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https://www.readbyqxmd.com/read/28231679/-use-the-markov-decision-tree-model-to-optimize-vaccination-strategies-of-hepatitis-e-among-women-aged-15-to-49
#1
Z M Chen, S B Ji, X L Shi, Y Y Zhao, X F Zhang, H Jin
Objective: To evaluate the cost-utility of different hepatitis E vaccination strategies in women aged 15 to 49. Methods: The Markov-decision tree model was constructed to evaluate the cost-utility of three hepatitis E virus vaccination strategies. Parameters of the models were estimated on the basis of published studies and experience of experts. Both methods on sensitivity and threshold analysis were used to evaluate the uncertainties of the model. Results: Compared with non-vaccination group, strategy on post-screening vaccination with rate as 100%, could save 0...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28230458/progression-to-type-2-diabetes-and-its-effect-on-health-care-costs-in-low-income-and-insured-patients-with-prediabetes-a-retrospective-study-using-medicaid-claims-data
#2
Jun Wu, Eileen Ward, Tiffaney Threatt, Z Kevin Lu
BACKGROUND: Prediabetes is a high-risk factor for progression to diabetes. Without lifestyle changes, such as weight loss and moderate physical activity, 15%-30% of people with prediabetes are projected to develop type 2 diabetes within 5 years. Progression to diabetes increases the financial burden significantly for patients and health care systems. Populations with low socioeconomic status are associated with a higher risk of diabetes. However, knowledge is limited about the effect of transition to diabetes on future costs incurred in low-income populations...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230446/economic-impact-of-treatment-duration-and-persistence-with-basal-insulin-in-previously-insulin-naive-users
#3
Samaneh Kalirai, Ran Duan, Dongju Liu, Beverly L Reed
BACKGROUND: Although insulin is a well-established therapy that is associated with improved clinical outcomes, adherence and persistence with insulin regimens are poor in patients with type 2 diabetes mellitus (T2DM). Diabetes-related health care costs and the impact of insulin persistence patterns on these health care costs have been previously studied; however, these aspects of insulin therapy have limited data beyond the first year of use and have not been characterized among patients previously naive to basal insulin...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28228141/factors-associated-with-contraceptive-use-in-tigray-north-ethiopia
#4
Araya Abrha Medhanyie, Alem Desta, Mussie Alemayehu, Tesfay Gebrehiwot, Tesfu Alemu Abraha, Atakelti Abrha, Hagos Godefay
BACKGROUND: Family planning interventions are cost-effective and have several cross-cutting benefits. Despite these benefits of family planning, progress in ensuring universal access to family planning to women in developing countries has been slow. In light of this; this study investigated the prevalence and factors associated with contraceptive use in Tigray Region, Northern Ethiopia. METHODS: A community-based cross-sectional study was conducted among 1966 women of reproductive age group (15-49) in 13 districts (3 urban and 10 rural) from May-June 2015...
February 23, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28227176/a-novel-method-to-assess-angle-sensor-performance-for-wearable-exoskeletal-joint-kinematics
#5
Nicholas B Bolus, Geza F Kogler, Omer T Inan, Nicholas B Bolus, Geza F Kogler, Omer T Inan, Geza F Kogler, Omer T Inan, Nicholas B Bolus
Full range of motion (ROM) at a joint is necessary for efficient and adaptive movement; as such, it is an essential clinical evaluation measure for assessing an individual's motor function, which can be affected by any number of musculoskeletal injuries and neuropathies. Measurement of joint ROM in the clinic has classically been accomplished statically through the use of a manual goniometer. More recent efforts in the fields of prosthetics and orthotics have demonstrated the potential utility of wearable systems (e...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227156/a-case-study-for-integrated-stem-outreach-in-an-urban-setting-using-a-do-it-yourself-vertical-jump-measurement-platform
#6
John F Drazan, Heather Danielsen, Matthew Vercelletto, Amy Loya, James Davis, Ron Eglash, John F Drazan, Heather Danielsen, Matthew Vercelletto, Amy Loya, James Davis, Ron Eglash, Heather Danielsen, Ron Eglash, John F Drazan, Matthew Vercelletto, Amy Loya, James Davis
The purpose of this study was to develop and deploy a low cost vertical jump platform using readily available materials for Science, Technology, Engineering, and Mathematics (STEM) education and outreach in the inner city. The platform was used to measure the jumping ability of participants to introduce students to the collection and analysis of scientific data in an engaging, accessible manner. This system was designed and fabricated by a student team of engineers as part of a socially informed engineering and design class...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226943/using-liquid-metal-alloy-egain-to-electrochemically-enhance-ss-stimulation-electrodes-for-biobotic-applications
#7
Tahmid Latif, Fengyuan Gong, Michael Dickey, Mihail Sichitiu, Alper Bozkurt, Tahmid Latif, Fengyuan Gong, Michael Dickey, Mihail Sichitiu, Alper Bozkurt, Michael Dickey, Tahmid Latif, Fengyuan Gong, Alper Bozkurt, Mihail Sichitiu
Biobotics is an emerging and useful advent in the field of robotics which harnesses the mechanical power of live invertebrates and benefits from them as "working" animals. Most biobotic applications rely on neural or muscular stimulation through implanted electrodes for achieving direct control of their locomotory behavior. Degradation of stimulation efficiency is often noticed through extended usage, partly owing to incompatibility of implanted electrodes to the application. Our previous achievements in biobotics utilized commercially available stainless steel wires as stimulation electrodes due to its availability and lower cost...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224191/predicting-the-post-operative-length-of-stay-for-the-orthopaedic-trauma-patient
#8
Deepak Chona, Nikita Lakomkin, Catherine Bulka, Idine Mousavi, Parth Kothari, Ashley C Dodd, Michelle S Shen, William T Obremskey, Manish K Sethi
PURPOSE: Length of stay (LOS) is a major driver of cost and quality of care. A bundled payment system makes it essential for orthopaedic surgeons to understand factors that increase a patient's LOS. Yet, minimal data regarding predictors of LOS currently exist. Using the ACS-NSQIP database, this is the first study to identify risk factors for increased LOS for orthopaedic trauma patients and create a personalized LOS calculator. METHODS: All orthopaedic trauma surgery between 2006 and 2013 were identified from the ACS-NSQIP database using CPT codes...
February 21, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28223945/toward-respiratory-assessment-using-depth-measurements-from-a-time-of-flight-sensor
#9
Charles Sharp, Vahid Soleimani, Sion Hannuna, Massimo Camplani, Dima Damen, Jason Viner, Majid Mirmehdi, James W Dodd
Introduction: There is increasing interest in technologies that may enable remote monitoring of respiratory disease. Traditional methods for assessing respiratory function such as spirometry can be expensive and require specialist training to perform and interpret. Remote, non-contact tracking of chest wall movement has been explored in the past using structured light, accelerometers and impedance pneumography, but these have often been costly and clinical utility remains to be defined. We present data from a 3-Dimensional time-of-flight camera (found in gaming consoles) used to estimate chest volume during routine spirometry maneuvres...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28223876/evaluation-of-the-impact-of-a-prescribing-guideline-on-the-use-of-intraoperative-dexmedetomidine-at-a-tertiary-academic-medical-center
#10
Abdullah M Alhammad, Nour A Baghdady, Rachel A Mullin, Bonnie C Greenwood
Objective: To evaluate usage patterns of dexmedetomidine in the operating room after implementation of a prescribing guideline. Methods: We conducted a retrospective analysis to evaluate the impact of a prescribing guideline on usage patterns of dexmedetomidine in the operating room at a tertiary, academic medical center during one-month period pre- (July 2010) and post-guideline (July 2011 and July 2012) implementation. Results: A total of 267 patients received intraoperative dexmedetomidine during the study period...
January 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28223720/is-endoscopic-ultrasound-examination-necessary-in-the-management-of-esophageal-cancer
#11
REVIEW
Tomas DaVee, Jaffer A Ajani, Jeffrey H Lee
Despite substantial efforts at early diagnosis, accurate staging and advanced treatments, esophageal cancer (EC) continues to be an ominous disease worldwide. Risk factors for esophageal carcinomas include obesity, gastroesophageal reflux disease, hard-alcohol use and tobacco smoking. Five-year survival rates have improved from 5% to 20% since the 1970s, the result of advances in diagnostic staging and treatment. As the most sensitive test for locoregional staging of EC, endoscopic ultrasound (EUS) influences the development of an optimal oncologic treatment plan for a significant minority of patients with early cancers, which appropriately balances the risks and benefits of surgery, chemotherapy and radiation...
February 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28223460/mechanism-of-h2s-oxidation-by-the-dissimilatory-perchlorate-reducing-microorganism-azospira-suillum-ps
#12
Misha G Mehta-Kolte, Dana Loutey, Ouwei Wang, Matthew D Youngblut, Christopher G Hubbard, Kelly M Wetmore, Mark E Conrad, John D Coates
The genetic and biochemical basis of perchlorate-dependent H2S oxidation (PSOX) was investigated in the dissimilatory perchlorate-reducing microorganism (DPRM) Azospira suillum PS (PS). Previously, it was shown that all known DPRMs innately oxidize H2S, producing elemental sulfur (S(o)). Although the process involving PSOX is thermodynamically favorable (ΔG°' = -206 kJ ⋅ mol(-1) H2S), the underlying biochemical and genetic mechanisms are currently unknown. Interestingly, H2S is preferentially utilized over physiological electron donors such as lactate or acetate although no growth benefit is obtained from the metabolism...
February 21, 2017: MBio
https://www.readbyqxmd.com/read/28222676/meta-analysis-of-the-utility-of-culture-biopsy-and-direct-koh-examination-for-the-diagnosis-of-onychomycosis
#13
Verónica Velasquez-Agudelo, Jaiberth Antonio Cardona-Arias
BACKGROUND: Onychomycosis is a highly prevalent disease worldwide. There is no standard test for its diagnosis, which remains costly, wasteful, and is sometimes delayed. The diagnostic tests for this disease are few and discordant. The objective was to evaluate the diagnostic validity, performance, and accuracy of culture, nail clipping with Periodic Acid-Schiff -PAS- staining (biopsy), and direct potassium hydroxide (KOH) examination for the study of onychomycosis. METHODS: A systematic review was conducted via meta-analysis using 5 databases and 21 search strategies...
February 22, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28220219/-the-way-from-cost-approval-to-bariatric-surgery-analysis-of-resource-utilization-in-a%C3%A2-maximum-care-hospital
#14
F Nickel, C Tapking, U Zech, K Huennemeyer, A T Billeter, P C Müller, H G Kenngott, B P Müller-Stich, L Fischer
BACKGROUND: Morbid obesity is a medical and economic challenge. Patients who have the indications for bariatric surgery face a long way from the first visit until surgery and a high utilization of resources is required. OBJECTIVES: The present study aimed to evaluate labor costs and labor time required to supervise obese patients from their first visit until preparation of a bariatric report to ask for cost acceptance of bariatric surgery from their health insurance...
February 20, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/28220139/genome-wide-single-nucleotide-polymorphism-discovery-and-the-construction-of-a-high-density-genetic-map-for-melon-cucumis-melo-l-using-genotyping-by-sequencing
#15
Che-Wei Chang, Yu-Hua Wang, Chih-Wei Tung
Although genotyping-by-sequencing (GBS) enables the efficient and low-cost generation of large numbers of markers, the utility of resultant genotypes are limited, because they are enormously error-prone and contain high proportions of missing data. In this study, we generated single nucleotide polymorphism (SNP) markers for 109 recombinant inbred lines of melon (Cucumis melo L.) using the GBS approach and ordered them according to their physical position on the draft double haploid line DHL92 genome. Next, by investigating associations between these SNPs, we discovered that some segments on the physical map conflict with linkage relationships...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28219447/medialization-thyroplasty-versus-injection-laryngoplasty-a-cost-minimization-analysis
#16
Samantha Tam, Hongmei Sun, Sisira Sarma, Jennifer Siu, Kevin Fung, Leigh Sowerby
BACKGROUND: Medialization thyroplasty and injection laryngoplasty are widely accepted treatment options for unilateral vocal fold paralysis. Although both procedures result in similar clinical outcomes, little is known about the corresponding medical care costs. Medialization thyroplasty requires expensive operating room resources while injection laryngoplasty utilizes outpatient resources but may require repeated procedures. The purpose of this study, therefore, is to quantify the cost differences in adult patients with unilateral vocal fold paralysis undergoing medialization thyroplasty versus injection laryngoplasty...
February 20, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28219377/the-effect-of-increasing-the-coinsurance-rate-on-outpatient-utilization-of-healthcare-services-in-south-korea
#17
Hyo Jung Lee, Sung-In Jang, Eun-Cheol Park
BACKGROUND: The Korean healthcare system is composed of costly and inefficient structures that fail to adequately divide the functions and roles of medical care organizations. To resolve this matter, the government reformed the cost-sharing policy in November of 2011 for the management of outpatients visiting general or tertiary hospitals with comparatively mild diseases. The purpose of the present study was to examine the impact of increasing the coinsurance rate of prescription drug costs for 52 mild diseases at general or tertiary hospitals on outpatient healthcare service utilization...
February 20, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28219322/a-screening-program-to-test-and-treat-for-helicobacter-pylori-infection-cost-utility-analysis-by-age-sex-and-ethnicity
#18
Andrea M Teng, Giorgi Kvizhinadze, Nisha Nair, Melissa McLeod, Nick Wilson, Tony Blakely
BACKGROUND: The World Health Organization recommends all countries consider screening for H. pylori to prevent gastric cancer. We therefore aimed to estimate the cost-effectiveness of a H. pylori serology-based screening program in New Zealand, a country that includes population groups with relatively high gastric cancer rates. METHODS: A Markov model was developed using life-tables and morbidity data from a national burden of disease study. The modelled screening program reduced the incidence of non-cardia gastric cancer attributable to H...
February 20, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28216180/utility-of-16s-rrna-pcr-performed-on-clinical-specimens-in-patient-management
#19
A Akram, M Maley, I Gosbell, T Nguyen, R Chavada
BACKGROUND: Broad range PCR 16S rRNA can be used for detection and identification of bacteria from clinical specimens in patients with high suspicion of infection and negative cultures. Aim of this study was 1) to compare 16S rRNA PCR (16S) results with microbiological cultures 2) to assess utility of 16S on antimicrobial therapy 3) to compare the yield of 16S on different type of clinical specimen and cost analysis of test. METHODS: A retrospective study was done on different clinical specimens which had 16S performed over 3 years (2012-2015)...
February 16, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28215794/the-spatiotemporal-variation-analysis-of-virtual-water-for-agriculture-and-livestock-husbandry-a-study-for-jilin-province-in-china
#20
Xiaolei Ma, Yanji Ma
With the rapid development of economic, water crisis is becoming more and more serious and would be an important obstacle to the sustainable development of society. Virtual water theory and its applications in agriculture can provide important strategies for realizing the reasonable utilization and sustainable development of water resources. Using the Penman-Monteith model and Theil index combining the CROPWAT software, this work takes Jilin Province as study area quantifying the virtual water content of agriculture and livestock husbandry and giving a comprehensive evaluation of their spatiotemporal structure evolution...
February 16, 2017: Science of the Total Environment
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