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https://www.readbyqxmd.com/read/28647802/a-case-of-sapien-xt-valve-fallen-into-left-ventricle-during-valve-in-valve-transcatheter-aortic-valve-implantation
#1
Shigeki Koizumi, Natsuhiko Ehara, Kenta Nishiya, Tadaaki Koyama
Late transcatheter heart valve embolization is a rare but life-threatening complication of transcatheter aortic valve implantation. Surgical intervention is performed for most cases, but some cases were treated by valve-in-valve transcatheter aortic valve implantation. We describe a patient in whom a 29-mm Edwards SAPIEN XT valve migrated into the left ventricular outflow tract 41 days after the initial implantation. We tried to perform valve-in-valve transcatheter aortic valve implantation using a transfemoral approach...
June 24, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28643214/new-generation-devices-for-transfemoral-transcatheter-aortic-valve-replacement-are-superior-compared-with-last-generation-devices-with-respect-to-varc-2-outcome
#2
Julia Seeger, Birgid Gonska, Wolfgang Rottbauer, Jochen Wöhrle
New generation devices for transcatheter aortic valve replacement have been optimized to improve clinical outcome. We compared procedural, in-hospital, 30 days and 12 months outcome of the new generation repositionable Boston Lotus Valve and the balloon-expandable Edwards Sapien 3 valve with the last generation self-expandable Medtronic CoreValve and the balloon-expandable Edwards Sapien XT. Between 2010 and 2015 consecutive patients treated with the Medtronic CoreValve (N = 100), Edwards Sapien XT (N = 100), Edwards Sapien S3 (N = 100) and Boston Lotus device (N = 100) were enrolled...
June 22, 2017: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/28642915/pre-treating-dentin-with-chlorhexadine-and-cpp-acp-self-etching-and-universal-adhesive-systems
#3
Ricardo Alves Dos Santos, Eliane Alves de Lima, Marcos Antônio Japiassu Resende Montes, Rodivan Braz
Objective: The aim of the present study was to compare the effect of pre-treating dentin with chlorhexidine, at concentrations of 0.2% and 2%, and remineralizing paste containing CPP-ACP (MI Paste - GC) on the bond strength of adhesive systems. Material and methods: In total, 80 slides of dentin were used. These slides were 2 mm thick and were obtained from bovine incisors. Standard cavities were created using diamond bur number 3131. In the control groups, a Scotchbond Universal Adhesive (SUA) self-etching adhesive system of 3M ESPE and a Clearfil SE Bond (CSE) adhesive system of Kuraray were applied, following the manufacturer's instructions...
December 2016: Acta Biomaterialia Odontologica Scandinavica
https://www.readbyqxmd.com/read/28642057/novel-multifunctional-dental-cement-to-prevent-enamel-demineralization-near-orthodontic-brackets
#4
Yansong Ma, Ning Zhang, Michael D Weir, Yuxing Bai, Hockin H K Xu
OBJECTIVES: White spot lesions due to biofilm acid-induced enamel demineralization are prevalent in orthodontic treatments. The aim of this study was to develop a novel bioactive multifunctional cement with protein-repellent, antibacterial and remineralizing capabilities, and investigate the effects on enamel hardness and lesion depth in vitro for the first time. MATERIALS AND METHODS: 2-Methacryloyloxyethyl phosphorylcholine (MPC), dimethylaminohexadecyl methacrylate (DMAHDM), and nanoparticles of amorphous calcium phosphate (NACP) were incorporated into a resin-modified glass ionomer (RMGI)...
June 19, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28640749/enamel-shear-bond-strength-of-different-primers-combined-with-an-orthodontic-adhesive-paste
#5
Julia H Seeliger, Ute U Botzenhart, Tomasz Gedrange, Karol Kozak, Lukas Stepien, Monika Machoy
AIM: The aim of this study was a comparison of shear bond strength (SBS) on tooth enamel of different primers combined with the adhesive paste Transbond XT. MATERIALS AND METHODS: Forty bovine teeth were used in order to create 40 test blocks. The blocks were divided into four groups of 10 blocks each: group A - sample primer (SP); group B - Opal Seal (OS); group C - Transbond Plus SEP (TSEP); group D - Transbond XT Primer (TXT). After surface preparation and application of the primer, respectively, two stainless steel brackets were fixed on each tooth by using Transbond XT...
June 22, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28638550/shear-bond-strength-of-orthodontic-metal-brackets-to-aged-composite-using-three-primers
#6
Ali Tayebi, Farnoosh Fallahzadeh, Marzieh Morsaghian
BACKGROUND: This study aimed to assess the effect of surface preparation with sandblasting and diamond bur along with the use of three primers on shear bond strength (SBS) of metal brackets to aged composite. MATERIAL AND METHODS: In this in vitro, experimental study, 60 Filtek Z250 composite discs were fabricated (10×2mm), immersed in distilled water for 24 hours and subjected to 5000 thermal cycles. They were randomly divided into two groups (n=30) of sandblasting with aluminum oxide particles for 10 seconds and surface roughening with bur...
June 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28632404/medial-and-lateral-rectus-muscle-insertion-distance-and-width-in-esotropia-and-exotropia-patients
#7
Leyla Niyaz, Ozlem Eski Yucel, Adem Gul
PURPOSE: The hypothesis that the extraocular muscle insertion distance and muscle width may be associated with the type and size of deviation was tested. METHODS: This was a prospective study of 129 patients who had surgery for horizontal strabismus or retinal detachment. The insertion distances and widths of the medial rectus (MR) and lateral rectus (LR) muscles were measured intraoperatively in esotropia, exotropia, and buckling surgery (control group) patients...
June 20, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28631631/ki-67-evaluation-in-breast-cancer-the-daily-diagnostic-practice
#8
Lukasz Fulawka, Agnieszka Halon
CONTEXT: Breast cancer is the most common malignancy in females. It is routinely classified according to the WHO histological typing. However, there is also a molecular classification of breast cancer which is routinely substituted with surrogate subtypes based on expression of estrogen, progesterone, and human epidermal growth factor receptor 2 receptors and proliferation index (PI). PI is defined as the percentage of Ki-67-positive cells among overall cell population. The method commonly applied by pathologists to determine PI is visual scoring of the sample...
April 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28622581/assessment-of-atherosclerotic-luminal-narrowing-of-coronary-arteries-based-on-morphometrically-generated-visual-guides
#9
Rolf F Barth, David A Kellough, Patricia Allenby, Luke E Blower, Scott H Hammond, Greg M Allenby, L Maximilian Buja
BACKGROUND AND AIMS: Determination of the degree of stenosis of atherosclerotic coronary arteries is an important part of postmortem examination of the heart, but, unfortunately, estimation of the degree of luminal narrowing can be imprecise and tends to be approximations. Visual guides can be useful to assess this, but earlier attempts to develop such guides did not employ digital technology. Using this approach, we have developed two computer-generated morphometric guides to estimate the degree of luminal narrowing of atherosclerotic coronary arteries...
May 30, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28606889/parallel-suture-technique-with-proglide-a-novel-method-for-management-of-vascular-access-during-transcatheter-aortic-valve-implantation-tavi
#10
Ilka Ott, Anupama Shivaraju, Nina R Schäffer, Antonio H Frangieh, Jonathan Michel, Oliver Husser, Christian Hengstenberg, Patrick Mayr, Roisin Colleran, Constanza Pellegrini, Salvatore Cassese, Massimilliano Fusaro, Heribert Schunkert, Adnan Kastrati, Albert M Kasel
AIMS: Aim of this study was to evaluate vascular complications using the "parallel suture technique" in patients receiving Edwards SAPIEN XT (SXT) or SAPIEN S3 (S3) transcatheter heart valve (THV). METHODS AND RESULTS: Two hundred consecutive patients with symptomatic severe aortic stenosis treated with TF-TAVI were included in this study where the "parallel suture technique" was applied for vascular access site closure. This was achieved by placing the sutures medial and lateral to the puncture site...
June 13, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28606674/transcatheter-aortic-valve-implantation-in-patients-with-an-extremely-small-native-aortic-annulus-the-ocean-tavi-registry
#11
Fumiaki Yashima, Masanori Yamamoto, Makoto Tanaka, Ryo Yanagisawa, Takahide Arai, Hideyuki Shimizu, Keiichi Fukuda, Yusuke Watanabe, Toru Naganuma, Shinichi Shirai, Motoharu Araki, Norio Tada, Futoshi Yamanaka, Kentaro Hayashida
BACKGROUND: Transcatheter aortic valve implantation (TAVI) has been reported to be advantageous over surgical aortic valve replacement owing to the low incidence of prosthesis-patient mismatch (PPM) and large effective orifice area (EOA). However, data on TAVI for extremely small annuli are limited. The present study aimed to compare post-procedural hemodynamics and morphology between 20-mm and 23-mm Sapien XT (SXT) transcatheter heart valves (THVs) with extremely small annuli (<314mm(2))...
August 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28597998/a-novel-mechanical-mitral-valve-replacement-using-sapien-xt
#12
Megan Koehle, Justin A Strote, Mark Guadagnoli, J Bradley Oldemeyer
PATIENT PRESENTATION: We report the case of a 66 year old female who presented to our institution fourteen years after receiving a St. Jude Mechanical Mitral Valve Replacement. She presented in refractory NYHA class IV congestive heart failure with comorbidities of acute renal failure, liver failure, and mental status changes. She was found to have immobility of one of the mitral valve disks with resultant severe mitral stenosis with a mean pressure gradient of 12 mmHg. EVALUATION AND MANAGEMENT: The patient was found to have an STS predicted mortality of 39% with redo surgical MVR, and evaluation by the valve team led to a recommendation of a hybrid surgical and transcatheter procedure...
June 9, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28582640/the-causes-of-thrombocytopenia-after-transcatheter-aortic-valve-implantation
#13
Maciej Mitrosz, Remigiusz Kazimierczyk, Bozena Sobkowicz, Ewa Waszkiewicz, Pawel Kralisz, Marek Frank, Jaroslaw Piszcz, Marzenna Galar, Slawomir Dobrzycki, Wlodzimierz J Musial, Tomasz Hirnle, Karol A Kaminski, Agnieszka M Tycinska
INTRODUCTION: Even though thrombocytopenia following transcatheter aortic valve implantation (TAVI) has been described, further investigation of this phenomenon is needed. AIMS: To determine which factors may explain the fall in platelet count that occurs after implantation of a TAVI device, including markers of platelet and blood coagulation activation. MATERIAL AND METHODS: 32 patients without previous indications for dual antiplatelet therapy (mean age 78...
May 26, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/28582580/transaortic-transcatheter-aortic-valve-implantation-using-sapien-xt-or-sapien-3-valves-in-the-route-registry%C3%A2
#14
Mauro Romano, Derk Frank, Riccardo Cocchieri, Dariusz Jagielak, Nikolaos Bonaros, Marco Aiello, Joel Lapeze, Mika Laine, Sidney Chocron, Douglas Muir, Walter Eichinger, Matthias Thielmann, Louis Labrousse, Kjell Arne Rein, Jean-Philippe Verhoye, Gino Gerosa, Hardy Baumbach, Cornelia Deutsch, Peter Bramlage, Martin Thoenes, Vinayak Bapat
OBJECTIVES: Transaortic (TAo) access for transcatheter aortic valve implantation (TAVI) is an alternative to the conventional transfemoral or transapical routes. Data comparing the characteristics and outcomes of TAo-TAVI using the SAPIEN XT and SAPIEN 3 heart valves are scarce. The objective of the current analysis was to provide such information. METHODS: ROUTE is an international, prospective, observational registry. Patients with severe calcific aortic stenosis scheduled for TAo-TAVI with an Edwards SAPIEN XT or a SAPIEN 3 heart valve were consecutively enrolled at 22 centres across Europe between February 2013 and February 2015...
June 5, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28571259/comparative-evaluation-of-two-bis-gma-based-orthodontic-bonding-adhesives-a-randomized-clinical-trial
#15
Christine Samantha, Shantha Sundari, Shyamala Chandrasekhar, Gautham Sivamurty, Saravana Dinesh
INTRODUCTION: Of the various orthodontic bonding materials, orthofix is a fairly new entrant into this field. This material was exclusively introduced for orthodontic bonding purposes; however, the application of this material for orthodontic purpose has not been scientifically evaluated so far. AIM: The aim of the present study was to evaluate by an in-vivo double blinded split mouth rando mized clinical trial, the overall bond failure rates of two Bis-GMA based composite materials namely Transbond XT and Orthofix...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28569157/effects-of-sesamin-on-chondroitin-sulfate-proteoglycan-synthesis-induced-by-interleukin-1beta-in-human-chondrocytes
#16
Warunee Srisuthtayanont, Dumnoensun Pruksakorn, Prachya Kongtawelert, Peraphan Pothacharoen
BACKGROUND: Numerous studies have reported on the health benefits of sesamin, a major lignin found in sesame (S. indicum) seeds. Recently, sesamin was shown to have the ability to promote chondroitin sulfate proteoglycan synthesis in normal human chondrocytes. This study assesses the anti-inflammatory effect of sesamin on proteoglycans production in 3D chondrocyte cultures. METHODS: To evaluate the effects of sesamin on IL-1β-treated human articular chondrocytes (HAC) pellets, the pellets were pre-treated with IL-1β then cultured in the presence of various concentrations of sesamin for 21 days...
May 31, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28567700/different-impact-of-aortic-regurgitation-assessed-by-aortic-root-angiography-after-transcatheter-aortic-valve-implantation-according-to-baseline-left-ventricular-ejection-fraction-and-n-terminal-pro-b-type-natriuretic-peptide
#17
Hidehiro Kaneko, Frank Hoelschermann, Thomas Schau, Grit Tambor, Michael Neuss, Christian Butter
Transcatheter aortic valve implantation (TAVI) is an alternative therapeutic option for severe aortic stenosis. Aortic regurgitation (AR) is commonly observed after TAVI and increases the mortality rate. We hypothesized that the influence of significant AR, defined as that more severe than mild AR, on survival rate after TAVI might differ according to the baseline left ventricular ejection fraction (LVEF) and N-terminal pro-B-type natriuretic peptide (NT-pro BNP) level. We categorized 856 patients who underwent transfemoral TAVI into 2 groups according to their baseline LVEF (<40 and ≥40%) and NT-pro BNP levels (≤5000 and >5000 pg/mL)...
May 31, 2017: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/28561856/la-iii-biodistribution-profiles-from-intravenous-and-oral-dosing-of-two-lanthanum-complexes-la-dpp-3-and-la-xt-and-evaluation-as-treatments-for-bone-resorption-disorders
#18
D M Weekes, J F Cawthray, M Rieder, J Syeda, M Ali, E Wasan, T I Kostelnik, B O Patrick, A Panahifar, A Al-Dissi, D Cooper, K M Wasan, C Orvig
Trivalent lanthanum (La(3+)) has the potential to treat bone resorption disorders (such as osteoporosis) by eliciting a bone-building response in the cells which control skeletal remodelling. Because La(3+) suffers from extremely poor intestinal absorption, specifically designed chelators are required in order that a biologically active form of lanthanum can be administered orally. Two such chelators, 1,2-dimethyl-3-hydroxy-4-pyridinone (Hdpp) and bis-{[bis(carboxymethyl)amino]methy}phosphinic acid (H5XT), have previously been the subjects of extensive physical, in vitro, and in vivo testing as the tris- and mono-lanthanum(iii) complexes La(dpp)3 and La(XT), respectively...
May 31, 2017: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/28558124/comparison-of-glass-slides-and-various-digital-slide-modalities-for-cytopathology-screening-and-interpretation
#19
Matthew G Hanna, Sara E Monaco, Jacqueline Cuda, Juan Xing, Ishtiaque Ahmed, Liron Pantanowitz
BACKGROUND: Whole-slide imaging in cytology is limited when glass slides are digitized without z-stacks for focusing. Different vendors have started to provide z-stacking solutions to overcome this limitation. The Panoptiq imaging system allows users to create digital files combining low-magnification panoramic images with regions of interest (ROIs) that are imaged with high-magnification z-stacks. The aim of this study was to compare such panoramic images with conventional whole-slide images and glass slides for the tasks of screening and interpretation in cytopathology...
May 30, 2017: Cancer
https://www.readbyqxmd.com/read/28552399/evaluation-of-lactate-white-blood-cell-count-neutrophil-count-procalcitonin-and-immature-granulocyte-count-as-biomarkers-for-sepsis-in-emergency-department-patients
#20
Brad S Karon, Nicole V Tolan, Amy M Wockenfus, Darci R Block, Nikola A Baumann, Sandra C Bryant, Casey M Clements
BACKGROUND: Lactate, white blood cell (WBC) and neutrophil count, procalcitonin and immature granulocyte (IG) count were compared for the prediction of sepsis, and severe sepsis or septic shock, in patients presenting to the emergency department (ED). METHODS: We prospectively enrolled 501 ED patients with a sepsis panel ordered for suspicion of sepsis. WBC, neutrophil, and IG counts were measured on a Sysmex XT-2000i analyzer. Lactate was measured by i-STAT, and procalcitonin by Brahms Kryptor...
May 25, 2017: Clinical Biochemistry
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