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https://www.readbyqxmd.com/read/29774980/edwards-sapien-xt%C3%A2-pulmonic-valve-compression-after-resuscitation-and-successful-redilatation
#1
Anja Lehner, Marinos Kantzis, Nikolaus A Haas
Despite the increasing use of percutaenous valves, little is known about valve performance after external chest compression. We report a case of a compressed pulmonary Edwards Sapien® XT valve after resuscitation. With the patient on ECMO, successful redilatation was performed with unimpaired postprocedural valve function. We aim to increase the awareness for valve distortion after external chest compression with increasing numbers of transcatheter valvulations. We suggest that immediate re-evaluation of the implanted device via biplane fluoroscopy is mandatory after resuscitation in such cases...
May 18, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29771965/evaluation-of-commercial-dna-and-rna-extraction-methods-for-high-throughput-sequencing-of-ffpe-samples
#2
Stine H Kresse, Heidi M Namløs, Susanne Lorenz, Jeanne-Marie Berner, Ola Myklebost, Bodil Bjerkehagen, Leonardo A Meza-Zepeda
Nucleic acid material of adequate quality is crucial for successful high-throughput sequencing (HTS) analysis. DNA and RNA isolated from archival FFPE material are frequently degraded and not readily amplifiable due to chemical damage introduced during fixation. To identify optimal nucleic acid extraction kits, DNA and RNA quantity, quality and performance in HTS applications were evaluated. DNA and RNA were isolated from five sarcoma archival FFPE blocks, using eight extraction protocols from seven kits from three different commercial vendors...
2018: PloS One
https://www.readbyqxmd.com/read/29767358/sureselect-xt-rna-direct-a-technique-for-expression-analysis-through-sequencing-of-target-enriched-ffpe-total-rna
#3
Jennifer Carter Jones, Alex P Siebold, Carolina Becker Livi, Anne Bergstrom Lucas
Gene expression profiling of samples from biobanks requires a method that can be used with intact as well as partially degraded RNA. High throughput applications can benefit from reducing the number of processing steps including eliminating the poly(A) selection and ribosomal depletion steps. When performing targeted capture, we have found that we can eliminate the upfront poly(A) selection/ribosomal depletion steps that cause bias in standard mRNA-Seq workflows. This target enrichment solution allows for whole transcriptome or customized content to characterize differential gene expression patterns (especially for mid/low level transcripts)...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29760930/prevalence-of-thrombocytopenia-before-and-after-initiation-of-haart-among-hiv-infected-patients-at-black-lion-specialized-hospital-addis-ababa-ethiopia-a-cross-sectional-study
#4
Gashaw Garedew Woldeamanuel, Diresibachew Haile Wondimu
Background: Hematological abnormalities are common in HIV positive patients. Of these, thrombocytopenia is a known complication which has been associated with a variety of bleeding disorders. However, its magnitude and related factors have not been well-characterized in the era of highly active antiretroviral therapy (HAART) in Ethiopia. Therefore, this study aimed to assess the prevalence of thrombocytopenia before and after initiation of HAART among HIV positive patients attending Black Lion Specialized Hospital, Addis Ababa, Ethiopia...
2018: BMC Hematology
https://www.readbyqxmd.com/read/29752673/lead-exposure-is-associated-with-risk-of-impaired-coagulation-in-preschool-children-from-an-e-waste-recycling-area
#5
Zhijun Zeng, Xia Huo, Yu Zhang, Zhehong Xiao, Yuling Zhang, Xijin Xu
Environmental lead exposure leads to various deleterious effects on multiple organs and systems, including the hematopoietic system. To explore the effects of lead exposure on platelet indices in preschool children from an informal, lead-contaminated electronic waste (e-waste) recycling area, we collected venous blood samples from 466 preschool children (331 from an e-waste area (Guiyu) and 135 from a non-e-waste area (Haojiang)). Child blood lead levels (BLLs) were determined by graphite furnace atomic absorption spectrophotometry, while platelet indices were quantified using a Sysmex XT-1800i hematology analyzer...
May 12, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29732327/microbiological-profile-of-chicken-carcasses-a-comparative-analysis-using-shotgun-metagenomic-sequencing
#6
Alessandra De Cesare, Federica Palma, Alex Lucchi, Frederique Pasquali, Gerardo Manfreda
In the last few years metagenomic and 16S rRNA sequencing have completly changed the microbiological investigations of food products. In this preliminary study, the microbiological profile of chicken carcasses collected from animals fed with different diets were tested by using shotgun metagenomic sequencing. A total of 15 carcasses have been collected at the slaughetrhouse at the end of the refrigeration tunnel from chickens reared for 35 days and fed with a control diet (n=5), a diet supplemented with 1500 FTU/kg of commercial phytase (n=5) and a diet supplemented with 1500 FTU/kg of commercial phytase and 3g/kg of inositol (n=5)...
March 31, 2018: Italian Journal of Food Safety
https://www.readbyqxmd.com/read/29732302/antibacterial-and-remineralization-effects-of-orthodontic-bonding-agents-containing-bioactive-glass
#7
You-Min Kim, Dong-Hyun Kim, Chang Weon Song, Seog-Young Yoon, Se-Yeon Kim, Hee Sam Na, Jin Chung, Yong-Il Kim, Yong Hoon Kwon
Objective: The aim of this study was to evaluate the mechanical and biological properties of orthodontic bonding agents containing silver- or zinc-doped bioactive glass (BAG) and determine the antibacterial and remineralization effects of these agents. Methods: BAG was synthesized using the alkali-mediated solgel method. Orthodontic bonding agents containing BAG were prepared by mixing BAG with flowable resin. Transbond™ XT (TXT) and Charmfil™ Flow (CF) were used as controls...
May 2018: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/29721226/enamel-evaluation-by-scanning-electron-microscopy-after-debonding-brackets-and-removal-of-adhesive-remnants
#8
Dikson Claudino, Milton-Carlos Kuga, Lauriê Belizário, Jefferson-Ricardo Pereira
Background: The bonding of accessories in the dental crown during the orthodontic treatment creates microporosities, thus promoting micromechanical retention of the adhesive to the enamel structure. After debonding brackets, at the end of the active orthodontic treatment, a certain amount of adhesive remnants must be mechanically removed from the enamel. The objective of this study was to compare, by means of scanning electron microscopy, three different methods to remove the adhesive remnants after orthodontic bracket removal...
March 2018: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29706182/prognostic-impact-of-calcium-score-after-transcatheter-aortic-valve-implantation-performed-with-new-generation-prosthesis
#9
Mariama Akodad, Benoit Lattuca, Audrey Agullo, Jean-Christophe Macia, Thomas Gandet, Grégory Marin, Anaïs Iemmi, Hélène Vernhet, Laurent Schmutz, Nicolas Nagot, Bernard Albat, Guillaume Cayla, Florence Leclercq
Calcium score (CS) is a well-known prognostic factor after transcatheter aortic valve implantation (TAVI) performed with first generation prosthesis but few data are available concerning new generation valves. The aim of this study was to evaluate if CS remains a prognostic factor after Sapien 3 and Evolut R valves implantation. Agatston CS was evaluated on multislice computed tomography before TAVI in 346 patients implanted with Sapien XT (n = 61), CoreValve (n = 57) devices, (group 1, n = 118), and with new generation Sapien 3 (n = 147), Evolut R (n = 81) prosthesis, (group 2, n = 228)...
May 15, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29705136/does-translucency-influence-cure-efficiency-and-color-stability-of-resin-based-composites
#10
Vinícius Esteves Salgado, Guilherme Ferreira Rego, Luis Felipe Schneider, Rafael Ratto de Moraes, Larissa Maria Cavalcante
OBJECTIVE: To determine if material's translucency influences the cure efficiency and color stability of resin-based composites (RBCs). METHODS: Four commercially-available RBCs indicated for aesthetic restorations were selected in different translucent/opaque shades: IPS Empress Direct (IED) A3 Dentin, A3 Enamel, Trans 20, and Trans 30; Filtek Z350 XT (FZX) A3D, A3B, A3E, and CT; Estelite ∑ Quick (EQ) OA3, A3, and CE; and Opallis (OP) DA3, EA3, and T-Neutral...
April 25, 2018: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29703265/combined-catwalk-index-an-improved-method-to-measure-mouse-motor-function-using-the-automated-gait-analysis-system
#11
Samuel T Crowley, Kazunori Kataoka, Keiji Itaka
OBJECTIVE: Measuring motor function in mice is important for studying models of spinal cord injury (SCI) or other diseases. Several methods exist based on visual observation of mice moving in an open field. Though these methods require very little equipment, observers must be trained, and the possibility of human error or subjectivity cannot be eliminated. The Noldus CatWalk XT Automated Gait Analysis system assesses mouse motor function by taking high-resolution videos of the mice, with specialized software to measure several aspects of the animal's gait...
April 27, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29688322/conduction-dynamics-after-transcatheter-aortic-valve-implantation-and-implications-for-permanent-pacemaker-implantation-and-early-discharge-the-conduct-study
#12
Lennart van Gils, Sara Baart, Herbert Kroon, Zouhair Rahhab, Nahid El Faquir, Ramón Rodriguez Olivares, Yaar Aga, Anne-Marie Maugenest, Dominic A Theuns, Eric Boersma, Tamas Szili Torok, Peter P De Jaegere, Nicolas M Van Mieghem
Aims: To correlate dynamics in electrical conduction after transcatheter aortic valve implantation (TAVI) with need for permanent pacemaker implantation (PPM) and assess implications for early discharge. Methods and results: Daily electrocardiograms after TAVI were analysed for rhythm and conduction times and were correlated with PPM. Transcatheter aortic valve implantation was performed in 291 consecutive patients with three contemporary transcatheter heart valve designs: Medtronic CoreValve (n = 111), Edwards Sapien XT (n = 29) and Sapien 3 (n = 72), and Boston Lotus (n = 79)...
April 20, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29688174/matched-comparison-of-next-and-early-generation-balloon-expandable-transcatheter-heart-valve-implantations-in-failed-surgical-aortic-bioprostheses
#13
Moritz Seiffert, Hendrik Treede, Joachim Schofer, Axel Linke, Jochen Woehrle, Hardy Baumbach, Julinda Mehilli, Vinayak Bapat, Matheus Simonato, Thomas Walther, Mathias Kullmer, Peter Boekstegers, Stephan Ensminger, Thomas Kurz, Hélène Eltchaninoff, Ardawan Rastan, Nicolas Werner, Arend de Weger, Christian Frerker, Bernward Lauer, Olivier Muller, Brian Whisenant, Arun Thukkani, Giora Weisz, Danny Dvir
AIMS: Transcatheter valve-in-valve implantation (VinV) is established for the treatment of degenerated surgical bioprostheses in patients at high operative risk. Our aim was to report on the first large assessment of VinV with next generation balloon-expandable transcatheter heart valves. METHODS AND RESULTS: 514 patients after SAPIEN XT or SAPIEN 3 VinV were analyzed using an inverse probability of treatment weighting. Standardized clinical and hemodynamic outcomes were compared and core laboratory evaluation of implantation depth was performed...
April 24, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29663496/comparison-of-wear-between-occlusal-splint-materials-and-resin-composite-materials
#14
Marisol Reyes Sevilla, Ruud H Kuijs, Arie Werner, Cornelis J Kleverlaan, Frank Lobbezoo
Tooth wear in bruxing patients often results in a need for treatment with composite restorations. In some cases, bruxing patients receive an occlusal splint as a protective means as well. However, the wear between these opposing materials has not been investigated yet. The aim of this in-vitro study was to assess the wear of different splint materials against resin composite materials. A two-body wear test was conducted using the ACTA wear machine. The materials selected for this study were three composites used for direct restorations (Filtek Z250, CLEARFIL AP-X, and Filtek Supreme XT) and four occlusal splints materials, viz...
April 16, 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29629327/fracture-resistance-of-ceramic-crowns-supported-with-indirect-chair-side-composite-cores
#15
Khalid M Abdelaziz, Cinderella K Keshk, Abdulkhaliq Alshadidi, Salman Mafraq, David F Murchison
Aims and Objectives: To evaluate the influence of indirect chair-side polymerization of resin composite cores on the fracture resistance of overlaying IPS e.max Press crowns. Materials and Methods: Root canals of 60 extracted premolars were prepared to receive #2 fiber posts after the crowns were sectioned 2 mm above the cervical line. In Groups 1-3 ( n = 10 each), posts were luted to the prepared dowel spaces using self-adhesive resin cement. Resin composite cores were then bonded and incrementally built-up using Filtek Z250 XT, Filtek P60, and Filtek P90 resin composites...
January 2018: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/29628471/a-case-of-a-cardiac-resynchronization-therapy-defibrillator-exhibiting-a-lower-and-alternately-variable-basic-rate
#16
Keigo Iwazaki, Toshiya Kojima, Takahide Murasawa, Jun Yokota, Hikaru Tanimoto, Jun Matsuda, Nobuaki Fukuma, Takumi Matsubara, Yu Shimizu, Gaku Oguri, Eriko Hasumi, Hitoshi Kubo, Kyungho Chang, Katsuhito Fujiu, Issei Komuro
A cardiac resynchronization therapy defibrillator (CRT-D) (Medtronic Inc. Protecta XT) was implanted in a 67-year-old man who had cardiac sarcoidosis with extremely low cardiac function. He had ventricular tachycardia which was controlled by catheter ablation, medication and pacing. The programmed mode was DDI, lower rate was 90 beats/minute, paced AV delay was 150 ms, and the noncompetitive atrial pacing (NCAP) function was programmed as 300 ms.After his admission for pneumonia and heart failure, we changed his DDI mode to a DDD mode because he had atrial tachycardia, which led to inadequate bi-ventricular pacing...
April 6, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29627180/transatrial-implantation-of-a-transcatheter-heart-valve-for-severe-mitral-annular-calcification
#17
Fabien Praz, Omar K Khalique, Raymond Lee, Ramesh Veeragandham, Hyde Russell, Mayra Guerrero, Ashequl M Islam, David W Deaton, Tsuyoshi Kaneko, Susheel K Kodali, Martin B Leon, Vinayak Bapat, Hiroo Takayama, Michael A Borger, Isaac George
OBJECTIVE: To assess the outcomes of transatrial implantation of a transcatheter heart valve (THV) for the treatment of mitral valve disease with severe mitral annular calcification (MAC). METHODS: Implantation of a balloon-expandable THV was performed on cardiopulmonary bypass via left atrial exposure in patients considered at risk for left ventricular outflow tract obstruction. The anterior mitral valve leaflet was systematically resected and pledgeted sutures were placed to enhance stability and reduce paravalvular leak...
March 12, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29622987/outcome-of-transcatheter-aortic-valve-implantation-in-high-risk-patients-with-severe-aortic-stenosis
#18
Hamdy Soliman, Khlid Alrabaat, Tarek Aboalaazm, Shaimaa Mostafa, Asaad Samy
Aim: To assess outcome of TAVI in high risk patients with severe symptomatic aortic stenosis. Patients and methods: 40 patients with symptomatic severe aortic stenosis and high risk underwent TAVI with implantation of either Sapien XT valve or Core Valve and followed for 6 months. Device success, cardiovascular mortality, myocardial infarction, stroke, life-threatening bleeding and vascular complications were defined according to Valve Academic Research Consortium definitions...
December 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29617804/feasibility-of-transcatheter-aortic-valve-implantation-in-patients-with-coronary-heights-%C3%A2-7-mm-insights-from-the-transcatheter-aortic-valve-implantation-karlsruhe-tavik-registry
#19
Lars O Conzelmann, Alexander Würth, Gerhard Schymik, Holger Schröfel, Tonic Anusic, Stefanie Temme, Panagiotis Tzamalis, Jan Gerhardus, Chirojit Mukherjee, Bernd-Dieter Gonska, Claus Schmitt, Uwe Mehlhorn
OBJECTIVES: Transcatheter aortic valve implantation (TAVI) in patients with low coronary heights is generally denied but is not impossible. Information about these high-risk procedures is sparse. METHODS: Since May 2008, data of more than 3000 patients who had TAVI were prospectively collected in the institutional TAVI Karlsruhe registry. Characteristics, peri- and postoperative outcome of patients with low coronary heights of ≤7 mm were analysed according to the Valve Academic Research Consortium-2...
April 2, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29610447/very-late-migration-of-balloon-expandable-transcatheter-aortic-valve
#20
Ankur Kalra, Eleonora Avenatti, Ponraj Chinnadurai, Michael J Reardon, Neal S Kleiman, Stephen H Little, Colin M Barker
Color-flow Doppler transesophageal echocardiography during valve-in-valve TAVR illustrates the placement of a 23 mm Edwards Sapien 3 valve carefully positioned within a displaced 23 mm Edwards Sapien XT valve.
April 2018: Journal of Invasive Cardiology
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