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https://www.readbyqxmd.com/read/28654555/the-experience-of-pain-dismissal-in-adolescence
#1
Ellen K Defenderfer, Kate Bauer, Eva Igler, Julia A Uihlein, W Hobart Davies
CONTEXT: Pain in adolescence has psychosocial effects lasting into adulthood, including increased likelihood of pain in adulthood and higher rates of depression and anxiety. Many adolescents with chronic pain describe skepticism of pain reports, but this has not yet been evaluated in a sample of typically developing adolescents. OBJECTIVE: The current study sought to describe the experience of perceived pain dismissal during adolescence in a community sample. METHOD: Nearly two-thousand (1931) emerging adults were recruited from the community and answered open-ended questions regarding whether they had experienced dismissal of their pain in adolescence, who dismissed their pain, characteristics of the dismisser, and what that experience was like...
June 16, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28643185/keeping-disability-in-mind-a-case-study-in-implantable-brain-computer-interface-research
#2
Laura Specker Sullivan, Eran Klein, Tim Brown, Matthew Sample, Michelle Pham, Paul Tubig, Raney Folland, Anjali Truitt, Sara Goering
Brain-Computer Interface (BCI) research is an interdisciplinary area of study within Neural Engineering. Recent interest in end-user perspectives has led to an intersection with user-centered design (UCD). The goal of user-centered design is to reduce the translational gap between researchers and potential end users. However, while qualitative studies have been conducted with end users of BCI technology, little is known about individual BCI researchers' experience with and attitudes towards UCD. Given the scientific, financial, and ethical imperatives of UCD, we sought to gain a better understanding of practical and principled considerations for researchers who engage with end users...
June 22, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28639822/exposure-to-alcohol-advertising-and-adolescents-drinking-beliefs-role-of-message-interpretation
#3
Rebecca L Collins, Steven C Martino, Stephanie A Kovalchik, Elizabeth J D'Amico, William G Shadel, Kirsten M Becker, Anagha Tolpadi
OBJECTIVE: Recent research revealed momentary associations between exposure to alcohol advertising and positive beliefs about alcohol among adolescents (Martino et al., 2016). We reanalyzed those data to determine whether associations depend on adolescents' appraisal of ads. METHOD: Over a 10-month period in 2013, 589 youth, ages 11-14, in the Los Angeles, CA, area, participated in a 14-day ecological momentary assessment, logging all exposures to alcohol advertisements as they occurred and completing brief assessments of their skepticism toward, liking of, and identification with any people in each ad, as well as their alcohol-related beliefs at the moment...
June 22, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28639739/philosophical-aesthetics-and-cognitive-science
#4
REVIEW
Aaron Meskin, Jon Robson, Anna Ichino, Kris Goffin, Annelies Monseré
Philosophical aesthetics is the branch of philosophy which explores issues having to do with art, beauty, and related phenomena. Philosophers have often been skeptical about the place of empirical investigation in aesthetics. However, in recent years many philosophical aestheticians have turned to cognitive science to enrich their understanding of their subject matter. Cognitive scientists have, in turn, been inspired by work in philosophical aesthetics. This essay focuses on a representative subset of the areas in which there has been fruitful dialog between philosophical aestheticians and cognitive scientists...
June 22, 2017: Wiley Interdisciplinary Reviews. Cognitive Science
https://www.readbyqxmd.com/read/28633290/planning-evaluating-and-vetting-receptor-signaling-studies-to-assesshyaluronan-size-dependence-and-specificity
#5
Paul H Weigel
Exciting discoveries in many diverse fields of hyaluronan (HA) biology over the last 40 years have centered around the ability of HA to bind cell surface HA receptors (e.g. CD44, Layilin, LYVE-1, HARE/Stab2 and RHAMM) and sometimes also to activate intracellular signal transduction pathways, frequently involving ERK1/2. Though perplexing, a major characteristic of HA-mediated signal pathway activation for some receptors has been a dependence on the size of the bound HA. Receptors that directly interact with HA, which may not include TLR2/4, bind very well to any HA molecule > 8-20 sugars, depending on the receptor...
June 13, 2017: Glycobiology
https://www.readbyqxmd.com/read/28627179/water-lean-solvents-for-post-combustion-co2-capture-fundamentals-uncertainties-opportunities-and-outlook
#6
David J Heldebrant, Phillip K Koech, Vassiliki-Alexandra Glezakou, Roger Rousseau, Deepika Malhotra, David C Cantu
This review is designed to foster the discussion regarding the viability of postcombustion CO2 capture by water-lean solvents, by separating fact from fiction for both skeptics and advocates. We highlight the unique physical and thermodynamic properties of notable water-lean solvents, with a discussion of how such properties could translate to efficiency gains compared to aqueous amines. The scope of this review ranges from the purely fundamental molecular-level processes that govern solvent behavior to bench-scale testing, through process engineering and projections of process performance and cost...
June 19, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/28625744/the-anterior-sagittal-transrectal-approach-astra-for-cases-associated-with-rectal-implantation-of-the-urethra-a-retrospective-review-of-six-cases
#7
A Macedo, M I S Silva, J A Pompermaier, S L Ottoni, R de Castro, M Leal da Cruz
INTRODUCTION: Severe genital abnormalities such as urogenital sinus and urethral duplication with ectopic urethra in the rectum represent a major challenge in reconstructive urology. OBJECTIVE: We aimed to review our cases presenting with functional ectopic urethra implanted in the rectum that were treated through an ASTRA approach. METHODS: We reviewed the medical records of all patients who had undergone an ASTRA approach from 2005-2016...
May 17, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28623378/carotid-stenting-in-neuroradiology-a%C3%A2-short-journey-from-the-past-to-current-debates
#8
REVIEW
Joachim Berkefeld, Marlies Wagner, Richard du Mesnil
After a period of stagnation due to negative results of randomized trials for patients with symptomatic stenosis, the relevance of carotid artery stenting (CAS) is increasing again. CAS has become an important and evidence-based part of interventional stroke treatment. Our ability to manage acute recanalization of carotid occlusions and other niche indications properly led some skeptical neurologists to trust in carotid intervention for elective cases as well. The evolution of CAS from initial euphoria to more realistic views under consideration of trial results and guidelines is reviewed...
June 16, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/28622829/investigation-of-j-shaped-dose-responses-induced-by-exposure-to-the-alkylating-agent-n-methyl-n-nitrosourea
#9
Katherine E Chapman, George R Hoffmann, Shareen H Doak, Gareth J S Jenkins
Hormesis is defined as a biphasic dose-response where biological effects of low doses of a stressor demonstrate the opposite effect to high-dose effects of the same stressor. Hormetic, or J-shaped, dose-response relationships are relatively rarely observed in toxicology, resulting in a limited understanding and even some skepticism of the concept. Low dose-response studies for genotoxicity endpoints have been performed at Swansea University for over a decade. However, no statistically significant decreases below control genotoxicity levels have been detected until recently...
July 2017: Mutation Research
https://www.readbyqxmd.com/read/28619407/should-they-also-have-babies-community-attitudes-toward-sexual-and-reproductive-rights-of-people-living-with-hiv-aids-in-nigeria
#10
Zubairu Iliyasu, Hadiza S Galadanci, Yusuf A Ibrahim, Musa Babashani, Mohammed S Mijinyawa, Melynda Simmons, Muktar H Aliyu
BACKGROUND: People living with HIV have the right to healthy, satisfying sex lives and to appropriate services to ensure their sexual and reproductive health, including having healthy children. The reproductive rights of people living with HIV/AIDS are, however, often met with skepticism and discrimination, despite recent advances in HIV treatment. OBJECTIVE: To assess the attitudes of community members in Kano, Nigeria, toward the right of persons living with HIV/AIDS to have healthy sexual relationships and bear children...
March 2017: Annals of Global Health
https://www.readbyqxmd.com/read/28611985/adaptation-through-collaboration-developing-novel-platforms-to-advance-the-delivery-of-advanced-therapies-to-patients
#11
REVIEW
Magdalini Papadaki
For the nascent field of advanced therapies, collaboration will be a game-changer, turning scientific progress that was once unimaginable into transformative medical practice. Despite promise for lifelong management and even cure of disease, skepticism remains about the feasibility of their delivery to patients, fueling investment risks. With the potential for long-term effectiveness in need of frequent reassessment, current approaches to predict real-life drug performance bear little relevance, necessitating novel and iterative schemes to monitoring the benefit-risk profiles throughout the life span of advanced therapies...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28600661/controversy-of-single-versus-staged-management-of-anorectal-malformations
#12
Ajay Narayan Gangopadhyay, Vaibhav Pandey
Anorectal malformations' (ARMs) management has taken strides over the past few decades. The advent of Posterior sagittal anorectoplasty (PSARP) and its acceptance by most people across the globe as standard procedure has given way to a debate of single vs. three-staged repair. After initial hesitancy and lot of skepticism, single-staged repair has very well established its role because of its advantages over the staged procedure. There is enough evidence which suggests that single-staged repair has got equally good outcome as that of staged repair (if not better)...
June 10, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28594673/facilitators-and-barriers-for-interprofessional-rounding-a-qualitative-study
#13
Susan Hendricks, Virginia Julie LaMothe, Areeba Kara, Joan Miller
PURPOSE: The purpose of this qualitative study was to describe the barriers and facilitators for interprofessional patient-centered rounding across 4 acute care units in a large urban hospital. DESIGN: A qualitative descriptive method that included data gathered over an 18-month period was used. METHODS: Three data sources were included: participant observation of rounding activities, focused meetings related to interprofessional practice, and exit interviews with key informants representing multiple professions and roles...
July 2017: Clinical Nurse Specialist CNS
https://www.readbyqxmd.com/read/28590885/optimistic-bias-advertising-skepticism-and-consumer-intentions-for-seeking-information-about-the-health-risks-of-prescription-medicine
#14
Jin Seong Park, Ho-Young Anthony Ahn, Eric John Haley
Based on a survey of prescription drug users (N = 408), this study revealed that: (a) the frequency of consumers' personal experience of prescription medicine adverse reactions negatively related to the extent of their optimistic bias about the chances of such events, (b) consumers' perceived personal control over adverse reactions positively related to optimistic bias, and (c) optimistic bias related more negatively to intentions to seek risk information when consumer skepticism toward direct-to-consumer advertising was high...
April 2017: Health Marketing Quarterly
https://www.readbyqxmd.com/read/28589328/results-from-the-field-development-and-evaluation-of-a-psychiatry-residency-training-rotation-in-cognitive-behavioral-therapies
#15
Barbara W Kamholz, Amy E Lawrence, Gabrielle I Liverant, Shimrit K Black, Justin M Hill
OBJECTIVE: The goal of this project was to develop and evaluate a new residency training rotation focused on cognitive-behavioral therapies (CBT) and to assess outcomes across multiple domains. METHODS: Data are presented from 30 psychiatry residents. Primary learning-related outcomes included content knowledge, self-efficacy, and attitudes and behavioral intentions towards evidence-based psychotherapies (e.g., CBT). RESULTS: Residents reported significant increases in CBT knowledge, CBT-specific self-efficacy, overall psychotherapy self-efficacy, belief in patient benefit from CBT, and behavioral intention to use CBT...
June 6, 2017: Academic Psychiatry
https://www.readbyqxmd.com/read/28573422/how-to-evaluate-the-potential-occurrence-of-intraguild-predation
#16
Morgana Maria Fonseca, Marta Montserrat, Celeste Guzmán, Inmaculada Torres-Campos, Angelo Pallini, Arne Janssen
Intraguild predation is the combination of exploitative competition and predation among potential competitors that use similar resources. It has the potential to shape population dynamics and community structure. Although there is much empirical evidence for the occurrence of intraguild predation in natural ecosystems, the study of its effects is mainly limited to short-term microcosm experiments. There is, therefore, certain skepticism about its actual significance in nature. A relevant concern is that there is no consensus regarding criteria to evaluate the possible occurrence of intraguild predation in short-term experiments, and methodological differences may therefore underlie apparent inconsistencies among studies...
June 1, 2017: Experimental & Applied Acarology
https://www.readbyqxmd.com/read/28559332/rifamycin-action-on-rna-polymerase-in-antibiotic-tolerant-mycobacterium-tuberculosis-results-in-differentially-detectable-populations
#17
Kohta Saito, Thulasi Warrier, Selin Somersan-Karakaya, Lina Kaminski, Jianjie Mi, Xiuju Jiang, Suna Park, Kristi Shigyo, Ben Gold, Julia Roberts, Elaina Weber, William R Jacobs, Carl F Nathan
Mycobacterium tuberculosis (Mtb) encounters stresses during the pathogenesis and treatment of tuberculosis (TB) that can suppress replication of the bacteria and render them phenotypically tolerant to most available drugs. Where studied, the majority of Mtb in the sputum of most untreated subjects with active TB have been found to be nonreplicating by the criterion that they do not grow as colony-forming units (cfus) when plated on agar. However, these cells are viable because they grow when diluted in liquid media...
June 13, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28558337/relationship-between-substance-use-and-attitudes-towards-seeking-professional-psychological-help-among-veterans-filing-ptsd-claims
#18
Sarah Meshberg-Cohen, Lorig Kachadourian, Anne C Black, Marc I Rosen
INTRODUCTION: Veterans in distress often do not seek mental health treatment, even when such services are available. Substance use may further undermine treatment-seeking, given its association with negative treatment views. This study examined attitudes towards seeking psychological help in a sample of veterans diagnosed with posttraumatic stress disorder (PTSD), with and without co-occurring substance use disorders (SUD). METHODS: Altogether, 143 male OEF/OIF veterans filing service-connected benefits claims for PTSD completed the Attitudes Towards Seeking Professional Psychological Help-Short Form (ATSPPH-SF) and other baseline assessments...
May 23, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28555108/is-the-comparison-between-exercise-and-pharmacologic-treatment-of-depression-in-the-clinical-practice-guideline-of-the-american-college-of-physicians-evidence-based
#19
Yael Netz
Major depression disorder is most commonly treated with antidepressants. However, due to their side effects clinicians seek non-pharmacologic options, and one of these is exercise. The literature on the benefits of exercise for depression is extensive. Nevertheless, two recent reviews focusing on antidepressants vs. other therapies as a basis for clinical practice guidelines recommended mainly antidepressants, excluding exercise as a viable choice for treatment of depression. The aim of this perspective is to analyze the literature exploring the reasons for this discrepancy...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28554500/semantic-network-analysis-of-vaccine-sentiment-in-online-social-media
#20
Gloria J Kang, Sinclair R Ewing-Nelson, Lauren Mackey, James T Schlitt, Achla Marathe, Kaja M Abbas, Samarth Swarup
OBJECTIVE: To examine current vaccine sentiment on social media by constructing and analyzing semantic networks of vaccine information from highly shared websites of Twitter users in the United States; and to assist public health communication of vaccines. BACKGROUND: Vaccine hesitancy continues to contribute to suboptimal vaccination coverage in the United States, posing significant risk of disease outbreaks, yet remains poorly understood. METHODS: We constructed semantic networks of vaccine information from internet articles shared by Twitter users in the United States...
June 22, 2017: Vaccine
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