keyword
MENU ▼
Read by QxMD icon Read
search

Skeptic

keyword
https://www.readbyqxmd.com/read/28826513/slicing-the-cortex-to-study-mental-illness-alois-alzheimer-s-pictures-of-equivalence
#1
Lara Keuck
Alois Alzheimer (1864-1915) was a German physician who specialized in psychiatry, and who is today known for the first description of a-in his own words-peculiar ailment (eigenartige Erkrankung), which was named after him. In his time, however, he was foremost recognized for his work in refining histopathological techniques and thereby contributing to the methodological arsenal for differential diagnosis in clinical psychiatry. In his laboratory that was based at the renowned Munich Psychiatric University Clinic led by Emil Kraepelin (1856-1926), Alzheimer, his assistants, and students conserved, prepared, and studied slices of deceased patients' brains under the microscope...
2017: Progress in Brain Research
https://www.readbyqxmd.com/read/28821684/medication-overuse-headache-an-entrenched-idea-in-need-of-scrutiny
#2
REVIEW
Ann I Scher, Paul B Rizzoli, Elizabeth W Loder
It is a widely accepted idea that medications taken to relieve acute headache pain can paradoxically worsen headache if used too often. This type of secondary headache is referred to as medication overuse headache (MOH); previously used terms include rebound headache and drug-induced headache. In the absence of consensus about the duration of use, amount, and type of medication needed to cause MOH, the default position is conservative. A common recommendation is to limit treatment to no more than 10 or 15 days per month (depending on medication type) to prevent headache frequency progression...
August 18, 2017: Neurology
https://www.readbyqxmd.com/read/28811152/how-does-media-coverage-effect-the-consumption-of-antidepressants-a-study-of-the-media-coverage-of-antidepressants-in-danish-online-newspapers-2010-2011
#3
Michael Green Lauridsen, Sofia Kälvemark Sporrong
BACKGROUND: The news media has become a major source of health information for the public, and hence vital in the individuals' opinions and decisions about health topics. The first decrease in the usage of antidepressants in Denmark in over a decade happened alongside an intensive period of media coverage about antidepressants. OBJECTIVES: The aim of this study was to examine the Danish media's coverage of antidepressants during 2010-2011 in order to explore what influence it could have had on the change in the use of antidepressants...
August 2, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28810975/adaptation-of-screening-brief-intervention-referral-to-treatment-to-active-duty-military-personnel-in-an-emergency-department-findings-from-a-formative-research-study
#4
Megan Holt, Mark Reed, Susan I Woodruff, Gerard DeMers, Michael Matteucci, Suzanne L Hurtado
BACKGROUND: The transient nature of military life coupled with environmental and psychosocial stressors increase the risk for alcohol misuse and abuse among active duty (AD) military service members and recent epidemiological studies demonstrate high rates of heavy drinking among AD personnel. Over the past decade, Department of Defense health care systems have observed increases in the utilization of substance use services among military personnel demobilizing from Operation Enduring Freedom and Operation Iraqi Freedom...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28802467/complementary-therapies-for-mental-health-disorders
#5
REVIEW
Gary N Asher, Jonathan Gerkin, Bradley N Gaynes
Approximately 18% of the US adult population has a mental illness, yet only 13% with mental illness receive any treatment. Although pharmacotherapy and psychotherapy are the mainstays of treatment, treatment discontinuation and failure are common. Skepticism toward such treatments has fueled interest in and use of complementary therapies, such as acupuncture, meditation, and natural products. Many medical providers are unaware of the use of these therapies by their patients, and knowledge of the evidence base for these therapies is often lacking...
September 2017: Medical Clinics of North America
https://www.readbyqxmd.com/read/28800722/randomized-comparison-of-sevoflurane-versus-propofol-remifentanil-on-the-cardioprotective-effects-in-elderly-patients-with-coronary-heart-disease
#6
Yunlong Zhang, Wendong Lin, Sheliang Shen, Hongfa Wang, Xiaona Feng, Jiehao Sun
BACKGROUND: It is skeptical about cardioprotective property of sevoflurane in patients undergoing noncardiac surgery, especially in the elderly patients with coronary heart disease. We hypothesized that long duration of sevoflurane inhalation in noncardiac surgery could ameliorate myocardial damage in such patients. METHODS: This was a randomized, prospective study. One hundred twenty-one elderly patients with coronary heart disease were randomly allocated into two groups...
August 11, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28782190/epigenetic-germline-inheritance-in-mammals-looking-to-the-past-to-understand-the-future
#7
REVIEW
Katharina Gapp, Johannes Bohacek
Life experiences can induce epigenetic changes in mammalian germ cells, which can influence the developmental trajectory of the offspring and impact health and disease across generations. While this concept of epigenetic germline inheritance has long been met with skepticism, evidence in support of this route of information transfer is now overwhelming, and some key mechanisms underlying germline transmission of acquired information are emerging. This review focusses specifically on sperm RNAs as causal vectors of inheritance...
August 7, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/28774910/the-stem-cell-skeptic
#8
Kelly Servick
No abstract text is available yet for this article.
August 4, 2017: Science
https://www.readbyqxmd.com/read/28765464/the-effect-of-new-oral-care-technologies-on-the-need-for-dentists-in-2040
#9
Peter M Milgrom, Jeremy A Horst
This article addresses changes in technology of oral self-care or professional care that may increase or decrease the demand for dentists by 2040. The focus is on dental caries, periodontitis, and temporomandibular joint disorders (TMD), as the first two are the main areas of current practice and because TMD is an area for growth. To address this question, the authors examined the scientific literature and government registries to identify recent or soon-to-be-available technologies. They also examined the state of translational efficiency, dissemination, and adoption of advances into dental practice...
August 2017: Journal of Dental Education
https://www.readbyqxmd.com/read/28761366/colorectal-endoscopic-submucosal-dissection-patient-selection-and-special-considerations
#10
REVIEW
Andrew Emmanuel, Shraddha Gulati, Margaret Burt, Bu'Hussain Hayee, Amyn Haji
Endoscopic submucosal dissection (ESD) enables en bloc resection of large complex colorectal superficial neoplastic lesions, resulting in very low rates of local recurrence, high-quality pathologic specimens for accurate histopathologic diagnosis and potentially curative treatment of early adenocarcinoma without resorting to major surgical resection. The safety and efficacy of the technique, which was pioneered in the upper gastrointestinal tract, has been established by the consistently impressive outcomes from expert centers in Japan and some other eastern countries...
2017: Clinical and Experimental Gastroenterology
https://www.readbyqxmd.com/read/28759803/no-evidential-value-in-samples-of-transcranial-direct-current-stimulation-tdcs-studies-of-cognition-and-working-memory-in-healthy-populations
#11
Jared Medina, Samuel Cason
A substantial number of studies have been published over the last decade, claiming that transcranial direct current stimulation (tDCS) can influence performance on cognitive tasks. However, there is some skepticism regarding the efficacy of tDCS, and evidence from meta-analyses are mixed. One major weakness of these meta-analyses is that they only examine outcomes in published studies. Given biases towards publishing positive results in the scientific literature, there may be a substantial "file-drawer" of unpublished negative results in the tDCS literature...
July 13, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28750030/minimally-inconsistent-reasoning-in-semantic-web
#12
Xiaowang Zhang
Reasoning with inconsistencies is an important issue for Semantic Web as imperfect information is unavoidable in real applications. For this, different paraconsistent approaches, due to their capacity to draw as nontrivial conclusions by tolerating inconsistencies, have been proposed to reason with inconsistent description logic knowledge bases. However, existing paraconsistent approaches are often criticized for being too skeptical. To this end, this paper presents a non-monotonic paraconsistent version of description logic reasoning, called minimally inconsistent reasoning, where inconsistencies tolerated in the reasoning are minimized so that more reasonable conclusions can be inferred...
2017: PloS One
https://www.readbyqxmd.com/read/28746757/de-extinction-and-barriers-to-the-application-of-new-conservation-tools
#13
Philip J Seddon
Decades of globally coordinated work in conservation have failed to slow the loss of biodiversity. To do better-even if that means nothing more than failing less spectacularly-bolder thinking is necessary. One of the first possible conservation applications of synthetic biology to be debated is the use of genetic tools to resurrect once-extinct species. Since the currency of conservation is biodiversity and the discipline of conservation biology was formed around the prevention of species extinctions, the prospect of reversing extinctions might have been expected to generate unreserved enthusiasm...
July 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28733271/telerehabilitation-review-of-the-state-of-the-art-and-areas-of-application
#14
REVIEW
Alessandro Peretti, Francesco Amenta, Seyed Khosrow Tayebati, Giulio Nittari, Syed Sarosh Mahdi
BACKGROUND: Telemedicine applications have been increasing due to the development of new computer science technologies and of more advanced telemedical devices. Various types of telerehabilitation treatments and their relative intensities and duration have been reported. OBJECTIVE: The objective of this review is to provide a detailed overview of the rehabilitation techniques for remote sites (telerehabilitation) and their fields of application, with analysis of the benefits and the drawbacks related to use...
July 21, 2017: JMIR Rehabil Assist Technol
https://www.readbyqxmd.com/read/28731824/evolutionary-scenarios-and-primate-natural-history
#15
Harry W Greene
Scenarios summarize evolutionary patterns and processes by interpreting organismal traits and their natural history correlates in a phylogenetic context. They are constructed by (1) describing phenotypes (including physiology and behavior), ideally with attention to formative roles of development, experience, and culture; (2) inferring homologies, homoplasies, ancestral character states, and their transformations with phylogenetic analyses; and (3) integrating those components with ecological and other ancillary data...
August 2017: American Naturalist
https://www.readbyqxmd.com/read/28727818/prep-in-italy-the-time-may-be-ripe-but-who-s-paying-the-bill-a-nationwide-survey-on-physicians-attitudes-towards-using-antiretrovirals-to-prevent-hiv-infection
#16
Antonio Di Biagio, Niccolò Riccardi, Alessio Signori, Renato Maserati, Silvia Nozza, Andrea Gori, Stefano Bonora, Marco Borderi, Diego Ripamonti, Maria Cristina Rossi, Giancarlo Orofino, Tiziana Quirino, Giuseppe Nunnari, Benedetto Maurizio Celesia, Salvatore Martini, Caterina Sagnelli, Giovanni Mazzola, Pietro Colletti, Dario Bartolozzi, Teresa Bini, Nicoletta Ladisa, Filippo Castelnuovo, Annalisa Saracino, Sergio Lo Caputo
Several studies have demonstrated the efficacy of the oral pre-exposure prophylaxis (PrEP) with tenofovir (with or without emtricitabine) on preventing HIV-negative partners of HIV infected patients to become infected through sexual contacts. PrEP is already available in the United States and now is approved by European Medicine Agency. In this setting we would like to gauge physicians' knowledge, acquaintance with and attitude to include PrEP in their clinical practice. A cross sectional survey was conducted among Italian physicians expert on antiretroviral therapy...
2017: PloS One
https://www.readbyqxmd.com/read/28726454/attitude-roots-and-jiu-jitsu-persuasion-understanding-and-overcoming-the-motivated-rejection-of-science
#17
Matthew J Hornsey, Kelly S Fielding
There is a worryingly large chasm between scientific consensus and popular opinion. Roughly one third of Americans are skeptical that humans are primarily responsible for climate change; rates of some infectious diseases are climbing in the face of anti-immunization beliefs; and significant numbers of the population worldwide are antievolution creationists. It is easy to assume that resistance to an evidence-based message is a result of ignorance or failure to grasp evidence (the "deficit model" of science communication)...
July 2017: American Psychologist
https://www.readbyqxmd.com/read/28726292/-in-visibility-online-the-benefits-of-online-patient-forums-for-people-with-a-hidden-illness-the-case-of-multiple-chemical-sensitivities-mcs
#18
Tarryn Phillips, Tyson Rees
Sufferers of medically unexplained conditions that are not observable in the clinic can experience multiple layers of invisibility: a lack of biomedical diagnosis; legal skepticism; political disinterest; and a loss of their prior social identity. For those with environmental sensitivities, this is compounded by literal hiddenness due to often being housebound. Drawing on an online survey of people with multiple chemical sensitivity, this article examines how the everyday experience of invisibility is mitigated by engaging with other patients online...
July 20, 2017: Medical Anthropology Quarterly
https://www.readbyqxmd.com/read/28723841/military-civilian-partnership-in-device-innovation-development-commercialization-and-application-of-resuscitative-endovascular-balloon-occlusion-of-the-aorta-reboa
#19
Todd E Rasmussen, Jonathan L Eliason
Noncompressible torso hemorrhage (NCTH) and shock is a leading cause of trauma-related mortality and evidence suggests that survival from this injury pattern has not improved in decades. As such, innovating new approaches and devices, including technologies which can be used by providers within a short of time after severe injury, is a priority for the military. Guided by wartime observations, and through partnerships with civilian academia and private investment, the military has led an effort to define resuscitative endovascular balloon occlusion of the aorta (REBOA) and assess its potential to address this problem...
July 19, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28718803/serum-albumin-binding-and-esterase-activity-mechanistic-interactions-with-organophosphates
#20
Nikolay V Goncharov, Daria A Belinskaia, Vladimir I Shmurak, Maxim A Terpilowski, Richard O Jenkins, Pavel V Avdonin
The albumin molecule, in contrast to many other plasma proteins, is not covered with a carbohydrate moiety and can bind and transport various molecules of endogenous and exogenous origin. The enzymatic activity of albumin, the existence of which many scientists perceive skeptically, is much less studied. In toxicology, understanding the mechanistic interactions of organophosphates with albumin is a special problem, and its solution could help in the development of new types of antidotes. In the present work, the history of the issue is briefly examined, then our in silico data on the interaction of human serum albumin with soman, as well as comparative in silico data of human and bovine serum albumin activities in relation to paraoxon, are presented...
July 18, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
keyword
keyword
102213
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"