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mathematical model trauma

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https://www.readbyqxmd.com/read/29731951/advanced-computational-methods-in-bio-mechanics
#1
REVIEW
Waleed M S Al Qahtani, Mohamed I El-Anwar
A novel partnership between surgeons and machines, made possible by advances in computing and engineering technology, could overcome many of the limitations of traditional surgery. By extending surgeons' ability to plan and carry out surgical interventions more accurately and with fewer traumas, computer-integrated surgery (CIS) systems could help to improve clinical outcomes and the efficiency of healthcare delivery. CIS systems could have a similar impact on surgery to that long since realised in computer-integrated manufacturing...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29492523/prognosis-of-severe-traumatic-brain-injury-outcomes-in-children
#2
Semen V Meshcheryakov, Zhanna B Semenova, Valery I Lukianov, Elena G Sorokina, Olga V Karaseva
OBJECTIVES: We aimed to determine prognostic factors that can influence the outcome of severe traumatic brain injury (TBI) in children. MATERIALS AND METHODS: One hundred and sixty-nine patients with severe TBI were included. Consciousness was evaluated using the Glasgow Coma Scale (GCS). Severity of concomitant injuries was evaluated using the Injury Severity Score (ISS). Computer tomography (CT) scanning was used on admission and later. Intracranial injuries were classified using the Marshall CT scale...
2018: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/29433071/applying-crash-data-to-injury-claims-an-investigation-of-determinant-factors-in-severe-motor-vehicle-accidents
#3
Darren Shannon, Finbarr Murphy, Martin Mullins, Julian Eggert
An extensive number of research studies have attempted to capture the factors that influence the severity of vehicle impacts. The high number of risks facing all traffic participants has led to a gradual increase in sophisticated data collection schemes linking crash characteristics to subsequent severity measures. This study serves as a departure from previous research by relating injuries suffered in road traffic accidents to expected trauma compensation payouts and deriving a quantitative cost function. Data from the National Highway Traffic Safety Administration's (NHTSA) Crash Injury Research (CIREN) database for the years 2005-2014 is combined with the Book of Quantum, an Irish governmental document that offers guidelines on the appropriate compensation to be awarded for injuries sustained in accidents...
April 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29391111/current-methods-and-advances-in-simulation-of-hemorrhage-after-trauma
#4
Cayley Bowles, Daniel Canuto, Joseph Teran, Erik Dutson, David Plurad, Jeff Eldredge, Peyman Benharash
As animal models fall out of favor, there is demand for simulators to train medical personnel in the management of trauma and hemorrhage. Realism is essential to the development of simulators for training in the management of trauma and hemorrhage, but is difficult to achieve because it is difficult to create models that accurately represent bleeding organs. We present a simulation platform that uses real-time mathematical modeling of hemodynamics after hemorrhage and trauma and visually represents the injury described by the model...
October 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29382857/neuroprotective-drug-for-nerve-trauma-revealed-using-artificial-intelligence
#5
David Romeo-Guitart, Joaquim Forés, Mireia Herrando-Grabulosa, Raquel Valls, Tatiana Leiva-Rodríguez, Elena Galea, Francisco González-Pérez, Xavier Navarro, Valerie Petegnief, Assumpció Bosch, Mireia Coma, José Manuel Mas, Caty Casas
Here we used a systems biology approach and artificial intelligence to identify a neuroprotective agent for the treatment of peripheral nerve root avulsion. Based on accumulated knowledge of the neurodegenerative and neuroprotective processes that occur in motoneurons after root avulsion, we built up protein networks and converted them into mathematical models. Unbiased proteomic data from our preclinical models were used for machine learning algorithms and for restrictions to be imposed on mathematical solutions...
January 30, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29370062/maximizing-geographical-efficiency-an-analysis-of-the-configuration-of-colorado-s-trauma-system
#6
Jan O Jansen, Ernest E Moore, Handing Wang, Jonathan J Morrison, James D Hutchison, Marion K Campbell, Angela Sauaia
BACKGROUND: Trauma center designation in excess of need risks dilution of experience, reduction in research and training opportunities, and increased costs. The objective of this study was to evaluate the use of a novel data-driven approach (whole-system mathematical modelling of patient flow) to compare the configuration of an existing trauma system with a mathematically optimized design, using the State of Colorado as a case study. METHODS: Geographical network analysis and multi-objective optimization...
January 24, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28873828/fuzzy-logic-to-determine-the-likelihood-of-survival-for-trauma-injury-patients
#7
Mohammed Saleh, Reza Saatchi, Fiona Lecky, Derek Burke
A system to determine the likelihood of survival for trauma injury patients is being developed. It uses a fuzzy logic approach that can model complex processes without reliance on sophisticated mathematical formulations and may have the potential to be more accurate than the existing approaches. The outline operation of the system that is currently in a prototype stage is described.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28804267/mathematical-and-computational-modelling-of-skin-biophysics-a-review
#8
REVIEW
Georges Limbert
The objective of this paper is to provide a review on some aspects of the mathematical and computational modelling of skin biophysics, with special focus on constitutive theories based on nonlinear continuum mechanics from elasticity, through anelasticity, including growth, to thermoelasticity. Microstructural and phenomenological approaches combining imaging techniques are also discussed. Finally, recent research applications on skin wrinkles will be presented to highlight the potential of physics-based modelling of skin in tackling global challenges such as ageing of the population and the associated skin degradation, diseases and traumas...
July 2017: Proceedings. Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28685210/lifetime-cost-of-abusive-head-trauma-at-ages-0-4-usa
#9
Ted R Miller, Ryan Steinbeigle, Bruce A Lawrence, Cora Peterson, Curtis Florence, Marilyn Barr, Ronald G Barr
This paper aims to estimate lifetime costs resulting from abusive head trauma (AHT) in the USA and the break-even effectiveness for prevention. A mathematical model incorporated data from Vital Statistics, the Healthcare Cost and Utilization Project Kids' Inpatient Database, and previous studies. Unit costs were derived from published sources. From society's perspective, discounted lifetime cost of an AHT averages $5.7 million (95% CI $3.2-9.2 million) for a death. It averages $2.6 million (95% CI $1.0-2.9 million) for a surviving AHT victim including $224,500 for medical care and related direct costs (2010 USD)...
July 6, 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/28677081/the-role-of-impairment-of-mesenchymal-stem-cell-function-in-osteoporotic-bone-fracture-healing
#10
Lihai Zhang, Saeed Miramini, Martin Richardson, Priyan Mendis, Peter Ebeling
With demographic change and increasing life expectancy, osteoporotic fractures have become one of the most prevalent trauma conditions seen in daily clinical practice. A variety of factors are known to affect the rate of healing in osteoporotic conditions (e.g. both biochemical and biomechanical environment of callus cells). However, the influence of impairment of mesenchymal stem cell function in the osteoporotic condition on bone fracture healing has not been fully understood. In the present study, we develop a mathematical model that quantifies the change in biological processes within the fracture callus as a result of osteoporosis...
September 2017: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/28641984/bi-objective-approach-for-placing-ground-and-air-ambulance-base-and-helipad-locations-in-order-to-optimize-ems-response
#11
REVIEW
Milad Shahriari, Ali Bozorgi-Amiri, Shayan Tavakoli, Abolghasem Yousefi-Babadi
Shortening the travel time of patient transfer has clinical implications for many conditions such as cardiac arrest, trauma, stroke and STEMI. As resources are often limited precise calculations are needed. In this paper we consider the location problem for both ground and aerial emergency medical services. Given the uncertainty of when patients are in need of prompt medical attention we consider these demand points to be uncertain. We consider various ways in which ground and helicopter ambulances can work together to make the whole process go faster...
December 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28395008/derivation-and-validation-of-a-serum-biomarker-panel-to-identify-infants-with-acute-intracranial-hemorrhage
#12
Rachel Pardes Berger, Brian J Pak, Mariya D Kolesnikova, Janet Fromkin, Richard Saladino, Bruce E Herman, Mary Clyde Pierce, David Englert, Paul T Smith, Patrick M Kochanek
Importance: Abusive head trauma is the leading cause of death from physical abuse. Missing the diagnosis of abusive head trauma, particularly in its mild form, is common and contributes to increased morbidity and mortality. Serum biomarkers may have potential as quantitative point-of-care screening tools to alert physicians to the possibility of intracranial hemorrhage. Objective: To identify and validate a set of biomarkers that could be the basis of a multivariable model to identify intracranial hemorrhage in well-appearing infants using the Ziplex System...
June 5, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28238406/the-effect-of-trauma-on-neanderthal-culture-a-mathematical-analysis
#13
W Nakahashi
Traumatic lesions are often observed in ancient skeletal remains. Since ancient medical technology was immature, severely traumatized individuals may have frequently lost the physical ability for cultural skills that demand complex body movements. I develop a mathematical model to analyze the effect of trauma on cultural transmission and apply it to Neanderthal culture using Neanderthal fossil data. I estimate from the data that the proportion of adult individuals who suffered traumatic injuries before death was approximately 0...
February 4, 2017: Homo: Internationale Zeitschrift Für die Vergleichende Forschung Am Menschen
https://www.readbyqxmd.com/read/28224290/pediatric-ocular-trauma-score-as-a-prognostic-tool-in-the-management-of-pediatric-traumatic-cataracts
#14
Mehul A Shah, Rupesh Agrawal, Ryan Teoh, Shreya M Shah, Kashyap Patel, Satyam Gupta, Siddharth Gosai
OBJECTIVE: To introduce and validate the pediatric ocular trauma score (POTS) - a mathematical model to predict visual outcome trauma in children with traumatic cataract METHODS: In this retrospective cohort study, medical records of consecutive children with traumatic cataracts aged 18 and below were retrieved and analysed. Data collected included age, gender, visual acuity, anterior segment and posterior segment findings, nature of surgery, treatment for amblyopia, follow-up, and final outcome was recorded on a precoded data information sheet...
May 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27642666/the-effect-of-piston-diameter-in-stapedotomy-for-otosclerosis-a-temporal-bone-model
#15
Inge Wegner, Mostafa M A S Eldaebes, Thomas G Landry, Wilko Grolman, Manohar L Bance
HYPOTHESIS: The use of larger-diameter pistons in stapedotomy leads to better hearing outcomes compared with the use of smaller-diameter pistons. There is an interaction between stapes piston diameter and fenestration diameter. BACKGROUND: Otosclerosis can be treated surgically by removing part of the stapes and bypassing the stapes footplate with a prosthesis. Available piston shaft diameters range between 0.3 and 0.8 mm. There has been a tendency toward the use of smaller-diameter pistons, because of a suspected decreased risk of cochlear trauma and subsequent sensorineural hearing loss (SNHL) with smaller pistons...
December 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27552712/simple-mathematical-model-of-sacroiliac-screws-safe-zone-easy-to-implement-by-pelvic-inlet-and-outlet-views
#16
Amir Herman, Emily Keener, Candice Dubose, Jason A Lowe
Percutaneous sacral screw fixation is the mainstay of posterior pelvic ring fixation. This study quantifies the accuracy of fluoroscopic screw placement using post-operative CT scans and redefines the fluoroscopic safe zone using a mathematical calculation obtained from Inlet and outlet images. The authors hypothesized that a mathematical calculation of screw placement within the ala will improve accuracy of screw placement. A retrospective review of consecutive patients admitted to a level 1 trauma center with pelvic fractures fixed with iliosacral screws from January 2011 to December 2014 was performed...
July 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27442918/modelling-the-failure-precursor-mechanism-of-lamellar-fibrous-tissues-example-of-the-annulus-fibrosus
#17
Marlène Mengoni, Alison C Jones, Ruth K Wilcox
The aims of this study were to assess the damage and failure strengths of lamellar fibrous tissues, such as the anterior annulus fibrosus (AF), and to develop a mathematical model of damage propagation of the lamellae and inter-lamellar connections. This level of modelling is needed to accurately predict the effect of damage and failure induced by trauma or clinical interventions. 26 ovine anterior AF cuboid specimens from 11 lumbar intervertebral discs were tested in radial tension and mechanical parameters defining damage and failure were extracted from the in-vitro data...
October 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27087777/mathematical-modeling-of-fixation-of-a-bone-fragment-in-a-new-double-needle-external-fixator-compared-to-hoffmann-ii-fixator
#18
M Pitkin, Y Shukeylo, A Gritsanov
The outcome of rehabilitation after multiple bone fractures can be improved, and the reduction of the rate of amputation due to severe trauma can be achieved with the early use of external fixators [1, 2]. Effectiveness of the fixator depends on the stability of the bone fragments during the evacuation of a patient to specialized facilities [3, 4]. The paper is devoted to the mathematical modeling of the stability of a bone fragment in an external fixator. The vertical displacement of the end of a bone fragment loaded with a standardized force and moment is suggested to be the measure of stability...
December 2007: Series on Biomechanics
https://www.readbyqxmd.com/read/26577480/blood-flow-versus-hematocrit-in-optimization-of-oxygen-transfer-to-tissue-during-fluid-resuscitation
#19
Jamal Siam, Marwa Kadan, Ron Flaishon, Ofer Barnea
The effectiveness of fluid resuscitation regimens in hemorrhagic trauma is assessed based on its ability to increase oxygen concentration in tissue. Fluid resuscitation using both crystalloids and colloids fluids, creates a dilemma due to its opposing effects on oxygen transfer. It increases blood flow thereby augmenting oxygen transport but it also dilutes the blood simultaneously and reduces oxygen concentration thereby reducing oxygen transport. In this work we have studied these two opposing effects of fluid therapy on oxygen delivery to tissue...
December 2015: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/26394339/auto-stop-drilling-device-for-implant-site-preparation-in-vitro-test-of-eccentric-sensor-position
#20
Linda Schwarz, Bernhard Pommer, Manfred Bijak, Georg Watzek, Ewald Unger
PURPOSE: To quantify the reliability of a new drilling system for implant osteotomy characterized by an eccentric sensor that automatically stops the drill upon contact with soft tissue. This safety mechanism aims to minimize surgical trauma to nerves, vessels, and the maxillary sinus mucosa. The benefits of the eccentric sensor position on planar and angulated surfaces were tested in vitro. MATERIALS AND METHODS: Predicted drill protrusion after auto-stop was validated against experiments on four human cadaver mandibles (30 osteotomies with varying angles)...
September 2015: International Journal of Oral & Maxillofacial Implants
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