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febrile convulsion

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https://www.readbyqxmd.com/read/29422395/diurnal-occurrence-of-complex-febrile-seizure-and-their-severity-in-pediatric-patients-needing-hospitalization
#1
Hiroshi Yamaguchi, Hiroaki Nagase, Yusuke Ishida, Daisaku Toyoshima, Azusa Maruyama, Kazumi Tomioka, Tsukasa Tanaka, Masahiro Nishiyama, Kyoko Fujita, Taniguchi-Ikeda Mariko, Kandai Nozu, Ichiro Morioka, Noriyuki Nishimura, Hiroshi Kurosawa, Satoshi Takada, Yoshiyuki Uetani, Kazumoto Iijima
Several studies describing the diurnal occurrence of febrile seizures have reported greater seizure frequency early or late in the evening relative to midnight or early morning. However, no articles have reported on the diurnal occurrence of complex febrile seizure. Moreover, no studies have addressed the relationship between seizure severity and diurnal occurrence. We retrospectively evaluated complex febrile seizures in 462 children needing hospitalization, and investigated the relationship between severity and diurnal occurrence according to four categorized time periods (morning, afternoon, evening, and night)...
February 5, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29414550/clinical-aspects-neuroimaging-and-electroencephalography-of-35-cases-of-hemiconvulsion-hemiplegia-syndrome
#2
Mohamed Albakaye, Halima Belaïdi, Fatiha Lahjouji, Leila Errguig, Callixte Kuate, Youssoufa Maiga, Seybou Hassane Diallo, Najib Kissani, Reda Ouazzani
INTRODUCTION: The hemiconvulsion-hemiplegia-epilepsy (HHE) syndrome is a rare consequence of febrile seizures during childhood. It is characterized by the presence of prolonged unilateral clonic seizures occurring during febrile illness in a child less than 4years of age. Then, a flaccid unilateral hemiplegia with variable duration occurs. OBJECTIVES: The objective of the study was to describe the clinical, electroencephalogram (EEG), and neuroimaging treatment and outcome of series of cases of HHE syndrome followed for 10years in our clinical neurophysiology department of the specialty hospital of Rabat...
January 26, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29383717/topographic-principles-of-cortical-fluid-attenuated-inversion-recovery-signal-in-temporal-lobe-epilepsy
#3
Sophie Adler, Seok-Jun Hong, Min Liu, Torsten Baldeweg, J Helen Cross, Andrea Bernasconi, Boris C Bernhardt, Neda Bernasconi
OBJECTIVE: In drug-resistant temporal lobe epilepsy (TLE), relative to the large number of whole-brain morphological studies, neocortical T2 changes have not been systematically investigated. The aim of this study was to assess the anatomical principles that govern the distribution of neocortical T2-weighted fluid-attenuated inversion recovery (FLAIR) signal intensity and uncover its topographic principles. METHODS: Using a surface-based sampling scheme, we mapped neocortical FLAIR intensity of 61 TLE patients relative to 38 healthy controls imaged at 3 T...
January 31, 2018: Epilepsia
https://www.readbyqxmd.com/read/29379546/gabrg2-c588t-gene-polymorphisms-might-be-a-predictive-genetic-marker-of-febrile-seizures-and-generalized-recurrent-seizures-a-case-control-study-in-a-romanian-pediatric-population
#4
Anamaria Todoran Butilă, Ancuta Zazgyva, Anca Ileana Sin, Elisabeta Racoș Szabo, Mariana Cornelia Tilinca
Introduction: This case-control study aimed to assess two single nucleotide polymorphisms of the gene encoding the GABRG2 protein - GABRG2 (3145 G>A) and GABRG2 rs 211037 Asn196Asn (C588T) - in a cohort of pediatric patients from Romania, and evaluate their possible impact on drug-resistant forms of generalized epilepsy and recurrent febrile seizures. Material and methods: One hundred and fourteen children with idiopathic generalized epilepsy (group 1) or febrile seizures (group 2) were compared to 153 controls...
January 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29374213/cerebrospinal-fluid-chemokine-patterns-in-children-with-enterovirus-71-related-encephalitis
#5
Jinling Liu, Shuxian Li, Chunyan Cai, Yingchun Xu, Yuan Jiang, Zhimin Chen
Enterovirus 71 (EV71) is a major pathogen that causes hand, foot and mouth disease (HFMD) as well as neurological complications, such as encephalitis. The chemokines involved in the migration of leukocytes have increasingly been implicated in infectious diseases of the central nervous system. Few studies have evaluated the levels of chemokines in HMFD children with EV71-related encephalitis. In the present study, we evaluated the cerebrospinal fluid (CSF) levels of the chemokines IL-8, RANTES, MIG, MCP-1 and IP-10 in 99 children with EV71-related encephalitis and 22 children with febrile convulsion (FC)...
January 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29360435/cerebellar-oxidative-stress-and-fine-motor-impairment-in-adolescent-rats-exposed-to-hyperthermia-induced-seizures-is-prevented-by-maternal-caffeine-intake-during-gestation-and-lactation
#6
María Crespo, David Agustín León-Navarro, Mairena Martín
Febrile seizures (FS) is one of the most common convulsive disorders in infants and young children that only occurs during the first years of life in humans, when the cerebellum is still developing. Several works have shown that maternal caffeine consumption during gestation and lactation can exert protective effects on developing brain under pathological conditions. Here, we have used an animal model of FS to know whether maternal caffeine consumption during gestation and lactation exhibited protective effects on rat cerebellum...
January 19, 2018: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29356811/association-of-time-to-treatment-with-short-term-outcomes-for-pediatric-patients-with-refractory-convulsive-status-epilepticus
#7
Marina Gaínza-Lein, Iván Sánchez Fernández, Michele Jackson, Nicholas S Abend, Ravindra Arya, J Nicholas Brenton, Jessica L Carpenter, Kevin E Chapman, William D Gaillard, Tracy A Glauser, Joshua L Goldstein, Howard P Goodkin, Kush Kapur, Mohamad A Mikati, Katrina Peariso, Robert C Tasker, Dmitry Tchapyjnikov, Alexis A Topjian, Mark S Wainwright, Angus Wilfong, Korwyn Williams, Tobias Loddenkemper
Importance: Treatment delay for seizures can lead to longer seizure duration. Whether treatment delay is associated with major adverse outcomes, such as death, remains unknown. Objective: To evaluate whether untimely first-line benzodiazepine treatment is associated with unfavorable short-term outcomes. Design, Setting, and Participants: This multicenter, observational, prospective cohort study included 218 pediatric patients admitted between June 1, 2011, and July 7, 2016, into the 11 tertiary hospitals in the United States within the Pediatric Status Epilepticus Research Group...
January 22, 2018: JAMA Neurology
https://www.readbyqxmd.com/read/29353090/investigating-the-prevalence-of-febrile-convulsion-in-kayseri-turkey-an-assessment-of-the-risk-factors-for-recurrence-of-febrile-convulsion-and-for-development-of-epilepsy
#8
Mehmet Canpolat, Huseyin Per, Hakan Gumus, Ferhan Elmali, Sefer Kumandas
PURPOSE: The purpose of this study was to investigate the prevalence and recurrence of febrile convulsion (FC) and risk factors for development of epilepsy in school children throughout in the Kayseri provincial center. METHOD: Ten thousand individuals selected using "stratified cluster sampling" from a student population of 259,428 inside the Kayseri Urban Municipality represented the study sample. Fifteen thousand questionnaires were distributed, of which 10,742 (71...
January 10, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29317560/a-new-combined%C3%A2-vaccine%C3%A2-against-measles-mumps-rubella-and-varicella-in-india
#9
Nitin Shah, Raunak Parikh, Giacomo Casabona, Shafi Kolhapure
A quadrivalent MMRV (measles-mumps-rubella-varicella) combination vaccine has recently been launched in India. This vaccine is highly immunogenic, with seroconversion rates against all antigens reaching 96.6-100% at 42 to 56 days after the second vaccine dose in unvaccinated children or in those previously vaccinated with MMR+/-V. Two doses efficacy, against all varicella is 94.1% and effectiveness reaches 91%. The most frequent solicited local adverse event after MMRV vaccine is redness, and fever is the most common solicited general symptom...
December 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/29303140/optic-disc-coloboma-in-two-nigerian-siblings-case-report-and-review-of-literature
#10
Y O Babalola, O O Olawoye, P O Idam
We report two cases of bilateral asymmetric optic disc coloboma (ODC) in siblings. The index patient is a 9-year-old Nigerian girl with severe cognitive deficit who presented with a poor vision of 3 years' duration. She had a history of childhood febrile convulsions and delayed developmental milestones. Her visual acuity could not be assessed because she had a cognitive deficit and expressive aphasia. Ocular examination revealed a very large excavated right optic disc with only a strip of remnant neuro-retinal rim superiorly, and a smaller left optic disc with inferior disc excavation, superior wedge of the pink neuro-retinal rim as well as a temporal optic disc pit...
November 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29285950/prrt2-mutations-in-a-cohort-of-chinese-families-with-paroxysmal-kinesigenic-dyskinesia-and-genotype-phenotype-correlation-reanalysis-in-literatures
#11
Guohua Zhao, Xiaomin Liu, Qiong Zhang, Kang Wang
PURPOSE OF THE STUDY: Though rare, children are susceptible to paroxysmal dyskinesias (PxDs) such as paroxysmal kinesigenic dyskinesia (PKD), and infantile convulsions and choreoathetosis (ICCA, also termed PKD/IC). PKD is characterized by recurrent attacks of involuntary movements mostly starting around puberty, and PKD/IC also presents with clusters of non-febrile seizures at ages between 3 and 12 months in addition to symptoms of PKD. Recent studies showed that the cause of PKD or PKD/IC could be proline-rich transmembrane protein 2 (PRRT2) gene mutations...
December 29, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/29276870/the-long-term-neurodevelopmental-outcomes-of-infants-born-full-term-with-low-birth-weight
#12
Ayşe Tosun, Börte Gürbüz-Özgür, Hatice Aksu, Münevver Kaynak-Türkmen
Tosun A, Gürbüz-Özgür B, Aksu H, Kaynak-Türkmen M. The long-term neurodevelopmental outcomes of infants born full-term with low birth weight. Turk J Pediatr 2017; 59: 169-176. In this study, it was aimed to evaluate the neurological developments of pre-school or school-aged children together with their school successes, intelligence quotient and symptom severity of attention deficit hyperactivity disorder who were born at the 37th gestational week and above with birth weights below tenth percentile, which is called small for gestational age (SGA)...
2017: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/29237494/adherence-to-the-integrated-management-of-childhood-illness-guidelines-in-namibia-kenya-tanzania-and-uganda-evidence-from-the-national-service-provision-assessment-surveys
#13
Carsten Krüger, Monika Heinzel-Gutenbrunner, Mohammed Ali
BACKGROUND: Integrated Management of Childhood Illness (IMCI) is regarded as a standard public health approach to lowering child mortality in developing countries. However, little is known about how health workers adhere to the guidelines at the national level in sub-Saharan African countries. METHODS: Data from the Service Provision Assessment surveys of Namibia (NA) (survey year: 2009), Kenya (KE) (2010), Tanzania (TZ) (2006) and Uganda (UG) (2007) were analysed for adherence to the IMCI guidelines by health workers...
December 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29229893/prognostic-factors-for-epilepsy-following-first-febrile-seizure-in-saudi-children
#14
Abdullah I Almojali, Anwar E Ahmed, Muhammed Y Bagha
BACKGROUND: Febrile seizure is the most common convulsive event during childhood, but it is generally considered benign. OBJECTIVES: To estimate the rate of epilepsy after first presentation of febrile seizure and to describe factors that can predispose children to have subsequent epilepsy after their first febrile seizure. DESIGN: Retrospective chart review. SETTING: A tertiary care center in Riyadh. PATIENTS AND METHODS: All children whose first febrile seizure developed between 2009-2012, and who were admitted to the pediatric wards...
November 2017: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/29120117/is-apolipoprotein-e-%C3%AE%C2%B52-associated-with-delayed-onset-of-non-lesional-temporal-lobe-epilepsy
#15
Davor Sporiš, Silvio Bašić, Jadranka Sertić, Darija Mahović Lakušić, Tomislav Babić
The aim of the study was to evaluate the possible association between Apo E polymorphisms and age at seizure onset in patients with non-lesional temporal lobe epilepsy. Eighty patients with non-lesional temporal lobe epilepsy with or without bilateral tonic-clonic propagation were analyzed. Age at seizure onset was defined as age at the first unequivocal seizure (excluding febrile convulsions). ApoE alleles were determined by a procedure where genome DNA was amplified by chain reaction along with polymerase, using the LightCycler kit (Roche) for ApoE mutations on codons 112 and 158...
March 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29067083/the-long-term-prognosis-of-epilepsy-patients-with-medically-treated-over-a-period-of-eight-years-in-turkey
#16
Pelin Duman, Asuman Orhan Varoglu, Esra Kurum
OBJECTIVE: The aim of this study was to investigate the effect of demographic and clinical characteristics on temporal changes in seizure control and frequency in medically treated epilepsy patients to guide treatment modalities. METHODS: We retrospectively analyzed the association between clinical and demographic characteristics and seizure frequency in 1329 epilepsy patients who were followed up at an outpatient clinic for one to eight years, 2008-2015.. RESULTS: Younger age at first seizure (p = 0...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28959664/neuropharmacological-profile-and-chemical-analysis-of-fresh-rhizome-essential-oil-of-curcuma-longa-turmeric-cultivated-in-southwest-nigeria
#17
Idris A Oyemitan, Christianah A Elusiyan, Ayoola O Onifade, Moses A Akanmu, Adebola O Oyedeji, Armando G McDonald
BACKGROUND: Curcuma longa (turmeric) is commonly used as spice and also used to treat fever, cough and febrile convulsions in Nigeria. This study determined the chemical composition of the essential oil of C. longa and evaluated its neuropharmacological activity in mice. METHODS: Essential oil of C. longa (EOCL) fresh rhizome was obtained by hydrodistillation and its chemical composition determined by GC-MS. Acute toxicity (LD50) profile of the essential oil was determined orally (p...
2017: Toxicology Reports
https://www.readbyqxmd.com/read/28957722/relationship-between-iron-deficiency-anemia-and-febrile-seizures-in-children-a-systematic-review-and-meta-analysis
#18
Byung Ok Kwak, Kyungmin Kim, Soo-Nyung Kim, Ran Lee
PURPOSE: The association between iron deficiency anemia (IDA) and febrile seizures (FS) during childhood is inconclusive due to inconsistent results reported in different studies. We performed a systematic review and meta-analysis to determine an association between IDA and FS in children. METHODS: We searched PubMed, EMBASE, and Cochrane Library databases for studies published up to August 2015 using the following key words: ["iron deficiency" OR "iron status"] AND ["febrile seizure" OR "febrile convulsion"] AND ["pediatric" OR "infant" OR "child"]...
November 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28941835/pharmacoresistance-with-newer-anti-epileptic-drugs-in-mesial-temporal-lobe-epilepsy-with-hippocampal-sclerosis
#19
Michael S Pohlen, Jingxiao Jin, Ronnie S Tobias, Atul Maheshwari
This study aims to evaluate the overall prognosis, prognostic factors, and efficacy of treatment in patients with mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) who have access to third generation anti-epileptic drugs but not to epilepsy surgery. Eighty-five MTLE-HS patients were retrospectively placed into a seizure-free (seizure-free for >1year) or drug-resistant group, and the two groups were compared on the basis of age, sex, age at onset of seizures, duration of epilepsy, side of lesion, handedness, EEG findings, history of CNS infection, history of febrile convulsions, history of head trauma, history of cognitive impairment, family history of seizures, number of current anti-epileptic drugs (AEDs), total number of AED trials, and presence of individual AEDs...
November 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28886185/clinical-features-and-seasonality-of-parechovirus-infection-in-an-asian-subtropical-city-hong-kong
#20
Grace P K Chiang, Zigui Chen, Martin C W Chan, Simon H M Lee, Angela K Kwok, Apple C M Yeung, E Anthony S Nelson, Kam Lun Hon, Ting Fan Leung, Paul K S Chan
BACKGROUND: The epidemiology of human parechovirus (HPeV) in Asia remains obscure. We elucidated the prevalence, seasonality, type distribution and clinical presentation of HPeV among children in Hong Kong. METHODS: A 24-month prospective study to detect HPeV in children ≤36 months hospitalized for acute viral illnesses. RESULTS: 2.3% of the 3911 children examined had HPeV infection, with most (87.5%) concentrated in September-January (autumn-winter)...
2017: PloS One
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