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https://www.readbyqxmd.com/read/28640778/a-cohort-study-of-blunt-cerebrovascular-injury-screening-in-children-are-they-just-little-adults
#1
Mackenzie R Cook, Cordelie E Witt, Robert H Bonow, Eileen M Bulger, Ken F Linnau, Saman Arbabi, Bryce R H Robinson, Joseph Cuschieri
BACKGROUND: Blunt cerebrovascular injuries (BCVI) are rare with nonspecific predictors, making optimal screening critical. Radiation concerns magnify these issues in children. The Eastern Association for the Surgery of Trauma (EAST) criteria, the Utah score (US) and the Denver criteria (DC) have been advocated for pediatric BCVI screening, though direct comparison is lacking. We hypothesized that current screening guidelines inaccurately identify pediatric BCVI. METHODS: This was a retrospective cohort study of pediatric trauma patients treated from 2005-2015 with radiographically confirmed BCVI...
June 20, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28635549/a-missed-primary-care-appointment-correlates-with-a-subsequent-emergency-department-visit-among-children-with-asthma
#2
Colleen Marie McGovern, Margaret Redmond, Kimberly Arcoleo, David R Stukus
OBJECTIVE: Since the Affordable Care Act's implementation, emergency department (ED) visits have increased. Poor asthma control increases the risk of acute exacerbations and preventable ED visits. The Centers for Medicare and Medicaid Services support the reduction of preventable ED visits to reduce healthcare spending. Implementation of interventions to avoid preventable ED visits has become a priority for many healthcare systems yet little data exist examining children's missed asthma management primary care (PC) appointments and subsequent ED visits...
March 2, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28626444/aging-with-cerebral-small-vessel-disease-and-dizziness-the-importance-of-undiagnosed-peripheral-vestibular-disorders
#3
Niccolò Cerchiai, Michelangelo Mancuso, Elena Navari, Nicola Giannini, Augusto Pietro Casani
Recent studies showed a link between cerebral small vessel white matter disease (SVD) and dizziness: patients whose dizziness cannot be explained by vestibular disease show severe SVD and gait abnormalities; however, little is still known about how SVD can cause this symptom. The primary aim of this study is to examine the possible underlying causes of dizziness in neurovascular patients; this is in order to assess whether treatable causes could be routinely disregarded. A secondary aim is to possibly define a central oculomotor pattern induced per se by SVD...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28621548/an-investigation-into-the-mammographic-appearances-of-missed-breast-cancers-when-recall-rates-are-reduced
#4
Norhashimah Mohd Norsuddin, Claudia Mello-Thoms, Warren Reed, Mary Rickard, Sarah Lewis
OBJECTIVES: This study investigated whether certain mammographic appearances of breast cancer are missed when radiologists read at lower recall rates. METHODS: Five radiologists read one identical test set of 200 mammographic (180 normal cases and 20 abnormal cases) three times and were requested to adhere to three different recall rate conditions: free recall, 15% and 10%. The radiologists were asked to mark the locations of suspicious lesions and provide a confidence rating for each decision...
June 16, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28614165/magnet-hospital-recognition-in-hospital-systems-over-time
#5
Karen B Lasater, Michael R Richards, Nikila B Dandapani, Lawton R Burns, Matthew D McHugh
BACKGROUND: Magnet hospitals are recognized for nursing excellence and high-value patient outcomes, yet little is known about which and when hospitals pursue Magnet recognition. Concurrently, hospital systems are becoming a more prominent feature of the U.S. health care landscape. PURPOSE: The aim of the study was to examine Magnet adoption among hospital systems over time. APPROACH: Using American Hospital Association surveys (1998-2012), we characterized the proportion of Magnet hospitals belonging to systems...
June 13, 2017: Health Care Management Review
https://www.readbyqxmd.com/read/28609794/-destruction-of-microsurgical-devices-by-sterilisation
#6
Raphaela Berto, Jürgen Strutz
Hospital facilities issue numerous risk announcements on corrosion, deformation or premature wearout of medical devices every year. As there is yet little data on the impact of reprocessing on the quality and durability of microsurgical instruments, this paper aims at evaluating the effects of the reprocessing on microsurgical instruments. Material and Methods 22 brand new microsurgical instruments for stapes surgery were being reprocessed 30 times without being used for surgery or other purposes in the interim time...
June 13, 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28604028/re-reading-after-mind-wandering
#7
Trish L Varao-Sousa, Grayden J F Solman, Alan Kingstone
Though much research has been conducted on the causes and processes underlying mind wandering, relatively little has addressed what happens after an episode of mind wandering. We explore this issue in the context of reading. Specifically, by examining re-reading behaviours following mind wandering episodes. Results from 2 studies reveal that after mind wandering, participants re-read nearly half the time. This re-reading occurs whether mind wandering is self-caught or probe-caught, and it typically involves retracing a line or 2 of text...
June 12, 2017: Canadian Journal of Experimental Psychology, Revue Canadienne de Psychologie Expérimentale
https://www.readbyqxmd.com/read/28603337/sample-size-calculations-for-time-averaged-difference-of-longitudinal-binary-outcomes
#8
Ying Lou, Jing Cao, Song Zhang, Chul Ahn
In clinical trials with repeated measurements, the responses from each subject are measured multiple times during the study period. Two approaches have been widely used to assess the treatment effect, one that compares the rate of change between two groups and the other that tests the time-averaged difference (TAD). While sample size calculations based on comparing the rate of change between two groups have been reported by many investigators, the literature has paid relatively little attention to the sample size estimation for time-averaged difference (TAD) in the presence of heterogeneous correlation structure and missing data in repeated measurement studies...
2017: Communications in Statistics: Theory and Methods
https://www.readbyqxmd.com/read/28600900/screening-of-duplicated-loci-reveals-hidden-divergence-patterns-in-a-complex-salmonid-genome
#9
Morten T Limborg, Wesley A Larson, Lisa W Seeb, James E Seeb
A whole genome duplication (WGD) doubles the entire genomic content of a species and is thought to have catalyzed adaptive radiation in some polyploid-origin lineages. However, little is known about general consequences of a WGD since gene duplicates (i.e. paralogs) are commonly filtered in genomic studies; such filtering may remove substantial portions of the genome in data sets from polyploid-origin species. We demonstrate a new method that enables genome-wide scans for signatures of selection at both non-duplicated and duplicated loci by taking locus-specific copy number into account...
June 10, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28599749/statin-prescribing-for-prevention-of-cardiovascular-disease-amongst-people-with-severe-mental-illness-cohort-study-in-uk-primary-care
#10
R Blackburn, D Osborn, K Walters, I Nazareth, I Petersen
BACKGROUND: Severe mental illness (SMI) is associated with excess cardiovascular disease (CVD) morbidity, but little is known on provision of preventative interventions. We investigated statin initiation for primary CVD prevention in individuals with and without SMI. METHODS: We used primary care data from The Health Improvement Network from 2006 to 2015 for UK patients aged 30-99years with no pre-existing CVD conditions and selected individuals with schizophrenia (n=13,252) or bipolar disorder (n=11,994)...
June 6, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28599196/understanding-and-addressing-missed-care-in-clinical-placements-implications-for-nursing-students-and-nurse-educators
#11
Annamaria Bagnasco, Fiona Timmins, Jan M A de Vries, Giuseppe Aleo, Milko Zanini, Gianluca Catania, Loredana Sasso
This paper addresses the issue of substandard care and its effects on healthcare practice. It explores some recent concerns about the problem in nursing, its potential effects on students, how it can be conceptualised and what action needs to be, by both nurses and educators to prevent it. Recent healthcare scandals have tarnished the public image of nursing, and are also likely to influence nursing students' images, expectations and experiences of nursing. While much attention has been paid to the examination of such lapses in care, and potential corrective actions, little attention has been paid to the potential or actual effect on nursing students in practice...
May 23, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28594483/effect-of-an-institutional-medication-adherence-program-for-long-acting-injectable-risperidone-on-adherence-and-psychiatric-hospitalizations-evidence-from-a-prospective-cohort-study
#12
Jessica J Jalbert, Michel Rossignol, Bernard Astruc, Franck Baylé, Clementine Nordon, Bernard Avouac, Frédéric Rouillon, Lucien Abenhaim, Lamiae Grimaldi-Bensouda
BACKGROUND: Long-acting injectable (LAI) atypical antipsychotics are associated with improved adherence and reduced relapse rates in schizophrenia but reminder-based interventions may further improve outcomes. OBJECTIVES: To assess an institutional medication adherence program's (IMAP) effectiveness on adherence and psychiatric hospitalizations among schizophrenia patients taking risperidone LAI (RLAI). METHODS: Between 2009 and 2010, we recruited patients meeting DSM-IV criteria for schizophrenia treated with RLAI receiving outpatient care from psychiatric centres in France...
May 30, 2017: Journal of Population Therapeutics and Clinical Pharmacology
https://www.readbyqxmd.com/read/28594442/body-mass-index-and-risk-of-gastric-cancer-a-30-year-follow-up-study-in-the-linxian-general-population-trial-cohort
#13
Jin-Hu Fan, Jian-Bing Wang, Shao-Ming Wang, Christian C Abnet, You-Lin Qiao, Philip R Taylor
Although a number of previous studies have noted either positive or no association for body mass index (BMI) and gastric cancers risk, little evidence exists in the Chinese population. We prospectively examined the associations of BMI with risk of gastric cancers in the Linxian General Population Trial cohort, with 29,584 healthy adults enrolled in 1985 and followed through the end of 2014. Body weight and height were measured during physical examination at baseline and BMI was calculated as weight in kilograms divided by height in meters squared...
June 8, 2017: Cancer Science
https://www.readbyqxmd.com/read/28586149/comparative-analysis-of-von-willebrand-factor-profiles-after-implantation-of-left-ventricular-assist-device-and-total-artificial-heart
#14
H J Reich, J Morgan, F Arabia, L Czer, J Moriguchi, D Ramzy, F Esmailian, L Lam, J Dunhill, O Volod
BACKGROUND: Bleeding remains a challenge during mechanical circulatory support and underlying mechanisms are incompletely understood. Functional von Willebrand Factor (VWF) impairment due to loss of high molecular weight multimers (MWM) produces acquired von Willebrand Disease (VWD) after left ventricular assist device (LVAD). Little is known about VWF multimers with total artificial hearts (TAHs). Here, VWF profiles with LVADs and TAHs are compared using a VWD panel. METHODS: VWD evaluations for patients with LVAD or TAH (2013-14) were retrospectively analyzed and included: VWF activity (Ristocetin Cofactor, VWF:RCo), VWF antigen (VWF:Ag), ratio of VWF:RCo to VWF:Ag, and quantitative VWF multimeric analysis...
June 6, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28577424/specific-needs-of-families-of-young-adults-with-profound-intellectual-disability-during-and-after-transition-to-adulthood-what-are-we-missing
#15
Camille Gauthier-Boudreault, Frances Gallagher, Mélanie Couture
INTRODUCTION: At the age of 21, the trajectory of services offered to youth with profound intellectual disability (ID) change significantly since access to specialised services is more limited. Despite the desire of parents to avoid any impact on their child, several factors can influence the course of this transition. However, there is little research on facilitators and obstacles to the transition to adulthood, and impacts on people with a profound ID. It is therefore difficult to provide solutions that meet their specific needs...
May 31, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28577219/spo0m-structure-and-function-beyond-regulation-of-sporulation
#16
REVIEW
Luz Adriana Vega-Cabrera, Christopher D Wood, Liliana Pardo-López
In this mini-review, we present a perspective on the recent findings relating Spo0M structure and function that will stimulate and guide further studies in the characterization of this interesting protein. Cell division and sporulation constitute two of the best studied processes in the model organism Bacillus subtilis; however, there are many missing pieces in the giant regulatory puzzle that governs the independent and shared networks between them. Spo0M is a little studied protein that has been related to both, cell division and sporulation, but its biochemical function and its direct interactions have not been yet defined...
June 2, 2017: Current Genetics
https://www.readbyqxmd.com/read/28571913/multidisciplinary-design-and-analytic-approaches-to-advance-prospective-research-on-the-multilevel-determinants-of-child-health
#17
Sara B Johnson, Todd D Little, Katherine Masyn, Paras D Mehta, Sharon R Ghazarian
PURPOSE: Characterizing the determinants of child health and development over time, and identifying the mechanisms by which these determinants operate, is a research priority. The growth of precision medicine has increased awareness and refinement of conceptual frameworks, data management systems, and analytic methods for multilevel data. This article reviews key methodological challenges in cohort studies designed to investigate multilevel influences on child health and strategies to address them...
May 15, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/28567552/periodontitis-deteriorates-peripheral-arterial-disease-in-japanese-population-via-enhanced-systemic-inflammation
#18
Norio Aoyama, Jun-Ichi Suzuki, Naho Kobayashi, Tomoya Hanatani, Norihiko Ashigaki, Asuka Yoshida, Yuka Shiheido, Hiroki Sato, Hidetoshi Kumagai, Yuichi Ikeda, Hiroshi Akazawa, Issei Komuro, Yuichi Izumi, Mitsuaki Isobe
Peripheral arterial disease (PAD) is a common manifestation of arterial stenosis of the extremity that reduces arterial flow. While patients with periodontitis are at a high risk of PAD, little causal information has been provided to date. To clarify the relationship, we conducted this cross-sectional study. The oral condition of patients with or without PAD, who attended Tokyo Medical and Dental University Hospital, was evaluated. Blood examinations and dental clinical measurements, including number of teeth, probing pocket depth (PPD), bleeding on probing (BOP) and clinical attachment level (CAL) were performed...
May 31, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28560767/reviewing-the-quality-of-discourse-information-measures-in-aphasia
#19
REVIEW
Madeleine Pritchard, Katerina Hilari, Naomi Cocks, Lucy Dipper
BACKGROUND: Discourse is fundamental to everyday communication, and is an increasing focus of clinical assessment, intervention and research. Aphasia can affect the information a speaker communicates in discourse. Little is known about the psychometrics of the tools for measuring information in discourse, which means it is unclear whether these measures are of sufficient quality to be used as clinical outcome measures or diagnostic tools. AIMS: To profile the measures used to describe information in aphasic discourse, and to assess the quality of these measures against standard psychometric criteria...
May 31, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28560765/an-amazonian-rainforest-and-its-fragments-as-a-laboratory-of-global-change
#20
William F Laurance, José L C Camargo, Philip M Fearnside, Thomas E Lovejoy, G Bruce Williamson, Rita C G Mesquita, Christoph F J Meyer, Paulo E D Bobrowiec, Susan G W Laurance
We synthesize findings from one of the world's largest and longest-running experimental investigations, the Biological Dynamics of Forest Fragments Project (BDFFP). Spanning an area of ∼1000 km(2) in central Amazonia, the BDFFP was initially designed to evaluate the effects of fragment area on rainforest biodiversity and ecological processes. However, over its 38-year history to date the project has far transcended its original mission, and now focuses more broadly on landscape dynamics, forest regeneration, regional- and global-change phenomena, and their potential interactions and implications for Amazonian forest conservation...
May 30, 2017: Biological Reviews of the Cambridge Philosophical Society
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