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https://www.readbyqxmd.com/read/28108576/dual-source-computed-tomography-based-analysis-of-stent-performance-its-association-with-valvular-calcification-and-residual-aortic-regurgitation-after-implantation-of-a-balloon-expandable-transcatheter-heart-valve
#1
Julius Gerstmeyer, Maximilian Kütting, Buntaro Fujita, Annika Schuhbäck, Martin Arnold, Jochen Börgermann, Stephan Achenbach, Ulrich Steinseifer, Jan Gummert, Stephan Ensminger
OBJECTIVES: The aim of this study was to investigate the mutual influence of valvular calcifications and transcatheter aortic valve stent geometry during and after implantation of a balloon-expandable SAPIEN(®)/SAPIEN XT(®) prostheses. Aortic valve calcification has been linked with adverse complications after transcatheter aortic valve implantation (TAVI). However, little is known about the fate of the calcifications after TAVI as well as its influence on transcatheter heart valve geometry...
January 20, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28106001/impact-of-femoral-artery-puncture-using-digital-subtraction-angiography-and-road-mapping-on-vascular-and-bleeding-complications-after-transfemoral-transcatheter-aortic-valve-implantation
#2
Mohamed El-Mawardy, Bettina Schwarz, Martin Landt, Dmitriy Sulimov, Julia Kebernik, Abdelhakim Allali, Bjoern Becker, Ralph Toelg, Gert Richardt, Mohamed Abdel-Wahab
AIMS: The use of large-diameter sheaths carries the risk of significant vascular and bleeding complications after transfemoral transcatheter aortic valve implantation (TAVI). In this analysis, we sought to assess the impact of a modified femoral artery puncture technique using digital subtraction angiography (DSA) and road mapping during transfemoral TAVI on periprocedural vascular and bleeding events. METHODS AND RESULTS: This is a retrospective analysis of transfemoral TAVI patients included in a prospective institutional database...
January 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28104190/in%C3%A2-vitro-coronary-flow-after-transcatheter-aortic-valve-in-valve-implantation-a-comparison-of-2-valves
#3
Sina Stock, Michael Scharfschwerdt, Roza Meyer-Saraei, Doreen Richardt, Efstratios I Charitos, Hans-Hinrich Sievers, Thorsten Hanke
BACKGROUND: Transcatheter aortic valve-in-valve implantation (TAVI-ViV) is an evolving treatment strategy for degenerated surgical aortic valve bioprostheses (SAVBs). However, there is some concern regarding coronary obstruction, especially after TAVI-ViV in calcified SAVBs with externally mounted leaflets. We investigated in vitro coronary flow and hydrodynamics after TAVI-ViV using 2 modern SAVBs with externally and internally mounted leaflets. METHODS: Aortic root models including known risk factors for coronary obstruction served for the implantation of SAVBs with either externally mounted leaflets (St Jude Trifecta, size 25) or internally mounted leaflets (Edwards Perimount Magna Ease, size 25)...
February 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28100877/transcatheter-aortic-valve-implantation-with-different-valve-designs-for-severe-device-landing-zone-calcification
#4
Yoshio Maeno, Yigal Abramowitz, Yoshio Kazuno, Hiroyuki Kawamori, Geeteshwar Mangat, Nobuyuki Takahashi, Tarun Chakravarty, Mamoo Nakamura, Wen Cheng, Hasan Jilaihawi, Raj R Makkar
Severe device landing zone calcification (DLZ-CA) predicted paravalvular leak (PVL) and post-dilatation (PD) after transcatheter aortic valve implantation (TAVI). The aim of this study was to determine the influence of DLZ-CA on PVL or PD rates after SAPIEN XT (XT) versus CoreValve (CV).We analyzed patients undergoing TAVI who had severe DLZ-CA. Severe DLZ-CA defined the upper left ventricular outflow tract calcification; the cross-sectional region 2 mm inferior to the annular plane. PVL was evaluated at 30days using transthoracic echocardiography...
January 17, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28094151/comparison-of-the-bd-max-mrsa-xt-to-the-cepheid%C3%A2-xpert%C3%A2-mrsa-assay-for-the-molecular-detection-of-methicillin-resistant-staphylococcus-aureus-from-nasal-swabs
#5
Sanjay R Mehta, Jasmine Estrada, Juan Ybarra, Joshua Fierer
INTRODUCTION: Variation in MRSA genotypes may affect the sensitivity of molecular assays to detect this organism. METHODS: We compared 2 commonly used screening assays, the Cepheid™ Xpert® MRSA and the BD MAX™ MRSA XT on consecutively obtained nasal swabs from 479 subjects. Specimens giving discordant results were subjected to additional microbiologic and molecular testing. RESULTS: Six hundred forty-two (97.6%) of the 658 test results were concordant...
December 16, 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28086858/the-influence-of-adding-modified-zirconium-oxide-titanium-dioxide-nano-particles-on-mechanical-properties-of-orthodontic-adhesive-an-in-vitro-study
#6
Nayef H Felemban, Mohamed I Ebrahim
BACKGROUND: The purpose of this in-vitro study was to examine the effect of incorporating different concentrations of Zirconium oxide-Titanium dioxide (ZrO2-TiO2) nanoparticles, which can have antibacterial properties, on the mechanical properties of an orthodontic adhesive. METHODS: ZrO2-TiO2 (Zirconium oxide, HWNANO, Hongwu International Group Ltd, China) -Titanium dioxide, Nanoshell, USA) nanopowder were incorporated into orthodontic adhesive (Transbond XT, 3 M Unitek, Monrovia, USA) with different concentrations (0...
January 13, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28077886/effect-of-dental-chair-light-on-enamel-bonding-of-orthodontic-brackets-using-light-cure-based-adhesive-system-an-in-vitro-study
#7
Anil Tiwari, Tarulatha Shyagali, Sarvraj Kohli, Rishi Joshi, Abhishek Gupta, Rana Tiwari
AIM: The aim of this in vitro study was to evaluate the influence of the Dental chair light on the bond strength of light cured composite resin. MATERIALS AND METHODS: Sixty therapeutically extracted human premolar teeth were randomly allocated to two groups of 30 specimens each. In both groups light cured composite resin (Transbond XT) and MBT premolar metal brackets (3M Unitek) was used to bond brackets. In group I and II light curing was done using Light-emitting diode light curing units without and with the dental chair light respectively...
October 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28076496/evaluation-of-dentin-hypersensitivity-treatment-with-glass-ionomer-cements-a-randomized-clinical-trial
#8
Marina de Matos Madruga, Adriana Fernandes da Silva, Wellington Luiz de Oliveira da Rosa, Evandro Piva, Rafael Guerra Lund
A randomized, double-blind, split-mouth clinical trial was performed compared the desensitizing efficacy of the resin-modified glass ionomer cement (GIC) ClinproTM XT (3M ESPE, Minnesota, USA) and the conventional GIC Vidrion R (SS White, Gloucester, UK) in a 6-month follow-up. Subjects were required to have at least two teeth with dentin hypersensitivity. Teeth were divided at random into 2 groups, one group received Clinpro XT and the other conventional GIC Vidrion R. Treatments were assessed by tactile and air blast tests using Visual Analogue Scale (VAS) at baseline, after 20 minutes, and at 7, 15, 21, 30, 90 and 180 days post-treatment...
January 5, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28070241/comparison-between-the-sapien-s3-and-the-sapien-xt-transcatheter-heart-valves-a-single-center-experience
#9
Fadi J Sawaya, Marco Spaziano, Thierry Lefèvre, Andrew Roy, Phillippe Garot, Thomas Hovasse, Antoinette Neylon, Hakim Benamer, Mauro Romano, Thierry Unterseeh, Marie-Claude Morice, Bernard Chevalier
AIM: To investigate the clinical outcomes of transcatheter aortic valve implantation (TAVI) with the SAPIEN 3 transcatheter heart valve (S3-THV) vs the SAPIEN XT valve (XT-THV). METHODS: We retrospectively analyzed 507 patients that underwent TAVI with the XT-THV and 283 patients that received the S3-THV at our institution between March 2010 and December 2015. RESULTS: Thirty-day mortality (3.5% vs 8.7%; OR = 0.44, P = 0.21) and 1-year mortality (25...
December 26, 2016: World Journal of Cardiology
https://www.readbyqxmd.com/read/28068189/intrapulpal-temperature-increase-during-er-yag-laser-aided-debonding-of-ceramic-brackets
#10
Hilal Yilanci, Zeynep Beyza Yildirim, Sabri Ilhan Ramoglu
OBJECTIVE: The purpose of this study was to evaluate the temperature changes in the pulp chamber while using a newly introduced application of Er:YAG laser to debond ceramic brackets in a study model with a pulpal circulation with and without thermocycled samples. BACKGROUND DATA: An esthetic alternative to stainless steel brackets, ceramic brackets have been proposed. However, because of their low fracture resistance and high bond strengths, ceramic brackets can cause a problem when they are being removed using conventional techniques...
January 9, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28066611/performance-of-a-lateral-flow-immunochromatography-test-for-the-rapid-diagnosis-of-active-tuberculosis-in-a-large-multicentre-study-in-areas-with-different-clinical-settings-and-tuberculosis-exposure-levels
#11
Selene Manga, Rocio Perales, Maria Reaño, Lia D'Ambrosio, Giovanni Battista Migliori, Massimo Amicosante
BACKGROUND: Tuberculosis (TB) continues to cause an outsized burden of morbidity and mortality worldwide, still missing efficient and largely accessible diagnostic tools determining an appropriate control of the disease. Serological tests have the potentially to impact TB diagnosis, in particular in extreme clinical settings. METHODS: The diagnostic performances of the TB-XT HEMA EXPRESS (HEMA-EXPRESS) immunochromatographic rapid test for active TB diagnosis, based on use of multiple Mycobacterium tuberculosis (MTB) specific antigens, have been evaluated in a large study multicentre TB case-finding study, in populations with different exposure level to TB...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28050507/shear-bond-strength-of-ceramic-brackets-with-different-base-designs-comparative-in-vitro-study
#12
Mohd Younus Ansari, Deepak K Agarwal, Ankur Gupta, Preeti Bhattacharya, Juhi Ansar, Ravi Bhandari
INTRODUCTION: Knowledge about the Shear Bond Strength (SBS) of ceramic brackets with different base design is essential as it affects bond strength to enamel. AIM: The aim of the present study was to evaluate and compare the effect of base designs of different ceramic brackets on SBS, and to determine the fracture site after debonding. MATERIALS AND METHODS: Four groups of ceramic brackets and one group of metal brackets with different base designs were used...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28044267/late-paravalvular-aortic-regurgitation-migration-of-the-valve-or-late-recoil
#13
Ashkan Karimi, Negiin Pourafshar, Ki E Park, Calvin Y Choi, Kiran Mogali, Wade W Stinson, Eddie W Manning, Anthony A Bavry
A 79-year-old man underwent trans-catheter aortic valve replacement for symptomatic severe aortic stenosis with a 26-mm Edwards SAPIEN XT valve. Immediately after valve deployment there was moderate amount of paravalvular leak. Post-dilation was performed with an additional 2 cc of volume, and the paravalvular leak was reduced to trace. Nine months later, trans-thoracic echocardiography revealed moderate to severe paravalvular leak and possible aortic migration of the valve. The patient was brought back for the treatment of the paravalvular leak which was suspected to be due to valve migration...
January 2, 2017: Cardiology and Therapy
https://www.readbyqxmd.com/read/28043590/use-of-wgs-in-mycobacterium-tuberculosis-routine-diagnosis
#14
Daniela M Cirillo, Andrea M Cabibbe, Maria Rosaria De Filippo, Alberto Trovato, Tullia Simonetti, Gian Maria Rossolini, Enrico Tortoli
OBJECTIVE/BACKGROUND: Whole Genome Sequencing (WGS) is becoming affordable with overall costs comparable to other tests currently in use to perform the diagnosis of drug-resistant tuberculosis (TB) and cluster analysis. The WGS approach allows an "all-in-one" approach providing results on expected sensitivity of the strains, genetic background, epidemiological data, and indication of risk of laboratory cross-contamination. METHODS: Although ideal, WGS from the direct diagnostic specimen is not yet standardized, and to date the two most promising approaches are WGS from early positive liquid culture and targeted sequencing from diagnostic specimens using Next-Generation Technology...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28029207/prospective-comparison-between-three-tavr-devices-acurate-neo-vs-corevalve-vs-sapien-xt-a-single-heart-team-experience-in-patients-with-severe-aortic-stenosis
#15
Tannas Jatene, Antonio Castro-Filho, Rafael A Meneguz-Moreno, Dimytri A Siqueira, Alexandre A C Abizaid, Auristela I O Ramos, Magaly Arrais, David C S Le Bihan, Rodrigo B M Barretto, Adriana C Moreira, Amanda G M R Sousa, J Eduardo Sousa
OBJECTIVE: We sought to compare the new transcatheter aortic valve replacement (TAVR) device ACURATE neo (ACT) with the already established CoreValve (MCV) and SAPIEN XT (SXT) for the treatment of severe aortic stenosis (AS). BACKGROUND: Very few data on TAVR devices are available beyond MCV and SAPIEN and there is no previous study comparing ACT with MCV and SXT. METHODS: We prospectively evaluated consecutive patients who underwent transfemoral TAVR for the treatment of severe AS...
December 28, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28028692/in-vitro-hydrodynamic-assessment-of-a-new-transcatheter-heart-valve-concept-the-triskele
#16
Benyamin Rahmani, Spyros Tzamtzis, Rose Sheridan, Michael J Mullen, John Yap, Alexander M Seifalian, Gaetano Burriesci
This study presents the in vitro hydrodynamic assessment of the TRISKELE, a new system suitable for transcatheter aortic valve implantation (TAVI), aiming to mitigate the procedural challenges experienced with current technologies. The TRISKELE valve comprises three polymeric leaflet and an adaptive sealing cuff, supported by a novel fully retrievable self-expanding nitinol wire frame. Valve prototypes were manufactured in three sizes of 23, 26, and 29 mm by automated dip-coating of a biostable polymer, and tested in a hydrodynamic bench setup in mock aortic roots of 21, 23, 25, and 27 mm annulus, and compared to two reference valves suitable for equivalent implantation ranges: Edwards SAPIEN XT and Medtronic CoreValve...
December 27, 2016: Journal of Cardiovascular Translational Research
https://www.readbyqxmd.com/read/28018748/laboratory-investigation-of-i-salmonella-enterica-i-serovar-poona-outbreak-in-california-comparison-of-pulsed-field-gel-electrophoresis-pfge-and-whole-genome-sequencing-wgs-results
#17
Varvara K Kozyreva, John Crandall, Ashley Sabol, Alyssa Poe, Peng Zhang, Jeniffer Concepción-Acevedo, Morgan N Schroeder, Darlene Wagner, Jeffrey Higa, Eija Trees, Vishnu Chaturvedi
INTRODUCTION: Recently, Salmonella enterica serovar Poona caused a multistate outbreak, with 245 out of 907 cases occurring in California. We report a comparison of pulsed-field gel electrophoresis (PFGE) results with whole genome sequencing (WGS) for genotyping of Salmonella Poona isolates. METHODS: CA Salmonella Poona isolates, collected from July to August 2015, were genotyped by PFGE using XbaI restriction enzyme. WGS was done using Nextera XT library kit with 2x300 bp or 2x250 bp sequencing chemistry on the Illumina MiSeq Sequencer...
November 22, 2016: PLoS Currents
https://www.readbyqxmd.com/read/28017712/incidence-predictors-and-mid-term-outcomes-of-possible-leaflet-thrombosis-after-tavr
#18
Ryo Yanagisawa, Kentaro Hayashida, Yoshitake Yamada, Makoto Tanaka, Fumiaki Yashima, Taku Inohara, Takahide Arai, Takashi Kawakami, Yuichiro Maekawa, Hikaru Tsuruta, Yuji Itabashi, Mitsushige Murata, Motoaki Sano, Kazuma Okamoto, Akihiro Yoshitake, Hideyuki Shimizu, Masahiro Jinzaki, Keiichi Fukuda
OBJECTIVES: This study sought to clarify the incidence and predictors of hypoattenuated leaflet thickening (HALT) and mid-term outcomes after transcatheter aortic valve replacement. BACKGROUND: HALT detected on multidetector computed tomography (MDCT) scanning raised concerns about possible subclinical leaflet thrombosis. METHODS: We studied 70 of 100 consecutive patients from a single-center registry who underwent implantation with the Edwards SAPIEN-XT device...
December 8, 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28005247/efficacy-and-safety-of-low-dose-capecitabine-plus-docetaxel-versus-single-agent-docetaxel-in-patients-with-anthracycline-pretreated-her2-negative-metastatic-breast-cancer-results-from-the-randomized-phase-iii-jo21095-trial
#19
Daigo Yamamoto, Nobuaki Sato, Yoshiaki Rai, Yutaka Yamamoto, Mitsue Saito, Hiroji Iwata, Norikazu Masuda, Shoji Oura, Junichiro Watanabe, Satoshi Hattori, Yoshimasa Matsuura, Katsumasa Kuroi
PURPOSE: The randomized phase III JO21095 trial compared the efficacy and safety of low-dose capecitabine plus docetaxel combination therapy (XT) versus single-agent administration of docetaxel in anthracycline-pretreated HER2-negative metastatic breast cancer. METHODS: Patients were randomized to either low-dose XT (capecitabine 825 mg/m(2) twice daily, days 1-14; docetaxel 60 mg/m(2), day 1 every 3 weeks) or docetaxel (70 mg/m(2), day 1 every 3 weeks). The primary objective was to demonstrate superior progression-free survival (PFS) with low-dose XT versus single-agent docetaxel...
February 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28002695/clinical-effectiveness-of-different-polishing-systems-and-self-etch-adhesives-in-class-v-composite-resin-restorations-two-year-randomized-controlled-clinical-trial
#20
J-H Jang, H-Y Kim, S-M Shin, C-O Lee, D S Kim, K-K Choi, S-Y Kim
The aim of this randomized controlled clinical trial was to compare the clinical effectiveness of different polishing systems and self-etch adhesives in class V composite resin restorations. A total of 164 noncarious cervical lesions (NCCLs) from 35 patients were randomly allocated to one of four experimental groups, each of which used a combination of polishing systems and adhesives. The two polishing systems used were Sof-Lex XT (Sof), a multistep abrasive disc, and Enhance/Pogo (EP), a simplified abrasive-impregnated rubber instrument...
January 2017: Operative Dentistry
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