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https://www.readbyqxmd.com/read/28797433/periprocedural-myocardial-injury-depends-on%C3%A2-transcatheter-heart-valve-type-but-does%C3%A2-not%C3%A2-predict-mortality-in-patients-after-transcatheter-aortic-valve-replacement
#1
Anja Stundl, Regina Schulte, Hannah Lucht, Marcel Weber, Alexander Sedaghat, Jasmin Shamekhi, Berndt Zur, Eberhard Grube, Fritz Mellert, Armin Welz, Rolf Fimmers, Georg Nickenig, Nikos Werner, Jan-Malte Sinning
OBJECTIVES: The aims of this study were to determine plasma elevations of biomarkers of myocardial injury associated with transfemoral (TF) transcatheter aortic valve replacement (TAVR) and to evaluate their prognostic value. BACKGROUND: Increases in biomarkers of myocardial injury are a common finding after TAVR, but their clinical significance is unclear. METHODS: In 756 consecutive TF TAVR patients, cardiac high-sensitivity troponin I (hsTnI) and creatine kinase MB (CK-MB) levels were measured at pre-defined time points to assess the occurrence of myocardial injury (defined as 15 times the upper reference limit for hsTnI [≥1...
August 14, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28796570/pedigree-analysis-of-familial-primary-concomitant-horizontal-strabismus-in-northern-india
#2
Zia Chaudhuri, Jibin John, Satinder Aneja, B K Thelma
PURPOSE: Familial clustering of common forms of primary strabismus like esotropia (ET) and exotropia (XT) is observed in a proportion of the strabismus cohort. The genetic components of this remain unidentified. Linkage studies have demonstrated susceptibility locus for primary strabismus at the STBMS1 locus on 7p22.1 as well as other loci on 4q28.3 and 7q31.2. Recently next generation sequencing (NGS) technology has emerged as a powerful tool in discovery genomics and a large number of novel disease-causing variants are being reported...
August 10, 2017: Strabismus
https://www.readbyqxmd.com/read/28792705/homocysteine-metabolism-and-hematological-parameters-in-early-stage-of-phenytoin-treated-epileptic-children
#3
Tarun K Sharma, S K Vardey, S Sitaraman
BACKGROUND: Long-term antiepileptic drug (AED) therapy has been associated with metabolic consequences that lead to an increase in risk of atherosclerosis in patients with epilepsy. Earlier published studies showed conflicting results about the levels of hematological parameters, serum homocysteine, folate, and vitamin B12, in epileptics treated with phenytoin monotherapy. Therefore, we evaluated homocysteine metabolism and hematological parameters in early stage of phenytoin treated epileptic children...
July 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28776919/open-surgical-mitral-valve-replacement-with-a-transcatheter-edwards-sapien-xt-valve
#4
Tanveer Ahmad, Prakash M Ludhani, Ronen Gurvitch, John Goldblatt, James Tatoulis
No abstract text is available yet for this article.
August 4, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28768675/percutaneous-valve-in-valve-in-the-tricuspid-position-in-a-patient-with-tetralogy-of-fallot
#5
Abhinay Challa, Ryan Markham, Darren Walters
Here, we describe a case of a successful percutaneous insertion of a transcatheter 29 mm Edwards Sapien XT valve into a tricuspid valve in a patient with repaired tetralogy of fallot.Similar procedures have been performed with the Edwards Sapien valve and Melody valves; however, this is the first case described in the literature of an Edwards Sapien valve used in a patient with Tetralogy of Fallot.With procedural safety being demonstrated, this case illustrates an important alternative treatment option for patients with congenital heart disease...
August 2, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28764288/evaluating-the-marginal-integrity-of-bulk-fill-fibre-reinforced-composites-in-bio-mimetically-restored-tooth
#6
Arun Kumar Patnana, V Narsimha Rao Vanga, Srinivas Kumar Chandrabhatla
INTRODUCTION: Over the past years, composites in aesthetic dentistry are showing a considerable progress, but mechanical strength and polymerization shrinkage are the two main drawbacks, which limit their use in high stress bearing areas. AIM: To evaluate the marginal integrity of short glass fibre reinforced composite restorations, fibre reinforced composites with composite superficial layer, and fibre reinforced composites with underlying flowable composite layer...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28761403/transcatheter-tricuspid-valve-in-valve-replacement-with-an-edwards-sapien-3-valve
#7
Pranav Loyalka, Angelo Nascimbene, Benjamin Metz, Igor D Gregoric, Ajay Sundara Raman, Biswajit Kar
A few case reports and case series have documented the outcomes in patients with tricuspid bioprosthetic valvular degeneration who underwent transcatheter implantation of the Medtronic Melody and the Edwards Sapien XT and Sapien 3 valves. In this report, we describe the case of a 49-year-old woman with severe bioprosthetic tricuspid valvular stenosis and multiple comorbidities who underwent transcatheter tricuspid valve replacement with a Sapien 3 valve.
June 2017: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/28760680/genetic-analysis-of-a-per-2-producing-shewanella-spp-strain-harboring-a-variety-of-mobile-genetic-elements-and-antibiotic-resistant-determinants
#8
Marisa Almuzara, Sabrina Montaña, Terese Lazzaro, Sylvia Uong, Gisela Parmeciano Di Noto, German Traglia, Romina Bakai, Daniela Centrón, Andrés Iriarte, Cecilia Quiroga, Maria Soledad Ramirez
OBJECTIVE: The goal of this work is to investigate the molecular mechanisms that explain the multidrug resistant phenotype found in a novel clinical Shewanella spp. strain (Shew256) recovered from a diabetic patient. METHODS: The whole-genome shotgun sequencing was obtained with Illumina MiSeq-I and Nextera XT DNA library. De novo assembly was performed with SPADES. RAST was used to predict the open reading frames and the predictions were confirmed using BLAST. Further genomic analysis was carried out using average nucleotide identity (ANI), ACT (Artemis), OrthoMCL, ARG-ANNOT, ISFinder, PHAST, tRNAscan-SE, plasmidSPAdes, PlasmidFinder and MAUVE...
July 28, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28760396/transcatheter-aortic-valve-replacement-with-new-generation-devices-a-systematic-review-and-meta-analysis
#9
Marco Barbanti, Sergio Buccheri, Josep Rodés-Cabau, Simona Gulino, Philippe Généreux, Gerlando Pilato, Danny Dvir, Andrea Picci, Giuliano Costa, Corrado Tamburino, Martin B Leon, John G Webb
OBJECTIVE: The aim of this study was to conduct a weighted meta-analysis to determine the rates of acute (≤30days) major outcomes after (TAVR) with second-generation devices. METHODS: A comprehensive search of multiple electronic databases from January 2011 to May 2017 was conducted using predefined criteria. New-generation TAVR devices were defined as any device which received CE mark approval or is still under evaluation for CE marking after CoreValve and SAPIEN XT prostheses...
July 25, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28757348/draft-genome-sequence-of-an-aminoglycoside-resistant-rmtd-2-producing-enterobacter-cloacae-subsp-cloacae-st-395-in-brazil
#10
Evelin Rodrigues Martins, Maria Fernanda Campagnari Bueno, Gabriela Rodrigues Francisco, Fernanda Modesto Tolentino, Louise Cerdeira, Tiago Casella, Monalisa Nogueira Costa, Carla Cevada, Nilton Lincopan, Doroti de Oliveira Garcia, Mara Corrêa Lelles Nogueira
OBJECTIVES: Enterobacter cloacae has recently emerged as an important agent of nosocomial infections, due to the diffusion of extended spectrum β-lactamases and carbapenemases in this species. In this context, a raise in the use of aminoglycosides for therapy was noticed, being followed by the accelerated development of resistance mechanisms. In this study, we report the draft genome sequence of a multidrug-resistant Enterobacter cloacae subsp. cloacae strain (Ec2), isolated from active surveillance culture of a patient with Chagas disease...
July 27, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28742057/effect-of-photodynamic-therapy-in-the-reduction-of-halitosis-in-patients-with-multiple-sclerosis-clinical-trial
#11
Marcela Leticia Leal Gonçalves, Sandra Kalil Bussadori, Yara Dadalti Fragoso, Vinícius Vieira Belarmino da Silva, Alessandro M Deana, Ana Carolina Ciarcia, Erika Horácio Pinto, Anna Carolina Ratto Tempestini Horliana, Cristiane Miranda França
Smell and odours play a vital role in social interaction. Halitosis is a social problem that affects one-third of the population causing a negative impact in the quality of life. There is little knowledge on the prevalence and management of halitosis in Multiple Sclerosis (MS) patients. The present study aimed to evaluate the presence of halitosis in patients with MS when compared to a control group and the treatment with antimicrobial photodynamic therapy (aPDT) against halitosis. This is a case-control clinical study where 60 patients were evaluated: 30 MS patients in treatment at the Specialties Clinic School of Medicine, and 30 healthy patients, matched in age and gender, for the control group...
July 25, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28737281/in-situ-evaluation-of-color-stability-and-hardness-decrease-of-resin-based-composites
#12
Juliana Silva Ribeiro, Sonia Luque Peralta, Vinícius Esteves Salgado, Rafael Guerra Lund
OBJECTIVE: To determine the color stability (CS) and hardness' decrease (HD) of two commercial resin-based composites (RBCs), after in situ staining conditions (SC). METHODS: Six disc-shaped specimens (6 × 2 mm) of two RBCs-Filtek Z350 XT (FZX) and IPS Empress Direct (IED)-were randomly distributed into palatal devices. Eight volunteers (aged 20-30 years) participated in this study. The in situ SC consisted of 400 mL consumption (2 × 200 mL/day) of water, orange juice, cola soda, and coffee and 140 mL consumption of red wine, 10 days each...
July 24, 2017: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/28727319/novel-evaluation-and-treatment-techniques-for-white-spot-lesions-an-in-vitro-study
#13
T A Bakhsh, A S Bakry, M M Mandurah, M A Abbassy
OBJECTIVE: White spot lesions (WSLs) are commonly seen during and after orthodontic treatment. Therefore, the objective of this in vitro study was to assess the effect of 45S5-bioglass in remineralizing WSLs using cross-polarization optical coherence tomography (CP-OCT) and confirm the findings by micro-hardness test. METHODS: Ceramic orthodontic brackets were bonded to the buccal surface of 45 human premolars with Transbond XT primer followed by Transbond PLUS according to the manufacturer's instructions...
August 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28694726/a-nationwide-multicentre-study-in-turkey-for-establishing-reference-intervals-of-haematological-parameters-with-novel-use-of-a-panel-of-whole-blood
#14
Yesim Ozarda, Kiyoshi Ichihara, Ebubekir Bakan, Harun Polat, Nurinnisa Ozturk, Nurcan K Baygutalp, Fatma Taneli, Yesim Guvenc, Murat Ormen, Zubeyde Erbayraktar, Nurten Aksoy, Hatice Sezen, Meltem Demir, Gulcin Eskandari, Gurbuz Polat, Nuriye Mete, Hatice Yuksel, Husamettin Vatansev, Fatma Gun, Okhan Akin, Ozlem Ceylan, Tevfik Noyan, Ozgul Gozlukaya, Yuksel Aliyazicioglu, Sevim Kahraman, Melahat Dirican, Gul Ozlem Tuncer, Shogo Kimura, Pinar Eker
INTRODUCTION: A nationwide multicentre study was conducted to establish well-defined reference intervals (RIs) of haematological parameters for the Turkish population in consideration of sources of variation in reference values (RVs). MATERIALS AND METHODS: K2-EDTA whole blood samples (total of 3363) were collected from 12 laboratories. Sera were also collected for measurements of iron, UIBC, TIBC, and ferritin for use in the latent abnormal values exclusion (LAVE) method...
June 15, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28691908/high-pressure-balloon-fracturing-of-small-dysfunctional-mitroflow-bioprostheses-facilitates-transcatheter-aortic-valve-in-valve-implantation
#15
Jens Erik Nielsen-Kudsk, Asger Andersen, Christian Juhl Therkelsen, Evald Høj Christensen, Kaare Troels Jensen, Lars Romer Krusell, Mariann Tang, Kim Allan Terp, Kaj-Erik Klaaborg, Jacob Raben Greisen, Bjarne Linde Nørgaard, Henning Rud Andersen
AIMS: Transcatheter valve-in-valve (VIV) implantation in small surgical tissue valves is challenged by the problem of residual stenosis. We report our first ten cases of fracturing small dysfunctional Mitroflow bioprostheses by high-pressure balloon dilatation to increase the internal diameter of the surgical valve before VIV (BF-VIV). METHODS AND RESULTS: BF-VIV was performed in 10 patients (mean age 84±4 years) with failing Mitroflow valves size 19 mm (n=3, threshold of fracture 15 atm) and 21 mm (n=7, threshold of fracture 13 atm)...
July 11, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28691468/bacterial-colonization-of-the-implant-abutment-interface-of-conical-connection-with-an-internal-octagon-an-in-vitro-study-using-real-time-pcr
#16
A Baj, G A Beltramini, A Bolzoni, F Cura, A Palmieri, A Scarano, L Ottria, A B Giannì
Bacterial leakage at the implant-abutment connection of a two-piece implant system is considered the main cause of peri-implantitis. Prevention of bacterial leakage at the implant-abutment connection is mandatory for reducing inflammation process around implant neck and achieving bone stability. Micro-cavities at implant-abutment connection level can favour bacterial leakage, even in modern two-piece implant systems. The conical connection with an internal octagon (CCIO) is considered to be more stable mechanically and allows a more tight link between implant and abutment...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28690463/in-vivo-plantar-pressures-in-adult-acquired-flatfoot-compared-to-control-using-an-intraoperative-pedobarographic-device
#17
Aoife MacMahon, Howard J Hillstrom, Huong T Do, Jeremy Y Chan, Jonathan T Deland, Scott J Ellis
BACKGROUND: Intraoperative pedobarography has the potential to aid surgical decisions, but no parameters exist to guide its use. QUESTIONS/PURPOSES: This study compared supine plantar pressures between flatfoot patients and controls using a previously validated intraoperative pedobarographic device and examined associations between supine, walking, and standing plantar pressures. METHODS: Ten preoperative patients with stage II adult-acquired flatfoot deformity (AAFD) were compared to ten healthy controls...
July 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28686499/pathologists-computer-assisted-diagnosis-a-mock-up-of-a-prototype-information-system-to-facilitate-automation-of-pathology-sign-out
#18
Navid Farahani, Zheng Liu, Dylan Jutt, Jeffrey L Fine
CONTEXT: - Pathologists' computer-assisted diagnosis (pCAD) is a proposed framework for alleviating challenges through the automation of their routine sign-out work. Currently hypothetical, pCAD is based on a triad of advanced image analysis, deep integration with heterogeneous information systems, and a concrete understanding of traditional pathology workflow. Prototyping is an established method for designing complex new computer systems such as pCAD. OBJECTIVE: - To describe, in detail, a prototype of pCAD for the sign-out of a breast cancer specimen...
July 7, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28683478/-emergency-keratoplasty-with-porcine-xenografts-in-necrotizing-keratitis
#19
Galyna I Drozhzhyna, Tetiana B Gaidamaka, Claus Cursiefen, Björn O Bachmann, Olena V Ivanovska, Viktor L Ostashevsky, Boris M Kogan, Volodymyr J Usov, Natalija V Pasyechnikova
Background The great shortage of donor material in Ukraine makes it necessary to find additional sources of transplant material. A possible suitable material are the porcine corneas, as they are similar in structure and biomechanical parameters to the human cornea. The purpose of our study was to analyze the results of therapeutic keratoplasty (KP) with keratoxenotransplants from cryolyophilized porcine corneas in patients with severe necrotizing keratitis. Methods A retrospective analysis of 32 xenotransplantations patients with severe necrotizing keratitis (17 lamellar, 6 stepped perforating, 4 perforating, 5 "biological coverage" according to Puchkovskaya) was completed...
July 6, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28682703/clinical-performance-of-different-solvent-based-dentin-adhesives-with-nanofill-or-nanohybrid-composites-in-class-iii-restorations-five-year-results
#20
M Demirci, S Tuncer, H S Sancaklı, N Tekçe, C Baydemir
PURPOSE: To evaluate the clinical performance of water, acetone, ethanol, and ethanol-water solvent-based dentin adhesives with nanofill or nanohybrid composites in Class III restorations. METHODS AND MATERIALS: A total of 22 patients aged between 14 and 48 years (mean age: 25.2 years) participated in the study. Each patient received four Class III restorations, which were performed using water (Scotchbond Multipurpose), acetone (Prime&Bond NT), ethanol (XP Bond) and ethanol-water (Xeno V) solvent-based dentin adhesive systems with a nanofill (Filtek Supreme XT) or nanohybrid composite (CeramX Duo)...
July 2017: Operative Dentistry
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