rsk3-is-required-for-concentric-myocyte-hypertrophy-in-an-activated-raf1-model-for-noonan-syndrome
#17
Catherine L Passariello, Eliana C Martinez, Hrishikesh Thakur, Maria Cesareo, Jinliang Li, Michael S Kapiloff
Noonan syndrome (NS) is a congenital disorder resulting from mutations of the Ras-Raf signaling pathway. Hypertrophic cardiomyopathy associated with RAF1 "RASopathy" mutations is a major risk factor for heart failure and death in NS and has been attributed to activation of MEK1/2-ERK1/2 mitogen-activated protein kinases. We recently discovered that type 3 p90 ribosomal S6 kinase (RSK3) is an ERK effector that is required, like ERK1/2, for concentric myocyte hypertrophy in response to pathological stress such as pressure overload...
April 2016: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/26916908/-clinical-profile-and-90-day-mortality-in-centenarian-patients-attended-in-emergency-departments
#18
Francisco Javier Martín-Sánchez, Cesáreo Fernández-Alonso, Ana Isabel Hormigo, Gregorio Jiménez-Díaz, Honan Roiz, Cristina Bermejo-Boixareu, Jaime Rodríguez-Salazar, Cristina Fernández Pérez, Pedro Gil-Gregorio
OBJECTIVES: To determine the clinical profile and to develop a model to predict 90-day mortality in centenarian patients attended in emergency departments (ED). METHODOLOGY: This was an observational, retrospective, multicentre cohort study including patients >99years attended in 5 ED in the Community of Madrid from January to December 2012. Demographic variables were recorded, as well as, comorbidities, cognitive, functional, social basal status, geriatric syndromes, acute episode, and hospital and social resources use, and 90-day mortality...
July 2016: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/26733792/association-between-alzheimer-s-disease-and-glaucoma-a-study-based-on-heidelberg-retinal-tomography-and-frequency-doubling-technology-perimetry
#19
Massimo Cesareo, Alessio Martucci, Elena Ciuffoletti, Raffaele Mancino, Angelica Cerulli, Roberto P Sorge, Alessandro Martorana, Giuseppe Sancesario, Carlo Nucci
AIM: To assess the frequency of glaucoma-like alterations in Alzheimer's disease (AD) patients using Heidelberg Retinal Tomograph III (HRT-3) and Frequency Doubling Technology (FDT) perimetry. METHODS: The study included 51 eyes of 51 AD subjects and 67 eyes of 67 age- and sex-matched controls. Subjects underwent an ophthalmological examination including measurements of intraocular pressure (IOP), Matrix FDT visual field testing, optic nerve head morphology and retinal nerve fiber layer thickness (RNFLt) assessment by slit-lamp biomicroscopy and HRT-3...
2015: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/26696966/actinobacterial-diversity-in-volcanic-caves-and-associated-geomicrobiological-interactions
#20
Cristina Riquelme, Jennifer J Marshall Hathaway, Maria de L N Enes Dapkevicius, Ana Z Miller, Ara Kooser, Diana E Northup, Valme Jurado, Octavio Fernandez, Cesareo Saiz-Jimenez, Naowarat Cheeptham
Volcanic caves are filled with colorful microbial mats on the walls and ceilings. These volcanic caves are found worldwide, and studies are finding vast bacteria diversity within these caves. One group of bacteria that can be abundant in volcanic caves, as well as other caves, is Actinobacteria. As Actinobacteria are valued for their ability to produce a variety of secondary metabolites, rare and novel Actinobacteria are being sought in underexplored environments. The abundance of novel Actinobacteria in volcanic caves makes this environment an excellent location to study these bacteria...
2015: Frontiers in Microbiology
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