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compressive cervical spondylotic myelopathy

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https://www.readbyqxmd.com/read/28711563/application-of-neurite-orientation-dispersion-and-density-imaging-or-diffusion-tensor-imaging-to-quantify-the-severity-of-cervical-spondylotic-myelopathy-and-assess-postoperative-neurological-recovery
#1
Genki Okita, Tetsuro Ohba, Tomohiro Takamura, Shigeto Ebata, Ryo Ueda, Hiroshi Onishi, Hirotaka Haro, Masaaki Hori
BACKGROUND CONTEXT: Surgical outcome and the severity of cervical spondylotic myelopathy (CSM) are unpredictable and cannot be estimated by conventional anatomical MRI. The utility of diffusion tensor imaging (DTI) to quantify the severity of CSM and assess postoperative neurological recovery has been investigated. However, whether conventional DTI should be applied in a clinical setting remains controversial. Neurite orientation dispersion and density imaging (NODDI) is a recently introduced model-based diffusion-weighted MRI technique that quantifies specific microstructural features related directly to neuronal morphology...
July 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28701500/assessing-structure-and-function-of-myelin-in-cervical-spondylotic-myelopathy-evidence-of-demyelination
#2
Hanwen Liu, Erin L MacMillian, Catherine R Jutzeler, Emil Ljungberg, Alex L MacKay, Shannon H Kolind, Burkhard Mädler, David K B Li, Marcel F Dvorak, Armin Curt, Cornelia Laule, John L K Kramer
PURPOSE: To assess the extent of demyelination in cervical spondylotic myelopathy (CSM) using myelin water imaging (MWI) and electrophysiologic techniques. METHODS: Somatosensory evoked potentials (SSEPs) and MWI were acquired in 14 patients with CSM and 18 age-matched healthy controls. MWI was performed on a 3.0T whole body magnetic resonance scanner. Myelin water fraction (MWF) was extracted for the dorsal columns and whole cord. SSEPs and MWF were also compared with conventional MRI outcomes, including T2 signal intensity, compression ratio, maximum spinal cord compression (MSCC), and maximum canal compromise (MCC)...
July 12, 2017: Neurology
https://www.readbyqxmd.com/read/28676461/cervical-burst-fracture-in-a-patient-with-contiguous-two-level-cervical-stand-alone-cages-a-case-report
#3
Rui Feng, Joshua Loewenstern, John Caridi
BACKGROUND: Cervical stand-alone interbody cages have seen increasingly wider use over the plate-and-screw construct in single-level anterior cervical discectomy and fusion (ACDF) in the treatment of cervical disc herniation and degenerative spondylotic conditions. Despite positive clinical outcomes, the efficacy and safety of using these devices in contiguous multi-level ACDF, however, has remained controversial. CASE DESCRIPTION: This report discusses a burst fracture seen as a complication in multi-level cervical stand-alone cage use...
July 1, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28591038/indication-for-hypertrophy-posterior-longitudinal-ligament-removal-in-anterior-decompression-for-cervical-spondylotic-myelopathy
#4
Chengrui Bai, Kanghua Li, Ai Guo, Qi Fei, Dong Li, Jinjun Li, Bingqiang Wang, Yong Yang
The retrospective study aimed to investigate the indication for hypertrophy posterior longitudinal ligament (HPLL) removal in anterior decompression for cervical spondylotic myelopathy (CSM). A total of 138 consecutive patients with CSM were divided into 2 groups with developmental cervical stenosis (DCS) (group S) and non-DCS (group N), according to the Pavlov ratio. These 2 groups were subdivided into 2 further subgroups, according to whether HPLL was removed or preserved: group SR (49 patients) and group SP (32 patients) in group S, group NR (21 patients) and group NP (36 patients) in group N...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28462691/neurodegeneration-in-the-spinal-ventral-horn-prior-to-motor-impairment-in-cervical-spondylotic-myelopathy
#5
Patrick Grabher, Siawoosh Mohammadi, Gergely David, Patrick Freund
Remote gray matter pathology has been suggested rostral to the compression site in cervical spondylotic myelopathy (CSM). We therefore assessed neurodegeneration in the gray matter ventral and dorsal horns. Twenty patients with CSM and 18 healthy subjects underwent a high-resolution structural and diffusion magnetic resonance imaging protocol at vertebra C2/C3. Patients received comprehensive clinical assessments. T2*-weighted data provided cross-sectional area measurements of gray matter ventral and dorsal horns to identify atrophy...
August 1, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28402031/evaluation-of-osseous-associated-cervical-spondylomyelopathy-in-dogs-using-kinematic-magnetic-resonance-imaging
#6
Michele Provencher, Amy Habing, Sarah A Moore, Laurie Cook, Gary Phillips, Ronaldo C da Costa
Osseous-associated cervical spondylomyelopathy in dogs is characterized by both static and dynamic spinal cord compression; however, standard MRI methods only assess static compression. In humans with cervical spondylotic myelopathy, kinematic MRI is commonly used to diagnose dynamic spinal cord compressions. The purpose of this prospective, analytical study was to evaluate kinematic MRI as a method for characterizing the dynamic component of osseous-associated cervical spondylomyelopathy in dogs. We hypothesized that kinematic MRI would allow visualization of spinal cord compressions that were not identified with standard imaging...
April 12, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28394776/correlation-analysis-between-modic-change-of-cervical-vertebrae-and-intramedullary-high-signal-intensity
#7
Hao Zhou, Jin Fan, Peng Sun, Wei Zhou, Qingqing Li, Lipeng Yu, Guoyong Yin
PURPOSE: Clinical studies have shown that endplate Modic change in the cervical spine and intramedullary high signal intensity often occurs simultaneously. We aimed to investigate whether there is a correlation between Modic change and intramedullary high signal intensity, and to explore the possible risk factors. MATERIALS AND METHODS: In total, 133 patients with cervical spondylotic myelopathy treated at the First Affiliated Hospital of Nanjing Medical University between May 2009 and March 2013 were enrolled in the study...
April 7, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28328846/prevalence-of-complications-after-surgery-in-treatment-for-cervical-compressive-myelopathy-a-meta-analysis-for-last-decade
#8
Tao Wang, Xiao-Ming Tian, Si-Kai Liu, Hui Wang, Ying-Ze Zhang, Wen-Yuan Ding
PURPOSE: We aim to perform a meta-analysis on prevalence of all kinds of operation-related complications following surgery treating cervical compressive myelopathy (CCM) and to provide reference for surgeons making surgical plan. METHODS: An extensive search of literature was performed in PubMed/MEDLINE, Embase, the Cochrane library, CNKI, and WANFANG databases on incidence of operation-related complications from January 2007 to November 2016. Data was calculated and data analysis was conducted with STATA 12...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28304238/remote-motor-system-metabolic-profile-and-surgery-outcome-in-cervical-spondylotic-myelopathy
#9
Sorin C Craciunas, Mircea R Gorgan, Bogdan Ianosi, Phil Lee, Joseph Burris, Carmen M Cirstea
OBJECTIVE In patients with cervical spondylotic myelopathy (CSM), the motor system may undergo progressive functional/structural changes rostral to the lesion, and these changes may be associated with clinical disability. The extent to which these changes have a prognostic value in the clinical recovery after surgical treatment is not yet known. In this study, magnetic resonance spectroscopy (MRS) was used to test 2 primary hypotheses. 1) Based on evidence of corticospinal and spinocerebellar, rubro-, or reticulospinal tract degeneration/dysfunction during chronic spinal cord compression, the authors hypothesized that the metabolic profile of the primary motor cortices (M1s) and cerebellum, respectively, would be altered in patients with CSM, and these alterations would be associated with the extent of the neurological disabilities...
June 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28289891/selective-laminectomy-for-cervical-spondylotic-myelopathy-a-comparative-analysis-with-laminoplasty-technique
#10
Han Chang, Choll Kim, Byung-Wan Choi
INTRODUCTION: The purpose of this study was to evaluate the effectiveness of selective laminectomy compared with laminoplasty for patients with multilevel cervical spondylotic myelopathy (CSM) by evaluating the radiological and clinical outcomes. METHODS: We retrospectively reviewed 67 patients with who underwent posterior laminectomy (LN) or laminoplasty (LP). LN was performed in 32 cases and LP in 35 cases. Radiologically, we evaluated the neutral C2-7 Cobb angle and range of motion (ROM) preoperatively and at final follow-up...
May 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28285113/ayurvedic-management-in-cervical-spondylotic-myelopathy
#11
Sarvesh Kumar Singh, Kshipra Rajoria
The age related spondylotic changes may result in direct compressive and ischemic dysfunction of the spinal cord known as cervical spondylotic myelopathy (CSM). Symptoms often develop insidiously and are characterized by neck stiffness, unilateral or bilateral deep aching neck, arm and shoulder pain, and possibly stiffness or clumsiness while walking. The management available in current mainstream medicine is not satisfactory. Various Ayurvedic treatments have been in use for these manifestations. We present a case of CSM, which was treated with a combination of Panchakarma procedures and Ayurvedic oral drugs...
January 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28260398/improved-diagnosis-of-cervical-spondylotic-myelopathy-with-contact-heat-evoked-potentials
#12
Catherine R Jutzeler, Anett Ulrich, Barbara Huber, Jan Rosner, John L K Kramer, Armin Curt
The aim of this study was to reveal the sensitivity and responsiveness of contact heat evoked potentials (CHEPs) to assess cervical spondylotic myelopathy (CSM). A total of 81 patients with clinically and radiologically confirmed spinal cord compression were reviewed. All patients underwent full clinical examinations with combined recordings of segmental CHEPs and somatosensory evoked potentials (dSSEPs) compared with healthy controls. Cross-sectional area, maximal canal compression, and maximal spinal cord compression were determined based on T2-weighted MRI...
June 15, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28247081/extraordinary-positional-cervical-spinal-cord-compression-in-extension-position-as-a-rare-cause-of-postoperative-progressive-myelopathy-after-cervical-posterior-laminoplasty-detected-using-the-extension-flexion-positional-ct-myelography-one-case-after-laminectomy
#13
Yasushi Fujiwara, Hideki Manabe, Takahiro Harada, Bunichiro Izumi, Nobuo Adachi
PURPOSE: Posterior cervical laminectomies and laminoplasties are common treatments for cervical spondylotic myelopathy. However, recent studies demonstrated that positional spinal cord compression occurred after cervical laminectomies and caused postoperative progressive myelopathy. Although there were no such reports after laminoplasties, we report two cases in which symptomatic extraordinary positional spinal cord compression occurred after laminoplasties in this paper. METHODS: This study included two patients who showed progressive myelopathy: one case after a laminectomy following failure of a single-door laminoplasty and one case after a double-door laminoplasty without interlaminar spacers...
May 2017: European Spine Journal
https://www.readbyqxmd.com/read/28243365/does-segmental-kyphosis-affect-surgical-outcome-after-a-posterior-decompressive-laminectomy-in-multisegmental-cervical-spondylotic-myelopathy
#14
Akshay Jain, Tarush Rustagi, Gautam Prasad, Tushar Deore, Shekhar Y Bhojraj
STUDY DESIGN: Retrospective analysis. PURPOSE: To compare results of laminectomy in multisegmental compressive cervical myelopathy (CSM) with lordosis versus segmental kyphosis. OVERVIEW OF LITERATURE: Laminectomy is an established procedure for decompression in CSM with cervical lordosis. However in patients with segmental kyphosis, it is associated with risk of progression of kyphosis and poor outcome. Whether this loss of sagittal alignment affects functional outcome is not clear...
February 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28130164/does-dynamic-supine-magnetic-resonance-imaging-improve-the-diagnostic-accuracy-of-cervical-spondylotic-myelopathy-a-review-of-the-current-evidence
#15
REVIEW
Nanfang Xu, Shaobo Wang, Huishu Yuan, Xiaoguang Liu, Zhongjun Liu
OBJECTIVE: We aimed to critically analyze the current evidence regarding the role of dynamic supine magnetic resonance imaging (dsMRI) in the evaluation of cervical spondylotic myelopathy. METHODS: Thirteen studies were identified through a comprehensive literature search performed in the PubMed, EMBASE, and ISI databases as fulfilling the inclusion criteria and were reviewed for subject characteristics, radiographic parameters, and salient findings. RESULTS: Studies herein reviewed suggested that dsMRI was able to detect new appearance or increased grade of medullary compression in ≥20% of patients and to demonstrate an average narrowing of the cervical canal by 20% (in comparison with the neutral position)...
April 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28127374/the-change-of-range-of-motion-at-anterior-compression-of-the-cervical-cord-after-laminoplasty-in-patients-with-cervical-spondylotic-myelopathy
#16
Yongjae Cho
OBJECTIVE: Degenerative diseases of the spine, such as cervical spondylotic myelopathy (CSM), are increasing among the old age population, and surgical treatment of CSM is becoming more and more common. The aim of this study was to investigate how functional recovery can be influenced by anterior compression of the spinal cord (ACS) after laminoplasty for treatment of patients with CSM. METHODS: We retrospectively analyzed 32 patients admitted to Ewha Womans Mok-Dong Hospital with CSM who underwent open-door laminoplasty from January 2012 to December 2014...
December 2016: Korean Journal of Spine
https://www.readbyqxmd.com/read/28125929/trans-synaptic-degeneration-of-motoneurons-distal-to-chronic-cervical-spinal-cord-compression-in-cervical-spondylotic-myelopathy
#17
Chaojun Zheng, Yu Zhu, Feizhou Lu, Xiaosheng Ma, Dong Tian, Jianyuan Jiang
OBJECTIVE: To assess the effect of chronic cervical spinal cord compression upon remote motor unit function in patients with cervical spondylotic myelopathy (CSM). METHODS: Fifty-three CSM patients and 47 healthy subjects were included. Bilateral motor unit number estimations (MUNEs) were recorded from both abductor digiti minimi and abductor pollicis brevis, and bilateral flexor carpi radialis (FCR) H-reflexes were examined in all subjects along with the nine-hole peg test (NHPT)...
January 26, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28104259/utility-of-extension-views-in-spondylotic-myelopathy-mimicking-transverse-myelitis
#18
Brittani L Conway, Michelle J Clarke, Timothy J Kaufmann, Eoin P Flanagan
Cervical spondylotic myelopathy is a common cause of myelopathy and may mimic transverse myelitis. We report a 55 year-old lady with subacute myelopathy initially treated with glatiramer acetate for suspected clinically isolated syndrome. MRI head and spine revealed a single short cervical cord T2-hyperintense lesion with enhancement just below a region of moderate stenosis. Cerebrospinal fluid revealed elevated oligoclonal bands. Repeat MRI 7 months later showed persistent enhancement. Dynamic MRI revealed cord compression during extension...
January 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28099187/a-comparative-study-of-anterior-decompression-with-fusion-and-posterior-decompression-with-laminoplasty-for-the-treatment-of-cervical-spondylotic-myelopathy-patients-with-large-anterior-compression-of-the-spinal-cord
#19
Takashi Hirai, Toshitaka Yoshii, Yoshiyasu Arai, Kenichiro Sakai, Ichiro Torigoe, Hidetsugu Maehara, Masaki Tomori, Takashi Taniyama, Hirokazu Sato, Atsushi Okawa
STUDY DESIGN: This is a retrospective observational single-center study. OBJECTIVES: To compare anterior decompression and fusion (ADF) and laminoplasty (LAMP) for the treatment of cervical spondylotic myelopathy (CSM) patients with large anterior compression in terms of clinical and radiologic outcomes. SUMMARY OF BACKGROUND DATA: We have reported that insufficient posterior decompression could be often seen after laminoplasty for CSM patients with preoperative anterior clearance of the spinal cord, defined as an interval <4 mm between the preoperative the modified K-line and anterior structure of the spinal canal at most compressive segment on sagittal T1-weighted magnetic resonance imaging...
January 17, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28076997/surgical-treatment-of-severe-multilevel-circumferential-compressive-myelopathy-of-the-cervical-spine-is-circumferential-procedure-necessary
#20
Xiao-Kang Liu, Hao Li, Jian-Guang Xu, Er-Zhu Yang, Tie-Sheng Hou, Bing-Fang Zeng, Xiao-Feng Lian
OBJECTIVE: To determine the necessity of circumferential decompression and fusion in patients with severe multilevel cervical spondylotic myelopathy with circumferential cord compression. METHODS: This prospective study involved 51 patients with severe multilevel circumferential cervical myelopathy underwent two-stage circumferential procedure between July 2008 and June 2010. VAS scores, satisfaction surveys and JOA scores and imaging studies were obtained. Twenty-three patients (45...
April 2017: British Journal of Neurosurgery
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