Valéria Cristina Loureiro Salgado, Ronir Raggio Luiz, Neio Lucio Fernandes Boéchat, Isabella Sued Leão, Bianca do Carmo Schorr, José Miguel Luz Parente, Daniela Calado Lima, Eduardo Santos Silveira Júnior, Genoile Oliveira Santana Silva, Neogélia Pereira Almeida, Andrea Vieira, Maria Luiza Queiroz de Bueno, Júlio Maria Chebli, Érika Ruback Bertges, Luísa Martins da Costa Brugnara, Columbano Junqueira Neto, Stefania Burjack Gabriel Campbell, Luana Letiza Discacciati, João Paulo Silva Cézar, Tiago Nunes, Gilaad G Kaplan, Cyrla Zaltman
BACKGROUND: The etiology of inflammatory bowel disease (IBD) is unknown, but it is believed to be multifactorial. The hygiene hypothesis proposes that better hygiene conditions would lead to less infectious disease during childhood and favor the development of immune-mediated diseases. AIM: To test the hygiene hypothesis in IBD by assessing the environmental risk factors associated with IBD development in different regions of Brazil with diverse socioeconomic development indices...
July 7, 2020: World Journal of Gastroenterology: WJG