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https://www.readbyqxmd.com/read/29152676/coraliitalea-coralii-gen-nov-sp-nov-a-marine-bacterium-of-the-family-flavobacteriaceae-isolated-from-the-hard-coral-galaxea-fascicularis
#1
Jaewoo Yoon, Mina Yasumoto-Hirose, Hiroaki Kasai
A polyphasic taxonomic study was performed on a novel strain designated as 04OKA-3-121(T), which was isolated from the hard coral Galaxea fascicularis L. collected at Akajima, Okinawa, Japan. These bacterial cells were observed to be pale-yellow, Gram-stain-negative, strictly aerobic, chemoheterotrophic, non-spore forming, non-motile, and rod-shaped. Phylogenetic analysis based on the 16S rRNA gene sequence revealed that the novel marine isolate is affiliated with the family Flavobacteriaceae of the phylum Bacteroidetes and that it shared the highest (93...
November 20, 2017: Current Microbiology
https://www.readbyqxmd.com/read/29149314/how-the-introduction-of-a-human-resources-information-system-helped-the-democratic-republic-of-congo-to-mobilise-domestic-resources-for-an-improved-health-workforce
#2
Jean-Robert Likofata Esanga, Claire Viadro, Leah McManus, Jennifer Wesson, Nicaise Matoko, Epiphane Ngumbu, Kate E Gilroy, Daren Trudeau
The Democratic Republic of Congo has flagged health workforce management and compensation as issues requiring attention, including the problem of ghost workers (individuals on payroll who do not exist and/or show up at work). Recognising the need for reliable health workforce information, the government has worked to implement iHRIS, an open source human resources information system that facilitates health workforce management. In Kasaï Central and Kasaï Provinces, health workers brought relevant documentation to data collection points, where trained teams interviewed them and entered contact information, identification, photo, current job, and employment and education history into iHRIS on laptops...
November 1, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/29146707/outcomes-after-allogeneic-hematopoietic-stem-cell-transplantation-in-patients-with-acute-myeloid-leukemia-harboring-t-7-11-p15-p15
#3
Kaito Harada, Noriko Doki, Jun Aoki, Jinichi Mori, Shinichiro Machida, Masayoshi Masuko, Naoyuki Uchida, Yuho Najima, Takahiro Fukuda, Heiwa Kanamori, Hiroyasu Ogawa, Shuichi Ota, Kazuei Ogawa, Satoshi Takahashi, Masanobu Kasai, Akio Maeda, Koji Nagafuji, Toshiro Kawakita, Tatsuo Ichinohe, Yoshiko Atsuta
No abstract text is available yet for this article.
November 16, 2017: Haematologica
https://www.readbyqxmd.com/read/29145877/trajectory-of-instantaneous-axis-of-rotation-in-fixed-lumbar-spine-with-instrumentation
#4
Masataka Inoue, Tetsutaro Mizuno, Toshihiko Sakakibara, Takaya Kato, Takamasa Yoshikawa, Tadashi Inaba, Yuichi Kasai
BACKGROUND: Several studies showed instantaneous axis of rotation (IAR) in the intact spine. However, there has been no report on the trajectory of the IAR of a damaged spine or that of a fixed spine with instrumentation. It is the aim of this study to investigate the trajectory of the IAR of the lumbar spine using the vertebra of deer. METHODS: Functional spinal units (L5-6) from five deer were evaluated with six-axis material testing machine. As specimen models, we prepared a normal model, a damaged model, and a pedicle screw (PS) model...
November 16, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29128938/liver-fibrosis-noninvasive-assessment-using-supersonic-shear-imaging-and-fib4-index-in-patients-with-non-alcoholic-fatty-liver-disease
#5
Hirohito Takeuchi, Katsutoshi Sugimoto, Hisashi Oshiro, Kunio Iwatsuka, Shin Kono, Yu Yoshimasu, Yoshitaka Kasai, Yoshihiro Furuichi, Kentaro Sakamaki, Takao Itoi
PURPOSE: Shear wave elastography (SWE) has been validated in chronic hepatitis C and B; however, limited data are available in non-alcoholic fatty liver disease (NAFLD). This study aimed to evaluate the accuracy of SWE and FIB4 index for the diagnosis of fibrosis in a cohort of consecutive patients with biopsy-proven NAFLD, and to evaluate the effects of other histologic parameters on SWE measurement. METHODS: Written informed consent was obtained from all patients, and this study was approved by our internal review board and ethics committee...
November 11, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29124933/total-synthesis-of-polycavernosides-a-and-b-two-lethal-toxins-from-red-alga
#6
Kotaro Iwasaki, Satori Sasaki, Yusuke Kasai, Yuki Kawashima, Shohei Sasaki, Takanori Ito, Mari Yotsu-Yamashita, Makoto Sasaki
Polycavernosides A and B are glycosidic macrolide natural products isolated as the toxins causing fatal human poisoning by the edible red alga Gracilaria edulis (Polycavernosa tsudai). Total synthesis of polycavernosides A and B has been achieved via a convergent approach. The synthesis of the macrolactone core structure is highlighted by the catalytic asymmetric syntheses of the two key fragments using hetero-Diels-Alder reaction and Kiyooka aldol reaction as the key steps, their union through Suzuki-Miyaura coupling, and Keck macrolactonization...
November 10, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29118687/renoportal-anastomosis-in-left-lateral-lobe-living-donor-liver-transplantation-a-pediatric-case
#7
Hiroyuki Ogasawara, Chikashi Nakanishi, Shigehito Miyagi, Kazuaki Tokodai, Yasuyuki Hara, Wataru Nakanishi, Koji Miyazawa, Kenji Shimizu, Hiroyuki Kumata, Hitoshi Goto, Masafumi Goto, Michiaki Unno, Takashi Kamei
In adult liver transplantation, renoportal anastomosis (RPA) has been introduced as a useful technique for patients with grade 4 portal vein thrombosis and a splenorenal shunt. Here, we report a pediatric case in which RPA allowed a left lateral lobe living donor liver transplantation (LDLT) despite portal vein thrombosis and a large splenorenal shunt. At 36 days old, the patient underwent a Kasai operation for biliary atresia. At 17 months old, she underwent LDLT because of repetitive cholangitis. Pretransplant examinations revealed a large splenorenal shunt and portal vein thrombosis...
September 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29116599/the-class-a-gpcr-dopamine-d2-receptor-forms-transient-dimers-stabilized-by-agonists-detection-by-single-molecule-tracking
#8
Rinshi S Kasai, Shuichi V Ito, Ryo M Awane, Takahiro K Fujiwara, Akihiro Kusumi
Whether class-A G-protein coupled receptors (GPCRs) exist and work as monomers or dimers has drawn extensive attention. A class-A GPCR dopamine D2 receptor (D2R) is involved in many physiological and pathological processes and diseases, indicating its critical role in proper functioning of neuronal circuits. In particular, D2R homodimers might play key roles in schizophrenia development and amphetamine-induced psychosis. Here, using single-molecule imaging, we directly tracked single D2R molecules in the plasma membrane at a physiological temperature of 37 °C, and unequivocally determined that D2R forms transient dimers with a lifetime of 68 ms in its resting state...
November 7, 2017: Cell Biochemistry and Biophysics
https://www.readbyqxmd.com/read/29115928/the-japanese-version-of-the-questionnaire-about-the-process-of-recovery-development-and-validity-and-reliability-testing
#9
Akiko Kanehara, Risa Kotake, Yuki Miyamoto, Yousuke Kumakura, Kentaro Morita, Tomoko Ishiura, Kimiko Shimizu, Yumiko Fujieda, Shuntaro Ando, Shinsuke Kondo, Kiyoto Kasai
BACKGROUND: Personal recovery is increasingly recognised as an important outcome measure in mental health services. This study aimed to develop a Japanese version of the Questionnaire about the Process of Recovery (QPR-J) and test its validity and reliability. METHODS: The study comprised two stages that employed the cross-sectional and prospective cohort designs, respectively. We translated the questionnaire using a standard translation/back-translation method...
November 7, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29110825/long-term-outlook-in-biliary-atresia
#10
Arun Kelay, Mark Davenport
The oldest survivors from the Kasai portoenterostomy originate in Sendai, Japan and are approaching their 60th birthday. These represent the tip of an expanding cohort of adults born with this previously fatal condition. Increasingly transition to adult-biased hepatologists and physicians will be the expectation of many with this condition. However unlike their usual patients with alcohol, drugs, virally mediated liver disease these are different with different expectations of health and quality of life. Cure is not on the cards for most of these and they survive still with impaired bile flow and increased liver fibrosis and cirrhosis with the threat of cholangitis and portal hypertension still apparent...
October 2017: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/29089158/cerebellar-ataxia-with-neuropathy-and-vestibular-areflexia-syndrome-canvas
#11
Masakatsu Taki, Takashi Nakamura, Hiraku Matsuura, Tatsuhisa Hasegawa, Hirofumi Sakaguchi, Kanako Morita, Ryotaro Ishii, Ikuko Mizuta, Takashi Kasai, Toshiki Mizuno, Shigeru Hirano
Cerebellar ataxia with neuropathy and bilateral vestibular areflexia syndrome (CANVAS) is a novel ataxic disorder consisting of the triad of cerebellar impairment, bilateral vestibular hypofunction, and a somatosensory deficit. We report the first Japanese case of CANVAS. The patient is a 68-year-old Japanese male. He was referred to our university for further evaluation of progressive gait disturbance and ataxia. He exhibited horizontal gaze-evoked nystagmus and sensory deficit. Nerve conduction studies showed sensory neuronopathy...
October 28, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29082054/expectant-management-leading-to-successful-vaginal-delivery-following-intrauterine-fetal-death-in-a-woman-with-an-incarcerated-uterus
#12
Masafumi Yamamoto, Mio Takami, Ryosuke Shindo, Michi Kasai, Shigeru Aoki
Expectant management leads to successful vaginal delivery following intrauterine fetal death in a woman with an incarcerated uterus. Management of intrauterine fetal death in the second or third trimester of pregnancy in women with an incarcerated uterus is challenging. We report a case of successful vaginal delivery following intrauterine fetal death by expectant management in a woman with an incarcerated uterus. In cases of intrauterine fetal death in women with an incarcerated uterus, vaginal delivery may be possible if the incarceration is successfully reduced...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29081513/localization-of-the-primary-sites-of-involvement-in-the-spinal-sensory-and-motor-pathways-for-multilevel-mri-abnormalities-in-degenerative-cervical-myelopathy
#13
Nobuaki Tadokoro, Toshikazu Tani, Kazunobu Kida, Katsuhito Kiyasu, Yusuke Kasai, Masashi Kumon, Ryuichi Takemasa, Masahiko Ikeuchi
STUDY DESIGN: Exploratory clinical study. OBJECTIVES: To localize the sites of conduction block in the spinal sensory and motor pathways for minimizing the level of surgical intervention despite MRI evidence of compression at several levels in degenerative cervical myelopathy (DCM). SETTING: Kochi Medical School Hospital, Japan. METHODS: We analyzed 83 DCM patients (69 ± 12 years) who underwent serial intervertebral recording of both ascending (A-SCEPs) and descending spinal cord-evoked potentials (D-SCEPs) after epidural and transcranial stimulation, respectively, during surgery before decompression procedures...
October 30, 2017: Spinal Cord
https://www.readbyqxmd.com/read/29073937/tumoral-calcinosis-in-the-cervical-spine-a-case-report-and-review-of-the-literature
#14
Rui Guo, Tatsuya Kurata, Tetsushi Kondo, Takao Imanishi, Tetsutaro Mizuno, Toshihiko Sakakibara, Yuichi Kasai
BACKGROUND: Tumoral calcinosis is rarely located in spine. A 55-year-old Japanese woman with cervical tumoral calcinosis is presented, along with a review of the literature relating to tumoral calcinosis in the spine. We discussed the etiology, diagnosis, and management of this condition. CASE PRESENTATION: We report a case of a patient with cervical tumoral calcinosis with end-stage renal disease. A computed tomography scan showed a lobulated, calcified mass around the right facet joint at the fourth-fifth cervical spine and calcifications were also observed in the right intervertebral foramens at fourth-fifth cervical spine and fifth-sixth cervical spine levels and the anterior wall of the spinal canal...
October 27, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29070850/tuning-methane-decomposition-on-stepped-ni-surface-the-role-of-subsurface-atoms-in-catalyst-design
#15
Ryan Lacdao Arevalo, Susan Meñez Aspera, Mary Clare Sison Escaño, Hiroshi Nakanishi, Hideaki Kasai
The decomposition of methane (CH4) is a catalytically important reaction in the production of syngas that is used to make a wide spectrum of hydrocarbons and alcohols, and a principal carbon deposition pathway in methane reforming. Literatures suggest that stepped Ni surface is uniquely selective toward methane decomposition to atomic C, contrary to other catalysts that favor the CH fragment. In this paper, we used dispersion-corrected density functional theory-based first principles calculations to identify the electronic factors that govern this interesting property of stepped Ni surface...
October 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29066822/dysregulated-gene-expressions-of-mex3d-fos-and-bcl2-in-human-induced-neuronal-in-cells-from-nf1-patients-a-pilot-study
#16
Noriaki Sagata, Takahiro A Kato, Shin-Ichi Kano, Masahiro Ohgidani, Norihiro Shimokawa, Mina Sato-Kasai, Kohei Hayakawa, Nobuki Kuwano, Ashley M Wilson, Koko Ishizuka, Shiori Kato, Takeshi Nakahara, Makiko Nakahara-Kido, Daiki Setoyama, Yasunari Sakai, Shouichi Ohga, Masutaka Furue, Akira Sawa, Shigenobu Kanba
Direct conversion technique to produce induced-neuronal (iN) cells from human fibroblasts within 2 weeks is expected to discover unknown neuronal phenotypes of neuropsychiatric disorders. Here, we present unique gene expression profiles in iN cells from patients with neurofibromatosis type 1 (NF1), a single-gene multifaceted disorder with comparatively high co-occurrence of autism spectrum disorder (ASD). Microarray-based transcriptomic analysis on iN cells from male healthy controls and male NF1 patients (NF1-iN cells) revealed that 149 genes expressions were significantly different (110 upregulated and 39 downregulated)...
October 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29065956/distinct-patterns-of-hyperpnea-during-cheyne-stokes-respiration-implication-for-cardiac-function-in-patients-with-heart-failure
#17
Elisa Perger, Toru Inami, Owen D Lyons, Hisham Alshaer, Stephanie Smith, John S Floras, Alexander G Logan, Michael Arzt, Joaquin Duran Cantolla, Diego Delgado, Michael Fitzpatrick, John Fleetham, Takatoshi Kasai, R John Kimoff, Richard S T Leung, Geraldo Lorenzi Filho, Pierre Mayer, Lisa Mielniczuk, Debra L Morrison, Gianfranco Parati, Sairam Parthasarathy, Stefania Redolfi, Clodagh M Ryan, Frederic Series, George A Tomlinson, Anna Woo, T Douglas Bradley
STUDY OBJECTIVES: In heart failure (HF), we observed two patterns of hyperpnea during Cheyne-Stokes respiration with central sleep apnea (CSR-CSA): a positive pattern where end-expiratory lung volume remains at or above functional residual capacity, and a negative pattern where it falls below functional residual capacity. We hypothesized the negative pattern is associated with worse HF. METHODS: Patients with HF underwent polysomnography. During CSR-CSA, hyperpnea, apnea-hyperpnea cycle, and lung to finger circulation times (LFCT) were measured...
October 18, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29064635/voltage-sensitive-sodium-channel-mutations-s989p-v1016g-in-aedes-aegypti-confer-variable-resistance-to-pyrethroids-ddt-and-oxadiazines
#18
Leticia B Smith, Shinji Kasai, Jeffrey G Scott
BACKGROUND: Aedes aegypti is a vector of several important human pathogens. Especially during disease outbreaks, control efforts rely primarily on pyrethroid insecticides for adult mosquito control. A. aegypti has developed resistance nearly everywhere it occurs and insecticides are used. An important mechanism of resistance is due to mutations in the voltage-sensitive sodium channel (Vssc) gene. Two mutations in particular, S989P+V1016G, commonly occur together in parts of Asia. RESULTS: We have created a strain (IsoKDR) that contains the Vssc mutations S989P+V1016G as the only mechanism of pyrethroid resistance within the genetic background of Rockefeller (ROCK), a susceptible lab strain...
October 24, 2017: Pest Management Science
https://www.readbyqxmd.com/read/29063249/early-us-findings-of-biliary-atresia-in-infants-younger-than-30-days
#19
Sook Min Hwang, Tae Yeon Jeon, So-Young Yoo, Yon Ho Choe, Suk-Koo Lee, Ji Hye Kim
PURPOSE: To investigate and compare ultrasound (US) findings for the diagnosis of biliary atresia (BA) in infants younger than 30 days with those of infants older than 30 days. MATERIALS AND METHODS: From 2000 to 2015, we reviewed hepatobiliary US images in 12 BA infants younger than 30 days (younger BA group) and 62 BA infants older than 30 days (older BA group) before Kasai procedure. Eight (67%) of younger BA group underwent follow-up US examinations before Kasai procedure...
October 23, 2017: European Radiology
https://www.readbyqxmd.com/read/29056230/correlation-between-gamma-glutamyl-transpeptidase-activity-and-outcomes-after-kasai-portoenterostomy-for-biliary-atresia
#20
Kyong Ihn, In Geol Ho, Eun Young Chang, Seok Joo Han
BACKGROUND/PURPOSE: The role of serum gamma-glutamyl transpeptidase (GGT) levels in predicting clinical outcomes after Kasai portoenterostomy (KPE) is unknown. This study analyzed whether postoperative GGT along with the aspartate aminotransferase-to-platelet ratio index (APRi) predicted prognosis of biliary atresia (BA). METHODS: Data were retrospectively reviewed for 169 BA patients categorized into jaundice-free (JF) (total bilirubin <2.0 mg/dL ≤6 months post-KPE) and persistent jaundice (PJ) groups (total bilirubin ≥2...
October 6, 2017: Journal of Pediatric Surgery
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