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https://www.readbyqxmd.com/read/29678414/breast-reconstruction-after-mastectomy
#1
Thierry Tondu, Wiebren A A Tjalma, Filip E F Thiessen
Reconstructive surgery aims to improve quality of life by recreating a natural-looking breast that is warm to the touch. To obtain symmetry and body contour alignment, restoration of volume within the skin envelope is mandatory. The chosen reconstruction technique depends on the characteristics of the diseased breast, the shape and volume of the contralateral breast, and the technical skills of the surgical team. Timing, type and different possibilities of breast reconstruction are discussed.
April 14, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29678302/patient-reported-outcome-measures-in-breast-cancer-patients
#2
M Lagendijk, L S E van Egdom, C Richel, N van Leeuwen, C Verhoef, H F Lingsma, L B Koppert
INTRODUCTION: In the International Consortium for Health Outcome Measures (ICHOM) breast cancer outcome set Patient Reported Outcome Measurements (PROMs) form an important but rather innovative part. Few data exist on scores per type of breast surgery and how to use scores in surgical practice. We evaluated PROM scores as well as satisfaction with and expectations of the use of PROMs in breast cancer patients using the national and local patient advocate society. METHODS: Through an online survey patients were asked to report age, type of breast cancer surgery (whether Breast Conserving Therapy (BCT), mastectomy, autologous or implant breast reconstruction) and time since surgery...
March 21, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29678274/preoperative-mri-evaluation-of-lesion-nipple-distance-in-breast-cancer-patients-thresholds-for-predicting-occult-nipple-areola-complex-involvement
#3
G Mariscotti, M Durando, N Houssami, C M Berzovini, F Esposito, M Fasciano, P P Campanino, D Bosco, R Bussone, A Ala, I Castellano, A Sapino, L Bergamasco, P Fonio, G Gandini
AIM: To identify clinically occult nipple-areola complex (NAC) involvement using preoperative magnetic resonance imaging (MRI), to inform selection of patients eligible for nipple-sparing mastectomy (NSM) or skin-sparing mastectomy (SSM). MATERIAL AND METHODS: This was a retrospective study of 195 patients, who had preoperative breast MRI (February 2011 to January 2017) before undergoing surgical treatments (NSM or SSM) for newly diagnosed breast cancer. Tumour features at MRI (mass or non-mass lesion, diameter, lesion-NAC distance [LND]) and pathology (lesion diameter, histopathological type, receptor status) were recorded, as well as the type of surgery (NSM/SSM) and presence (NAC+) or absence (NAC-) of tumour at intraoperative evaluation of retroareolar tissue...
April 17, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29677398/does-stress-increase-risk-of-breast-cancer-a-15-year-prospective-study
#4
Phyllis Butow, Melanie Price, Joseph Coll, Katherine Tucker, Bettina Meiser, Roger Milne, Judith Wilson, Louise Heiniger, Brandi Baylock, Tracey Bullen, Prue Weideman, Kelly-Anne Phillips
OBJECTIVE: The possible impact of stress on cancer incidence remains controversial. We prospectively evaluated associations between life event stressors, social support, personality characteristics (optimism, anger control, anti-emotionality) and risk of developing primary breast cancer (BCa), in women at increased familial risk of BCa. METHODS: A prospective cohort, repeated measures design was employed. Recruitment was through the Kathleen Cuningham Foundation Consortium for Research into Familial breast cancer (kConFab), which collects genetic, epidemiological and clinical data from Australasian families with multiple BCa cases...
April 20, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29676352/comparison-of-lymphangiogenesis-lymphatic-invasion-and-axillary-lymph-node-metastasis-in-breast-carcinoma
#5
Prerna Guleria, V Srinivas, D Basannar, Vibha Dutta
Context: Lymphangiogenesis correlates with poor prognosis in Invasive Ductal Carcinoma (IDC) breast. D2-40 antibody, a specific marker for lymphatic endothelium, differentiates lymphatic from vascular endothelium. Therefore, the aims of this study were to estimate lymphangiogenesis using D2-40 antibody and correlate with lymphatic invasion (LI) and axillary lymph node (LN) status and compare lymphatic mean vessel density (LMVD) with Tumor (T) and Node (N) stages and grade of tumor. Methods and Material: The study was conducted on fifty consecutive cases of IDC breast who underwent modified radical mastectomy (MRM) from Jan 2009 to March 2011...
April 2018: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29674005/breast-cancer-cutaneous-metastases-mimicking-papilloma-cutis-lymphostatica-biopsy-to-avoid-pitfalls
#6
Giuseppe Giudice, Michelangelo Vestita, Fabio Robusto, Paolo Annoscia, Francesco Ciancio, Eleonora Nacchiero
INTRODUCTION: Secondary lymphedema is the most frequent long-term complication of axillary lymphadenectomy. It can result in complication as erysipelas, warts, Papilloma Cutis Lymphostatica (PCL), or angiosarcomas. Moreover, in women affected by breast cancer an accurate differential diagnosis among these conditions or complication related to radiation dermatitis or cutaneous metastasis is essential. PRESENTATION OF CASE: We report the case of a 60-year-old postmenopausal Caucasian woman affected by secondary lymphedema following complete mastectomy for breast cancer...
April 10, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29673384/prognostic-factors-of-radiation-dermatitis-following-passive-scattering-proton-therapy-for-breast-cancer
#7
Xiaoying Liang, Julie A Bradley, Dandan Zheng, Michael Rutenberg, Daniel Yeung, Nancy Mendenhall, Zuofeng Li
BACKGROUND: To identify prognostic factors for grade 3 radiation dermatitis following passive-scattering proton therapy for breast cancer. METHODS: This retrospective study included data on 23 (11 post-mastectomy and 12 post-lumpectomy) breast cancer patients who underwent proton therapy with the passive scattering technique in our institute from 2012 to 2016. Each patient received 50-50.4 cobalt Gy equivalent (CGE) at 1.8 or 2 CGE per daily fraction. Logistic regression analysis was performed to identify prognostic factors for grade 3 skin toxicity...
April 19, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/29672368/pectoral-i-block-does-not-improve-postoperative-analgesia-after-breast-cancer-surgery-a-randomized-double-blind-dual-centered-controlled-trial
#8
Jérôme Cros, Patrick Sengès, Suzan Kaprelian, Julie Desroches, Caroline Gagnon, Anaïs Labrunie, Benoît Marin, Sabrina Crépin, Nathalie Nathan, Pierre Beaulieu
BACKGROUND AND OBJECTIVES: General anesthesia for breast surgery may be supplemented by using a regional anesthetic technique. We evaluated the efficacy of the first pectoral nerve block (Pecs I) in treating postoperative pain after breast cancer surgery. METHODS: A randomized, double-blind, dual-centered, placebo-controlled trial was performed. One hundred twenty-eight patients scheduled for unilateral breast cancer surgery were recruited. A multimodal analgesic regimen and surgeon-administered local anesthetic infiltration were used for all patients...
April 18, 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29671735/how-tattoos-can-complement-breast-reconstruction
#9
Lisa Franczak
Tattooing offers expanded possibilities for creative expression for women who have undergone mastectomies and breast reconstruction surgeries. Tattoo techniques for areola restoration, such as repigmentation, do not address breast asymmetry or heavy scarring, but breast tattoos can embolden a woman's sexuality, self-confidence, and sense of body reclamation, as well as strengthen her postsurgical capacity for relating to her breasts and expressing her identity. There are many factors involved when a tattoo artist is asked to design an image for a patient...
April 1, 2018: AMA Journal of Ethics
https://www.readbyqxmd.com/read/29671138/nipple-sparing-mastectomy-is-not-associated-with-a-delay-of-adjuvant-treatment
#10
Emily L Albright, Mary C Schroeder, Kendra Foster, Sonia L Sugg, Lillian M Erdahl, Ronald J Weigel, Ingrid M Lizarraga
BACKGROUND: High-volume single-institution studies support the oncologic safety of nipple sparing mastectomy (NSM). Concerns remain regarding the increased potential for complications, recurrence, and delays to subsequent adjuvant therapy. A national database was used to examine treatment and outcomes for NSM patients. METHODS: Women undergoing unilateral NSM or skin sparing mastectomy (SSM) for stage 0-4 breast cancer from 2004 to 2013 were identified from the National Cancer Database...
April 18, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29670372/postmastectomy-radiotherapy-reduces-locoregional-and-disease-recurrence-in-patients-with-stage-ii-iii-triple-negative-breast-cancer-treated-with-neoadjuvant-chemotherapy-and-mastectomy
#11
Xingxing Chen, Fan Xia, Jurui Luo, Jinli Ma, Zhaozhi Yang, Li Zhang, Yan Feng, Zhimin Shao, Xiaoli Yu, Xiaomao Guo
Background: This study investigated the effect of postmastectomy radiotherapy (PMRT) in patients with stage II-III triple-negative breast cancer (TNBC) after neoadjuvant chemotherapy (NAC) and modified radical mastectomy (MRM). Patients and methods: A total of 104 women with stage II-III TNBC who received NAC and MRM at our institution between January 2000 and July 2007 were identified. Patients were divided into 2 groups (PMRT and non-PMRT) for statistical analysis...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29668607/successful-treatment-of-high-risk-myelodysplastic-syndrome-with-decitabine-based-chemotherapy-followed-by-haploidentical-lymphocyte-infusion-a-case-report-and-literature-review
#12
Yuanyuan Ma, Jianliang Shen, Li-Xin Wang
RATIONALE: The current therapy for elderly patients with high-risk myelodysplastic syndromes (MDSs) remains unsatisfactory. Decitabine, which has been approved to treat MDS, cannot eliminate malignant clones of MDS. PATIENT CONCERNS: A 68-year-old woman presented with multiple divergent bleeding points in the subcutaneous tissue of the limb. Two years earlier, she had been diagnosed with invasive ductal carcinoma of the left breast and had undergone left modified radical mastectomy and local radiation therapy...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29665804/immediate-implant-replacement-with-diep-flap-a-single-stage-salvage-option-in-failed-implant-based-breast-reconstruction
#13
Miguel De La Parra Marquez, Ricardo Fernandez-Riera, Hector Vela Cardona, Jesus María Rangel Flores
BACKGROUND: Implant-based immediate breast reconstruction after skin-sparing mastectomy has shown a significant improvement in patients' quality of life, making the procedure steadily more popular year after year. However, this technique has a high morbidity rate, including skin necrosis and implant exposure. METHODS: A retrospective review of a prospectively held database for autologous breast reconstruction in our institution of the last 5 years found eight cases with exposed implants after nipple-sparing mastectomy and immediate reconstruction...
April 17, 2018: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29664829/nipple-sparing-mastectomy-and-immediate-breast-reconstruction-with-a-deep-inferior-epigastric-perforator-flap-a-study-of-patient-satisfaction
#14
Jerry Levy, Romain Bosc, Noel Warren, Sabban Rebecca, Thu Ha Dao, Barbara Hersant, Jean-Paul Meningaud
INTRODUCTION: The morphological result of nipple-areola complex (NAC) reconstruction may be disappointing for patients who undergo skin-sparing mastectomies and immediate breast reconstruction, followed by secondary reconstruction of the nipple-areola complex.The aim of this study was to analyze patient satisfaction after nipple-sparing mastectomy and immediate breast reconstruction with a deep inferior epigastric perforator flap. MATERIALS AND METHODS: Our retrospective study involved all patients who underwent an immediate breast reconstruction after unilateral mastectomy with conservation of the NAC...
April 17, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29663320/predictors-of-complications-after-direct-to-implant-breast-reconstruction-with-an-acellular-dermal-matrix-from-a-multicentre-randomized-clinical-trial
#15
V L Negenborn, R E G Dikmans, M B Bouman, H A H Winters, J W R Twisk, P Q Ruhé, M A M Mureau, J M Smit, S Tuinder, J Hommes, Y Eltahir, N A S Posch, J M van Steveninck-Barends, M A Meesters-Caberg, R R W J van der Hulst, M J P F Ritt, M G Mullender
BACKGROUND: In the multicentre randomized trial BRIOS (Breast Reconstruction In One Stage), direct-to-implant (DTI) breast reconstruction with an acellular dermal matrix (ADM) was associated with a markedly higher postoperative complication rate compared with two-stage tissue expander/implant breast reconstruction. This study aimed to identify factors that contribute to the occurrence of complications after DTI ADM-assisted breast reconstruction. METHODS: Data were obtained from the BRIOS study, including all patients treated with DTI ADM-assisted breast reconstruction...
April 16, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29661737/a-rapid-triage-protocol-to-optimize-cold-ischemic-time-for-breast-resection-specimens
#16
Ellen G East, Matthew Gabbeart, Emily Roberts, Lili Zhao, Julie M Jorns
Prolonged time from specimen excision to adequate formalin exposure, or cold ischemic time (CIT), negatively impacts estrogen receptor (ER), progesterone receptor (PR) and HER-2 biomarker studies routinely performed on breast specimens. Current guidelines recommend CIT of ≤1 h. Since formalin penetrates resections slowly, optimal fixation requires incision. We evaluated the efficacy of a rapid triage protocol developed to optimize CIT. We identified 2821 specimens: 650 (23.0%) excisional biopsies (EB), 1051 (37...
March 6, 2018: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/29661153/improved-analgesia-and-reduced-post-operative-nausea-and-vomiting-after-implementation-of-an-enhanced-recovery-after-surgery-eras-pathway-for-total-mastectomy
#17
Catherine Chiu, Pedram Aleshi, Laura J Esserman, Christina Inglis-Arkell, Edward Yap, Elizabeth L Whitlock, Monica W Harbell
BACKGROUND: Enhanced Recovery After Surgery (ERAS) pathways have been shown in multiple surgical disciplines to improve outcomes, including reduced opioid consumption, length of stay, and post-operative nausea and vomiting (PONV). However, very few studies describe the application of ERAS to breast surgery and even fewer describe ERAS for outpatient surgery. We describe the implementation and efficacy of an Enhanced Recovery After Surgery (ERAS) pathway for total skin-sparing mastectomy with immediate reconstruction in an outpatient setting...
April 16, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29660760/racial-disparities-in-postmastectomy-breast-reconstruction-national-trends-in-utilization-from-2005-to-2014
#18
Sherise Epstein, Bao N Tran, Justin B Cohen, Samuel J Lin, Dhruv Singhal, Bernard T Lee
BACKGROUND: Evidence of racial disparities in the receipt of postmastectomy breast reconstruction is well documented. The objective of this study was to describe trends in racial disparities overall and by reconstructive technique. METHODS: The American College of Surgeons National Surgical Quality Improvement Program database was used to identify women who underwent mastectomy and/or breast reconstruction from 2005 to 2014. Patient demographics were recorded, and cases were grouped by reconstructive status and technique...
April 16, 2018: Cancer
https://www.readbyqxmd.com/read/29659451/the-use-of-surgical-delay-for-partial-mastectomy-reconstruction-in-the-previously-irradiated-breast-a-matched-control-case-series
#19
Steven A Schulz, Sumanas W Jordan, Albert H Chao
No abstract text is available yet for this article.
January 20, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29659449/evolution-in-monitoring-of-free-flap-autologous-breast-reconstruction-after-nipple-sparing-mastectomy-is-there-a-best-way
#20
Jordan D Frey, John T Stranix, Michael V Chiodo, Michael Alperovich, Christina Y Ahn, Robert J Allen, Mihye Choi, Nolan S Karp, Jamie P Levine
BACKGROUND: Free flap monitoring in autologous reconstruction after nipple-sparing mastectomy (NSM) remains controversial. We therefore examined outcomes in NSM with buried free flap reconstruction versus free flap reconstruction incorporating a monitoring skin paddle. METHODS: Autologous free flap reconstructions with NSM performed from 2006 to 2015 were identified. Demographics and operative results were analyzed and compared between buried flaps and those with a skin paddle for monitoring...
January 20, 2018: Plastic and Reconstructive Surgery
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