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https://www.readbyqxmd.com/read/28324806/social-networking-site-sns-use-by-adolescent-mothers-can-social-support-and-social-capital-be-enhanced-by-online-social-networks-a-structured-review-of-the-literature
#1
REVIEW
Samantha Nolan, Joyce Hendricks, Sally Ferguson, Amanda Towell
AIMS AND OBJECTIVES: to critically appraise the available literature and summarise the evidence relating to adolescent mothers' use of social networking sites in terms of any social support and social capital they may provide and to identify areas for future exploration. BACKGROUND: social networking sites have been demonstrated to provide social support to marginalised individuals and provide psycho-social benefits to members of such groups. Adolescent mothers are at risk of; social marginalisation; anxiety disorders and depressive symptoms; and poorer health and educational outcomes for their children...
March 7, 2017: Midwifery
https://www.readbyqxmd.com/read/28324595/recent-advances-in-developing-antiviral-therapies-for-respiratory-syncytial-virus
#2
REVIEW
Brian C Shook, Kai Lin
Respiratory syncytial virus (RSV) infection presents a significant health challenge in small children, the elderly and immunocompromised patients. There is still a high unmet medical need among patients with RSV infection, and no specific antiviral therapy is available. The only approved agents are palivizumab, which has to be given prophylactically, mainly in high-risk infants, and ribavirin, which is rarely used due to toxicity concerns and questionable benefits. Efforts to develop new antiviral agents have been hampered by the perceived need for high safety hurdles in pediatric patient populations use and the lack of well-characterized druggable targets...
April 2017: Topics in Current Chemistry (Journal)
https://www.readbyqxmd.com/read/28323967/all-cause-mortality-in-patients-with-diabetes-under-treatment-with-dapagliflozin-a-population-based-open-cohort-study-in-thin-database
#3
Konstantinos A Toulis, Brian H Willis, Tom Marshall, Balachadran Kumarendran, Krishna Gokhale, Sandip Ghosh, G Neil Thomas, Kar Keung Cheng, Parth Narendran, Wasim Hanif, Krishnarajah Nirantharakumar
Context: Empagliflozin was found to decrease mortality in patients with type 2 diabetes (T2DM) and a prior cardiovascular (CVD) event. Objectives: To establish whether these benefits can be replicated in a real-world setting, should be expected with the use of dapagliflozin, and apply to T2DM patients at low risk of CVD. Design: General Practice, population-based, retrospective cohort study (January 2013-September 2015). Setting: The Health Improvement Network Database (THIN)...
February 20, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28323829/potentially-modifiable-lifestyle-factors-cognitive-reserve-and-cognitive-function-in-later-life-a-cross-sectional-study
#4
Linda Clare, Yu-Tzu Wu, Julia C Teale, Catherine MacLeod, Fiona Matthews, Carol Brayne, Bob Woods
BACKGROUND: Potentially modifiable lifestyle factors may influence cognitive health in later life and offer potential to reduce the risk of cognitive decline and dementia. The concept of cognitive reserve has been proposed as a mechanism to explain individual differences in rates of cognitive decline, but its potential role as a mediating pathway has seldom been explored using data from large epidemiological studies. We explored the mediating effect of cognitive reserve on the cross-sectional association between lifestyle factors and cognitive function in later life using data from a population-based cohort of healthy older people...
March 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28323768/use-of-cardiovascular-age-for-assessing-risks-and-benefits-of-menopausal-hormone-therapy
#5
Richard J Santen
The Women's Health Initiative studies and others have suggested that menopausal hormone therapy may enhance the risk of new cardiovascular (CV) events in older women and diminish the development of coronary atherosclerosis in younger women. The underlying mechanisms to explain these findings are encapsulated in the term "Timing Hypothesis." Extensive pathophysiologic studies have provided mechanistic evidence for the dichotomous effects of estrogen on coronary artery vasculature. Early in the atherosclerotic disease process, estrogen exerts protective effects on the endothelium and retards plaque formation...
March 20, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28323690/organizational-structural-design-in-spine-care
#6
Alok D Sharan, Gregory D Schroeder, Michael E West, Alexander R Vaccaro
For a company to provide high value to its customers, its organization design is critical. As health care transitions to a value-based model, it is critical that spinal care organizations are structured in such a way that they can maximize value to both the patient and the payers. This article will discuss the 3 most common ways that an organization can be structured, and the benefits and problems of each design in spinal care.
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28323603/how-medicine-may-save-the-life-of-us-immigration-policy-from-clinical-and-educational-encounters-to-ethical-public-policy
#7
Mark G Kuczewski
Medicine has a conceptual contribution to make to the immigration debate. Our nation has been unable to move forward with meaningful immigration reform because many citizens seem to assume that immigrants are in the United States to access benefits to which they are not entitled. In contrast, when medicine encounters undocumented immigrants in the health care or medical education setting, it is obvious that their contributions to our health care system are denied by exclusionary laws. When the system is amended to be inclusive, immigrants become contributors to the systems that they access...
March 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/28323544/host-diet-affects-the-morphology-of-a-butterfly-parasite
#8
Kevin Ming-Kong Hoang, Leiling Tao, Jacobus C de Roode, Mark D Hunter
Understanding host-parasite interactions is essential for ecological research, wildlife conservation and health management. While most studies focus on numerical traits of parasite groups, such as changes in parasite load, less focus is placed on the traits of individual parasites, such as parasite size and shape (parasite morphology). Parasite morphology has significant effects on parasite fitness, such as initial colonization of hosts, avoidance of host immune defenses, and the availability of resources for parasite replication...
March 21, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28323533/success-in-weight-management-among-patients-with-type-2-diabetes-do-perceived-autonomy-support-autonomous-motivation-and-self-care-competence-play-a-role
#9
Anne M Koponen, Nina Simonsen, Sakari B Suominen
Based on self-determination theory (SDT), this study investigated whether the three central SDT variables-perceived autonomy support (from a physician), autonomous motivation and self-care competence-were associated with success in weight management (SWM) among primary care patients with type 2 diabetes when the effect of other important life-context factors was controlled for. Patients participated in a mail survey in 2011. Those who had tried to change their health behavior during the past two years in order to lose weight, either with or without success (n = 1433, mean age 63 years, 50% men), were included in this study...
March 21, 2017: Behavioral Medicine
https://www.readbyqxmd.com/read/28323514/perceptions-of-risks-and-benefits-among-nonprescription-stimulant-consumers-diverters-and-non-users
#10
Brittany A Kinman, Kevin J Armstrong, Kristina B Hood
BACKGROUND: Few studies have examined perceptions of legal and health risks along with the perceived benefits of nonprescription stimulant (NPS) use in college students (e.g., using stimulants such as Ritalin, Vvyanse, Concerta, or Adderall without a prescription). OBJECTIVE: This study sought to better understand how college students perceived legal and health risks, as well as motivations associated with NPS use. The perceived risks and benefits were examined between those involved and those uninvolved...
March 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28323475/universal-mandatory-reporting-policies-and-the-odds-of-identifying-child-physical-abuse
#11
Grace W K Ho, Deborah A Gross, Amie Bettencourt
OBJECTIVES: To examine the relationships between universal mandatory reporting (UMR), child physical abuse reporting, and the moderating effect of UMR on physical abuse report outcomes by report source. METHODS: We used a national data set of 204 414 children reported for physical abuse in 2013 to compare rates of total and confirmed reports by states or territories with and without UMR. We estimated odds and predicted probabilities of confirming a physical abuse report made by professional versus nonprofessional reporters, accounting for the moderating effect of UMR and individual-level characteristics...
March 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28320100/drosophila-melanogaster-a-potential-model-organism-for-identification-of-pharmacological-properties-of-plants-plant-derived-components
#12
REVIEW
Komal Panchal, Anand K Tiwari
Plants/plant-derived components have been used from ancient times to treat/cure several human diseases. Plants and their parts possess several chemical components that play the vital role in the improvement of human health and their life expectancy. Allopathic medicines have been playing a key role in the treatment of several diseases. Though allopathic medicines provide fast relief, long time consumption cause serious health concerns such as hyperallergic reactions, liver damage, etc. So, the study of medicinal plants which rarely cause any side effect is very important to mankind...
March 18, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28319907/the-impact-of-welfare-reform-on-the-health-insurance-coverage-utilization-and-health-of-low-education-single-mothers
#13
Kimberly Narain, Marianne Bitler, Ninez Ponce, Gerald Kominski, Susan Ettner
The Personal Responsibility Work Opportunity and Reconciliation Act (PRWORA) of 1996 imposed time limits on the receipt of welfare cash benefits and mandated cash benefit sanctions for failure to meet work requirements. Many studies examining the health implications of PRWORA have found associated declines in health insurance coverage and healthcare utilization among single mothers but no impact of PRWORA on health outcomes. A limitation of this literature is that most studies cover a time period before time limits were implemented in all states and also before individuals began actually timing out...
March 11, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28319588/physical-activity-and-global-self-worth-in-a-longitudinal-study-of-children
#14
Hudson Reddon, David Meyre, John Cairney
PURPOSE: Physical activity is associated with an array of physical and mental health benefits among children and adolescents. The development of self-worth/self-esteem has been proposed as a mechanism to explain the mental health benefits derived from physical activity. Despite several studies that have analyzed the association between physical activity and self-worth, the results have been inconsistent. It is also uncertain how related physical health measures, such as sedentary behaviour, body composition and fitness influence the relationship between physical activity and self-worth over time...
March 18, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28319492/simulation-faculty-development-a-tiered-approach
#15
Dawn Taylor Peterson, Penni I Watts, Chad A Epps, Marjorie Lee White
Simulation faculty development has become a high priority for the past couple of years because simulation programs have rapidly expanded in health systems and universities worldwide. A formalized, structured model for developing quality facilitators of simulation is helpful to support and sustain this continued growth in the field of simulation. In this article, we present a tiered faculty development plan that has been implemented at a university in the United States and includes the essentials of faculty development...
March 18, 2017: Simulation in Healthcare: Journal of the Society for Simulation in Healthcare
https://www.readbyqxmd.com/read/28319240/two-paradigms-for-endovascular-thrombectomy-after-intravenous-thrombolysis-for-acute-ischemic-stroke
#16
Gaspard Gerschenfeld, Ioan-Paul Muresan, Raphael Blanc, Michael Obadia, Marie Abrivard, Michel Piotin, Sonia Alamowitch
Importance: Intravenous thrombolysis (IVT) followed by mechanical thrombectomy (MT) is recommended to treat acute ischemic stroke (AIS) with a large vessel occlusion (LVO). Most hospitals do not have on-site MT facilities, and most patients need to be transferred secondarily after IVT (drip and ship), which may have an effect on the neurologic outcome. Objective: To compare the functional independence at 3 months between patients treated under the drip-and-ship paradigm and those treated on site (mothership)...
March 20, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28319170/antibody-response-against-phop-efficiently-discriminates-among-healthy-individuals-tuberculosis-patients-and-their-contacts
#17
Aurobind Vidyarthi, Nargis Khan, Tapan Agnihotri, Kaneez F Siddiqui, Girish R Nair, Ashish Arora, Ashok K Janmeja, Javed N Agrewala
Tuberculosis continues to be one of the most devastating global health problem. Its diagnosis will benefit in timely initiation of the treatment, cure and therefore reduction in the transmission of the disease. Tests are available, but none can be comprehensively relied on for its diagnosis; especially in TB-endemic zones. PhoP is a key player in Mycobacterium tuberculosis virulence but nothing has been known about its role in the diagnosis of TB. We monitored the presence of anti-PhoP antibodies in the healthy, patients and their contacts...
2017: PloS One
https://www.readbyqxmd.com/read/28319004/updated-risk-factors-should-be-used-to-predict-development-of-diabetes
#18
Mary Angelyn Bethel, Kristen A Hyland, Antonio R Chacra, Prakash Deedwania, Gregory R Fulcher, Rury R Holman, Trond Jenssen, Naomi S Levitt, John J V McMurray, Eleni Boutati, Laine Thomas, Jie-Lena Sun, Steven M Haffner
AIMS: Predicting incident diabetes could inform treatment strategies for diabetes prevention, but the incremental benefit of recalculating risk using updated risk factors is unknown. We used baseline and 1-year data from the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial to compare diabetes risk prediction using historical or updated clinical information. METHODS: Among non-diabetic participants reaching 1year of follow-up in NAVIGATOR, we compared the performance of the published baseline diabetes risk model with a "landmark" model incorporating risk factors updated at the 1-year time point...
March 2, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28318984/safety-and-efficacy-of-thrombectomy-in-acute-ischaemic-stroke-revascat-1-year-follow-up-of-a-randomised-open-label-trial
#19
Antoni Dávalos, Erik Cobo, Carlos A Molina, Angel Chamorro, M Angeles de Miquel, Luis San Román, Joaquín Serena, Elena López-Cancio, Marc Ribó, Mónica Millán, Xabier Urra, Pere Cardona, Alejandro Tomasello, Carlos Castaño, Jordi Blasco, Lucía Aja, Marta Rubiera, Meritxell Gomis, Arturo Renú, Blanca Lara, Joan Martí-Fàbregas, Brian Jankowitz, Neus Cerdà, Tudor G Jovin
BACKGROUND: The REVASCAT trial and other studies have shown that the neurovascular thrombectomy improves outcomes at 90 days post stroke. However, whether the observed benefit is sustained in the long term remains unknown. We report the results of the prespecified 12-month analysis of the REVASCAT trial. METHODS: Patients with acute ischaemic stroke who could be treated within 8 h of symptom onset were randomly assigned to medical therapy (including intravenous alteplase when eligible) and neurovascular thrombectomy with Solitaire FR or medical therapy alone...
March 16, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28318757/-imputing-missing-data-in-public-health-general-concepts-and-application-to-dichotomous-variables
#20
Gilma Hernández, David Moriña, Albert Navarro
The presence of missing data in collected variables is common in health surveys, but the subsequent imputation thereof at the time of analysis is not. Working with imputed data may have certain benefits regarding the precision of the estimators and the unbiased identification of associations between variables. The imputation process is probably still little understood by many non-statisticians, who view this process as highly complex and with an uncertain goal. To clarify these questions, this note aims to provide a straightforward, non-exhaustive overview of the imputation process to enable public health researchers ascertain its strengths...
March 15, 2017: Gaceta Sanitaria
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