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Sujin Bahk, GyeongHyeon Doh, Ki Yong Hong, SooA Lim, SuRak Eo
Reconstruction of soft tissue defects in the foot remains a challenge due to its specialized tissue for weightbearing and ambulation. Considering the principle of replacing "like with like," adjacent soft tissues would be a best option for a donor site. Although several kinds of reverse-flow island flaps for the lower leg have been well described, intrinsic foot reverse flow flaps have been rarely reported. We describe 3 kinds of reverse-flow intrinsic fasciocutaneous flaps (RIFFs) for foot reconstruction. From September 2012 to August 2015, a retrospective study was done on case notes of all patients who had a RIFF for coverage of soft tissue defects within the foot following trauma or tumor ablation...
November 1, 2017: International Journal of Lower Extremity Wounds
Ki Yong Hong, Sangjun Yim, Hyun Jung Kim, Ung Sik Jin, SooA Lim, SuRak Eo, Hak Chang, Kyung Won Minn
BACKGROUND: Cell-assisted lipotransfer (CAL) is a process in which fat grafting is supplemented with autologous adipose-derived stromal cells (ASCs). Since the efficacy of the technique was demonstrated, studies have focused on the mechanism by which CAL enhances the rate of graft survival. However, the microenvironmental changes in donor and recipient tissue associated with CAL remain unclear. METHODS: We introduced an animal model of CAL using two different transgenic reporter mice...
October 12, 2017: Plastic and Reconstructive Surgery
Jungho Yeo, Yuntae Kim, Sooa Kim, Kiyoung Oh, Hyungdong Kang
OBJECTIVE: To obtain reference values, to suggest optimal recording and stimulation site for radial motor nerve conduction study (RmNCS), and to analyze the correlation among RmNCS parameters, demographics and ultrasonography (US) findings. METHODS: A total of 55 volunteers participated in this study. We hypothesized that 'lateral edge of spiral groove (A)' was the optimal stimulation site, and the 'largest cross-sectional area (CSA) of extensor indicis proprius (EIP) muscle (B)' was the optimal recording site...
April 2017: Annals of Rehabilitation Medicine
Yeon Ji Kim, Woo Chul Chung, Sooa Choi, Yun Duk Jung, Jaejun Lee, Seung Yun Chae, Kyong Hwa Jun, Hyung Min Chin
Background/Aims: Peritoneal micrometastasis is known to play an important role in the recurrence of gastric cancer. However, its effects remain equivocal. Herein, we examine the messenger RNA (mRNA) as tumor markers, carcinoembryonic antigen (CEA), and cytokeratin 20 (CK20), in peritoneal washing fluid. Moreover, we evaluate whether these results could predict the recurrence of gastric cancer following curative resection. Methods: We prospectively enrolled 132 patients with gastric cancers, who had received an operation, between January 2010 and January 2013...
April 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
Yeon Ji Kim, Dae Bum Kim, Woo Chul Chung, Ji Min Lee, Gun Jung Youn, Yun Duk Jung, Sooa Choi, Jung Hwan Oh
OBJECTIVE: Acute pancreatitis (AP) ranges from a mild and self-limiting disease to a fulminant illness with significant morbidity and mortality. Severe acute pancreatitis (SAP) is defined as persistent organ failure lasting for 48 h. We aimed to determine the factors that predict survival and mortality in patients with SAP. METHODS: We reviewed a consecutive series of patients who were admitted with acute pancreatitis between January 2003 and January 2013. A total of 1213 cases involving 660 patients were evaluated, and 68 cases with SAP were selected for the study...
August 2017: Scandinavian Journal of Gastroenterology
Ji Min Lee, Woo Chul Chung, Hea Jung Sung, Yeon-Ji Kim, Gun Jung Youn, Yun Duk Jung, Sooa Choi, Eun Jung Jeon
OBJECTIVE: Recurrent attacks after acute gallstone pancreatitis (GSP) are substantial problems, together with associated morbidity and mortality. The recommended therapies for recurrent attacks are cholecystectomy and endoscopic sphincterotomy (EST). This study aimed to evaluate the long-term results of cholecystectomy and EST after clinical improvement of GSP. METHODS: A consecutive series of patients who were admitted with GSP from January 2003 to December 2014 were analyzed...
January 2017: Journal of Digestive Diseases
Y P Li, K X Zhao, H Z Ma
OBJECTIVE: To investigate the effect and safety of the graduated "hang-back" recession of superior oblique (SO) in treatment of A-pattern strabismus with superior oblique overaction (SOOA). METHODS: Retrospective study. The clinical data of 15 cases (28 eyes), who underwent graduated "hang-back" recession of SO depending on the scales of SOOA, were collected and analyzed. The principle we carried on was hang-back recession 8-10mm for SOOA+4, 6 to 8 mm for SOOA+3, 5 to 6 mm for SOOA+2 and 4 mm for SOOA+1...
August 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Jinil Kim, Yuntae Kim, Sooa Kim, Kiyoung Oh
Hirayama disease is a slowly progressing benign motor neuron disease that affects the distal upper limb. A 29-year-old man visited the hospital with a 1-year history of weakened left proximal upper limb. He was diagnosed with Hirayama disease 9 years ago, while there was no further progression of the muscle weakness afterward. Atrophy and weakness was detected in proximal upper limb muscles. Magnetic resonance imaging and somatosensory evoked potentials were normal. Needle electromyography showed abnormal findings in proximal upper limb muscles...
October 2016: Journal of Korean Medical Science
Mi-Hyang Jung, Dong Il Shin, Ik Jun Choi, Suk Min Seo, Sooa Choi, Mahn Won Park, Pum-Joon Kim, Sang Hong Baek, Ki-Bae Seung
PURPOSE: The association between the red cell distribution width (RDW) and vasospastic angina (VSA) has not been elucidated. We investigated the association of the RDW with the incidence and angiographic subtypes of VSA in Korean patients. MATERIALS AND METHODS: A total of 460 patients who underwent intracoronary ergonovine provocation tests were consecutively enrolled and classified into two groups: the VSA group (n=147, 32.0%) and non-VSA group (n=313, 68.0%)...
May 2016: Yonsei Medical Journal
Yueping Li, Huizhi Ma, Kanxing Zhao
PURPOSE: To investigate the efficacy and safety of bilateral hang-back recession of superior oblique (SO) muscles in the treatment of A-pattern strabismus with superior oblique overaction (SOOA). METHODS: Thirty-one (31) patients (62 eyes) with A-pattern horizontal deviation and SOOA underwent hang-back recession of SO and retrospective analysis of the surgical amount of hang-back recession of SO, preoperative and postoperative A-pattern, ocular motility, and corrected objective torsion...
2016: Strabismus
SooA Lim, Esteban Marcellin, Shana Jacob, Lars K Nielsen
Little is known about the role of global phosphorylation events in the control of prokaryote metabolism. By performing a detailed analysis of all protein phosphorylation events previously reported in Escherichia coli, dynamic changes in protein phosphorylation were elucidated under three different culture conditions. Using scheduled reaction monitoring, the phosphorylation ratios of 82 peptides corresponding to 71 proteins were quantified to establish whether serine (S), threonine (T) and tyrosine (Y) phosphorylation events displayed a dynamic profile under changing culture conditions...
August 3, 2015: Journal of Proteomics
Jitendra Jethani, Kuntal Shah, Sonal Amin
INTRODUCTION: Superior oblique split lengthening (SOSL) is done for weakening of superior oblique. It corrects the superior oblique overaction (SOOA) and A pattern. Its effect on the torsion of the eye is not known. We present our data on the effect of this particular procedure on torsion. MATERIALS AND METHODS: We did a study of 16 patients (32 eyes) who underwent bilateral SOSL and compared the disc foveal angle (DFA) preoperatively and postoperatively. The split lengthening was done from 4 mm to 7 mm depending upon the overaction of superior oblique...
March 2015: Indian Journal of Ophthalmology
Yoo A Choi, Sang Hoon Yoo, Youn Mi Song, Se Young Kim, Yunju Nam, Sooa Choi, Bong Han Kong, Hye Eun Yoon, Yu Ah Hong, Yoon Kyung Chang, Chul Woo Yang, Suk Young Kim, Hyeon Seok Hwang
PURPOSE: The immunochemical fecal occult blood test (iFOBT) is a useful method to screen for lower gastrointestinal (GI) bleeding-related lesions. However, few studies have investigated the diagnostic utility of iFOBT in chronic kidney disease (CKD). METHODS: We included 691 patients with nondialysis-dependent CKD stages 2-5 or those receiving dialysis. Bleeding-related lower GI lesions were identified by colonoscopy, and the diagnostic utility of iFOBT was evaluated...
July 2015: International Journal of Colorectal Disease
Hea Jung Sung, Woo Chul Chung, Ji Woong Roh, Sooa Choi, Yoon Goo Kang, So Lim Hong, Kang Won Cho
BACKGROUND/AIMS: Globus is a persistent or intermittent non-painful sensation of a lump or foreign body in the throat and a commonly encountered clinical condition. We aim to evaluate the prevalence of gastroesophageal reflux disease (GERD) and to determine the parameters for predicting the response to treatment with proton pump inhibitor (PPI) using wireless pH monitoring in patients with globus sense. METHODS: We retrospectively reviewed the medical records of 37 patients with atypical GERD symptoms...
February 2015: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
Yalun Arifin, Colin Archer, SooA Lim, Lake-Ee Quek, Haryadi Sugiarto, Esteban Marcellin, Claudia E Vickers, Jens O Krömer, Lars K Nielsen
Sugarcane is the most efficient large-scale crop capable of supplying sufficient carbon substrate, in the form of sucrose, needed during fermentative feedstock production. However, sucrose metabolism in Escherichia coli is not well understood because the two most common strains, E. coli K-12 and B, do not grow on sucrose. Here, using a sucrose utilizing strain, E. coli W, we undertake an in-depth comparison of sucrose and glucose metabolism including growth kinetics, metabolite profiling, microarray-based transcriptome analysis, labelling-based proteomic analysis and (13)C-fluxomics...
November 2014: Applied Microbiology and Biotechnology
Cuauhtemoc Licona-Cassani, Sooa Lim, Esteban Marcellin, Lars K Nielsen
Actinomycetes undergo a dramatic reorganization of metabolic and cellular machinery during a brief period of growth arrest ("metabolic switch") preceding mycelia differentiation and the onset of secondary metabolite biosynthesis. This study explores the role of phosphorylation in coordinating the metabolic switch in the industrial actinomycete Saccharopolyspora erythraea. A total of 109 phosphopeptides from 88 proteins were detected across a 150-h fermentation using open-profile two-dimensional LC-MS proteomics and TiO(2) enrichment...
May 2014: Molecular & Cellular Proteomics: MCP
May Hijazi, Jessica Durand, Carole Pichereaux, Frédéric Pont, Elisabeth Jamet, Cécile Albenne
Proteins are important actors in plant cell walls because they contribute to their architecture and their dynamics. Among them, hydroxyproline (Hyp)-rich glycoproteins constitute a complex family of O-glycoproteins with various structures and functions. In this study, we characterized an atypical Hyp-rich glycoprotein, AGP31 (arabinogalactan protein 31), which displays a multidomain organization unique in Arabidopsis thaliana, consisting of a short arabinogalactan protein (AGP) motif, a His stretch, a Pro-rich domain, and a C-terminal PAC (PRP-AGP containing Cys) domain...
March 16, 2012: Journal of Biological Chemistry
Sang-Yeon Suh, Youn Seon Choi, Jae Yong Shim, Young Sung Kim, Chang Hwan Yeom, Daeyoung Kim, Shin Ae Park, Sooa Kim, Ji Yeon Seo, Su Hyun Kim, Daegyeun Kim, Sung-Eun Choi, Hong-Yup Ahn
GOALS OF WORK: The goal of this study was to develop a new, objective prognostic score (OPS) for terminally ill cancer patients based on an integrated model that includes novel objective prognostic factors. MATERIALS AND METHODS: A multicenter study of 209 terminally ill cancer patients from six training hospitals in Korea were prospectively followed until death. The Cox proportional hazard model was used to adjust for the influence of clinical and laboratory variables on survival time...
February 2010: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Sang Woo Park, Hwang Gyun Kim, Hwan Heo, Yeoung Geol Park
Axenfeld-Rieger syndrome (ARS) is associated with ocular and systemic anomalies. PITX2 is known to be a major controlling gene in the pathogenesis of ARS and is associated with differentiation in both the neural crest and mesoderm during eye development. A 4-year-old girl with bilateral ARS had 20 prism diopters (PD) of exotropia with 30PD of A- pattern deviation, more than 20PD of dissociated vertical deviation (DVD), and severe superior oblique overaction (SOOA). During surgery we observed that the SO inserted more posteriorly than normal...
March 2009: Korean Journal of Ophthalmology: KJO
Yonina Ron, Moshe Snir, Ruth Axer-Seigel, Ronit Friling
PURPOSE: Few studies have investigated combined surgeries for horizontal deviation and A pattern caused by superior oblique overaction (SOOA). This study presents our experience with combined surgery and examines the effect of the type of strabismus and prior surgery on outcome. METHODS: The medical records of patients who underwent combined surgery for horizontal deviation occurring with A-pattern misalignment from 2000 through 2004 were reviewed. The procedure consisted of horizontal extraocular muscle recession or resection with superior oblique Z-tenotomy...
February 2009: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
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