Kendall H Lee, Su-Youne Chang, Dong-Pyo Jang, Inyong Kim, Stephan Goerss, Jamie Van Gompel, Paul Min, Kanika Arora, Michael Marsh, Sun Chul Hwang, Christopher J Kimble, Paul Garris, Charles Blaha, Kevin E Bennet
Deep brain stimulation (DBS) within the basal ganglia complex is an effective neurosurgical approach for treating symptoms of Parkinson's disease (PD), Essential Tremor, Dystonia, Depression, Obssessive Compulsive Disorder, and Tourette's Syndrome, among others. Elucidating DBS mechanism has become a critical clinical and research goal in stereotactic and functional neurosurgery and in neural engineering. Along with electro-physiological and microdialysis techniques, two additional powerful technologies, notably functional Magnetic Resonance Imaging (fMRI) and in vivo neurochemical monitoring have recently been used to investigate DBS-mediated activation of basal ganglia network circuitry...
2011: Annual International Conference of the IEEE Engineering in Medicine and Biology Society