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Cost effectiveness analysis

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https://www.readbyqxmd.com/read/29169104/reconciling-ethical-and-economic-conceptions-of-value-in-health-policy-using-the-capabilities-approach-a-qualitative-investigation-of-non-invasive-prenatal-testing
#1
Mia Kibel, Meredith Vanstone
When evaluating new morally complex health technologies, policy decision-makers consider a broad range of different evaluations, which may include the technology's clinical effectiveness, cost effectiveness, and social or ethical implications. This type of holistic assessment is challenging, because each of these evaluations may be grounded in different and potentially contradictory assumptions about the technology's value. One such technology where evaluations conflict is Non-Invasive Prenatal Testing (NIPT)...
November 16, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29169024/self-cleaning-superhydrophobic-epoxy-coating-based-on-fibrous-silica-coated-iron-oxide-magnetic-nanoparticles
#2
Haleema Alamri, Abdullah Al-Shahrani, Enrico Bovero, Turki Khaldi, Gasan Alabedi, Waleed Obaid, Ihsan Al-Taie, Aziz Fihri
Inspired by the self-cleaning lotus leaf, a facile method of fabricating superhydrophobic silica coated magnetite nanoparticles using a cost-effective process is presented in this work. The structural characterizations and magnetic properties of the obtained core-shell magnetic nanoparticles were characterized by means of X-ray diffraction (XRD), thermal gravimetric analysis (TGA), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and vibrating sample magnetometer (VSM). TEM analysis revealed that the particles present flower-like dendrimeric fibers morphology...
November 15, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29168880/cost-effectiveness-of-a-care-transitions-program-in-a-multimorbid-older-adult-cohort
#3
Gregory J Hanson, Bijan J Borah, James P Moriarty, Jeanine E Ransom, James M Naessens, Paul Y Takahashi
BACKGROUND/OBJECTIVES: Facing penalties for preventable 30-day hospital readmissions, many provider groups have implemented programs to remedy this problem, but the cost efficacy and value of such programs are not well delineated. The objective was to compare total cost of care over 30 days of individuals enrolled in the Mayo Clinic Care Transitions (MCCT) program and individuals not enrolled. DESIGN: Retrospective cohort study using secondary data analysis of a previously published cohort study...
November 23, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29168643/disruptive-therapeutic-innovation-and-the-opportunity-to-eliminate-a-chronic-disease-the-issue-of-chronic-hepatitis-c-in-spain
#4
Conrado M Fernández Rodríguez
Public funding decisions must be guided by criteria of scientific evidence, cost-effectiveness and economic evaluation. As an increase in health-effectiveness provided by therapeutic innovations can also substantially raise the cost, the cost-effectiveness analysis estimating this increase in the cost per unit of health gained compared to the previous technologies should be part of the economic evaluation. The measure of effectiveness most frequently used in health economic evaluations is the Quality Adjusted Life Year (QALY)...
November 23, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29168641/economic-evaluation-of-endoscopic-radiofrequency-ablation-for-the-treatment-of-dysplastic-barrett-s-esophagus-in-spain
#5
José-Miguel Esteban, Pedro González-Carro, Joan B Gornals, Carlos Collados, María Álvarez, Alejandro Pérez-Mitru, Suzan Serip
BACKGROUND AND STUDY AIMS: To assess the cost-effectiveness of introducing endoscopic treatment based on radiofrequency ablation plus endoscopic mucosal resection in selected patients into the standard of care of Barrett's esophagus with high-grade dysplasia or low-grade dysplasia in Spain. METHODS: The disease evolution was modeled via a semi-Markov model. The treatment strategies compared included endoscopic treatment based on radiofrequency ablation plus endoscopic mucosal resection and the Standard of Care (esophagectomy or palliative chemoradiotherapy according to disease status for high-grade dysplasia and endoscopic surveillance for low-grade dysplasia)...
November 23, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29168418/telemedicine-in-diabetic-foot-care-a-systematic-literature-review-of-interventions-and-meta-analysis-of-controlled-trials
#6
Huidi Tchero, Lazarre Noubou, Beatrice Becsangele, Martin Mukisi-Mukaza, Gerald-Reparate Retali, Emmanuel Rusch
The care of individuals with diabetic foot ulcers is costly and requires multiple hospital visits. Inadequate care leads to serious complications and a high risk of lower extremity amputation. In this review, we aimed at evaluating whether telemedicine can be effective in diabetic foot patient care. We searched Medline through Embase and PubMed and Cochrane Central Register of Controlled Trials (CENTRAL) for relevant studies, published up to April 2017. The studies were summarized and discussed in a narrative method and a meta-analysis of 2 controlled trials was conducted using the fixed-effects model...
November 1, 2017: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/29168085/prevalence-of-human-papillomavirus-genotypes-and-abnormal-pap-smears-among-women-in-the-military-health-system
#7
Christopher M Daly, Shana L Hansen, Paul O Kwon, Timothy A Roberts
Human papillomavirus infection (HPV) is the most common sexually transmitted infection among United States Military Servicemembers, and present in the majority of cervical cancers. Many of these infections are preventable, but HPV immunization is not mandatory during military service. The objective of this study was to examine the prevalence of vaccine-preventable cervical disease among women enrolled in the San Antonio Military Health System. This is a retrospective cross-sectional study of Pap smear results and HPV genotyping data among Military Servicewomen and beneficiaries...
November 22, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/29168032/comparison-of-the-mascc-and-cisne-scores-for-identifying-low-risk-neutropenic-fever-patients-analysis-of-data-from-three-emergency-departments-of-cancer-centers-in-three-continents
#8
Shin Ahn, Terry W Rice, Sai-Ching J Yeung, Tim Cooksley
PURPOSE: Patients with febrile neutropenia are a heterogeneous group with a minority developing serious medical complications. Outpatient management of low-risk febrile neutropenia has been shown to be safe and cost-effective. Scoring systems, such as the Multinational Association for Supportive Care in Cancer (MASCC) score and Clinical Index of Stable Febrile Neutropenia (CISNE), have been developed and validated to identify low-risk patients. We aimed to compare the performance of these two scores in identifying low-risk febrile neutropenic patients...
November 22, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29168012/cost-effectiveness-of-rule-based-immunoprophylaxis-against-respiratory-syncytial-virus-infections-in-preterm-infants
#9
Maarten O Blanken, Geert W Frederix, Elisabeth E Nibbelke, Hendrik Koffijberg, Elisabeth A M Sanders, Maroeska M Rovers, Louis Bont
The objective of the paper is to assess the cost-effectiveness of targeted respiratory syncytial virus (RSV) prophylaxis based on a validated prediction rule with 1-year time horizon in moderately preterm infants compared to no prophylaxis. Data on health care consumption were derived from a randomised clinical trial on wheeze reduction following RSV prophylaxis and a large birth cohort study on risk prediction of RSV hospitalisation. We calculated the incremental cost-effectiveness ratio (ICER) of targeted RSV prophylaxis vs...
November 22, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29167902/trends-in-use-of-ambulatory-surgery-centers-for-cataract-surgery-in-the-united-states-2001-2014
#10
Brian C Stagg, Nidhi Talwar, Cynthia Mattox, Paul P Lee, Joshua D Stein
Importance: Cataract surgery is commonly performed at ambulatory surgery centers (ASCs) and hospital outpatient departments (HOPDs). These venues differ in many ways, including surgical efficiency, patient throughput, patient safety, and costs per surgery. Objective: To determine trends in use of ASCs and HOPDs for cataract surgery from 2001 to 2014 and factors affecting the site of surgery. Design, Setting, and Participants: This retrospective longitudinal cohort analysis involved individuals 40 years and older who underwent cataract surgery between January 2001 and December 2014 from a nationwide US managed care network...
November 22, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29167870/association-of-the-hospital-readmissions-reduction-program-with-surgical-readmissions
#11
Tudor Borza, Mary K Oerline, Ted A Skolarus, Edward C Norton, Andrew M Ryan, Chad Ellimoottil, Justin B Dimick, Vahakn B Shahinian, Brent K Hollenbeck
Importance: Readmissions after surgery lead to poor patient outcomes and increased costs. The Hospital Readmissions Reduction Program (HRRP) penalizes hospitals with excess readmissions after specified medical and surgical discharges. Objective: To evaluate the association of the HRRP with readmissions after major joint surgery (targeted) and procedures with historically high rates not under its purview (nontargeted). Design, Setting, and Participants: In this population-based analysis using a 20% Medicare sample, a retrospective cohort study was performed of patients undergoing one of 5 major surgical procedures between January 1, 2006, and November 30, 2014...
November 22, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/29167666/first-year-of-israeli-newborn-screening-for-severe-combined-immunodeficiency-clinical-achievements-and-insights
#12
Erez Rechavi, Atar Lev, Amos J Simon, Tali Stauber, Suha Daas, Talia Saraf-Levy, Arnon Broides, Amit Nahum, Nufar Marcus, Suhair Hanna, Polina Stepensky, Ori Toker, Ilan Dalal, Amos Etzioni, Shlomo Almashanu, Raz Somech
Severe combined immunodeficiency (SCID), the most severe form of T cell immunodeficiency, is detectable through quantification of T cell receptor excision circles (TRECs) in dried blood spots obtained at birth. Herein, we describe the results of the first year of the Israeli SCID newborn screening (NBS) program. This important, life-saving screening test is available at no cost for every newborn in Israel. Eight SCID patients were diagnosed through the NBS program in its first year, revealing an incidence of 1:22,500 births in the Israeli population...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29167092/dry-needling-for-patients-with-neck-pain-protocol-of-a-randomized-clinical-trial
#13
Eric Robert Gattie, Joshua A Cleland, Suzanne J Snodgrass
BACKGROUND: Neck pain is a costly and common problem. Current treatments are not adequately effective for a large proportion of patients who continue to experience recurrent pain. Therefore, new treatment strategies should be investigated in an attempt to reduce the disability and high costs associated with neck pain. Dry needling is a technique in which a fine needle is used to penetrate the skin, subcutaneous tissues, and muscle with the intent to mechanically disrupt tissue without the use of an anesthetic...
November 22, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29166926/protocol-for-a-systematic-review-and-meta-analysis-on-the-clinical-outcomes-and-cost-of-deep-inferior-epigastric-perforator-diep-flap-versus-implants-for-breast-reconstruction
#14
Ankur Khajuria, Oliver J Smith, Maxim Prokopenko, Maximillian Greenfield, Afshin Mosahebi
BACKGROUND: Mastectomy in the context of breast malignancy can have a profoundly negative impact on a woman's self-image, impairing personal, sexual and social relationships. The deep inferior epigastric perforator (DIEP) flap and implants are the two commonest reconstructive modalities that can potentially overcome this psychological trauma. The comparative data on clinical outcomes and costs of the two modalities is limited. We aim to synthesise the current evidence on DIEP versus implants to establish which is the superior technique for breast reconstruction, in terms of clinical outcomes and cost-effectiveness...
November 22, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/29166769/economic-evaluation-of-a-nurse-led-home-and-clinic-based-secondary-prevention-programme-to-prevent-progressive-cardiac-dysfunction-in-high-risk-individuals-the-nurse-led-intervention-for-less-chronic-heart-failure-nil-chf-randomized-controlled-study
#15
Shoko Maru, Joshua Byrnes, Melinda J Carrington, Yih-Kai Chan, Simon Stewart, Paul A Scuffham
OBJECTIVE: The objective of this study was to assess the cost-effectiveness of a long-term, nurse-led, multidisciplinary programme of home/clinic visits in preventing progressive cardiac dysfunction in patients at risk of developing de novo chronic heart failure (CHF). METHODS: A trial-based analysis was conducted alongside a pragmatic, single-centre, open-label, randomized controlled trial of 611 patients (mean age: 66 years) with subclinical cardiovascular diseases (without CHF) discharged to home from an Australian tertiary referral hospital...
November 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29166338/use-of-organs-from-hepatitis-c-virus-positive-donors-for-uninfected-recipients-a-potential-cost-effective-approach-to-save-lives
#16
Patrick B Trotter, Dominic M Summers, Ines Ushiro-Lumb, Matthew Robb, J Andrew Bradley, James Powell, Christopher J E Watson, James Neuberger
BACKGROUND: Organs from hepatitis C virus (HCV) seropositive (HCVpos) individuals are seldom used for transplantation because of the risk of disease transmission. Because transmitted HCV is now amenable to effective treatment we estimated the potential impact of using HCVpos deceased donor organs for transplantation. METHODS: The Potential Donor Audit (PDA) of patients (<80years) dying in UK critical care units and the UK Transplant Registry (UKTR) was searched to identify HCVpos potential and proceeding deceased donors...
November 22, 2017: Transplantation
https://www.readbyqxmd.com/read/29166305/botulinum-toxin-therapy-is-syringe-type-related-to-cost-effectiveness
#17
Mark Anthony Foglietti, Lauren Wright, Alanna Foglietti-Fostyk
INTRODUCTION: Clostridium botulinum toxin is effective through cleaving presynaptic proteins at the neuromuscular junction, which prevents the release of acetylcholine and inhibits muscle contraction. Several serotypes of botulinum toxin (BT) exist; however, only 2 types have been approved by the US Food and Drug Administration for commercial and medical use, A and B. Both types of BT must be administered intramuscularly with a syringe, but the type of syringe is the injector's preference...
November 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29166197/combining-natural-ingredients-and-beliefs-the-dayak-tribe-s-experience-caring-for-sick-children-with-traditional-medicine
#18
Shinta Widiastuty Anggerainy, Dessie Wanda, Happy Hayati
Instead of seeking conventional health care, the Dayak tribe in Borneo, Indonesia, treats sick children at home with traditional medicine. The objective of this descriptive, qualitative study was to explore the Dayak tribe's use of traditional medicine to care for sick children. Comprehensive interviews were conducted with 10 caregivers, with collected data analyzed using content analysis. Key recurring themes identified were: 1) traditional medicine as first aid; 2) ease of access and cost-effectiveness; 3) traditional medicine was not always effective; 4) a combination of natural ingredients and beliefs; 5) the importance of "communicating" with plants; and 6) engagement with metaphysical forces...
2017: Compr Child Adolesc Nurs
https://www.readbyqxmd.com/read/29165380/direct-modification-of-microcrystalline-cellulose-with-ethylenediamine-for-use-as-adsorbent-for-removal-amitriptyline-drug-from-environment
#19
Roosevelt D S Bezerra, Régis C Leal, Mateus S da Silva, Alan I S Morais, Thiago H C Marques, Josy A Osajima, Andréia B Meneguin, Hernane da S Barud, Edson C da Silva Filho
Cellulose derivatives have been widely used as adsorbents for the removal of micropollutants such as drugs, dyes, and metals, due to their abundance, low cost and non-contaminating nature. In this context, several studies have been performed searching for new adsorbents (cellulose derivatives) efficient at contaminant removal from aqueous solutions. Thus, a new adsorbent was synthesized by chemical modification of cellulose with ethylenediamine in the absence of solvent and applied to the adsorption of amitriptyline (AMI) in aqueous solution...
November 22, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29165084/advances-on-automatic-speech-analysis-for-early-detection-of-alzheimer-disease-a-non-linear-multi-task-approach
#20
K Lopez-de-Ipina, U Martinez-de-Lizarduy, P M Calvo, Jiri Mekyska, B Beitia, N Barroso, A Estanga, M Tainta, M Ecay-Torres
Nowadays proper detection of cognitive impairment has become a challenge for the scientific community. Alzheimer's Disease (AD), the most common cause of dementia, has a high prevalence that is increasing at a fast pace towards epidemic level. In the not-so-distant future this fact could have a dramatic social and economic impact. In this scenario, an early and accurate diagnosis of AD could help to decrease its effects on patients, relatives and society. Over the last decades there have been useful advances not only in classic assessment techniques, but also in novel non-invasive screening methodologies...
November 20, 2017: Current Alzheimer Research
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