Lance Kuo-Esser, Ramon Chen, Kylie Lawson, Kennedy Kuchinski, Nijah Simmons, Mauricio Dominguez, Tommy Scandura, Martin Vo, Emma Dasenbrock-Gammon, Natalie Hagan, Haley Esposito, Molly Thompson, Steven Le, Wilber Escorcia, Hanna N Wetzel
Caffeine, a widely consumed stimulant, is known for its effects on alertness and fatigue reduction by blockade of adenosine receptors. While it holds therapeutic potential, its diverse impacts pose risks, particularly in early development. This study explores the developmental effects of caffeine exposure using Caenorhabditis elegans (C. elegans) as a model organism. We investigated morphological and behavioral changes induced by caffeine exposure at the L1 stage and assessed their impact at the L4 stage, which roughly corresponds to human infancy and adolescence, respectively...
November 14, 2023: Biochemical and Biophysical Research Communications