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drug coated balloon angioplasty

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https://www.readbyqxmd.com/read/29332315/comparison-of-treatment-strategies-for-femoro-popliteal-disease-a-network-meta-analysis
#1
Edward Koifman, Michael J Lipinski, Kyle Buchanan, Won Yu Kang, Ricardo O Escarcega, Ron Waksman, Nelson L Bernardo
OBJECTIVES: We sought to compare treatment strategies in a Bayesian network meta-analysis of randomized controlled trials. BACKGROUND: Peripheral artery disease (PAD) is a prevalent morbidity that is treated with various strategies. METHODS: We performed a MEDLINE search for randomized studies comparing at least 2 treatment strategies, including bypass surgery, percutaneous transluminal angioplasty (PTA) balloons, stents, covered stents, drug-eluting stents (DES), and drug-coated balloons (DCB), in patients with native femoro-popliteal disease...
January 14, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29327573/treating-complex-femoro-popliteal-lesions
#2
Rozemarijn J van der Vijver-Coppen, Yannick W 't Mannetje, Theo P Menting, Jan-Willem Lardenoije, Michel M Reijnen
Peripheral artery disease affects 202 million patients worldwide and may cause disabling intermittent claudication and critical limb ischemia. Next to life style changes, best medical treatment and supervised exercise therapy, it can be necessary to re-vascularise the limb. Treatment of femoro-popliteal lesions poses a challenge and a surgical bypass remains recommended in the guidelines for longer and more complex lesions. Bypass surgery is associated with substantial morbidity and even mortality. Endovascular alternatives are quickly evolving from plain balloon angioplasty to drug-eluting stents, drug-coated balloons, polytetrafluoroethylene covered stents and atherectomy...
January 9, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29326153/treatment-effect-of-drug-coated-balloons-is-durable-to-3-years-in-the-femoropopliteal-arteries-long-term-results-of-the-in-pact-sfa-randomized-trial
#3
Peter A Schneider, John R Laird, Gunnar Tepe, Marianne Brodmann, Thomas Zeller, Dierk Scheinert, Christopher Metzger, Antonio Micari, Ravish Sachar, Michael R Jaff, Hong Wang, Melissa S Hasenbank, Prakash Krishnan
BACKGROUND: Randomized controlled trials have reported favorable 1-year outcomes with drug-coated balloons (DCBs) for the treatment of symptomatic peripheral arterial disease when compared with standard percutaneous transluminal angioplasty (PTA). Evidence remains limited on the durability of the treatment effect with DCBs in the longer term. METHODS AND RESULTS: IN.PACT SFA is a single-blind, randomized trial (Randomized Trial of IN.PACT Admiral Paclitaxel-Coated Percutaneous Transluminal Angioplasty [PTA] Balloon Catheter vs Standard PTA for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery [SFA] and/or Proximal Popliteal Artery [PPA]) that enrolled 331 patients with symptomatic (Rutherford 2-4) femoropopliteal lesions up to 18 cm in length...
January 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29317991/successful-recanalization-of-long-femoro-crural-occlusive-disease-after-failed-bypass-surgery
#4
Grigorios Korosoglou, Tom Eisele, Dorothea Raupp, Christoph Eisenbach, Sorin Giusca
Patients with critical limb ischemia necessitate immediate intervention to restore blood flow to the affected limb. Endovascular procedures are currently preferred for these patients. We describe the case of an 80-year-old female patient who presented to our department with ischemic rest pain and ulceration of the left limb. The patient had history of left femoral popliteal bypass surgery, femoral thromboendarterectomy and patch angioplasty of the same limb 2 years ago. Doppler sonography and magnetic resonance angiography revealed an occlusion of the left superficial femoral artery (SFA) and popliteal artery and of all three infra-popliteal arteries...
December 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/29278215/percutaneous-coronary-intervention-in-the-elderly-are-drug-coated-balloons-the-future
#5
Ioannis Merinopoulos, Tharusha Gunawardena, Upul Wickramarachchi, Alisdair Ryding, Simon Eccleshall, Vassilios S Vassiliou
Balloon angioplasty revolutionised percutaneous treatment for coronary artery disease four decades ago, but vessel-threatening dissections, elastic recoil and restenosis were major drawbacks to an otherwise successful long-lasting intervention. Subsequent advances with bare metal stents and then drug eluting stents followed, aiming to mitigate the risks of acute vessel closure and restenosis. However, stent implantation often necessitates dual antiplatelet therapy for a prolonged period of time, which in itself can lead to adverse outcomes, especially in the frail elderly population at higher risk of bleeding...
December 26, 2017: Current Cardiology Reviews
https://www.readbyqxmd.com/read/29251204/directional-atherectomy-with-antirestenotic-therapy-vs-drug-coated-balloon-angioplasty-alone-for-common-femoral-artery-atherosclerotic-disease
#6
Konstantinos Stavroulakis, Arne Schwindt, Giovanni Torsello, Efthymios Beropoulis, Arne Stachmann, Christiane Hericks, Leonie Bollenberg, Theodosios Bisdas
PURPOSE: To report an experience using directional atherectomy (DA) with antirestenotic therapy (DAART) in the form of drug-coated balloon (DCB) angioplasty vs DCB angioplasty alone in common femoral artery (CFA) occlusive lesions. METHODS: A retrospective review was conducted of 47 consecutive patients (mean age 71 years; 26 men) treated between October 2011 and July 2016 using either DCB angioplasty alone (n=26) or DAART (n=21) for CFA lesions. The majority of patients had lifestyle-limiting claudication (14 DCB and 15 DAART)...
December 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/29248121/percutaneous-drug-eluting-balloon-angioplasty-to-treat-dialysis-access-stenosis
#7
Mafalda Massara, Pietro Finocchiaro, Alberto Volpe, Antonino Alberti, Pietro Volpe
A common complication of arteriovenous fistula for hemodialysis is development of conduit stenosis, which compromises function and can result in access thrombosis. Possible treatment options include open repair and endovascular therapy, with the latter preferred due to lower morbidity and similar outcomes. Recurrence of conduit stenosis is common and, based on the pathophysiology of this lesion, the application of drug-coated balloon angioplasty is attractive. In this report, the application of drug-eluting balloon angioplasty for dialysis access stenosis in 18 consecutive patients is detailed and primary patency rates of 82% at 1 year and 68% at 2 years were calculated...
June 2017: Seminars in Vascular Surgery
https://www.readbyqxmd.com/read/29219030/laser-atherectomy-combined-with-drug-coated-balloon-angioplasty-is-associated-with-improved-1-year-outcomes-for-treatment-of-femoropopliteal-in-stent-restenosis
#8
Damianos G Kokkinidis, Prio Hossain, Omar Jawaid, Bejan Alvandi, T Raymond Foley, Gagan D Singh, Stephen W Waldo, John R Laird, Ehrin J Armstrong
PURPOSE: To examine whether laser atherectomy combined with drug-coated balloons (laser + DCB) can improve the outcomes of femoropopliteal (FP) in-stent restenosis (ISR). METHODS: A dual-center retrospective study was conducted of 112 consecutive patients (mean age 70.3±10.6 years; 86 men) with Tosaka class II (n=29; diffuse stenosis) or III (n=83; occlusion) FP-ISR lesions. Sixty-two patients (mean age 68.5±10 years; 51 men) underwent laser + DCB while the other 50 patients (mean age 72...
December 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/29203209/comparative-efficacy-of-two-paclitaxel-coated-balloons-with-different-excipient-coatings-in-patients-with-coronary-in-stent-restenosis-a-pooled-analysis-of-the-intracoronary-stenting-and-angiographic-results-optimizing-treatment-of-drug-eluting-stent-in-stent
#9
Roisin Colleran, Michael Joner, Sebastian Kufner, Felix Altevogt, Franz-Josef Neumann, Mohamed Abdel-Wahab, Janika Bohner, Christian Valina, Gert Richardt, Bernhard Zrenner, Salvatore Cassese, Tareq Ibrahim, Karl-Ludwig Laugwitz, Heribert Schunkert, Adnan Kastrati, Robert A Byrne
BACKGROUND: Angioplasty with paclitaxel-coated balloons (PCB) is recommended for treatment of patients with coronary in-stent restenosis (ISR) according to European clinical practice guidelines. Most clinical trials have investigated iopromide-based PCB and there is a paucity of data comparing efficacy against butyryl-tri-hexyl citrate (BTHC)-based PCB. Our aim was to compare the performance of two widely-used PCB in the treatment of coronary ISR. METHODS: We analysed patients treated with BTHC- or iopromide-PCB for treatment of drug-eluting stent ISR in the setting of 2 consecutive trials with identical inclusion and exclusion criteria...
November 28, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29161933/safety-of-zilver-ptx-drug-eluting-stent-implantation-following-drug-coated-balloon-dilation-in-a-healthy-swine-model
#10
Sho Torii, Kazuyuki Yahagi, Hiroyoshi Mori, Emanuel Harari, Maria E Romero, Frank D Kolodgie, Brandt Young, Anthony Ragheb, Renu Virmani, Aloke V Finn
PURPOSE: To compare the safety of Zilver PTX drug-eluting stents (DES) following drug-coated balloon (DCB) angioplasty or conventional balloon angioplasty (BA) in a healthy porcine iliofemoral artery model. METHODS: DES implantation following DCB (DCB+DES) or BA (BA+DES) was assessed by angiography and histology in the nondiseased iliofemoral arteries of 20 animals, with sacrifice at 1, 3, and 6 months. Safety assessment compared quantitative measures of vessel integrity (eg, preservation of artery geometry, structure, and lumen dimensions; absence of aneurysm; malapposition) and histological parameters (eg, excessive inflammation)...
November 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/29159684/early-experience-with-a-new-concept-of-angioplasty-nitinol-constrained-balloon-catheter-chocolate-%C3%A2-in-severely-claudicant-patients
#11
Pasqualino Sirignano, Wassim Mansour, Alessandro d'Adamo, Simone Cuozzo, Laura Capoccia, Francesco Speziale
BACKGROUND: To report our experience in treating severely claudicant patients, employing a "nitinol-constrained" balloon (Chocolate, TriReme Medical Inc., Pleasanton, CA-USA) before drug-coated balloon (DCB) in a standardized protocol. METHODS: Eighty-one (84 limbs) consecutive Rutherford category (RC) 3 patients treated between December 2014 and December 2016 for superficial femoral artery (SFA) and popliteal arterial (PA) disease by nitinol-constrained balloon followed by DCB were enrolled...
November 20, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29157024/critical-limb-ischemia-update-and-the-evolving-role-of-drug-elution-technologies
#12
Jared B Hooker, Beau M Hawkins
Critical limb ischemia (CLI) is a prevalent condition associated with cardiovascular mortality and limb loss. Areas covered: This review discusses the epidemiology of CLI, revascularization options, and drug-elution therapies. Expert commentary: Drug-eluting stents (DES) and drug-coated balloons (DCB) improve patency rates in the femoropopliteal segment, and are generally used as first-line therapies. For below-knee disease, angioplasty is the default strategy unless lesions are focal whereby DES can be used to reduce restenosis risk...
December 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/29131504/balloon-pin-hole-rupture-during-percutaneous-coronary-intervention-for-recurrent-calcified-in-stent-restenosis-a-case-report
#13
Nobuhiro Murata, Tadateru Takayama, Takafumi Hiro, Atsushi Hirayama
Percutaneous coronary intervention (PCI) for patients with in-stent restenosis (ISR) is generally considered safe and effective. However, due to increased tissue hardness, PCI for calcified intra-stent ISR is technically challenging. Here, we report severe angioplasty-related complications in a patient presenting with calcified, recurrent ISR following PCI. After receiving drug-coated balloon (DCB) angioplasty for an initial ISR, the patient developed recurrent ISR during the follow-up period. Intravascular imaging revealed intra-stent calcifications and balloon angioplasty was subsequently performed...
November 13, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29125264/drug-coated-balloons-reduce-the-risk-of-recurrent-restenosis-in-arteriovenous-fistulas-and-prosthetic-grafts-for-hemodialysis
#14
Nicola Troisi, Pierfrancesco Frosini, Chiara Somma, Eugenio Romano, Azzurra Guidotti, Pietro C Dattolo, Giuseppe Ferro, Emiliano Chisci, Stefano Michelagnoli
BACKGROUND: Aim of this study was to evaluate the early and mid-term outcomes of drug-coated balloons (DCBs) in hemodialysis patients with recurrent stenosis of arteriovenous fistula and previously treated with plain balloon angioplasty (PBA). METHODS: Between July 2013 and June 2016 38 hemodialysis patients with recurrent stenosis of arteriovenous fistula underwent endovascular treatment with a DCB at our center. All patients were previously treated at the target lesion with a PBA...
November 10, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29078242/-drug-coated-balloon-angioplasty-in-femoropopliteal-arteries-is-there-a-class-effect
#15
Ulf Karl-Martin Teichgräber, Christof Klumb
Aim Percutaneous transluminal angioplasty (PTA) is a well-accepted method to re-establish patency in stenotic and reoccluded vessels. One tool to improve results may be to use paclitaxel drug-coated balloon (DCB) catheters. This systematic review investigates whether there is a class effect among different DCBs. Methods The primary endpoint was "Freedom from Target Lesion Revascularisation" (FfTLR) after 12 months. A systematic literature search was performed in PubMed and risk of bias was assessed of the included trials...
October 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29031986/endovascular-interventions-for-femoropopliteal-peripheral-artery-disease-a-network-meta-analysis-of-current-technologies
#16
REVIEW
Michael R Jaff, Teresa Nelson, Nicole Ferko, Melissa Martinson, Louise H Anderson, Sarah Hollmann
PURPOSE: To use network meta-analysis (NMA) to determine the optimal endovascular strategy for management of femoropopliteal peripheral artery disease (PAD) given the lack of multiple prospective randomized trials to guide treatment decisions. MATERIALS AND METHODS: NMA is a new meta-analytic method that permits comparisons among any 2 therapies by combining results of a collection of clinical trials conducted in the same or similar patient population. NMA was used to analyze data from 15 randomized controlled trials (RCTs) and 10 prospective, multicenter, single-arm trials (combined evidence [CE] NMA) that evaluated target lesion revascularization (TLR) for 5 endovascular strategies: bare metal stent (BMS), polymer-covered metal stent (CMS), drug-eluting stent (DES), drug-coated balloon (DCB) and percutaneous transluminal angioplasty (PTA)...
December 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29027735/temporal-trends-in-percutaneous-coronary-interventions-thru-the-drug-eluting-stent-era-insights-from-18-641-procedures-performed-over-12-year-period
#17
Uri Landes, Tamir Bental, Amos Levi, Abid Assali, Hana Vaknin-Assa, Eli I Lev, Eldad Rechavia, Gabriel Greenberg, Katia Orvin, Ran Kornowski
BACKGROUND: The last decade, regarded as the DES era in PCI, has witnessed significant advances in the management of coronary disease. We aimed to assess temporal trends in the practice and outcome of percutaneous coronary intervention (PCI) during the drug eluting stent (DES) era. METHODS: We analyzed 18,641 consecutive PCI's performed between January 2004 and December 2016, distinguished by procedural date (Q1 : 2004-2006, n = 4,865; Q2 : 2007-2009, n = 4,977; Q3 : 2010-2012, n = 4,230; Q4 : 2013-2016, n = 4,569)...
October 13, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28980462/treatment-of-femoropopliteal-atherosclerotic-lesions-using-the-ranger-paclitaxel-coated-balloon-catheter-12-month-results-from-an-all-comers-registry
#18
Michael Lichtenberg, Peter von Bilderling, Jürgen Ranft, Kathrin Niemöller, Holger Grell, Lucas Briner, Françoise Saucy, Tienush Rassaf, Frank Breuckmann
BACKGROUND: To evaluate 12-month effectiveness of the endovascular treatment of femoropopliteal (FP) atherosclerotic lesions with the Ranger drug-coated balloon (DCB) in a real-world setting. METHODS: In this prospective, observational, multicenter trial (ClinicalTrials.gov Identifier: NCT02462005) 172 consecutive patients with 226 de novo, restenosed, or reoccluded native superficial femoral and/or popliteal artery lesions were treated with the Ranger paclitaxel- coated balloon angioplasty...
October 3, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28975778/debulking-plus-drug-coated-balloon-combination-as-revascularization-strategy-for-complex-femoropopliteal-lesions
#19
Katia Dessi, Luca Giovannacci, Jos C Vand den Berg
This paper will discuss the results from the most recent randomized trials and large registries for DCB's and atherectomy, and the drawbacks of these 2 therapeutic options. It will also discuss the results of combination therapy in complex femoropopliteal lesions. Several studies indicate that combining atherectomy and DCB yields better outcomes in complex calcified lesions, but the only randomized pilot study could not demonstrate a benefit of combination therapy in the mid-term follow-up. Larger, randomized studies are needed to define the role of atherectomy followed by DCB angioplasty further...
October 2, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28975777/the-evolving-role-of-drug-coated-balloons-for-the-treatment-of-complex-femoropopliteal-lesions
#20
Grigorios Korosoglou, Michael Lichtenberg, Sultan Celik, Joachim Andrassy, Marianne Brodmann, Martin Andrassy
INTRODUCTION: Conventional therapies for transcatheter treatment of patients with infrainguinal obstructive disease remain compromised by high restenosis rates. Drug-coated balloons (DCB) offer a novel therapeutic alternative targeting the source of neo-intimal hyperplasia, without the need for a permanent endovascular scaffold and their inherent limitations. EVIDENCE ACQUISITION: A systematic research of the medical databases (Pubmed) has been conducted for this up-to-date review...
October 2, 2017: Journal of Cardiovascular Surgery
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