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https://www.readbyqxmd.com/read/28329150/scoliosis-after-pectus-excavatum-correction-does-it-improve-or-worsen-%C3%A2
#1
Jae Ho Chung, Hyung Joo Park, Kwang Taik Kim
OBJECTIVES: Scoliosis is associated with pectus excavatum. However, the change in the degree of scoliosis after pectus excavatum correction has not been clarified. This study examined how the correction of pectus excavatum influences the status of pre-existing scoliosis. METHODS: A total of 779 pectus excavatum patients operated between 2007 and 2011 using the pectus bar were retrospectively analysed. Preoperative severity and postoperative change of scoliosis in accordance with the severity of pectus excavatum were evaluated...
March 7, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28321340/right-ventricular-compression-mimicking-brugada-like-electrocardiogram-in-a-patient-with-recurrent-pectus-excavatum
#2
Jinhee Ahn, Jong-Il Choi, Jaemin Shim, Sung Ho Lee, Young-Hoon Kim
Pectus excavatum (PE), the most common skeletal anomaly of chest wall, sometimes requires a surgical correction but recurrent PE is not uncommon. PE usually has a benign course; however, this chest deformity may be associated with symptomatic tachyarrhythmias due to mechanical compression. We report a case of a patient with recurrent PE after surgical correction presenting with palpitation and electrocardiogram (ECG) showing ST-segment elevation on the right precordial leads, which could be mistaken for a Brugada syndrome (BrS)...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28317635/a-depressed-heart-atrial-fibrillation-and-pulmonary-hypertension-in-severe-pectus-excavatum
#3
Sumit Som, Tatyana Danilov
No abstract text is available yet for this article.
April 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28304345/briarenols-c-e-new-polyoxygenated-briaranes-from-the-octocoral-briareum-excavatum
#4
Nan-Fu Chen, Yin-Di Su, Tsong-Long Hwang, Zuo-Jian Liao, Kuan-Hao Tsui, Zhi-Hong Wen, Yang-Chang Wu, Ping-Jyun Sung
Three new polyoxygenated briarane diterpenoids, briarenols C-E (1-3), were isolated from the octocoral Briareum excavatum. The structures of briaranes 1-3 were elucidated by interpretation of spectroscopic data, and the methylenecyclohexane ring in 1 was found to exist in a twisted boat conformation. Briarenol D (2) displayed an inhibitory effect on the release of elastase by human neutrophils with an IC50 value of 4.65 μM. Briarenol E (3) was found to inhibit the protein expression of pro-inflammatory inducible nitric oxide synthase (iNOS) in a murine macrophage-like cell line, RAW 264...
March 17, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28230898/manifestations-and-medicolegal-significance-of-loeys-dietz-syndrome
#5
Roger W Byard
Loeys-Dietz syndrome is a recently described autosomal dominant disorder with underlying vasculopathy characterized by aortic and other vascular aneurysmal dissection/rupture. A 61-year-old man is reported who died suddenly and unexpectedly and at autopsy was found to have a ruptured abdominal aortic aneurysm. Additional findings included dolichostenomelia, high-arched palate, and pectus excavatum. There was a strong family history of Loeys-Dietz syndrome, although the decedent had never been tested. Death was, therefore, due to a ruptured abdominal aortic aneurysm in a case of probable Loeys-Dietz syndrome...
February 23, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28230518/pectus-excavatum-first-ultrastructural-findings-of-a-potential-ciliopathy
#6
Christoph Brochhausen, Andreas Mamilos, Salmai Turial, C James Kirkpatrick
No abstract text is available yet for this article.
January 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28217231/successful-intermuscular-implantation-of-subcutaneous-implantable-cardioverter-defibrillator-in-a-japanese-patient-with-pectus-excavatum
#7
Yusuke Kondo, Marehiko Ueda, Joachim Winter, Miyo Nakano, Masahiro Nakano, Masayuki Ishimura, Kazuo Miyazawa, Kaoru Tateno, Yoshio Kobayashi
The entirely subcutaneous implantable cardioverter-defibrillator (ICD) system was developed to provide a life-saving defibrillation therapy that does not affect the heart and vasculature. The subcutaneous ICD is preferred over the transvenous ICD for patients with a history of recurrent infection presenting major life-threatening rhythms. In this case report, we describe the first successful intermuscular implantation of a completely subcutaneous ICD in a Japanese patient with pectus excavatum. There were no associated complications with the device implantation or lead positioning...
February 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28214505/positional-right-ventricular-obstruction-in-pectus-excavatum
#8
Katherine Underwood, Matthew Vorsanger, Muhamed Saric, Adam H Skolnick
Pectus excavatum is one of the most common congenital chest wall deformities. The degree of sternal depression, which may result in compression of the right heart by the chest wall, is variable. While typically asymptomatic, there are various symptoms that can result from severe pectus excavatum. We report on a patient with severe pectus excavatum leading to dynamic obstruction of the right ventricular outflow tract in the seated position.
January 25, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28202768/respiratory-morbidity-in-infants-born-with-a-congenital-lung-malformation
#9
Celine Delestrain, Naziha Khen-Dunlop, Alice Hadchouel, Pierrick Cros, Héloïse Ducoin, Michael Fayon, Isabelle Gibertini, André Labbé, Géraldine Labouret, Marie-Noëlle Lebras, Guillaume Lezmi, Fouad Madhi, Guillaume Thouvenin, Caroline Thumerelle, Christophe Delacourt
BACKGROUND AND OBJECTIVES: The actual frequency of respiratory symptoms related to congenital pulmonary malformations (CPMs) remains undetermined. The goal of this study was to prospectively evaluate the respiratory symptoms occurring in infants with prenatally diagnosed CPMs, identify factors associated with the occurrence of these symptoms, and evaluate their resolution after surgery. METHODS: Infectious and noninfectious respiratory symptoms were prospectively collected in a French multicenter cohort of children with CPMs...
February 15, 2017: Pediatrics
https://www.readbyqxmd.com/read/28163941/novel-pathogenic-variant-in-tgfbr2-confirmed-by-molecular-modeling-is-a-rare-cause-of-loeys-dietz-syndrome
#10
Michael T Zimmermann, Raul A Urrutia, Patrick R Blackburn, Margot A Cousin, Nicole J Boczek, Eric W Klee, Colleen Macmurdo, Paldeep S Atwal
Loeys-Dietz syndrome (LDS) is a connective tissue disorder characterized by vascular findings of aneurysm and/or dissection of cerebral, thoracic, or abdominal arteries and skeletal findings. We report a case of a novel pathogenic variant in TGFBR2 and phenotype consistent with classic LDS. The proband was a 10-year-old presenting to the genetics clinic with an enlarged aortic root (Z-scores 5-6), pectus excavatum, and congenital contractures of the right 2nd and 3rd digit. Molecular testing of TGFBR2 was sent to a commercial laboratory and demonstrated a novel, likely pathogenic, variant in exon 4, c...
2017: Case Reports in Genetics
https://www.readbyqxmd.com/read/28140622/exaggerated-interventricular-dependence-among-patients-with-pectus-excavatum-combined-assessment-with-cardiac-mri-and-chest-ct
#11
Alejandro Deviggiano, Javier Vallejos, Natalia Vina, Marcelo Martinez-Ferro, Gaston Bellia-Munzon, Patricia Carrascosa, Gaston A Rodríguez-Granillo
OBJECTIVE: We sought to explore whether patients with pectus excavatum have exaggerated interventricular dependence and to evaluate the impact of the malformation severity (assessed on CT) on both anatomic and functional cardiac parameters (assessed on cardiac MRI). SUBJECTS AND METHODS: The current study involved consecutive patients with a diagnosis of pectus excavatum who were referred to undergo cardiac MRI and chest CT to establish surgical candidacy or to define treatment strategies...
April 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28134952/pectus-excavatum-a-review-of-diagnosis-and-current-treatment-options
#12
Irfaan Abid, MennatAllah M Ewais, Joseph Marranca, Dawn E Jaroszewski
Osteopathic medicine places a special emphasis on the musculoskeletal system, and understanding how chest wall structure may influence function is critical. Pectus excavatum is a common congenital chest wall defect in which the sternum is depressed posteriorly. Patients may present with complaints of chest wall discomfort, exercise intolerance, and tachycardia. The medical implications, diagnosis, and treatment options for patients with pectus excavatum are reviewed.
February 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28124787/challenges-in-cardiac-surgery-how-to-operate-mitral-valve-in-patient-with-pectus-excavatum
#13
Wojciech Domaradzki, Krzysztof Sanetra, Witold Gerber, Bogdan Galar, Magdalena Zagrodzka
No abstract text is available yet for this article.
2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28094014/a-new-methodology-for-assessment-of-pectus-excavatum-correction-after-bar-removal-in-nuss-procedure-preliminary-study
#14
João Gomes-Fonseca, João L Vilaça, Tiago Henriques-Coelho, Bruno Direito-Santos, António C M Pinho, Jaime C Fonseca, Jorge Correia-Pinto
PURPOSE: The objective is to present a new methodology to assess quantitatively the impact of bar removal on the anterior chest wall, among patients with pectus excavatum who have undergone the Nuss procedure, and present a preliminary study using this methodology. METHODS: We propose to acquire, for each patient, the surface of the anterior chest wall using a three-dimensional laser scanner at subsequent time points (short term: before and after surgery; long term: follow-up visit, 6months, and 12months after surgery)...
January 7, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28087135/surgical-site-infection-related-to-use-of-elastomeric-pumps-in-pectus-excavatum-repair-lessons-learned-from-root-cause-analysis
#15
Nadja Apelt, Joshua Schaffzin, Christina Bates, Rebeccah L Brown, Marc Mecoli, Senthilkumar Sadhasivam, Victor Garcia
BACKGROUND: Pectus excavatum repair (PEX) is among the most painful thoracic procedures performed. Continuous peripheral nerve blockade (CPNB) is known to be efficacious in optimizing pain control while limiting narcotic use in adult thoracic procedures. It was introduced in May 2015 as a bridge to oral pain control in children undergoing PEX. Consequently, the surgical site infection (SSI) rate increased from 2.7% to 27.7%. METHODS: SSI surveillance followed national guidelines...
January 6, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28049606/an-insight-into-the-sialome-of-hyalomma-excavatum
#16
José M C Ribeiro, Mirko Slovák, Ivo M B Francischetti
Tick saliva contains hundreds or thousands of proteins that help blood feeding by impairing their hosts' hemostasis, inflammation and immunity. Salivary gland transcriptomes allow the disclosure of this pharmacologically active potion that consists of several multi-gene families, many of which are tick-specific. We here report the "de novo" assembly of ∼138 million reads deriving from a cDNA library from salivary glands of adult male and female Hyalomma excavatum leading to the public deposition of 5337 coding sequences to GenBank...
February 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28027271/reply-correction-of-pectus-excavatum-by-custom-made-silicone-implants-contribution-of-computer-aided-design-reconstruction-a-20-year-experience-and-401-cases
#17
Jean-Pierre Chavoin, Marcel Dahan, Elise Noel Savina, Alain Didier, Benoît Chaput
No abstract text is available yet for this article.
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27942495/erratum-to-ravitch-versus-nuss-procedure-for-pectus-excavatum-systematic-review-and-meta-analysis
#18
(no author information available yet)
[This corrects the article DOI: 10.21037/acs.2016.08.06.].
November 2016: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/27938890/hybrid-nuss-procedure-for-pectus-excavatum-with-severe-retrosternal-adhesions-after-sternotomy
#19
Shuai Li, Dehua Yang, Yazhen Ma, Shao-Tao Tang, Li Yang, Shiwang Li, Guoqing Cao, Kang Li, Xi Zhang, Xingjian Hu
BACKGROUND: The most striking feature of pectus excavatum (PE) after previous congenital heart disease (CHD) surgery through a median sternotomy is the postsurgical adhesions between the sternum and heart. For patients with severe adhesions, passing the introducer can be difficult and hazardous when performing a Nuss repair. We describe a hybrid Nuss procedure using a small subxiphoid incision for blunt and sharp anterior mediastinal dissection and using a thoracoscope to ensure the whole process of dissection is under direct visualization...
December 6, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27847075/combined-nuss-procedure-and-cardiac-procedure-through-a-left-anterolateral-thoracotomy
#20
François Roubertie, Sowmya Ramanan, Frederic Lavrand, Jean-Benoit Thambo
Aortic root aneurysms associated with severe pectus excavatum caused by Marfan's syndrome can be challenging to correct in children. Recent reports suggest single-stage correction of both cardiac and chest wall deformities through a median sternotomy. We report a 9-year-old girl with Marfan's syndrome, an ascending aorta aneurysm, mitral regurgitation, and pectus excavatum, who underwent David's procedure with mitral valve repair and the Nuss procedure to correct the thoracic deformity. This single-stage combined procedure was performed through a left anterolateral thoracotomy...
December 2016: Annals of Thoracic Surgery
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