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https://www.readbyqxmd.com/read/27913487/venous-thromboembolism-and-stroke-in-pregnancy
#1
Kelley McLean, Mary Cushman
Pregnancy and the postpartum period substantially increase the risk for thrombotic events. Although the absolute risk for thrombosis is low, these events comprise a significant portion of maternal morbidity and mortality. The vast majority of such events are venous, although the risk for ischemic stroke also appears to be increased in pregnancy. This review will explore the overlapping and unique risk factors for venous and arterial thrombosis in pregnancy. Diagnosis and prevention will be discussed, and treatment will be briefly touched on...
December 2, 2016: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/27889462/maternal-and-umbilical-cord-blood-levels-of-mercury-manganese-iron-and-copper-in-southern-taiwan-a-cross-sectional-study
#2
Shih-Hui Huang, Ken-Pen Weng, Ching-Chiang Lin, Chung-Cheng Wang, Charles Tzu-Chi Lee, Luo-Ping Ger, Ming-Tsang Wu
BACKGROUND: The effect of maternal exposure to essential minerals and heavy metals on fetus is an important issue, which affects women around the world. Few data are available on the concentration of both essential minerals and heavy metals in maternal/fetal medicine. The aims of this study were to (1) assess the correlation of mercury (Hg), manganese (Mn), iron (Fe), and copper (Cu) in paired maternal/fetal blood samples, and (2) study potential confounding factors during pregnancy. METHODS: Our study recruited 145 healthy pregnant women with a mean age of 28...
November 23, 2016: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/27889258/unilateral-collaboration-the-practices-and-understandings-of-traditional-birth-attendants-in-southeastern-nigeria
#3
Magdalena Ohaja, Jo Murphy-Lawless
BACKGROUND: Despite the promotion of hospital-based maternity care as the safest option, for less developed countries, many women particularly those in the rural areas continue to patronise indigenous midwives or traditional birth attendants. Little is known about traditional birth attendants' perspectives regarding their pregnancy and birth practices. AIM: To explore traditional birth attendants' discourses of their pregnancy and birthing practices in southeast Nigeria...
November 23, 2016: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/27884128/a-randomised-controlled-demonstration-trial-of-multifaceted-nutritional-intervention-and-or-probiotics-the-healthy-mums-and-babies-humba-trial
#4
Karaponi Okesene-Gafa, Minglan Li, Rennae S Taylor, John M D Thompson, Caroline A Crowther, Christopher J D McKinlay, Lesley M E McCowan
BACKGROUND: Maternal obesity is associated with adverse pregnancy outcomes and has lifelong negative implications for offspring health. The Institute of Medicine recommends limited gestational weight gain (GWG) in obese women for optimal maternal and infant outcomes. However, there is a gap regarding an effective and sustainable intervention strategy to achieve this goal. The aim of the healthy mums and babies (HUMBA) demonstration trial is to assess whether a multifaceted nutritional intervention and/or an oral probiotic treatment in obese pregnant women can reduce excessive GWG and optimise pregnancy outcomes...
November 24, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27882748/-application-of-the-concetrations-ratio-of-soluble-receptor-tyrosine-kinase-type-1-and-placental-growth-factor-for-short-term-prediction-and-diagnosis-of-preeclampsia
#5
Š Bubeníková, A Cíchová, L Roubalová, V Durdová, R Vlk
OBJECTIVE: Bring a comprehensive overview of the available information about applications of the concetration ratio of soluble receptor tyrosine kinase type 1 (sFlt-1), and placental growth factor for short-term prediction and diagnosis of preeclampsia. DESIGN: Overview study. SETTINGS: Department of Midwifery, Faculty of Health Sciences, Olomouc; Department of Clinical Biochemistry, University Hospital Olomouc; Department of Obstetrics and Gynecology, University Hospital Olomouc; Department of Obstetrics and Gynecology, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27882745/-comparison-of-perinatal-mortality-in-slovak-republic-in-the-years-2007-2009-and-in-the-years-2010-2012
#6
M Korbeľ, A Krištúfková, M Borovský, J Danko, Z Nižňanská, P Kaščák, J Daniš
OBJECTIVE: Comparison of perinatal mortality in Slovak Republic in the years 2007-2009 and in the years 2010-2012. DESIGN: Epidemiological perinatal nation-wide. SETTING: 1st Department of Gynaecology and Obstetrics School of Medicine, Comenius University and University Hospital, Bratislava, Slovak Republic. METHODS: The analysis of selected perinatal data prospectively collected in the years 2007-2009 and in the years 2010-2012...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27875541/new-perspective-on-impact-of-folic-acid-supplementation-during-pregnancy-on-neurodevelopment-autism-in-the-offspring-children-a-systematic-review
#7
Yunfei Gao, Chao Sheng, Ri-Hua Xie, Wen Sun, Elizabeth Asztalos, Diane Moddemann, Lonnie Zwaigenbaum, Mark Walker, Shi Wu Wen
It has been conclusively established that folic acid supplementation prior to and during early pregnancy (up to 12 weeks of gestation) can prevent neural tube defects (NTDs). We hypothesized that folate effects may extend from neuro-structural defects to alterations in neuro-behavioural and emotional skills including autism spectrum disorders (ASDs) and other developmental disorders. The objective of this review was to comprehensively evaluate evidence on the impact of folic acid on neurodevelopment other than NTDs...
2016: PloS One
https://www.readbyqxmd.com/read/27874184/antenatal-ultrasound-features-in-fetuses-with-gastroschisis-and-its-prediction-in-neonatal-outcome
#8
Jessica A Robertson, Roy M Kimble, Kellie Stockton, Renuka Sekar
BACKGROUND: Gastroschisis is the most common major congenital anomaly managed by paediatric surgeons. The significance of certain associated antenatal ultrasound features in determining fetal outcome is under discussion. AIM: The study aims to define if associated antenatal ultrasound features of gastroschisis are useful prognostic markers for fetal outcome. By establishing the significance of features, including extra- and intra-abdominal bowel dilatation, stomach herniation, stomach dilatation, bowel matting, growth restriction, abnormal umbilical artery (UA) Doppler ultrasounds, and abnormal amniotic fluid volume, it is hoped clinicians will have enhanced ability to counsel parents about the likely outcomes for their infant...
November 22, 2016: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27872480/association-of-pre-pregnancy-body-mass-index-gestational-weight-gain-with-cesarean-section-in-term-deliveries-of-china
#9
Chao Xiong, Aifen Zhou, Zhongqiang Cao, Yaqi Zhang, Lin Qiu, Cong Yao, Youjie Wang, Bin Zhang
China has one of the highest rates of cesarean sections in the world. However, limited epidemiological studies have evaluated the risk factors for cesarean section among Chinese women. Thus, the aim of this cohort study was to investigate the associations between pre-pregnancy BMI, gestational weight gain (GWG) and the risk of cesarean section in China. A total of 57,891 women with singleton, live-born, term pregnancies were included in this analysis. We found that women who were overweight or obese before pregnancy had an elevated risk of cesarean section...
November 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27862084/intra-and-inter-observer-reproducibility-and-generalizability-of-first-trimester-uterine-artery-pulsatility-index-by-transabdominal-and-transvaginal-ultrasound
#10
Laura Marchi, Eva Zwertbroek, Judith Snelder, Maaike Kloosterman, Caterina Maddalena Bilardo
OBJECTIVES: The primary aim of the study was to assess intra-observer and inter-observer reproducibility and generalizability (general reliability) of first trimester Doppler measurements of uterine arteries (UtA) performed both transabdominally (TA) and transvaginally (TV). Secondary aims were to investigate whether maternal BMI and acquisition modality (transabdominal or transvaginal) affect feasibility and reliability of UtA Doppler evaluation. METHODS: Singleton pregnancies between 11(+0) and 13(+6) weeks underwent TA and TV Doppler measurements of UtA prospectively, blindly and independently by Fetal Medicine Foundation-accredited operators...
November 16, 2016: Prenatal Diagnosis
https://www.readbyqxmd.com/read/27859463/how-many-procedures-does-it-take-success-of-a-cvs-training-program-for-maternal-fetal-medicine-fellows
#11
Alexis C Gimovsky, Sindy C Moreno, Sara Nicholas, Amanda Roman, Stuart Weiner
OBJECTIVES: To quantify the learning curve for a training program for Maternal Fetal Medicine (MFM) fellows in obtaining successful transvaginal chorionic villus sampling (CVS) results in women with early pregnancy failure (EPF). METHODS: Retrospective observational cohort study of transvaginal CVS and subsequent manual vacuum aspiration (MVA) performed by MFM fellows. CVS samples were sent for karyotype, and products of conception (POC) were sent if CVS sample did not yield a result...
November 16, 2016: Prenatal Diagnosis
https://www.readbyqxmd.com/read/27855463/association-of-maternal-obesity-with-child-cerebral-palsy-or-death
#12
Jessica A McPherson, Marcela C Smid, Sarah Smiley, David M Stamilio
Objective The primary aim of this study was to determine if there is an association between maternal obesity and cerebral palsy or death in children. Study Design This is a retrospective cohort analysis of a randomized controlled clinical trial previously performed by the Maternal-Fetal Medicine Units Network. Women in the original trial were included if at high risk for preterm delivery. The present study included singletons enrolled in the original study with complete data. Obese and nonobese women were compared...
November 17, 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27854358/causes-of-death-in-prader-willi-syndrome-prader-willi-syndrome-association-usa-40-year-mortality-survey
#13
Merlin G Butler, Ann M Manzardo, Janalee Heinemann, Carolyn Loker, James Loker
BACKGROUND: Prader-Willi syndrome (PWS) is a rare, complex, neurodevelopmental genetic disorder that is associated with hyperphagia and morbid obesity in humans and leads to a shortened life expectancy. This report summarizes the primary causes of death and evaluates mortality trends in a large cohort of individuals with PWS. METHODS: The US Prader-Willi Syndrome Association (PWSA (USA)) syndrome-specific database of death reports was collected through a cursory bereavement program for PWSA (USA) families using a brief survey created in 1999...
November 17, 2016: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/27854131/perspectives-from-patients-and-healthcare-providers-on-the-practice-of-maternal-placentophagy
#14
Stephanie A Schuette, Kara M Brown, Danielle A Cuthbert, Cynthia W Coyle, Katherine L Wisner, M Camille Hoffman, Amy Yang, Jody D Ciolino, Rebecca L Newmark, Crystal T Clark
PURPOSE: Placentophagy (maternal consumption of the placenta) has become increasingly prevalent in the past decade among women seeking to promote health and healing during the postpartum period. The purpose of this study was to assess patient and provider familiarity with and attitudes toward placentophagy, as well as patients' willingness to try placentophagy. METHODS: Two cross-sectional surveys with questions regarding placentophagy practice were distributed to healthcare providers and patients...
November 17, 2016: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/27853988/antenatal-manifestations-of-inborn-errors-of-metabolism-prenatal-imaging-findings
#15
Laurent Guibaud, Sophie Collardeau-Frachon, Audrey Lacalm, Mona Massoud, Massimiliano Rossi, Marie Pierre Cordier, Christine Vianey-Saban
Prenatal manifestations of inborn errors of metabolism (IEM) are related to severe disorders involving metabolic pathways active in the fetal period and not compensated by maternal or placental metabolism. Some prenatal imaging findings can be suggestive of such conditions-especially in cases of consanguinity and/or recurrence of symptoms-after exclusion of the most frequent nonmetabolic etiologies. Most of these prenatal imaging findings are nonspecific. They include mainly ascites and hydrops fetalis, intrauterine growth restriction (IUGR), central nervous system (CNS) anomalies, echogenic kidneys, epiphyseal stippling, craniosynostosis, and a wide spectrum of dysostoses...
November 16, 2016: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/27847700/the-effect-of-ginger-extract-on-the-incidence-and-severity-of-nausea-and-vomiting-after-cesarean-section-under-spinal-anesthesia
#16
Hossein Zeraati, Javad Shahinfar, Shiva Imani Hesari, Mahnaz Masrorniya, Fatemeh Nasimi
BACKGROUND: Nausea and vomiting are one of the most common complications of cesarean sections under spinal anesthesia. Recently, the use of drugs to treat nausea and vomiting has decreased, and nonpharmaceutical and alternative traditional medicine are often preferred. OBJECTIVES: This study aimed to determine the effect of ginger extract on the incidence and severity of nausea and vomiting after cesarean section under spinal anesthesia. METHODS: In this double-blind randomized clinical trial, 92 pregnant women, each of whom underwent a cesarean section under spinal anesthesia, were divided in two groups: a control group and an intervention group...
October 2016: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/27836660/decreased-nutrient-intake-is-associated-with-premature-cervical-remodeling
#17
Mary Dawn Koenig, Barbara L McFarlin, Alana D Steffen, Lisa Tussing-Humphreys, Carmen Giurgescu, Christopher G Engeland, Michelle A Kominiarek, Christina Ciezczak-Karpiel, William D O'Brien, Rosemary White-Traut
OBJECTIVE: To examine the direct relationship between nutrient intake and cervical remodeling. DESIGN: Longitudinal descriptive design. SETTING: Maternal-fetal medicine clinic in a Midwestern urban city. PARTICIPANTS: Forty-seven pregnant African American women. METHODS: Participants completed the Block brief food frequency questionnaire at 19 to 24 weeks and 27 to 29 weeks gestation and had quantitative ultrasonic attenuation estimates at 19 to 21 weeks, 23 to 25 weeks, 27 to 29 weeks, 31 to 33 weeks, and 35 to 37 weeks gestation...
November 8, 2016: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/27836659/iron-metabolism-in-african-american-women-in-the-second-and-third-trimesters-of-high-risk-pregnancies
#18
Lauren Welke, Mary Dawn Koenig, Jessica L Thomson, Elizabeta Nemeth, Rosemary White-Traut, Barbara L McFarlin, Carmen Giurgescu, Christopher Engeland, Michelle A Kominiarek, Lisa Tussing-Humphreys
OBJECTIVE: To examine iron metabolism during the second and third trimesters in African American women with high-risk pregnancies. DESIGN: Longitudinal pilot study. SETTING: Large, university-based, urban Midwestern U.S. medical center. PARTICIPANTS: Convenience sample of 32 African American women with high-risk pregnancies seeking care at an urban maternal-fetal medicine clinic. METHODS: Nonfasting venous blood was collected in the second and third trimesters to assess iron status, hepcidin, and systemic inflammation...
November 8, 2016: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/27824768/relationship-between-excessive-gestational-weight-gain-and-neonatal-adiposity-in-women-with-mild-gestational-diabetes-mellitus
#19
Sean C Blackwell, Mark B Landon, Lisa Mele, Uma M Reddy, Brian M Casey, Ronald J Wapner, Michael W Varner, Dwight J Rouse, John M Thorp, Anthony Sciscione, Patrick Catalano, George Saade, Steve N Caritis, Yoram Sorokin, William A Grobman
OBJECTIVE: To evaluate the relationships among excessive gestational weight gain, neonatal adiposity, and adverse obstetric outcomes in women with mild gestational diabetes mellitus. METHODS: This is a secondary analysis of a multicenter randomized clinical trial of women with mild gestational diabetes mellitus. Based on self-reported prepregnancy body weight, gestational weight gain was categorized as excessive if it was greater than 2009 Institute of Medicine guidelines...
December 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27824747/social-contributors-to-glycemic-control-in-gestational-diabetes-mellitus
#20
Laura C Colicchia, Kristiina Parviainen, Judy C Chang
OBJECTIVE: To evaluate the association of social factors with glycemic control in women with gestational diabetes mellitus (GDM). METHODS: A survey instrument assessing social support, access to healthy food, cooking and meal preparation, chaotic lifestyle, employer support, and physical and emotional responses to food was developed and administered to women with GDM at maternal-fetal medicine office visits. Validated scales were used to measure social support and life chaos (defined as organization, instability, and the ability to plan and prepare for the future)...
December 2016: Obstetrics and Gynecology
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