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compressive cervical spondylotic myelopathy

T Rikita, N Tanaka, K Nakanishi, N Kamei, N Sumiyoshi, S Kotaka, N Adachi, M Ochi
STUDY DESIGN: Retrospective study. OBJECTIVES: Few studies have reported a relationship between central motor conduction time (CMCT), which evaluates corticospinal function, and degree of spinal cord compression in patients with myelopathy. Thus, there is no consensus on predicting the degree of prolonged CMCT on the basis of the degree of spinal cord compression. If a correlation exists between CMCT and spinal cord compression, then spinal cord compression may be a useful noninvasive clinical indicator of corticospinal function...
November 1, 2016: Spinal Cord
Wei Lin, Yuan Xue, Ying Zhao, Yaqi Zong, Chao Sun, Bo Pei, Pei Wang
PURPOSE: The generation and tissue origination of disc-associated axial pain is still under exploration. This study was performed to evaluate disc-associated axial pain and to explore whether it originates in the disc or its surrounding components. METHODS: A 6-year series of 88 single-level Smith-Robinson disc and posterior longitudinal ligament (PLL) resections performed to treat single-level cervical spondylotic myelopathy was retrospectively examined. All single-level anterior disc decompressions were performed under local infiltration anesthesia; the PLL was not anesthetized to avoid cervical cord block...
October 6, 2016: European Spine Journal
Xiaoxiao Zhou, Pan Cai, Yuwei Li, Haijiao Wang, Shengli Xia, Xiuhui Wang
STUDY DESIGN: A single-center, retrospective, longitudinal matched cohort clinical study of prospectively collected outcomes. OBJECTIVE: To compare retrospectively the clinical outcomes and complications of the posterior approach laminoplasty and single-stage anterior approach laminoplasty combined with anterior cervical corpectomy and fusion and anterior cervical discectomy and fusion for treating patients with cervical spondylotic myelopathy coincident multilevel anterior and posterior compression, known as complex cervical spondylotic myelopathy (cCSM) here...
September 27, 2016: Clinical Spine Surgery
Kiran Talekar, Michael Poplawski, Rahul Hegde, Mougnyan Cox, Adam Flanders
We review the pathophysiology and imaging findings of acute traumatic spinal cord injury (SCI), cervical spondylotic myelopathy, and briefly review the much less common cord herniation as a unique cause of myelopathy. Acute traumatic SCI is devastating to the patient and the costs to society are staggering. There are currently no "cures" for SCI and the only accepted pharmacologic treatment regimen for traumatic SCI is currently being questioned. Evaluation and prognostication of SCI is a demanding area with significant deficiencies, including lack of biomarkers...
October 2016: Seminars in Ultrasound, CT, and MR
Rana S Dhillon, John Parker, Yasir A Syed, Steve Edgley, Adam Young, James W Fawcett, Nick D Jeffery, Robin J M Franklin, Mark R N Kotter
Cervical spondylotic myelopathy (CSM) is the most common spinal cord disorder and a major cause of disability in adults. Improvements following surgical decompression are limited and patients often remain severely disabled. Post mortem studies indicate that CSM is associated with profound axonal loss. However, our understanding of the pathophysiology of CSM remains limited.To investigate the hypothesis that axonal plasticity plays a role in the recovery following surgical decompression, we adopted a novel preclinical model of mild to moderate CSM...
2016: Acta Neuropathologica Communications
Ivana Kovalova, Milos Kerkovsky, Zdenek Kadanka, Zdenek Kadanka, Martin Nemec, Barbora Jurova, Ladislav Dusek, Jiri Jarkovsky, Josef Bednarik
STUDY DESIGN: Cross-sectional population-based observational study. OBJECTIVE: To estimate the prevalence of non-myelopathic spondylotic cervical cord compression (NMSCCC) and cervical spondylotic myelopathy (CSM) in a population above the age of forty and to evaluate the magnetic resonance imaging (MRI) characteristics of these conditions. SUMMARY OF BACKGROUND DATA: The prevalence of neither NMSCCC nor CSM is known and there exists no commonly accepted quantitative MRI definition of cervical cord compression...
August 9, 2016: Spine
Subhadip Mandal, U Banerjee, A S Mukherjee, Subhajyoti Mandal, Srikanta Kundu
BACKGROUND: Chronic compression of the cervical spinal cord leads to a clinical syndrome of cervical spondylotic myelopathy (CSM). Clinical symptoms of cervical spondylotic myelopathy (CSM) or cervical myeloradiculopathies result in spinal cord and root dysfunction. The primary aims of surgical intervention for multilevel myelopathy are to decompress the spinal cord and maintain stability of the cervical spine. Secondary aims are to minimize complications which include long-term pain and motion loss...
2016: International Journal of Spine Surgery
Peter Cowley
Spinal stenosis is common and presents in a variety of forms. Symptomatic lumbar stenosis occurs in approximately 10% of the population and cervical stenosis in 9% over age 70. Imaging is central to the management decision process and first-choice MR imaging may be substituted with CT and CT myelography. A review of the literature is presented with particular emphasis on the clinical-radiologic correlation in both neurogenic intermittent claudication and cervical spondylotic myelopathy. Advanced techniques promise improvements, particularly with radicular compressive lesions, but remain underutilized in routine clinical practice...
August 2016: Magnetic Resonance Imaging Clinics of North America
Weera Chaiyamongkol, Teeranan Laohawiriyakamol, Boonsin Tangtrakulwanich, Pramot Tanutit, Piyawat Bintachitt, Koopong Siribumrungwong
STUDY DESIGN: This study is a diagnostic analysis. OBJECTIVE: To investigate the diagnostic accuracy of Trömner sign in cervical spondylotic myelopathy (CSM), and how its presence correlates with the severity of myelopathy. SUMMARY OF BACKGROUND DATA: A clinical presentation of myelopathy corresponding with image findings is a current standard to diagnose CSM. Trömner sign is an alternative of well-known Hoffmann sign to detect CSM. Little is known about its diagnostic accuracy and how its presence correlates with the severity of CSM...
July 11, 2016: Clinical Spine Surgery
Majid Reza Farrokhi, Fariborz Ghaffarpasand, Mehdi Khani, Mehrnaz Gholami
Cervical spondylotic myelopathy (CSM) is the most common progressive degenerative disease of the spine in geriatric population. Surgery remains the mainstay of the treatment in patients with CSM. The surgical approach should be based on cervical sagittal imbalance. In patients with effective cervical lordosis (fewer than 3 levels of ventral disease), the anterior cervical discectomy and fusion (ACDF) or arthroplasty is preferred. Patients with more than 3 levels of compression are generally treated by laminoplasty, especially with preserved lordotic curvature...
July 4, 2016: World Neurosurgery
Guoyun Bu, Feng Shuang, Gang Liu, Ye Wu, Shuxun Hou, Dongfeng Ren, Weilin Shang
OBJECTIVES: We designed a novel surgical strategy named one-stage selective discectomy combined with expansive hemilaminectomy (OSDEHL) which might theoretically reduce the postoperative complications of Cervical Spondylotic Myelopathy (CSM). The objectives of this study is to evaluate its efficacy and safety. METHODS: 62 patients with CSM were enrolled in this study. The procedure includes selective discectomy with fusion at 1 or 2 segments of maximal cord compression and expansive hemilaminectomy on the symptomatic or severe side of the body...
June 20, 2016: World Neurosurgery
Seiji Okada, Charles Chang, Geraldine Chang, James J Yue
BACKGROUND CONTEXT: Venous hypertensive myelopathy (VHM) results from spinal vascular malformations of arteriovenous shunting that increases spinal venous pressure, leading to congestive edema and neurologic dysfunction. There has been no report of VHM associated with cervical spondylotic myelopathy (CSM). PURPOSE: The aim of this study was to report an extremely rare case of VHM likely due to CSM. STUDY DESIGN: This study is a case report and review of the literature...
June 9, 2016: Spine Journal: Official Journal of the North American Spine Society
Indira Devi Bhagavatula, Dhananjaya I Bhat, Gopalakrishnan M Sasidharan, Rakesh Kumar Mishra, Praful Suresh Maste, George C Vilanilam, Talakkad N Sathyaprabha
OBJECTIVE Respiratory abnormalities are well documented in acute spinal cord injury; however, the literature available for respiratory dysfunction in chronic compressive myelopathy (CCM) is limited. Respiratory dysfunction in CCM is often subtle and subclinical. The authors studied the pattern of respiratory dysfunction in patients with chronic cord compression by using spirometry, and the clinical and surgical implications of this dysfunction. In this study they also attempted to address the postoperative respiratory function in these patients...
June 2016: Neurosurgical Focus
Indira Devi Bhagavatula, Dhaval Shukla, Nishanth Sadashiva, Praveen Saligoudar, Chandrajit Prasad, Dhananjaya I Bhat
OBJECTIVE The physiological mechanisms underlying the recovery of motor function after cervical spondylotic myelopathy (CSM) surgery are poorly understood. Neuronal plasticity allows neurons to compensate for injury and disease and to adjust their activities in response to new situations or changes in their environment. Cortical reorganization as well as improvement in corticospinal conduction happens during motor recovery after stroke and spinal cord injury. In this study the authors aimed to understand the cortical changes that occur due to CSM and following CSM surgery and to correlate these changes with functional recovery by using blood oxygen level-dependent (BOLD) functional MRI (fMRI)...
June 2016: Neurosurgical Focus
R Nardone, Y Höller, F Brigo, V N Frey, P Lochner, S Leis, S Golaszewski, E Trinka
STUDY DESIGN: Topical review of the literature. OBJECTIVE: The objective of this review article was to assess indications and usefulness of various neurophysiological techniques in diagnosis and management of cervical spondylogenic myelopathy (CSM). METHODS: The MEDLINE, accessed by Pubmed and EMBASE electronic databases, was searched using the medical subject headings: 'compressive myelopathy', 'cervical spondylotic myelopathy (CSM)', 'cervical spondylogenic myelopathy', 'motor evoked potentials (MEPs)', 'transcranial magnetic stimulation', 'somatosensory evoked potentials (SEPs)', 'electromyography (EMG)', 'nerve conduction studies (NCS)' and 'cutaneous silent period (CSP)'...
October 2016: Spinal Cord
M Provencher, A Habing, S A Moore, L Cook, G Phillips, R C da Costa
BACKGROUND: The dynamic component of disc-associated cervical spondylomyelopathy (DA-CSM) currently is evaluated using traction magnetic resonance imaging (MRI), which does not assess changes in flexion and extension of the cervical vertebral column. In humans with cervical spondylotic myelopathy, kinematic MRI is used to identify dynamic compressions. HYPOTHESIS/OBJECTIVES: To evaluate the feasibility and utility of kMRI in Doberman Pinschers with DA-CSM using a novel positioning device...
July 2016: Journal of Veterinary Internal Medicine
Soo Eon Lee, Chun Kee Chung, Chi Heon Kim
We conducted a prospective randomized study comparing stand-alone cage and bone autograft and plate implants in anterior cervical discectomy and fusion (, NCT01011569). Our interim analysis showed autologous bone graft with plating was superior to a stand-alone cage for segmental lordosis. During this analysis, we noted a difference in canal encroachment by the fusion mass between the two fusion groups. A narrow cervical spinal canal is an important factor in the development of cervical spondylotic myelopathy, therefore this unexpected potential risk of spinal cord compression necessitated another interim analysis to investigate whether there was a difference in canal encroachment by the fusion mass between the two groups...
July 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Hironobu Sakaura, Toshitada Miwa, Yusuke Kuroda, Tetsuo Ohwada
OBJECTIVE The authors recently reported that the presence of chronic kidney disease (CKD) and/or extended abdominal aortic calcification was associated with significantly worse clinical outcomes after posterior lumbar interbody fusion. CKD is one of the highest risk factors for systemic atherosclerosis. Therefore, impaired blood flow due to atherosclerosis could exacerbate degeneration of the cervical spine and neural tissue. However, there has been no report of a study evaluating the deleterious effects of CKD and atherosclerosis on the outcomes after decompression surgery for cervical compression myelopathy...
May 27, 2016: Journal of Neurosurgery. Spine
Sandy Goncalves, Todd K Stevens, Patricia Doyle-Pettypiece, Robert Bartha, Neil Duggal
OBJECTIVE Cervical spondylotic myelopathy (CSM) is the most common cause of reversible spinal cord dysfunction in people over the age of 55 years. Following surgery for symptomatic CSM, patients demonstrate motor improvement early in the postoperative course, whereas sensory improvement can lag behind. The authors of the present study hypothesized that changes in the concentration of N-acetylaspartate (NAA) in the motor and sensory cortices in the brain would emulate the time course of neurological recovery following decompression surgery for CSM...
May 13, 2016: Journal of Neurosurgery. Spine
Tsukasa Kanchiku, Yasuaki Imajo, Hidenori Suzuki, Yuichiro Yoshida, Kosuke Akashi, Toshihiko Taguchi
STUDY DESIGN: Retrospective study. OBJECTIVES: The objective of this study was to examine whether the morphology of the compressed spinal cord reflects spinal cord dysfunction in cervical spondylotic myelopathy (CSM). SUMMARY OF BACKGROUND: Segmental levels responsible for clinical symptoms in CSM are usually diagnosed by neurological examination and imaging studies such as magnetic resonance imaging (MRI). Electrophysiological examination makes it possible to assess the spinal cord function quantitatively...
December 2016: Clinical Spine Surgery
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