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ultrasonography and coronary artery disease

Jack H Boyd, Vedant S Pargaonkar, David H Scoville, Ian S Rogers, Takumi Kimura, Shigemitsu Tanaka, Ryotaro Yamada, Michael P Fischbein, Jennifer A Tremmel, Robert Scott Mitchell, Ingela Schnittger
BACKGROUND: Left anterior descending artery myocardial bridges (MBs) range from clinically insignificant incidental angiographic findings to a potential cause of sudden cardiac death. Within this spectrum, a group of patients with isolated, symptomatic, and hemodynamically significant MBs despite maximally tolerated medical therapy exist for whom the optimal treatment is controversial. We evaluated supraarterial myotomy, or surgical unroofing, of the left anterior descending MBs as an isolated procedure in these patients...
October 1, 2016: Annals of Thoracic Surgery
Mineto Ohta, Chikashi Nakanishi, Naoki Kawagishi, Yasuyuki Hara, Kai Maida, Toshiaki Kashiwadate, Koji Miyazawa, Satoru Yoshida, Shigehito Miyagi, Yukihiro Hayatsu, Shunsuke Kawamoto, Yasushi Matsuda, Yoshinori Okada, Yoshikatsu Saiki, Noriaki Ohuchi
BACKGROUND: Recurrent hepatocellular carcinoma accompanied by a right atrial tumor thrombus is rare. No standard treatment modality has been established. Surgical treatment may be the only curative treatment; however, surgery has been considered high risk. We herein describe a patient who underwent resection of a recurrent right atrial tumor thrombus under normothermic cardiopulmonary bypass on a beating heart. CASE PRESENTATION: A 60-year-old man underwent a right hepatectomy for hepatocellular carcinoma with diaphragm invasion...
December 2016: Surgical Case Reports
Anil Avci, Serdar Fidan, Mehmet Mustafa Tabakçı, Cuneyt Toprak, Elnur Alizade, Emrah Acar, Emrah Bayam, Muhammet Tellice, Abdurrahman Naser, Ramazan Kargın
BACKGROUND AND OBJECTIVES: The aim of this study was to evaluate the association between the extent of coronary artery disease assessed by the Gensini score and/or the SYNTAX score and the significant carotid stenosis in patients undergoing coronary artery bypass grafting (CABG). SUBJECTS AND METHODS: A total of 225 patients who had carotid doppler ultrasonography prior to CABG were included retrospectively. Significant coronary artery disease was assumed as a lumen diameter stenosis of ≥50% in any of the major epicardial coronary arteries...
September 2016: Korean Circulation Journal
Shui-Xian Du, Lin-Lin Lu, Yang Liu, Quan-Jiang Dong, Shi-Ying Xuan, Yong-Ning Xin
BACKGROUND: Cardiovascular events are an independent risk factor for nonalcoholic fatty liver disease (NAFLD), which is the leading cause of mortality in NAFLD patients. Several recent studies demonstrated that adiponectin (Ad) polymorphisms were involved in the progression of NAFLD and coronary artery disease (CAD). However, reports on the association between Ad polymorphisms and the risk of developing CAD in NAFLD patients are lacking in a Northern Han Chinese population. OBJECTIVES: The present study was designed to evaluate the association between Ad gene polymorphisms (rs266729 and rs2241766) and the risk of developing CAD in Northern Han Chinese patients with NAFLD...
July 2016: Hepatitis Monthly
Ahmed Al-Mamary, Filippo Zilio, Massimo Napodano
Optimal management of multivessel coronary artery disease can be complex. We report a 67-year-old male patient who was admitted to the Padua University Hospital, Padua, Italy, in 2014 with a non-ST-elevation myocardial infarction. Coronary angiography showed diffuse multiple sub-occlusive lesions of the proximal and distal left coronary vessels involving a long segment of the vessel. On intravascular ultrasonography (IVUS), the left main artery was moderately diseased with critically stenotic and calcified branch ostia...
August 2016: Sultan Qaboos University Medical Journal
Zuhal Caliskan, Nursen Keles, Resul Kahraman, Kamil Özdil, Vildan Karagoz, Feyza Aksu, Gonul Aciksari, Yusuf Yilmaz, Seref Kul, Mustafa Caliskan
Crohn's Disease [CD] is one of the Inflammatory Bowel Diseases that are chronic relapsing inflammatory diseases. Despite the major affected organ is intestine in CD, extra intestinal organs and tissues including cardiovascular system are also affected. Several studies have demonstrated that CD patients may have a higher risk of advancing atherosclerosis. The microvascular endothelial dysfunction plays an essential role for developing coronary atherosclerosis. Microvascular structural abnormalities in the retinal circulation may predict macrovascular events such as stroke and coronary heart disease...
November 2016: International Journal of Cardiovascular Imaging
M Szymczak, J Kluz, R Małecki, E Wątorek, M Obremska, M Głuszek, M Klinger, M Boratyńska
BACKGROUND: The aim of this study was to compare the effect of immunosuppressive regimens using either mammalian target of rapamycin inhibitors (mTORi) or calcineurin inhibitors (CNI) on the risk of atherosclerosis in renal transplant patients. MATERIALS AND METHODS: The study involved a group of 24 recipients treated with mTORi (mTORi group) and a group of 20 recipients treated with immunosuppressive regimen based on CNI (CNI group). Laboratory and clinical markers of cardiovascular risk in both groups were investigated...
June 2016: Transplantation Proceedings
M Dudziak, D Rawicz-Zegrzda, M Jankowska, A Dębska-Ślizień, Z Wołyniec, B Rutkowski
BACKGROUND: Cardiovascular complications, including coronary artery disease and chronic heart failure, are the leading causes of death in patients with chronic kidney disease. New echocardiographic techniques, such as tissue Doppler imaging (TDI) with strain and strain rate, are noninvasive, easy-to-perform methods of the estimation of left ventricular (LV) systolic and diastolic function. The aim of the study was to analyze the utility of new noninvasive methods of cardiovascular risk stratification in patients after kidney transplantation...
June 2016: Transplantation Proceedings
Eisuke Amiya, Masafumi Watanabe, Shogo Watanabe, Munenori Takata, Issei Komuro
PURPOSE: The aim of this study is to investigate the relationship between arterial pulse amplitude change under increased shear stress and the presence of ischemic heart disease (IHD). METHODS: This study comprised 31 subjects, including 14 subjects with IHD. We investigated the change in brachial artery pulse amplitude during flow-mediated dilation (FMD) using ultrasonography. RESULTS: The arterial pulse amplitude increased during FMD in 19 subjects, whereas it decreased in 12 subjects...
2016: SpringerPlus
Mohamed B Elshazly, Stephen J Nicholls, Steven E Nissen, Julie St John, Seth S Martin, Steven R Jones, Renato Quispe, Brian Stegman, Samir R Kapadia, E Murat Tuzcu, Rishi Puri
The total cholesterol to high-density lipoprotein cholesterol (TC/HDL-C) ratio may quantify atherogenic lipoproteins beyond low-density lipoprotein cholesterol (LDL-C), non-HDL-C and apolipoprotein B (apoB). We analyzed pooled data from 9 trials involving 4,957 patients with coronary artery disease undergoing serial intravascular ultrasonography to assess changes in percent atheroma volume (ΔPAV) and 2-year major adverse cardiovascular event (MACE) rates when TC/HDL-C levels were discordant with LDL-C, non-HDL-C, and apoB...
September 1, 2016: American Journal of Cardiology
Sanne M Dietz, Carline E Tacke, Eric de Groot, Irene M Kuipers, Barbara A Hutten, Taco W Kuijpers
BACKGROUND: Kawasaki disease (KD) is a pediatric vasculitis with coronary artery aneurysm (CAA) as a major complication. Controversy exists about cardiovascular risk later in life. The aim of our study was to evaluate whether KD patients are at increased risk, as assessed by carotid intima-media thickness (cIMT). METHODS AND RESULTS: We measured cIMT over 15 years by B-mode ultrasonography in KD patients during follow-up and in unaffected controls (mostly siblings)...
July 2016: Journal of the American Heart Association
Bong-Joon Kim, Sang-Hoon Cho, Kyoung-Im Cho, Hyun-Su Kim, Jung-Ho Heo, Tae-Joon Cha
BACKGROUND: Neutrophil-to-lymphocyte ratio (NLR) has recently emerged as a new important inflammatory marker for predicting cardiovascular events. This study aimed to evaluate the combined impact of NLR and type 2 diabetes mellitus (T2DM) on significant coronary artery disease (CAD) and carotid artery atherosclerosis. METHODS: This study includes a total of 828 patients evaluated by coronary angiography and carotid ultrasonography. Significant CAD was defined as at least one vessel with stenosis greater than 50%...
June 2016: Journal of Cardiovascular Ultrasound
Mariko Takeuchi, Kozue Saito, Katsufumi Kajimoto, Kazuyuki Nagatsuka
INTRODUCTION: Spontaneous vasoconstriction of the extracranial internal carotid artery (SVEICA) is a rare cause of cerebral infarction. Most patients with SVEICA suffer recurrent attacks of vasoconstriction. The standard treatment for this condition has not been established and its long-term prognosis is unclear. CASE REPORT: A 25-year-old man with a history of refractory vasospasm angina presented with transient alternating hemiplegia in both the right and left side...
July 2016: Neurologist
Jacob C Jentzer, Casey M Clements, R Scott Wright, Roger D White, Allan S Jaffe
Cardiac arrest is a common and lethal condition frequently encountered by emergency medicine providers. Resuscitation of persons after cardiac arrest remains challenging, and outcomes remain poor overall. Successful resuscitation hinges on timely, high-quality cardiopulmonary resuscitation. The optimal method of providing chest compressions and ventilator support during cardiac arrest remains uncertain. Prompt and effective defibrillation of ventricular arrhythmias is one of the few effective therapies available for treatment of cardiac arrest...
June 16, 2016: Annals of Emergency Medicine
Johannes Lammer, Marc Bosiers, Koen Deloose, Andrej Schmidt, Thomas Zeller, Florian Wolf, Wouter Lansink, Antoine Sauguet, Frank Vermassen, Geert Lauwers, Dierk Scheinert, Jeffrey J Popma, Robert McGreevy, Richard Rapoza, Lewis B Schwartz, Michael R Jaff
OBJECTIVES: This is the first-in-human study of a drug-eluting bioresorbable vascular scaffold (BVS) for treatment of peripheral artery disease (PAD) involving the external iliac artery (EIA) and superficial femoral artery (SFA). BACKGROUND: Drug-eluting BVS has shown promise in coronary arteries. METHODS: The ESPRIT BVS system is a device-drug combination consisting of an everolimus-eluting poly-l-lactide scaffold. Safety and performance were evaluated in 35 subjects with symptomatic claudication...
June 13, 2016: JACC. Cardiovascular Interventions
Benoy N Shah, Roxy Senior
The incidence of significant obesity is rising across the globe. These patients often have a clustering of cardiovascular risk factors and are frequently referred for noninvasive cardiac imaging tests. Stress echocardiography (SE) is widely used for assessment of patients with known or suspected coronary artery disease (CAD), but its clinical utility in morbidly obese patients (in whom image quality may suffer due to body habitus) has been largely unknown. The recently published Stress Ultrasonography in Morbid Obesity (SUMO) study has shown that SE, when performed appropriately with ultrasound contrast agents (whether performed with physiological or pharmacological stress), has excellent feasibility and appropriately risk stratifies morbidly obese patients, including identification of patients who require revascularization...
June 2016: Echo Research and Practice
Meliza Goi Roscani, Gustavo N Augusto, Tainá F C Valadão, Jonas A Araújo, Juliana C Duarte, Juliana I F Gobbi, Liciana V A Silveira, Regina C Coneglian, Daniele A Rossi, Silméia G Zanati, Beatriz B Matsubara, João C Hueb
BACKGROUND: Coronary artery disease is present in at least 30% of patients with degenerative aortic stenosis (AS). Atherosclerosis also performs an important role in the progression of AS, because of the similarities of pathological mechanisms in both conditions. The electrocardiogram (EKG) strain pattern is associated with structural myocardial change and subendocardial ischemia and has been worldwide used as a marker of AS severity. We hypothesized that EKG strain pattern would be a marker of atherosclerosis as well in AS patients...
August 2016: Annals of Vascular Surgery
Li-Hui Yan, Biao Mu, Yue Guan, Xinyu Liu, Nan Zhao, Da Pan, Shao-Zhen Wang
AIMS/INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder of the liver. The relationship between NAFLD and type 2 diabetes remains largely unknown. The aim of the present study was to determine the incidence of complications arising from the interaction between NAFLD and type 2 diabetes. MATERIALS AND METHODS: A total of 212 individuals with type 2 diabetes were included in the study. The presence of NAFLD was determined in individuals using abdominal ultrasonography for the diagnosis of fatty liver disease...
March 19, 2016: Journal of Diabetes Investigation
George Hahalis, Evangelia Zacharioglou, Ioanna Xanthopoulou, Ioanna Koniari, Chistina Kalogeropoulou, Irene Tsota, Aspasia Rigopoulou, Athanasios Diamantopoulos, Vasilios Gkizas, Periklis Davlouros, Karolina Akinosoglou, Marianna Leopoulou, Charalampos Gogos, Dimitrios Alexopoulos
BACKGROUND: Thalassemic patients demonstrate an increased rate of extracardiac vascular complications and increased carotid wall intima-media thickness (cIMT), but very low prevalence of coronary artery disease (CAD). We investigated the atheroma burden by assessing the coronary artery calcium (CAC) and cIMT in these patients. METHODS: We examined 37 patients with β-thalassemia and 150 healthy control volunteers with multi-detector computer tomography (CT) and ultrasonography to determine CAC score and cIMT, respectively...
February 2016: Journal of Geriatric Cardiology: JGC
Yuki Kawano, Masao Takemoto, Takahiro Mito, Hiroko Morisaki, Atsushi Tanaka, Yuka Sakaki, Atsutoshi Matsuo, Kentaro Abe, Satoru Hida, Kumiko Mukae, Teiji Okazaki, Kei-Ichiro Tayama, Toyoshi Inoguchi, Kiyonobu Yoshitake, Ken-Ichi Kosuga
BACKGROUND: The number of patients with type 2 diabetes mellitus (T2DM) continues to increase all over the world. Cardiovascular disease (CVD), especially coronary artery disease (CAD), is a major cause of the morbidity and mortality in patients with T2DM. The prognosis of patients with silent myocardial ischemia (SMI) is worse than that in those without. METHODS AND RESULTS: Thus, to assess how many patients with SMI existed among those patients, CVD screening tests were performed in 128 asymptomatic patients with T2DM without previous histories of CVD...
August 1, 2016: International Journal of Cardiology
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