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Cost utility analysis

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https://www.readbyqxmd.com/read/29054509/the-cost-effectiveness-of-salpingectomies-for-family-planning-in-the-prevention-of-ovarian-cancer
#1
R W Melissa Tai, Stephanie K Y Choi, Peter C Coyte
OBJECTIVE: Ovarian cancer is the most lethal gynaecologic cancer. Disease prevention may be the only method to reduce the incidence of ovarian cancer. The Society of Gynecologic Oncology advised that salpingectomies may be an appropriate and feasible strategy for ovarian cancer risk reduction. This study conducted an economic evaluation from a societal perspective of bilateral salpingectomies versus conventional sterilization techniques in the prevention of ovarian cancer. STUDY DESIGN: We performed a micro-cost analysis comparing laparoscopic tubal coagulation, tubal clips and bilateral salpingectomies at the Michael Garron Hospital, formerly the Toronto East General Hospital, from 2015 to 2016...
October 17, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29054492/a-cost-analysis-of-an-interdisciplinary-pediatric-chronic-pain-clinic
#2
Nicole E Mahrer, Jeffrey I Gold, Michael Luu, Patricia Herman
Chronic pain is characterized by high rates of functional impairment, healthcare utilization, and associated costs. Research supports the use of comprehensive, interdisciplinary treatment approaches. However, many hospitals hesitate to offer this full range of services, especially to Medi-Cal/Medicaid patients whose services are reimbursed at low rates. This cost analysis examines the impact on hospital and insurance costs of patients' enrollment in an interdisciplinary pediatric pain clinic, which includes medication management, psychotherapy, biofeedback, acupuncture, and massage...
October 17, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29053610/lab-on-chip-surface-enhanced-raman-analysis-by-aerosol-jet-printing-and-roll-to-roll-hot-embossing
#3
Anne Habermehl, Noah Strobel, Ralph Eckstein, Nico Bolse, Adrian Mertens, Gerardo Hernandez-Sosa, Carsten Eschenbaum, Uli Lemmer
Surface-enhanced Raman spectroscopy (SERS) combines the high specificity of Raman scattering with high sensitivity due to an enhancement of the electromagnetic field by metallic nanostructures. However, the tyical fabrication methods of SERS substrates suffer from low throughput and therefore high costs. Furthermore, point-of-care applications require the investigation of liquid solutions and thus the integration of the SERS substrate in a microfluidic chip. We present a roll-to-roll fabrication approach for microfluidics with integrated, highly efficient, surface-enhanced Raman scattering structures...
October 20, 2017: Sensors
https://www.readbyqxmd.com/read/29051519/from-porous-to-dense-nanostructured-%C3%AE-ti-alloys-through-high-pressure-torsion
#4
Conrado R M Afonso, Angelica Amigó, Vladimir Stolyarov, Dmitri Gunderov, Vicente Amigó
β-Ti alloys have low elastic modulus, good specific strength and high corrosion resistance for biomaterial applications. Noble elements, such as Nb, Ta and Mo, are used to obtain β-Ti due to their chemical biocompatibility. However, due to their refractory nature, β-Ti requires specific processing routes. Powder metallurgy (P/M) allows for the development of new β-Ti alloys with decreasing costs, but dealing with high-elemental-content alloys can lead to a lack of diffusion and grain growth. One method to refine the structure and improve mechanical properties is a severe plastic deformation technique through high-pressure torsion (HPT)...
October 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29051143/health-care-costs-associated-with-aki
#5
David Collister, Neesh Pannu, Feng Ye, Matthew James, Brenda Hemmelgarn, Betty Chui, Braden Manns, Scott Klarenbach
BACKGROUND AND OBJECTIVES: An understanding of the health care resource use associated with AKI is needed to frame the investment and cost-effectiveness of strategies to prevent AKI and promote kidney recovery. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We assembled population-based cohort of adults hospitalized in Alberta between November of 2002 and March of 2009 without ESRD or an eGFR<15 ml/min per 1.73 m(2). Outpatient serum creatinine measurements 6 months preceding admission defined baseline kidney function, and serum creatinine during the first 14 days of hospitalization defined Acute Kidney Injury Network stage; kidney recovery defined as serum creatinine within 25% of baseline and independence from dialysis was assessed at 90 days after AKI...
October 19, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29050629/nationwide-trends-in-hospital-outcomes%C3%A2-and-utilization-after-lower%C3%A2-limb-revascularization-in-patients%C3%A2-on-hemodialysis
#6
Pranav S Garimella, Poojitha Balakrishnan, Ashish Correa, Priti Poojary, Narender Annapureddy, Kinsuk Chauhan, Achint Patel, Shanti Patel, Ioannis Konstantinidis, Lili Chan, Shiv Kumar Agarwal, Bernard G Jaar, Umesh Gidwani, Kunihiro Matsushita, Girish N Nadkarni
OBJECTIVES: This study aimed to describe the temporal trends and outcomes of endovascular and surgical revascularization in a large, nationally representative sample of patients with end-stage renal disease on hemodialysis hospitalized for peripheral artery disease (PAD). BACKGROUND: PAD is prevalent among patients with end-stage renal disease on hemodialysis and is associated with significant morbidity and mortality. There is a paucity of information on trends in endovascular and surgical revascularization and post-procedure outcomes in this population...
October 23, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29050352/ras-testing-and-cetuximab-treatment-for-metastatic-colorectal-cancer-a-cost-effectiveness-analysis-in-a-setting-with-limited-health-resources
#7
Bin Wu, Yuan Yao, Ke Zhang, Xuezhen Ma
PURPOSE: To test the cost-effectiveness of cetuximab plus irinotecan, fluorouracil, and leucovorin (FOLFIRI) as first-line treatment in patients with metastatic colorectal cancer (mCRC) from a Chinese medical insurance perspective. RESULTS: Baseline analysis showed that the addition of cetuximab increased quality-adjusted life-years (QALYs) by 0.63, an increase of $17,086 relative to FOLFIRI chemotherapy, resulting in an incremental cost-effectiveness ratio (ICER) of $27,145/QALY...
September 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29049131/comparison-of-surgical-outcomes-narcotics-utilization-and-costs-after-an-anterior-cervical-discectomy-and-fusion-stand-alone-cage-versus-anterior-plating
#8
Ehsan Tabaraee, Junyoung Ahn, Daniel D Bohl, Michael J Collins, Dustin H Massel, Khaled Aboushaala, Kern Singh
STUDY DESIGN: Retrospective cohort analysis of a prospectively maintained registry. OBJECTIVE: To compare the surgical outcomes, narcotic utilization, and costs between a stand-alone (SA) cage and anterior plating (AP) with an interbody device for 1-level anterior cervical discectomy and fusion (ACDF). BACKGROUND DATA: ACDF with a SA cage has gained popularity as a potential alternative to anterior cervical plating. Few studies have compared the surgical outcomes, narcotic utilization, and costs of ACDF utilizing a SA cage versus AP with an interbody device...
November 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29049052/a-cost-utility-analysis-of-nonsurgical-treatments-for-stress-urinary-incontinence-in-women
#9
Andrea N Simpson, Alaina Garbens, Fahima Dossa, Peter C Coyte, Nancy N Baxter, Colleen D McDermott
OBJECTIVE: The objective of this study was to perform a cost-utility analysis of nonsurgical treatments for stress urinary incontinence (SUI) in healthy adult women with a health system perspective over a 1-year time horizon. METHODS: A decision tree model was constructed to evaluate the following nonsurgical treatment options for SUI in a simulated healthy adult female cohort who had failed Kegel exercises: pelvic floor muscle therapy (PFMT), a disposable tampon device (Impressa), a self-fitting intravaginal incontinence device (Uresta), and a traditional incontinence pessary...
October 18, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29046384/temperate-marine-protected-area-provides-recruitment-subsidies-to-local-fisheries
#10
A Le Port, J C Montgomery, A N H Smith, A E Croucher, I M McLeod, S D Lavery
The utility of marine protected areas (MPAs) as a means of protecting exploited species and conserving biodiversity within MPA boundaries is supported by strong empirical evidence. However, the potential contribution of MPAs to fished populations beyond their boundaries is still highly controversial; empirical measures are scarce and modelling studies have produced a range of predictions, including both positive and negative effects. Using a combination of genetic parentage and relatedness analysis, we measured larval subsidies to local fisheries replenishment for Australasian snapper (Chrysophrys auratus: Sparidae) from a small (5...
October 25, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29044739/peripheral-intravenous-cannula-insertion-and-use-in-the-emergency-department-an-intervention-study
#11
Tracey Hawkins, Jaimi H Greenslade, Jessica Suna, Julian Williams, Matthew Jensen, Maria Donohue, Elizabeth Ho, Christopher Van Hise, Diana Egerton-Warburton, Louise Cullen
OBJECTIVES: To examine cannulation practice and effectiveness of a multi-modal intervention to reduce peripheral intravenous cannula (PIVC) insertion in emergency department (ED) patients. METHODS: A prospective before and after study and cost analysis was conducted at a single tertiary ED in Australia. Data were collected 24 hours a day for two weeks pre- and post-implementation of a multi-modal intervention. PIVC placement and utilization within 24 hours were evaluated in all eligible patients...
October 16, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29043922/barriers-and-facilitators-to-dispensing-of-intranasal-naloxone-by-pharmacists
#12
Ludmila N Bakhireva, Adriana Bautista, Sandra Cano, Shikhar Shrestha, Amy M Bachyrycz, Theresa H Cruz
BACKGROUND: While misuse of prescription opioids has reached epidemic proportions, pharmacy-based preventive services to combat this epidemic are limited. The aims of this study were to identify barriers and facilitators to the dispensing of intranasal naloxone (INN) by pharmacists in New Mexico. METHODS: For this mixed methods study, a qualitative component (focus group) informed the development of a quantitative component (electronic survey) distributed to all pharmacists registered with the New Mexico Board of Pharmacy and practicing in the state...
October 18, 2017: Substance Abuse
https://www.readbyqxmd.com/read/29043567/impact-of-adverse-events-on-health-utility-and-health-related-quality-of-life-in-patients-receiving-first-line-chemotherapy-for-metastatic-breast-cancer-results-from-the-select-bc-study
#13
Yasuhiro Hagiwara, Takeru Shiroiwa, Kojiro Shimozuma, Takuya Kawahara, Yukari Uemura, Takanori Watanabe, Naruto Taira, Takashi Fukuda, Yasuo Ohashi, Hirofumi Mukai
OBJECTIVE: The aim of this study was to investigate the impact of adverse events (AEs) on health utility and health-related quality of life (HRQOL) in patients with metastatic breast cancer undergoing first-line chemotherapy. METHODS: We analyzed the data from the SELECT BC study, a multicenter, open-label, randomized, phase III study conducted in Japan, which compared first-line S-1 with taxane therapies. Heath utility and HRQOL were assessed using the EQ-5D-3L and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) at baseline and 3, 6, and 12 months after treatment initiation...
October 17, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/29042340/mental-and-emotional-self-help-technology-apps-cross-sectional-study-of-theory-technology-and-mental-health-behaviors
#14
Benjamin T Crookston, Joshua H West, P Cougar Hall, Kaitana Martinez Dahle, Thomas L Heaton, Robin N Beck, Chandni Muralidharan
BACKGROUND: Mental and emotional self-help apps have emerged as potential mental illness prevention and treatment tools. The health behavior theory mechanisms by which these apps influence mental health-related behavior change have not been thoroughly examined. OBJECTIVE: The objective of this study was to examine the association between theoretical behavior change mechanisms and use of mental and emotional self-help apps and whether the use of such apps is associated with mental health behaviors...
October 17, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/29041909/cost-utility-analysis-of-palivizumab-for-respiratory-syncytial-virus-infection-prophylaxis-in-preterm-infants-update-based-on-the-clinical-evidence-in-spain
#15
M Sanchez-Luna, R Burgos-Pol, I Oyagüez, J Figueras-Aloy, M Sánchez-Solís, F Martinón-Torres, X Carbonell-Estrany
BACKGROUND: This study aimed at estimating the efficiency of palivizumab in the prevention of Respiratory Syncytial Virus (RSV) infection and its sequelae in preterm infants (32(day 1)-35(day 0)weeks of gestational age -wGA-) in Spain. METHODS: A decision-tree model was developed to compare health benefits (Quality Adjusted Life Years-QALYs) and costs of palivizumab versus a non-prophylaxis strategy over 6 years. A hypothetical cohort of 1,000 preterm infants, 32(day 1)-35(day 0) wGA (4...
October 17, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29040127/double-row-arthroscopic-rotator-cuff-repair-is-more-cost-effective-than-single-row-repair
#16
Adrian L Huang, Kednapa Thavorn, Sasha van Katwyk, Peter MacDonald, Peter Lapner
BACKGROUND: The optimal technique for arthroscopic rotator cuff repair is controversial, and both single and double-row techniques are commonly used. In the current era of increasing costs, health-care delivery models are focusing on the value of care. In this study, we compared the cost-effectiveness of single-row and double-row reconstructions in patients undergoing arthroscopic rotator cuff repair. METHODS: A cost-utility analysis was performed from the perspective of a publicly funded health-care system...
October 18, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29039976/challenges-and-recommendations-for-the-health-economic-evaluation-of-primary-prevention-programmes-for-dementia
#17
Ron Handels, Anders Wimo
OBJECTIVE: We aimed to review health-economic evaluations of (hypothetical) intervention programmes for the primary prevention of dementia, and highlight challenges and provide recommendations for future research to estimate its cost-effectiveness. METHODS: We searched the databases PubMed, MODEM, CEA and NHS for publications on the cost-consequence, -effectiveness, -utility or -benefit analysis of (hypothetical) interventions to reduce the risk of developing dementia for persons without dementia, and described the study characteristics...
October 17, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/29037172/the-impact-of-influenza-on-the-health-related-quality-of-life-in-china-an-eq-5d-survey
#18
Juan Yang, Mark Jit, Yaming Zheng, Luzhao Feng, Xinxin Liu, Joseph T Wu, Hongjie Yu
BACKGROUND: Influenza causes considerable morbidity and mortality in China, but its impact on the health-related quality of life (HRQoL) has not been previously measured. METHODS: We conducted a retrospective telephone survey to assess the impact of influenza on the HRQoL among outpatients and inpatients using the EuroQoL EQ-5D-3 L instrument. Participants were individuals with laboratory-confirmed influenza infection registered by the National Influenza-like-illness Surveillance Network in 2013...
October 16, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29036629/nanotechnology-a-promising-new-paradigm-for-the-control-of-pain
#19
Krishnan V Chakravarthy, Frank J Boehm, Paul J Christo
Objective: The objective of this article is to critically review both preclinical and clinical studies that focus on the use of nanotechnology for both acute and chronic pain management, surveying both diagnostic and therapeutic applications. The article also provides information on nanotechnology for pain practitioners, so that they may better understand how this technology works and how it may be applied to their day-to-day clinical practice. Study Design: Narrative review...
June 27, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29036249/cost-effectiveness-analysis-of-ixekizumab-vs-etanercept-and-their-manufacturer-recommended-dosing-regimens-in-moderate-to-severe-plaque-psoriasis
#20
Jeremy Udkoff, Lawrence F Eichenfield
INTRODUCTION: Biologic therapies have revolutionized the treatment of psoriasis; however, their use is limited by costs. Ixekizumab was more effective than etanercept in the UNCOVER trials, and the Food and Drug Administration (FDA) approved ixekizumab for treating psoriasis. Evaluating the cost-effectiveness of these therapies is crucial for medical decision making and our objective was to determine the cost-effectiveness of various ixekizumab dosing frequencies compared with etanercept...
October 1, 2017: Journal of Drugs in Dermatology: JDD
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