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https://www.readbyqxmd.com/read/28196662/a-less-intensive-bracing-protocol-for-pectus-carinatum
#1
George Wahba, Ahmed Nasr, Marcos Bettolli
OBJECTIVES: Despite the widespread use of bracing to correct Pectus carinatum (PC) there is no consensus in the number of hours per day patients are instructed to wear the brace. In our practice, we use a less rigorous protocol of 8-12h/day. We sought to evaluate our results and those in the literature to determine whether more intensive usage is necessary. STUDY DESIGN: We reviewed the outcomes of patients with PC treated at our institution between 2012 and 2015...
January 31, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28044041/visual-diagnosis-a-child-with-presumed-reactive-airway-disease-pectus-carinatum-and-aortic-root-dilation
#2
REVIEW
Aamir Jeewa, Shaine A Morris, William J Dreyer, Iki Adachi, Susan W Denfield, E Dean McKenzie
No abstract text is available yet for this article.
January 2017: Pediatrics in Review
https://www.readbyqxmd.com/read/28001248/effect-of-lectin-scll-on-fibroblasts-stimulated-with-lps-an-in-vitro-study
#3
Manuella Verdinelli de Paula Reis, Camilla Christian Gomes Moura, Marcus Vinicius da Silva, Maria Aparecida de Souza, Priscilla Barbosa Ferreira Soares, Carlos José Soares
The lectin (ScLL) extracted from the Synadenium carinatum plant has been evaluated as an immunomodulator in diseases such as asthma, neosporosis and leishmaniasis. However, it has not yet been evaluated in the oral cavity. This study evaluated the effect of ScLL on viability, proliferation and release of IL-10 in human gingival fibroblasts (HGF) stimulated with lipopolysaccharide (LPS). HGF were stimulated with LPS 1 µg/ml and treated with ScLL in concentrations of 10, 5 and 2 µg/ml for 1 and 5 h, and evaluated by flow cytometry for viability, apoptosis (initial/advanced) and necrosis...
December 22, 2016: Brazilian Oral Research
https://www.readbyqxmd.com/read/27979613/mucopolysaccharidosis-iva-and-glycosaminoglycans
#4
REVIEW
Shaukat Khan, Carlos J Alméciga-Díaz, Kazuki Sawamoto, William G Mackenzie, Mary C Theroux, Christian Pizarro, Robert W Mason, Tadao Orii, Shunji Tomatsu
Mucopolysaccharidosis IVA (MPS IVA; Morquio A: OMIM 253000) is a lysosomal storage disease with an autosomal recessive trait caused by the deficiency of N-acetylgalactosamine-6-sulfate sulfatase. Deficiency of this enzyme leads to accumulation of specific glycosaminoglycans (GAGs): chondroitin-6-sulfate (C6S) and keratan sulfate (KS). C6S and KS are mainly produced in the cartilage. Therefore, the undegraded substrates are stored primarily in cartilage and in its extracellular matrix (ECM), leading to a direct impact on cartilage and bone development, and successive systemic skeletal dysplasia...
January 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/27942072/pectus-carinatum-repair-in-an-adolescent-with-hyperhomocysteinaemia-anaesthetic-implications
#5
Prachi Kar, Suresh Kumar Chintha, Padmaja Durga, Ramachandran Gopinath
No abstract text is available yet for this article.
November 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/27933277/lectins-from-synadenium-carinatum-scll-and-artocarpus-heterophyllus-artinm-are-able-to-induce-beneficial-immunomodulatory-effects-in-a-murine-model-for-treatment-of-toxoplasma-gondii-infection
#6
Eliézer L P Ramos, Silas S Santana, Murilo V Silva, Fernanda M Santiago, Tiago W P Mineo, José R Mineo
Infection by Toxoplasma gondii affects around one-third of world population and the treatment for patients presenting toxoplasmosis clinically manifested disease is mainly based by a combination of sulfadiazine, pyrimethamine, and folinic acid. However, this therapeutic protocol is significantly toxic, causing relevant dose-related bone marrow damage. Thus, it is necessary to improve new approaches to investigate the usefulness of more effective and non-toxic agents for treatment of patients with toxoplasmosis...
2016: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/27836367/success-and-duration-of-dynamic-bracing-for-pectus-carinatum-a-four-year-prospective-study
#7
Sherif Emil, Marika Sévigny, Kathleen Montpetit, Robert Baird, Jean-Martin Laberge, Jade Goyette, Ian Finlay, Guylaine Courchesne
BACKGROUND: This study sought to establish factors that can prognosticate outcomes of bracing for pectus carinatum (PC). METHODS: Prospective data were collected on all patients enrolled in a dynamic bracing protocol from July 2011 to July 2015. Pressure of correction (POC) was measured at initiation of treatment, and pressure of treatment (POT) was measured pre- and post-adjustment at every follow-up visit. Univariate and Cox regression analysis tested the following possible determinants of success and bracing duration: age, sex, symmetry, POC, and POT drop during the first two follow-up visits...
January 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27825548/is-the-abramson-technique-effective-in-pectus-carinatum-repair
#8
Ozgur Katrancioglu, Yucel Akkas, Sule Karadayi, Ekber Sahin, Melih Kaptanoğlu
BACKGROUND: The minimally invasive pectus carinatum (PC) surgery described by Abramson has been performed in many centers. We have been using this technique since 2011. This article describes our experience with PC correction. METHODS: Between 2011 and 2016, 32 patients at our institution underwent minimally invasive repair of a PC deformity. All patients presented with cosmetic complaints. The deformity involved the lower sternum (all had chondrogladiolar type PC), and three patients had asymmetrical deformities...
November 4, 2016: Asian Journal of Surgery
https://www.readbyqxmd.com/read/27761411/30-months-follow-up-of-an-early-enzyme-replacement-therapy-in-a-severe-morquio-a-patient-about-one-case
#9
J Do Cao, A Wiedemann, T Quinaux, S F Battaglia-Hsu, L Mainard, R Froissart, C Bonnemains, S Ragot, B Leheup, P Journeau, F Feillet
: Patients under 5 years were not evaluated in the phase-3 study for enzyme replacement therapy (ERT) in MPS IV A. Here we describe the evolution of a severe Morquio A pediatric patient who was diagnosed at 19 months old and treated by ERT at 21 months old for the next 30 months. Applying the standard ERT protocol on this very young patient appeared to reduce his urinary excretion of glycosaminoglycans (GAGs); the improvements in both the 6 minute-walk test (6MWT) and the stair climb test, however, were no different than those reported in the nature history study...
December 2016: Molecular Genetics and Metabolism Reports
https://www.readbyqxmd.com/read/27747176/the-sandwich-technique-for-repair-of-pectus-carinatum-and-excavatum-carinatum-complex
#10
Hyung Joo Park, Kyung Soo Kim
BACKGROUND: Simple external compression of pectus carinatum seems to have its limitations, particularly the repair of asymmetric pectus carinatum or excavatum/carinatum complex. We devised the sandwich technique (press-molding) to remodel the entire chest wall. The purpose of this study is to introduce the sandwich technique and appraise the early results. METHODS: Between January 2007 and January 2016, 523 consecutive patients with pectus carinatum and its variants were analyzed retrospectively...
September 2016: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/27709644/a-case-of-hypopituitarism-accompanying-kearns-sayre-syndrome-treated-with-human-chorionic-gonadotropin-a-case-report-and-literature-review
#11
Y-X Kang, Y-J Wang, Q Zhang, X-H Pang, W Gu
Kearns-Sayre syndrome (KSS) is a disorder caused by mutations in mitochondrial DNA. Here, we report an unusual case of Kearns-Sayre syndrome accompanied by hypopituitarism (deficiencies in reproductive and growth hormones). A 20-year-old male presented with growth retardation for the last 8 years, as well as the following findings: short stature, delayed puberty, myasthenia, an extraocular movement deficit, drooping eyelids, pectus carinatum and scoliosis. Cerebral enhanced magnetic resonance imaging revealed dysplasias of the pituitary, white matter and cerebellum...
October 6, 2016: Andrologia
https://www.readbyqxmd.com/read/27619474/characterization-of-phloroglucinol-enriched-fractions-of-brazilian-hypericum-species-and-evaluation-of-their-effect-on-human-keratinocytes-proliferation
#12
Henrique Bridi, Aline Beckenkamp, Gari Vidal Ccana-Ccapatinta, Sérgio Augusto de Loreto Bordignon, Andréia Buffon, Gilsane Lino von Poser
In this study, a phytochemical and biological investigation on five South Brazilian Hypericum species (Hypericum caprifoliatum, Hypericum carinatum, Hypericum connatum, Hypericum myrianthum, and Hypericum polyanthemum) was carried out. The phloroglucinol-enriched fractions (PEF) of the flowering aerial parts were analyzed by high-performance liquid chromatography for the content of uliginosin A (1), japonicin A (2), uliginosin B (3), hyperbrasilol B (4), and the three benzopyrans, that is, 6-isobutyryl-5,7-dimethoxy-2,2-dimethyl-benzopyran (HP1) (5), 7-hydroxy-6-isobutyryl-5-methoxy-2,2-dimethyl-benzopyran (HP2) (6), and 5-hydroxy-6-isobutyryl-7-methoxy-2,2-dimethyl-benzopyran (HP3) (7)...
January 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/27543649/endoscopic-atrioventricular-valve-surgery-in-adults-with-difficult-to-access-uncorrected-congenital-chest-wall-deformities
#13
Johan van der Merwe, Filip Casselman, Bernard Stockman, Yvette Vermeulen, Ivan Degrieck, Frank Van Praet
OBJECTIVES: This study presents the first report on in-hospital and long-term outcomes of endoscopic port access atrioventricular valve surgery (EPAAVVS) in adult patients with uncorrected congenital chest wall deformities (CCWDs). METHODS: Our current surgical team performed EPAAVVS in 7 consecutive adult patients (mean age 51.3 ± 16.4 years, 14.3% female, 50% older than 60 years, mean EuroSCORE II 0.8 ± 0.1%) with uncorrected CCWDs between 1 November 2009 and 30 November 2015...
December 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27521175/a-20-year-review-of-pectus-surgery-an-analysis-of-factors-predictive-of-recurrence-and-outcomes
#14
Theofano Tikka, Maninder S Kalkat, Ehab Bishay, Richard S Steyn, Pala B Rajesh, Babu Naidu
OBJECTIVES: Only a few studies report the long-term outcomes following repair of pectus excavatum (PE) and pectus carinatum (PC). Predictors of recurrence after surgery are important in this group of young patients. The purpose of this study was to assess the short- and long-term outcomes of both PE and PC and identify factors associated with postoperative complications and pectus recurrence. METHODS: This was a retrospective observational study that included all patients who underwent primary or recurrent repair of PC and PE in a regional thoracic centre over 20 years...
December 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27465193/complications-related-to-pectus-carinatum-correction-lessons-learned-from-15-years-experience-management-and-literature-review
#15
Barbara Del Frari, Stephan Sigl, Anton H Schwabegger
BACKGROUND: Various methods of corrective thoracoplasty for pectus carinatum deformity have been described, but to date no studies describe a review of complications and how to manage them. Complications are dependent not only on the technique used and the patient's age, but also on the experience of the treating surgeon. The authors present their 15 years' experience with surgical correction of pectus carinatum and the complications that have occurred. A literature review regarding complications with pectus carinatum surgery is performed...
August 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27423936/-the-unsightly-chest-analysis-and-anomaly-curative-or-palliative-approach
#16
P Faglin, É Nectoux, A Belkhou, P Guerreschi, V Duquennoy-Martinot
Anterior chest wall deformity are mostly represented by pectus excavatum, which is a depression of the chondrosternal plastron from the 3rd to the 7th pairs of the costal cartilages, then by pectus carinatum which conversely represents a protrusion of this plastron. The major esthetic and psychosocial impact is not to be demonstrated anymore whereas the cardiopulmonary functional impact remains still highly debated. Regarding the management, curative surgical techniques such as Wurtz's sub-perichondrial simplified sternochondroplasty or Nuss' minimaly invasive technique are opposed to palliative filling technique such as customized silicone implant, lipostructure and flaps...
October 2016: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/27395868/redescription-of-the-genus-cheleocloeon-wuillot-gillies-1993-ephemeroptera-baetidae-with-descriptions-of-three-new-species-from-zambia-and-uganda
#17
Nikita J Kluge
Revised characteristics of Cheleocloeon Wuillot & Gillies 1993 are given. This taxon occupies a separate position within Anteropatellata. The species described as Cheleocloeon mirandei Lugo-Ortiz & McCafferty 1997 and Cheleocloeon sigiense Gillies 2001, as well as the species originally described as Centroptilum falcatum Crass 1947, do not belong to Cheleocloeon. Three new species, Ch. clavifolium sp. n., Ch. lancetofolium sp. n. and C. truncifolium sp. n. from Zambia and Uganda are described based on larvae, subimagoes, imagoes of both sexes and eggs associated by rearing...
January 21, 2016: Zootaxa
https://www.readbyqxmd.com/read/27395626/revision-of-the-anthidiellum-cockerell-1904-of-china-hymenoptera-apoidea-megachilidae-anthidiini
#18
Ze-Qing Niu, John S Ascher, A-Rong Luo, Terry Griswold, Chao-Dong Zhu
The resin bees of the genus Anthidiellum Cockerell, 1904 are revised for China. Seven species are confirmed to occur in China including five new combinations: A. (Pycnanthidium) carinatum (Wu, 1962) comb. nov., A. (P.) coronum (Wu, 2004a) comb. nov., A. (P.) latipes (Bingham, 1897) comb. nov., A. (Clypanthidium) popovii (Wu, 1962) comb. nov., and A. (Anthidiellum) yunnanensis (Wu, 1962) comb. nov.. These five species had previously been classified as Trachusa (Paraanthidium), which is characterized by much larger-bodied bees (only four species of Trachusa (Paraanthidium) are confirmed to occur in China after this study; others reported in the literature were misplaced to genus)...
June 23, 2016: Zootaxa
https://www.readbyqxmd.com/read/27394828/studies-of-peruvian-ptiliidae-coleoptera-4-peruvium-a-new-subgenus-of%C3%A2-ptenidium-with-seven-new-species
#19
Michael Darby
Peruvium a new subgenus of Ptenidium Erichson with seven new species: P. brevissimum sp. n.; P. carinatum sp. n.; P. capillatum sp. n.; P. contractum sp. n.; P. gibbosum sp. n.; P. inornatum sp. n. and P. grande sp. n. is described and figured. The insects were collected by Dr Caroline Chaboo and her students at the University of Kansas as part of a programme to compile an inventory of leaf beetles in Peru and are the first records of Ptenidium from the country. A key is provided.
May 3, 2016: Zootaxa
https://www.readbyqxmd.com/read/27366555/anaesthetic-management-of-laparoscopic-morgagni-hernia-repair-in-a-patient-with-coexisting-down-syndrome-patent-foramen-ovale-and-pectus-carinatum
#20
Betül Kozanhan, Betül Başaran, Feride Aygın, İbrahim Akkoyun, Sadık Özmen
Laparoscopic repair has several advantages with a minimally invasive surgical option for children with Morgagni hernias; however, a number of physiological sequelae results from pneumoperitoneum and insufflation. These physiological changes may be more significant in patients with a congenital heart disease. Perioperative detailed evaluation, meticulous monitorization and cooperation with a surgical team are important in cases with patent foramen ovale for the possible risk of the paradoxical gas embolism. We present the anaesthetic management of a patient with patent foramen ovale, Down syndrome and pectus carinatus who successfully underwent laparoscopic Morgagni hernia repair...
February 2016: Turkish Journal of Anaesthesiology and Reanimation
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