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Neonatal MRI

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https://www.readbyqxmd.com/read/28631523/the-association-among-prematurity-cochlear-hyperintensity-and-hearing-loss
#1
Michael A Wien, Matthew T Whitehead
Background Prematurity is a major risk factor for neonatal hearing loss. Recent advancements in magnetic resonance imaging (MRI) have made it possible to evaluate structural details of the membranous labyrinths in premature infants that have heretofore been inaccessible. Objective We compared the prevalence of abnormal cochlear signal intensity in premature and term neonates and evaluated for a potential link with hearing loss. Materials and methods We retrospectively reviewed 148 consecutive MR exams performed in premature (< 37 weeks' gestation) and term neonates performed over a 30-month period...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28629418/prenatal-brain-disruption-in-isolated-sulfite-oxidase-deficiency
#2
Hsiu-Fen Lee, Ching-Shiang Chi, Chi-Ren Tsai, Hung-Chieh Chen, I-Chun Lee
BACKGROUND: Isolated sulfite oxidase deficiency (ISOD) is a very rare autosomal recessive inherited neurometabolic disease. The most striking postnatal neuroimaging finding is multicystic encephalomalacia, which occurs rapidly within days to weeks after birth and mimics severe hypoxic-ischemic encephalopathy. The aim of this study was to describe the prenatal neuroimaging features in a neonate and a fetus diagnosed with ISOD. RESULTS: We report an 11-day-old female neonate who presented with feeding difficulties, decreased activity, neonatal seizures, and movement disorders within a few days after birth...
June 19, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28626962/three-dimensional-motion-corrected-sensitivity-encoding-reconstruction-for-multi-shot-multi-slice-mri-application-to-neonatal-brain-imaging
#3
Lucilio Cordero-Grande, Emer J Hughes, Jana Hutter, Anthony N Price, Joseph V Hajnal
PURPOSE: To introduce a methodology for the reconstruction of multi-shot, multi-slice magnetic resonance imaging able to cope with both within-plane and through-plane rigid motion and to describe its application in structural brain imaging. THEORY AND METHODS: The method alternates between motion estimation and reconstruction using a common objective function for both. Estimates of three-dimensional motion states for each shot and slice are gradually refined by improving on the fit of current reconstructions to the partial k-space information from multiple coils...
June 19, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28623417/a-validated-clinical-mri-injury-scoring-system-in-neonatal-hypoxic-ischemic-encephalopathy
#4
Shamik B Trivedi, Zachary A Vesoulis, Rakesh Rao, Steve M Liao, Joshua S Shimony, Robert C McKinstry, Amit M Mathur
BACKGROUND: Deep nuclear gray matter injury in neonatal hypoxic-ischemic encephalopathy (HIE) is associated with worse neurodevelopmental outcomes. We previously published a qualitative MRI injury scoring system utilizing serial T1-weighted, T2-weighted and diffusion-weighted imaging (DWI), weighted for deep nuclear gray matter injury. OBJECTIVES: To establish the validity of the MRI scoring system with neurodevelopmental outcome at 18-24 months. MATERIALS AND METHODS: MRI scans from neonates with moderate to severe HIE treated with therapeutic hypothermia were evaluated...
June 16, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28623069/neonatal-hypoglycemia-a-wide-range-of-electroclinical-manifestations-and-seizure-outcomes
#5
Ebru Arhan, Zeynep Öztürk, Ayşe Serdaroğlu, Kürşad Aydın, Tuğba Hirfanoğlu, Yılmaz Akbaş
PURPOSE: We examined the various types of epilepsy in children with neonatal hypoglycemia in order to define electroclinical and prognostic features of these patients. METHOD: We retrospectively reviewed the medical records of patients with a history of symptomatic neonatal hypoglycaemia who have been followed at Gazi University Hospital Pediatric Neurology Department between 2006 and 2015. Patients with perinatal asphyxia were excluded. Details of each patient's perinatal history, neurological outcome, epilepsy details, seizure outcome and EEG and brain MRI findings were reviewed...
June 1, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/28614860/primary-fetal-lung-hypoplasia-pflh-imaging-and-clinical-characteristics
#6
Reuven Achiron, Yinon Gilboa, Yishay Salem, Yizhak Jacobson, Lisa Raviv-Zilka, Andreea Cioca, Debora Kidron, Zvi Kivilevitch
Purpose To describe in utero and postnatal imaging and clinical characteristics of primary fetal lung hypoplasia (PFLH). Methods A retrospective review of fetuses and neonates diagnosed in one academic tertiary center during an eleven-year period. Results 12 cases of PFLH were identified. 4 were bilateral and 8 had unilateral involvement. Prenatal sonographic characteristics, postnatal magnetic resonance imaging (MRI), computerized tomographic angiography (CTA), and histologic findings are described...
June 2017: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/28612638/should-isolated-fetal-ventriculomegaly-measured-below-12%C3%A2-mm-be-viewed-as-a-variant-of-the-norm-results-of-a-5-year-experience-in-a-prenatal-referral-center
#7
Anaïs Lavongtheung, Guillaume Jedraszak, Philippe Naepels, Pierre Tourneux, Catherine Gondry-Jouet, Anne-Gaëlle L E Moing, Jean Gondry, Julien Chevreau
BACKGROUND: Fetal ventriculomegaly (VM) is defined as lateral ventricles measured above 10 mm. Some authors believe VM < 12 mm are variants of the norm and needn't be addressed for referral ultrasound. METHODS: A retrospective continuous cohort study of 127 confirmed fetal VM was divided in 3 groups after initial referral sonographic assessment: isolated VM < 12 mm (group A), isolated VM ≥ 12 mm (group B), and VM associated with other malformations (group C)...
June 14, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28603687/prematurity-and-brain-perfusion-arterial-spin-labeling-mri
#8
Domenico Tortora, Peter Angelo Mattei, Riccardo Navarra, Valentina Panara, Rita Salomone, Andrea Rossi, John A Detre, Massimo Caulo
PURPOSE: Abnormal brain perfusion is a critical mechanism in neonatal brain injury. The aim of the present study was to compare Cerebral Blood Flow (CBF) evaluated with ASL MRI in three groups of neonates: preterms without brain lesions on MRI (PN), preterms with periventricular white matter lesions (PNp) and term neonates with normal MRI (TN). The correlation between CBF and clinical outcome was explored. MATERIALS AND METHODS: The institutional review board approved this prospective study and waived informed consent...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28601980/plicae-palmatae-in-neonates-tumor-mimic-on-sonography
#9
Masahiro Kitami
Plicae palmatae are uterine cervical folds that can be misdiagnosed as a uterine septum on magnetic resonance imaging (MRI). Previous studies in the literature generally tend to include only adults and are limited to MRI findings. Here, we present the case of a 6-day-old girl with a tumorous lesion in her uterine isthmus on sonography. Although we considered uterine tumor as a differential diagnosis, the smooth surface and continuity with a cervical fold on the caudal side suggested that the lesion was, in fact, the tip of plicae palmatae...
June 10, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28594884/correlation-between-white-matter-microstructure-and-executive-functions-suggests-early-developmental-influence-on-long-fibre-tracts-in-preterm-born-adolescents
#10
Brigitte Vollmer, Aiko Lundequist, Gustaf Mårtensson, Zoltan Nagy, Hugo Lagercrantz, Ann-Charlotte Smedler, Hans Forssberg
MAIN OBJECTIVES: Executive functions are frequently a weakness in children born preterm. We examined associations of executive functions and general cognitive abilities with brain structure in preterm born adolescents who were born with appropriate weight for gestational age and who have no radiological signs of preterm brain injury on neuroimaging. METHODS: The Stockholm Neonatal Project (SNP) is a longitudinal, population-based study of children born preterm (<36 weeks of gestation) with very low birth weight (<1501g) between 1988-1993...
2017: PloS One
https://www.readbyqxmd.com/read/28589258/a-latent-measure-explains-substantial-variance-in-white-matter-microstructure-across-the-newborn-human-brain
#11
Emma J Telford, Simon R Cox, Sue Fletcher-Watson, Devasuda Anblagan, Sarah Sparrow, Rozalia Pataky, Alan Quigley, Scott I Semple, Mark E Bastin, James P Boardman
A latent measure of white matter microstructure (g WM) provides a neural basis for information processing speed and intelligence in adults, but the temporal emergence of g WM during human development is unknown. We provide evidence that substantial variance in white matter microstructure is shared across a range of major tracts in the newborn brain. Based on diffusion MRI scans from 145 neonates [gestational age (GA) at birth range 23(+2)-41(+5) weeks], the microstructural properties of eight major white matter tracts were calculated using probabilistic neighborhood tractography...
June 6, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28588126/differences-in-subependymal-vein-anatomy-may-predispose-preterm-infants-to-gmh-ivh
#12
Domenico Tortora, Mariasavina Severino, Mariya Malova, Alessandro Parodi, Giovanni Morana, Jan Sedlacik, Paul Govaert, Joseph J Volpe, Andrea Rossi, Luca Antonio Ramenghi
BACKGROUND AND PURPOSE: The anatomy of the deep venous system plays an important role in the pathogenesis of brain lesions in the preterm brain as shown by different histological studies. The aims of this study were to compare the subependymal vein anatomy of preterm neonates with germinal matrix haemorrhage-intraventricular haemorrhage (GMH-IVH), as evaluated by susceptibility-weighted imaging (SWI) venography, with a group of age-matched controls with normal brain MRI, and to explore the relationship between the anatomical features of subependymal veins and clinical risk factors for GMH-IVH...
June 6, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28586151/a-heterozygous-microdeletion-of-20p12-2-3-encompassing-prokr2-and-bmp2-in-a-patient-with-congenital-hypopituitarism-and-growth-hormone-deficiency
#13
Samuel J H Parsons, Neville B Wright, Emma Burkitt-Wright, Mars S Skae, Phillip G Murray
Congenital growth hormone deficiency is a rare disorder with an incidence of approximately 1 in 4,000 live births. Pituitary development is under the control of a multitude of spatiotemporally regulated signaling molecules and transcription factors. Mutations in the genes encoding these molecules can result in hypopituitarism but for the majority of children with congenital hypopituitarism, the aetiology of their disease remains unknown. The proband is a 5-year-old girl who presented with neonatal hypoglycaemia and prolonged jaundice...
June 6, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28583705/associations-of-newborn-brain-magnetic-resonance-imaging-with-long-term-neurodevelopmental-impairments-in-very-preterm-children
#14
Peter J Anderson, Karli Treyvaud, Jeffrey J Neil, Jeanie L Y Cheong, Rodney W Hunt, Deanne K Thompson, Katherine J Lee, Lex W Doyle, Terrie E Inder
OBJECTIVE: To determine the relationship between brain abnormalities on newborn magnetic resonance imaging (MRI) and neurodevelopmental impairment at 7 years of age in very preterm children. STUDY DESIGN: A total of 223 very preterm infants (<30 weeks of gestation or <1250 g) born at Melbourne's Royal Women's Hospital had a brain MRI scan at term equivalent age. Scans were scored using a standardized system that assessed structural abnormality of cerebral white matter, cortical gray matter, deep gray matter, and cerebellum...
June 2, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28580040/pseudo-prune-belly-syndrome-diagnosis-revealed-by-imaging-a-case-report-and-brief-review
#15
Hemal Grover, Sanjay Sethi, Jatin Garg, Amrit Pal Ahluwalia
BACKGROUND: Prune Belly Syndrome (PBS) is a rare entity, usually found in male neonates. It comprises complex urinary tract anomalies, bilateral undescended testis and absence of anterior abdominal wall muscles. Patients with unilateral abdominal wall deficiency, unilateral undescended testis and female neonates with abdominal wall laxity are classified as Pseudo Prune Belly syndrome (PPBS). Reports on PPBS do not highlight the radiological and imaging characteristics of this syndrome and the current literature on the role of newer imaging modalities, such as Magnetic Resonance Imaging (MRI), remains relatively sparse...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28576520/clinical-characterization-of-novel-chromosome-22q13-microdeletions
#16
Jennifer F Ha, Ayesha Ahmad, Marci M Lesperance
INTRODUCTION: The advent of chromosome microarray analysis (CMA) for evaluation of patients with multiple congenital anomalies has made it possible to define chromosomal imbalances with greater precision and resolutions significantly smaller than possible by standard G-banded chromosome analysis. We describe two patients with novel chromosomal anomalies involving chromosome 22q13, a locus also associated with Phelan-McDermid syndrome (PMS). OBJECTIVE: We aim to characterize the novel phenotypic and genotypic findings of two patients with 22q13 microdeletions, distinct from PMS, comparing and contrasting with features of PMS...
April 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28573895/impacts-of-therapeutic-hypothermia-on-cardiovascular-hemodynamics-in-newborns-with-hypoxic-ischemic-encephalopathy-a-case-control-study-using-echocardiography
#17
Ji Hong Yoon, Eun-Jung Lee, Sook Kyung Yum, Cheong-Jun Moon, Youn Young-Ah, Yoo Jin Kwun, Jae Young Lee, In Kyung Sung
PURPOSE: The effects of therapeutic hypothermia (TH) on hemodynamics in newborns with hypoxic-ischemic encephalopathy (HIE) were evaluated. MATERIALS AND METHODS: Thirty-two neonates (gestational age, 39.4 ± 1.3 weeks) who had TH for HIE and echocardiographic hemodynamic assessments during TH and post-TH period were studied. Gestational-age-matched 34 healthy neonates were enrolled for comparison. RESULTS: During TH, patients had significantly decreased left ventricular cardiac output (LVCO), descending aorta blood flow (DABF), and DABF/LVCO ratio, and increased resistive index of DA compared to controls...
June 2, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28559076/prenatal-diagnosis-and-multimodal-neonatal-treatment-of-a-rare-pial-arteriovenous-fistula-case-report-and-review-of-the-literature
#18
Alessandro Pedicelli, Marta Iacobucci, Paolo Frassanito, Emilio Lozupone, Concezio Di Rocco, Cesare Colosimo
Intracranial pial arteriovenous fistulas (PAVFs) are direct communications between the arterial and venous system of the brain, with the characteristic absence of a plexiform nidus, as seen in the classic cerebral arteriovenous malformations. These vascular malformations, usually occurring in the pediatric population, are very rarely diagnosed in uterus, due to a lack of understanding of the condition and because they may be hard to visualize. We report a rare case of a mass effect PAVF diagnosed with fetal MRI, involving the right cerebral hemisphere, fed by a pericallosal artery and associated with a giant venous dilatation...
May 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28555348/-magnetic-resonance-imaging-recent-studies-on-biological-effects-of-static-magnetic-and-high%C3%A2-frequency-electromagnetic-fields
#19
REVIEW
B Pophof, G Brix
PROBLEM: During the last few years, new studies on biological effects of strong static magnetic fields and on thermal effects of high-frequency electromagnetic fields used in magnetic resonance imaging (MRI) were published. Many of these studies have not yet been included in the current safety recommendations. METHOD: Scientific publications since 2010 on biological effects of static and electromagnetic fields in MRI were researched and evaluated. RESULTS: New studies confirm older publications that have already described effects of static magnetic fields on sensory organs and the central nervous system, accompanied by sensory perceptions...
May 29, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28551036/a-patient-with-muenke-syndrome-manifesting-migrating-neonatal-seizures
#20
Yukimune Okubo, Taro Kitamura, Mai Anzai, Wakaba Endo, Takehiko Inui, Yusuke Takezawa, Sato Suzuki-Muromoto, Takuya Miyabayashi, Noriko Togashi, Hiroshi Oba, Hirotomo Saitsu, Naomichi Matsumoto, Kazuhiro Haginoya
We report a patient with Muenke syndrome who had repetitive apneic spell followed by focal status epilepticus in the early infancy. Ictal EEG showed focal spikes bursts originated from the left hemisphere and sifted to the right hemisphere, during which he had migrating tonic seizures from right side of the body to the left side of the body. Brain MRI showed abnormal development of bilateral hippocampus, which was characterized as abnormal folding of hippocampal gyri. However, the long-term seizure prognosis was favorable...
May 24, 2017: Brain & Development
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