S100B in children after anesthesia

BACKGROUND: The current management guidelines for pediatric mild head injury (MHI) liberally recommend computed tomography (CT) and frequent admission. Serum protein S100B, currently used in management of adult head injury, has recently shown potential for reducing unnecessary CT scans after pediatric mild head injury. Capillary sampling in children is commonly used when venous sampling fails or is inappropriate. We present reference values for both venous and capillary samples of protein S100B in children...

This study aimed to compare the release of S100B and NSE between cardiac surgery and interventional therapy for children and to investigate whether S100B serum concentration correlates with cardiopulmonary bypass in children. For this study, 40 children with congenital heart disease were selected and assigned to two groups: group A (20 children undergoing surgical therapy) and group B (20 children undergoing interventional therapy). In group A, blood samples were drawn 10 min after the induction of anesthesia, immediately after aortic cross-clamping, immediately at the end of cardiopulmonary bypass (CPB), immediately at the end of the operation, then 6 and 24 h after the operation...