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https://www.readbyqxmd.com/read/27918337/the-effects-of-a-genital-vibratory-stimulation-device-on-sexual-function-and-genital-sensation
#1
Marsha K Guess, Kathleen A Connell, Scott Chudnoff, Olusola Adekoya, Cherrilyn Richmond, Kayla E Nixon, Katherine Freeman, Arnold Melman
OBJECTIVE: The aim of this study was to evaluate the effectiveness of a genital vibratory stimulation device in improving sexual function in women with arousal and orgasm disorders. METHODS: In this single-arm, prospective study, baseline and 1- and 3-month assessments were performed to evaluate women with sexual arousal and/or orgasmic disorders, who received therapy using a genital vibratory stimulation device. Sexual function, satisfaction, and distress were evaluated using the Female Sexual Function Index (FSFI), the Female Sexual Distress Scale, and the Female Intervention Efficacy Index questionnaires...
December 1, 2016: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/27914563/differential-effects-of-testosterone-and-estradiol-on-clitoral-function-an-experimental-study-in-rats
#2
Paolo Comeglio, Ilaria Cellai, Sandra Filippi, Chiara Corno, Francesca Corcetto, Annamaria Morelli, Elena Maneschi, Elisa Maseroli, Edoardo Mannucci, Massimiliano Fambrini, Mario Maggi, Linda Vignozzi
INTRODUCTION: Female sexual response is a complex phenomenon in which psychological, neurologic, and vascular mechanisms and hormonal factors interact. During the arousal phase, they cooperate to increase genital blood flow, thus inducing engorgement of the clitoris and lubrication of the vagina. Regulation of vascular and non-vascular smooth muscle tone is the crucial event in the erectile process. Preclinical studies have suggested that nitric oxide (NO) is the main vasodilator neurotransmitter modulating, through the second messenger cyclic guanosine monophosphate (cGMP), clitoral flow vessels...
December 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27913889/ocular-pharmacology-of-tear-film-dry-eye-and-allergic-conjunctivitis
#3
Shilpa Gulati, Sandeep Jain
Dry Eye Disease (DED) is "a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance, and tear-film instability with potential damage to the ocular surface." DED comprises two etiologic categories: aqueous-deficient dry eye (ADDE) and evaporative dry eye (EDE). Diagnostic workup of DED should include clinical history, symptom questionnaire, fluorescein TBUT, ocular surface staining grading, Schirmer I/II, lid and meibomian pathology, meibomian expression, followed by other available tests...
December 3, 2016: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/27911782/egfr-signaling-is-critical-for-maintaining-the-superficial-layer-of-articular-cartilage-and-preventing-osteoarthritis-initiation
#4
Haoruo Jia, Xiaoyuan Ma, Wei Tong, Basak Doyran, Zeyang Sun, Luqiang Wang, Xianrong Zhang, Yilu Zhou, Farid Badar, Abhishek Chandra, X Lucas Lu, Yang Xia, Lin Han, Motomi Enomoto-Iwamoto, Ling Qin
Osteoarthritis (OA) is the most common joint disease, characterized by progressive destruction of the articular cartilage. The surface of joint cartilage is the first defensive and affected site of OA, but our knowledge of genesis and homeostasis of this superficial zone is scarce. EGFR signaling is important for tissue homeostasis. Immunostaining revealed that its activity is mostly dominant in the superficial layer of healthy cartilage but greatly diminished when OA initiates. To evaluate the role of EGFR signaling in the articular cartilage, we studied a cartilage-specific Egfr-deficient (CKO) mouse model (Col2-Cre EgfrWa5/flox)...
November 28, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27911562/macroscopic-model-for-head-on-binary-droplet-collisions-in-a-gaseous-medium
#5
Jie Li
In this Letter, coalescence-bouncing transitions of head-on binary droplet collisions are predicted by a novel macroscopic model based entirely on fundamental laws of physics. By making use of the lubrication theory of Zhang and Law [Phys. Fluids 23, 042102 (2011)], we have modified the Navier-Stokes equations to accurately account for the rarefied nature of the interdroplet gas film. Through the disjoint pressure model, we have incorporated the intermolecular van der Waals forces. Our model does not use any adjustable (empirical) parameters...
November 18, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27902352/cohnella-lubricantis-sp-nov-isolated-from-a-coolant-lubricant-solution
#6
Peter Kämpfer, Stefanie P Glaeser, Hans-Jürgen Busse
A Gram-staining-positive, aerobic, non-endospore forming organism, isolated from a coolant lubricant solution was studied for its taxonomic position. On the basis of 16S rRNA gene sequence similarity comparisons, strain KSS-154-50T was grouped into the genus Cohnella, most closely related to Cohnella formosensis ALFALFA-35T (97.3 %), Cohnella rhizosphaerae CSE-5610T (97.1 %) and Cohnella nanjingensis D-45T (97.0%). The 16S rRNA gene sequence similarity to other Cohnella species was < 97.0 %. The fatty acid profile from whole cell hydrolysates was very similar to those reported for other Cohnella species supported the allocation to the genus Cohnella...
November 9, 2016: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/27901546/poroelasticity-driven-lubrication-in-hydrogel-interfaces
#7
Erik R Reale, Alison C Dunn
It is widely accepted that hydrogel surfaces are slippery, and have low friction, but dynamic applied stresses alter the hydrogel composition at the interface as water is displaced. The induced osmotic imbalance of compressed hydrogel which cannot swell to equilibrium should drive the resistance to slip against it. This paper demonstrates the driving role of poroelasticity in the friction of hydrogel-glass interfaces, specifically how poroelastic relaxation of hydrogels increases adhesion. We translate the work of adhesion into an effective surface energy density that increases with the duration of applied pressure from 10 to 50 mJ m(-2), as measured by micro-indentation...
November 30, 2016: Soft Matter
https://www.readbyqxmd.com/read/27898302/a-novel-sandwich-type-traveling-wave-piezoelectric-tracked-mobile-system
#8
Liang Wang, Chengyou Shu, Quan Zhang, Jiamei Jin
In this paper, a novel sandwich-type traveling wave piezoelectric tracked mobile system was proposed, designed, fabricated and experimentally investigated. The proposed system exhibits the advantages of simple structure, high mechanical integration, lack of electromagnetic interference, and lack of lubrication requirement, and hence shows potential application to robotic rovers for planetary exploration. The tracked mobile system is comprised of a sandwich actuating mechanism and a metal track. The actuating mechanism includes a sandwich piezoelectric transducer and two annular parts symmetrically placed at either end of the transducer, while the metal track is tensioned along the outer surfaces of the annular parts...
November 15, 2016: Ultrasonics
https://www.readbyqxmd.com/read/27892918/effect-of-diaphragm-and-lubricant-gel-provision-on-human-papillomavirus-infection-among-women-provided-with-condoms-a-randomized-controlled-trial-correction
#9
(no author information available yet)
No abstract text is available yet for this article.
August 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27892582/lubrication-of-chocolate-during-oral-processing
#10
S A Rodrigues, N Selway, M P Morgenstern, L Motoi, J R Stokes, B J James
The structure of chocolate is drastically transformed during oral processing from a composite solid to an oil/water fluid emulsion. Using two commercial dark chocolates varying in cocoa solids content, this study develops a method to identify the factors that govern lubrication in molten chocolate and saliva's contribution to lubrication following oral processing. In addition to chocolate and its individual components, simulated boluses (molten chocolate and phosphate buffered saline), in vitro boluses (molten chocolate and whole human saliva) and ex vivo boluses (chocolate expectorated after chewing till the point of swallow) were tested...
November 28, 2016: Food & Function
https://www.readbyqxmd.com/read/27891319/hyaluronic-acid-hope-of-light-to-black-triangles
#11
Jyotsana Tanwar, Shital A Hungund
Interdental papilla construction, especially in the esthetic area, is one of the most challenging tasks. Interdental papilla loss might occur due to several reasons as a consequence of periodontal surgery or trauma. The purpose of this study is to report the reconstruction of lost interdental papilla using hyaluronic acid gel. Hyaluronic acid is a glycosaminoglycan molecule with anti-inflammatory, anti-edematous properties on periodontal tissues invaded by submicrobial flora. It enhances wound healing and accelerates periodontal repair and regeneration...
September 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/27890244/development-and-optimization-of-a-wet-granulation-process-at-elevated-temperature-for-a-poorly-compactible-drug-using-twin-screw-extruder-for-continuous-manufacturing
#12
Anuprabha K Meena, Divyakant Desai, Abu T M Serajuddin
The objective of this study was to enhance tabletability of a poorly compactible drug, acetaminophen, by wet granulation using twin screw extruder at high temperature. It was desired that there would be minimum amounts of excipients used and the granules obtained after extrusion would be dry and fall within a size range suitable for tableting without any further processing. Mixtures of acetaminophen (95%) with binders (5% povidone or partially pregelatinized starch) were wet granulated through twin screw extruder at 70°C by adding 7% w/w water...
November 24, 2016: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27887828/occupational-health-risk-assessment-and-exposure-to-floor-dust-pahs-inside-an-educational-building
#13
Androniki Maragkidou, Sharif Arar, Afnan Al-Hunaiti, Yuning Ma, Stuart Harrad, Omar Jaghbeir, Dina Faouri, Kaarle Hämeri, Tareq Hussein
Polycyclic aromatic hydrocarbons (PAHs) settled in floor dust play an important role in human health. Although many studies investigated occupational exposure to PAHs, no attempts have been made to report PAHs concentrations as well as their health risk assessment inside an educational building in Jordan. Therefore, the main objective of this study is to report the PAHs concentrations in floor dust and evaluate their exposure and health risk inside the Department of Physics of the University of Jordan. The total PAHs concentrations ranged from 714 to 5246ng/g...
November 22, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27887662/the-effects-of-water-lubrication-of-tracheal-tubes-on-post-intubation-airway-complications-study-protocol-for-a-randomized-controlled-trial
#14
Eugene Kim, Seong Mi Yang, So Jeong Yoon, Jae-Hyon Bahk, Jeong-Hwa Seo
BACKGROUND: Water is known to have lubricating properties, thus it is used for lubrication of tracheal tubes to reduce airway injuries caused by intubation. However, there is no definite evidence to substantiate the beneficial effects of lubricating tracheal tubes using water for attenuating airway injuries. Moreover, the lubrication pretreatment may cause contamination of the tube, leading to respiratory infections. Therefore, this trial aims to assess whether no pretreatment of tracheal tubes does not increase post-intubation airway complications as compared with water lubrication of tubes...
November 25, 2016: Trials
https://www.readbyqxmd.com/read/27883990/force-distance-curves-on-lubricant-films-an-approach-to-the-characterization-of-the-shape-of-the-afm-tip
#15
Brunero Cappella
Force-distance curves have been acquired with an atomic force microscope on perfluorpolyether films. It is shown that curves acquired on films of different thickness, at different rates and with different dwell times can be overlapped by rescaling the time or distance axis. When the time or distance axis is rescaled, the force depends only on the surface tension of perfluorpolyether and on geometrical properties of the tip (aperture and perimeter of the tip at a given distance from the apex). Hence, curves acquired with the same tip overlap...
November 15, 2016: Micron: the International Research and Review Journal for Microscopy
https://www.readbyqxmd.com/read/27882973/the-evolving-quality-of-frictional-contact-with-graphene
#16
Suzhi Li, Qunyang Li, Robert W Carpick, Peter Gumbsch, Xin Z Liu, Xiangdong Ding, Jun Sun, Ju Li
Graphite and other lamellar materials are used as dry lubricants for macroscale metallic sliding components and high-pressure contacts. It has been shown experimentally that monolayer graphene exhibits higher friction than multilayer graphene and graphite, and that this friction increases with continued sliding, but the mechanism behind this remains subject to debate. It has long been conjectured that the true contact area between two rough bodies controls interfacial friction. The true contact area, defined for example by the number of atoms within the range of interatomic forces, is difficult to visualize directly but characterizes the quantity of contact...
November 23, 2016: Nature
https://www.readbyqxmd.com/read/27881806/how-do-gloves-affect-cutaneous-sensibility-in-medical-practice-two-new-applied-tests
#17
Peter Mylon, Matt J Carré, Nicolas Martin, Roger Lewis
In order to quantify the effect of medical gloves on tactile performance, two new Simulated Medical Examination Tactile Tests (SMETT) have been developed to replicate the tactile and haptic ability required in medical examinations: the 'Bumps' test and the 'Princess and the Pea' (P&P) test. A pilot study was carried out using 30-40 subjects for each test in order to investigate the suitability of the tests for medical glove evaluation. Tests were performed with latex and nitrile examination gloves and without gloves...
November 23, 2016: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/27879379/performance-of-the-pneux-system-a-bench-study-comparison-with-4-other-endotracheal-tube-cuffs
#18
Christopher T Chenelle, Taiga Itagaki, Daniel F Fisher, Lorenzo Berra, Robert M Kacmarek
BACKGROUND: Cuff design affects microaspiration, a risk factor for pneumonia. We questioned whether the PneuX low-volume fold-free cuff design would prevent cuff leakage and maintain the same tracheal wall pressure as high-volume, low-pressure (HVLP) cuffs. METHODS: We evaluated 4 HVLP-cuffed endotracheal tubes (ETTs), Hi-Lo (polyvinyl chloride [PVC]), Microcuff (polyurethane [PU]), SealGuard (PU+tapered), and TaperGuard (PVC+tapered), and the PneuX with its dedicated tracheal seal monitor...
November 22, 2016: Respiratory Care
https://www.readbyqxmd.com/read/27879061/patterned-slips-for-the-formation-of-arrays-of-biofilm-microclusters-with-defined-geometries
#19
Julia Bruchmann, Ivana Pini, Tejeshwar S Gill, Thomas Schwartz, Pavel A Levkin
Biofilms represent an immense problem in medicine due to their strong drug-resistant properties and inherent stress-response activities. Due to the inhomogeneous and very complex architectures of large biofilm aggregates, biofilm studies often suffer from low reproducibility. In this study, an approach to form arrays of homogeneous biofilm microclusters with defined 2D geometries is presented. The method is based on the formation of water-infused hydrophilic porous polymer areas with precise geometries separated by "slippery" lubricant-infused porous surface (SLIPS)...
November 23, 2016: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/27877859/self-lubricating-low-friction-wear-resistant-al-based-quasicrystalline-coatings
#20
Bruno Alessandro Silva Guedes de Lima, Rodinei Medeiros Gomes, Severino Jackson Guedes de Lima, Diana Dragoe, Marie-Geneviève Barthes-Labrousse, Richard Kouitat-Njiwa, Jean-Marie Dubois
After gas atomization, a quasicrystalline powder based on aluminium was used to prepare a thick coating by high-velocity oxygen-fuel flame torch spraying. This layer was deposited on top of a bond-coat layer on a steel plate. A post-spraying annealing treatment turned the two layers to their stable state, a γ-brass crystal and an icosahedral quasicrystal, respectively. The projection parameters were selected in such a way that the coating behaved like a self-lubricating material, which offered very good wear resistance (duration of pin-on-disk tests superior to 5 km with negligible material loss) and low friction (µ ≤ 6% against sintered tungsten carbide), in contrast to the state of the art...
2016: Science and Technology of Advanced Materials
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