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https://www.readbyqxmd.com/read/28637131/translation-cultural-adaptation-reliability-and-validity-of-the-turkish-version-of-the-penn-shoulder-score
#1
Zeynep Hazar Kanik, Gurkan Gunaydin, Omer Osman Pala, Ugur Sozlu, Zeynep Beyza Alkan, Seyit Citaker, Selda Basar, Ulunay Kanatli
PURPOSE: The purpose of this study is to translate the Penn Shoulder Score into Turkish and to establish its cultural adaptation, reliability, and validity in patients with shoulder dysfunctions. METHODS: The Penn Shoulder Score was translated and culturally adapted from English into Turkish. Subsequently, the Penn Shoulder Score, the Constant Score, the American Shoulder and Elbow Score, and the Western Ontario Rotator Cuff Index were completed by 97 patients with shoulder dysfunctions...
February 7, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28625764/genome-wide-identification-and-expression-profiling-of-eil-gene-family-in-woody-plant-representative-poplar-populus-trichocarpa
#2
Ertugrul Filiz, Recep Vatansever, Ibrahim Ilker Ozyigit, Mehmet Emin Uras, Ugur Sen, Naser A Anjum, Eduarda Pereira
This study aimed to improve current understanding on ethylene-insensitive 3-like (EIL) members, least explored in woody plants such as poplar (Populus trichocarpa Torr. & Grey). Herein, seven putative EIL members were identified in P. trichocarpa genome and were roughly annotated either as EIN3-like sequence associated with ethylene pathway or EIL3-like sequences related with sulfur (S)-pathway. Motif-distribution pattern of proteins also corroborated this annotation. They were distributed on six chromosomes (chr1, 3, 4 and 8-10), and were revealed to encode a protein of 509-662 residues with nuclear localization...
June 15, 2017: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/28624849/the-accuracy-of-68-ga-psma-pet-ct-in-primary-lymph-node-staging-in-high-risk-prostate-cancer
#3
Can Öbek, Tünkut Doğanca, Emre Demirci, Meltem Ocak, Ali Rıza Kural, Asıf Yıldırım, Uğur Yücetaş, Çetin Demirdağ, Sarper M Erdoğan, Levent Kabasakal
PURPOSE: To assess the diagnostic accuracy of (68)Ga-PSMA PET in predicting lymph node (LN) metastases in primary N staging in high-risk and very high-risk nonmetastatic prostate cancer in comparison with morphological imaging. METHODS: This was a multicentre trial of the Society of Urologic Oncology in Turkey in conjunction with the Nuclear Medicine Department of Cerrahpasa School of Medicine, Istanbul University. Patients were accrued from eight centres. Patients with high-risk and very high-risk disease scheduled to undergo surgical treatment with extended LN dissection between July 2014 and October 2015 were included...
June 18, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28618972/techniques-and-modifications-for-tmj-arthrocentesis-a-literature-review
#4
Mehmet Fatih Şentürk, Tayfun Yazıcı, Uğur Gülşen
OBJECTIVES: To discuss advantages and disadvantages of TMJ arthrocentesis techniques, identifying modifications as reported in the literature. METHODS: A PubMed web-based search was carried out, using the terms TMJ and arthrocentesis, to determine the scope of coverage in well-documented articles in English. RESULTS: Among 237 articles, 12 distinct techniques were described for TMJ arthrocentesis in 12 articles. Among 12 techniques, 5 were classified as double puncture arthrocentesis (DPA) and 7 as single puncture arthrocentesis (SPA)...
June 15, 2017: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/28618738/groin-and-thigh-reconstructions-with-pedicled-rectus-abdominis-myocutaneous-flaps
#5
Hakan Uzun, Ozan Bitik, Yahya Baltu, Mehmet Dadaci, Aycan Uğur Kayikçioğlu
BACKGROUND/AIM: Resection of tumors from the groin and thigh regions with safe margins often results in significant soft tissue defects, which preclude primary closure. This study presents a series of rectus abdominis myocutaneous flaps for irradiated thigh and groin wounds with the purpose of evaluating the efficacy and outcomes of these flaps in this population. MATERIALS AND METHODS: From 2008 to 2015, all patients who underwent resection of thigh or groin region tumors and reconstruction with an inferiorly based rectus abdominis myocutaneous flap were retrospectively identified...
June 12, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28609328/the-early-radiological-effects-of-dega-and-pemberton-osteotomies-on-hip-development-in-children-aged-4-8-years-with-developmental-dysplasia-of-the-hip
#6
Baran Sarikaya, Serkan Sipahioglu, Zeynep B Sarikaya, Celal Bozkurt, Mehmet A Altay, Ugur E Isikan
We aimed to investigate the early radiological effects of Dega and Pemberton iliac osteotomies that were performed in patients aged 4-8 years with developmental dysplasia of the hip on development of hip joint. Dega osteotomy or Pemberton osteotomy was performed in 76 hips of 58 patients because of developmental dysplasia of the hip between September 2011 and June 2015 and were evaluated retrospectively. Of a total of 76 hips, Pemberton osteotomy was performed on 39 (19 unilateral) and Dega osteotomy was performed on 37 (21 unilateral)...
June 12, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28608351/course-of-aggressive-somatotroph-corticotroph-and-mammotroph-tumors-under-temozolomide-report-of-three-cases-and-review-of-the-literature
#7
Berna İmge Aydoğan, Uğur Ünlütürk, Rıfat Emral, Sevim Güllü
Treatment of aggressive pituitary tumors may be challenging. Temozolomide (TMZ) is a promising agent when conventional treatment methods fail. We present three patients with aggressive pituitary tumors with atypical morphology, who were resistant to conventional treatments and treated with TMZ. First case had a somatotroph adenoma, second a corticotroph adenoma, and the third a macroprolactinoma. We also reviewed the literature reporting TMZ efficacy in somatotroph, corticotroph and mammotroph tumors of pituitary...
May 7, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28604701/elimination-of-large-tumors-in-mice-by-mrna-encoded-bispecific-antibodies
#8
Christiane R Stadler, Hayat Bähr-Mahmud, Leyla Celik, Bernhard Hebich, Alexandra S Roth, René P Roth, Katalin Karikó, Özlem Türeci, Ugur Sahin
The potential of bispecific T cell-engaging antibodies is hindered by manufacturing challenges and short serum half-life. We circumvented these limitations by treating mice with in vitro-transcribed pharmacologically optimized, nucleoside-modified mRNA encoding the antibody. We achieved sustained endogenous synthesis of the antibody, which eliminated advanced tumors as effectively as the corresponding purified bispecific antibody. Because manufacturing of pharmaceutical mRNA is fast, this approach could accelerate the clinical development of novel bispecific antibodies...
June 12, 2017: Nature Medicine
https://www.readbyqxmd.com/read/28599660/does-the-location-of-placement-of-meniscal-sutures-have-a-clinical-effect-in-the-all-inside-repair-of-meniscocapsular-tears
#9
Uğur Tiftikçi, Sancar Serbest
BACKGROUND: Meniscocapsular separation (MCS) is a lesion of the area which is attached from the peripheral section of the meniscus to the capsule and is seen less often than other meniscus injuries. The aim of this study was to investigate which of the different side applications of all-inside MCS repair of the meniscus was better in respect of clinical and functional results. METHODS: In this retrospective study, 53 patients with MCS pattern in their knee joints were treated with arthroscopic meniscus repair made with the all-inside method...
June 9, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28597365/a-novel-pathogenic-frameshift-variant-of-cd3e-gene-in-two-t-b-nk-scid-patients-from-turkey
#10
Sinem Firtina, Yuk Yin Ng, Ozden Hatirnaz Ng, Serdar Nepesov, Osman Yesilbas, Meltem Kilercik, Nihan Burtecene, Suzan Cinar, Yildiz Camcioglu, Ugur Ozbek, Muge Sayitoglu
Severe combined immunodeficiency (SCID) is the most severe form of primary immunodeficiency, which is characterized by the dysfunction and/or absence of T lymphocytes. Early diagnosis of SCID is crucial for overall survival, and if it remains untreated, SCID is often fatal. Next-generation sequencing (NGS) has become a rapid, high-throughput technology, and has already been proven to be beneficial in medical diagnostics. In this study, a targeted NGS panel was developed to identify the genetic variations of SCID by using SmartChip-TE technology, and a novel pathogenic frameshift variant was found in the CD3E gene...
June 9, 2017: Immunogenetics
https://www.readbyqxmd.com/read/28596511/effect-of-alprazolam-on-redox-status-in-renal-transplantation-donors-and-recipients
#11
Meltem Güner Can, Özgen Ilgaz Koçyiğit, Uğur Aksu, Ali Özer, Fevzi Toraman
BACKGROUND Benzodiazepines are the most popular premedication drugs thought to act through the GABA/benzodiazepine receptor complex and alprazolam is one of the most potent benzodiazepines that have a quick onset. While there is a growing body of evidence supporting alprazolam in the amelioration of redox status in animals, no study has been performed concerning its antioxidant activity in humans. The purpose of this investigation was to determine the effect of alprazolam on redox status. MATERIAL AND METHODS This study was a four-group randomized controlled trial...
June 9, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28589186/extremely-rare-presentation-of-an-omphalomesenteric-cyst-in-a-61-year-old-patient
#12
Recep Aktimur, Uğur Yaşar, Elif Çolak, Nuraydın Özlem
The umbilicus is remaining scar tissue from the umbilical cord in the fetus. If the omphalomesenteric duct in the umbilicus is not properly closed, an ileal-umbilical fistula, sinus formation, cysts, or, most commonly, Meckel's diverticulum can develop. The others are very rare and mostly occur in the pediatric population. We describe herein a 61-year-old female with a giant omphalomesenteric cyst presented as an asymptomatic infraumbilical mass. To our knowledge, this is the oldest patient reported and the largest cyst described in the literature...
2017: Turk J Surg
https://www.readbyqxmd.com/read/28585622/enantioselective-synthesis-of-pyrazolone-%C3%AE-aminonitrile-derivatives-via-an-organocatalytic-strecker-reaction
#13
Suruchi Mahajan, Pankaj Chauhan, Uğur Kaya, Kristina Deckers, Kari Rissanen, Dieter Enders
A new organocatalytic enantioselective Strecker reaction of pyrazolone-derived ketimine electrophiles has been developed. Using pseudo-enantiomeric squaramide catalysts the nucleophilic 1,2-addition of trimethylsilyl cyanide to the ketimines efficiently provides a direct entry to both enantiomers of pyrazolone α-aminonitrile derivatives at will in good yields and high enantioselectivities for a wide variety of substrates.
June 21, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28579791/color-m-mode-echocardiography-derived-propagation-velocity-of-descending-aorta-decreases-with-aging
#14
Mehmet Yaman, Uğur Arslan, Adil Bayramoğlu, Osman Bektaş, Ahmet Karataş
BACKGROUND: Arterial stiffness (AS) can be determined by some noninvasive tests such as pulse wave velocity (PWV). Atherosclerosis is also detectable by some ultrasonographic techniques such as color M-mode-derived propagation velocity measured along the origin of the descending aorta (AVP). AIM: The aim of the study was to find out a possible relationship between atherosclerosis and AVP and whether AVP can be used as a parameter of AS. MATERIALS AND METHODS: The study group was composed of 134 people from routine screening examination who were ≥40 years old, completely healthy, and without any known disease and use of any drug...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28575765/the-influence-of-levetiracetam-on-psychosocial-and-behavioral-functioning-in-children-a-case-control-and-follow-up-study
#15
Gonca Bektaş, Uğur Tekin, Melis Ulak Özkan, Edibe Pembegül Yıldız, Mine Çalışkan, Meral Özmen, Nur Aydınlı
BACKGROUND: Levetiracetam, a widely used antiepileptic drug in children, has been associated with psychosocial and behavioral problems, which are also influenced by epilepsy variables, including duration or seizure frequency. PURPOSE: The objective of this study is to investigate the frequency and timing of treatment-emergent psychosocial and behavioral problems in children receiving levetiracetam, irrespective of seizure variables which are possible confounders...
May 30, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28573968/arthroscopic-assisted-retrograde-mosaicplasty-for-an-osteochondral-defect-of-the-femoral-head-without-performing-surgical-hip-dislocation
#16
Onur Kocadal, Budak Akman, Melih Güven, Uğur Şaylı
Osteochondral autograft transplantation (mosaicplasty) for the osteochondral defects of the femoral head is generally performed with safe dislocation of the hip joint. Here, we present a 27-year-old male patient who had a symptomatic osteochondral defect of the femoral head and underwent mosaicplasty applied by hip arthroscopy without surgical hip dislocation. The preoperative radiological evaluation showed a focal osteochondral defect on the weight-bearing surface of the femoral head. With the assistance of hip arthroscopy, the defect area was reconstructed with osteochondral plug, which was taken from the ipsilateral knee, inserted in a retrograde fashion, and positioned with the spherical surface of the femoral head cartilage under fluoroscopic and arthroscopic control...
2017: SICOT-J
https://www.readbyqxmd.com/read/28572043/prelaminated-extended-temporoparietal-fascia-flap-without-tissue-expansion-for-hemifacial-reconstruction
#17
Muzaffer Altındaş, Hakan Arslan, Uğur Anıl Bingöl, Anıl Demiröz
BACKGROUND: Disfigurement of the face caused by postburn scars, resected congenital nevi and vascular malformations has both functional and psychological consequences. Ideal reconstruction of the facial components requires producing not only function but also the better appearance of the face. The skin of the neck, supraclavicular or cervicothoracic regions are the most commonly used and the most likely source of skin for facial reconstruction in those techniques which prefabrications with tissue expansion are used...
May 24, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28567312/intracorneal-hematoma-showing-clinical-and-dermoscopic-features-of-acral-lentiginous-melanoma
#18
Ugur Uslu, Franz Heppt, Michael Erdmann
Intra- and subcorneal hematoma, a skin alteration seen palmar and plantar after trauma or physical exercise, can be challenging to distinguish from in situ or invasive acral lentiginous melanoma. Thus, careful examination including dermoscopic and histologic assessment may be necessary to make the correct diagnosis. We here present a case of a 67-year-old healthy female patient who presented with a pigmented plantar skin alteration. Differential diagnoses included benign skin lesions, for example, hematoma or melanocytic nevus, and also acral lentiginous melanoma or melanoma in situ...
2017: Case Reports in Dermatological Medicine
https://www.readbyqxmd.com/read/28566960/efficacy-of-different-durations-of-intravenous-methylprednisolone-treatment-in-relapses-of-multiple-sclerosis
#19
Uğur Kulu, Bedile İrem Tiftikcioğlu, Yaşar Zorlu, Mustafa Çetiner, Ufuk Şener, Gamze Tuna, Güldal Kirkali
INTRODUCTION: Relapses of multiple sclerosis (MS) are usually treated with high-dose intravenous methylprednisolone (IVMP), given over 3-10 days. There is no consensus on the optimal duration of treatment. In this study, we aimed to investigate whether longer treatment provides additional short-term clinical benefits assessed by the change in plasma cytokine levels and EDSS scores in patients with relapsing-remitting MS (RRMS). METHODS: Forty RRMS patients during relapse were grouped into 3 and treated with 1 g/day of IVMP for either 5, 7, or 10 consecutive days...
March 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28559737/optimisation-of-microwave-assisted-extraction-of-pomegranate-punica-granatum-l-seed-oil-and-evaluation-%C3%A2-of-its-physicochemical-and-bioactive-properties
#20
Hasene Keskin Çavdar, Derya Koçak Yanık, Uğur Gök, Fahrettin Göğüş
Pomegranate seed oil was extracted in a closed-vessel high-pressure microwave system. The characteristics of the obtained oil, such as fatty acid composition, free fatty acidity, total phenolic content, antioxidant activity and colour, were compared to those of the oil obtained by cold solvent extraction. Response surface methodology was applied to optimise extraction conditions: power (176-300 W), time (5-20 min), particle size (d=0.125-0.800 mm) and solvent to sample ratio (2:1, 6:1 and 10:1, by mass). The predicted highest extraction yield (35...
March 2017: Food Technology and Biotechnology
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