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https://www.readbyqxmd.com/read/29686701/nontyphoidal-salmonella-gastroenteritis-in-a-tertiary-children-s-hospital-in-southern-china-characteristics-and-dietary-considerations
#1
Lu Ren, Min Yang, Lanlan Geng, Peiyu Chen, Huan Chen, Sitang Gong, Ding-You Li
Background: Nontyphoidal Salmonella infection is a common cause for acute bacterial gastroenteritis in children in China. There have been no reports of the prevalence of lactose intolerance or food allergies in children with nontyphoidal Salmonella infection. The aim of this study was to characterize nontyphoidal Salmonella gastroenteritis in a tertiary children's hospital and evaluate clinical presentation, lactose intolerance, and food allergies in children with prolonged nontyphoidal Salmonella gastroenteritis...
2018: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29674796/prescriber-and-dispenser-perceptions-about-antibiotic-use-in-acute-uncomplicated-childhood-diarrhea-and-upper-respiratory-tract-infection-in-new-delhi-qualitative-study
#2
Anita Kotwani, P C Joshi, Urmila Jhamb, Kathleen Holloway
OBJECTIVE: The objective of the study was to explore the prescribing practices, knowledge, and attitudes of primary care doctors and community pharmacists, regarding antibiotic use in acute upper respiratory tract infections (URTI) and diarrhea in children to better understand causes of misuse and identify provider suggestions to change such behavior. MATERIALS AND METHODS: Two focus group discussions (FGDs) each were conducted with primary care government doctors (GDs), private general practitioners (GPs), pediatricians, and community pharmacists in Delhi...
November 2017: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/29670776/-kit-d816v-positive-acute-mast-cell-leukemia-associated-with-normal-karyotype-acute-myeloid-leukemia
#3
Marta Lopes, Maria Dos Anjos Teixeira, Cláudia Casais, Vanessa Mesquita, Patrícia Seabra, Renata Cabral, José Palla-García, Catarina Lau, João Rodrigues, Maria Jara-Acevedo, Inês Freitas, Jose Ramón Vizcaíno, Jorge Coutinho, Luis Escribano, Alberto Orfao, Margarida Lima
Introduction: Mast cell (MC) leukemia (MCL) is extremely rare. We present a case of MCL diagnosed concomitantly with acute myeloblastic leukemia (AML). Case Report: A 41-year-old woman presented with asthenia, anorexia, fever, epigastralgia, and diarrhea. She had a maculopapular skin rash, hepatosplenomegaly, retroperitoneal adenopathies, pancytopenia, 6% blast cells (BC) and 20% MC in the peripheral blood, elevated lactate dehydrogenase, cholestasis, hypoalbuminemia, hypogammaglobulinemia, and increased serum tryptase (184  μ g/L)...
2018: Case Reports in Hematology
https://www.readbyqxmd.com/read/29661877/therapeutic-efficacy-of-bumped-kinase-inhibitor-1369-in-the-acute-pig-model-of-cryptosporidium-hominis
#4
Sangun Lee, Melanie Ginese, Gillian Beamer, Hillary R Danz, Donald J Girouard, Susan P Chapman-Bonofiglio, Minhee Lee, Matthew A Hulverson, Ryan Choi, Grant R Whitman, Kayode K Ojo, Samuel L M Arnold, Wesley C Van Voorhis, Saul Tzipori
Recent reports highlighting the global significance of cryptosporidiosis among children have renewed efforts to develop control measures. We evaluated the efficacy of bumped kinase inhibitor (BKI) 1369 in the gnotobiotic piglet model of acute diarrhea caused by Cryptosporidium hominis , the species responsible for most human cases. Five day-treatment with BKI 1369 reduced signs of disease early during treatment compared with untreated animals. Piglets treated with BKI 1369 exhibited a significant reduction of oocyst excretion, mucosal colonization by C...
April 16, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29657730/lemierre-s-syndrome-presented-with-acute-pancreatitis
#5
Laura Garcia, Kaori Ito
Case: Lemierre's syndrome is a rare clinical condition that is characterized by infected internal jugular vein thrombosis with metastatic septicemia. The most common causative agent is Fusobacterium necrophorum . A previously healthy 37-year-old woman presented to our emergency department with nausea, vomiting, and diarrhea. She was admitted to the general practice unit with a diagnosis of acute pancreatitis then was subsequently transferred to the intensive care unit due to shock. Physical examination revealed tenderness on right side of the neck...
April 2018: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29657713/mid-upper-arm-circumference-based-case-detection-admission-and-discharging-of-under-five-children-in-a-large-scale-community-based-management-of-acute-malnutrition-program-in-nigeria
#6
Stanley Chitekwe, Sibhatu Biadgilign, Assaye Tolla, Mark Myatt
Background: Severe acute malnutrition (SAM) threatens the lives of millions of children worldwide particularly in low and middle-income countries (LMICs). Community-based management of acute malnutrition (CMAM) is an approach to treating large numbers of cases of severe acute malnutrition (SAM) in a community setting. There is a debate about the use of mid-upper arm circumference (MUAC) for admitting and discharging SAM children. This article describes the experience of using MUAC for screening, case-finding, referral, admission, and discharge in a large-scale CMAM program delivered through existing primary health care facilities in Nigeria...
2018: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/29655631/detection-of-rotavirus-before-and-after-monovalent-rotavirus-vaccine-introduction-and-vaccine-effectiveness-among-children-in-mainland-tanzania
#7
Bhavin Jani, Adolfine Hokororo, Jackson Mchomvu, Margaret M Cortese, Christopher Kamugisha, Delphinius Mujuni, Dotto Kallovya, Umesh D Parashar, Jason M Mwenda, DaFrossa Lyimo, Antonia Materu, Kakuri Frank Omari, Mark Waziri, Theresia Laswai, Hamisi Juma, Josephine Mlay, Juliana Dogani, Eugenia Stephen, Mwanisha Seugendo, Uyanjo Nkumbi, Anna Lyakurwa, Anivera Matojo, Elice Bendera, Jonathan Senyota, Veronica Msingwa, Yohana Fungo, Fausta Michael, Amina Mpamba, Alfred Chambo, Happy Cholobi, Faraja Lyamuya, Inviollatha Chami, Esther Mchome, Amina Mohamed Mshana, Edward Mushi, Uforo Mariki, Ronica Chard, Deborah Tuju, Nuswe Ambokile, Fatuma Lukwale, Furaha Kyessi, Asha Khamis, Innocent Michael, Doreen Macha, Angelina Saguti
BACKGROUND: Monovalent rotavirus vaccine (RV1) was introduced in Tanzania in January 2013 under the Reach Every Child initiative, to be given at ages 6 and 10 weeks. We used the sentinel hospital rotavirus surveillance system to examine the rotavirus detection rate before and after vaccine introduction and estimate vaccine effectiveness. METHODS: Before vaccine introduction, rotavirus surveillance was established at two mainland hospitals; children admitted for acute diarrhea were eligible for enrollment and stools were tested for rotavirus antigen...
April 11, 2018: Vaccine
https://www.readbyqxmd.com/read/29650387/tpf-induction-chemotherapy-followed-by-concurrent-chemoradiotherapy-for-locally-advanced-nasopharyngeal-carcinoma-long-term-results-of-a-tunisian-series
#8
N Toumi, W Ben Kridis, W Mnejja, R Bouzguenda, A Khanfir, A Ghorbel, J Daoud, M Frikha
PURPOSE: We represent in this study the long term results of docetaxel, cisplatin and 5-fluorouracil induction chemotherapy followed by concurrent chemoradiotherapy in Tunisian patients with locally advanced nasopharyngeal carcinoma. The objective of our study is to analyse the efficacy as well as the toxicity of this therapeutic protocol. PATIENTS AND METHODS: Between January 2004 and December 2008, 32 patients with locoregional advanced non metastatic disease (T2b or above and/or N1 or above AJCC 2002) were treated in our institution by three cycles of docetaxel, cisplatin and 5-fluorouracil induction chemotherapy every 21 days followed by concurrent chemoradiotherapy...
April 9, 2018: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/29649189/acute-metam-sodium-poisoning-caused-by-occupational-exposure-at-a-flower-farm-uganda-october-2016
#9
Susan Nakubulwa, Joy Kusiima, Daniel Kadobera, Joan N Mutyoba, Alex R Ario, Bao-Ping Zhu
On October 25, 2016, media reports alerted the Uganda Ministry of Health to an outbreak of >80 cases of vomiting, syncope, and acute diarrhea among workers at a flower farm in central Uganda; 27 workers were hospitalized. On November 1, an investigation was undertaken by the Uganda Public Health Fellowship Program.* A case-control study found that working inside greenhouse 7, which had been fumigated with the organosulfur compound metam sodium the night of October 13, was strongly associated with illness...
April 13, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29628968/clinical-manifestation-of-campylobacter-enteritis-in-children
#10
Joon Yeol Bae, Dong Hyuk Lee, Kyung Ok Ko, Jae Woo Lim, Eun Jeong Cheon, Young Hwa Song, Jung Min Yoon
Purpose: Timely antibiotic therapy in selected cases of diarrhea associated with bacterial infections can reduce the duration and severity of illness and prevent complications. The availability of a predictive index before identification of causative bacteria would aid in the choice of a therapeutic agent. Methods: The study included patients admitted to the pediatrics unit at Konyang University Hospital for acute inflammatory diarrhea from August 1, 2015 to July 31, 2016 who underwent multiplex polymerase chain reaction testing...
March 2018: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/29627242/exopolysaccharide-from-lactobacillus-plantarum-lrcc5310-offers-protection-against-rotavirus-induced-diarrhea-and-regulates-inflammatory-response
#11
Kiyoung Kim, Gyeonghweon Lee, Hien Dang Thanh, Jong-Hwa Kim, Maytiya Konkit, Seokmin Yoon, Miri Park, Siyoung Yang, Eunsup Park, Wonyong Kim
We aimed to determine the effects of Lactobacillus strains against rotaviral infections. Rotaviruses are the major causative agent of acute gastroenteritis in infants and children worldwide. However, to date, no specific antiviral drugs for the treatment of rotavirus infection have been developed. We identified 263 Lactobacillus strains from 35 samples of the traditional Korean fermented vegetable food, kimchi. Among them, Lactobacillus plantarum LRCC5310, more specifically the exopolysaccharides produced by these cells, were shown to have an antiviral effect against human rotavirus Wa strain in vitro...
April 4, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29625176/high-doses-of-antisecretory-factor-stop-diarrhea-fast-without-recurrence-for-six-weeks-post-treatment
#12
Shakila Zaman, Khalida Aamir, Lars Å Hanson, Stefan Lange
BACKGROUND: Diarrheal illnesses in young children cause morbidity and preventable deaths in developing countries. We evaluated two high doses of Salovum® [Antisecretory Factor] to treat diarrhea in young children and followed for recurrence 6 weeks post treatment. METHODS: Forty children, 6-24 months old, admitted with acute diarrhea, to the Outpatient Department of Children's Hospital in Lahore, Pakistan were selected. The patients were randomly allocated to either Group A given 2 sachets, or to Group B, given 4 sachets...
April 3, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29624592/anti-o-specific-polysaccharide-osp-immune-responses-following-vaccination-with-oral-cholera-vaccine-cvd-103-hgr-correlate-with-protection-against-cholera-after-infection-with-wild-type-vibrio-cholerae-o1-el-tor-inaba-in-north-american-volunteers
#13
Kamrul Islam, Motaher Hossain, Meagan Kelly, Leslie M Mayo Smith, Richelle C Charles, Taufiqur Rahman Bhuiyan, Pavol Kováč, Peng Xu, Regina C LaRocque, Stephen B Calderwood, Jakub K Simon, Wilbur H Chen, Douglas Haney, Michael Lock, Caroline E Lyon, Beth D Kirkpatrick, Mitchell Cohen, Myron M Levine, Marc Gurwith, Jason B Harris, Firdausi Qadri, Edward T Ryan
BACKGROUND: Cholera is an acute voluminous dehydrating diarrheal disease caused by toxigenic strains of Vibrio cholerae O1 and occasionally O139. A growing body of evidence indicates that immune responses targeting the O-specific polysaccharide (OSP) of V. cholerae are involved in mediating protection against cholera. We therefore assessed whether antibody responses against OSP occur after vaccination with live attenuated oral cholera vaccine CVD 103-HgR, and whether such responses correlate with protection against cholera...
April 6, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29621942/intestinal-lesions-in-dogs-with-acute-hemorrhagic-diarrhea-syndrome-associated-with-netf-positive-clostridium-perfringens-type-a
#14
Miriam Leipig-Rudolph, Kathrin Busch, John F Prescott, Iman Mehdizadeh Gohari, Christian M Leutenegger, Walter Hermanns, Georg Wolf, Katrin Hartmann, Jutta Verspohl, Stefan Unterer
Acute hemorrhagic diarrhea syndrome (AHDS), formerly named canine hemorrhagic gastroenteritis, is one of the most common causes of acute hemorrhagic diarrhea in dogs, and is characterized by acute onset of diarrhea, vomiting, and hemoconcentration. To date, histologic examinations have been limited to postmortem specimens of only a few dogs with AHDS. Thus, the aim of our study was to describe in detail the distribution, character, and grade of microscopic lesions, and to investigate the etiology of AHDS. Our study comprised 10 dogs with AHDS and 9 control dogs of various breeds, age, and sex...
April 1, 2018: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29619212/validity-of-maternal-report-of-care-seeking-for-childhood-illness
#15
Emily D Carter, Micky Ndhlovu, Melinda Munos, Emmy Nkhama, Joanne Katz, Thomas P Eisele
Background: Accurate data on care-seeking for child illness are needed to improve public health programs and reduce child mortality. The accuracy of maternal report of care-seeking for child illness as collected through household surveys has not been validated. Methods: A 2016 survey compared reported care-seeking against a gold-standard of health care provider documented care-seeking events among a random sample of mothers of children <5 years in Southern Province, Zambia...
June 2018: Journal of Global Health
https://www.readbyqxmd.com/read/29617871/clinical-and-laboratory-predictors-of-shiga-toxin-producing-escherichia-coli-infection-in-children-with-bloody-diarrhea
#16
Ryan S McKee, Phillip I Tarr, Dennis J Dietzen, Rachit Chawla, David Schnadower
Objectives: Children with acute bloody diarrhea are at risk of being infected with Shiga toxin-producing Escherichia coli (STEC) and of progression to hemolytic uremic syndrome. Our objective was to identify clinical and laboratory factors associated with STEC infection in children who present with acute bloody diarrhea. Methods: We performed a prospective cohort study of consecutive children younger than 18 years who presented with acute (<2-week duration) bloody diarrhea between August 1, 2013, and August 1, 2014...
April 2, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29615247/evaluation-of-bovine-viral-diarrhea-virus-transmission-potential-to-na%C3%A3-ve-calves-by-direct-and-indirect-exposure-routes
#17
Shollie M Falkenberg, Rohana P Dassanayake, John D Neill, Julia F Ridpath
Bovine viral diarrhea viruses (BVDV) can cause both acute and persistent infections in cattle. Exposure to BVDV persistently infected (PI) animals results in transmission of the virus to a naïve animal which causes a transient acute infection. While it is known that direct exposure to PI animals is a highly efficient means of transmission, less information is available regarding the potential for transmission from acutely infected either by direct or indirect exposure to naïve animals. Therefore, the objective of this study was to evaluate the potential for spread of the virus from calves acutely infected, with typical virulence field viruses know to have minimal shedding and viremia, to naïve contact animals either by direct or indirect exposure...
April 2018: Veterinary Microbiology
https://www.readbyqxmd.com/read/29614995/racecadotril-in-the-treatment-of-acute-diarrhea-in-children-a-systematic-comprehensive-review-and-meta-analysis-of-randomized-controlled-trials
#18
Marion Eberlin, Min Chen, Tobias Mueck, Jan Däbritz
BACKGROUND: Racecadotril is a guideline-recommended option for the treatment of acute diarrhea in children but existing guidelines and previous reviews of the field are based on a small fraction of published evidence. Therefore, we have performed a systematic search for randomized controlled trials evaluating racecadotril as add-on or in comparison to other treatments. METHODS: A search was performed in PubMed, Scopus and Google Scholar without limits about country of origin or reporting language...
April 3, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29614595/-the-462nd-case-chronic-watery-diarrhea-and-acute-kidney-injury
#19
Y H Ni, J Li, W X Zhou, Y P Luo, Q W Jiang, Y Liu, C Yue, G Sun, J M Qian
A 60-year-old man presented with severe watery diarrhea for 2 months complicated with weight loss and acute kidney injury. He did not respond well to antidiarrheal medicines, empirical antibiotics and dietary exclusion of gluten or even complete bowel rest. The final diagnosis of autoimmune enteropathy (AIE) was made based on histopathologic findings of endoscopic biopsy from duodenal mucosa after excluding neoplastic disease, inflammatory bowel disease, and infectious diarrhea, etc. Chronic diarrhea and oliguria alleviated after the administration of corticosteroids...
April 1, 2018: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29614051/the-effect-of-seasonal-floods-on-health-analysis-of-six-years-of-national-health-data-and-flood-maps
#20
Dell D Saulnier, Claudia Hanson, Por Ir, Helle Mölsted Alvesson, Johan von Schreeb
There is limited knowledge on the effect of seasonal flooding on health over time. We quantified the short- and long-term effects of floods on selected health indicators at public healthcare facilities in 11 districts in Cambodia, a flood-prone setting. Counts of inpatient discharge diagnoses and outpatient consultations for diarrhea, acute respiratory infections, skin infections, injuries, noncommunicable diseases and vector-borne diseases were retrieved from public healthcare facilities for each month between January 2008 and December 2013...
April 3, 2018: International Journal of Environmental Research and Public Health
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