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ultrasonography and coronary artery disease

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https://www.readbyqxmd.com/read/29688308/visit-to-visit-cholesterol-variability-correlates-with-coronary-atheroma-progression-and-clinical-outcomes
#1
Donald Clark, Stephen J Nicholls, Julie St John, Mohamed B Elshazly, Samir R Kapadia, E Murat Tuzcu, Steven E Nissen, Rishi Puri
Aims: Utilizing serial intravascular ultrasonography (IVUS), we aimed to exam the association of intra-individual lipid variability, coronary atheroma progression, and clinical outcomes. Methods and results: We performed a post hoc patient-level analysis of nine clinical trials involving 4976 patients with coronary artery disease who underwent serial coronary IVUS in the setting of a range of medical therapies. We assessed the associations between progression in percent atheroma volume (ΔPAV), clinical outcomes, and visit-to-visit lipid variability including low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), non-HDL-C, total cholesterol (TC)/HDL-C, and apolipoprotein B (ApoB)...
April 21, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29664811/assessment-of-endothelium-independent-vasodilation-from-methodology-to-clinical-perspectives
#2
Tatsuya Maruhashi, Yasuki Kihara, Yukihito Higashi
: Vascular response to exogenously administered nitroglycerine, an index of endothelium-independent vasodilation, has been used as a control test for the assessment of endothelium-dependent vasodilation (endothelial function) in humans. However, evidence has been accumulating that not only endothelium-dependent vasodilation but also endothelium-independent vasodilation per se is impaired in individuals with cardiovascular risk factors and cardiovascular disease. Impaired endothelium-independent vasodilation is associated with structural vascular alterations and alterations in vascular smooth muscle cells...
April 16, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29622968/atherosclerosis-in-chronic-hepatitis-c-virus-patients-with-and-without-liver-cirrhosis
#3
Ashraf Abd El-Khalik Barakat, Fatma Mohammad Nasr, Amna Ahmed Metwaly, Sherif Morsy, Mervat Eldamarawy
Background: Chronic Hepatitis C virus (HCV) infection and liver cirrhosis may be associated with atherosclerosis and coronary artery disease (CAD). There are two phases to atherosclerosis, Subclinical and Clinical. Assessment of atherosclerosis may be started at its Subclinical phase by the evaluation of Epicardial Fat Thickness (EpFT) and Carotid Intima Thickness (CIMT). Aim of the study: The aim of the study was to evaluate Clinical and Subclinical atherosclerosis in chronic HCV patients with and without liver cirrhosis by evaluating CIMT and EpFT and correlating the results with Child-Pugh functional scoring of cirrhosis as well as with ultrasound and laboratory parameters that define the severity of liver disease...
June 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29618695/clinical-impact-of-the-ankle-brachial-index-in-patients-undergoing-successful-percutaneous-coronary-intervention
#4
Seiichi Hiramori, Yoshimitsu Soga, Norihiko Kamioka, Takashi Miura, Tatsuki Doijiri, Shinichi Shirai, Kenji Ando
BACKGROUND: Several studies have reported a relationship between clinical outcomes and the ankle-brachial index (ABI) in different populations. However, the relationship in Japanese patients or in patients undergoing percutaneous coronary intervention (PCI) has not been examined well.Methods and Results:The subjects were 1,857 patients who underwent PCI from July 2007 to May 2010 and in whom the carotid and renal arteries and abdominal aorta were examined simultaneously by ultrasonography and ABI...
April 4, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29603377/lipoprotein-a-level-associates-with-coronary-artery-disease-rather-than-carotid-lesions-in-patients-with-familial-hypercholesterolemia
#5
Di Sun, Bing-Yang Zhou, Xi Zhao, Sha Li, Cheng-Gang Zhu, Yuan-Lin Guo, Ying Gao, Na-Qiong Wu, Geng Liu, Qian Dong, Jian-Jun Li
BACKGROUND: Lipoprotein(a) [Lp(a)] level is a novel risk factor for atherosclerotic cardiovascular disease in patients with familial hypercholesterolemia (FH), while its impact on the different sites of arteries remains undetermined. We aim to examine the associations of Lp(a) levels with coronary and carotid atherosclerosis in patients with heterozygous FH (HeFH). METHODS: A total of 148 patients with HeFH who have received carotid ultrasonography and coronary angiography due to chest pain were enrolled...
March 30, 2018: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29565984/severity-of-nonalcoholic-fatty-liver-disease-is-associated-with-subclinical-cerebro-cardiovascular-atherosclerosis-risk-in-korean-men
#6
Jung Eun Lee, Yong Jae Lee, Soo Yoon Chung, Hee Woo Cho, Byoung Jin Park, Dong Hyuk Jung
BACKGROUND: No studies have reported the relationship between nonalcoholic fatty liver disease (NAFLD) and concurrent cerebral artery and coronary artery atherosclerosis simultaneously. We aimed at determining whether NAFLD, as assessed by ultrasound, is associated with subclinical cerebro-cardio vascular atherosclerosis (CCVA) by multidetector-row computed tomography (MDCT), and high resolution-magnetic resonance angiography (HR-MRA). This cross-sectional study included men in the general Korean population aged 20-70 years...
2018: PloS One
https://www.readbyqxmd.com/read/29561732/the-severity-of-coronary-artery-disease-was-not-associated-with-non-alcoholic-fatty-liver-disease-in-a-series-of-264-non-diabetic-patients-who-underwent-coronary-angiography
#7
Taraneh Faghihi Langroudi, Habib Haybar, Saeed Alipour Parsa, Mohamad Mahjoorian, Isa Khaheshi, Mohammadreza Naderian
BACKGROUND: It is now suggested an association between non-alcoholic fatty liver disease (NAFLD) and the occurrence of coronary artery disease even in non-diabetic patients. We will determine the rate of NAFLD and its main determinants in non-diabetic patients undergoing coronary angiography. METHODS: This cross-sectional study was accomplished on 264 patients who were candidates for coronary angiography during the year 2016. Coronary angiography has been done to depict the presence or absence of coronary involvement, and the severity of coronary artery disease by determining the number of vessels involved and also the SYNTAX score...
March 19, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/29541613/recent-updates-on-echocardiography-and-ultrasound-for-kawasaki-disease-beyond-the-coronary-artery
#8
REVIEW
Nobutaka Noto, Akiko Komori, Mamoru Ayusawa, Shori Takahashi
Kawasaki disease (KD) is a systemic vasculitis with a predilection for damage to the coronary arteries. In the acute phase, clinical decision making for KD relies on the measurements of the coronary z-score obtained by 2-dimensional echocardiography (2DE). In the convalescent phase, KD patients with coronary artery abnormalities (CAAs) eventually show arteriosclerotic vascular remodeling characterized by marked intimal proliferation and neoangiogenesis after KD vasculitis, which often induces myocardial ischemia...
February 2018: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/29536281/there-is-a-significant-relationship-between-morning-blood-pressure-surge-and-increased-abdominal-aortic-intima-media-thickness-in-hypertensive-patients
#9
Ayse Selcan Koc, Ferıde Fatma Gorgulu, Yurdaer Donmez, Yahya Kemal Icen
PURPOSE: There are limited data about increased aortic intima-media thickness (A-IMT) in the presence of subclinical target organ damage in hypertensive (HT) patients. In this study, we aimed to determine the frequency of increased A-IMT, the parameters determining increased A-IMT, and the relationship between increased A-IMT and other vascular IMT measurements. MATERIALS AND METHODS: We prospectively included 265 patients (mean age 54.1 ± 10.6 years, male/female 91/174) with essential HT...
March 13, 2018: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29514148/the-relationship-between-carotid-and-femoral-artery-intima-media-thickness-and-histopathologic-grade-of-atherosclerosis-in-patients-with-chronic-kidney-disease
#10
Nariman Nezami, Kamyar Ghabili, Behrooz Shokouhi-Gogani, Mohammad Mirchi, Morteza Ghojazadeh, Javid Safa, Afshar Zomorrodi, Abasad Gharadaghi, Mohammad Khalid Mojadidi, Mohammad Kazem Tarzamni, Ghazal Khajir, Sona Ghorashi, Margarita Revzin
BACKGROUND/AIMS: Variability in the grade of atherosclerosis among patients with chronic kidney disease (CKD) could affect the ultrasound measurements of intima media thickness (IMT). We sought to investigate IMTs of carotid (cIMT) and femoral (fIMT) arteries in CKD patients and assess the degree of their correlation with histopathological atherosclerosis. METHODS: Eighty-nine out of 99 enrolled subjects completed this study. The subjects were divided into 3 groups: 34 patients with CKD (Case group), 31 with coronary artery disease undergoing coronary artery bypass graft (CABG, positive control group), and 24 healthy kidney donors (negative control group)...
March 7, 2018: Nephron
https://www.readbyqxmd.com/read/29497612/cardiovascular-imaging-techniques-in-systemic-rheumatic-diseases
#11
REVIEW
Fabiola Atzeni, Marco Corda, Luigi Gianturco, Maurizio Porcu, Piercarlo Sarzi-Puttini, Maurizio Turiel
The risk of cardiovascular (CV) events and mortality is significantly higher in patients with systemic rheumatic diseases than in the general population. Although CV involvement in such patients is highly heterogeneous and may affect various structures of the heart, it can now be diagnosed earlier and promptly treated. Various types of assessments are employed for the evaluation of CV risk such as transthoracic or transesophageal echocardiography, magnetic resonance imaging (MRI), and computed tomography (CT) to investigate valve abnormalities, pericardial disease, and ventricular wall motion defects...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/29462898/do-nonalcoholic-fatty-liver-disease-and-fetuin-a-play-different-roles-in-symptomatic-coronary-artery-disease-and-peripheral-arterial-disease
#12
Fabio Nascimbeni, Dante Romagnoli, Stefano Ballestri, Enrica Baldelli, Simonetta Lugari, Valentina Sirotti, Valentina Giampaoli, Amedeo Lonardo
BACKGROUND AND AIMS: Nonalcoholic fatty liver disease (NAFLD) is strongly associated with both atherosclerotic cardiovascular disease (CVD) and Fetuin-A. However, the association of Fetuin-A with atherosclerosis is more controversial. We hypothesized that the pathogenic interplay of NAFLD, Fetuin-A and atherosclerosis varies based on arterial site. Accordingly, we aimed to assess NAFLD prevalence, Fetuin-A values and their relationship with symptomatic atherosclerosis occurring in different localizations: coronary artery disease (CAD) vs...
February 16, 2018: Diseases (Basel)
https://www.readbyqxmd.com/read/29445076/clinical-utility-of-carotid-ultrasonography-in-the-prediction-of-cardiovascular-events-in-patients-with-diabetes-a-combined-analysis-of-data-obtained-in-five-longitudinal-studies
#13
Naoto Katakami, Tomoya Mita, Masahiko Gosho, Mitsuyoshi Takahara, Yoko Irie, Tetsuyuki Yasuda, Taka-Aki Matsuoka, Takeshi Osonoi, Hirotaka Watada, Iichiro Shimomura
AIM: It remains unclear whether measures used in carotid ultrasonography such as the intima-media thickness (IMT) and ultrasonic tissue characterization of the carotid using the gray-scale median (GSM) can add prognostic information beyond the conventional cardiovascular risk markers in patients with diabetes. METHODS: This study employed a combined analysis of data obtained in five longitudinal studies including a total of 3263 patients with diabetes but without apparent cardiovascular disease (CVD) at baseline...
February 14, 2018: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/29351856/high-density-lipoprotein-with-apolipoprotein-c-iii-is-associated-with-carotid-intima-media-thickness-among-generally-healthy-individuals
#14
Rain Yamamoto, Frank M Sacks, Frank B Hu, Bernard Rosner, Jeremy D Furtado, Sarah A Aroner, Ele Ferrannini, Simona Baldi, Michaela Kozakova, Beverley Balkau, Andrea Natali, Majken K Jensen
BACKGROUND AND AIMS: About 6-7% of high density lipoprotein (HDL) has a protein called apolipoprotein (apo) C-III that regulates lipoprotein metabolism and can provoke an inflammatory response. HDL without apoC-III is inversely associated with coronary heart disease (CHD), whereas HDL with apoC-III is directly associated with CHD. We investigated how the presence of apoC-III affects the association between HDL and early stages of atherosclerosis measured as carotid intima-media thickness (cIMT)...
February 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29279888/prevalence-of-systemic-atherosclerosis-burdens-and-overlapping-stroke-etiologies-and-their-associations-with-long-term-vascular-prognosis-in-stroke-with-intracranial-atherosclerotic-disease
#15
Takao Hoshino, Leila Sissani, Julien Labreuche, Gregory Ducrocq, Philippa C Lavallée, Elena Meseguer, Céline Guidoux, Lucie Cabrejo, Cristina Hobeanu, Fernando Gongora-Rivera, Pierre-Jean Touboul, Philippe Gabriel Steg, Pierre Amarenco
Importance: Patients who have experienced stroke with intracranial atherosclerotic disease (ICAD) may also have concomitant atherosclerosis in different arterial beds and other possible causes for ischemic stroke. However, little is known about the frequency and prognostic effect of such overlapping diseases. Objectives: To describe the prevalence of systemic atherosclerotic burdens and overlapping stroke etiologies and their contributions to long-term prognoses among patients who have experienced stroke with ICAD...
February 1, 2018: JAMA Neurology
https://www.readbyqxmd.com/read/29274406/association-between-non-alcoholic-fatty-liver-disease-and-subclinical-coronary-atherosclerosis-an-observational-cohort-study
#16
Seung Bum Lee, Gyung-Min Park, Jong-Young Lee, Byung Uk Lee, Jae Ho Park, Byung Gyu Kim, Seok Won Jung, In Du Jeong, Sung-Jo Bang, Jung Woo Shin, Neung Hwa Park, Dong Hyun Yang, Joon-Won Kang, Tae-Hwan Lim, Hong-Kyu Kim, Jaewon Choe, Han Chu Lee
BACKGROUND & AIMS: There are limited data on the association between non-alcoholic fatty liver disease (NAFLD) and subclinical coronary atherosclerosis. This study investigated the influence of NAFLD on subclinical coronary atherosclerosis as detected by coronary computed tomography angiography (CCTA) in an asymptomatic population. METHODS: A total of 5,121 consecutive asymptomatic individuals with no prior history of coronary artery disease or significant alcohol intake voluntarily underwent abdominal ultrasonography and CCTA as part of a general health examination...
December 20, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/29046974/stress-echocardiography-in-stable-coronary-artery-disease
#17
REVIEW
Sothinathan Gurunathan, Roxy Senior
PURPOSE OF REVIEW: Stress echocardiography (SE) is a well-established technique for the diagnosis and risk stratification of patients with known or suspected coronary artery disease (CAD). This review article summarizes the status of SE in CAD, including testing protocols, clinical efficacy and current use of newer technologies: myocardial perfusion, strain imaging, three-dimensional echocardiography and adjunctive carotid ultrasonography. RECENT FINDINGS: Recent major findings in SE include the clinical value of myocardial perfusion imaging in multicentre studies, as well as when added to left ventricular (LV) wall motion assessment in clinical service...
October 18, 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/29042949/angina-in-granulomatosis-with-polyangiitis-a-case-report
#18
Huijie Dong, Dayuan Lou, Xiaofei Ji, Peng Qu
Granulomatosis with polyangiitis (GPA) often causes small blood vessel lesions in multiple organs, with less impact on large vessels. We report a case involving not only large blood vessels, but also angina. The computed tomographic angiography of large vessels and vascular ultrasonography of the extremity also suggested great arteries of the body were involved. Further cytoplasmic antineutrophil cytoplasmic antibody tests, pathological examination and dynamic chest computed tomography scan confirmed the diagnosis of GPA...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29027678/evaluation-of-carotid-plaque-neovascularization-in-patients-with-coronary-heart-disease-on-contrast-enhanced-ultrasonography
#19
Chuan Qin, Li Zhang, Xinfang Wang, Yilian Duan, Zhou Ye, Mingxing Xie
OBJECTIVES: To examine the repeatability of quantitative time-intensity curve analysis of neovascularization within carotid plaques with contrast-enhanced ultrasonography (US) and to investigate carotid plaque neovascularization in patients with coronary heart disease using contrast-enhanced US and the correlation between risk factors and acute coronary syndrome (ACS). METHODS: Sixty patients with ACS and 60 with stable coronary artery disease (CAD) underwent conventional carotid and contrast-enhanced US, and plaque enhancement was observed and analyzed quantitatively...
October 13, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28947310/assessments-of-carotid-artery-plaque-burden-in-patients-with-familial-hypercholesterolemia
#20
Hayato Tada, Masa-Aki Kawashiri, Hirofumi Okada, Takuya Nakahashi, Kenji Sakata, Atsushi Nohara, Akihiro Inazu, Hiroshi Mabuchi, Masakazu Yamagishi, Kenshi Hayashi
Although both carotid intima-media thickness (cIMT) and carotid plaque score (cPS) determined by carotid ultrasonography reflect the severity of coronary atherosclerosis, there are few reports on direct comparisons of their clinical utilities in patients with familial hypercholesterolemia (FH). We aimed (1) to compare the clinical utilities of these measurements and (2) to estimate the onset and progression of carotid atherosclerosis in patients with FH. We examined 225 patients with FH (126 males; mean age, 51 ± 18 years) who underwent carotid ultrasonography...
December 1, 2017: American Journal of Cardiology
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