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AKI epidemiology

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https://www.readbyqxmd.com/read/29321655/evaluation-of-brain-activity-using-near-infrared-spectroscopy-in-inflammatory-bowel-disease-patients
#1
Tatsuo Fujiwara, Soichi Kono, Kyoko Katakura, Kazumichi Abe, Atsushi Takahashi, Naohiko Gunji, Aki Yokokawa, Kazumasa Kawashima, Rieko Suzuki, Akira Wada, Itaru Miura, Hirooki Yabe, Hiromasa Ohira
Depression is implicated as a risk factor for the recurrence of inflammatory bowel disease (IBD). Near-infrared spectroscopy (NIRS) and brain-derived neurotrophic factor (BDNF) are useful tools for evaluation of brain activity and a depressive state, respectively. The aim of this study was to clarify the association between brain activity or depressive symptoms and IBD using NIRS and BDNF. This study included 36 ulcerative colitis (UC) patients, 32 Crohn's disease (CD) patients, and 17 healthy controls (HC)...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29286559/high-incidence-of-acute-kidney-injury-during-chemotherapy-for-childhood-acute-myeloid-leukemia
#2
Liezl Du Plessis, Shahrad Rod Rassekh, Cherry Mammen
BACKGROUND/OBJECTIVES: Childhood acute myeloid leukemia (AML) is a rare and heterogeneous disease. Pediatric data on the epidemiology of acute kidney injury (AKI) in AML are limited. We report on the incidence of AKI in childhood AML and the risk factors associated with AKI episodes. METHODS: A retrospective cohort of 53 patients (≤18 years), with de novo AML, receiving chemotherapy over a 10-year period. All serum creatinine (SCr) levels during therapy-related hospitalizations were assessed to stage AKI episodes as per Kidney Disease: Improving Global Outcomes criteria...
December 29, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29283932/glomerular-filtration-rate-is-unchanged-by-ultramarathon
#3
Wojciech Wołyniec, Wojciech Ratkowski, Katarzyna Kasprowicz, Zbigniew Jastrzębski, Sylwia Małgorzewicz, Konrad Witek, Tomasz Grzywacz, Piotr Żmijewski, Marcin Renke
THE MAIN PROBLEM: Acute kidney injury (AKI) is reported as a common complication of marathon and ultramarathon running. In previous studies AKI was diagnosed on the basis of the creatinine level in serum and estimated glomerular filtration rate (eGFR). In the present study we calculated eGFR and also measured creatinine clearance after every 25 km of a 100 km run. METHODS: 20 healthy, amateur runners (males, mean age 40.75 ± 7.15 years, mean weight 76.87 ± 8.39 kg) took part in a 100 km run on a track...
December 27, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29283473/international-statistical-classification-of-diseases-and-related-health-problems-coding-underestimates-the-incidence-and-prevalence-of-acute-kidney-injury-and-chronic-kidney-disease-in-general-medical-patients
#4
Soe Ko, Sudharsan Venkatesan, Kushma Nand, Vicki Levidiotis, Craig Nelson, Edward Janus
BACKGROUND: The International classification of diseases (ICD) code is frequently used to identify renal impairment in epidemiologic research. However, Australian studies examining accuracy of this administrative data in coding kidney injury are lacking. AIMS: To compare the ICD 10 coding with the Kidney Disease: Improving Global Outcomes (KDIGO) criteria in diagnosing Acute Kidney Injury (AKI) and/or Chronic Kidney Disease (CKD). METHODS: A retrospective study of 325 patients admitted to General Medicine during January 2012 was performed...
December 28, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/29274596/pragmatic-studies-for-acute-kidney-injury-consensus-report-of-the-acute-disease-quality-initiative-adqi-19-workgroup
#5
Zhiyong Peng, Kaijiang Yu, Marlies Ostermann, XiuMing Xi, Raymond Hsu, Jean-Louis Vincent, John R Prowle, Bin Du, Martin Gallagher, Changsong Wang, Raghavan Murugan, Haibo Qiu, Thomas Rimmelé, Jianguo Li, Lui G Forni, Kianoush Kashani, Claudio Ronco, John A Kellum
PURPOSE: Acute kidney injury (AKI) has become a major medical and financial burden in China along with the rest of the world. There have been considerable advances in the understanding of the epidemiology and pathogenesis of AKI. However, there is no consensus regarding the optimal care for patients. The Acute Disease Quality Initiative (ADQI) 19 meeting focused on identifying and designing relevant and achievable AKI-related studies in China. MATERIALS & METHODS: The working group developed a list of preliminary questions and objectives and performed analysis of the existing literature...
December 12, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/29248148/acute-kidney-injury-in-pediatric-patients
#6
REVIEW
David M Kwiatkowski, Scott M Sutherland
Acute kidney injury (AKI) is highly prevalent among hospitalized children, especially those who are critically ill. The incorporation of pediatric elements into consensus definitions has led to a greater understanding of pediatric AKI epidemiology, risk factors, and outcomes. The best available data suggest that AKI occurs in 5% and 27% of non-critically ill and critically ill children, respectively. Additionally, AKI and fluid overload are independently associated with worse outcomes including mortality. Currently, the diagnosis of AKI relies upon urine output and creatinine measurements, both of which pose unique problems in children...
September 2017: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/29248147/sequelae-of-aki
#7
REVIEW
Samir S Patel, Carlos E Palant, Vrinda Mahajan, Lakhmir S Chawla
Large epidemiologic studies in a variety of patient populations reveal increased morbidity and mortality that occur months to years after an episode of acute kidney injury (AKI). Even milder forms of AKI have increased associated morbidity and mortality. Residual confounding may account for these findings, but considering the huge number of individuals afflicted with AKI, the sequelae of AKI may be a very large public health burden. AKI may simply be a marker for increased risk, but there is increasing evidence that it is part of the causal pathway to chronic kidney disease...
September 2017: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/29248137/epidemiology-of-cardiac-surgery-associated-acute-kidney-injury
#8
REVIEW
Eric A J Hoste, Wim Vandenberghe
Acute kidney injury (AKI) is defined by the KDIGO definition into 3 stages on basis of an increase in serum creatinine or a period of oliguria. AKI is defined as rapid reversal when the episode is 48 h or less. When AKI persists for 7 days or longer, the term acute kidney disease is used. Subclinical AKI is defined by increased concentration of an AKI biomarker, without meeting the KDIGO definition for AKI. In contrast to this, functional AKI is defined by the KDIGO definition, wherein the AKI biomarker concentration is not increased...
September 2017: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/29230707/acute-kidney-injury-after-abdominal-aortic-aneurysm-repair-current-epidemiology-and-potential-prevention
#9
Liesa Zabrocki, Frank Marquardt, Klaus Albrecht, Stefan Herget-Rosenthal
PURPOSE: Acute kidney injury (AKI) is a severe complication after infrarenal abdominal aortic aneurysm (iAAA) repair. Little data are available whether endovascular aneurysm (EVAR) or open aortic repair (OAR) differs with respect to AKI frequency and severity, consecutive development of chronic kidney disease (CKD) and potentially preventable and modifiable risk factors of AKI. PATIENTS AND METHODS: We assessed AKI rates, AKI stages and CKD applying current, complete definitions from the kidney disease improving global outcomes initiative in propensity-score-matched cohorts of all patients with elective and urgent iAAA repair at our institution from 2007 to 2011...
December 11, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/29229169/acute-kidney-injury-in-children
#10
REVIEW
Scott M Sutherland, David M Kwiatkowski
Acute kidney injury (AKI) has become one of the more common complications seen among hospitalized children. The development of a consensus definition has helped refine the epidemiology of pediatric AKI, and we now have a far better understanding of its incidence, risk factors, and outcomes. Strategies for diagnosing AKI have extended beyond serum creatinine, and the most current data underscore the diagnostic importance of oliguria as well as introduce the concept of urinary biomarkers of kidney injury. As AKI has become more widespread, we have seen that it is associated with a number of adverse consequences including longer lengths of stay and greater mortality...
November 2017: Advances in Chronic Kidney Disease
https://www.readbyqxmd.com/read/29215080/risk-predictors-and-outcomes-of-acute-kidney-injury-in-patients-admitted-to-intensive-care-units-in-egypt
#11
Samar Abd ElHafeez, Giovanni Tripepi, Robert Quinn, Yasmine Naga, Sherif Abdelmonem, Mohamed AbdelHady, Ping Liu, Matthew James, Carmine Zoccali, Pietro Ravani
Epidemiology of acute kidney injury (AKI) in developing countries is under-studied. We evaluated the risk and prognosis of AKI in patients admitted to intensive care units (ICUs) in Egypt. We recruited consecutive adults admitted to ICUs in Alexandria Teaching Hospitals over six months. We used the KDIGO criteria for AKI. We followed participants until the earliest of ICU discharge, death, day 30 from entry or study end. Of the 532 participants (median age 45 (Interquartile range [IQR]: 30-62) years, 41.7% male, 23...
December 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29212494/epidemiology-and-outcomes-of-children-with-renal-failure-in-the-pediatric-ward-of-a-tertiary-hospital-in-cameroon
#12
Marie Patrice Halle, Carine Tsou Lapsap, Esther Barla, Hermine Fouda, Hilaire Djantio, Beatrice Kaptue Moudze, Christophe Adjahoung Akazong, Eugene Belley Priso
BACKGROUND: Pediatric nephrology is challenging in developing countries and data on the burden of kidney disease in children is difficult to estimate due to absence of renal registries. We aimed to describe the epidemiology and outcomes of children with renal failure in Cameroon. METHODS: We retrospectively reviewed 103 medical records of children from 0 to 17 years with renal failure admitted in the Pediatric ward of the Douala General Hospital from 2004 to 2013...
December 6, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/29176313/acute-kidney-injury-following-acute-ischemic-stroke-and-intracerebral-hemorrhage-a-meta-analysis-of-prevalence-rate-and-mortality-risk
#13
Andrés Zorrilla-Vaca, Wendy Ziai, E Sander Connolly, Romer Geocadin, Richard Thompson, Lucia Rivera-Lara
BACKGROUND: The epidemiology of acute renal dysfunction after stroke is routinely overlooked following stroke events. Our aim in this meta-analysis is to report the prevalence of acute kidney injury (AKI) following acute stroke and its impact on mortality. METHODS: A systematic literature search was performed on PubMed, EMBASE and Google Scholar for observational studies examining the prevalence and mortality risk of stroke patients with AKI as a complication. The pooled prevalence rates and odds ratios for mortality risk were calculated using subgroup analyses between the stroke subtypes: acute ischemic stroke (AIS) and intracerebral hemorrhage (ICH)...
November 24, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/29169177/acute-kidney-injury-in-elderly-population-a-prospective-observational-study
#14
Cássia Gomes da Silveira Santos, Rafael Fernandes Romani, Ricardo Benvenutti, João Otávio Ribas Zahdi, Miguel Carlos Riella, Marcelo Mazza do Nascimento
BACKGROUND/AIMS: Acute kidney injury (AKI) has been reported as a recognized condition among the elderly population; however, its clinical epidemiology is still poorly evaluated. We propose to evaluate the epidemiological profile of AKI in hospitalized elderly patients and the variables associated with renal replacement therapy (RRT) dependency at discharge after an episode of AKI. METHODS: This prospective observational study enrolled 286 elderly patients (aged ≥60 years), who had a diagnosis of AKI and were admitted to a tertiary care hospital...
November 23, 2017: Nephron
https://www.readbyqxmd.com/read/29155805/epidemiology-and-outcomes-of-community-acquired-and-hospital-acquired-acute-kidney-injury-in-children-and-adolescents
#15
Chien-Ning Hsu, Hsiao-Ling Chen, You-Lin Tain
BACKGROUND: Hospital-acquired acute kidney injury (HA-AKI) is associated with an increased risk of childhood mortality; however, only a few studies have addressed community-acquired AKI (CA-AKI). METHODS: AKI Network classification was used to assess community- and hospital-acquired AKI, 2010-2014. Patients with CA-AKI who were admitted to an inpatient setting were categorized as CAA-AKI. CANA-AKI was for CA-AKI not admitted to inpatient care. Epidemiology, factors associated with AKI, in-hospital outcomes were assessed for variation...
November 20, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29151282/epidemiology-and-impact-of-bloodstream-infections-among-kidney-transplant-recipients-a-retrospective-single-center-experience
#16
Ali M Shendi, Gabriel Wallis, Helena Painter, Mark Harber, Sophie Collier
BACKGROUND: Bloodstream infections (BSI) represent an important source of morbidity and mortality, as well as an increasing therapeutic challenge, among solid organ transplant recipients. Understanding the epidemiological and microbiological characteristics of BSI following renal transplantation is paramount to the implementation of appropriate preventative and therapeutic measures. METHODS: We conducted a retrospective review of all BSI episodes occurring between July 2009 and April 2016 in adult patients, who received a renal transplant at Royal Free London hospital...
November 19, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29136724/-expert-consensus-for-the-diagnosis-and-treatment-of-patients-with-renal-impairment-of-multiple-myeloma
#17
(no author information available yet)
Renal impairment (RI) is a common complication of multiple myeloma (MM), which is presented as chronic kidney disease (CKD) or acute kidney injury (AKI). The typical pathological feature is cast nephropathy. Presently international system staging (ISS) is used in evaluating MM. Although the classic Durie-Salmon staging system could be still used in clinical practice, it may miss out some patients with renal impairment. For evaluations of RI in MM patients with CKD, it's recommended to assess the estimated glomerular filtration rate (eGFR) by creatinine based formula CKD-epidemiology collaboration (EPI) or modification of diet in renal disease(MDRD) and to stage the renal injuries according to 2013 Kidney Disease Improving Global Outcomes (KDIGO) CKD guidelines...
November 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29124867/acute-kidney-injury-in-critically-ill-surgical-patients-epidemiology-risk-factors-and-outcomes
#18
Konlawij Trongtrakul, Chaiwut Sawawiboon, Amanda Y Wang, Anusang Chitsomkasem, Ploynapas Limphunudom, Sathit Kurathong, Surasee Prommoon, Thananda Trakarnvanich, Nattachai Srisawat
AIM: Acute kidney injury (AKI) is one of the most serious complications seen in intensive care units (ICUs). However, its epidemiology, risk factors and clinical outcomes in surgical critically ill patients remains unclear. METHODS: A prospective cohort study was conducted in surgical intensive care unit (ICU) of the university hospital in Bangkok, Thailand. AKI was diagnosed according to the KDIGO 2012 criteria. RESULTS: A total of 189 of the 400 patients enrolled in our study developed AKI (47...
November 10, 2017: Nephrology
https://www.readbyqxmd.com/read/29092921/contrast-induced-acute-kidney-injury-and-mortality-in-st-elevation-myocardial-infarction-treated-with-primary-percutaneous-coronary-intervention
#19
Johanne Silvain, Lee S Nguyen, Vincent Spagnoli, Mathieu Kerneis, Paul Guedeney, Nicolas Vignolles, Kristel Cosker, Olivier Barthelemy, Claude Le Feuvre, Gérard Helft, Jean-Philippe Collet, Gilles Montalescot
OBJECTIVES: Contrast-induced acute kidney injury (CI-AKI) is a common and potentially severe complication in patients with ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). There is no consensus on the best definition of CI-AKI to identify patients at risk of haemodialysis or death. The objective of this study was to assess the association of CI-AKI, using four definitions, on inhospital mortality, mortality or haemodialysis requirement over 1-year follow-up, in patients with STEMI treated with pPCI...
November 1, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29042465/thrombotic-microangiopathy-and-the-kidney
#20
Vicky Brocklebank, Katrina M Wood, David Kavanagh
Thrombotic microangiopathy can manifest in a diverse range of diseases and is characterized by thrombocytopenia, microangiopathic hemolytic anemia, and organ injury, including AKI. It can be associated with significant morbidity and mortality, but a systematic approach to investigation and prompt initiation of supportive management and, in some cases, effective specific treatment can result in good outcomes. This review considers the classification, pathology, epidemiology, characteristics, and pathogenesis of the thrombotic microangiopathies, and outlines a pragmatic approach to diagnosis and management...
October 17, 2017: Clinical Journal of the American Society of Nephrology: CJASN
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