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https://www.readbyqxmd.com/read/28650336/design-and-content-determination-of-genhuang-dispersible-tablet-herbal-formulation
#1
Rui-Hua Xin, Ge Liang, Ji-Fang Zheng
The aim of the present study was to optimize the shaping technology of the traditional herbal formula Genhuang dispersible tablets, and also establish a method for content determination. The optimal formulation of Genhuang dispersible tablets was determined based on the results of single factor test and orthogonal design test. The disintegration was used as the main study indicator. The proportion of each adjuvant in the optimal formulation consisted of 40% MCC as bulking agent, 15% PVPP and 7% L-HPC as disintegrant, ethanol as adhesive, CSD as lubricant, preparing the dispersible tablets with wet granulation...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28649870/lubricant-provides-poor-rectal-mucosal-hiv-coverage
#2
Eugenie C Shieh, Ethel D Weld, Edward J Fuchs, Hiwot Hiruy, Karen W Buckheit, Robert W Buckheit, Jennifer C Breakey, Craig W Hendrix
Given the rising HIV incidence in men who have sex with men (MSM) despite repeatedly proven effectiveness of oral HIV pre-exposure prophylaxis, behaviorally-congruent periodic dosing strategies, such as dosing microbicides as lubricants, are now in demand. Rectal microbicide gel studies largely administer gels using vaginal applicators, which have not been well-received and do not mimic lubricant use. We compared rectal gel manually dosed as lubricant to applicator dosing in five healthy, HIV-negative MSM who received 10 or 3...
June 25, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28649098/-aging-and-homeostasis-aging-of-articular-cartilage-and-chondrocytes
#3
Takehiko Matsushita, Toshikazu Tanaka
Articular cartilage is an important structure contributing to shock absorption and joint lubrication. Aging and trauma cause loss of function of articular cartilage, resulting in osteoarthritis(OA). Chondrocyte, the only type of the cell that resides in the articular cartilage. Recent studies have revealed that aging-associated changes in chondrocytes are important causative factors of OA. This review describes various mechanism and factors involved in aging of articular cartilage and chondrocytes.
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28647423/sterilizing-service-unit-packing-area-to-glove-or-regular-hand-hygiene-that-is-the-question
#4
Dayane de Melo Costa, Lillian Kelly de Oliveira Lopes, Anaclara Ferreira Veiga Tipple, Roel Beltran Castillo, Honghua Hu, Anand Kumar Deva, Karen Vickery
BACKGROUND: During functionality testing and packaging of reusable surgical instruments (RSI) for sterilisation, instruments are frequently touched. Considering the lack of standards relating to hand hygiene frequency and use of gloves in the sterilising service unit packing area, we aimed to determine the effect of hand hygiene and glove use on maintenance of RSI cleanliness. METHODS: Following manual and automated cleaning, Halsted-mosquito forceps were assessed for adenosine triphosphate (ATP), protein and microbial contamination after handling with gloved and ungloved but washed hands utilising an ATP surface swab test, bicinchoninic acid assay, and standard culture plate/broth, respectively...
June 21, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28647146/analysis-of-oxidised-heavy-paraffininc-products-by-high-temperature-comprehensive-two-dimensional-gas-chromatography
#5
H Potgieter, R Bekker, J Beigley, E Rohwer
Heavy petroleum fractions are produced during crude and synthetic crude oil refining processes and they need to be upgraded to useable products to increase their market value. Usually these fractions are upgraded to fuel products by hydrocracking, hydroisomerization and hydrogenation processes. These fractions are also upgraded to other high value commercial products like lubricant oils and waxes by distillation, hydrogenation, and oxidation and/or blending. Oxidation of hydrogenated heavy paraffinic fractions produces high value products that contain a variety of oxygenates and the characterization of these heavy oxygenates is very important for the control of oxidation processes...
June 16, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28644394/synergistic-effect-of-mos%C3%A2-and-sio%C3%A2-nanoparticles-as-lubricant-additives-for-magnesium-alloy-steel-contacts
#6
Hongmei Xie, Bin Jiang, Xingyu Hu, Cheng Peng, Hongli Guo, Fusheng Pan
The tribological performances of the SiO₂/MoS₂ hybrids as lubricant additives were explored by a reciprocating ball-on-flat tribometer for AZ31 magnesium alloy/AISI 52100 bearing steel pairs. The results demonstrated that the introduction of SiO₂/MoS₂ hybrids into the base oil exhibited a significant reduction in the friction coefficient and wear volume as well as an increase in load bearing capacity, which was better than the testing results of the SiO₂ or MoS₂ nanolubricants. Specifically, the addition of 0...
June 23, 2017: Nanomaterials
https://www.readbyqxmd.com/read/28636330/water-in-ionic-liquid-lubricants-friend-and-foe
#7
Oscar Y Fajardo, Fernando Bresme, Alexei A Kornyshev, Michael Urbakh
To a greater or lesser extent, most room-temperature ionic liquids (RTILs) absorb water from humid air. Penetration of water into the lubricating nanoscale film may affect its equilibrium structure and dynamic properties and thus influence the ability of RTILs as lubricants to reduce friction between solid surfaces. Here we investigate the impact of hydration on lubrication using nonequilibrium molecular dynamics simulations. Water adsorption changes both the ionic liquid molecules' orientation and the slip conditions at the solid-liquid interfaces, resulting in a reduced resistance against squeezing-out of the lubricant by an external load...
June 26, 2017: ACS Nano
https://www.readbyqxmd.com/read/28636252/influence-of-analyzed-lubricant-volumes-on-the-amount-and-characteristics-of-generated-wear-particles-from-three-different-types-of-polyethylene-liner-materials
#8
Jana Markhoff, Carmen Zietz, Christian Fabry, Gerhard Fulda, Rainer Bader
The articulating components of artificial joints consist mainly of metals, ceramics, or polymers. Resulting abrasive wear particles can promote osteolysis and aseptic loosening of the endo-prosthetic implants. Ultra-high-molecular-weight-polyethylene is the material used most for bearing couples in total hip replacement. In the present study, three types of polyethylene (PE) liners varying in material composition, i.e., (1) conventional PE (C-PE), (2) sequentially cross-linked PE (SX-PE), (3) cross-linked PE blended with vitamin E (EX-PE) articulating with two types of femoral heads were used...
June 21, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28635309/rheumatoid-arthritis-is-associated-with-negatively-variable-impacts-on-domains-of-female-sexual-function-evidence-from-a-systematic-review-and-meta-analysis
#9
Qiuxiang Zhang, Congcong Zhou, Haoyang Chen, Qian Zhao, Lin Li, Yafei Cui, Biyu Shen
To systematically review the literature to identify the impact of rheumatoid arthritis (RA) on specific female sexual function domains. A meta-analysis was performed and the related literature were searched in MEDLINE, EMBASE, Cochrane Library, CNKI, CBM and Web of Science databases, and in reference lists of articles and systematic reviews. Score of the Female Sexual Function Index (FSFI) was used as the outcome measurement, and mean differences (MD) with 95% confidence intervals (CI) were calculated. Five studies were included, including 346 women with RA and 237 healthy female controls...
June 21, 2017: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/28635258/mucin-inspired-lubrication-on-hydrophobic-surfaces
#10
Benjamin Tillmann Käsdorf, Florian Weber, Georgia Petrou, Vaibhav Srivastava, Thomas Crouzier, Oliver Lieleg
In the human body, high molecular weight glycoproteins called mucins play a key role in protecting epithelial surfaces against pathogenic attack, controlling the passage of molecules towards the tissue and enabling boundary lubrication with very low friction coefficients. However, neither the molecular mechanisms nor the chemical motifs of those biomacromolecules involved in these fundamental processes are fully understood. Thus, identifying the key features that render biomacromolecules such as mucins outstanding boundary lubricants could set the stage for creating versatile artificial superlubricants...
June 21, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28633387/anal-intercourse-among-female-sex-workers-in-c%C3%A3-te-d-ivoire-prevalence-determinants-and-model-based-estimates-of-the-population-level-impact-on-hiv-transmission
#11
Mathieu Maheu-Giroux, Stefan Baral, Juan F Vesga, Daouda Diouf, Souleymane Diabaté, Michel Alary, Kouamé Abo, Marie-Claude Boily
Current evidence suggests that anal intercourse (AI) during sex work is common in sub-Saharan Africa, but few studies investigated the contribution of heterosexual AI to HIV epidemics. Using a respondent-driven sampling survey of female sex workers (FSW) in Abidjan (2014), we estimated AI prevalence and frequency. Poisson regressions were used to identify AI determinants. About 20% of FSW (N = 466) engaged in AI during a normal week (95% confidence intervals: 15-26%). Women who performed AI were generally younger, had been selling sex for longer, were born in Côte d'Ivoire, reported higher sex-work income, more frequent sex in public places, and violence from clients than women not reporting AI...
June 14, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28632986/atom-probe-tomography-unveils-formation-mechanisms-of-wear-protective-tribofilms-by-zddp-ionic-liquid-and-their-combination
#12
Wei Guo, Yan Zhou, Xiahan Sang, Donovan N Leonard, Jun Qu, Jonathan D Poplawsky
The development of advanced lubricant additives has been a critical component for in paving the way for increasing energy efficiency and durability for numerous industry applications. However, the formation mechanisms of additive-induced protective tribofilms are not yet fully understood due to the complex chemomechanical interactions at the contact interface and the limited spatial resolution of many characterizing techniques currently used. Here, the tribofilms on a grey cast iron surface formed by three antiwear additives are systematically studied; a phosphonium-phosphate ionic liquid (IL), a zinc dialkyldithiophosphate (ZDDP), and an IL+ZDDP combination...
June 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28632793/the-prevalence-and-correlates-of-low-sexual-functioning-in-women-on-hemodialysis-a-multinational-cross-sectional-study
#13
Valeria Saglimbene, Patrizia Natale, Suetonia Palmer, Marco Scardapane, Jonathan C Craig, Marinella Ruospo, Letizia Gargano, Giuseppe Lucisano, Marietta Török, Eduardo Celia, Rubén Gelfman, Anna Bednarek-Skublewska, Jan Dulawa, Paul Stroumza, Miguel Leal, Domingo Del Castillo, Angelo Marco Murgo, Staffan Schon, Charlotta Wollheim, Jörgen Hegbrant, Giovanni F M Strippoli
Sexual dysfunction may affect 80% of women in hemodialysis. However the specific patterns and clinical correlates of sexual functioning remain poorly described. The aim of this study was to assess prevalence and correlates of the individual domains of sexual functioning in women treated with hemodialysis. We recruited, into this multinational cross-sectional study, women treated with long-term hemodialysis (Collaborative Working Group on Depression and Sexual dysfunction in Hemodialysis study). Self-reported domains of sexual functioning were assessed by the Female Sexual Function Index, which is routinely administered within the network of dialysis patients followed by the working group...
2017: PloS One
https://www.readbyqxmd.com/read/28632385/fatigue-resistant-bioinspired-composite-from-synergistic-two-dimensional-nanocomponents
#14
Sijie Wan, Qi Zhang, Xiaohang Zhou, Dechang Li, Baohua Ji, Lei Jiang, Qunfeng Cheng
Portable and wearable electronics require much more flexible graphene-based electrode with high fatigue life, which could repeatedly bend, fold, or stretch without sacrificing its mechanical properties and electrical conductivity. Herein, a kind of ultrahigh fatigue resistant graphene-based nanocomposite via tungsten disulfide (WS2) nanosheets is synthesized by introducing a synergistic effect with covalently cross-linking inspired by the orderly layered structure and abundant interfacial interactions of nacre...
June 22, 2017: ACS Nano
https://www.readbyqxmd.com/read/28630920/bioinspired-shape-memory-graphene-film-with-tunable-wettability
#15
Jie Wang, Lingyu Sun, Minhan Zou, Wei Gao, Cihui Liu, Luoran Shang, Zhongze Gu, Yuanjin Zhao
Functional materials with specific surface wettability play an important role in a wide variety of areas. Inspired by nature's Nepenthes pitcher plant, we present a novel slippery film with tunable wettability based on a shape-memory graphene sponge. The porous graphene sponge coated with shape-memory polymer was used to lock in inert lubricants and construct slippery surfaces to repel different liquids. The superelasticity and high strength, together with good electrical conductivity, of the graphene sponge imparted the graphene/polymer hybrid films with fast recoverable shape-memory properties...
June 2017: Science Advances
https://www.readbyqxmd.com/read/28630790/rehabilitation-of-eyelid-malpositions-secondary-to-facial-palsy
#16
Şeyda Karadeniz Uğurlu, Mustafa Karakaş
OBJECTIVES: To evaluate patient satisfaction and outcomes of surgical treatment of eyelid malpositions secondary to facial palsy. MATERIALS AND METHODS: Consecutive patients with facial palsy who underwent surgical treatment by the same surgeon at İzmir Katip Çelebi University Atatürk Training and Research Hospital between Jan 2007 and Dec 2012 were included in the study. Ophthalmic examination findings, surgical approaches, and their outcomes were evaluated...
June 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28629216/amphiphilic-antifogging-anti-icing-coatings-containing-poss-pdmaema-b-psbma
#17
Chuan Li, Xiaohui Li, Chao Tao, Lixia Ren, Yunhui Zhao, Shan Bai, Xiaoyan Yuan
Highly transparent antifogging/anti-icing coatings were developed from amphiphilic block copolymers of polyhedral oligomeric silsesquioxane-poly[2-(dimethylamino)ethyl methacrylate]-block-poly(sulfobetaine methacrylate) (POSS-PDMAEMA-b-PSBMA) with a small amount of ethylene glycol dimethacrylate (EGDMA) via UV-curing. The excellent antifogging properties of the prepared coatings were originated from the hygroscopicity of both PDMAEMA and PSBMA blocks in the semi-interpenetrating polymer network (SIPN) with polymerization of EGDMA, and the hydrophobic POSS aggregated on the surface...
June 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28628848/sexual-dysfunction-in-infertile-women-a-systematic-review-and-meta-analysis
#18
REVIEW
Carolina R de Mendonça, Jalsi T Arruda, Matias Noll, Paulo M de O Campoli, Waldemar N do Amaral
OBJECTIVE: This study aimed to assess the prevalence of sexual dysfunction and Female Sexual Function Index (FSFI) score in women with infertility. STUDY DESIGN: A systematic search of the literature was conducted using PubMed, EMBASE, IBECS, and LILACS. The search was limited to articles published from January 2000 to September 2016, without language restriction. Data were analyzed using Stata 12.0. Random effects meta-analyses in weighted mean difference (WMD) were performed for six comparative studies (infertility versus fertility)...
June 7, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28626562/shining-a-light-on-transition-metal-chalcogenides-for-sustainable-photovoltaics
#19
Peter D Matthews, Paul D McNaughter, David J Lewis, Paul O'Brien
Transition metal chalcogenides are an important family of materials that have received significant interest in recent years as they have the potential for diverse applications ranging from use in electronics to industrial lubricants. One of their most exciting properties is the ability to generate electricity from incident light. In this perspective we will summarise and highlight the key results and challenges in this area and explain how transition metal chalcogenides are a good choice for future sustainable photovoltaics...
June 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28626139/synthesis-of-ricinoleic-acid-estolides-by-the-esterification-of-ricinoleic-acids-using-functional-acid-ionic-liquids-as-catalysts
#20
Gaoshang Wang, Shangde Sun
Estolides of ricinoleic acid (RA) have been used as lubricants and pigment dispersant in many industries. In this paper, functional acid ionic liquids (ILs) were firstly used as catalysts to prepare RA estolides by the esterification of RAs in solvent-free system. Different ILs were used as catalysts for the esterification. Effect of reaction variables (IL amount, reaction temperature and reaction time) on the esterification were also investigated and optimized using response surface methodology (RSM). Among all tested ILs, [BSO3HMIM]TS showed the best performance for the esterification...
June 13, 2017: Journal of Oleo Science
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