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https://www.readbyqxmd.com/read/28230603/computed-tomography-evaluation-of-nasal-bone-and-nasal-pyramid-in-the-turkish-population
#1
Hatice Kaplanoglu, Hüseyin Coskun, Ugur Toprak
OBJECTIVE: To classify shapes of the nasal bones in the Turkish population and comparatively evaluate the sizes of nasal bone and piriform apertures. METHODS: Two- and three-dimensional paranasal sinus computed tomography images of 363 patients were evaluated. Upper, intermediate, and inferior thickness of bilateral nasal bones and thickness of medial and lateral osteotomy line were measured. The shapes of the nasal bones were classified. RESULTS: The mean thickness of nasal bone in the study participants was 1...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28226320/impaired-pulmonary-function-in-patients-with-psoriasis
#2
Didem Didar Balci, Ebru Celik, Sebahat Genc, Muhammet Murat Çelik, Mehmet Ugur Inan
BACKGROUND: Psoriasis is associated with chronic obstructive pulmonary disease. There is no study on the spirometric pulmonary function testing in patients with psoriasis. OBJECTIVE: The aim of this study was to compare the spirometric parameters in patients with psoriasis and controls. METHODS: Ninety-six patients with psoriasis and 60 sex- and age-matched control subjects were included in this study. Spirometric pulmonary function testing, including percent forced vital capacity (FVC%), percent forced expiratory volume in the 1st second (FEV1%), forced expiratory flow at 25-75% of FVC (FEF25-75%), and FEV1/FVC ratio, was performed in all study subjects...
February 23, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/28215855/cloning-and-expression-of-cry2aa-from-native-bacillus-thuringiensis-strain-sy49-1-and-its-insecticidal-activity-against-culex-pipiens-diptera-culicidae
#3
Semih Yilmaz, Ugur Azizoglu, Abdurrahman Ayvaz, Ridvan Temizgul, Zehra Büşra Atciyurt, Salih Karabörklü
Bacillus thuringiensis (Berliner) (Bt) is well known for having toxicity against pest insects because of their ability to form endospores and broad-range activity of their parasporal inclusions. In this study, a new member of cry2A gene from previously characterized native B. thuringiensis SY49-1 strain was cloned, expressed and used for its activity against Culex pipiens (Diptera: Culicidae) larvae. The sequence analysis of the cloned cry2A gene revealed that it encodes a polypeptide of 633 aa residues with 99% identity to Cry2Aa protein with expected molecular weight of 70...
February 13, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28214780/distress-intolerance-in-the-parents-of-substance-dependent-patients
#4
Suat Ekinci, Hanife Uğur Kural
The purpose of this study was to determine levels of Distress Tolerance (DT) and to compare levels of DT, depression, and anxiety in the parents of substance dependent patients. This sample included 40 parents of inpatients undergoing treatment for substance dependence (SDPP) in the Balıklı Rum Hospital, Istanbul, Turkey. A healthy control group was recruited of 40 individuals with no Axis I diagnoses that were counterbalanced with the SDPP group in terms of age and sex. All study participants completed a sociodemographic data form and the Beck Depression Inventory, the Beck Anxiety Inventory, the State & Trait Anxiety Inventory, and the Distress Tolerance Scale...
December 24, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/28214048/psychosocial-and-behavioral-functioning-and-their-relationship-to-seizure-timing-in-children-with-benign-epilepsy-with-centrotemporal-spikes
#5
Gonca Bektaş, Uğur Tekin, Edibe Pembegül Yıldız, Tuğçe Aksu Uzunhan, Burak Tatlı, Nur Aydınlı, Mine Çalışkan, Meral Özmen
BACKGROUND: Psychosocial and behavioral problems have been reported in children with benign epilepsy with centrotemporal spikes (BECTS). Distinctive features of typical BECTS associated with cognitive and behavioral problems have not clearly been defined. PURPOSE: We aimed to identify psychosocial and behavioral functioning and their relationship to seizure timing in BECTS. METHODS: Consecutive patients with BECTS were recruited from the pediatric neurology outpatient clinic between May 2015 and May 2016...
February 14, 2017: Brain & Development
https://www.readbyqxmd.com/read/28213234/dna-wrapped-multi-walled-carbon-nanotube-modified-electrochemical-biosensor-for-the-detection-of-escherichia-coli-from-real-samples
#6
Dilsat Ozkan-Ariksoysal, Yasin Ugur Kayran, Fethiye Ferda Yilmaz, Anton Alexandru Ciucu, Iulia Gabriela David, Vasile David, Mine Hosgor-Limoncu, Mehmet Ozsoz
This paper introduces DNA-wrapped multi-walled carbon nanotube (MWCNT)-modified genosensor for the detection of Escherichia coli (E. coli) from polymerase chain reaction (PCR)-amplified real samples while Staphylococcus aureus (S. aureus) was used to investigate the selectivity of the biosensor. The capture probe specifically recognizing E. coli DNA and it was firstly interacted with MWCNTs for wrapping of single-stranded DNA (ssDNA) onto the nanomaterial. DNA-wrapped MWCNTs were then immobilised on the surface of disposable pencil graphite electrode (PGE) for the detection of DNA hybridization...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28198989/the-effects-of-health-education-given-by-nurses-to-copd-patients-on-the-daily-oxygen-concentrator-usage-time
#7
Uğur Doğan, Nimet Ovayolu
INTRODUCTION: Long-term oxygen therapy is the most effective method which has been shown to prolong the lifespan in people with COPD. The aim of the study was to investigate the effects of health education given by nurses to patients with COPD on the daily oxygen concentrator (OC) usage time. MATERIAL AND METHODS: The study was carried out in a State Hospital, Turkey, between July and November 2015. After given consent to the study, participants were divided into intervention and control groups by simple random sampling method...
2017: Adv Respir Med
https://www.readbyqxmd.com/read/28198784/choroidal-thickness-in-patients-with-stargardt-disease
#8
Esra Vural, Ugur Acar, Mehmet K Sevinc, Mesut Erdurmus, Bekir Kucuk, Seckin Aykas, Gungor Sobaci
PURPOSE: To investigate the relationship between choroidal thicknesses (CT), central foveal thicknesses, multifocal electroretinography (mf-ERG) responses, and best-corrected visual acuity levels in patients with Stargardt disease (STGD). METHODS: A total of 30 eyes of 30 patients with STGD, and 30 age- and sex-matched healthy controls were included in the study. All participants underwent detailed ophthalmic examination including best-corrected visual acuity and spectral domain optical coherence tomography measurements, and also patients with STGD were performed mf-ERG...
February 14, 2017: Retina
https://www.readbyqxmd.com/read/28198367/usp9x-regulates-ets-1-ubiquitination-and-stability-to-control-nras-expression-and-tumorigenicity-in-melanoma
#9
Harish Potu, Luke F Peterson, Malathi Kandarpa, Anupama Pal, Hanshi Sun, Alison Durham, Paul W Harms, Peter C Hollenhorst, Ugur Eskiocak, Moshe Talpaz, Nicholas J Donato
ETS transcription factors are commonly deregulated in cancer by chromosomal translocation, overexpression or post-translational modification to induce gene expression programs essential in tumorigenicity. Targeted destruction of these proteins may have therapeutic impact. Here we report that Ets-1 destruction is regulated by the deubiquitinating enzyme, Usp9x, and has major impact on the tumorigenic program of metastatic melanoma. Ets-1 deubiquitination blocks its proteasomal destruction and enhances tumorigenicity, which could be reversed by Usp9x knockdown or inhibition...
February 15, 2017: Nature Communications
https://www.readbyqxmd.com/read/28197814/choroidal-thickness-changes-determined-by-edi-oct-on-acute-anterior-uveitis-in-patients-with-hla-b27-positive-ankylosing-spondylitis
#10
Berna Basarir, Ugur Celik, Cigdem Altan, Nimet Burcu Celik
PURPOSE: To evaluate the choroidal thickness on acute anterior uveitis in patients with HLA-B27-positive ankylosing spondylitis. METHODS: In this study, 32 eyes of 16 HLA-B27 positive AS patients with anterior uveitis and age-matched 19 eyes for control group were analyzed between January 2014 and April 2015. Assessment criteria were uveitis activity, visual acuity, flare existence, subfoveal choroidal thickness and central macular thickness measurements. RESULTS: The mean subfoveal choroidal thicknesses in affected eye group (Group 1), unaffected eye group (Group 2) and control group (Group 3) were 348...
February 14, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28192868/value-of-vaginal-cervical-position-in-estimating-uterine-anatomy
#11
Ulaş Fidan, Uğur Keskin, Mustafa Ulubay, Mustafa Öztürk, Serkan Bodur
INTRODUCTION: The anatomy of the uterus is defined with the angles of the vagina, cervix and uterine corpus. Hereunder there are angles of version and flexion. The cervical position observed during the vaginal speculum examination, may give information about the uterine anatomy. MATERIAL AND METHODS: In this study, we investigated the place of the cervical position in the estimation of the uterine anatomy observed during the cervical examination. We enrolled 240 patients in our study, who applied to our routine gynecology outpatient clinic with various complaints...
February 13, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28191624/xanthomatous-meningioma-a-case-report
#12
Safak Ersoz, Zeynep Sagnak Yilmaz, İlker Eyüboglu, Ugur Yazar
Meningioma is a neoplasm derived from meningothelial cells. Grade1 meningiomas consist 9 different subtypes. One of the rare subtypes is metaplastic meningioma. Metaplastic meningioma could be defined as ''xanthomatous meningioma'' in the presence of prevalent xanthomatous changes. A 32 years old male patient had admitted to outpatient clinics with complaints of vertigo and tinnitus. Magnetic resonance imaging revealed a large mass of 7.4 cm in the right frontal region with an extra axial localization. Resection material demonstrated a neoplasm composed of classic meningothelial meningioma areas accompanied with areas of xanthomatous changes, containing cells with clear, vacuolated cytoplasm...
December 27, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28184327/the-effects-of-monosodium-glutamate-and-tannic-acid-on-adult-rats
#13
Ibrahim Ugur Calis, Didem Turgut Cosan, Faruk Saydam, Umut Kerem Kolac, Ahu Soyocak, Hulyam Kurt, Hasan Veysi Gunes, Varol Sahinturk, Fezan Sahin Mutlu, Zeynep Ozdemir Koroglu, Irfan Degirmenci
BACKGROUND: Monosodium glutamate (MSG) is a widely-used flavor enhancer and stabilizer in ready-made or packaged foods. The excessive use of MSG has been shown to increase oxidative stress in different organ systems and causes glucose metabolism disorders, obesity, and coronary diseases. OBJECTIVES: In this study, the antioxidant activity of tannic acid was investigated experimentally with respect to its protective effects against overdosed MSG-induced oxidative stress in rats...
October 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28178311/an-integrative-study-on-the-impact-of-highly-differentially-methylated-genes-on-expression-and-cancer-etiology
#14
Bugra Ozer, Ugur Sezerman
DNA methylation is an important epigenetic phenomenon that plays a key role in the regulation of expression. Most of the studies on the topic of methylation's role in cancer mechanisms include analyses based on differential methylation, with the integration of expression information as supporting evidence. In the present study, we sought to identify methylation-driven patterns by also integrating protein-protein interaction information. We performed integrative analyses of DNA methylation, expression, SNP and copy number data on paired samples from six different cancer types...
2017: PloS One
https://www.readbyqxmd.com/read/28176423/effects-of-foot-massage-applied-2-different-methods-on-symptom-control-in-colorectal-cancer-patients-randomized-control-trial
#15
Neşe Uysal, Sevinç Kutlutürkan, Işıl Uğur
This randomized controlled clinical study aimed to determine the effect of 2 foot massage methods on symptom control in people with colorectal cancer who received chemoradiotherapy. Data were collected between June 16, 2015, and February 10, 2016, in the Department of Radiation Oncology of an oncology training and research hospital. The sample comprised 60 participants. Data were collected using an introductory information form, common terminology criteria for adverse events and European Organization for Research and Treatment of Cancer Quality of Life Questionnaires C30 and CR29...
February 7, 2017: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/28167677/computational-approaches-for-de-novo-design-and-re-design-of-metal-binding-sites-on-proteins
#16
Osman Ugur Sezerman, Gunseli Bayram Akcapinar
Metal ions play pivotal roles for protein structure, function and stability. The functional and structural diversity of proteins in nature expanded with the incorporation of metal ions or clusters in proteins. Approximately one-third of these proteins in the databases contain metal ions.  Many biological and chemical processes in nature involve metal ion binding proteins, aka metalloproteins. Many cellular reactions that underpin life require metalloproteins. Most of the remarkable, complex chemical transformations are catalyzed by metalloenzymes...
February 6, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28158215/in-silico-analyses-and-global-transcriptional-profiling-reveal-novel-putative-targets-for-pea3-transcription-factor-related-to-its-function-in-neurons
#17
Başak Kandemir, Ugur Dag, Burcu Bakir Gungor, İlknur Melis Durasi, Burcu Erdogan, Eray Sahin, Ugur Sezerman, Isil Aksan Kurnaz
Pea3 transcription factor belongs to the PEA3 subfamily within the ETS domain transcription factor superfamily, and has been largely studied in relation to its role in breast cancer metastasis. Nonetheless, Pea3 plays a role not only in breast tumor, but also in other tissues with branching morphogenesis, including kidneys, blood vasculature, bronchi and the developing nervous system. Identification of Pea3 target promoters in these systems are important for a thorough understanding of how Pea3 functions. Present study particularly focuses on the identification of novel neuronal targets of Pea3 in a combinatorial approach, through curation, computational analysis and microarray studies in a neuronal model system, SH-SY5Y neuroblastoma cells...
2017: PloS One
https://www.readbyqxmd.com/read/28153633/comparison-of-the-presence-of-fragmented-qrs-complexes-in-the-inferior-versus-the-anterior-leads-for-predicting-coronary-artery-disease-severity
#18
Mehmet Eyuboglu, Ugur Kucuk, Omer Senarslan, Bahri Akdeniz
INTRODUCTION: Fragmented QRS complexes (fQRS) are a sign of myocardial scar and are associated with adverse outcomes and mortality in patients with coronary artery disease (CAD). However, little is known about the significance of fQRS or of their localization on electrocardiography (ECG) in patients without known CAD. We aimed to investigate the association between localization of fQRS on ECG and CAD severity in patients undergoing a first diagnostic coronary angiography. METHODS: We enrolled 135 consecutive patients who had a narrow fQRS on ECG and underwent a first diagnostic coronary angiography...
February 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/28144149/can-achilles-tendon-be-used-as-a-new-distal-landmark-for-coronal-tibial-component-alignment-in-total-knee-replacement-surgery-an-observational-mri-study
#19
Uğur Tiftikçi, Sancar Serbest, Veysel Burulday
BACKGROUND: In total knee arthroplasty, it is better to use more than one reference point for correct alignment of the components. By measuring the distances of Achilles tendon (AT) and other conventional landmarks from the mechanical axis in magnetic resonance imaging (MRI) of the ankle, we aimed to demonstrate that, as a novel landmark which can help for correct alignment in the coronal plane, AT is a better option than other landmarks. MATERIALS AND METHODS: This retrospective study was done on 53 ankle MRIs that met the criteria for inclusion to the study among 158 ankle MRIs...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28139286/a-comparison-of-the-cyclic-fatigue-resistance-of-used-and-new-glide-path-files
#20
Taha Özyürek, Gülşah Uslu, Uğur İnan
INTRODUCTION: The purpose of this study was to compare the cyclic fatigue resistance of used and new ProGlider (Dentsply Maillefer, Ballaigues, Switzerland) and PathFile (Dentsply Maillefer) rotary glide path files. METHODS: Forty ProGlider and 40 PathFile #2 instruments were used in the present study. In group 1, 20 PathFile #2 files and, in group 2, 20 ProGlider files were used to prepare a total of 40 J-shaped transparent acrylic blocks. In group 3 (control group), 20 new PathFile files and, in group 4 (control group), 20 new ProGlider files were included...
January 27, 2017: Journal of Endodontics
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