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https://www.readbyqxmd.com/read/27926774/trends-in-palliative-care-use-in-elderly-men-and-women-with-severe-heart-failure-in-the-united-states
#1
Monique R Robinson, Sadeer G Al-Kindi, Guilherme H Oliveira
No abstract text is available yet for this article.
December 7, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27926749/trends-in-palliative-care-use-in-elderly-men-and-women-with-severe-heart-failure-in-the-united-states-reply
#2
Anant Mandawat, Paul A Heidenreich, Deepak L Bhatt
No abstract text is available yet for this article.
December 7, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27926555/avoiding-radical-surgery-in-elderly-patients-with-rectal-cancer-is-cost-effective
#3
Christopher Rao, Arthur Sun Myint, Thanos Athanasiou, Omar Faiz, Antony Paul Martin, Brendan Collins, Fraser McLean Smith
BACKGROUND: Radical surgery is associated with significant perioperative mortality in elderly and comorbid populations. Emerging data suggest for patients with a clinical complete response after neoadjuvant chemoradiotherapy that a watch-and-wait approach may provide equivalent survival and oncological outcomes. OBJECTIVE: The purpose of this study was to compare the cost-effectiveness of watch and wait and radical surgery for patients with rectal cancer after a clinical complete response following chemoradiotherapy...
January 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27925856/clinical-and-economic-impact-of-herpes-zoster-vaccination-in-elderly-in-italy
#4
Sara Boccalini, Cristiano Alicino, Domenico Martinelli, Angela Bechini, Emilia Tiscione, Barbara Pellizzari, Rosa Prato, Giancarlo Icardi, Stefania Iannazzo, Paolo Bonanni
Herpes zoster (HZ) is a very relevant pathology among elderly people (≥ 60 years of age), with a considerable disease burden and loss of quality of life. In the last years a new vaccine against HZ became available in Italy. Therefore, the Italian decision makers are now confronted with the decision whether that vaccination should be implemented. Pharmaco-economic analyses represent useful tools to value the feasibility of new immunization programs and their sustainability. To this aim, an ad hoc population model was developed in order to value the clinical and economic impact of HZ vaccination program for the elderly in Italy...
December 7, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27925855/costs-associated-with-influenza-related-hospitalization-in-the-elderly
#5
Núria Torner, Encarna Navas, Núria Soldevila, Diana Toledo, Gemma Navarro, Aurea Morillo, Maria José Pérez, Angela Domínguez
Seasonal influenza epidemics remain a considerable burden in adults, especially in those at higher risk of complications. The aim of this study was to determine the costs associated with influenza-related hospitalization in patients aged ≥65 years admitted to 20 hospitals from seven Spanish regions during the 2013-14 and 2014-15 influenza seasons. Bivariate analysis was used to compare costs in vaccinated and unvaccinated cases. Costs were calculated according to the Spanish National Health System diagnosis-related group tables for influenza and other respiratory system conditions (GRD 89 and GRD 101)...
December 7, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27925848/hospitalizations-for-pneumococcal-diseases-in-tuscany-from-2002-to-2014-impact-of-universal-pediatric-vaccination-on-the-population
#6
Sara Boccalini, Ornella Varone, Martina Chellini, Luca Pieri, Antonino Sala, Cesare Berardi, Paolo Bonanni, Angela Bechini
Streptococcus pneumoniae is the main causative organism of acute media otitis in children and meningitis and bacterial pneumonia in the community. Since 2008 in Tuscany, central Italy, the pneumococcal conjugate vaccine (7-valent vaccine, switched in 13-valent vaccine in 2010) was actively offered free of charge to all newborns. Aim of the study is to evaluate the impact of pneumococcal paediatric vaccination on the Tuscan population on hospitalizations potentially caused by S. pneumoniae, during pre-vaccination (PVP, 2002-2007) and vaccination period (VP, 2009-2014)...
December 7, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27925845/economic-studies-applied-to-vaccines-against-invasive-diseases-an-updated-budget-impact-analysis-of-age-based-pneumococcal-vaccination-strategies-in-the-elderly-in-italy
#7
Sara Boccalini, Angela Bechini, Roberto Gasparini, Donatella Panatto, Daniela Amicizia, Paolo Bonanni
Many evaluations have been carried out on the economic impact of pneumococcal vaccination in older adults (>64 years of age) in several countries, including Italy. However, these studies did not include the new data on the effectiveness of 13-valent conjugate pneumococcal vaccine (PCV13) in the elderly reported by the CAPiTA Study. The aim of the present study was to update our previous budget impact analysis of multi-cohort PCV13 vaccination in adults in Italy by including new scientific evidence. We also compared single-cohort vaccination strategies per year, in order to identify the cohort with the most favourable economic profile, in the event of the multi-cohort approach not being economically sustainable for the National Health System (NHS)...
December 7, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27925843/incidence-of-herpes-zoster-and-post-herpetic-neuralgia-in-italy-results-from-a-three-years-population-based-study
#8
Cristiano Alicino, Cecilia Trucchi, Chiara Paganino, Ilaria Barberis, Sara Boccalini, Domenico Martinelli, Barbara Pellizzari, Angela Bechini, Andrea Orsi, Paolo Bonanni, Rosa Prato, Stefania Iannazzo, Giancarlo Icardi
Herpes Zoster (HZ) and its main complication, post-herpetic neuralgia (PHN), represent important public health issues because of their relevant burden among older adults. However, data on the epidemiology of HZ and PHN in Italy are very limited. A population-based study was performed by seeking for cases of HZ and PHN, occurred in the period 2013-2015, in the clinical charts of 56 General Practitioners working in four Italian Regions (Liguria, Puglia, Toscana and Veneto). The main objective of the study was to estimate the incidence of HZ and the proportion of PHN (at 1 and 3 months from the onset of HZ; PHN1 and PHN3) among people aged ≥ 50 years...
December 7, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27925710/assessment-of-water-intake-from-food-and-beverages-by-elderly-in-poland
#9
Małgorzata E Drywień, Katarzyna Galon
Background: Fluid intake in elderly is more important than in younger individuals, because compromised homeostatic mechanisms such as loss of the thirst sensation can result in dehydration. Objective: The aim of the present study was the assessment of water intake from food and beverages by free-living elderly in Poland. Materials and Methods: The study was conducted on 138 volunteers (women and men) at the age of 60 to 90, recruited from Warsaw and Płock Universities of the Third Age and different informal groups from the same cities...
2016: Roczniki Państwowego Zakładu Higieny
https://www.readbyqxmd.com/read/27925642/high-complication-rate-in-young-patients-with-high-energy-intertrochanteric-femoral-fractures
#10
Michael H Amini, John J Feldman, John C Weinlein
Although intertrochanteric femoral fractures in elderly patients are common injuries that have been studied extensively, little has been reported about high-energy intertrochanteric fractures in younger patients. This study examined the injury characteristics and outcomes of high-energy intertrochanteric fractures in patients younger than 65 years treated with either sliding hip screws (SHSs) or cephalomedullary nails (CMNs). A total of 37 patients younger than 65 years (mean age, 45 years) with high-energy intertrochanteric fractures and mean follow-up of 34 weeks were identified; 21 patients were treated with SHSs, and 16 patients were treated with CMNs...
December 7, 2016: Orthopedics
https://www.readbyqxmd.com/read/27925597/tackling-missing-data-in-community-health-studies-using-additive-ls-svm-classifier
#11
Guanjin Wang, Zhaohong Deng, Kup-Sze Choi
Missing data is a common issue in community health and epidemiological studies. Direct removal of samples with missing data can lead to reduced sample size and information bias, which deteriorates the significance of the results. While data imputation methods are available to deal with missing data, they are limited in performance and could introduce noises into the dataset. Instead of data imputation, a novel method based on additive least square support vector machine (LS-SVM) is proposed in this paper for predictive modeling when the input features of the model contain missing data...
December 1, 2016: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/27925456/national-trends-in-incidence-and-survival-of-chronic-lymphocytic-leukemia-in-norway-for-1953-2012-a-systematic-analysis-of-population-based-data
#12
Andrea Lenartova, Tom Børge Johannesen, Geir Erland Tjønnfjord
Chronic lymphocytic leukemia is a disease of the elderly, and despite major advances in treatment, remains incurable. The Cancer Registry of Norway has registered data on patients with chronic lymphocytic leukemia since 1953. We aimed to analyze trends in incidence and survival of chronic lymphocytic leukemia in Norway. We identified 7664 patients reported with chronic lymphocytic leukemia to the registry between 1953 and 2012. We gathered information on sex, age at diagnosis, date of death and basis for diagnosis...
December 2016: Cancer Medicine
https://www.readbyqxmd.com/read/27925337/complication-rates-of-catheter-ablation-of-atrial-fibrillation-in-patients-aged-%C3%A2-75-years-versus-75-years-results-from-the-german-ablation-registry
#13
J Moser, S Willems, D Andresen, J Brachmann, L Eckardt, E Hoffmann, K H Kuck, T Lewalter, B Schumacher, S G Spitzer, M Hochadel, J Senges, B A Hoffmann
INTRODUCTION: Despite a rising demand for catheter ablation (CA) of atrial fibrillation (AF) in an elderly population, complication and success rates are not fully elucidated. We sought to compare complication rates of CA of AF in patients ≥ 75 versus < 75 years of age. METHODS AND RESULTS: Patients with symptomatic, drug-refractory AF were prospectively enrolled from January 2007 to 2010 in this multicenter study. A total of 4449 patients, group 1 ≥ 75 years and group 2 < 75 years (n = 227, age 77...
December 7, 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/27925303/pretreatment-neutrophil-lymphocyte-ratio-but-not-platelet-lymphocyte-ratio-has-a-prognostic-impact-in-multiple-myeloma
#14
Yanjie Li, Hujun Li, Wenjing Li, Lijin Wang, Zhiling Yan, Yao Yao, Ruosi Yao, Kailin Xu, Zhenyu Li
BACKGROUND: We evaluated the prognostic significance of neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) in patients with multiple myeloma (MM). METHODS: In total, we retrospectively analyzed 315 newly diagnosed MM patients and calculated NLR and PLR from the complete blood count of the untreated patients. We further assessed the role of pretreatment NLR and PLR on overall survival (OS) and progression-free survival (PFS). RESULTS: Multiple myeloma patients with high NLR (≥2) experienced shorter OS (P=...
December 7, 2016: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/27925147/incidence-risk-factors-and-the-protective-effect-of-high-body-mass-index-against-sarcopenia-in-suburb-dwelling-elderly-chinese-populations
#15
P Han, J Zhao, Q Guo, J Wang, W Zhang, S Shen, X Wang, R Dong, Y Ma, L Kang, L Fu, L Jia, X Han, Z He, Y Bao, L Wang, K Niu
BACKGROUND: Few studies have explored the risk factors of sarcopenia in certain cohorts. The objective of this study was to examine the incidence of sarcopenia and associated factors over a 1-year period in an elderly Chinese suburban population. METHODS: This study was conducted on 356 Chinese suburb-dwelling participants aged ≥60 years, for whom detailed information regarding sociodemographics, behavioral characteristics, and medical conditions had been documented...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27925141/nutritional-interventions-that-slow-the-age-associated-decline-in-renal-function-in-a-canine-geriatric-model-for-elderly-humans
#16
J A Hall, M Yerramilli, E Obare, M Yerramilli, K S Panickar, G Bobe, D E Jewell
OBJECTIVE: To determine the effects of feeding traditional and renal protective foods (RPF) supplemented with functional food bioactives on glomerular filtration rate (GFR), lean body percent (LB%), and selected circulating biomarker and metabolite concentrations in a geriatric dog model. DESIGN: Randomized block design and cross-sectional study. SETTING: Hill's Pet Nutrition, Inc. dog colony. PARTICIPANTS: Eighty-one geriatric dogs (mean age, 10...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27925140/tea-consumption-reduces-the-incidence-of-neurocognitive-disorders-findings-from-the-singapore-longitudinal-aging-study
#17
L Feng, M-S Chong, W-S Lim, Q Gao, M S Nyunt, T-S Lee, S L Collinson, T Tsoi, E-H Kua, T-P Ng
OBJECTIVES: To examine the relationships between tea consumption habits and incident neurocognitive disorders (NCD) and explore potential effect modification by gender and the apolipoprotein E (APOE) genotype. DESIGN: Population-based longitudinal study. SETTING: The Singapore Longitudinal Aging Study (SLAS). PARTICIPANTS: 957 community-living Chinese elderly who were cognitively intact at baseline. MEASUREMENTS: We collected tea consumption information at baseline from 2003 to 2005 and ascertained incident cases of neurocognitive disorders (NCD) from 2006 to 2010...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27925139/association-of-grip-strength-upper-arm-circumference-and-waist-circumference-with-dementia-in-older-adults-of-the-wise-study-a-cross-sectional-analysis
#18
H L Ong, S H S Chang, E Abdin, J A Vaingankar, A Jeyagurunathan, S Shafie, H Magadi, S A Chong, M Subramaniam
OBJECTIVE: We examined the associations of handgrip strength, upper arm circumference, and waist circumference with dementia among Singapore older adults. DESIGN: Cross-sectional epidemiological study. SETTING: Residential homes, day care centres, nursing homes and institutions. PARTICIPANTS: 2,565 men and women aged 60 years and above who participated in the Well-being of the Singapore Elderly (WiSE) study in 2013. MEASUREMENTS: Socio-demographic correlates, dietary habits, health behaviours, grip strength, upper arm circumference, and waist circumference were collected...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27925137/longitudinal-association-between-selenium-levels-and-hypertension-in-a-rural-elderly-chinese-cohort
#19
L Su, Y Jin, F W Unverzagt, C Liang, Y Cheng, A M Hake, D Kuruppu, F Ma, J Liu, C Chen, J Bian, P Li, S Gao
OBJECTIVES: Results from previous studies have been inconsistent on the association between selenium and hypertension, and very few studies on this subject have focused on the elderly population. The purpose of this study is to examine the relationship between selenium level and hypertension in a rural elderly Chinese cohort. DESIGN: A longitudinal study was implemented and data were analyzed using logistic regression models and Cox proportional hazards regression model adjusting for potential confounders...
2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27925136/multidimensional-evaluation-of-endogenous-and-health-factors-affecting-food-preferences-taste-and-smell-perception
#20
D Guido, S Perna, M Carrai, R Barale, M Grassi, M Rondanelli
OBJECTIVE: This study, by taking a holistic approach, investigates the relationships between taste, smell sensitivity and food preference with prognostic (endogenous and health) factors including age, gender, genetic taste markers, body mass, cigarette smoking, and number of drugs used. DESIGN: Cross sectional study. SETTING: Northern Italy. PARTICIPANTS: 203 healthy subjects (160 women/43 men; mean age: 58.2±19.8 years) were examined...
2016: Journal of Nutrition, Health & Aging
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