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Hypodontia

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https://www.readbyqxmd.com/read/28091449/crouzon-syndrome-with-multiple-supernumerary-teeth
#1
G S Torun, A Akbulut
Crouzon syndrome (CS) is an autosomal dominant disorder characterized by craniofacial deformities caused by the early closure of cranial sutures. It is diagnosed by the presence of a flat sphenoid bone, protrusion of eyeballs (exophthalmos), and midfacial hypoplasia. Although hypodontia is usually present in cases with CS, supernumerary teeth are rarely seen. A 16-year-old male patient with CS was referred to our clinic. He had a high forehead, beaked nose, hypertelorism, palpebral ptosis, and asymmetrical orbits...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28040065/effects-of-pax9-and-msx1-gene-variants-to-hypodontia-tooth-size-and-the-type-of-congenitally-missing-teeth
#2
D Kirac, F Eraydin, T Avcilar, K Ulucan, F Özdemir, A I Guney, E Ç Kaspar, E Keshi, T Isbir
ooth agenesis, affecting up to 20% of human population, is one of the most common congenital disorder. The most frequent form of tooth agenesis is known as hypodontia, which is characterized by the absence of one to five permanent teeth excluding third molars. It was considered that hypodontia is especially related with gene mutations which play role in tooth formation. Additionally mutations in PAX9 and/or MSX1 have been identified as the defects responsible for missing permanent molars and second premolars...
November 30, 2016: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28027172/an-uncommon-occurrence-of-three-fourth-molars-concomitant-to-hypodontia-in-a-nonsyndromic-patient
#3
Ligia Buloto Schmitd, Agnes Assao, Gabriel Ramalho-Ferreira, Leonardo Perez Faverani, Denise Tostes Oliveira
Bilaterally mandibular and maxillary fourth molars, concomitant to hypodontia, are uncommon. These dental anomalies, called hypohyperdontia, are rare and etiology is not well defined. Several complications may occur as a consequence of supernumerary teeth, such as teeth impaction, resorption of adjacent teeth, and development of cysts and tumors. The authors present an uncommon occurrence of three-fourth molars concomitant to hypodontia and dentigerous cyst associated with impacted mandibular second and third molars in a nonsyndromic patient...
December 23, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27994418/a-retrospective-cross-sectional-study-on-the-prevalence-of-hypodontia-in-a-target-population-of-al-jouf-province-saudi-arabia
#4
Arbaz Sajjad, Samia Subhani Sajjad, Nadeem Husain, Ahmed Maashi Al-Enezi
AIM: The purpose of this retrospective study was to determine the prevalence of hypodontia and to ascertain the need of interdisciplinary treatment for ensuing esthetic and functional problems in a target population of Al-Jouf Province, Saudi Arabia. SUBJECTS AND METHODS: Using a dental administration software tool, a total of 1267 patients who presented to the outpatient clinics of the Orthodontic and Prosthodontic Departments between March 2015 and January 2016 were identified...
October 2016: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/27957258/prevalence-and-distribution-of-selected-dental-anomalies-among-saudi-children-in-abha-saudi-arabia
#5
Syed M Yassin
BACKGROUND: Dental anomalies are not an unusual finding in routine dental examination. The effect of dental anomalies can lead to functional, esthetic and occlusal problems. The Purpose of the study was to determine the prevalence and distribution of selected developmental dental anomalies in Saudi children. MATERIAL AND METHODS: The study was based on clinical examination and Panoramic radiographs of children who visited the Pediatric dentistry clinics at King Khalid University College of Dentistry, Saudi Arabia...
December 2016: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/27951410/non-syndromic-severe-hypodontia-caused-by-a-novel-frameshift-insertion-mutation-in-the-homeobox-of-the-msx1-gene
#6
Mushriq F Abid, M A Simpson, Christos Petridis, M T Cobourne, P T Sharpe
OBJECTIVE: Inherited congenital anomalies in tooth number, particularly hypodontia are relatively common. Although substantial progress has been made that permits a better understanding of the causes of tooth agenesis, overall knowledge of the phenotype:genotype correlations in this anomaly are still lacking. The aim in this study was to identify the causal gene mutation(s) in a family of two sisters with severe hypodontia (oligodontia) including 2nd premolars and 1st and 3rd molars, using whole exome sequencing (WES)...
December 6, 2016: Archives of Oral Biology
https://www.readbyqxmd.com/read/27933446/permanent-tooth-agenesis-in-non-syndromic-robin-sequence-and-cleft-palate-prevalence-and-patterns
#7
Anneline de Smalen, Daan P F van Nunen, Ruurd R Hermus, Edwin M Ongkosuwito, Arjen J van Wijk, J Peter W Don Griot, Corstiaan C Breugem, Gem J C Kramer
OBJECTIVES: Partial tooth agenesis is frequently observed in Robin sequence. Tooth anomalies are increasingly considered as an extended phenotype of the cleft palate population. The study objective was to compare the prevalence and patterns of tooth agenesis in a group of patients with non-syndromic Robin sequence (ns-RS) and a group with non-syndromic cleft palate (ns-CP). MATERIALS AND METHODS: The panoramic radiographs of 115 ns-RS and 191 ns-CP patients were assessed for agenesis of the permanent dentition (excluding third molars) and the patterns recorded using the Tooth Agenesis Code...
December 9, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27895972/genetic-basis-of-nonsyndromic-and-syndromic-tooth-agenesis
#8
REVIEW
Xiaoqian Ye, Ali B Attaie
Human dentition development is a long and complex process which involves a series of reciprocal and sequential interactions between the embryonic stomodeal epithelium and the underlying neural crest-derived mesenchyme. Despite environment disturbances, tooth development is predominantly genetically controlled. To date, more than 200 genes have been identified in tooth development. These genes implied in various signaling pathways such as the bone morphogenetic protein, fibroblast growth factor, sonic hedgehog homolog, ectodysplasin A, wingless-type MMTV integration site family (Wnt), and transform growth factor pathways...
December 2016: Journal of Pediatric Genetics
https://www.readbyqxmd.com/read/27895346/association-between-hypodontia-and-angles-malocclusion
#9
Batool Ali, Syed Sheeraz Hussain
This study was planned to determine the prevalence of hypodontia in permanent dentition and to test whether an association was present between hypodontia and Angle's malocclusion. The retrospective study was conducted at a tertiary care hospital, Karachi, and comprised record of all patients visiting the orthodontic clinics of the hospital from 2005 to 2015. Orthodontic records of 790(79%) subjects, including 189(23.9%) males and 601(76.1%) females, were reviewed. Their mean age was 17 ± 5.06 years. A tooth was considered missing if no evidence of tooth germ was observed on orthopantomograms and dental casts...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27874918/kooperation-von-kieferorthop%C3%A3-die-kieferchirurgie-und-prothetik-bei-der-umfassenden-rehabilitation-von-dysgnathiepatientinnen-teil-2-fallbeispiel-klasse-ii-malokklusion-tiefbiss-hypodontie
#10
Dagmar Schnabl, Martin Brock, Wolfgang Puelacher
Dental aplasia of heterogenous etiology may cause jaw growth disturbance, malocclusion, esthetic discontent and psychosocial impairment. By a case report of a young patient suffering from hypodontia, class II malocclusion and a deep bite the intricate interdisciplinary diagnosis- and treatment-protocol targeting the functional and esthetic rehabilitation is illustrated.
2016: Swiss Dental Journal
https://www.readbyqxmd.com/read/27860241/second-premolar-agenesis-as-a-subclinical-phenotype-of-isolated-cleft-palate
#11
J P Schwartz, R C M C Lauris, G Dalbén, D G Garib
OBJECTIVE: To compare the prevalence of dental anomalies in patients with isolated cleft palate with or without hypodontia of the second premolar. SETTING AND SAMPLE POPULATION: A total of 653 patients with isolated cleft palate aged 8-12 years were divided into two groups: G1-subjects without hypodontia of second premolar (n = 546) and G2-subjects with hypodontia of at least one-second premolar (n = 107). The control group consisted of 107 non-cleft orthodontic patients...
November 14, 2016: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/27812891/hypodontia-of-all-primary-canines
#12
R P Anthonappa, N M King
BACKGROUND: Several hypotheses have been proposed to explain hypodontia of the various tooth types with evolutionary and anatomic models. Hypodontia of all primary canines in a healthy individual is exceptionally rare and has not been previously reported in the dental literature. CASE REPORT: This clinical report describes a 4-year-old southern Chinese female with the congenital absence of the primary canines in all quadrants. Furthermore, all of the permanent tooth germs excluding the third molars were evident on a panoramic radiograph and were developing consistent with the subject's chronological age...
December 2016: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/27805878/evaluation-of-the-orthodontic-component-of-the-hypodontia-care-pathway
#13
Aliki Tsichlaki
No abstract text is available yet for this article.
December 2016: Journal of Orthodontics
https://www.readbyqxmd.com/read/27773763/development-of-a-measure-of-hypodontia-patients-expectations-of-the-process-and-outcome-of-combined-orthodontic-and-restorative-treatment
#14
Afnan Ben Gassem, Richard Foxton, Dirk Bister, Tim Newton
OBJECTIVES: To devise and assess the psychometric properties of a measure that investigates hypodontia patients' expectations of the process and outcome of combined orthodontic/restorative treatment. SETTING: Specialised secondary care facility for individuals with hypodontia. MATERIALS AND METHODS: Mixed research design with three phases: (a) Thematic analysis of data from individual interviews with 25 hypodontia patients/16 parents to generate the questionnaire items...
October 20, 2016: Journal of Dentistry
https://www.readbyqxmd.com/read/27767023/radiographic-study-of-the-prevalence-and-distribution-of-hypodontia-associated-with-unilateral-and-bilateral-clef-lip-and-palate-in-a-hungarian-population
#15
Ádám Berniczei-Roykó, Jan-Hendrik Tappe, Axel Krinner, Tomasz Gredes, András Végh, Katona Gábor, Kamila Linkowska-Świdzińska, Ute Ulrike Botzenhart
BACKGROUND Cleft defects are one of the most frequent birth-deformities of the orofacial region and they are commonly associated with anomalies of the tooth structure, size, shape, formation, eruption, and tooth number. The aim of our study was to evaluate the prevalence, distribution, and potential association of combined hypodontia in cleft-affected patients with regard to all types of teeth in both jaws in the permanent dentition. MATERIAL AND METHODS This retrospective radiographic analysis included patients with various types of clefts treated orthodontically in the Department of Orofacial Orthopedics and Orthodontics at Heim Pàl Children's Hospital, Budapest...
October 21, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27736875/mutations-in-tspear-encoding-a-regulator-of-notch-signaling-affect-tooth-and-hair-follicle-morphogenesis
#16
Alon Peled, Ofer Sarig, Liat Samuelov, Marta Bertolini, Limor Ziv, Daphna Weissglas-Volkov, Marina Eskin-Schwartz, Christopher A Adase, Natalia Malchin, Ron Bochner, Gilad Fainberg, Ilan Goldberg, Koji Sugawara, Avital Baniel, Daisuke Tsuruta, Chen Luxenburg, Noam Adir, Olivier Duverger, Maria Morasso, Stavit Shalev, Richard L Gallo, Noam Shomron, Ralf Paus, Eli Sprecher
Despite recent advances in our understanding of the pathogenesis of ectodermal dysplasias (EDs), the molecular basis of many of these disorders remains unknown. In the present study, we aimed at elucidating the genetic basis of a new form of ED featuring facial dysmorphism, scalp hypotrichosis and hypodontia. Using whole exome sequencing, we identified 2 frameshift and 2 missense mutations in TSPEAR segregating with the disease phenotype in 3 families. TSPEAR encodes the thrombospondin-type laminin G domain and EAR repeats (TSPEAR) protein, whose function is poorly understood...
October 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27733874/prevalence-of-dental-anomalies-in-permanent-dentition-of-brazilian-individuals-with-down-syndrome
#17
Osmar Aparecido Cuoghi, Francielle Topolski, Lorraine Perciliano de Faria, Carla Machado Occhiena, Nancy Dos Santos Pinto Ferreira, Camila Ribeiro Ferlin, Marcos Rogério de Mendonça
OBJECTIVE: The aim of this study was to evaluate the incidence of dental anomalies in the permanent dentition of individuals with Down Syndrome (DS) to increase the knowledge on the dental issues in this syndrome. METHOD: One hundred and five panoramic X-rays of patients with DS (61 males and 44 females), aged 7 to 42 years were used. The data were statistically analyzed using bivariate analyses test (p <0.05). RESULTS: Dental anomalies were observed in 50...
2016: Open Dentistry Journal
https://www.readbyqxmd.com/read/27730036/christ-siemens-touraine-syndrome-with-palmoplantar-keratoderma-a-rare-association
#18
Sunil K Kothiwala, Mahesh Prajapat, C M Kuldeep
Christ-Siemens-Touraine syndrome is a form of anhidrotic ectodermal dysplasia (ED) characterized by triad of hypodontia, hypotrichosis, and hypohidrosis. Palmoplantar keratoderma is a characteristic feature of hidrotic forms of ED. Till date, only two cases have been reported of Christ-Siemens-Touraine syndrome with palmoplantar keratoderma; here we report a similar case emphasizing this rare association.
September 2016: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/27702401/evaluation-of-the-orthodontic-component-of-the-hypodontia-care-pathway
#19
Mary O'Keeffe, Joanne M Collins, Susan J Cunningham
INTRODUCTION: This study evaluated patients' experiences of the Hypodontia Care Pathway at a large teaching hospital at key stages: specifically patient expectations/experience following the diagnosis of hypodontia and then patient satisfaction with the orthodontic care received and the outcome at the end of active orthodontic treatment. METHODOLOGY: In-depth, semi-structured interviews were conducted with 20 hypodontia patients following completion of orthodontic treatment but prior to any planned prosthodontic treatment commencing...
December 2016: Journal of Orthodontics
https://www.readbyqxmd.com/read/27692419/tooth-replacements-in-young-adults-with-severe-hypodontia-orthodontic-space-closure-dental-implants-and-tooth-supported-fixed-dental-prostheses-a-follow-up-study
#20
Christina L Hvaring, Bjørn Øgaard, Kari Birkeland
INTRODUCTION: Children with severe hypodontia have a substantial impairment of their dental health starting early in life. The purpose of this study was to describe types and locations of substitutes for missing teeth in patients with severe hypodontia and to compare the crown and soft tissue morphologies of orthodontic space closure, dental implants, and tooth-supported fixed dental prostheses for replacing teeth in the anterior region. METHODS: Fifty patients missing 6 or more teeth and aged 18 years or older (mean age, 25...
October 2016: American Journal of Orthodontics and Dentofacial Orthopedics
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